Year |
Citation |
Score |
2024 |
Núñez FJ, Banerjee K, Mujeeb AA, Mauser A, Tronrud CE, Zhu Z, Taher A, Kadiyala P, Carney SV, Garcia-Fabiani MB, Comba A, Alghamri MS, McClellan BL, Faisal SM, Nwosu ZC, ... ... Ljungman M, et al. Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation. Biorxiv : the Preprint Server For Biology. PMID 38559270 DOI: 10.1101/2024.03.08.584091 |
0.321 |
|
2023 |
Melnick AF, Mullin C, Lin K, McCarter AC, Liang S, Liu YE, Wang Q, Jerome NA, Choe E, Kunnath N, Bodanapu G, Akter F, Magnuson B, Kumar S, Lombard DB, ... ... Ljungman M, et al. Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress. Blood. PMID 37616559 DOI: 10.1182/blood.2023020144 |
0.326 |
|
2022 |
Magnuson B, Bedi K, Narayanan IV, Bartkowiak B, Blinkiewicz H, Paulsen MT, Greenleaf A, Ljungman M. CDK12 regulates co-transcriptional splicing and RNA turnover in human cells. Iscience. 25: 105030. PMID 36111258 DOI: 10.1016/j.isci.2022.105030 |
0.384 |
|
2022 |
Ljungman M. Transcription and genome integrity. Dna Repair. 118: 103373. PMID 35914488 DOI: 10.1016/j.dnarep.2022.103373 |
0.346 |
|
2021 |
Park SH, Bennett-Baker P, Ahmed S, Arlt MF, Ljungman M, Glover TW, Wilson TE. Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay. Nucleic Acids Research. PMID 34181717 DOI: 10.1093/nar/gkab559 |
0.31 |
|
2021 |
Bouvier D, Ferrand J, Chevallier O, Paulsen MT, Ljungman M, Polo SE. Dissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA. Nature Communications. 12: 3835. PMID 34158510 DOI: 10.1038/s41467-021-24153-1 |
0.316 |
|
2021 |
van der Weegen Y, de Lint K, van den Heuvel D, Nakazawa Y, Mevissen TET, van Schie JJM, San Martin Alonso M, Boer DEC, González-Prieto R, Narayanan IV, Klaassen NHM, Wondergem AP, Roohollahi K, Dorsman JC, Hara Y, ... ... Ljungman M, et al. ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation. Nature Cell Biology. 23: 595-607. PMID 34108663 DOI: 10.1038/s41556-021-00688-9 |
0.326 |
|
2021 |
van den Heuvel D, Spruijt CG, González-Prieto R, Kragten A, Paulsen MT, Zhou D, Wu H, Apelt K, van der Weegen Y, Yang K, Dijk M, Daxinger L, Marteijn JA, Vertegaal ACO, Ljungman M, et al. A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair. Nature Communications. 12: 1342. PMID 33637760 DOI: 10.1038/s41467-021-21520-w |
0.356 |
|
2020 |
Wu X, Niculite CM, Preda MB, Rossi A, Tebaldi T, Butoi E, White MK, Tudoran OM, Petrusca DN, Jannasch AS, Bone WP, Zong X, Fang F, Burlacu A, Paulsen MT, ... ... Ljungman M, et al. Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS. Nature Communications. 11: 4755. PMID 32958772 DOI: 10.1038/S41467-020-18411-X |
0.349 |
|
2020 |
Jalihal AP, Pitchiaya S, Xiao L, Bawa P, Jiang X, Bedi K, Parolia A, Cieslik M, Ljungman M, Chinnaiyan AM, Walter NG. Multivalent Proteins Rapidly and Reversibly Phase-Separate upon Osmotic Cell Volume Change. Molecular Cell. PMID 32857953 DOI: 10.1016/J.Molcel.2020.08.004 |
0.344 |
|
2020 |
Shergalis A, Xue D, Gharbia FZ, Driks H, Shrestha B, Tanweer A, Cromer K, Ljungman M, Neamati N. Characterization of aminobenzylphenols as protein disulfide isomerase inhibitors in glioblastoma cell lines. Journal of Medicinal Chemistry. PMID 32830969 DOI: 10.1021/Acs.Jmedchem.0C00728 |
0.35 |
|
2020 |
Hu S, Sechi M, Singh PK, Dai L, McCann S, Sun D, Ljungman M, Neamati N. A Novel Redox Modulator Induces a GPX4-mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. Journal of Medicinal Chemistry. PMID 32809827 DOI: 10.1021/Acs.Jmedchem.0C01016 |
0.373 |
|
2020 |
Chen W, Hu S, Mao S, Xu Y, Guo H, Li H, Paulsen MT, Chen X, Ljungman M, Neamati N. Discovery of Potential Mitochondrial Transcription Inhibitors as Anticancer Agents by Transcriptomic Profiling. Chemmedchem. PMID 32748543 DOI: 10.1002/Cmdc.202000494 |
0.342 |
|
2020 |
Liu Y, Awadia S, Delaney A, Sitto M, Engelke C, Patel H, Calcaterra A, Zelenka-Wang S, Lee H, Contessa J, Neamati N, Ljungman M, Lawrence TS, Morgan MA, Rehemtulla A. UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer. Translational Oncology. 13: 100834. PMID 32688248 DOI: 10.1016/J.Tranon.2020.100834 |
0.432 |
|
2020 |
