Karen Marie Arndt - Publications

Affiliations: 
1994- Biological Sciences University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology, Biochemistry, General Biology
Website:
https://www.biology.pitt.edu/person/karen-arndt

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fetian T, McShane BM, Horan NL, Shodja DN, True JD, Mosley AL, Arndt KM. Paf1 complex subunit Rtf1 stimulates H2B ubiquitylation by interacting with the highly conserved N-terminal helix of Rad6. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220041120. PMID 37216505 DOI: 10.1073/pnas.2220041120  0.616
2023 Ellison MA, Namjilsuren S, Shirra MK, Blacksmith MS, Schusteff RA, Kerr EM, Fang F, Xiang Y, Shi Y, Arndt KM. Spt6 directly interacts with Cdc73 and is required for Paf1 complex occupancy at active genes in Saccharomyces cerevisiae. Nucleic Acids Research. PMID 36928138 DOI: 10.1093/nar/gkad180  0.602
2021 Shirra MK, Kocik RA, Ellison MA, Arndt KM. Opposing functions of the Hda1 complex and histone H2B mono-ubiquitylation in regulating cryptic transcription in Saccharomyces cerevisiae. G3 (Bethesda, Md.). PMID 34499735 DOI: 10.1093/g3journal/jkab298  0.626
2021 Kaplan CD, Arndt KM. A PICture is worth a thousand words (and ten references). Cell. 184: 3850-3851. PMID 34297929 DOI: 10.1016/j.cell.2021.06.030  0.674
2021 Francette AM, Tripplehorn SA, Arndt KM. The Paf1 Complex: A Keystone of Nuclear Regulation Operating at the Interface of Transcription and Chromatin. Journal of Molecular Biology. 433: 166979. PMID 33811920 DOI: 10.1016/j.jmb.2021.166979  0.641
2020 Hildreth AE, Ellison MA, Francette AM, Seraly JM, Lotka LM, Arndt KM. The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription. Elife. 9. PMID 32845241 DOI: 10.7554/Elife.57757  0.633
2020 Hildreth AE, Ellison MA, Francette AM, Seraly JM, Lotka LM, Arndt KM. Author response: The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription Elife. DOI: 10.7554/Elife.57757.Sa2  0.519
2019 Cucinotta CE, Hildreth AE, McShane BM, Shirra MK, Arndt KM. The nucleosome acidic patch directly interacts with subunits of the Paf1 and FACT complexes and controls chromatin architecture in vivo. Nucleic Acids Research. PMID 31226204 DOI: 10.1093/Nar/Gkz549  0.845
2019 Ellison MA, Lederer AR, Warner MH, Mavrich TN, Raupach EA, Heisler LE, Nislow C, Lee MT, Arndt KM. The Paf1 Complex Broadly Impacts the Transcriptome of . Genetics. PMID 31092540 DOI: 10.1534/Genetics.119.302262  0.655
2017 Hildreth AE, Arndt KM. A transcriptional switch controls meiosis. Elife. 6. PMID 29063829 DOI: 10.7554/Elife.31911  0.409
2017 Van Oss SB, Cucinotta CE, Arndt KM. Emerging Insights into the Roles of the Paf1 Complex in Gene Regulation. Trends in Biochemical Sciences. PMID 28870425 DOI: 10.1016/J.Tibs.2017.08.003  0.842
2016 Van Oss SB, Shirra MK, Bataille AR, Wier AD, Yen K, Vinayachandran V, Byeon IL, Cucinotta CE, Héroux A, Jeon J, Kim J, VanDemark AP, Pugh BF, Arndt KM. The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6. Molecular Cell. PMID 27840029 DOI: 10.1016/J.Molcel.2016.10.008  0.847
2016 Cucinotta CE, Arndt KM. SnapShot: Transcription Elongation. Cell. 166: 1058-1058.e1. PMID 27518568 DOI: 10.1016/J.Cell.2016.07.039  0.855
2016 Raupach EA, Martens JA, Arndt KM. Evidence for Regulation of ECM3 Expression by Methylation of Histone H3 Lysine 4 and Intergenic Transcription in Saccharomyces cerevisiae. G3 (Bethesda, Md.). PMID 27449519 DOI: 10.1534/G3.116.033118  0.676
2015 Cucinotta CE, Young AN, Klucevsek KM, Arndt KM. The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae. Plos Genetics. 11: e1005420. PMID 26241481 DOI: 10.1371/Journal.Pgen.1005420  0.846
2015 Arndt KM, Reines D. Termination of Transcription of Short Noncoding RNAs by RNA Polymerase II. Annual Review of Biochemistry. 84: 381-404. PMID 25747400 DOI: 10.1146/Annurev-Biochem-060614-034457  0.799
2015 Cucinotta CE, Young AN, Klucevsek KM, Arndt KM. The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae Plos Genetics. 11. DOI: 10.1371/journal.pgen.1005420  0.816
