Barry Sleckman - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Cell Biology, Molecular Biology

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chen BR, Sleckman BP. The regulation of DNA end resection by chromatin response to DNA double strand breaks. Frontiers in Cell and Developmental Biology. 10: 932633. PMID 35912102 DOI: 10.3389/fcell.2022.932633  0.446
2022 Chen BR, Tyler JK, Sleckman BP. A Flow Cytometry-Based Method for Analyzing DNA End Resection in G- and G-Phase Mammalian Cells. Bio-Protocol. 12: e4413. PMID 35813018 DOI: 10.21769/BioProtoc.4413  0.447
2022 Fowler FC, Chen BR, Zolnerowich N, Wu W, Pavani R, Paiano J, Peart C, Chen Z, Nussenzweig A, Sleckman BP, Tyler JK. DNA-PK promotes DNA end resection at DNA double strand breaks in G cells. Elife. 11. PMID 35575473 DOI: 10.7554/eLife.74700  0.414
2022 Chen BR, Sleckman BP. A Whole Genome CRISPR/Cas9 Screening Approach for Identifying Genes Encoding DNA End-Processing Proteins. Methods in Molecular Biology (Clifton, N.J.). 2444: 15-27. PMID 35290629 DOI: 10.1007/978-1-0716-2063-2_2  0.465
2021 Paiano J, Zolnerowich N, Wu W, Pavani R, Wang C, Li H, Zheng L, Shen B, Sleckman BP, Chen BR, Nussenzweig A. Role of 53BP1 in end protection and DNA synthesis at DNA breaks. Genes & Development. PMID 34503990 DOI: 10.1101/gad.348667.121  0.417
2021 Chen BR, Wang Y, Shen ZJ, Bennett A, Hindi I, Tyler JK, Sleckman BP. The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining. Dna Repair. 108: 103217. PMID 34481157 DOI: 10.1016/j.dnarep.2021.103217  0.428
2021 Chen BR, Wang Y, Tubbs A, Zong D, Fowler FC, Zolnerowich N, Wu W, Bennett A, Chen CC, Feng W, Nussenzweig A, Tyler JK, Sleckman BP. LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells. Elife. 10. PMID 34477552 DOI: 10.7554/eLife.68466  0.429
2020 Collins PL, Purman C, Porter SI, Nganga V, Saini A, Hayer KE, Gurewitz GL, Sleckman BP, Bednarski JJ, Bassing CH, Oltz EM. DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner. Nature Communications. 11: 3158. PMID 32572033 DOI: 10.1038/S41467-020-16926-X  0.433
2020 Chu SH, Chabon JR, Matovina CN, Minehart JC, Chen BR, Zhang J, Kumar V, Xiong Y, Callen E, Hung PJ, Feng Z, Koche RP, Liu XS, Chaudhuri J, Nussenzweig A, ... Sleckman BP, et al. Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development. Iscience. 23: 100941. PMID 32169821 DOI: 10.1016/J.Isci.2020.100941  0.426
2019 Innes CL, Hesse JE, Morales AJ, Helmink BA, Schurman SH, Sleckman BP, Paules RS. DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes. Cell Cycle (Georgetown, Tex.). 1-17. PMID 31757180 DOI: 10.1080/15384101.2019.1693118  0.726
2019 Purman CE, Collins PL, Porter SI, Saini A, Gupta H, Sleckman BP, Oltz EM. Regional gene repression by DNA double-strand breaks in G phase cells. Molecular and Cellular Biology. PMID 31591143 DOI: 10.1128/Mcb.00181-19  0.441
2019 Chen BR, Quinet A, Byrum AK, Jackson J, Berti M, Thangavel S, Bredemeyer AL, Hindi I, Mosammaparast N, Tyler JK, Vindigni A, Sleckman BP. XLF and H2AX function in series to promote replication fork stability. The Journal of Cell Biology. PMID 31123184 DOI: 10.1083/jcb.201808134  0.764
2019 Bednarski JJ, Sleckman BP. At the intersection of DNA damage and immune responses. Nature Reviews. Immunology. PMID 30778174 DOI: 10.1038/S41577-019-0135-6  0.416
2018 Hung PJ, Johnson B, Chen BR, Byrum AK, Bredemeyer AL, Yewdell WT, Johnson TE, Lee BJ, Deivasigamani S, Hindi I, Amatya P, Gross ML, Paull TT, Pisapia DJ, Chaudhuri J, ... ... Sleckman BP, et al. MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining. Molecular Cell. PMID 30017584 DOI: 10.1016/J.Molcel.2018.06.018  0.742
