Amanda M. Holland, Ph.D. - Publications

Affiliations: 
2013 Weill Cornell Medical College, New York, NY, United States 
Area:
Immunology, Cell Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Brentjens RJ, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, et al. Author Correction: Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors. Nature Biotechnology. PMID 38531977 DOI: 10.1038/s41587-024-02205-3  0.704
2018 Tsai JJ, Velardi E, Shono Y, Argyropoulos KV, Holland AM, Smith OM, Yim NL, Rao UK, Kreines FM, Lieberman SR, Young LF, Lazrak A, Youssef S, Fu YY, Liu C, et al. Nrf2 regulates CD4 T cell-induced acute graft-versus-host disease in mice. Blood. PMID 30381375 DOI: 10.1182/Blood-2017-10-812941  0.655
2017 White AJ, Baik S, Parnell SM, Holland AM, Brombacher F, Jenkinson WE, Anderson G. A type 2 cytokine axis for thymus emigration. The Journal of Experimental Medicine. PMID 28694386 DOI: 10.1084/Jem.20170271  0.449
2014 Velardi E, Tsai JJ, Holland AM, Wertheimer T, Yu VW, Zakrzewski JL, Tuckett AZ, Singer NV, West ML, Smith OM, Young LF, Kreines FM, Levy ER, Boyd RL, Scadden DT, et al. Sex steroid blockade enhances thymopoiesis by modulating Notch signaling. The Journal of Experimental Medicine. 211: 2341-9. PMID 25332287 DOI: 10.1182/Blood.V122.21.291.291  0.396
2014 Ghosh A, Holland AM, van den Brink MR. Genetically engineered donor T cells to optimize graft-versus-tumor effects across MHC barriers. Immunological Reviews. 257: 226-36. PMID 24329800 DOI: 10.1111/Imr.12142  0.636
2014 Anderson G, Baik S, Cowan JE, Holland AM, McCarthy NI, Nakamura K, Parnell SM, White AJ, Lane PJ, Jenkinson EJ, Jenkinson WE. Mechanisms of thymus medulla development and function. Current Topics in Microbiology and Immunology. 373: 19-47. PMID 23612988 DOI: 10.1007/82_2013_320  0.474
2013 Ghosh A, Holland AM, Dogan Y, Yim NL, Rao UK, Young LF, West ML, Singer NV, Lee H, Na IK, Tsai JJ, Jenq RR, Penack O, Hanash AM, Lezcano C, et al. PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD. Cancer Research. 73: 4687-96. PMID 23733752 DOI: 10.1158/0008-5472.Can-12-4699  0.663
2013 Ghosh A, Dogan Y, Moroz M, Holland AM, Yim NL, Rao UK, Young LF, Tannenbaum D, Masih D, Velardi E, Tsai JJ, Jenq RR, Penack O, Hanash AM, Smith OM, et al. Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity. The Journal of Clinical Investigation. 123: 2654-62. PMID 23676461 DOI: 10.1172/Jci66301  0.633
2013 Tsai JJ, Dudakov JA, Takahashi K, Shieh JH, Velardi E, Holland AM, Singer NV, West ML, Smith OM, Young LF, Shono Y, Ghosh A, Hanash AM, Tran HT, Moore MA, et al. Nrf2 regulates haematopoietic stem cell function. Nature Cell Biology. 15: 309-16. PMID 23434824 DOI: 10.1038/Ncb2699  0.342
2012 Holland AM, Zakrzewski JL, Tsai JJ, Hanash AM, Dudakov JA, Smith OM, West ML, Singer NV, Brill J, Sun JC, van den Brink MR. Extrathymic development of murine T cells after bone marrow transplantation. The Journal of Clinical Investigation. 122: 4716-26. PMID 23160195 DOI: 10.1172/Jci60630  0.61