Sarni D, Sasaki T, Irony Tur-Sinai M, Miron K, Rivera-Mulia JC, Magnuson B, Ljungman M, Gilbert DM, Kerem B. 3D genome organization contributes to genome instability at fragile sites. Nature Communications. 11: 3613. PMID 32680994 DOI: 10.1038/S41467-020-17448-2 |
0.339 |
|
2020 |
Xu Y, Bankhead A, Tian X, Tang J, Ljungman M, Neamati N. Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor. Cancer Research. PMID 32571799 DOI: 10.1158/0008-5472.Can-20-0530 |
0.407 |
|
2020 |
Lu T, Tang J, Shrestha B, Heath BR, Hong L, Lei YL, Ljungman M, Neamati N. Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer. Theranostics. 10: 6959-6976. PMID 32550915 DOI: 10.7150/Thno.41792 |
0.455 |
|
2020 |
Frey TR, Brathwaite J, Li X, Burgula S, Akinyemi IA, Agarwal S, Burton EM, Ljungman M, McIntosh MT, Bhaduri-McIntosh S. Nascent transcriptomics reveal cellular pro-lytic factors upregulated upstream of the latency-to-lytic switch protein of Epstein-Barr virus. Journal of Virology. PMID 31941784 DOI: 10.1128/Jvi.01966-19 |
0.379 |
|
2019 |
Lu T, Bankhead A, Ljungman M, Neamati N. Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3. Theranostics. 9: 5478-5496. PMID 31534498 DOI: 10.7150/Thno.33444 |
0.325 |
|
2019 |
Ljungman M, Parks L, Hulbatte R, Bedi K. The role of H3K79 methylation in transcription and the DNA damage response. Mutation Research. 780: 48-54. PMID 31395348 DOI: 10.1016/J.Mrrev.2017.11.001 |
0.419 |
|
2019 |
Xu S, Liu Y, Yang K, Wang H, Shergalis A, Kyani A, Bankhead A, Tamura S, Yang S, Wang X, Wang CC, Rehemtulla A, Ljungman M, Neamati N. Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes. Theranostics. 9: 2282-2298. PMID 31149044 DOI: 10.7150/Thno.30621 |
0.473 |
|
2019 |
Wang L, Yang H, Zamperone A, Diolaiti D, Palmbos PL, Abel EV, Purohit V, Dolgalev I, Rhim AD, Ljungman M, Hadju CH, Halbrook CJ, Bar-Sagi D, di Magliano MP, Crawford HC, et al. ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis. Genes & Development. PMID 31048544 DOI: 10.1101/Gad.323303.118 |
0.333 |
|
2019 |
Liu Y, Ji W, Shergalis A, Xu J, Delaney AM, Calcaterra A, Pal A, Ljungman M, Neamati N, Rehemtulla A. Activation of the unfolded protein response via inhibition of protein disulfide isomerase decreases the capacity for DNA repair to sensitize glioblastoma to radiotherapy. Cancer Research. PMID 30996048 DOI: 10.1158/0008-5472.Can-18-2540 |
0.456 |
|
2019 |
Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, ... Ljungman M, et al. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Science Translational Medicine. 11. PMID 30760578 DOI: 10.1126/Scitranslmed.Aaq1427 |
0.355 |
|
2019 |
Yang S, Shergalis A, Lu D, Kyani A, Lu Z, Ljungman M, Neamati N. Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors. Journal of Medicinal Chemistry. PMID 30759340 DOI: 10.1021/Acs.Jmedchem.8B01951 |
0.368 |
|
2019 |
Kim HS, Lu S, Cao Y, Yi Z, Jeyarajan S, Zhao L, Bedi K, Narayanan IV, Paulsen MT, Ljungman M, Shi J. Abstract C28: KMT2D mediates TGF-β-induced epithelial-to-mesenchymal transition to promote more aggressive pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C28 |
0.395 |
|
2019 |
Jeyarajan S, Yi Z, Wei S, Lu S, Kim H, Paulsen M, Bedi K, Ljungman M, Shi J. Abstract C22: Loss of KDM6A promotes pancreatic cancer progression by upregulating epithelial-mesenchymal transition pathway Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C22 |
0.403 |
|
2018 |
Sima J, Chakraborty A, Dileep V, Michalski M, Klein KN, Holcomb NP, Turner JL, Paulsen MT, Rivera-Mulia JC, Trevilla-Garcia C, Bartlett DA, Zhao PA, Washburn BK, Nora EP, Kraft K, ... ... Ljungman M, et al. Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication. Cell. PMID 30595451 DOI: 10.1016/J.Cell.2018.11.036 |
0.313 |
|
2018 |
Hu S, Jin Y, Liu Y, Ljungman M, Neamati N. Synthesis and mechanistic studies of quinolin-chlorobenzothioate derivatives with proteasome inhibitory activity in pancreatic cancer cell lines. European Journal of Medicinal Chemistry. 158: 884-895. PMID 30253345 DOI: 10.1016/J.Ejmech.2018.09.037 |
0.438 |
|
2018 |
