Ivan P. Maillard - Publications

Affiliations: 
Immunology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Immunology, Cell Biology

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schneider M, Allman A, Maillard I. Regulation of immune cell development, differentiation and function by stromal Notch ligands. Current Opinion in Cell Biology. 85: 102256. PMID 37806295 DOI: 10.1016/j.ceb.2023.102256  0.38
2023 Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, John Wherry E, Sidoli S, ... Maillard I, et al. Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity. Nature Immunology. PMID 37592014 DOI: 10.1038/s41590-023-01599-7  0.402
2023 Brandstadter JD, Outen R, Maillard I. Having it both ways: how STAT3 deficiency blocks graft-versus-host disease while preserving graft-versus-leukemia activity. The Journal of Clinical Investigation. 133. PMID 37526083 DOI: 10.1172/JCI172251  0.362
2023 Tkachev V, Vanderbeck A, Perkey E, Furlan SN, McGuckin C, Gómez Atria D, Gerdemann U, Rui X, Lane J, Hunt DJ, Zheng H, Colonna L, Hoffman M, Yu A, Outen R, ... ... Maillard I, et al. Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates. Science Translational Medicine. 15: eadd1175. PMID 37379368 DOI: 10.1126/scitranslmed.add1175  0.555
2023 De Martin A, Stanossek Y, Lütge M, Cadosch N, Onder L, Cheng HW, Brandstadter JD, Maillard I, Stoeckli SJ, Pikor NB, Ludewig B. PI16 reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial niches. Nature Immunology. PMID 37202490 DOI: 10.1038/s41590-023-01502-4  0.391
2023 Larson JH, Jin S, Loschi M, Wagers SB, Thangavelu G, Zaiken MC, McDonald-Hyman C, Saha A, Aguilar EG, Koehn B, Osborn MJ, Panoskaltsis-Mortari A, Macdonald KPA, Hill GR, Murphy WJ, ... ... Maillard I, et al. Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 36878433 DOI: 10.1016/j.ajt.2023.01.030  0.434
2022 Schneider M, Maillard I. Bumping CAR T cells up a Notch. Blood. 140: 2185-2186. PMID 36422861 DOI: 10.1182/blood.2022017055  0.459
2022 Gao X, Wang C, Abdelrahman S, Kady N, Murga-Zamalloa C, Gann P, Sverdlov M, Wolfe A, Polk A, Brown N, Bailey NG, Inamdar K, Casavilca-Zambrano S, Montes J, Barrionuevo C, ... ... Maillard I, et al. Notch signaling promotes mature T-cell lymphomagenesis. Cancer Research. PMID 36006995 DOI: 10.1158/0008-5472.CAN-22-1215  0.5
2022 Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, ... ... Maillard I, et al. Retinoic acid signaling acts as a rheostat to balance Treg function. Cellular & Molecular Immunology. PMID 35581350 DOI: 10.1038/s41423-022-00869-y  0.387
2022 Gómez Atria D, Gaudette BT, Londregan J, Kelly S, Perkey E, Allman A, Srivastava B, Koch U, Radtke F, Ludewig B, Siebel CW, Ryan RJ, Robertson TF, Burkhardt JK, Pear WS, ... ... Maillard I, et al. Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naïve B cells. The Journal of Clinical Investigation. PMID 35579963 DOI: 10.1172/JCI158885  0.377
2022 Zaiken MC, Flynn R, Paz KG, Rhee SY, Jin S, Mohamed FA, Saha A, Thangavelu G, Park PMC, Hemming ML, Sage PT, Sharpe AH, DuPage M, Bluestone JA, Panoskaltsis-Mortari A, ... ... Maillard I, et al. BET-bromodomain and EZH2 inhibitor treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes. Blood. PMID 35226736 DOI: 10.1182/blood.2021014557  0.344
