Henrik Kacser, PhD - Publications

Affiliations: 
Genetics University of Edinburgh, Edinburgh, Scotland, United Kingdom 
Area:
Systems Biology, Genetics, Development

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1996 Kacser H, Small JR. How many phenotypes from one genotype? The case of Prion diseases. Journal of Theoretical Biology. 182: 209-18. PMID 8944151 DOI: 10.1006/jtbi.1996.0157  1
1995 Cascante M, Meléndez-Hevia E, Kholodenko B, Sicilia J, Kacser H. Control analysis of transit time for free and enzyme-bound metabolites: physiological and evolutionary significance of metabolic response times. The Biochemical Journal. 308: 895-9. PMID 8948448  1
1995 Kacser H. Recent developments beyond metabolic control analysis. Biochemical Society Transactions. 23: 387-91. PMID 7672420  1
1995 Kacser H, Burns JA. The control of flux. Biochemical Society Transactions. 23: 341-66. PMID 7672373  1
1994 Small JR, Kacser H. A method for increasing the concentration of a specific internal metabolite in steady-state systems. European Journal of Biochemistry / Febs. 226: 649-56. PMID 8001581 DOI: 10.1111/j.1432-1033.1994.tb20092.x  1
1993 Small JR, Kacser H. Responses of metabolic systems to large changes in enzyme activities and effectors. 2. The linear treatment of branched pathways and metabolite concentrations. Assessment of the general non-linear case. European Journal of Biochemistry / Febs. 213: 625-40. PMID 8477733  1
1993 Small JR, Kacser H. Responses of metabolic systems to large changes in enzyme activities and effectors. 1. The linear treatment of unbranched chains. European Journal of Biochemistry / Febs. 213: 613-24. PMID 8477732  1
1993 Kacser H, Acerenza L. A universal method for achieving increases in metabolite production. European Journal of Biochemistry / Febs. 216: 361-7. PMID 8375376  1
1993 Allison SM, Small JR, Kacser H, Prosser JI. Control analysis of microbial interactions in continuous culture: A simulation study Journal of General Microbiology. 139: 2309-2317.  1
1992 Niederberger P, Prasad R, Miozzari G, Kacser H. A strategy for increasing an in vivo flux by genetic manipulations. The tryptophan system of yeast. The Biochemical Journal. 287: 473-9. PMID 1445205  1
1991 Kacser H. A superior theory? Journal of Theoretical Biology. 149: 141-4. PMID 1881143 DOI: 10.1016/S0022-5193(05)80076-1  1
1990 Sauro HM, Kacser H. Enzyme-enzyme interactions and control analysis. 2. The case of non-independence: heterologous associations. European Journal of Biochemistry / Febs. 187: 493-500. PMID 2406133  1
1990 Kacser H, Sauro HM, Acerenza L. Enzyme-enzyme interactions and control analysis. 1. The case of non-additivity: monomer-oligomer associations. European Journal of Biochemistry / Febs. 187: 481-91. PMID 2406132  1
1990 Acerenza L, Kacser H. Enzyme kinetics and metabolic control. A method to test and quantify the effect of enzymic properties on metabolic variables. The Biochemical Journal. 269: 697-707. PMID 2390063  1
1990 Meléndez-Hevia E, Torres NV, Sicilia J, Kacser H. Control analysis of transition times in metabolic systems. The Biochemical Journal. 265: 195-202. PMID 2302166  1
1989 Acerenza L, Sauro HM, Kacser H. Control analysis of time-dependent metabolic systems. Journal of Theoretical Biology. 137: 423-44. PMID 2626059 DOI: 10.1016/S0022-5193(89)80038-4  1
1987 Keightley PD, Kacser H. Dominance, pleiotropy and metabolic structure. Genetics. 117: 319-29. PMID 3666444  1
1987 Kacser H. Dominance not inevitable but very likely. Journal of Theoretical Biology. 126: 505-6. PMID 3657243 DOI: 10.1016/S0022-5193(87)80155-8  1
1987 Kacser H, Porteous JW. Control of metabolism: What do we have to measure? Trends in Biochemical Sciences. 12: 5-14. DOI: 10.1016/0968-0004(87)90005-3  1
1987 Kacser H, Porteous JW. Reply to Welch and Keleti Trends in Biochemical Sciences. 12: 223.  1
1986 Hofmeyr JH, Kacser H, van der Merwe KJ. Metabolic control analysis of moiety-conserved cycles. European Journal of Biochemistry / Febs. 155: 631-41. PMID 3956502  1
1986 Torres NV, Mateo F, Meléndez-Hevia E, Kacser H. Kinetics of metabolic pathways. A system in vitro to study the control of flux. The Biochemical Journal. 234: 169-74. PMID 3707539  1
1986 Stuart F, Porteous DJ, Flint HJ, Kacser H. Control of the flux in the arginine pathway of Neurospora crassa: Effects of co-ordinate changes of enzyme concentration Journal of General Microbiology. 132: 1159-1166.  1