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, et al. HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties. Elife. 7. PMID 30074477 DOI: 10.7554/Elife.33947 |
0.424 |
|
2018 |
Zhang Y, Pitchiaya S, Cieślik M, Niknafs YS, Tien JC, Hosono Y, Iyer MK, Yazdani S, Subramaniam S, Shukla SK, Jiang X, Wang L, Liu TY, Uhl M, Gawronski AR, ... ... Ljungman M, et al. Analysis of the androgen receptor-regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression. Nature Genetics. PMID 29808028 DOI: 10.1038/S41588-018-0120-1 |
0.317 |
|
2018 |
Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, et al. Menin regulates the serine biosynthetic pathway in Ewing sarcoma. The Journal of Pathology. PMID 29672864 DOI: 10.1002/Path.5085 |
0.426 |
|
2018 |
Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Daylan AEC, Kovalenko I, Lee HJ, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, ... ... Ljungman M, et al. Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma. Jci Insight. 3. PMID 29367463 DOI: 10.1172/Jci.Insight.97422 |
0.374 |
|
2018 |
Kuang Y, Sechi M, Nurra S, Ljungman M, Neamati N. Design and Synthesis of Novel Reactive Oxygen Species Inducers for the Treatment of Pancreatic Ductal Adenocarcinoma. Journal of Medicinal Chemistry. PMID 29328656 DOI: 10.1021/Acs.Jmedchem.7B01463 |
0.39 |
|
2018 |
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, et al. Author response: HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties Elife. DOI: 10.7554/Elife.33947.042 |
0.344 |
|
2018 |
Zhang Y, Pitchiaya S, Cieślik M, Niknafs YS, Tien JC, Hosono Y, Wang L, Qiao Y, Cao X, Ljungman M, Jiang H, Mehra R, Guo S, Malik R, Chinnaiyan AM. Abstract 2458: The androgen receptor-regulated lncRNA landscape reveals a role for ARlnc1 in prostate cancer progression Cancer Research. 78: 2458-2458. DOI: 10.1158/1538-7445.Am2018-2458 |
0.313 |
|
2018 |
Nunez F, Mendez F, Kadiyala P, Alghamri M, Carney S, Ljungman M, Qin T, Sartor M, Venneti S, Lyssiotis C, Costello J, Herting C, Hambardzumyan D, Figueroa M, Lowenstein P, et al. GENE-35. IDH1-R132H INDUCES AN EPIGENETIC REPROGRAMMING IN GLIOMA IMPACTING MEDIAN SURVIVAL, DNA-DAMAGE RESPONSE AND RADIO-SENSITIVITY Neuro-Oncology. 20: vi111-vi111. DOI: 10.1093/Neuonc/Noy148.461 |
0.369 |
|
2017 |
Kyani A, Tamura S, Yang S, Shergalis A, Samanta S, Kuang Y, Ljungman M, Neamati N. Discovery and Mechanistic Elucidation of a Class of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma. Chemmedchem. PMID 29235250 DOI: 10.1002/Cmdc.201700629 |
0.383 |
|
2017 |
Galbán S, Apfelbaum AA, Espinoza C, Heist K, Haley H, Bedi K, Ljungman M, Galbán CJ, Luker GD, Van Dort M, Ross BD. A bifunctional MAPK/PI3K antagonist for inhibition of tumor growth and metastasis. Molecular Cancer Therapeutics. PMID 28775144 DOI: 10.1158/1535-7163.Mct-17-0207 |
0.344 |
|
2017 |
Iannelli F, Galbiati A, Capozzo I, Nguyen Q, Magnuson B, Michelini F, D'Alessandro G, Cabrini M, Roncador M, Francia S, Crosetto N, Ljungman M, Carninci P, d'Adda di Fagagna F. A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks. Nature Communications. 8: 15656. PMID 28561034 DOI: 10.1038/Ncomms15656 |
0.441 |
|
2017 |
Frank SB, Berger PL, Ljungman M, Miranti CK. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC. Journal of Cell Science. PMID 28446540 DOI: 10.1242/jcs.197152 |
0.434 |
|
2017 |
Venkata Narayanan I, Paulsen MT, Bedi K, Berg N, Ljungman EA, Francia S, Veloso A, Magnuson B, di Fagagna FD, Wilson TE, Ljungman M. Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53. Scientific Reports. 7: 43598. PMID 28256581 DOI: 10.1038/Srep43598 |
0.488 |
|
2017 |
Zhang H, Gan H, Wang Z, Lee JH, Zhou H, Ordog T, Wold MS, Ljungman M, Zhang Z. RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells. Molecular Cell. 65: 272-284. PMID 28107649 DOI: 10.1016/J.Molcel.2016.11.030 |
0.361 |
|
2017 |
Kirkconnell KS, Magnuson B, Paulsen MT, Lu B, Bedi K, Ljungman M. Gene length as a biological timer to establish temporal transcriptional regulation. Cell Cycle (Georgetown, Tex.). 0. PMID 28055303 DOI: 10.1080/15384101.2016.1234550 |
0.335 |
|
2017 |