2021 Gaudette BT, Roman CJ, Ochoa TA, Gómez Atria D, Jones DD, Siebel CW, Maillard I, Allman D. Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation. The Journal of Clinical Investigation. PMID 34473651 DOI: 10.1172/JCI151975  0.363
2021 Allen F, Maillard I. Therapeutic Targeting of Notch Signaling: From Cancer to Inflammatory Disorders. Frontiers in Cell and Developmental Biology. 9: 649205. PMID 34124039 DOI: 10.3389/fcell.2021.649205  0.368
2021 Serrano-Lopez J, Hegde S, Kumar S, Serrano J, Fang J, Wellendorf AM, Roche PA, Rangel Y, Carrington LJ, Geiger H, Grimes HL, Luther S, Maillard I, Sanchez-Garcia J, Starczynowski DT, et al. Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics. Elife. 10. PMID 33830019 DOI: 10.7554/eLife.66190  0.319
2021 Robertson TF, Chengappa P, Gomez Atria D, Wu CF, Avery L, Roy NH, Maillard I, Petrie RJ, Burkhardt JK. Lymphocyte egress signal sphingosine-1-phosphate promotes ERM-guided, bleb-based migration. The Journal of Cell Biology. 220. PMID 33764397 DOI: 10.1083/jcb.202007182  0.338
2021 Huang A, Bange E, Han N, Wileyto EP, Kim J, Gouma S, Robinson J, Greenplate A, Porterfield F, Owoyemi O, Naik K, Zheng C, Galantino M, Weisman A, Ittner C, ... ... Maillard I, et al. CD8 T cells compensate for impaired humoral immunity in COVID-19 patients with hematologic cancer. Research Square. PMID 33564756 DOI: 10.21203/rs.3.rs-162289/v1  0.315
2021 Grigsby SM, Friedman A, Chase J, Waas B, Ropa J, Serio J, Shen C, Muntean AG, Maillard I, Nikolovska-Coleska Z. Elucidating the Importance of DOT1L Recruitment in MLL-AF9 Leukemia and Hematopoiesis. Cancers. 13. PMID 33562706 DOI: 10.3390/cancers13040642  0.309
2021 Jia W, Poe JC, Su H, Anand S, Matsushima GK, Rathmell JC, Maillard I, Radojcic V, Imai K, Reyes NJ, Cardona DM, Li Z, Suthers A, Curry-Chisolm I, DiCioccio RA, et al. BAFF Promotes Heightened BCR Responsiveness and Manifestations of Chronic GVHD after Allogeneic Stem Cell Transplantation. Blood. PMID 33534893 DOI: 10.1182/blood.2020008040  0.439
2021 Wang L, Yu S, Chan ER, Chen KY, Liu C, Che D, Awadallah A, Myers J, Askew D, Huang AY, Maillard I, Huang D, Xin W, Zhou L. Notch-regulated Dendritic Cells Restrain Inflammation-associated Colorectal Carcinogenesis. Cancer Immunology Research. PMID 33441309 DOI: 10.1158/2326-6066.CIR-20-0428  0.377
2020 Thangavelu G, Wang C, Loschi M, Saha A, Osborn M, Furlan SN, Aoyama K, McDonald-Hyman C, Aguilar EG, Janesick AS, Chandraratna RA, Refaeli Y, Panoskaltsis-Mortari A, MacDonald KP, Hill GR, ... ... Maillard I, et al. Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses. Blood. PMID 32976550 DOI: 10.1182/blood.2020005628  0.496
2020 Parker KR, Migliorini D, Perkey E, Yost KE, Bhaduri A, Bagga P, Haris M, Wilson NE, Liu F, Gabunia K, Scholler J, Montine TJ, Bhoj VG, Reddy R, Mohan S, ... Maillard I, et al. Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies. Cell. PMID 32961131 DOI: 10.1016/J.Cell.2020.08.022  0.484
2020 Vanderbeck A, Maillard I. Notch signaling at the crossroads of innate and adaptive immunity Journal of Leukocyte Biology. 109: 535-548. PMID 32557824 DOI: 10.1002/Jlb.1Ri0520-138R  0.546