2018 Huang TH, Shen ZJ, Sleckman BP, Tyler JK. The Histone Chaperone ASF1 Regulates the Activation of ATM and DNA-PKcs in Response to DNA Double-strand Breaks. Cell Cycle (Georgetown, Tex.). PMID 29954236 DOI: 10.1080/15384101.2018.1486165  0.436
2018 Huang TH, Fowler F, Chen CC, Shen ZJ, Sleckman B, Tyler JK. The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells. Molecular Cell. PMID 29478807 DOI: 10.1016/J.Molcel.2018.01.031  0.507
2018 Chu SH, Chabon J, Minehart J, Matovina CN, Zhang J, Chen B, Callen-Moreu E, Hung PJ, Feng Z, Koche R, Liu XS, Chaudhuri J, Nussenzweig A, Sleckman B, Armstrong SA. The Lysine Histone Methyltransferase SETD2 Is Required for Appropriate Immunoglobulin VDJ Recombination Blood. 132: 511-511. DOI: 10.1182/Blood-2018-99-111952  0.486
2017 Bredemeyer AL, Edwards BS, Haynes MK, Morales AJ, Wang Y, Ursu O, Waller A, Sklar LA, Sleckman BP. High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining. Slas Discovery : Advancing Life Sciences R & D. 2472555217746324. PMID 29232168 DOI: 10.1177/2472555217746324  0.709
2017 Morales AJ, Carrero JA, Hung PJ, Tubbs AT, Andrews JM, Edelson BT, Calderon B, Innes CL, Paules RS, Payton JE, Sleckman BP. A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages. Elife. 6. PMID 28362262 DOI: 10.7554/Elife.24655  0.372
2016 Hung PJ, Chen BR, George R, Liberman C, Morales AJ, Colon-Ortiz P, Tyler JK, Sleckman BP, Bredemeyer AL. Deficiency of XLF and PAXX Prevents DNA Double-Strand Break Repair by Non-homologous End Joining in Lymphocytes. Cell Cycle (Georgetown, Tex.). 0. PMID 27830975 DOI: 10.1080/15384101.2016.1253640  0.776
2016 Canela A, Sridharan S, Sciascia N, Tubbs A, Meltzer P, Sleckman BP, Nussenzweig A. DNA Breaks and End Resection Measured Genome-wide by End Sequencing. Molecular Cell. PMID 27477910 DOI: 10.1016/J.Molcel.2016.06.034  0.398
2016 Brauer PM, Pessach IM, Clarke E, Rowe JH, Ott de Bruin L, Lee YN, Dominguez-Brauer C, Comeau AM, Awong G, Felgentreff K, Zhang YH, Bredemeyer A, Al-Herz W, Du L, Ververs F, ... ... Sleckman BP, et al. Modeling altered T-cell development with human induced pluripotent stem cells from patients with RAG1 mutations and distinct immunological phenotypes. Blood. PMID 27301863 DOI: 10.1182/Blood-2015-10-676304  0.652
2016 Bednarski JJ, Pandey R, Schulte E, White LS, Chen BR, Sandoval GJ, Kohyama M, Haldar M, Nickless A, Trott A, Cheng G, Murphy KM, Bassing CH, Payton JE, Sleckman BP. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals. The Journal of Experimental Medicine. PMID 26834154 DOI: 10.1084/Jem.20151048  0.434
2015 Felgentreff K, Lee YN, Frugoni F, Du L, van der Burg M, Giliani S, Tezcan I, Reisli I, Mejstrikova E, de Villartay JP, Sleckman BP, Manis J, Notarangelo LD. Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency. The Journal of Allergy and Clinical Immunology. 136: 140-150.e7. PMID 25917813 DOI: 10.1016/j.jaci.2015.03.005  0.355
2015 Bredemeyer AL, Sleckman BP. DNA damage responses: beyond double-strand break repair. Current Biology : Cb. 25: R45-6. PMID 25562302 DOI: 10.1016/j.cub.2014.11.024  0.785
2014 Dorsett Y, Zhou Y, Tubbs AT, Chen BR, Purman C, Lee BS, George R, Bredemeyer AL, Zhao JY, Sodergen E, Weinstock GM, Han ND, Reyes A, Oltz EM, Dorsett D, ... ... Sleckman BP, et al. HCoDES reveals chromosomal DNA end structures with single-nucleotide resolution. Molecular Cell. 56: 808-18. PMID 25435138 DOI: 10.1016/J.Molcel.2014.10.024  0.762