2013 Wier AD, Mayekar MK, Héroux A, Arndt KM, VanDemark AP. Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proceedings of the National Academy of Sciences of the United States of America. 110: 17290-5. PMID 24101474 DOI: 10.1073/Pnas.1314754110  0.844
2013 Mayekar MK, Gardner RG, Arndt KM. The recruitment of the Saccharomyces cerevisiae Paf1 complex to active genes requires a domain of Rtf1 that directly interacts with the Spt4-Spt5 complex. Molecular and Cellular Biology. 33: 3259-73. PMID 23775116 DOI: 10.1128/Mcb.00270-13  0.848
2013 Tomson BN, Arndt KM. The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states. Biochimica Et Biophysica Acta. 1829: 116-26. PMID 22982193 DOI: 10.1016/J.Bbagrm.2012.08.011  0.659
2012 Piro AS, Mayekar MK, Warner MH, Davis CP, Arndt KM. Small region of Rtf1 protein can substitute for complete Paf1 complex in facilitating global histone H2B ubiquitylation in yeast. Proceedings of the National Academy of Sciences of the United States of America. 109: 10837-42. PMID 22699496 DOI: 10.1073/Pnas.1116994109  0.849
2012 Klucevsek KM, Braun MA, Arndt KM. The Paf1 complex subunit Rtf1 buffers cells against the toxic effects of [PSI+] and defects in Rkr1-dependent protein quality control in Saccharomyces cerevisiae. Genetics. 191: 1107-18. PMID 22595241 DOI: 10.1534/Genetics.112.141713  0.49
2012 Amrich CG, Davis CP, Rogal WP, Shirra MK, Heroux A, Gardner RG, Arndt KM, VanDemark AP. Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. The Journal of Biological Chemistry. 287: 10863-75. PMID 22318720 DOI: 10.1074/Jbc.M111.325647  0.72
2012 Crisucci EM, Arndt KM. Paf1 restricts Gcn4 occupancy and antisense transcription at the ARG1 promoter. Molecular and Cellular Biology. 32: 1150-63. PMID 22252319 DOI: 10.1128/Mcb.06262-11  0.825
2011 Crisucci EM, Arndt KM. The Roles of the Paf1 Complex and Associated Histone Modifications in Regulating Gene Expression. Genetics Research International. 2011. PMID 22408743 DOI: 10.4061/2011/707641  0.834
2011 Crisucci EM, Arndt KM. The Paf1 complex represses ARG1 transcription in Saccharomyces cerevisiae by promoting histone modifications. Eukaryotic Cell. 10: 712-23. PMID 21498644 DOI: 10.1128/Ec.05013-11  0.84
2011 Tomson BN, Davis CP, Warner MH, Arndt KM. Identification of a role for histone H2B ubiquitylation in noncoding RNA 3'-end formation through mutational analysis of Rtf1 in Saccharomyces cerevisiae. Genetics. 188: 273-89. PMID 21441211 DOI: 10.1534/Genetics.111.128645  0.822
2008 Shirra MK, McCartney RR, Zhang C, Shokat KM, Schmidt MC, Arndt KM. A chemical genomics study identifies Snf1 as a repressor of GCN4 translation. The Journal of Biological Chemistry. 283: 35889-98. PMID 18955495 DOI: 10.1074/Jbc.M805325200  0.454
2008 Rubenstein EM, McCartney RR, Zhang C, Shokat KM, Shirra MK, Arndt KM, Schmidt MC. Access denied: Snf1 activation loop phosphorylation is controlled by availability of the phosphorylated threonine 210 to the PP1 phosphatase. The Journal of Biological Chemistry. 283: 222-30. PMID 17991748 DOI: 10.1074/Jbc.M707957200  0.304
2007 Arndt KM. Molecular biology: genome under surveillance. Nature. 450: 959-60. PMID 18075570 DOI: 10.1038/450959A  0.342
2007 Chu Y, Simic R, Warner MH, Arndt KM, Prelich G. Regulation of histone modification and cryptic transcription by the Bur1 and Paf1 complexes. The Embo Journal. 26: 4646-56. PMID 17948059 DOI: 10.1038/Sj.Emboj.7601887  0.627
2007 Warner MH, Roinick KL, Arndt KM. Rtf1 is a multifunctional component of the Paf1 complex that regulates gene expression by directing cotranscriptional histone modification. Molecular and Cellular Biology. 27: 6103-15. PMID 17576814 DOI: 10.1128/Mcb.00772-07  0.714
2007 Braun MA, Costa PJ, Crisucci EM, Arndt KM. Identification of Rkr1, a nuclear RING domain protein with functional connections to chromatin modification in Saccharomyces cerevisiae. Molecular and Cellular Biology. 27: 2800-11. PMID 17283062 DOI: 10.1128/Mcb.01947-06  0.83
2005 Sheldon KE, Mauger DM, Arndt KM. A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation. Molecular Cell. 20: 225-36. PMID 16246725 DOI: 10.1016/J.Molcel.2005.08.026  0.852