2020 Carrington LJ, Maillard I. One-two punch injury to tolerance mechanisms in graft-versus-host disease. Journal of Clinical Investigation. 130: 1625-1628. PMID 32149731 DOI: 10.1172/Jci136139  0.468
2020 Perkey E, Maurice De Sousa D, Carrington L, Chung J, Dils A, Granadier D, Koch U, Radtke F, Ludewig B, Blazar BR, Siebel CW, Brennan TV, Nolz J, Labrecque N, Maillard I. GCNT1-Mediated -Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32060138 DOI: 10.4049/Jimmunol.1901194  0.627
2020 Gómez Atria D, Gaudette BT, Perkey E, Londregan J, Kelly S, Ludewig B, Siebel C, Ryan RJH, Pear WS, Allman D, Maillard I. Stromal Notch Ligands Drive Notch2-Dependent Transdifferentiation of Follicular B Cells into Marginal Zone-like B Cells in Lymphopenic Environments Blood. 136: 38-39. DOI: 10.1182/BLOOD-2020-142474  0.433
2020 Wang L, Yu S, Liu C, Wang W, Che D, Li L, Myers J, Askew D, Chan ER, Huang A, Maillard I, Ivanov I, Xin W, Zhou L. Sa1159 NOTCH2 SIGNALING REGULATES DENDRITIC CELLS TO LIMIT INFLAMMATION-ASSOCIATED COLON CARCINOGENESIS Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)31431-1  0.429
2019 Klossowski S, Miao H, Kempinska K, Wu T, Purohit T, Kim E, Linhares BM, Chen D, Jih G, Perkey E, Huang H, He M, Wen B, Wang Y, Yu K, ... ... Maillard I, et al. Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. The Journal of Clinical Investigation. PMID 31855575 DOI: 10.1172/JCI129126  0.336
2019 Thangavelu G, Du J, Paz KG, Loschi M, Zaiken MC, Flynn R, Taylor PA, Kirchmeier AK, Panoskaltsis-Mortari A, Luznik L, MacDonald KP, Hill GR, Maillard I, Munn DH, Serody JS, et al. Inhibition of Inositol kinase B controls acute and chronic graft-versus-host disease. Blood. PMID 31697815 DOI: 10.1182/Blood.2019000032  0.518
2019 Brandstadter JD, Maillard I. Notch signalling in T cell homeostasis and differentiation. Open Biology. 9: 190187. PMID 31690218 DOI: 10.1098/Rsob.190187  0.554
2019 Vanderbeck AN, Maillard I. Notch in the niche: new insights into the role of Notch signaling in the bone marrow. Haematologica. 104: 2117-2119. PMID 31666339 DOI: 10.3324/Haematol.2019.230854  0.458
2019 Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, et al. Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. Jci Insight. 4. PMID 31578305 DOI: 10.1172/Jci.Insight.127716  0.471
2019 D'Souza SS, Shen X, Fung ITH, Ye L, Kuentzel M, Chittur SV, Furuya Y, Siebel CW, Maillard IP, Metzger DW, Yang Q. Compartmentalized effects of aging on group 2 innate lymphoid cell development and function. Aging Cell. e13019. PMID 31429526 DOI: 10.1111/Acel.13019  0.325
2019 Chung J, Radojcic V, Perkey E, Parnell TJ, Niknafs Y, Jin X, Friedman A, Labrecque N, Blazar BR, Brennan TV, Siebel CW, Maillard I. Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4 T Cells in Graft-versus-Host Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 31182480 DOI: 10.4049/Jimmunol.1900192  0.636
2019 Saha N, Ropa J, Chen L, Hu H, Mysliwski M, Friedman A, Maillard I, Muntean AG. The PAF1c Subunit CDC73 Is Required for Mouse Hematopoietic Stem Cell Maintenance but Displays Leukemia-Specific Gene Regulation. Stem Cell Reports. PMID 31031188 DOI: 10.1016/J.Stemcr.2019.03.010  0.46