2014 Tubbs AT, Dorsett Y, Chan E, Helmink B, Lee BS, Hung P, George R, Bredemeyer AL, Mittal A, Pappu RV, Chowdhury D, Mosammaparast N, Krangel MS, Sleckman BP. KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes. Molecular and Cellular Biology. 34: 2811-21. PMID 24842905 DOI: 10.1128/Mcb.00441-14  0.838
2014 Makharashvili N, Tubbs AT, Yang SH, Wang H, Barton O, Zhou Y, Deshpande RA, Lee JH, Lobrich M, Sleckman BP, Wu X, Paull TT. Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection. Molecular Cell. 54: 1022-33. PMID 24837676 DOI: 10.1016/J.Molcel.2014.04.011  0.397
2014 Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, et al. β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6. PMID 24371308 DOI: 10.1073/Pnas.1315752111  0.74
2013 Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, ... Sleckman BP, et al. Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination. Molecular and Cellular Biology. 33: 3568-79. PMID 23836881 DOI: 10.1128/Mcb.00308-13  0.834
2013 Callen E, Di Virgilio M, Kruhlak MJ, Nieto-Soler M, Wong N, Chen HT, Faryabi RB, Polato F, Santos M, Starnes LM, Wesemann DR, Lee JE, Tubbs A, Sleckman BP, Daniel JA, et al. 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions. Cell. 153: 1266-80. PMID 23727112 DOI: 10.1016/J.Cell.2013.05.023  0.421
2013 Innes CL, Hesse JE, Palii SS, Helmink BA, Holub AJ, Sleckman BP, Paules RS. DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs. Bmc Genomics. 14: 163. PMID 23496831 DOI: 10.1186/1471-2164-14-163  0.763
2013 Steinel NC, Lee BS, Tubbs AT, Bednarski JJ, Schulte E, Yang-Iott KS, Schatz DG, Sleckman BP, Bassing CH. The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements. The Journal of Experimental Medicine. 210: 233-9. PMID 23382544 DOI: 10.1084/Jem.20121605  0.418
2012 Bednarski JJ, Sleckman BP. Lymphocyte development: integration of DNA damage response signaling. Advances in Immunology. 116: 175-204. PMID 23063077 DOI: 10.1016/B978-0-12-394300-2.00006-5  0.529
2012 Bednarski JJ, Sleckman BP. Integrated signaling in developing lymphocytes: the role of DNA damage responses. Cell Cycle (Georgetown, Tex.). 11: 4129-34. PMID 23032308 DOI: 10.4161/Cc.22021  0.456
2012 Yin B, Lee BS, Yang-Iott KS, Sleckman BP, Bassing CH. Redundant and nonredundant functions of ATM and H2AX in αβ T-lineage lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 189: 1372-9. PMID 22730535 DOI: 10.4049/Jimmunol.1200829  0.35
2012 Helmink BA, Sleckman BP. The response to and repair of RAG-mediated DNA double-strand breaks. Annual Review of Immunology. 30: 175-202. PMID 22224778 DOI: 10.1146/Annurev-Immunol-030409-101320  0.794
2012 Bednarski JJ, Nickless A, Bhattacharya D, Amin RH, Schlissel MS, Sleckman BP. RAG-induced DNA double-strand breaks signal through Pim2 to promote pre-B cell survival and limit proliferation. The Journal of Experimental Medicine. 209: 11-7. PMID 22201128 DOI: 10.1084/Jem.20112078  0.351
2012 Trott A, Bednarski J, Sleckman B. Physiologic DNA Breaks Activate Non-canonical NFkB Signaling in Developing B Cells Journal of Allergy and Clinical Immunology. 129: AB12. DOI: 10.1016/J.Jaci.2011.12.908  0.368
2011 Kondilis-Mangum HD, Shih HY, Mahowald G, Sleckman BP, Krangel MS. Regulation of TCRβ allelic exclusion by gene segment proximity and accessibility. Journal of Immunology (Baltimore, Md. : 1950). 187: 6374-81. PMID 22079986 DOI: 10.4049/Jimmunol.1102611  0.697
