| Year |
Citation |
Score |
| 2020 |
Rai G, Urban DJ, Mott BT, Hu X, Yang SM, Benavides GA, Johnson MS, Squadrito GL, Brimacombe KR, Lee TD, Cheff DM, Zhu H, Henderson MJ, Pohida K, Sulikowski GA, ... ... Sklar LA, et al. Pyrazole-Based Lactate Dehydrogenase (LDH) Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. Journal of Medicinal Chemistry. PMID 32902275 DOI: 10.1021/Acs.Jmedchem.0C00916 |
0.329 |
|
| 2020 |
Perez DR, Sklar LA, Chigaev A, Matlawska-Wasowska K. Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - a missed opportunity. Seminars in Cancer Biology. PMID 32044470 DOI: 10.1016/J.Semcancer.2020.02.004 |
0.316 |
|
| 2019 |
Revankar CM, Bologa CG, Pepermans RA, Sharma G, Petrie WK, Alcon SN, Field AS, Ramesh C, Parker MA, Savchuk NP, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling. Cell Chemical Biology. PMID 31706983 DOI: 10.1016/J.Chembiol.2019.10.009 |
0.713 |
|
| 2019 |
Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, et al. Autophagy, Inflammation, and Metabolism (AIM) Center in its second year. Autophagy. PMID 31234750 DOI: 10.1080/15548627.2019.1634444 |
0.615 |
|
| 2019 |
Tissino E, Bittolo T, Benedetti D, Bomben R, Härzschel A, Maity P, Forestieri G, Nicolò A, Datta M, Santinelli E, Rossi FM, Chigaev A, Sklar LA, Zaja F, Pozzato G, et al. The VLA-4 Integrin Is Constitutively Activated in a Fraction of CD49d-Expressing Chronic Lymphocytic Leukemia Via Autonomous BCR-Mediated Signaling Blood. 134: 849-849. DOI: 10.1182/Blood-2019-124313 |
0.361 |
|
| 2018 |
Sambrano J, Chigaev A, Nichani KS, Smagley Y, Sklar LA, Houston JP. Evaluating integrin activation with time-resolved flow cytometry. Journal of Biomedical Optics. 23: 1-10. PMID 29992797 DOI: 10.1117/1.Jbo.23.7.075004 |
0.369 |
|
| 2018 |
Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Sklar LA, Allers L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, Chen GC, Elazar Z, et al. Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations. Autophagy. PMID 29938597 DOI: 10.1080/15548627.2018.1465784 |
0.612 |
|
| 2018 |
Palsuledesai CC, Surviladze Z, Waller A, Miscioscia TF, Guo Y, Wu Y, Strouse J, Romero E, Salas VM, Curpan R, Young S, Carter M, Foutz T, Galochkina Z, Ames H, ... ... Sklar LA, et al. Activation of Rho-family GTPases by small molecules. Acs Chemical Biology. PMID 29746086 DOI: 10.1021/Acschembio.8B00038 |
0.359 |
|
| 2018 |
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, ... ... Sklar LA, et al. Unexplored therapeutic opportunities in the human genome. Nature Reviews. Drug Discovery. PMID 29472638 DOI: 10.1038/Nrd.2018.14 |
0.31 |
|
| 2018 |
Tissino E, Benedetti D, Herman SEM, Ten Hacken E, Ahn IE, Chaffee KG, Rossi FM, Dal Bo M, Bulian P, Bomben R, Bayer E, Härzschel A, Gutjahr JC, Postorino M, Santinelli E, ... ... Sklar LA, et al. Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia. The Journal of Experimental Medicine. PMID 29301866 DOI: 10.1084/Jem.20171288 |
0.323 |
|
| 2018 |
Haynes MK, Garcia M, Peters R, Waller A, Tedesco P, Ursu O, Bologa CG, Santos RG, Pinilla C, Wu TH, Lovchik JA, Oprea TI, Sklar LA, Tegos GP. High-Throughput Flow Cytometry Screening of Multidrug Efflux Systems. Methods in Molecular Biology (Clifton, N.J.). 1700: 293-318. PMID 29177837 DOI: 10.1007/978-1-4939-7454-2_16 |
0.334 |
|
| 2018 |
Tissino E, Bittolo T, Benedetti D, Bomben R, Forestieri G, Szenes E, Haerzschel A, Santinelli E, Rossi MF, Chigaev A, Sklar LA, Zaja F, Bulian P, D'Arena GF, Chiarenza A, et al. The VLA-4 Integrin Is Constitutively Activated in a Subset of CD49d-Expressing CLL: A Relationship with the Autonomous BCR-Mediated Signaling? Blood. 132: 5531-5531. DOI: 10.1182/Blood-2018-99-111450 |
0.357 |
|
| 2018 |
Nighot PK, Borunda T, Laidler L, Wong M, Thompson T, Oprea T, Sklar L, Ma TY. 264 - Tocopherylquinone-Mediated Activation of Aryl Hydrocarbon Receptor Reduces Intestinal Epithelial Tight Junction Permeability and Severity of Experimental Colitis Gastroenterology. 154: S-65. DOI: 10.1016/S0016-5085(18)30671-1 |
0.358 |
|
| 2017 |
Sambrano J, Smagley Y, Chigaev A, Sklar LA, Houston JP. Using FRET to quantify changes in integrin structures in human leukocytes induced by chemoattractants with multi-frequency flow cytometry Proceedings of Spie. 10065. DOI: 10.1117/12.2253340 |
0.334 |
|
| 2016 |
Perez D, Simons PC, Smagley Y, Sklar LA, Chigaev A. A High-Throughput Flow Cytometry Assay for Identification of Inhibitors of 3',5'-Cyclic Adenosine Monophosphate Efflux. Methods in Molecular Biology (Clifton, N.J.). 1439: 227-44. PMID 27316999 DOI: 10.1007/978-1-4939-3673-1_15 |
0.348 |
|
| 2016 |
Perez DR, Smagley Y, Garcia M, Carter MB, Evangelisti A, Matlawska-Wasowska K, Winter SS, Sklar LA, Chigaev A. ----Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia. Oncotarget. PMID 27129155 DOI: 10.18632/Oncotarget.8986 |
0.355 |
|
| 2015 |
Oprea TI, Sklar LA, Agola JO, Guo Y, Silberberg M, Roxby J, Vestling A, Romero E, Surviladze Z, Murray-Krezan C, Waller A, Ursu O, Hudson LG, Wandinger-Ness A. Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases. Plos One. 10: e0142182. PMID 26558612 DOI: 10.1371/Journal.Pone.0142182 |
0.303 |
|
| 2015 |
Wu Y, Stauffer SR, Stanfield RL, Tapia PH, Ursu O, Fisher GW, Szent-Gyorgyi C, Evangelisti A, Waller A, Strouse JJ, Carter MB, Bologa C, Gouveia K, Poslusney M, Waggoner AS, ... ... Sklar LA, et al. Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. Journal of Biomolecular Screening. PMID 26442911 DOI: 10.1177/1087057115609145 |
0.454 |
|
| 2015 |
Hong L, Guo Y, BasuRay S, Agola JO, Romero E, Simpson DS, Schroeder CE, Simons P, Waller A, Garcia M, Carter M, Ursu O, Gouveia K, Golden JE, Aubé J, ... ... Sklar LA, et al. A Pan-GTPase Inhibitor as a Molecular Probe. Plos One. 10: e0134317. PMID 26247207 DOI: 10.1371/Journal.Pone.0134317 |
0.357 |
|
| 2015 |
Guo Y, Kenney SR, Muller CY, Adams S, Rutledge T, Romero E, Murray-Krezan C, Prekeris R, Sklar LA, Hudson LG, Wandinger-Ness A. R-ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis. Molecular Cancer Therapeutics. PMID 26206334 DOI: 10.1158/1535-7163.Mct-15-0419 |
0.307 |
|
| 2015 |
Edwards BS, Sklar LA. Flow Cytometry: Impact on Early Drug Discovery. Journal of Biomolecular Screening. 20: 689-707. PMID 25805180 DOI: 10.1177/1087057115578273 |
0.352 |
|
| 2015 |
Agola JO, Sivalingam D, Cimino DF, Simons PC, Buranda T, Sklar LA, Wandinger-Ness A. Quantitative bead-based flow cytometry for assaying Rab7 GTPase interaction with the Rab-interacting lysosomal protein (RILP) effector protein. Methods in Molecular Biology (Clifton, N.J.). 1298: 331-54. PMID 25800855 DOI: 10.1007/978-1-4939-2569-8_28 |
0.376 |
|
| 2015 |
Zhao Z, Haynes MK, Ursu O, Edwards BS, Sklar LA, Zweifach A. A high-throughput phenotypic screen of cytotoxic T lymphocyte lytic granule exocytosis reveals candidate immunosuppressants. Journal of Biomolecular Screening. 20: 359-71. PMID 25381253 DOI: 10.1177/1087057114557620 |
