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W. Brent Derry - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Website:
http://www.utoronto.ca/derrylab/index.php

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Abdelilah-Seyfried S, Tournier-Lasserve E, Derry WB. Blocking Signalopathic Events to Treat Cerebral Cavernous Malformations. Trends in Molecular Medicine. 26: 874-887. PMID 32692314 DOI: 10.1016/J.Molmed.2020.03.003  0.363
2019 Chapman EM, Lant B, Ohashi Y, Yu B, Schertzberg M, Go C, Dogra D, Koskimäki J, Girard R, Li Y, Fraser AG, Awad IA, Abdelilah-Seyfried S, Gingras AC, Derry WB. A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Nature Communications. 10: 1791. PMID 30996251 DOI: 10.1038/S41467-019-09829-Z  0.493
2019 Tran AT, Chapman EM, Flamand MN, Yu B, Krempel SJ, Duchaine TF, Eroglu M, Derry WB. MiR-35 buffers apoptosis thresholds in the C. elegans germline by antagonizing both MAPK and core apoptosis pathways. Cell Death and Differentiation. PMID 30952991 DOI: 10.1038/S41418-019-0325-6  0.437
2019 Koskimäki J, Girard R, Li Y, Saadat L, Zeineddine HA, Lightle R, Moore T, Lyne S, Avner K, Shenkar R, Cao Y, Shi C, Polster SP, Zhang D, Carrión-Penagos J, ... ... Derry WB, et al. Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes. Jci Insight. 4. PMID 30728328 DOI: 10.1172/Jci.Insight.126167  0.378
2018 Lant B, Pal S, Chapman EM, Yu B, Witvliet D, Choi S, Zhao L, Albiges-Rizo C, Faurobert E, Derry WB. Interrogating the ccm-3 Gene Network. Cell Reports. 24: 2857-2868.e4. PMID 30208312 DOI: 10.1016/J.Celrep.2018.08.039  0.396
2018 Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, Radetzki S, Vogt I, Hähn K, De Luca C, Cardoso C, Hamad S, Igual Gil C, Roy P, Albiges-Rizo C, ... ... Derry WB, et al. Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations. Embo Molecular Medicine. PMID 30181117 DOI: 10.15252/Emmm.201809155  0.318
2017 Pal S, Lant B, Yu B, Tian R, Tong J, Krieger JR, Moran MF, Gingras AC, Derry WB. CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity. Current Biology : Cb. PMID 28285997 DOI: 10.1016/J.Cub.2017.02.028  0.425
2016 Eroglu M, Derry WB. Your neighbours matter - non-autonomous control of apoptosis in development and disease. Cell Death and Differentiation. PMID 27177021 DOI: 10.1038/cdd.2016.41  0.322
2016 Mateo AF, Kessler Z, Jolliffe AK, McGovern O, Yu B, Nicolucci A, Yanowitz JL, Derry WB. The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans. Current Biology : Cb. PMID 27151662 DOI: 10.1016/J.Cub.2016.03.036  0.455
2014 Lant B, Derry WB. Immunostaining for markers of apoptosis in the Caenorhabditis elegans germline. Cold Spring Harbor Protocols. 2014. PMID 24786502 DOI: 10.1101/Pdb.Prot080242  0.375
2014 Lant B, Derry WB. Analysis of apoptosis in Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014. PMID 24786497 DOI: 10.1101/Pdb.Top070458  0.465
2014 Lant B, Derry WB. High-throughput RNAi screening for germline apoptosis genes in Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014: 428-34. PMID 24692493 DOI: 10.1101/Pdb.Prot080234  0.405
2014 Lant B, Derry WB. Fluorescent visualization of germline apoptosis in living Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014: 420-7. PMID 24692492 DOI: 10.1101/Pdb.Prot080226  0.394
2014 Lant B, Derry WB. Visualizing apoptosis in embryos and the germline of Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014: 278-83. PMID 24591691 DOI: 10.1101/Pdb.Prot080218  0.414
2014 Lant B, Derry WB. Induction of germline apoptosis in Caenorhabditis elegans. Cold Spring Harbor Protocols. 2014: 271-7. PMID 24591690 DOI: 10.1101/Pdb.Prot080192  0.397