2019 Paz K, Flynn R, Du J, Tannheimer S, Johnson AJ, Dong S, Stark AK, Okkenhaug K, Panoskaltsis-Mortari A, Sage PT, Sharpe AH, Luznik L, Ritz J, Soiffer RJ, Cutler CS, ... ... Maillard I, et al. Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30748099 DOI: 10.1111/Ajt.15305  0.565
2019 Brandstadter JD, Perkey E, Gaudette BT, Carrington L, Gomez-Atria D, Blazar BR, Ludewig B, Tikhonova A, Aifantis I, Allman D, Maillard I. Dll1 and Dll4 Notch Ligands Prime T Cell Alloimmunity and Are Expressed in Non-Overlapping Populations of Fibroblastic Stromal Cells in Spleen and Lymph Nodes at the Onset of Gvhd Blood. 134: 588-588. DOI: 10.1182/Blood-2019-123533  0.548
2019 Muntean AG, Ropa J, SAHA N, Hu H, Serio J, Zhao L, Basrur V, Nesvizhskii A, Maillard I. SETDB1 Mediated H3K9 Methylation Suppresses MLL-Fusion Target Expression and Leukemic Transformation Blood. 134: 110-110. DOI: 10.1182/Blood-2019-122610  0.469
2019 Maillard I. From Graft-Versus-Host Disease to Lymphoma Pathogenesis: Emerging Roles for Stromal Notch Ligands in Hematology Blood. 134. DOI: 10.1182/Blood-2019-121067  0.332
2018 Paz K, Flynn R, Du J, Qi J, Luznik L, Maillard I, MacDonald KP, Hill GR, Serody JS, Murphy WJ, Sage PT, Sharpe AH, Miklos D, Culter CS, Koreth J, et al. Small-molecule BCL6 inhibitor effectively treats mice with non-sclerodermatous chronic graft-versus-host disease. Blood. PMID 30279226 DOI: 10.1182/Blood-2018-03-839993  0.485
2018 Radojcic V, Paz K, Chung J, Du J, Perkey ET, Flynn R, Ivcevic S, Zaiken M, Friedman A, Yan M, Pletneva MA, Sarantopoulos S, Siebel CW, Blazar BR, Maillard I. Notch signaling mediated by Delta-like1/4 ligands controls the pathogenesis of chronic graft-versus-host disease in mice. Blood. PMID 30181175 DOI: 10.1182/Blood-2018-03-841155  0.584
2018 Wang Q, Yan R, Pinnell N, McCarter AC, Oh Y, Liu Y, Sha C, Garber NF, Chen Y, Wu Q, Ku CJ, Tran I, Serna Alarcon A, Kuick R, Engel JD, ... Maillard I, et al. Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. Blood. PMID 30076146 DOI: 10.1182/Blood-2018-02-835850  0.571
2018 Ting HA, de Almeida Nagata D, Rasky AJ, Malinczak CA, Maillard IP, Schaller MA, Lukacs NW. Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection. Mucosal Immunology. PMID 30038214 DOI: 10.1038/S41385-018-0052-1  0.54
2018 Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, Kim DI, Emont MP, Zestos AG, Cho JS, Liu J, Kennedy RT, Maillard I, Xu XZS, Wu J. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nature Medicine. PMID 29785025 DOI: 10.1038/S41591-018-0032-8  0.336
2018 Maillard I, Pear WS. Can genetics resolve what Notch does in HSCs? Blood. 131: 1633-1635. PMID 29650730 DOI: 10.1182/Blood-2018-02-829069  0.418
2018 Perkey E, Maillard I. New Insights into Graft-Versus-Host Disease and Graft Rejection Annual Review of Pathology-Mechanisms of Disease. 13: 219-245. PMID 29099650 DOI: 10.1146/Annurev-Pathol-020117-043720  0.485
2018 SAHA N, Ropa J, Chen L, Hu H, Mysliwski M, Friedman A, Maillard I, Muntean AG. The PAF1c Subunit Cdc73 Is Essential for Hematopoiesis and Displays Differential Gene Regulation in MLL-AF9 Driven Leukemia Blood. 132: 1280-1280. DOI: 10.1182/Blood-2018-99-118703  0.472