2011 Mahowald GK, Mahowald MA, Moon C, Khor B, Sleckman BP. Out-of-frame T cell receptor beta transcripts are eliminated by multiple pathways in vivo. Plos One. 6: e21627. PMID 21765899 DOI: 10.1371/Journal.Pone.0021627  0.806
2011 Gapud EJ, Lee BS, Mahowald GK, Bassing CH, Sleckman BP. Repair of chromosomal RAG-mediated DNA breaks by mutant RAG proteins lacking phosphatidylinositol 3-like kinase consensus phosphorylation sites. Journal of Immunology (Baltimore, Md. : 1950). 187: 1826-34. PMID 21742970 DOI: 10.4049/Jimmunol.1101388  0.845
2011 Gapud EJ, Sleckman BP. Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination. Cell Cycle (Georgetown, Tex.). 10: 1928-35. PMID 21673501 DOI: 10.4161/Cc.10.12.16011  0.826
2011 Zhang S, Yajima H, Huynh H, Zheng J, Callen E, Chen HT, Wong N, Bunting S, Lin YF, Li M, Lee KJ, Story M, Gapud E, Sleckman BP, Nussenzweig A, et al. Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair. The Journal of Cell Biology. 193: 295-305. PMID 21482716 DOI: 10.1083/Jcb.201009074  0.791
2011 Gapud EJ, Dorsett Y, Yin B, Callen E, Bredemeyer A, Mahowald GK, Omi KQ, Walker LM, Bednarski JJ, McKinnon PJ, Bassing CH, Nussenzweig A, Sleckman BP. Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 2022-7. PMID 21245316 DOI: 10.1073/Pnas.1013295108  0.831
2011 Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, Walker LM, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes. Nature. 469: 245-9. PMID 21160476 DOI: 10.1038/Nature09585  0.781
2011 Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, M.walker L, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes (Nature 469 (2010) (245-249)) Nature. 472: 247. DOI: 10.1038/Nature09942  0.717
2010 Reavie L, Della Gatta G, Crusio K, Aranda-Orgilles B, Buckley SM, Thompson B, Lee E, Gao J, Bredemeyer AL, Helmink BA, Zavadil J, Sleckman BP, Palomero T, Ferrando A, Aifantis I. Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex. Nature Immunology. 11: 207-15. PMID 20081848 DOI: 10.1038/Ni.1839  0.765
2009 Yin B, Savic V, Juntilla MM, Bredemeyer AL, Yang-Iott KS, Helmink BA, Koretzky GA, Sleckman BP, Bassing CH. Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination. The Journal of Experimental Medicine. 206: 2625-39. PMID 19887394 DOI: 10.1084/Jem.20091320  0.842
2009 Mahowald GK, Baron JM, Mahowald MA, Kulkarni S, Bredemeyer AL, Bassing CH, Sleckman BP. Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis. Proceedings of the National Academy of Sciences of the United States of America. 106: 18339-44. PMID 19820166 DOI: 10.1073/Pnas.0902545106  0.813
2009 Gonzalez-Suarez I, Redwood AB, Perkins SM, Vermolen B, Lichtensztejin D, Grotsky DA, Morgado-Palacin L, Gapud EJ, Sleckman BP, Sullivan T, Sage J, Stewart CL, Mai S, Gonzalo S. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. The Embo Journal. 28: 2414-27. PMID 19629036 DOI: 10.1038/Emboj.2009.196  0.757
2009 Callén E, Bunting S, Huang CY, Difilippantonio MJ, Wong N, Khor B, Mahowald G, Kruhlak MJ, Ried T, Sleckman BP, Nussenzweig A. Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG. Cell Cycle (Georgetown, Tex.). 8: 2408-12. PMID 19556863 DOI: 10.4161/Cc.8.15.9085  0.829
2009 Savic V, Yin B, Maas NL, Bredemeyer AL, Carpenter AC, Helmink BA, Yang-Iott KS, Sleckman BP, Bassing CH. Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Molecular Cell. 34: 298-310. PMID 19450528 DOI: 10.1016/J.Molcel.2009.04.012  0.815
2009 Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nature Immunology. 10: 655-64. PMID 19448632 DOI: 10.1038/Ni.1735  0.383