0.353 |
|
| 2015 |
Chigaev A, Smagley Y, Haynes MK, Ursu O, Bologa CG, Halip L, Oprea T, Waller A, Carter MB, Zhang Y, Wang W, Buranda T, Sklar LA. FRET detection of lymphocyte function-associated antigen-1 conformational extension. Molecular Biology of the Cell. 26: 43-54. PMID 25378583 DOI: 10.1091/Mbc.E14-06-1050 |
0.352 |
|
| 2015 |
Guo Y, Kenney SR, Sklar LA, Buranda T, Oprea TI, Ursu O, Adams SF, Rutledge T, Muller C, Lomo L, Hudson LG, Wandinger-Ness A. Abstract 4044: R-ketorolac targets Cdc42 and Rac1 GTPases and alters ovarian tumor cell behaviors critical for invasion and metastasis Cancer Research. 75: 4044-4044. DOI: 10.1158/1538-7445.Am2015-4044 |
0.307 |
|
| 2014 |
Chigaev A, Smagley Y, Sklar LA. Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization. Bmc Immunology. 15: 52. PMID 25367365 DOI: 10.1186/S12865-014-0052-1 |
0.316 |
|
| 2014 |
Bernardo SM, Allen CP, Waller A, Young SM, Oprea T, Sklar LA, Lee SA. An automated high-throughput cell-based multiplexed flow cytometry assay to identify novel compounds to target Candida albicans virulence-related proteins. Plos One. 9: e110354. PMID 25350399 DOI: 10.1371/Journal.Pone.0110354 |
0.371 |
|
| 2014 |
Tegos GP, Evangelisti AM, Strouse JJ, Ursu O, Bologa C, Sklar LA. A high throughput flow cytometric assay platform targeting transporter inhibition. Drug Discovery Today. Technologies. 12: e95-103. PMID 25027381 DOI: 10.1016/J.Ddtec.2014.03.010 |
0.314 |
|
| 2014 |
Hong L, Sklar LA. Targeting GTPases in Parkinson's disease: comparison to the historic path of kinase drug discovery and perspectives. Frontiers in Molecular Neuroscience. 7: 52. PMID 24926233 DOI: 10.3389/Fnmol.2014.00052 |
0.326 |
|
| 2014 |
Smurthwaite CA, Hilton BJ, O'Hanlon R, Stolp ZD, Hancock BM, Abbadessa D, Stotland A, Sklar LA, Wolkowicz R. Fluorescent genetic barcoding in mammalian cells for enhanced multiplexing capabilities in flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 105-13. PMID 24700576 DOI: 10.1002/Cyto.A.22406 |
0.323 |
|
| 2014 |
Wu Y, Tapia PH, Jarvik J, Waggoner AS, Sklar LA. Real-time detection of protein trafficking with high-throughput flow cytometry (HTFC) and fluorogen-activating protein (FAP) base biosensor. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. 67: Unit 9.43.. PMID 24510772 DOI: 10.1002/0471142956.Cy0943S67 |
0.506 |
|
| 2014 |
Edwards BS, Gouveia K, Oprea TI, Sklar LA. The University of New Mexico Center for Molecular Discovery. Combinatorial Chemistry & High Throughput Screening. 17: 256-65. PMID 24409953 DOI: 10.2174/1386207317666140109123908 |
0.308 |
|
| 2014 |
Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, ... ... Sklar LA, et al. Erratum: Characterization of a CDC42 protein inhibitor and its use as a molecular probe (Journal of Biological Chemistry (2013) 288 (8531-8543)) Journal of Biological Chemistry. 289. DOI: 10.1074/Jbc.A112.435941 |
0.3 |
|
| 2013 |
Pinilla C, Edwards BS, Appel JR, Yates-Gibbins T, Giulianotti MA, Medina-Franco JL, Young SM, Santos RG, Sklar LA, Houghten RA. Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries. Molecular Pharmacology. 84: 314-24. PMID 23788657 DOI: 10.1124/Mol.113.086595 |
0.493 |
|
| 2013 |
Santos RG, Appel JR, Giulianotti MA, Edwards BS, Sklar LA, Houghten RA, Pinilla C. The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptors. Molecules (Basel, Switzerland). 18: 6408-24. PMID 23722730 DOI: 10.3390/Molecules18066408 |
0.398 |
|
| 2013 |
Medina-Franco JL, Edwards BS, Pinilla C, Appel JR, Giulianotti MA, Santos RG, Yongye AB, Sklar LA, Houghten RA. Rapid scanning structure-activity relationships in combinatorial data sets: identification of activity switches. Journal of Chemical Information and Modeling. 53: 1475-85. PMID 23705689 DOI: 10.1021/Ci400192Y |
0.321 |
|
| 2013 |
Strouse JJ, Ivnitski-Steele I, Waller A, Young SM, Perez D, Evangelisti AM, Ursu O, Bologa CG, Carter MB, Salas VM, Tegos G, Larson RS, Oprea TI, Edwards BS, Sklar LA. Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters. Analytical Biochemistry. 437: 77-87. PMID 23470221 DOI: 10.1016/J.Ab.2013.02.018 |
0.346 |
|
| 2013 |
Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, ... ... Sklar LA, et al. Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. The Journal of Biological Chemistry. 288: 8531-43. PMID 23382385 DOI: 10.1074/Jbc.M112.435941 |
0.351 |
|
| 2013 |
Wu Y, Tapia PH, Fisher GW, Waggoner AS, Jarvik J, Sklar LA. High-throughput flow cytometry compatible biosensor based on fluorogen activating protein technology. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 220-6. PMID 23303704 DOI: 10.1002/Cyto.A.22242 |
0.489 |
|
| 2013 |
Florian AE, Lepensky CK, Kwon O, Haynes MK, Sklar LA, Zweifach A. Flow cytometry enables a high-throughput homogeneous fluorescent antibody-binding assay for cytotoxic T cell lytic granule exocytosis. Journal of Biomolecular Screening. 18: 420-9. PMID 23160568 DOI: 10.1177/1087057112466697 |
0.378 |
|
| 2013 |
Strouse JJ, Ivnitski-Steele I, Khawaja HM, Perez D, Ricci J, Yao T, Weiner WS, Schroeder CE, Simpson DS, Maki BE, Li K, Golden JE, Foutz TD, Waller A, Evangelisti AM, ... ... Sklar LA, et al. A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry. Journal of Biomolecular Screening. 18: 26-38. PMID 22923785 DOI: 10.1177/1087057112456875 |
0.346 |
|
| 2013 |
Guo Y, Kenney SR, Romero E, Oprea T, Adams S, Muller C, Sklar L, Buranda T, Hudson L, Wandinger-Ness A. Abstract B81: Selected NSAIDs target GTPases for ovarian cancer therapy Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-B81 |
0.308 |
|
| 2012 |
Thal DM, Homan KT, Chen J, Wu EK, Hinkle PM, Huang ZM, Chuprun JK, Song J, Gao E, Cheung JY, Sklar LA, Koch WJ, Tesmer JJ. Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility. Acs Chemical Biology. 7: 1830-9. PMID 22882301 DOI: 10.1021/Cb3003013 |
0.399 |
|
| 2012 |
Chigaev A, Sklar LA. Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion. Frontiers in Immunology. 3: 242. PMID 22876249 DOI: 10.3389/Fimmu.2012.00242 |
0.403 |
|
| 2012 |
Polireddy K, Khan MM, Chavan H, Young S, Ma X, Waller A, Garcia M, Perez D, Chavez S, Strouse JJ, Haynes MK, Bologa CG, Oprea TI, Tegos GP, Sklar LA, et al. A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6. Plos One. 7: e40005. PMID 22808084 DOI: 10.1371/Journal.Pone.0040005 |
0.371 |
|
| 2012 |
Wu Y, Tapia PH, Fisher GW, Simons PC, Strouse JJ, Foutz T, Waggoner AS, Jarvik J, Sklar LA. Discovery of regulators of receptor internalization with high-throughput flow cytometry. Molecular Pharmacology. 82: 645-57. PMID 22767611 DOI: 10.1124/Mol.112.079897 |
0.522 |
|
| 2012 |