2005 Arndt K, Winston F. An unexpected role for ubiquitylation of a transcriptional activator. Cell. 120: 733-4. PMID 15797373 DOI: 10.1016/J.Cell.2005.03.004  0.663
2005 Shirra MK, Rogers SE, Alexander DE, Arndt KM. The Snf1 protein kinase and Sit4 protein phosphatase have opposing functions in regulating TATA-binding protein association with the Saccharomyces cerevisiae INO1 promoter. Genetics. 169: 1957-72. PMID 15716495 DOI: 10.1534/Genetics.104.038075  0.583
2003 Arndt KM, Kane CM. Running with RNA polymerase: eukaryotic transcript elongation. Trends in Genetics : Tig. 19: 543-50. PMID 14550628 DOI: 10.1016/J.Tig.2003.08.008  0.528
2003 Simic R, Lindstrom DL, Tran HG, Roinick KL, Costa PJ, Johnson AD, Hartzog GA, Arndt KM. Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes. The Embo Journal. 22: 1846-56. PMID 12682017 DOI: 10.1093/Emboj/Cdg179  0.848
2002 Spencer JV, Arndt KM. A TATA binding protein mutant with increased affinity for DNA directs transcription from a reversed TATA sequence in vivo. Molecular and Cellular Biology. 22: 8744-55. PMID 12446791 DOI: 10.1128/Mcb.22.24.8744-8755.2002  0.41
2002 Squazzo SL, Costa PJ, Lindstrom DL, Kumer KE, Simic R, Jennings JL, Link AJ, Arndt KM, Hartzog GA. The Paf1 complex physically and functionally associates with transcription elongation factors in vivo. The Embo Journal. 21: 1764-74. PMID 11927560 DOI: 10.1093/Emboj/21.7.1764  0.779
2001 Shirra MK, Patton-Vogt J, Ulrich A, Liuta-Tehlivets O, Kohlwein SD, Henry SA, Arndt KM. Inhibition of acetyl coenzyme A carboxylase activity restores expression of the INO1 gene in a snf1 mutant strain of Saccharomyces cerevisiae Molecular and Cellular Biology. 21: 5710-5722. PMID 11486011 DOI: 10.1128/Mcb.21.17.5710-5722.2001  0.415
2000 Costa PJ, Arndt KM. Synthetic lethal interactions suggest a role for the Saccharomyces cerevisiae Rtf1 protein in transcription elongation. Genetics. 156: 535-47. PMID 11014804  0.815
2000 Liu Q, Gabriel SE, Roinick KL, Ward RD, Arndt KM. Analysis of TFIIA function In vivo: evidence for a role in TATA-binding protein recruitment and gene-specific activation. Molecular and Cellular Biology. 19: 8673-85. PMID 10567590 DOI: 10.1128/Mcb.19.12.8673  0.539
1997 Stolinski LA, Eisenmann DM, Arndt KM. Identification of RTF1, a novel gene important for TATA site selection by TATA box-binding protein in Saccharomyces cerevisiae. Molecular and Cellular Biology. 17: 4490-500. PMID 9234706 DOI: 10.1128/Mcb.17.8.4490  0.54
1995 Arndt KM, Ricupero-Hovasse S, Winston F. TBP mutants defective in activated transcription in vivo Embo Journal. 14: 1490-1497. PMID 7729424 DOI: 10.1002/J.1460-2075.1995.Tb07135.X  0.712
1994 Arndt KM, Wobbe CR, Ricupero-Hovasse S, Struhl K, Winston F. Equivalent mutations in the two repeats of yeast TATA-binding protein confer distinct TATA recognition specificities Molecular and Cellular Biology. 14: 3719-3728. PMID 8196615 DOI: 10.1128/mcb.14.6.3719-3728.1994  0.647
1992 Eisenmann DM, Arndt KM, Ricupero SL, Rooney JW, Winston F. SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae Genes and Development. 6: 1319-1331. PMID 1628834 DOI: 10.1101/Gad.6.7.1319  0.643
1992 Arndt KM, Ricupero SL, Eisenmann DM, Winston F. Biochemical and genetic characterization of a yeast TFIID mutant that alters transcription in vivo and DNA binding in vitro Molecular and Cellular Biology. 12: 2372-2382. PMID 1569955 DOI: 10.1128/mcb.12.5.2372-2382.1992  0.592
1990 Arndt KM, Chamberlin MJ. RNA chain elongation by Escherichia coli RNA polymerase. Factors affecting the stability of elongating ternary complexes. Journal of Molecular Biology. 213: 79-108. PMID 1692594 DOI: 10.1016/S0022-2836(05)80123-8  0.664
1988 Arndt KM, Chamberlin MJ. Transcription termination in Escherichia coli. Measurement of the rate of enzyme release from Rho-independent terminators. Journal of Molecular Biology. 202: 271-85. PMID 2459392 DOI: 10.1016/0022-2836(88)90457-3  0.642
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