Svoboda LK, Teh SS, Sud S, Bankhead A, Magnuson B, Ljungman M, Lyssiotis C, Cierpicki T, Grembecka J, Lawlor ER. Abstract 5835: Oncogenic activation of the serine synthesis pathway by the scaffolding protein menin Cancer Research. 77: 5835-5835. DOI: 10.1158/1538-7445.Am2017-5835 |
0.307 |
|
2017 |
Nunez FJ, Mendez FM, Kadiyala P, Savelieff M, Koschmann C, Carney S, Patel R, Manawar S, Kamran N, Saxena M, Ljungman M, Qin T, Maureen S, Dzaman M, Vennneti S, et al. GENE-58. EPIGENETIC REPROGRAMMING IN MUTANT IDH1 GLIOMA IMPACTS MEDIAN SURVIVAL, ENHANCES DNA DAMAGE RESPONSE AND CONFERS RADIO-RESISTANCE Neuro-Oncology. 19: vi105-vi105. DOI: 10.1093/Neuonc/Nox168.430 |
0.345 |
|
2016 |
Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, et al. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance. Genes & Development. 30: 2669-2683. PMID 28087712 DOI: 10.1101/Gad.291021.116 |
0.355 |
|
2016 |
Ramkumar K, Samanta S, Kyani A, Yang S, Tamura S, Ziemke E, Stuckey JA, Li S, Chinnaswamy K, Otake H, Debnath B, Yarovenko V, Sebolt-Leopold JS, Ljungman M, Neamati N. Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor. Nature Communications. 7: 13084. PMID 27703239 DOI: 10.1038/Ncomms13084 |
0.402 |
|
2016 |
Magnuson B, Bedi K, Ljungman M. Genome stability versus transcript diversity. Dna Repair. PMID 27246512 DOI: 10.1016/J.Dnarep.2016.05.010 |
0.38 |
|
2016 |
Kirkconnell KS, Paulsen MT, Magnuson B, Bedi K, Ljungman M. Capturing the dynamic nascent transcriptome during acute cellular responses: The serum response. Biology Open. PMID 27230646 DOI: 10.1242/Bio.019323 |
0.386 |
|
2016 |
Bailey KM, Airkik M, Krook M, Magnuson B, Ljungman M, Lawlor E. Abstract B33: Plasticity of the Ewing sarcoma invasive program: How microenvironmental stresses alter the drivers and repressors of metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B33 |
0.38 |
|
2015 |
Magnuson B, Veloso A, Kirkconnell KS, Lima LC, Paulsen MT, Ljungman EA, Bedi K, Prasad J, Wilson TE, Ljungman M. Identifying transcription start sites and active enhancer elements using BruUV-seq. Scientific Reports. 5: 17978. PMID 26656874 DOI: 10.1038/Srep17978 |
0.424 |
|
2015 |
Yang H, Palmbos PL, Wang L, Kim EH, Ney GM, Liu C, Prasad J, Misek DE, Yu X, Ljungman M, Simeone DM. ATDC (Ataxia Telangectasia Group D Complementing) Promotes Radioresistance Through an Interaction with the RNF8 Ubiquitin Ligase. The Journal of Biological Chemistry. PMID 26381412 DOI: 10.1074/Jbc.M115.665489 |
0.434 |
|
2015 |
Lefkofsky HB, Veloso A, Ljungman M. Transcriptional and post-transcriptional regulation of nucleotide excision repair genes in human cells. Mutation Research. 776: 9-15. PMID 26255935 DOI: 10.1016/j.mrfmmm.2014.11.008 |
0.348 |
|
2015 |
Andrade-Lima LC, Veloso A, Ljungman M. Transcription Blockage Leads to New Beginnings. Biomolecules. 5: 1600-17. PMID 26197343 DOI: 10.3390/biom5031600 |
0.302 |
|
2015 |
Kuang Y, El-Khoueiry A, Taverna P, Ljungman M, Neamati N. Guadecitabine (SGI-110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin. Molecular Oncology. PMID 26160429 DOI: 10.1016/J.Molonc.2015.06.002 |
0.316 |
|
2015 |
Andrade-Lima LC, Veloso A, Paulsen MT, Menck CF, Ljungman M. DNA repair and recovery of RNA synthesis following exposure to ultraviolet light are delayed in long genes. Nucleic Acids Research. 43: 2744-56. PMID 25722371 DOI: 10.1093/Nar/Gkv148 |
0.412 |
|
2015 |
Wilson TE, Arlt MF, Park SH, Rajendran S, Paulsen M, Ljungman M, Glover TW. Large transcription units unify copy number variants and common fragile sites arising under replication stress. Genome Research. 25: 189-200. PMID 25373142 DOI: 10.1101/Gr.177121.114 |
0.375 |
|
2015 |
Kuang Y, El-Khoueiry A, Taverna P, Ljungman M, Neamati N. Abstract 2533: SGI-110 priming sensitizes hepatocellular carcinoma cells to oxaliplatin Cancer Research. 75: 2533-2533. DOI: 10.1158/1538-7445.Am2015-2533 |
0.361 |
|
2014 |
Svoboda LK, Harris A, Bailey NJ, Schwentner R, Tomazou E, von Levetzow C, Magnuson B, Ljungman M, Kovar H, Lawlor ER. Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs. Epigenetics : Official Journal of the Dna Methylation Society. 9: 1613-25. PMID 25625846 DOI: 10.4161/15592294.2014.988048 |