2012 Hanash AM, Dudakov JA, Hua G, O'Connor MH, Young LF, Singer NV, West ML, Jenq RR, Holland AM, Kappel LW, Ghosh A, Tsai JJ, Rao UK, Yim NL, Smith OM, et al. Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease. Immunity. 37: 339-50. PMID 22921121 DOI: 10.1016/J.Immuni.2012.05.028  0.782
2012 Dudakov JA, Hanash AM, Jenq RR, Young LF, Ghosh A, Singer NV, West ML, Smith OM, Holland AM, Tsai JJ, Boyd RL, van den Brink MR. Interleukin-22 drives endogenous thymic regeneration in mice. Science (New York, N.Y.). 336: 91-5. PMID 22383805 DOI: 10.1126/Science.1218004  0.407
2012 Ghosh A, Davila ML, Young LF, Kloss C, Gunset G, Smith OM, West ML, Singer NV, Holland AM, Jenq RR, Hanash AM, Dudakov JA, Velardi E, Shono Y, Sadelain M, et al. CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd Blood. 120: 451-451. DOI: 10.1182/Blood.V120.21.451.451  0.549
2012 Hanash A, Dudakov J, Hua G, O'Connor M, Jenq R, Holland A, Smith O, Liu C, Fouser L, Kolesnick R, Blazar B, van den Brink M. Host-Derived IL-22 Protects Intestinal Stem Cells from GVHD Biology of Blood and Marrow Transplantation. 18: S361-S362. DOI: 10.1016/J.Bbmt.2011.12.419  0.421
2012 Ghosh A, Dogan Y, Holland AM, Young LF, West ML, Singer NV, Smith OM, Jenq RR, Na I-, Penack O, Hanash AM, Sauer MG, Sadelain M, Brink MRMvd. Trail Over-Expression on Donor T Cells Enhances GVT and Suppresses GVHD by Inhibiting Alloreactive T Cells and Impairing Host APC Functions Biology of Blood and Marrow Transplantation. 18. DOI: 10.1016/J.Bbmt.2011.12.416  0.589
2011 Lu SX, Kappel LW, Charbonneau-Allard AM, Atallah R, Holland AM, Turbide C, Hubbard VM, Rotolo JA, Smith M, Suh D, King C, Rao UK, Yim N, Bautista JL, Jenq RR, et al. Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation. Plos One. 6: e21611. PMID 21760897 DOI: 10.1371/Journal.Pone.0021611  0.781
2011 Hanash AM, Kappel LW, Yim NL, Nejat RA, Goldberg GL, Smith OM, Rao UK, Dykstra L, Na IK, Holland AM, Dudakov JA, Liu C, Murphy GF, Leonard WJ, Heller G, et al. Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL. Blood. 118: 446-55. PMID 21596854 DOI: 10.1182/blood-2010-07-294785  0.806
2011 Ghosh A, Dogan Y, Holland AM, Smith OM, Young LF, West ML, Singer NV, Jenq RR, Na I, Penack O, Hanash AM, Sauer MG, Sadelain M, van den Brink MR. Over-Expression of TRAIL on Donor T Cells Enhances GVT and Suppresses Gvhd Via Elimination of Alloreactive T Cells and Host APC Blood. 118: 817-817. DOI: 10.1182/Blood.V118.21.817.817  0.647
2011 Hanash AM, Dudakov JA, Hua G, Young LF, O'connor M, Jenq RR, Holland AM, Smith OM, Liu C, Fouser L, Kolesnick R, Blazar BR, Van Den Brink M. Host-Derived IL-22 Limits Graft Versus Host Disease and Protects the Intestinal Stem Cell Niche Blood. 118: 309-309. DOI: 10.1182/Blood.V118.21.309.309  0.515
2011 Dudakov JA, Hanash AM, Young LF, Singer NV, West ML, Jenq RR, Smith OM, Holland AM, Boyd RL, Brink MRMvd. Innate Lymphoid Cell-Derived IL-22 Mediates Endogenous Thymic Repair Under the Control of IL-23 Blood. 118: 143-143. DOI: 10.1182/Blood.V118.21.143.143  0.393
2011 Ghosh A, Holland AM, Dogan Y, Yim N, Rao UK, Young LF, Smith OM, Jenq R, Na I, Tsai JJ, Singer N, West M, Penack O, Hanash AM, Sant'Angelo D, et al. Abstract 4743: Genetically engineered allogeneic T Cells for BMT immunotherapy: Expression of TRAIL and PLZF selectively enhances GVT and abrogates GVHD Cancer Research. 71: 4743-4743. DOI: 10.1158/1538-7445.Am2011-4743  0.642