2018 Jih G, Chase J, Zhou Y, Friedman A, Feng X, Nakayama M, Koseki H, Nishioka K, Huang G, Maillard I. The Trithorax-Group Protein ASH1L Regulates Hematopoietic Stem Cell Homeostasis Independently of Its Histone Methyltransferase Activity Blood. 132: 1270-1270. DOI: 10.1182/Blood-2018-99-117367  0.372
2018 Perkey E, Carrington L, Chung J, Granadier D, Dils A, Friedman A, Tikhonova A, Blazar BR, Koch U, Labrecque N, Radtke F, Siebel C, Aifantis I, Maillard I. Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease Blood. 132: 810-810. DOI: 10.1182/Blood-2018-99-110258  0.605
2018 Tkachev V, Kuhnert F, Furlan SN, Zheng H, Hunt DJ, Colonna L, Carlson JM, Taraseviciute A, Panoskaltsis-Mortari A, Hoglund V, Betz K, Yu A, Blazar BR, Carpenter S, Harari O, ... ... Maillard I, et al. Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates Blood. 132: 2027-2027. DOI: 10.1182/Blood-2018-99-110030  0.602
2018 Grigsby SM, Chase J, Waas B, Friedman A, Du L, Yao A, Ropa J, Serio J, Muntean A, Maillard I, Sun H, Nikolovska-Coleska Z. Abstract 1380: Towards peptidomimetics to target DOT1L recruitment in MLL-AF9 leukemia Cancer Research. 78: 1380-1380. DOI: 10.1158/1538-7445.Am2018-1380  0.303
2017 Srinivasan SR, Cesa LC, Li X, Julien O, Zhuang M, Shao H, Chung J, Maillard I, Wells JA, Duckett C, Gestwicki JE. Heat Shock Protein 70 (Hsp70) Suppresses RIP1-dependent Apoptotic and Necroptotic Cascades. Molecular Cancer Research : McR. PMID 28970360 DOI: 10.1158/1541-7786.Mcr-17-0408  0.314
2017 Poe JC, Jia W, Su H, Anand S, Rose JJ, Tata PV, Suthers AN, Jones CD, Kuan PF, Vincent BG, Serody JS, Horwitz ME, Ho VT, Pavletic SZ, Hakim FT, ... ... Maillard I, et al. An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD. Blood. PMID 28851699 DOI: 10.1182/Blood-2017-05-782466  0.483
2017 Kimball AS, Joshi AD, Boniakowski AE, Schaller M, Chung J, Allen R, Bermick J, Carson WF, Henke PK, Maillard I, Kunkel SL, Gallagher KA. Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing. Frontiers in Immunology. 8: 635. PMID 28620387 DOI: 10.3389/Fimmu.2017.00635  0.324
2017 Neal LM, Qiu Y, Chung J, Xing E, Cho W, Malachowski AN, Sandy-Sloat AR, Osterholzer JJ, Maillard I, Olszewski MA. T Cell-Restricted Notch Signaling Contributes to Pulmonary Th1 and Th2 Immunity during Cryptococcus neoformans Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28615417 DOI: 10.4049/Jimmunol.1601715  0.563
2017 Waas B, Maillard I. Fetal hematopoietic stem cells are making waves. Stem Cell Investigation. 4: 25-25. PMID 28447040 DOI: 10.21037/Sci.2017.03.06  0.471
2017 Ku CJ, Sekiguchi JM, Panwar B, Guan Y, Takahashi S, Yoh K, Maillard I, Hosoya T, Engel JD. GATA3 abundance is a critical determinant of T cell receptor beta allelic exclusion. Molecular and Cellular Biology. PMID 28320875 DOI: 10.1128/Mcb.00052-17  0.425
2017 Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, ... ... Maillard I, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. The Journal of Clinical Investigation. PMID 28319044 DOI: 10.1172/Jci89535  0.632