0.378 |
|
2014 |
Prensner JR, Chen W, Han S, Iyer MK, Cao Q, Kothari V, Evans JR, Knudsen KE, Paulsen MT, Ljungman M, Lawrence TS, Chinnaiyan AM, Feng FY. The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc. Neoplasia (New York, N.Y.). 16: 900-8. PMID 25425964 DOI: 10.1016/J.Neo.2014.09.001 |
0.306 |
|
2014 |
Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D, Leflein J, Davis M, Zhang M, Tang W, Hicks JK, Helchowski CM, Prasad J, Lawrence TS, Xu L, ... ... Ljungman M, et al. ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells. Cancer Research. 74: 1778-88. PMID 24469230 DOI: 10.1158/0008-5472.Can-13-2289 |
0.461 |
|
2014 |
Palmbos P, Wang L, Yang H, LeFlein J, Wilkinson JE, Kumar-Sinha C, Kunju LP, Daignault S, Wu X, Lotan Y, Liebert M, Ljungman M, Simeone D. Abstract B24: ATDC (Trim29) drives invasive bladder cancer formation Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B24 |
0.362 |
|
2014 |
Evans J, Prensner J, Chen W, Ljungman M, Lawrence T, Chinnaiyan A, Feng F. The Long Noncoding RNA PCAT-1 Promotes Prostate Cell Proliferation Through Posttranscriptional Stabilization of the cMyc Oncogene International Journal of Radiation Oncology*Biology*Physics. 90: S90. DOI: 10.1016/J.Ijrobp.2014.05.485 |
0.316 |
|
2013 |
Veloso A, Biewen B, Paulsen MT, Berg N, Carmo de Andrade Lima L, Prasad J, Bedi K, Magnuson B, Wilson TE, Ljungman M. Genome-wide transcriptional effects of the anti-cancer agent camptothecin. Plos One. 8: e78190. PMID 24194914 DOI: 10.1371/Journal.Pone.0078190 |
0.471 |
|
2013 |
Ray D, Shukla S, Allam US, Helman A, Ramanand SG, Tran L, Bassetti M, Krishnamurthy PM, Rumschlag M, Paulsen M, Sun L, Shanley TP, Ljungman M, Nyati MK, Zhang M, et al. Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages. Plos One. 8: e57290. PMID 23468959 DOI: 10.1371/Journal.Pone.0057290 |
0.312 |
|
2013 |
Paulsen MT, Veloso A, Prasad J, Bedi K, Ljungman EA, Tsan YC, Chang CW, Tarrier B, Washburn JG, Lyons R, Robinson DR, Kumar-Sinha C, Wilson TE, Ljungman M. Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response. Proceedings of the National Academy of Sciences of the United States of America. 110: 2240-5. PMID 23345452 DOI: 10.1073/Pnas.1219192110 |
0.382 |
|
2013 |
Palmbos P, Wang L, Yang H, Detzler T, Ney G, Hart J, Daignault-Newton S, Kunju LP, Kumar-Sinha C, Liebert M, Ljungman M, Simeone D. Abstract 313: ATDC drives bladder cancer formation by promoting methylation of the PTEN promoter and inhibition of p53 function. Cancer Research. 73: 313-313. DOI: 10.1158/1538-7445.Am2013-313 |
0.432 |
|
2012 |
Palmbos PL, Wang L, Yang H, Detzler T, Ney G, Lotan Y, Wilkerson JE, Kunju P, Ljungman M, Liebert M, Simeone DM. ATDC as a novel oncogene in bladder cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 269. PMID 27968252 DOI: 10.1200/Jco.2012.30.5_Suppl.269 |
0.329 |
|
2012 |
Palmbos PL, Wang L, Yang H, Detzler T, Ney G, Lotan Y, Healy PN, Daignault-Newton S, Kunju P, Kumar C, Ljungman M, Liebert M, Simeone DM. Novel oncogenic function of ATDC in bladder cancer. Journal of Clinical Oncology. 30: 4591-4591. DOI: 10.1200/Jco.2012.30.15_Suppl.4591 |
0.383 |
|
2012 |
Wang L, Lawrence T, Xu L, Canman C, Ljungman M, Simeone D, Yang H, Palmbos P, Ney G, Detzler TA, Coleman D, Davis M, Hicks K, Helchowski CM. Abstract A93: Radiation-induced phosphorylation of ATDC via ATM/MAPKAP kinase 2 signaling mediates radioresistance of pancreatic cancer cells. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A93 |
0.456 |
|
2012 |
Ljungman M, Paulsen M, Veloso A, Prasad J, Wilson T. Transcriptional inhibition by DNA damage as a trigger for cell death Toxicology Letters. 211: S8. DOI: 10.1016/J.TOXLET.2012.03.042 |
0.328 |
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2011 |
Fu J, Fang H, Paulsen M, Ljungman M, Kocarek TA, Runge-Morris M. Regulation of estrogen sulfotransferase expression by confluence of MCF10A breast epithelial cells: role of the aryl hydrocarbon receptor. The Journal of Pharmacology and Experimental Therapeutics. 339: 597-606. PMID 21828262 DOI: 10.1124/Jpet.111.185173 |