Agola JO, Hong L, Surviladze Z, Ursu O, Waller A, Strouse JJ, Simpson DS, Schroeder CE, Oprea TI, Golden JE, Aubé J, Buranda T, Sklar LA, Wandinger-Ness A. A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition. Acs Chemical Biology. 7: 1095-108. PMID 22486388 DOI: 10.1021/Cb3001099 |
0.347 |
|
| 2012 |
Edwards BS, Zhu J, Chen J, Carter MB, Thal DM, Tesmer JJ, Graves SW, Sklar LA. Cluster cytometry for high-capacity bioanalysis. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 419-29. PMID 22438314 DOI: 10.1002/Cyto.A.22039 |
0.33 |
|
| 2012 |
Chen J, Young SM, Allen C, Seeber A, Péli-Gulli MP, Panchaud N, Waller A, Ursu O, Yao T, Golden JE, Strouse JJ, Carter MB, Kang H, Bologa CG, Foutz TD, ... ... Sklar LA, et al. Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry. Acs Chemical Biology. 7: 715-22. PMID 22260433 DOI: 10.1021/Cb200452R |
0.375 |
|
| 2012 |
Surviladze Z, Young SM, Sklar LA. High-throughput flow cytometry bead-based multiplex assay for identification of Rho GTPase inhibitors. Methods in Molecular Biology (Clifton, N.J.). 827: 253-70. PMID 22144280 DOI: 10.1007/978-1-61779-442-1_17 |
0.396 |
|
| 2012 |
Chen J, Carter MB, Edwards BS, Cai H, Sklar LA. High throughput flow cytometry based yeast two-hybrid array approach for large-scale analysis of protein-protein interactions. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 90-8. PMID 21954189 DOI: 10.1002/Cyto.A.21144 |
0.351 |
|
| 2012 |
Chigaev A, Sklar LA. Overview: assays for studying integrin-dependent cell adhesion. Methods in Molecular Biology (Clifton, N.J.). 757: 3-14. PMID 21909902 DOI: 10.1007/978-1-61779-166-6_1 |
0.451 |
|
| 2012 |
Sykes DB, Haynes MK, Tolliday N, Waller A, Cobert JM, Szekely BA, Hasaka TP, Sklar L, Zon LI, Scadden DT. Identifying Small Molecules That Overcome HoxA9-Mediated Differentiation Arrest in Acute Myeloid Leukemia Blood. 120: 3513-3513. DOI: 10.1182/Blood.V120.21.3513.3513 |
0.383 |
|
| 2011 |
Zwartz GJ, Chigaev A, Foutz TD, Edwards B, Sklar LA. A miniature Couette to generate shear for flow cytometry: studying real-time modulation of intracellular calcium in monocytic cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 233-40. PMID 22045643 DOI: 10.1002/Cyto.A.21027 |
0.328 |
|
| 2011 |
Dennis MK, Field AS, Burai R, Ramesh C, Petrie WK, Bologa CG, Oprea TI, Yamaguchi Y, Hayashi S, Sklar LA, Hathaway HJ, Arterburn JB, Prossnitz ER. Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity. The Journal of Steroid Biochemistry and Molecular Biology. 127: 358-66. PMID 21782022 DOI: 10.1016/J.Jsbmb.2011.07.002 |
0.687 |
|
| 2011 |
Simons PC, Young SM, Carter MB, Waller A, Zhai D, Reed JC, Edwards BS, Sklar LA. Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples. Nature Protocols. 6: 943-52. PMID 21720309 DOI: 10.1038/Nprot.2011.339 |
0.365 |
|
| 2011 |
Chigaev A, Smagley Y, Sklar LA. Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion. Bmc Immunology. 12: 28. PMID 21586157 DOI: 10.1186/1471-2172-12-28 |
0.36 |
|
| 2011 |
Curpan RF, Simons PC, Zhai D, Young SM, Carter MB, Bologa CG, Oprea TI, Satterthwait AC, Reed JC, Edwards BS, Sklar LA. High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry. Assay and Drug Development Technologies. 9: 465-74. PMID 21561376 DOI: 10.1089/Adt.2010.0363 |
0.371 |
|
| 2011 |
Chigaev A, Smagley Y, Zhang Y, Waller A, Haynes MK, Amit O, Wang W, Larson RS, Sklar LA. Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4. The Journal of Biological Chemistry. 286: 20375-86. PMID 21515675 DOI: 10.1074/Jbc.M110.206185 |
0.448 |
|
| 2011 |
Tegos GP, Haynes M, Strouse JJ, Khan MM, Bologa CG, Oprea TI, Sklar LA. Microbial efflux pump inhibition: tactics and strategies. Current Pharmaceutical Design. 17: 1291-302. PMID 21470111 DOI: 10.2174/138161211795703726 |
0.311 |
|
| 2011 |
Davidson GS, Joe RM, Roy S, Meirelles O, Allen CP, Wilson MR, Tapia PH, Manzanilla EE, Dodson AE, Chakraborty S, Carter M, Young S, Edwards B, Sklar L, Werner-Washburne M. The proteomics of quiescent and nonquiescent cell differentiation in yeast stationary-phase cultures. Molecular Biology of the Cell. 22: 988-98. PMID 21289090 DOI: 10.1091/Mbc.E10-06-0499 |
0.306 |
|
| 2011 |
Gros R, Ding Q, Sklar LA, Prossnitz EE, Arterburn JB, Chorazyczewski J, Feldman RD. GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone. Hypertension. 57: 442-51. PMID 21242460 DOI: 10.1161/Hypertensionaha.110.161653 |
0.384 |
|
| 2011 |
Chigaev A, Wu Y, Williams DB, Smagley Y, Sklar LA. Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists. The Journal of Biological Chemistry. 286: 5455-63. PMID 21131351 DOI: 10.1074/Jbc.M110.162636 |
0.44 |
|
| 2011 |
Wandinger-Ness A, Kenney SR, Agola J, Roxby J, Surviladze Z, Silberberg M, Zeineldin R, Vestling A, Bologa C, Ursu O, Oprea T, Muller C, Lomo L, Sklar L, Hudson LG. Abstract LB-214: Rac1 and Cdc42 GTPases as novel targets in ovarian cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-214 |
0.315 |
|
| 2010 |
Saunders MJ, Edwards BS, Zhu J, Sklar LA, Graves SW. Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 13.12.1-17. PMID 20938917 DOI: 10.1002/0471142956.Cy1312S54 |
0.36 |
|
| 2010 |
Nayak TK, Dennis MK, Ramesh C, Burai R, Atcher RW, Sklar LA, Norenberg JP, Hathaway HJ, Arterburn JB, Prossnitz ER. Influence of charge on cell permeability and tumor imaging of GPR30-targeted 111in-labeled nonsteroidal imaging agents. Acs Chemical Biology. 5: 681-90. PMID 20486699 DOI: 10.1021/Cb1000636 |
0.697 |
|
| 2010 |
Burai R, Ramesh C, Shorty M, Curpan R, Bologa C, Sklar LA, Oprea T, Prossnitz ER, Arterburn JB. Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs. Organic & Biomolecular Chemistry. 8: 2252-9. PMID 20401403 DOI: 10.1039/C001307B |
0.651 |
|
| 2010 |
Buranda T, Wu Y, Perez D, Jett SD, BonduHawkins V, Ye C, Edwards B, Hall P, Larson RS, Lopez GP, Sklar LA, Hjelle B. Recognition of decay accelerating factor and alpha(v)beta(3) by inactivated hantaviruses: Toward the development of high-throughput screening flow cytometry assays. Analytical Biochemistry. 402: 151-60. PMID 20363206 DOI: 10.1016/J.Ab.2010.03.016 |
0.397 |
|
| 2010 |
Ramesh C, Nayak TK, Burai R, Dennis MK, Hathaway HJ, Sklar LA, Prossnitz ER, Arterburn JB. Synthesis and characterization of iodinated tetrahydroquinolines targeting the G protein-coupled estrogen receptor GPR30. Journal of Medicinal Chemistry. 53: 1004-14. PMID 20041667 DOI: 10.1021/Jm9011802 |
0.716 |
|
| 2010 |
Saunders MJ, Graves SW, Sklar LA, Oprea TI, Edwards BS. High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. Assay and Drug Development Technologies. 8: 37-46. PMID 20035615 DOI: 10.1089/Adt.2009.0219 |
0.329 |
|
| 2010 |
Johnson RM, Allen C, Melman SD, Waller A, Young SM, Sklar LA, Parra KJ. Identification of inhibitors of vacuolar proton-translocating ATPase pumps in yeast by high-throughput screening flow cytometry. Analytical Biochemistry. 398: 203-11. PMID 20018164 DOI: 10.1016/J.Ab.2009.12.020 |