2017 Du J, Paz K, Flynn R, Vulic A, Robinson TM, Lineburg KE, Alexander KA, Meng J, Roy S, Panoskaltsis-Mortari A, Loschi M, Hill GR, Serody JS, Maillard I, Miklos D, et al. Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production. Blood. PMID 28254742 DOI: 10.1182/Blood-2017-01-758854  0.424
2017 Valls E, Lobry C, Geng H, Wang L, Cardenas M, Rivas M, Cerchietti L, Oh P, Yang SN, Oswald E, Graham CW, Jiang Y, Hatzi K, Agirre X, Perkey E, ... ... Maillard I, et al. BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells. Cancer Discovery. PMID 28232365 DOI: 10.1158/2159-8290.Cd-16-1189  0.454
2017 Zhang K, Xu X, Asghar Pasha M, Siebel CW, Costello A, Haczku A, MacNamara K, Liang T, Zhu J, Bhandoola A, Maillard I, Yang Q. Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28115527 DOI: 10.4049/Jimmunol.1601421  0.41
2017 Ting HA, Schaller MA, de Almeida Nagata DE, Rasky AJ, Maillard IP, Lukacs NW. Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28077598 DOI: 10.4049/Jimmunol.1601654  0.508
2016 Murakami N, Maillard I, Riella LV. Notch Signaling and Immune Regulation in Alloimmunity Current Transplantation Reports. 3: 294-302. PMID 29977738 DOI: 10.1007/S40472-016-0126-5  0.511
2016 Radojcic V, Maillard I. Notch Signaling and Alloreactivity. Transplantation. 100: 2593-2600. PMID 27607530 DOI: 10.1097/Tp.0000000000001468  0.527
2016 McDonald-Hyman C, Flynn R, Panoskaltsis-Mortari A, Peterson N, MacDonald KP, Hill GR, Luznik L, Serody JS, Murphy WJ, Maillard I, Munn DH, Turka LA, Koreth J, Cutler CS, Soiffer RJ, et al. Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5 dependent manner. Blood. PMID 27385791 DOI: 10.1182/Blood-2016-05-715896  0.469
2016 Khoriaty R, Everett L, Chase J, Zhu G, Hoenerhoff M, McKnight B, Vasievich MP, Zhang B, Tomberg K, Williams J, Maillard I, Ginsburg D. Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice. Scientific Reports. 6: 27802. PMID 27297878 DOI: 10.1038/Srep27802  0.319
2016 Chiang MY, Radojcic V, Maillard I. Oncogenic Notch signaling in T-cell and B-cell lymphoproliferative disorders. Current Opinion in Hematology. PMID 27135981 DOI: 10.1097/Moh.0000000000000254  0.533
2016 Jones M, Bisht K, Savage SA, Nandakumar J, Keegan CE, Maillard I. The shelterin complex and hematopoiesis. The Journal of Clinical Investigation. 126: 1621-9. PMID 27135879 DOI: 10.1172/Jci84547  0.309
2016 Chung J, Riella LV, Maillard I. Targeting the Notch pathway to prevent rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27037759 DOI: 10.1111/Ajt.13816  0.552
2016 Flynn R, Paz K, Du J, Reichenbach DK, Taylor PA, Panoskaltsis-Mortari A, Vulic A, Luznik L, MacDonald KK, Hill GR, Nyuydzefe MS, Weiss JM, Chen W, Trzeciak A, Serody JS, ... ... Maillard I, et al. Targeted Rho-associated kinase 2 (ROCK2) inhibition decreases clinical and immune pathology of murine and human chronic GVHD through Stat3-dependent mechanism. Blood. PMID 26983850 DOI: 10.1182/Blood-2015-10-678706  0.46
2016 Radojcic V, Flynn RP, Chung J, Du J, Perkey E, Paz K, Zaiken M, Friedman A, Yan M, Siebel CW, Blazar BR, Maillard I. Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease Blood. 128: 805-805. DOI: 10.1182/Blood.V128.22.805.805  0.639