0.381 |
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2011 |
Wu J, Chen Y, Lu LY, Wu Y, Paulsen MT, Ljungman M, Ferguson DO, Yu X. Chfr and RNF8 synergistically regulate ATM activation. Nature Structural & Molecular Biology. 18: 761-8. PMID 21706008 DOI: 10.1038/Nsmb.2078 |
0.438 |
|
2010 |
Hall CL, Zhang H, Baile S, Ljungman M, Kuhstoss S, Keller ET. p21CIP-1/WAF-1 induction is required to inhibit prostate cancer growth elicited by deficient expression of the Wnt inhibitor Dickkopf-1. Cancer Research. 70: 9916-26. PMID 21098705 DOI: 10.1158/0008-5472.Can-10-0440 |
0.406 |
|
2010 |
Ljungman M. The DNA damage response--repair or despair? Environmental and Molecular Mutagenesis. 51: 879-89. PMID 20818630 DOI: 10.1002/Em.20597 |
0.413 |
|
2010 |
Karnak D, Dai Y, DeSano JT, Tang W, Ljungman M, Lawrence TS, Xu L. Abstract 1394: Pro-apoptotic and anti-tumorigenic effects of a naturally occurring proteasome inhibitor on hormone-refractory prostate cancer Cancer Research. 70: 1394-1394. DOI: 10.1158/1538-7445.Am10-1394 |
0.439 |
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2009 |
Dai Y, DeSano JT, Meng Y, Ji Q, Ljungman M, Lawrence TS, Xu L. Celastrol potentiates radiotherapy by impairment of DNA damage processing in human prostate cancer. International Journal of Radiation Oncology, Biology, Physics. 74: 1217-25. PMID 19545787 DOI: 10.1016/J.Ijrobp.2009.03.057 |
0.329 |
|
2009 |
Derheimer FA, Hicks JK, Paulsen MT, Canman CE, Ljungman M. Psoralen-lnduced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner Molecular Pharmacology. 75: 599-607. PMID 19064630 DOI: 10.1124/Mol.108.051698 |
0.791 |
|
2009 |
Lee C, Dosch J, Wang L, Ljungman M, Simeone D. PL4. Expression of ATDC in Pancreatic Cancer Stem Cells Confers Resistance to DNA Damage Journal of Surgical Research. 151: 227. DOI: 10.1016/J.Jss.2008.11.135 |
0.377 |
|
2008 |
Salmon AB, Ljungman M, Miller RA. Cells from long-lived mutant mice exhibit enhanced repair of ultraviolet lesions. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 219-31. PMID 18375871 DOI: 10.1093/Gerona/63.3.219 |
0.408 |
|
2008 |
Burkitt K, Ljungman M. Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin. Molecular Cancer. 7: 24. PMID 18325101 DOI: 10.1186/1476-4598-7-24 |
0.383 |
|
2008 |
Barnes D, Wang L, Ljungman M, Simeone D. 203. ATDC, A Novel DNA Damage Response Protein, Is Highly Expressed in Pancreatic Cancer Journal of Surgical Research. 144: 267-268. DOI: 10.1016/J.Jss.2007.12.231 |
0.404 |
|
2008 |
Lee CJ, Simeone DM, Lee C, Zielske S, Dosch J, Ljungman M. 140. Pancreatic Cancer Stem Cells are Resistant to Ionizing Radiation and the Chemotherapeutic Agent Gemcitabine Journal of Surgical Research. 144: 238. DOI: 10.1016/J.Jss.2007.12.159 |
0.301 |
|
2007 |
Lopez CA, Feng FY, Herman JM, Nyati MK, Lawrence TS, Ljungman M. Phenylbutyrate sensitizes human glioblastoma cells lacking wild-type p53 function to ionizing radiation. International Journal of Radiation Oncology, Biology, Physics. 69: 214-20. PMID 17707275 DOI: 10.1016/J.Ijrobp.2007.04.069 |
0.397 |
|
2007 |
Ljungman M. The transcription stress response. Cell Cycle (Georgetown, Tex.). 6: 2252-7. PMID 17700065 DOI: 10.4161/Cc.6.18.4751 |
0.485 |
|
2007 |
Derheimer FA, O'Hagan HM, Krueger HM, Hanasoge S, Paulsen MT, Ljungman M. RPA and ATR link transcriptional stress to p53. Proceedings of the National Academy of Sciences of the United States of America. 104: 12778-83. PMID 17616578 DOI: 10.1073/Pnas.0705317104 |
0.77 |
|
2007 |
Burkitt K, Ljungman M. Compromised Fanconi anemia response due to BRCA1 deficiency in cisplatin-sensitive head and neck cancer cell lines. Cancer Letters. 253: 131-7. PMID 17321670 DOI: 10.1016/J.Canlet.2007.01.017 |
0.391 |
|
2006 |
Nyati MK, Feng FY, Maheshwari D, Varambally S, Zielske SP, Ahsan A, Chun PY, Arora VA, Davis MA, Jung M, Ljungman M, Canman CE, Chinnaiyan AM, Lawrence TS. Ataxia telangiectasia mutated down-regulates phospho-extracellular signal-regulated kinase 1/2 via activation of MKP-1 in response to radiation. Cancer Research. 66: 11554-9. PMID 17178844 DOI: 10.1158/0008-5472.Can-06-1935 |