0.321 |
|
| 2010 |
Surviladze Z, Waller A, Wu Y, Romero E, Edwards BS, Wandinger-Ness A, Sklar LA. Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay. Journal of Biomolecular Screening. 15: 10-20. PMID 20008126 DOI: 10.1177/1087057109352240 |
0.404 |
|
| 2009 |
Guo H, Yang J, Gallazzi F, Prossnitz ER, Sklar LA, Miao Y. Effect of DOTA position on melanoma targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide. Bioconjugate Chemistry. 20: 2162-8. PMID 19817405 DOI: 10.1021/Bc9003475 |
0.63 |
|
| 2009 |
Arterburn JB, Oprea TI, Prossnitz ER, Edwards BS, Sklar LA. Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30. Current Topics in Medicinal Chemistry. 9: 1227-36. PMID 19807662 DOI: 10.2174/156802609789753608 |
0.753 |
|
| 2009 |
Njus BH, Chigaev A, Waller A, Wlodek D, Ostopovici-Halip L, Ursu O, Wang W, Oprea TI, Bologa CG, Sklar LA. Conformational mAb as a tool for integrin ligand discovery. Assay and Drug Development Technologies. 7: 507-15. PMID 19754304 DOI: 10.1089/Adt.2009.0203 |
0.381 |
|
| 2009 |
Buranda T, Wu Y, Sklar LA. Chapter 11. Subsecond analyses of G-protein coupled-receptor ternary complex dynamics by rapid mix flow cytometry. Methods in Enzymology. 461: 227-47. PMID 19480922 DOI: 10.1016/S0076-6879(09)05411-1 |
0.431 |
|
| 2009 |
Haynes MK, Strouse JJ, Waller A, Leitao A, Curpan RF, Bologa C, Oprea TI, Prossnitz ER, Edwards BS, Sklar LA, Thompson TA. Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system. Journal of Biomolecular Screening. 14: 596-609. PMID 19470718 DOI: 10.1177/1087057109335671 |
0.667 |
|
| 2009 |
Dennis MK, Burai R, Ramesh C, Petrie WK, Alcon SN, Nayak TK, Bologa CG, Leitao A, Brailoiu E, Deliu E, Dun NJ, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, et al. In vivo effects of a GPR30 antagonist. Nature Chemical Biology. 5: 421-7. PMID 19430488 DOI: 10.1038/Nchembio.168 |
0.72 |
|
| 2009 |
Edwards BS, Young SM, Ivnitsky-Steele I, Ye RD, Prossnitz ER, Sklar LA. High-content screening: flow cytometry analysis. Methods in Molecular Biology (Clifton, N.J.). 486: 151-65. PMID 19347622 DOI: 10.1007/978-1-60327-545-3_11 |
0.729 |
|
| 2009 |
Chigaev A, Waller A, Amit O, Halip L, Bologa CG, Sklar LA. Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation. The Journal of Biological Chemistry. 284: 14337-46. PMID 19251697 DOI: 10.1074/Jbc.M901178200 |
0.416 |
|
| 2009 |
Strouse JJ, Young SM, Mitchell HD, Ye RD, Prossnitz ER, Sklar LA, Edwards BS. A novel fluorescent cross-reactive formylpeptide receptor/formylpeptide receptor-like 1 hexapeptide ligand. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 264-70. PMID 19006074 DOI: 10.1002/Cyto.A.20670 |
0.717 |
|
| 2009 |
Young SM, Bologa CM, Fara D, Bryant BK, Strouse JJ, Arterburn JB, Ye RD, Oprea TI, Prossnitz ER, Sklar LA, Edwards BS. Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 253-63. PMID 18785269 DOI: 10.1002/Cyto.A.20645 |
0.74 |
|
| 2008 |
Schwartz SL, Tessema M, Buranda T, Pylypenko O, Rak A, Simons PC, Surviladze Z, Sklar LA, Wandinger-Ness A. Flow cytometry for real-time measurement of guanine nucleotide binding and exchange by Ras-like GTPases. Analytical Biochemistry. 381: 258-66. PMID 18638444 DOI: 10.1016/J.Ab.2008.06.039 |
0.348 |
|
| 2008 |
Chigaev A, Waller A, Amit O, Sklar LA. Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion. Bmc Immunology. 9: 26. PMID 18534032 DOI: 10.1186/1471-2172-9-26 |
0.44 |
|
| 2008 |
Nayak TK, Hathaway HJ, Ramesh C, Arterburn JB, Dai D, Sklar LA, Norenberg JP, Prossnitz ER. Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 978-86. PMID 18483091 DOI: 10.2967/Jnumed.107.048546 |
0.643 |
|
| 2008 |
Prossnitz ER, Oprea TI, Sklar LA, Arterburn JB. The ins and outs of GPR30: a transmembrane estrogen receptor. The Journal of Steroid Biochemistry and Molecular Biology. 109: 350-3. PMID 18406603 DOI: 10.1016/J.Jsbmb.2008.03.006 |
0.707 |
|
| 2008 |
Dennis MK, Bowles HJ, MacKenzie DA, Burchiel SW, Edwards BS, Sklar LA, Prossnitz ER, Thompson TA. A multifunctional androgen receptor screening assay using the high-throughput Hypercyt flow cytometry system. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 390-9. PMID 18340645 DOI: 10.1002/Cyto.A.20552 |
0.704 |
|
| 2008 |
Winter SS, Lovato DM, Khawaja HM, Edwards BS, Steele ID, Young SM, Oprea TI, Sklar LA, Larson RS. High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agent. Journal of Biomolecular Screening. 13: 185-93. PMID 18310528 DOI: 10.1177/1087057108314610 |
0.315 |
|
| 2008 |
Prossnitz ER, Arterburn JB, Smith HO, Oprea TI, Sklar LA, Hathaway HJ. Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annual Review of Physiology. 70: 165-90. PMID 18271749 DOI: 10.1146/Annurev.Physiol.70.113006.100518 |
0.73 |
|
| 2008 |
Prossnitz ER, Sklar LA, Oprea TI, Arterburn JB. GPR30: a novel therapeutic target in estrogen-related disease. Trends in Pharmacological Sciences. 29: 116-23. PMID 18262661 DOI: 10.1016/J.Tips.2008.01.001 |
0.72 |
|
| 2008 |
Ivnitski-Steele I, Larson RS, Lovato DM, Khawaja HM, Winter SS, Oprea TI, Sklar LA, Edwards BS. High-throughput flow cytometry to detect selective inhibitors of ABCB1, ABCC1, and ABCG2 transporters. Assay and Drug Development Technologies. 6: 263-76. PMID 18205550 DOI: 10.1089/Adt.2007.107 |
0.309 |
|
| 2007 |
Edwards BS, Young SM, Saunders MJ, Bologa C, Oprea TI, Ye RD, Prossnitz ER, Graves SW, Sklar LA. High-throughput flow cytometry for drug discovery. Expert Opinion On Drug Discovery. 2: 685-96. PMID 23488958 DOI: 10.1517/17460441.2.5.685 |
0.681 |
|
| 2007 |
Edwards BS, Ivnitski-Steele I, Young SM, Salas VM, Sklar LA. High-throughput cytotoxicity screening by propidium iodide staining. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit9.24. PMID 18770858 DOI: 10.1002/0471142956.Cy0924S41 |
0.33 |
|
| 2007 |
Wu Y, Buranda T, Simons PC, Lopez GP, McIntire WE, Garrison JC, Prossnitz ER, Sklar LA. Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides. Analytical Biochemistry. 371: 10-20. PMID 17904091 DOI: 10.1016/J.Ab.2007.08.011 |
0.71 |
|
| 2007 |
Buranda T, Waller A, Wu Y, Simons PC, Biggs S, Prossnitz ER, Sklar LA. Some mechanistic insights into GPCR activation from detergent-solubilized ternary complexes on beads. Advances in Protein Chemistry. 74: 95-135. PMID 17854656 DOI: 10.1016/S0065-3233(07)74003-2 |
0.718 |
|
| 2007 |
Revankar CM, Mitchell HD, Field AS, Burai R, Corona C, Ramesh C, Sklar LA, Arterburn JB, Prossnitz ER. Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30. Acs Chemical Biology. 2: 536-44. PMID 17655271 DOI: 10.1021/Cb700072N |
0.733 |
|
| 2007 |
Sklar LA, Carter MB, Edwards BS. Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening Current Opinion in Pharmacology. 7: 527-534. PMID 17652026 DOI: 10.1016/J.Coph.2007.06.006 |
0.402 |