2011 Tsai JJ, Tran H, Smith OM, Yim N, Rao U, Takahashi K, Ghosh A, Na I-, Jenq R, Hanash A, Holland A, Brink MRMvd. Nrf2 Regulates Alloreactive T Cell Function During GVHD Biology of Blood and Marrow Transplantation. 17. DOI: 10.1016/J.Bbmt.2010.12.530  0.531
2011 Ghosh A, Holland AM, Dogan Y, Yim N, Rao UK, Young LF, Smith OM, Jenq R, Na I-, Tsai JJ, Singer N, West M, Penack O, Hanash AM, Sauer MG, et al. Genetically Engineered Donor T Cells for BMT Immunotherapy: Expression of Trail and PLZF Selectively Enhances GVT and Abrogates GVHD Biology of Blood and Marrow Transplantation. 17. DOI: 10.1016/J.Bbmt.2010.12.521  0.504
2011 Holland AM, Zakrzewski JL, Fletcher AL, Smith OM, Suh D, King CG, Yim NL, Rao UK, Brill J, Brink MRvd. Extrathymic Sites Drive Thymus-Independent Development of Functional T Cells After Bone Marrow Transplantation Biology of Blood and Marrow Transplantation. 17. DOI: 10.1016/J.Bbmt.2010.12.249  0.54
2010 Lu SX, Holland AM, Na IK, Terwey TH, Alpdogan O, Bautista JL, Smith OM, Suh D, King C, Kochman A, Hubbard VM, Rao UK, Yim N, Liu C, Laga AC, et al. Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease. Journal of Immunology (Baltimore, Md. : 1950). 185: 1912-9. PMID 20622117 DOI: 10.4049/Jimmunol.0903148  0.761
2010 Na IK, Markley JC, Tsai JJ, Yim NL, Beattie BJ, Klose AD, Holland AM, Ghosh A, Rao UK, Stephan MT, Serganova I, Santos EB, Brentjens RJ, Blasberg RG, Sadelain M, et al. Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo. Blood. 116: e18-25. PMID 20511541 DOI: 10.1182/Blood-2009-12-259432  0.592
2010 Penack O, Henke E, Suh D, King CG, Smith OM, Na IK, Holland AM, Ghosh A, Lu SX, Jenq RR, Liu C, Murphy GF, Lu TT, May C, Scheinberg DA, et al. Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth. Journal of the National Cancer Institute. 102: 894-908. PMID 20463307 DOI: 10.1093/Jnci/Djq172  0.711
2010 Na IK, Lu SX, Yim NL, Goldberg GL, Tsai J, Rao U, Smith OM, King CG, Suh D, Hirschhorn-Cymerman D, Palomba L, Penack O, Holland AM, Jenq RR, Ghosh A, et al. The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. The Journal of Clinical Investigation. 120: 343-56. PMID 19955659 DOI: 10.1172/Jci39395  0.78
2010 Ghosh A, Holland AM, Dogan Y, Yim N, Rao UK, Young LF, Smith OM, Jenq R, Na I, Tsai J, Penack O, Hanash AM, Sauer MG, Sant'Angelo D, Sadelain M, et al. Genetic Engineering of Donor T Cells for BMT Immunotherapy: Expression of TRAIL and PLZF Selectively Enhances GVT and Abrogates Gvhd Blood. 116: 730-730. DOI: 10.1182/Blood.V116.21.730.730  0.639
2010 Dudakov JA, Hanash AM, Rao UK, Holland AM, Jenq R, Goldberg GL, Boyd R, Brink MRMvd. Gvhd, Hematopoietic Dysfunction, and Post-Transplant Immune Deficiency: Loss of Marrow Function Leads to Ineffective Extramedullary Hematopoiesis, However Lymphoid Reconstitution Is Restored by the Synergistic Effects of KGF, Sex Steroid Ablation, and Precursor T Cell Adoptive Therapy. Blood. 116: 1468-1468. DOI: 10.1182/Blood.V116.21.1468.1468  0.572