0.371 |
|
2006 |
Paulsen MT, Starks AM, Derheimer FA, Hanasoge S, Li L, Dixon JE, Ljungman M. The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. Molecular Cancer. 5: 25. PMID 16784539 DOI: 10.1186/1476-4598-5-25 |
0.771 |
|
2005 |
Paulsen MT, Ljungman M. The natural toxin juglone causes degradation of p53 and induces rapid H2AX phosphorylation and cell death in human fibroblasts. Toxicology and Applied Pharmacology. 209: 1-9. PMID 16271620 DOI: 10.1016/j.taap.2005.03.005 |
0.426 |
|
2005 |
Derheimer FA, Chang CW, Ljungman M. Transcription inhibition: a potential strategy for cancer therapeutics. European Journal of Cancer (Oxford, England : 1990). 41: 2569-76. PMID 16213135 DOI: 10.1016/J.Ejca.2005.08.012 |
0.783 |
|
2005 |
Ljungman M. Mechanisms of DNA repairIntroduction Mutation Research. 577: 1-3. PMID 16140049 DOI: 10.1016/J.Mrfmmm.2005.04.009 |
0.33 |
|
2005 |
Ljungman M. Activation of DNA damage signaling. Mutation Research. 577: 203-16. PMID 15922368 DOI: 10.1016/J.Mrfmmm.2005.02.014 |
0.379 |
|
2004 |
Ljungman M, Lane DP. Transcription - guarding the genome by sensing DNA damage. Nature Reviews. Cancer. 4: 727-37. PMID 15343279 DOI: 10.1038/Nrc1435 |
0.354 |
|
2004 |
O'Hagan HM, Ljungman M. Efficient NES-dependent protein nuclear export requires ongoing synthesis and export of mRNAs. Experimental Cell Research. 297: 548-59. PMID 15212955 DOI: 10.1016/J.Yexcr.2004.03.051 |
0.689 |
|
2004 |
Murphy PJ, Galigniana MD, Morishima Y, Harrell JM, Kwok RP, Ljungman M, Pratt WB. Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. The Journal of Biological Chemistry. 279: 30195-201. PMID 15145929 DOI: 10.1074/Jbc.M403539200 |
0.36 |
|
2004 |
O'Hagan HM, Ljungman M. Nuclear accumulation of p53 following inhibition of transcription is not due to diminished levels of MDM2. Oncogene. 23: 5505-12. PMID 15094782 DOI: 10.1038/Sj.Onc.1207709 |
0.745 |
|
2004 |
O'Hagan HM, Ljungman M. Phosphorylation and nuclear accumulation are distinct events contributing to the activation of p53. Mutation Research. 546: 7-15. PMID 14757188 DOI: 10.1016/J.Mrfmmm.2003.10.003 |
0.727 |
|
2004 |
Ljungman M, Nyati M, Herman J. Phenylbutyrate (a histone deacetylase inhibitor) and small inhibitory RNA silencing of p21 results in enhanced radiosensitization of human glioma cell lines International Journal of Radiation Oncology*Biology*Physics. 60: S350-S351. DOI: 10.1016/J.Ijrobp.2004.07.183 |
0.405 |
|
2003 |
Yanamadala S, Ljungman M. Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates. Molecular Cancer Research : McR. 1: 747-54. PMID 12939400 |
0.468 |
|
2002 |
McKay BC, Becerril C, Spronck JC, Ljungman M. Ultraviolet light-induced apoptosis is associated with S-phase in primary human fibroblasts. Dna Repair. 1: 811-20. PMID 12531028 DOI: 10.1016/S1568-7864(02)00109-X |
0.4 |
|
2002 |
Dyer ES, Paulsen MT, Markwart SM, Goh M, Livant DL, Ljungman M. Phenylbutyrate inhibits the invasive properties of prostate and breast cancer cell lines in the sea urchin embryo basement membrane invasion assay. International Journal of Cancer. Journal International Du Cancer. 101: 496-9. PMID 12216080 DOI: 10.1002/Ijc.10609 |
0.366 |
|
2002 |
Billecke CA, Ljungman ME, McKay BC, Rehemtulla A, Taneja N, Ethier SP. Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells. Oncogene. 21: 4481-9. PMID 12085226 DOI: 10.1038/Sj.Onc.1205546 |
0.3 |
|
2001 |
McKay BC, Becerril C, Ljungman M. P53 plays a protective role against UV- and cisplatin-induced apoptosis in transcription-coupled repair proficient fibroblasts. Oncogene. 20: 6805-8. PMID 11709715 DOI: 10.1038/Sj.Onc.1204901 |
0.435 |
|
2001 |
Ljungman M, O'Hagan HM, Paulsen MT. Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation. Oncogene. 20: 5964-71. PMID 11593403 DOI: 10.1038/Sj.Onc.1204734 |
0.772 |
|
2001 |
Goh M, Chen F, Paulsen MT, Yeager AM, Dyer ES, Ljungman M. Phenylbutyrate attenuates the expression of Bcl-X(L), DNA-PK, caveolin-1, and VEGF in prostate cancer cells. Neoplasia (New York, N.Y.). 3: 331-8. PMID 11571633 DOI: 10.1038/Sj.Neo.7900165 |
0.421 |
|
2001 |