|
| 2007 |
Simons PC, Young SM, Gibaja V, Lee WC, Josiah S, Edwards BS, Sklar LA. Duplexed, bead-based competitive assay for inhibitors of protein kinases. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 451-9. PMID 17542028 DOI: 10.1002/Cyto.A.20398 |
0.303 |
|
| 2007 |
Chigaev A, Waller A, Zwartz GJ, Buranda T, Sklar LA. Regulation of cell adhesion by affinity and conformational unbending of alpha4beta1 integrin. Journal of Immunology (Baltimore, Md. : 1950). 178: 6828-39. PMID 17513731 DOI: 10.4049/Jimmunol.178.11.6828 |
0.409 |
|
| 2007 |
Brailoiu E, Dun SL, Brailoiu GC, Mizuo K, Sklar LA, Oprea TI, Prossnitz ER, Dun NJ. Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. The Journal of Endocrinology. 193: 311-21. PMID 17470522 DOI: 10.1677/Joe-07-0017 |
0.689 |
|
| 2007 |
DiVietro JA, Brown DC, Sklar LA, Larson RS, Lawrence MB. Immobilized stromal cell-derived factor-1alpha triggers rapid VLA-4 affinity increases to stabilize lymphocyte tethers on VCAM-1 and subsequently initiate firm adhesion. Journal of Immunology (Baltimore, Md. : 1950). 178: 3903-11. PMID 17339490 DOI: 10.4049/Jimmunol.178.6.3903 |
0.318 |
|
| 2007 |
Prossnitz ER, Arterburn JB, Sklar LA. GPR30: A G protein-coupled receptor for estrogen. Molecular and Cellular Endocrinology. 265: 138-42. PMID 17222505 DOI: 10.1016/J.Mce.2006.12.010 |
0.715 |
|
| 2007 |
Mills DA, Brown DC, Ramirez S, Chigaev A, Sklar LA, Laurence M, Larson RS. MOLECULAR REQUIREMENTS FOR VLA-4-MEDIATED B-LYMPHOCYTE ADHERENCE UNDER FLOW CONDITIONS. Journal of Investigative Medicine. 55: S120. DOI: 10.1097/00042871-200701010-00276 |
0.331 |
|
| 2006 |
Fara DC, Oprea TI, Prossnitz ER, Bologa CG, Edwards BS, Sklar LA. Integration of virtual and physical screening. Drug Discovery Today. Technologies. 3: 377-385. PMID 38620118 DOI: 10.1016/j.ddtec.2006.11.003 |
0.618 |
|
| 2006 |
Prossnitz ER, Arterburn JB, Edwards BS, Sklar LA, Oprea TI. Steroid-binding G-protein-coupled receptors: new drug discovery targets for old ligands. Expert Opinion On Drug Discovery. 1: 137-50. PMID 23495797 DOI: 10.1517/17460441.1.2.137 |
0.714 |
|
| 2006 |
Prossnitz ER, Sklar LA. Modulation of GPCR conformations by ligands, G-proteins, and arrestins. Ernst Schering Foundation Symposium Proceedings. 211-28. PMID 17703584 |
0.708 |
|
| 2006 |
Edwards BS, Young SM, Oprea TI, Bologa CG, Prossnitz ER, Sklar LA. Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform. Nature Protocols. 1: 59-66. PMID 17406212 DOI: 10.1038/Nprot.2006.9 |
0.751 |
|
| 2006 |
Ramesh C, Bryant B, Nayak T, Revankar CM, Anderson T, Carlson KE, Katzenellenbogen JA, Sklar LA, Norenberg JP, Prossnitz ER, Arterburn JB. Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates. Journal of the American Chemical Society. 128: 14476-7. PMID 17090028 DOI: 10.1021/Ja066360P |
0.733 |
|
| 2006 |
Tessema M, Simons PC, Cimino DF, Sanchez L, Waller A, Posner RG, Wandinger-Ness A, Prossnitz ER, Sklar LA. Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 326-34. PMID 16604533 DOI: 10.1002/Cyto.A.20259 |
0.66 |
|
| 2006 |
Wu Y, Buranda T, Metzenberg RL, Sklar LA, Lopez GP. Diazo coupling method for covalent attachment of proteins to solid substrates. Bioconjugate Chemistry. 17: 359-65. PMID 16536466 DOI: 10.1021/Bc050278M |
0.335 |
|
| 2006 |
Bologa CG, Revankar CM, Young SM, Edwards BS, Arterburn JB, Kiselyov AS, Parker MA, Tkachenko SE, Savchuck NP, Sklar LA, Oprea TI, Prossnitz ER. Virtual and biomolecular screening converge on a selective agonist for GPR30. Nature Chemical Biology. 2: 207-12. PMID 16520733 DOI: 10.1038/Nchembio775 |
0.738 |
|
| 2006 |
Okun I, Malarchuk S, Dubrovskaya E, Khvat A, Tkachenko S, Kysil V, Ilyin A, Kravchenko D, Prossnitz ER, Sklar L, Ivachtchenko A. Screening for caspase-3 inhibitors: a new class of potent small-molecule inhibitors of caspase-3. Journal of Biomolecular Screening. 11: 277-85. PMID 16490769 DOI: 10.1177/1087057105285048 |
0.644 |
|
| 2006 |
Winter SS, Lovato DM, Khawaja HM, Edwards BS, Steele ID, Young SM, Oprea TI, Sklar LA, Larson RS. Identification of Off-Patent Drugs That Reverse Daunorubicin Efflux Mediated by ABCB1 in T-ALL Cells. Blood. 108: 2603-2603. DOI: 10.1182/Blood.V108.11.2603.2603 |
0.312 |
|
| 2006 |
Fara DC, Oprea TI, Prossnitz ER, Bologa CG, Edwards BS, Sklar LA. Integration of virtual and physical screening Drug Discovery Today: Technologies. 3: 377-385. DOI: 10.1016/J.Ddtec.2006.11.003 |
0.648 |
|
| 2005 |
Edwards BS, Bologa C, Young SM, Balakin KV, Prossnitz ER, Savchuck NP, Sklar LA, Oprea TI. Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists. Molecular Pharmacology. 68: 1301-10. PMID 16118363 DOI: 10.1124/Mol.105.014068 |
0.72 |
|
| 2005 |
Oprea TI, Bologa CG, Edwards BS, Prossnitz ER, Sklar LA. Post-high-throughput screening analysis: an empirical compound prioritization scheme. Journal of Biomolecular Screening. 10: 419-26. PMID 16093551 DOI: 10.1177/1087057104272660 |
0.663 |
|
| 2005 |
Wu Y, Zwartz G, Lopez GP, Sklar LA, Buranda T. Small-volume rapid-mix device for subsecond kinetic analysis in flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 67: 37-44. PMID 16082710 DOI: 10.1002/Cyto.A.20171 |
0.36 |
|
| 2005 |
Young SM, Bologa C, Prossnitz ER, Oprea TI, Sklar LA, Edwards BS. High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands. Journal of Biomolecular Screening. 10: 374-82. PMID 15964939 DOI: 10.1177/1087057105274532 |
0.724 |
|
| 2005 |
Wu Y, Simons PC, Lopez GP, Sklar LA, Buranda T. Dynamics of fluorescence dequenching of ostrich-quenched fluorescein biotin: a multifunctional quantitative assay for biotin. Analytical Biochemistry. 342: 221-8. PMID 15913533 DOI: 10.1016/J.Ab.2005.03.046 |
0.319 |
|
| 2005 |
Larson RS, Davis T, Bologa C, Semenuk G, Vijayan S, Li Y, Oprea T, Chigaev A, Buranda T, Wagner CR, Sklar LA. Dissociation of I domain and global conformational changes in LFA-1: refinement of small molecule-I domain structure-activity relationships. Biochemistry. 44: 4322-31. PMID 15766261 DOI: 10.1021/Bi048187K |
0.35 |
|
| 2005 |
Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science (New York, N.Y.). 307: 1625-30. PMID 15705806 DOI: 10.1126/Science.1106943 |
0.718 |
|
| 2005 |
Key TA, Vines CM, Wagener BM, Gurevich VV, Sklar LA, Prossnitz ER. Inhibition of chemoattractant N-formyl peptide receptor trafficking by active arrestins. Traffic (Copenhagen, Denmark). 6: 87-99. PMID 15634210 DOI: 10.1111/J.1600-0854.2004.00248.X |
0.815 |
|
| 2004 |
Waller A, Simons PC, Biggs SM, Edwards BS, Prossnitz ER, Sklar LA. Techniques: GPCR assembly, pharmacology and screening by flow cytometry. Trends in Pharmacological Sciences. 25: 663-9. PMID 15530645 DOI: 10.1016/J.Tips.2004.10.009 |
0.729 |
|
| 2004 |