1985 Flint HJ, Dible S, Kacser H. Depression of enzyme synthesis in response to arginine limitation in Neurospora crassa. Journal of General Microbiology. 131: 2891-900. PMID 2936866  1
1985 Burns JA, Cornish-Bowden A, Groen AK, Heinrich R, Kacser H, Porteous JW, Rapoport SM, Rapoport TA, Stucki JW, Tager JM, Wanders RJA, Westerhoff HV. Control analysis of metabolic systems Trends in Biochemical Sciences. 10: 16. DOI: 10.1016/0968-0004(85)90008-8  1
1985 Flint HJ, Dible S, Kacser H. Derepression of enzyme synthesis in response to arginine limitation in Neurospora crassa Journal of General Microbiology. 131: 2891-2900.  1
1984 Kacser H, Beeby R. Evolution of catalytic proteins or on the origin of enzyme species by means of natural selection. Journal of Molecular Evolution. 20: 38-51. PMID 6429341 DOI: 10.1007/BF02101984  1
1983 Kacser H. The control of enzyme systems in vivo: elasticity analysis of the steady state. Biochemical Society Transactions. 11: 35-40. PMID 6825913  1
1983 Middleton RJ, Kacser H. Enzyme variation, metabolic flux and fitness: alcohol dehydrogenase in Drosophila melanogaster. Genetics. 105: 633-50. PMID 6416922  1
1983 Kacser H. Biochemists alcohol problem: a case of addiction to the wrong concepts? Trends in Biochemical Sciences. 8: 310-311. DOI: 10.1016/0968-0004(83)90096-8  1
1982 Wright AF, Bulfield G, Arfin SM, Kacser H. Comparison of the properties of histidine ammonia-lyase in normal and histidinemic mutant mice. Biochemical Genetics. 20: 245-63. PMID 7103928 DOI: 10.1007/BF00484422  1
1981 Kacser H, Burns JA. The molecular basis of dominance. Genetics. 97: 639-66. PMID 7297851  1
1981 Flint HJ, Tateson RW, Barthelmess IB, Porteous DJ, Donachie WD, Kacser H. Control of the flux in the arginine pathway of Neurospora crassa. Modulations of enzyme activity and concentration. The Biochemical Journal. 200: 231-46. PMID 6462136  1
1980 Flint HJ, Porteous DJ, Kacser H. Control of the flux in the arginine pathway of Neurospora crassa. The flux from citrulline to arginine. The Biochemical Journal. 190: 1-15. PMID 6449928  1
1979 Kacser H, Burns JA. MOlecular democracy: who shares the controls? Biochemical Society Transactions. 7: 1149-60. PMID 389705  1
1978 Bulfield G, Moore EA, Kacser H. Genetic variation in activity of the enzymes of glycolysis and gluconeogenesis between inbred strains of mice. Genetics. 89: 551-61. PMID 669257  1
1977 Kacser H, Mya KM, Duncker M, Wright AF, Bulfield G, McLaren A, Lyon MF. Maternal histidine metabolism and its effect on foetal development in the mouse. Nature. 265: 262-6. PMID 834272 DOI: 10.1038/265262a0  1
1977 Burns JA, Kacser H. Allosteric repression: an analysis. Journal of Theoretical Biology. 68: 199-213. PMID 412014 DOI: 10.1016/0022-5193(77)90159-X  1
1977 Kacser H, Bulfield G. Histidinemia Comparative Pathology Bulletin. 9: 3-4.  1
1976 Kacser H. The proper solutions of Kacser's developmental model. Journal of Theoretical Biology. 63: 239-41. PMID 1003995 DOI: 10.1016/0022-5193(76)90097-7  1
1976 Sang JH, Kacser H, Pritchard RH. Genetics at the OU Nature. 260: 745. DOI: 10.1038/260745a0  1
1976 Kacser H, Pritchard RH, Sano J. Genetics at the OU Nature. 260: 386-387. DOI: 10.1038/260386b0  1
1975 Bulfield G, Kacser H. Histamine and histidine levels in the brain of the histidinaemic mutant mouse. Journal of Neurochemistry. 24: 403-5. PMID 1113117  1
1974 Bulfield G, Kacser H. Histidinaemia in mouse and man. Archives of Disease in Childhood. 49: 545-52. PMID 4546820 DOI: 10.1136/adc.49.7.545  1
1974 Barthelmess IB, Curtis CF, Kacser H. Control of the flux to arginine in Neurospora crassa: de-repression of the last three enzymes of the arginine pathway. Journal of Molecular Biology. 87: 303-16. PMID 4279299 DOI: 10.1016/0022-2836(74)90151-X  1
1973 Kacser H, Bulfield G, Wallace ME. Histidinaemic mutant in the mouse. Nature. 244: 77-9. PMID 4583487 DOI: 10.1038/244077a0  1
1973 Kacser H, Burns JA. The control of flux. Symposia of the Society For Experimental Biology. 27: 65-104. PMID 4148886  1
1965 Burns JA, Curtis CF, Kacser H. A method for the production of a desired buffer gradient and its use for the chromatographic separation of argininosuccinate Journal of Chromatography A. 20: 310-318.  1
1957 BEALE GH, KACSER H. Studies on the antigens of Paramecium aurelia with the aid of fluorescent antibodies. Journal of General Microbiology. 17: 68-74. PMID 13475674  1
1956 Kacser H. Molecular Organization of Genetic Material. Science (New York, N.Y.). 124: 151-4. PMID 17843410 DOI: 10.1126/science.124.3213.151  1
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