2009 Dose M, Sleckman BP, Han J, Bredemeyer AL, Bendelac A, Gounari F. Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc. Proceedings of the National Academy of Sciences of the United States of America. 106: 8641-6. PMID 19423665 DOI: 10.1073/Pnas.0812255106  0.657
2009 Helmink BA, Bredemeyer AL, Lee BS, Huang CY, Sharma GG, Walker LM, Bednarski JJ, Lee WL, Pandita TK, Bassing CH, Sleckman BP. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. The Journal of Experimental Medicine. 206: 669-79. PMID 19221393 DOI: 10.1084/Jem.20081326  0.851
2009 Khor B, Mahowald GK, Khor K, Sleckman BP. Functional overlap in the cis-acting regulation of the V(D)J recombination at the TCRbeta locus. Molecular Immunology. 46: 321-6. PMID 19070901 DOI: 10.1016/J.Molimm.2008.10.030  0.818
2008 Mahowald GK, Baron JM, Sleckman BP. Collateral damage from antigen receptor gene diversification. Cell. 135: 1009-12. PMID 19070571 DOI: 10.1016/J.Cell.2008.11.024  0.759
2008 Difilippantonio S, Gapud E, Wong N, Huang CY, Mahowald G, Chen HT, Kruhlak MJ, Callen E, Livak F, Nussenzweig MC, Sleckman BP, Nussenzweig A. 53BP1 facilitates long-range DNA end-joining during V(D)J recombination. Nature. 456: 529-33. PMID 18931658 DOI: 10.1038/Nature07476  0.841
2008 Bredemeyer AL, Helmink BA, Innes CL, Calderon B, McGinnis LM, Mahowald GK, Gapud EJ, Walker LM, Collins JB, Weaver BK, Mandik-Nayak L, Schreiber RD, Allen PM, May MJ, Paules RS, ... ... Sleckman BP, et al. DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes. Nature. 456: 819-23. PMID 18849970 DOI: 10.1038/Nature07392  0.82
2008 Bredemeyer AL, Huang CY, Walker LM, Bassing CH, Sleckman BP. Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining. Journal of Immunology (Baltimore, Md. : 1950). 181: 2620-5. PMID 18684952 DOI: 10.4049/Jimmunol.181.4.2620  0.757
2008 Huang CY, Bredemeyer AL, Walker LM, Bassing CH, Sleckman BP. Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. European Journal of Immunology. 38: 342-9. PMID 18196519 DOI: 10.1002/Eji.200737972  0.651
2007 Tarakanova VL, Leung-Pineda V, Hwang S, Yang CW, Matatall K, Basson M, Sun R, Piwnica-Worms H, Sleckman BP, Virgin HW. Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host & Microbe. 1: 275-86. PMID 18005708 DOI: 10.1016/J.Chom.2007.05.008  0.336
2007 Bredemeyer AL, Sleckman BP. SWI-SNF: promoter of accessibility. Nature Immunology. 8: 795-6. PMID 17641658 DOI: 10.1038/ni0807-795  0.618
2007 Callén E, Jankovic M, Difilippantonio S, Daniel JA, Chen HT, Celeste A, Pellegrini M, McBride K, Wangsa D, Bredemeyer AL, Sleckman BP, Ried T, Nussenzweig M, Nussenzweig A. ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes Cell. 130: 63-75. PMID 17599403 DOI: 10.1016/J.Cell.2007.06.016  0.759
2006 Bredemeyer AL, Sharma GG, Huang CY, Helmink BA, Walker LM, Khor KC, Nuskey B, Sullivan KE, Pandita TK, Bassing CH, Sleckman BP. ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature. 442: 466-70. PMID 16799570 DOI: 10.1038/Nature04866  0.852
2006 Khor B, Bredemeyer AL, Huang CY, Turnbull IR, Evans R, Maggi LB, White JM, Walker LM, Carnes K, Hess RA, Sleckman BP. Proteasome activator PA200 is required for normal spermatogenesis Molecular and Cellular Biology. 26: 2999-3007. PMID 16581775 DOI: 10.1128/Mcb.26.8.2999-3007.2006  0.826
2005 Sleckman BP. Lymphocyte antigen receptor gene assembly: multiple layers of regulation. Immunologic Research. 32: 253-8. PMID 16106077 DOI: 10.1385/IR:32:1-3:253  0.341