Piyasena ME, Buranda T, Wu Y, Huang J, Sklar LA, Lopez GP. Near-simultaneous and real-time detection of multiple analytes in affinity microcolumns. Analytical Chemistry. 76: 6266-73. PMID 15516117 DOI: 10.1021/Ac049260F |
0.406 |
|
| 2004 |
Edwards BS, Oprea T, Prossnitz ER, Sklar LA. Flow cytometry for high-throughput, high-content screening. Current Opinion in Chemical Biology. 8: 392-8. PMID 15288249 DOI: 10.1016/J.Cbpa.2004.06.007 |
0.714 |
|
| 2004 |
Bartsch JW, Tran HD, Waller A, Mammoli AA, Buranda T, Sklar LA, Edwards BS. An investigation of liquid carryover and sample residual for a high-throughput flow cytometer sample delivery system. Analytical Chemistry. 76: 3810-7. PMID 15228359 DOI: 10.1021/Ac049870F |
0.334 |
|
| 2004 |
Zwartz GJ, Chigaev A, Dwyer DC, Foutz TD, Edwards BS, Sklar LA. Real-time analysis of very late antigen-4 affinity modulation by shear. The Journal of Biological Chemistry. 279: 38277-86. PMID 15226304 DOI: 10.1074/Jbc.M402944200 |
0.358 |
|
| 2004 |
Hernandez-Hansen V, Smith AJ, Surviladze Z, Chigaev A, Mazel T, Kalesnikoff J, Lowell CA, Krystal G, Sklar LA, Wilson BS, Oliver JM. Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 100-12. PMID 15210764 DOI: 10.4049/Jimmunol.173.1.100 |
0.347 |
|
| 2004 |
Chigaev A, Zwartz GJ, Buranda T, Edwards BS, Prossnitz ER, Sklar LA. Conformational regulation of alpha 4 beta 1-integrin affinity by reducing agents. "Inside-out" signaling is independent of and additive to reduction-regulated integrin activation. The Journal of Biological Chemistry. 279: 32435-43. PMID 15166232 DOI: 10.1074/Jbc.M404387200 |
0.704 |
|
| 2004 |
Young SM, Curry MS, Ransom JT, Ballesteros JA, Prossnitz ER, Sklar LA, Edwards BS. High-throughput microfluidic mixing and multiparametric cell sorting for bioactive compound screening. Journal of Biomolecular Screening. 9: 103-11. PMID 15006133 DOI: 10.1177/1087057103262335 |
0.685 |
|
| 2004 |
Simons PC, Biggs SM, Waller A, Foutz T, Cimino DF, Guo Q, Neubig RR, Tang WJ, Prossnitz ER, Sklar LA. Real-time analysis of ternary complex on particles: direct evidence for partial agonism at the agonist-receptor-G protein complex assembly step of signal transduction. The Journal of Biological Chemistry. 279: 13514-21. PMID 14726530 DOI: 10.1074/Jbc.M310306200 |
0.73 |
|
| 2003 |
Chigaev A, Buranda T, Dwyer DC, Prossnitz ER, Sklar LA. FRET detection of cellular alpha4-integrin conformational activation. Biophysical Journal. 85: 3951-62. PMID 14645084 DOI: 10.1016/S0006-3495(03)74809-7 |
0.699 |
|
| 2003 |
Simons PC, Shi M, Foutz T, Cimino DF, Lewis J, Buranda T, Lim WK, Neubig RR, McIntire WE, Garrison J, Prossnitz E, Sklar LA. Ligand-receptor-G-protein molecular assemblies on beads for mechanistic studies and screening by flow cytometry. Molecular Pharmacology. 64: 1227-38. PMID 14573773 DOI: 10.1124/Mol.64.5.1227 |
0.743 |
|
| 2003 |
Chigaev A, Zwartz G, Graves SW, Dwyer DC, Tsuji H, Foutz TD, Edwards BS, Prossnitz ER, Larson RS, Sklar LA. Alpha4beta1 integrin affinity changes govern cell adhesion. The Journal of Biological Chemistry. 278: 38174-82. PMID 12844491 DOI: 10.1074/Jbc.M210472200 |
0.694 |
|
| 2003 |
Shi M, Bennett TA, Cimino DF, Maestas DC, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Functional capabilities of an N-formyl peptide receptor-G(alpha)(i)(2) fusion protein: assemblies with G proteins and arrestins. Biochemistry. 42: 7283-93. PMID 12809484 DOI: 10.1021/Bi0341657 |
0.733 |
|
| 2003 |
Waller A, Simons P, Prossnitz ER, Edwards BS, Sklar LA. High throughput screening of G-protein coupled receptors via flow cytometry. Combinatorial Chemistry & High Throughput Screening. 6: 389-97. PMID 12769683 DOI: 10.2174/138620703106298482 |
0.744 |
|
| 2003 |
Key TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity. The Journal of Biological Chemistry. 278: 4041-7. PMID 12424254 DOI: 10.1074/Jbc.M204687200 |
0.816 |
|
| 2002 |
Posner RG, Savage PB, Peters AS, Macias A, DelGado J, Zwartz G, Sklar LA, Hlavacek WS. A quantitative approach for studying IgE-FcepsilonRI aggregation. Molecular Immunology. 38: 1221-8. PMID 12217387 DOI: 10.1016/S0161-5890(02)00067-6 |
0.422 |
|
| 2002 |
Kepley CL, Andrews RP, Brown DC, Chigaev A, Sklar LA, Oliver JM, Larson RS. Regulation of human basophil adhesion to endothelium under flow conditions: Different very late antigen 4 regulation on umbilical cord blood-derived and peripheral blood basophils. The Journal of Allergy and Clinical Immunology. 110: 469-75. PMID 12209096 DOI: 10.1067/Mai.2002.126462 |
0.357 |
|
| 2002 |
Jackson WC, Bennett TA, Edwards BS, Prossnitz E, Lopez GP, Sklar LA. Performance of in-line microfluidic mixers in laminar flow for high-throughput flow cytometry. Biotechniques. 33: 220-6. PMID 12139249 DOI: 10.2144/02331Dd06 |
0.662 |
|
| 2002 |
Sklar LA, Edwards BS, Graves SW, Nolan JP, Prossnitz ER. Flow cytometric analysis of ligand-receptor interactions and molecular assemblies. Annual Review of Biophysics and Biomolecular Structure. 31: 97-119. PMID 11988464 DOI: 10.1146/Annurev.Biophys.31.082901.134406 |
0.708 |
|
| 2002 |
Buranda T, Huang J, Perez-Luna VH, Schreyer B, Sklar LA, Lopez GP. Biomolecular recognition on well-characterized beads packed in microfluidic channels. Analytical Chemistry. 74: 1149-56. PMID 11924977 DOI: 10.1021/Ac0109624 |
0.393 |
|
| 2002 |
Jackson WC, Kuckuck F, Edwards BS, Mammoli A, Gallegos CM, Lopez GP, Buranda T, Sklar LA. Mixing small volumes for continuous high-throughput flow cytometry: performance of a mixing Y and peristaltic sample delivery. Cytometry. 47: 183-91. PMID 11891723 DOI: 10.1002/Cyto.10067 |
0.302 |
|
| 2002 |
Graves SW, Nolan JP, Jett JH, Martin JC, Sklar LA. Nozzle design parameters and their effects on rapid sample delivery in flow cytometry. Cytometry. 47: 127-37. PMID 11813203 DOI: 10.1002/Cyto.10056 |
0.318 |
|
| 2002 |
Potter RM, Key TA, Gurevich VV, Sklar LA, Prossnitz ER. Arrestin variants display differential binding characteristics for the phosphorylated N-formyl peptide receptor carboxyl terminus. The Journal of Biological Chemistry. 277: 8970-8. PMID 11777932 DOI: 10.1074/Jbc.M111086200 |
0.809 |
|
| 2002 |
Pérez-Luna VH, Yang S, Rabinovich EM, Buranda T, Sklar LA, Hampton PD, López GP. Fluorescence biosensing strategy based on energy transfer between fluorescently labeled receptors and a metallic surface. Biosensors & Bioelectronics. 17: 71-8. PMID 11742737 DOI: 10.1016/S0956-5663(01)00260-3 |
0.353 |
|
| 2002 |
Nolan JP, Sklar LA. Suspension array technology: evolution of the flat-array paradigm. Trends in Biotechnology. 20: 9-12. PMID 11742671 DOI: 10.1016/S0167-7799(01)01844-3 |
0.342 |
|
| 2001 |
Edwards BS, Sklar LA. Plug flow cytometry. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 1.17. PMID 18770666 DOI: 10.1002/0471142956.Cy0117S17 |
0.33 |
|
| 2001 |