2010 Lu SX, Palomba ML, Na I-, Terwey TH, Alpdogan O, Bautista JL, Smith M, Suh D, King CG, Rao UK, Yim N, Jenq RR, Zakrzewski JL, Holland AM, Penack O, et al. P-Selectin Regulates Leukocyte Trafficking And Experimental Graft-Versus-Host-Disease After Allogeneic Bone Marrow Transplantation Biology of Blood and Marrow Transplantation. 16. DOI: 10.1016/J.Bbmt.2009.12.453  0.7
2010 Lu SX, Na I-, Yim N, Goldberg GL, Tsai J, Rao UK, Smith M, King CG, Suh D, Hirschorn-Cymerman D, Palomba ML, Penack O, Holland AM, Jenq RR, Ghosh A, et al. TRAIL/DR5 Interactions Are Important For Mediating Thymic Damage After Allogeneic Bone Marrow Transplantation Biology of Blood and Marrow Transplantation. 16. DOI: 10.1016/J.Bbmt.2009.12.452  0.674
2010 Ghosh A, Holland AM, Kappel LW, Dogan Y, Yim N, Rao U, Smith OM, Jenq RR, Zakrzewski J, Na I-, Lu S, Tsai J, Penack O, Hanash A, Sauer MG, et al. Over-Expression Of Trail On Donor T Cells Simultaneously Ameliorates GVHD And Enhances GVT Biology of Blood and Marrow Transplantation. 16. DOI: 10.1016/J.Bbmt.2009.12.434  0.789
2009 Penack O, Smith OM, Cunningham-Bussel A, Liu X, Rao U, Yim N, Na IK, Holland AM, Ghosh A, Lu SX, Jenq RR, Liu C, Murphy GF, Brandl K, van den Brink MR. NOD2 regulates hematopoietic cell function during graft-versus-host disease. The Journal of Experimental Medicine. 206: 2101-10. PMID 19737867 DOI: 10.1084/jem.20090623  0.765
2009 Holland AM, van den Brink MR. Rejuvenation of the aging T cell compartment. Current Opinion in Immunology. 21: 454-9. PMID 19608394 DOI: 10.1016/J.Coi.2009.06.002  0.528
2009 Jenq RR, King CG, Volk C, Suh D, Smith OM, Rao UK, Yim NL, Holland AM, Lu SX, Zakrzewski JL, Goldberg GL, Diab A, Alpdogan O, Penack O, Na IK, et al. Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation. Blood. 113: 1574-80. PMID 19011222 DOI: 10.1182/Blood-2008-05-155697  0.782
2009 Kappel LW, Goldberg GL, King CG, Suh DY, Smith OM, Ligh C, Holland AM, Grubin J, Mark NM, Liu C, Iwakura Y, Heller G, van den Brink MR. IL-17 contributes to CD4-mediated graft-versus-host disease. Blood. 113: 945-52. PMID 18931341 DOI: 10.1182/Blood-2008-08-172155  0.799
2009 Na I, Markley J, Tsai J, Yim NL, Beattie BJ, Klose AD, Holland AM, Ghosh A, Rao UK, Stephan M, Serganova I, Brentjens RJ, Blasberg RR, Sadelain MW, van den Brink MR. Concurrent Visualization of Trafficking and NFAT Signalling in Primary T Lymphocytes and T Cell Precursors In Vivo. Blood. 114: 914-914. DOI: 10.1182/Blood.V114.22.914.914  0.563
2009 Na I, Lu SX, Yim NL, Goldberg GL, Tsai J, Rao UK, Smith OM, King C, Suh D, Hirschhorn-Cymerman D, Palomba ML, Penack O, Holland AM, Jenq RR, Ghosh A, et al. TRAIL/ DR5 Interactions Are Important for Thymic Damage After Allogeneic Bone Marrow Transplantation. Blood. 114: 234-234. DOI: 10.1182/Blood.V114.22.234.234  0.782
2009 Lu SX, Palomba ML, Na I, Terwey T, Alpdogan O, Bautista JL, Smith MO, Suh D, King C, Rao U, Yim N, Jenq RR, Zakrzewski JL, Holland AM, Penack O, et al. P-Selectin in Recipients of Allogeneic Bone Marrow Transplantation Regulates Experimental Graft-Versus-Host-Disease. Blood. 114: 1335-1335. DOI: 10.1182/Blood.V114.22.1335.1335  0.763