Klibanov SA, O'Hagan HM, Ljungman M. Accumulation of soluble and nucleolar-associated p53 proteins following cellular stress. Journal of Cell Science. 114: 1867-73. PMID 11329373 |
0.72 |
|
2001 |
States JC, McGregor WG, Ljungman M. 2nd Annual Midwest DNA Repair Symposium, University of Louisville, Louisville, KY 20-21 May 2000. Mutation Research. 461: 163-7. PMID 11188758 DOI: 10.1016/S0921-8777(00)00045-8 |
0.317 |
|
2001 |
McKay BC, Chen F, Clarke ST, Wiggin HE, Harley LM, Ljungman M. UV light-induced degradation of RNA polymerase II is dependent on the Cockayne's syndrome A and B proteins but not p53 or MLH1. Mutation Research. 485: 93-105. PMID 11182541 DOI: 10.1016/S0921-8777(00)00064-1 |
0.454 |
|
2000 |
Ljungman M. Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress. Neoplasia (New York, N.Y.). 2: 208-25. PMID 10935507 DOI: 10.1038/SJ.NEO.7900073 |
0.387 |
|
2000 |
McKay BC, Ljungman M. Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light. Neoplasia (New York, N.Y.). 1: 276-84. PMID 10935482 DOI: 10.1038/Sj.Neo.7900028 |
0.503 |
|
2000 |
McKay BC, Chen F, Perumalswami CR, Zhang F, Ljungman M. The tumor suppressor p53 can both stimulate and inhibit ultraviolet light-induced apoptosis. Molecular Biology of the Cell. 11: 2543-51. PMID 10930452 DOI: 10.1091/Mbc.11.8.2543 |
0.504 |
|
2000 |
Li L, Ljungman M, Dixon JE. The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53 Journal of Biological Chemistry. 275: 2410-2414. PMID 10644693 DOI: 10.1074/Jbc.275.4.2410 |
0.348 |
|
1999 |
McKay BC, Ljungman M, Rainbow AJ. Potential roles for p53 in nucleotide excision repair. Carcinogenesis. 20: 1389-96. PMID 10426782 DOI: 10.1093/Carcin/20.8.1389 |
0.473 |
|
1999 |
Ljungman M. Recovery of RNA synthesis from the DHFR gene following UV-irradiation precedes the removal of photolesions from the transcribed strand. Carcinogenesis. 20: 395-9. PMID 10190552 DOI: 10.1093/Carcin/20.3.395 |
0.36 |
|
1999 |
Ljungman M, Zhang F, Chen F, Rainbow AJ, McKay BC. Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene. 18: 583-92. PMID 9989808 DOI: 10.1038/Sj.Onc.1202356 |
0.405 |
|
1999 |
Ljungman M. Repair of Radiation-Induced DNA Strand Breaks Does Not Occur Preferentially in Transcriptionally Active DNA Radiation Research. 152: 444. DOI: 10.2307/3580230 |
0.387 |
|
1998 |
McKay BC, Ljungman M, Rainbow AJ. Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis. Oncogene. 17: 545-55. PMID 9704920 DOI: 10.1038/Sj.Onc.1201963 |
0.541 |
|
1998 |
Chung DH, Zhang F, Chen F, McLaughlin WP, Ljungman M. Butyrate Attenuates BCLX L Expression in Human Fibroblasts and Acts in Synergy with Ionizing Radiation to Induce Apoptosis Radiation Research. 149: 187. DOI: 10.2307/3579929 |
0.343 |
|
1997 |
Chung DH, Ljungman M, Zhang F, Chen F, McLaughlin WP. 85 Butyrate down regulates BCL-XL and sensitizes human fibroblasts to radiation and chemotherapy induced apoptosis International Journal of Radiation Oncology*Biology*Physics. 39: 177. DOI: 10.1016/S0360-3016(97)80642-6 |
0.334 |
|
1996 |
Ljungman M. Effect of differential gene expression on the chromatin structure of the DHFR gene domain in vivo. Biochimica Et Biophysica Acta. 1307: 171-7. PMID 8679702 DOI: 10.1016/0167-4781(96)00037-1 |
0.396 |
|
1996 |
Ljungman M, Hanawalt PC. The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription. Carcinogenesis. 17: 31-5. PMID 8565133 DOI: 10.1093/Carcin/17.1.31 |
0.416 |
|
1995 |
Ljungman M, Hanawalt PC. Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivo. Nucleic Acids Research. 23: 1782-9. PMID 7784183 DOI: 10.1093/Nar/23.10.1782 |
0.439 |
|
1992 |
Ljungman M, Hanawalt PC. Correction: Localized Torsional Tension in the DNA of Human Cells Proceedings of the National Academy of Sciences of the United States of America. 89: 9364. DOI: 10.1073/Pnas.89.19.9364C |
0.349 |
|
1989 |
Ljungman M. Pretreatment with UV light renders the chromatin in human fibroblasts more susceptible to the DNA-damaging agents bleomycin, gamma radiation and 8-methoxypsoralen. Carcinogenesis. 10: 447-51. PMID 2466584 DOI: 10.1093/Carcin/10.3.447 |
0.402 |
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