Buranda T, Lopez GP, Simons P, Pastuszyn A, Sklar LA. Detection of epitope-tagged proteins in flow cytometry: fluorescence resonance energy transfer-based assays on beads with femtomole resolution. Analytical Biochemistry. 298: 151-62. PMID 11700971 DOI: 10.1006/Abio.2001.5363 |
0.368 |
|
| 2001 |
Edwards BS, Kuckuck FW, Prossnitz ER, Ransom JT, Sklar LA. HTPS flow cytometry: a novel platform for automated high throughput drug discovery and characterization. Journal of Biomolecular Screening. 6: 83-90. PMID 11689102 DOI: 10.1177/108705710100600204 |
0.711 |
|
| 2001 |
Chigaev A, Blenc AM, Braaten JV, Kumaraswamy N, Kepley CL, Andrews RP, Oliver JM, Edwards BS, Prossnitz ER, Larson RS, Sklar LA. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. The Journal of Biological Chemistry. 276: 48670-8. PMID 11641394 DOI: 10.1074/Jbc.M103194200 |
0.729 |
|
| 2001 |
Bennett TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Partial phosphorylation of the N-formyl peptide receptor inhibits G protein association independent of arrestin binding. The Journal of Biological Chemistry. 276: 49195-203. PMID 11602585 DOI: 10.1074/Jbc.M106414200 |
0.725 |
|
| 2001 |
Key TA, Bennett TA, Foutz TD, Gurevich VV, Sklar LA, Prossnitz ER. Regulation of formyl peptide receptor agonist affinity by reconstitution with arrestins and heterotrimeric G proteins. The Journal of Biological Chemistry. 276: 49204-12. PMID 11598142 DOI: 10.1074/Jbc.M109475200 |
0.828 |
|
| 2001 |
Kuckuck FW, Edwards BS, Sklar LA. High throughput flow cytometry. Cytometry. 44: 83-90. PMID 11309812 DOI: 10.1002/1097-0320(20010501)44:1<83::Aid-Cyto1085>3.0.Co;2-O |
0.307 |
|
| 2001 |
Bennett TA, Key TA, Gurevich VV, Neubig R, Prossnitz ER, Sklar LA. Real-time analysis of G protein-coupled receptor reconstitution in a solubilized system. The Journal of Biological Chemistry. 276: 22453-60. PMID 11309376 DOI: 10.1074/Jbc.M009679200 |
0.826 |
|
| 2001 |
Edwards BS, Kuckuck FW, Prossnitz ER, Okun A, Ransom JT, Sklar LA. Plug flow cytometry extends analytical capabilities in cell adhesion and receptor pharmacology. Cytometry. 43: 211-6. PMID 11170109 DOI: 10.1002/1097-0320(20010301)43:3<211::Aid-Cyto1052>3.0.Co;2-3 |
0.677 |
|
| 2000 |
Burchiel SW, Edwards BS, Kuckuck FW, Lauer FT, Prossnitz ER, Ransom JT, Sklar LA. Analysis of free intracellular calcium by flow cytometry: multiparameter and pharmacologic applications. Methods (San Diego, Calif.). 21: 221-30. PMID 10873476 DOI: 10.1006/Meth.2000.1002 |
0.655 |
|
| 2000 |
Edwards BS, Curry MS, Tsuji H, Brown D, Larson RS, Sklar LA. Expression of P-selectin at low site density promotes selective attachment of eosinophils over neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 165: 404-10. PMID 10861078 DOI: 10.4049/Jimmunol.165.1.404 |
0.305 |
|
| 2000 |
Sklar LA, Vilven J, Lynam E, Neldon D, Bennett TA, Prossnitz E. Solubilization and display of G protein-coupled receptors on beads for real-time fluorescence and flow cytometric analysis. Biotechniques. 28: 976-80, 982-5. PMID 10818705 DOI: 10.2144/00285Rr03 |
0.749 |
|
| 1999 |
Seamer LC, Kuckuck F, Sklar LA. Sheath fluid control to permit stable flow in rapid mix flow cytometry. Cytometry. 35: 75-9. PMID 10554183 DOI: 10.1002/(Sici)1097-0320(19990101)35:1<75::Aid-Cyto10>3.0.Co;2-Y |
0.322 |
|
| 1999 |
Buranda T, Lopez GP, Keij J, Harris R, Sklar LA. Peptides, antibodies, and FRET on beads in flow cytometry: A model system using fluoresceinated and biotinylated beta-endorphin. Cytometry. 37: 21-31. PMID 10451503 DOI: 10.1002/(Sici)1097-0320(19990901)37:1<21::Aid-Cyto3>3.0.Co;2-G |
0.353 |
|
| 1999 |
Nolan JP, Lauer S, Prossnitz ER, Sklar LA. Flow cytometry: a versatile tool for all phases of drug discovery. Drug Discovery Today. 4: 173-180. PMID 10322276 DOI: 10.1016/S1359-6446(99)01320-3 |
0.655 |
|
| 1999 |
Gilbert TL, Prossnitz ER, Sklar LA. The uncoupled state of the human formyl peptide receptor. Journal of Receptor and Signal Transduction Research. 19: 327-40. PMID 10071768 DOI: 10.3109/10799899909036655 |
0.818 |
|
| 1999 |
Prossnitz ER, Gilbert TL, Chiang S, Campbell JJ, Qin S, Newman W, Sklar LA, Ye RD. Multiple activation steps of the N-formyl peptide receptor. Biochemistry. 38: 2240-7. PMID 10029516 DOI: 10.1021/Bi982274T |
0.822 |
|
| 1999 |
Buranda T, Jones GM, Nolan JP, Keij J, Lopez GP, Sklar LA. Ligand Receptor Dynamics at Streptavidin-Coated Particle Surfaces: A Flow Cytometric and Spectrofluorimetric Study The Journal of Physical Chemistry B. 103: 3399-3410. DOI: 10.1021/Jp983842H |
0.386 |
|
| 1998 |
Lynam E, Sklar LA, Taylor AD, Neelamegham S, Edwards BS, Smith CW, Simon SI. Beta2-integrins mediate stable adhesion in collisional interactions between neutrophils and ICAM-1-expressing cells. Journal of Leukocyte Biology. 64: 622-30. PMID 9823767 DOI: 10.1002/Jlb.64.5.622 |
0.362 |
|
| 1998 |
Nolan JP, Sklar LA. The emergence of flow cytometry for sensitive, real-time measurements of molecular interactions. Nature Biotechnology. 16: 633-8. PMID 9661195 DOI: 10.1038/Nbt0798-633 |
0.308 |
|
| 1998 |
Vilven JC, Domalewski M, Prossnitz ER, Ye RD, Muthukumaraswamy N, Harris RB, Freer RJ, Sklar LA. Strategies for positioning fluorescent probes and crosslinkers on formyl peptide ligands. Journal of Receptor and Signal Transduction Research. 18: 187-221. PMID 9651885 DOI: 10.3109/10799899809047744 |
0.698 |
|
| 1998 |
Sklar LA, Seamer LC, Kuckuck F, Posner RG, Prossnitz E, Edwards B, Nolan JP. Sample handling for kinetics and molecular assembly in flow cytometry Proceedings of Spie - the International Society For Optical Engineering. 3256: 144-153. DOI: 10.1117/12.307057 |
0.611 |
|
| 1997 |
Hall AL, Wilson BS, Pfeiffer JR, Oliver JM, Sklar LA. Relationship of ligand-receptor dynamics to actin polymerization in RBL- 2H3 cells transfected with the human formyl peptide receptor Journal of Leukocyte Biology. 62: 535-546. PMID 9335325 DOI: 10.1002/Jlb.62.4.535 |
0.442 |
|
| 1997 |
Lee RJ, Lujan DE, Hall AL, Sklar LA, Wilson BS, Oliver JM. Cooperation between the FcεR1 and formyl peptide receptor signaling pathways in RBL(FPR) cells: The contribution of receptor-specific Ca2+ mobilization responses Biochemical and Biophysical Research Communications. 235: 812-819. PMID 9207244 DOI: 10.1006/Bbrc.1997.6874 |
0.327 |
|
| 1997 |
Domalewski MD, Guyer DA, Freer RJ, Muthukumaraswamy N, Sklar LA. Fixation traps formyl peptide receptors in high and low affinity forms that can be regulated by GTP[S] in the absence of ligand. Journal of Receptor and Signal Transduction Research. 16: 59-75. PMID 8771531 DOI: 10.3109/10799899609039941 |
0.485 |
|
| 1996 |
Deka C, Lehnert BE, Lehnert NM, Jones GM, Sklar LA, Steinkamp JA. Analysis of fluorescence lifetime and quenching of FITC-conjugated antibodies on cells by phase-sensitive flow cytometry. Cytometry. 25: 271-9. PMID 8914824 DOI: 10.1002/(Sici)1097-0320(19961101)25:3<271::Aid-Cyto8>3.0.Co;2-I |