2014 Baruah A, Chang H, Hall M, Yuan J, Gordon S, Johnson E, Shtessel LL, Yee C, Hekimi S, Derry WB, Lee SS. CEP-1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants. Plos Genetics. 10: e1004097. PMID 24586177 DOI: 10.1371/Journal.Pgen.1004097  0.423
2013 Leprivier G, Remke M, Rotblat B, Dubuc A, Mateo AR, Kool M, Agnihotri S, El-Naggar A, Yu B, Somasekharan SP, Faubert B, Bridon G, Tognon CE, Mathers J, Thomas R, ... ... Derry WB, et al. The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation. Cell. 153: 1064-79. PMID 23706743 DOI: 10.1016/J.Cell.2013.04.055  0.394
2013 Lant B, Derry WB. Methods for detection and analysis of apoptosis signaling in the C. elegans germline. Methods (San Diego, Calif.). 61: 174-82. PMID 23643851 DOI: 10.1016/J.Ymeth.2013.04.022  0.429
2013 Jolliffe AK, Derry WB. The TP53 signaling network in mammals and worms. Briefings in Functional Genomics. 12: 129-41. PMID 23165352 DOI: 10.1093/Bfgp/Els047  0.487
2011 Ceccarelli DF, Laister RC, Mulligan VK, Kean MJ, Goudreault M, Scott IC, Derry WB, Chakrabartty A, Gingras AC, Sicheri F. CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization. The Journal of Biological Chemistry. 286: 25056-64. PMID 21561863 DOI: 10.1074/Jbc.M110.213777  0.326
2011 Ross AJ, Li M, Yu B, Gao MX, Derry WB. The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans. Cell Death and Differentiation. 18: 1140-9. PMID 21233842 DOI: 10.1038/cdd.2010.180  0.469
2010 Ito S, Greiss S, Gartner A, Derry WB. Cell-nonautonomous regulation of C. elegans germ cell death by kri-1. Current Biology : Cb. 20: 333-8. PMID 20137949 DOI: 10.1016/J.Cub.2009.12.032  0.528
2008 Gao MX, Liao EH, Yu B, Wang Y, Zhen M, Derry WB. The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans. Cell Death and Differentiation. 15: 1054-62. PMID 18340346 DOI: 10.1038/Cdd.2008.30  0.482
2007 Taylor RC, Brumatti G, Ito S, Hengartner MO, Derry WB, Martin SJ. Establishing a blueprint for CED-3-dependent killing through identification of multiple substrates for this protease. The Journal of Biological Chemistry. 282: 15011-21. PMID 17371877 DOI: 10.1074/Jbc.M611051200  0.455
2007 Quevedo C, Kaplan DR, Derry WB. AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans. Current Biology : Cb. 17: 286-92. PMID 17276923 DOI: 10.1016/J.Cub.2006.12.038  0.528
2007 Derry WB, Bierings R, van Iersel M, Satkunendran T, Reinke V, Rothman JH. Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network. Cell Death and Differentiation. 14: 662-70. PMID 17186023 DOI: 10.1038/Sj.Cdd.4402075  0.629
2004 Huyen Y, Jeffrey PD, Derry WB, Rothman JH, Pavletich NP, Stavridi ES, Halazonetis TD. Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1. Structure (London, England : 1993). 12: 1237-43. PMID 15242600 DOI: 10.1016/J.Str.2004.05.007  0.561
2003 Fukuyama M, Gendreau SB, Derry WB, Rothman JH. Essential embryonic roles of the CKI-1 cyclin-dependent kinase inhibitor in cell-cycle exit and morphogenesis in C elegans. Developmental Biology. 260: 273-86. PMID 12885569 DOI: 10.1016/S0012-1606(03)00239-2  0.676
2001 Derry WB, Putzke AP, Rothman JH. Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance. Science (New York, N.Y.). 294: 591-5. PMID 11557844 DOI: 10.1126/Science.1065486  0.607
2001 Sugimoto A, Kusano A, Hozak RR, Derry WB, Zhu J, Rothman JH. Many genomic regions are required for normal embryonic programmed cell death in Caenorhabditis elegans. Genetics. 158: 237-52. PMID 11333233  0.622
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