2009 Lu SX, Na I-, Goldberg GL, Ghosh A, Hirschhorn-Cymerman D, King CG, Smith OM, Suh D, Rao U, Yim N, Holland AM, Penack O, Jenq RR, Teisch L, Meykler S, et al. The T Cell Cytolytic Molecules Fas Ligand And Trail, The Trafficking Molecules CCR9, β7 Integrin And PSGL1, And The Immune Modulating Molecules OX40 And Ceacam1 Are Required For Thymic Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 15: 123. DOI: 10.1016/J.Bbmt.2008.12.379  0.683
2009 Lu S, Willis L, Charbonneau-Allard A, Atallah R, Holland A, Turbide C, Hubbard V, Rotolo J, Smith O, Suh D, King C, Rao U, Yim N, Kochman A, Bautista J, et al. Ceacam1 Regulates Experimental Graft-Versus-Host-Disease Biology of Blood and Marrow Transplantation. 15: 13. DOI: 10.1016/J.Bbmt.2008.12.038  0.651
2009 Penack O, Henke E, Suh D, King C, Smith M, Na I, Holland A, Ghosh A, Lu S, Jenq R, Liu C, May C, Murphy G, Lu T, Gao D, et al. Depletion of Vascular Endothelial Progenitor Cells Simultaneously Ameliorates GVHD and Inhibits Tumor Growth Biology of Blood and Marrow Transplantation. 15: 1. DOI: 10.1016/J.Bbmt.2008.12.007  0.64
2008 Holland AM, Zakrzewski JL, Goldberg GL, Ghosh A, van den Brink MR. Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man. Seminars in Immunopathology. 30: 479-87. PMID 19015856 DOI: 10.1007/S00281-008-0138-Z  0.567
2008 Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Brentjens RJ, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, et al. Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors. Nature Biotechnology. 26: 453-61. PMID 18376399 DOI: 10.1038/Nbt1395  0.762
2008 Penack O, Henke E, Suh D, King C, Smith MO, Na I, Holland A, Ghosh A, Lu SX, Jenq R, Liu C, Murphy GF, Lu T, May C, Scheinberg DA, et al. Depletion of Vascular Endothelial Progenitor Cells Inhibits Inflammation Blood. 112: 694-694. DOI: 10.1182/Blood.V112.11.694.694  0.759
2008 Na I, Lu SX, Goldberg GL, Hirschhorn-Cymerman DD, King CG, Smith OM, Suh D, Rao U, Yim N, Holland AM, Penack O, Jenq RR, Ghosh A, Teisch L, Meykler S, et al. The T Cell Cytolytic Molecules Fas Ligand and TRAIL, the Trafficking Molecules CCR9, β7 Integrin and PSGL-1, and the Immune Modulating Molecules OX40, CEACAM1, and CTLA4 Are Required for Thymic Graft-Versus-Host Disease Blood. 112: 65-65. DOI: 10.1182/Blood.V112.11.65.65  0.785
2008 Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg G, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, Sadelain M, et al. 344: Off-the-Shelf Tumor Immunotherapy with Genetically Enhanced Allogeneic T-Cell Precursors Biology of Blood and Marrow Transplantation. 14: 126. DOI: 10.1016/J.Bbmt.2007.12.354  0.714
2007 Zakrzewski JL, Holland AM, Brink MRMvd. Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation. Journal of Molecular Medicine. 85: 837-843. PMID 17333096 DOI: 10.1007/S00109-007-0175-4  0.571
2007 Zakrzewski JL, Suh D, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Lu SX, Cabrera-Perez J, Rizzuto G, Sant’Angelo DB, van den Brink MR, Markley JC, Riviere I, et al. Targeted ‘Off-the-Shelf’ Tumor Immunotherapy Using Allogeneic T-Cell Precursors. Blood. 110: 579-579. DOI: 10.1182/Blood.V110.11.579.579  0.771
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