0.324 |
|
| 1995 |
Nolan JP, Posner RG, Martin JC, Habbersett R, Sklar LA. A rapid mix flow cytometer with subsecond kinetic resolution. Cytometry. 21: 223-9. PMID 8582244 DOI: 10.1002/Cyto.990210302 |
0.363 |
|
| 1995 |
Bennett TA, Schammel CM, Lynam EB, Guyer DA, Mellors A, Edwards B, Rogelj S, Sklar LA. Evidence for a third component in neutrophil aggregation: potential roles of O-linked glycoproteins as L-selectin counter-structures. Journal of Leukocyte Biology. 58: 510-8. PMID 7595051 DOI: 10.1002/Jlb.58.5.510 |
0.316 |
|
| 1993 |
Fay SP, Domalewski MD, Sklar LA. Evidence for protonation in the human neutrophil formyl peptide receptor binding pocket. Biochemistry. 32: 1627-31. PMID 8431442 DOI: 10.1021/Bi00057A029 |
0.368 |
|
| 1993 |
Brandt MM, Lynam E, Sklar LA. Methylprednisolone inhibits three classes of neutrophil receptors in human blood in vitro. The Journal of Surgical Research. 55: 632-9. PMID 8246497 DOI: 10.1006/Jsre.1993.1196 |
0.45 |
|
| 1993 |
Chambers JD, Simon SI, Berger EM, Sklar LA, Arfors KE. Endocytosis of beta 2 integrins by stimulated human neutrophils analyzed by flow cytometry. Journal of Leukocyte Biology. 53: 462-9. PMID 8097762 DOI: 10.1002/Jlb.53.4.462 |
0.32 |
|
| 1993 |
Simon S, Rochon Y, Lynam E, Smith C, Anderson D, Sklar L. Beta 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation [see comments] Blood. 82: 1097-1106. DOI: 10.1182/Blood.V82.4.1097.1097 |
0.318 |
|
| 1993 |
Jett JH, Cram LS, Keller RA, Martin JC, Saunders GC, Sklar LA, Steinkamp JA. Ultrasensitive flow cytometric analyses Proceedings of Spie - the International Society For Optical Engineering. 1895: 123-129. DOI: 10.1117/12.146722 |
0.311 |
|
| 1992 |
Mueller H, Montoya B, Sklar LA. Reversal of inhibitory pathways in neutrophils by protein kinase antagonists: a rational approach to the restoration of depressed cell function? Journal of Leukocyte Biology. 52: 400-6. PMID 1328441 DOI: 10.1002/Jlb.52.4.400 |
0.329 |
|
| 1991 |
Fay SP, Posner RG, Swann WN, Sklar LA. Real-time analysis of the assembly of ligand, receptor, and G protein by quantitative fluorescence flow cytometry. Biochemistry. 30: 5066-75. PMID 1645188 DOI: 10.1021/Bi00234A033 |
0.46 |
|
| 1990 |
Sklar LA, Fay SP, Seligmann BE, Freer RJ, Muthukumaraswamy N, Mueller H. Fluorescence analysis of the size of a binding pocket of a peptide receptor at natural abundance. Biochemistry. 29: 313-6. PMID 2105739 DOI: 10.1021/Bi00454A002 |
0.414 |
|
| 1989 |
Norgauer J, Just I, Aktories K, Sklar LA. Influence of botulinum C2 toxin on F-actin and N-formyl peptide receptor dynamics in human neutrophils. The Journal of Cell Biology. 109: 1133-40. PMID 2768337 DOI: 10.1083/Jcb.109.3.1133 |
0.319 |
|
| 1989 |
Mueller H, Sklar LA. Coupling of antagonistic signalling pathways in modulation of neutrophil function. Journal of Cellular Biochemistry. 40: 287-94. PMID 2550487 DOI: 10.1002/Jcb.240400305 |
0.415 |
|
| 1988 |
Traynor-Kaplan AE, Harris AL, Thompson BL, Taylor P, Sklar LA. An inositol tetrakisphosphate-containing phospholipid in activated neutrophils. Nature. 334: 353-6. PMID 3393226 DOI: 10.1038/334353A0 |
0.317 |
|
| 1988 |
Omann GM, Sklar LA. Response of neutrophils to stimulus infusion: Differential sensitivity of cytoskeletal activation and oxidant production Journal of Cell Biology. 107: 951-958. PMID 2843551 DOI: 10.1083/Jcb.107.3.951 |
0.373 |
|
| 1986 |
Sklar LA. Ligand-receptor dynamics and signal amplification in the neutrophil. Advances in Immunology. 39: 95-143. PMID 3024470 DOI: 10.1016/S0065-2776(08)60349-1 |
0.422 |
|
| 1985 |
Sklar LA, Omann GM, Painter RG. Relationship of actin polymerization and depolymerization to light scattering in human neutrophils: dependence on receptor occupancy and intracellular Ca++. The Journal of Cell Biology. 101: 1161-6. PMID 4040917 DOI: 10.1083/Jcb.101.3.1161 |
0.356 |
|
| 1985 |
Jesaitis AJ, Tolley JO, Painter RG, Sklar LA, Cochrane CG. Membrane-cytoskeleton interactions and the regulation of chemotactic peptide-induced activation of human granulocytes: The effects of dihydrocytochalasin B Journal of Cellular Biochemistry. 27: 241-253. PMID 3838753 DOI: 10.1002/Jcb.240270306 |
0.431 |
|
| 1984 |
Jesaitis AJ, Naemura JR, Sklar LA, Cochrane CG, Painter RG. Rapid modulation of N-formyl chemotactic peptide receptors on the surface of human granulocytes: Formation of high-affinity ligand-receptor complexes in transient association with cytoskeleton Journal of Cell Biology. 98: 1378-1387. PMID 6325470 DOI: 10.1083/Jcb.98.4.1378 |
0.398 |
|
| 1984 |
Hyslop PA, Oades ZG, Jesaitis AJ, Painter RG, Cochrane CG, Sklar LA. Evidence for N-formyl chemotactic peptide-stimulated GTPase activity in human neutrophil homogenates Febs Letters. 166: 165-169. PMID 6141069 DOI: 10.1016/0014-5793(84)80065-4 |
0.348 |
|
| 1984 |
Sklar LA, Jesaitis AJ, Painter RG. The neutrophil N-formyl peptide receptor: dynamics of ligand-receptor interactions and their relationship to cellular responses Contemporary Topics in Immunobiology. 14: 29-82. PMID 6101244 DOI: 10.1007/978-1-4757-4862-8_2 |
0.387 |
|
| 1983 |
Finney DA, Sklar LA. Ligand/receptor internalization: a kinetic, flow cytometric analysis of the internalization of N-formyl peptides by human neutrophils. Cytometry. 4: 54-60. PMID 6617394 DOI: 10.1002/Cyto.990040108 |
0.426 |
|
| 1983 |
Sklar LA, Finney DA. Analysis of ligand-receptor interactions with the fluorescence activated cell sorter. Cytometry. 3: 161-5. PMID 6293787 DOI: 10.1002/Cyto.990030304 |
0.442 |
|
| 1982 |
Painter RG, Schmitt M, Jesaitis AJ, Sklar LA, Preissner K, Cochrane CG. Photoaffinity labeling of the N-formyl peptide receptor of human polymorphonuclear leukocytes Journal of Cellular Biochemistry. 20: 203-214. PMID 6302117 DOI: 10.1002/Jcb.240200211 |
0.461 |
|
| 1982 |
Sklar LA, Jesaitis AJ, Painter RG, Cochrane CG. Ligand/receptor internalization: A spectroscopic analysis and a comparison of ligand binding, cellular response, and internalization by human neutrophils Journal of Cellular Biochemistry. 20: 193-202. PMID 6302116 DOI: 10.1002/Jcb.240200210 |
0.44 |
|
| 1982 |
Jesaitis AJ, Naemura JR, Painter RG, Schmitt M, Sklar LA, Cochrane CG. The fate of the N-formyl-chemotactic peptide receptor in stimulated human granulocytes: Subcellular fractionation studies Journal of Cellular Biochemistry. 20: 177-191. PMID 6302115 DOI: 10.1002/Jcb.240200209 |
0.366 |
|
| 1981 |
Sklar LA, Oades ZG, Jesaitis AJ, Painter RG, Cochrane CG. Fluoresceinated chemotactic peptide and high-affinity antifluorescein antibody as a probe of the temporal characteristics of neutrophil stimulation Proceedings of the National Academy of Sciences of the United States of America. 78: 7540-7544. PMID 7038681 DOI: 10.1073/Pnas.78.12.7540 |
0.342 |
|
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