2005 Khor B, Sleckman BP. Intra- and inter-allelic ordering of T cell receptor beta chain gene assembly. European Journal of Immunology. 35: 964-70. PMID 15719363 DOI: 10.1002/Eji.200425806  0.705
2005 Khor B, Wehrly TD, Sleckman BP. Chromosomal excision of TCRdelta chain genes is dispensable for alphabeta T cell lineage commitment. International Immunology. 17: 225-32. PMID 15642954 DOI: 10.1093/Intimm/Dxh202  0.724
2005 Jackson A, Kondilis HD, Khor B, Sleckman BP, Krangel MS. Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility. Nature Immunology. 6: 189-97. PMID 15640803 DOI: 10.1038/Ni1157  0.675
2004 Tillman RE, Wooley AL, Hughes MM, Khor B, Sleckman BP. Regulation of T-cell receptor beta-chain gene assembly by recombination signals: the beyond 12/23 restriction. Immunological Reviews. 200: 36-43. PMID 15242394 DOI: 10.1111/J.0105-2896.2004.00156.X  0.818
2003 Hughes MM, Tillman RE, Wehrly TD, White JM, Sleckman BP. The B12/23 restriction is critically dependent on recombination signal nonamer and spacer sequences. Journal of Immunology (Baltimore, Md. : 1950). 171: 6604-10. PMID 14662863 DOI: 10.4049/Jimmunol.171.12.6604  0.806
2003 Brewer JA, Khor B, Vogt SK, Muglia LM, Fujiwara H, Haegele KE, Sleckman BP, Muglia LJ. T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation. Nature Medicine. 9: 1318-22. PMID 12949501 DOI: 10.1038/Nm895  0.689
2003 Bassing CH, Tillman RE, Woodman BB, Canty D, Monroe RJ, Sleckman BP, Alt FW. T cell receptor (TCR) alpha/delta locus enhancer identity and position are critical for the assembly of TCR delta and alpha variable region genes. Proceedings of the National Academy of Sciences of the United States of America. 100: 2598-603. PMID 12604775 DOI: 10.1073/Pnas.0437943100  0.761
2003 Tillman RE, Wooley AL, Khor B, Wehrly TD, Little CA, Sleckman BP. Cutting edge: targeting of V beta to D beta rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors. Journal of Immunology (Baltimore, Md. : 1950). 170: 5-9. PMID 12496374 DOI: 10.4049/Jimmunol.170.1.5  0.794
2002 Khor B, Sleckman BP. Allelic exclusion at the TCRbeta locus. Current Opinion in Immunology. 14: 230-4. PMID 11869897 DOI: 10.1016/S0952-7915(02)00326-6  0.707
2002 Tillman RE, Wooley AL, Hughes MM, Wehrly TD, Swat W, Sleckman BP. Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination. The Journal of Experimental Medicine. 195: 309-16. PMID 11828005 DOI: 10.1084/Jem.20011803  0.851
2000 Bassing CH, Alt FW, Hughes MM, D'Auteuil M, Wehrly TD, Woodman BB, Gärtner F, White JM, Davidson L, Sleckman BP. Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule. Nature. 405: 583-6. PMID 10850719 DOI: 10.1038/35014635  0.427
1999 Monroe RJ, Sleckman BP, Monroe BC, Khor B, Claypool S, Ferrini R, Davidson L, Alt FW. Developmental regulation of TCR delta locus accessibility and expression by the TCR delta enhancer. Immunity. 10: 503-13. PMID 10367896 DOI: 10.1016/S1074-7613(00)80050-3  0.692
1998 Sleckman BP, Bassing CH, Bardon CG, Okada A, Khor B, Bories JC, Monroe R, Alt FW. Accessibility control of variable region gene assembly during T-cell development. Immunological Reviews. 165: 121-30. PMID 9850857 DOI: 10.1111/J.1600-065X.1998.Tb01235.X  0.717
1998 Sleckman BP, Khor B, Monroe R, Alt FW. Assembly of productive T cell receptor delta variable region genes exhibits allelic inclusion. The Journal of Experimental Medicine. 188: 1465-71. PMID 9782123 DOI: 10.1084/Jem.188.8.1465  0.716
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