2016 Poe JC, Jia W, Su H, Li Z, Hakim FT, Pavletic SZ, Rose JJ, Rizzieri DA, Yang Y, Chen BJ, Anand S, Ritz J, Siebel CW, Chao NJ, Maillard I, et al. All-Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients Blood. 128: 669-669. DOI: 10.1182/Blood.V128.22.669.669  0.467
2016 Wang Q, Yan R, Pinnell N, Liu Y, Alarcon AS, Qin J, Chen Y, Kim E, Garber N, Maillard I, Cierpicki T, Chiang M. The Direct Notch1 Cofactor Zmiz1 Differentially Regulates Notch1 Signals in a Stage-Specific Manner to Preserve Early T-Cell Precursors and Expand Committed T Cells Blood. 128: 426-426. DOI: 10.1182/Blood.V128.22.426.426  0.612
2016 Du J, Flynn RP, Paz K, Vulic A, Robinson TM, Lineburg KE, Macdonald KPA, Hill GR, Serody JS, Maillard I, Panoskaltsis-Mortari A, Schacker T, Luznik L, Blazar BR. Pirfenidone Reverses Murine Chronic Graft Versus Host Disease Blood. 128: 1158-1158. DOI: 10.1182/Blood.V128.22.1158.1158  0.417
2016 Grigsby S, Chase J, Ropa J, Serio J, Shen C, Larsen M, Donover P, Reichman M, Muntean A, Maillard I, Nikolovska-Coleska Z. Abstract 3803: Development of genetic and chemical tools for understanding the recruitment of DOT1L in MLL-fusion driven leukemia and normal hematopoiesis Cancer Research. 76: 3803-3803. DOI: 10.1158/1538-7445.Am2016-3803  0.343
2015 Maillard I, Saltiel AR. Metabolism: Inflammation keeps old mice healthy. Nature. PMID 26580010 DOI: 10.1038/Nature15648  0.331
2015 Pinnell N, Yan R, Cho HJ, Keeley T, Murai MJ, Liu Y, Alarcon AS, Qin J, Wang Q, Kuick R, Elenitoba-Johnson KS, Maillard I, Samuelson LC, Cierpicki T, Chiang MY. The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia. Immunity. PMID 26522984 DOI: 10.1016/J.Immuni.2015.10.007  0.561
2015 Ku CJ, Lim KC, Kalantry S, Maillard I, Engel JD, Hosoya T. A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance. Genes & Development. 29: 1930-41. PMID 26385963 DOI: 10.1101/Gad.265025.115  0.521
2015 Chase J, Grembecka J, Maillard I. Trithorax group genes in hematopoiesis. Oncotarget. 6: 17855-6. PMID 26257003 DOI: 10.18632/Oncotarget.4882  0.434
2015 Lubeck BA, Lapinski PE, Oliver JA, Ksionda O, Parada LF, Zhu Y, Maillard I, Chiang M, Roose J, King PD. Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia. Journal of Immunology (Baltimore, Md. : 1950). 195: 31-5. PMID 26002977 DOI: 10.4049/Jimmunol.1402639  0.553
2015 Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T, Dou Y, Camper SA, Maillard I. Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells. The Journal of Clinical Investigation. 125: 2007-20. PMID 25866973 DOI: 10.1172/Jci78124  0.41
2015 Flynn R, Allen JL, Luznik L, MacDonald KP, Paz K, Alexander KA, Vulic A, Du J, Panoskaltsis-Mortari A, Taylor PA, Poe JC, Serody JS, Murphy WJ, Hill GR, Maillard I, et al. Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood. 125: 4085-94. PMID 25852057 DOI: 10.1182/Blood-2014-08-595470  0.501
2015 Carulli AJ, Keeley TM, Demitrack ES, Chung J, Maillard I, Samuelson LC. Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration. Developmental Biology. 402: 98-108. PMID 25835502 DOI: 10.1016/J.Ydbio.2015.03.012  0.506
2015 Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, ... ... Maillard I, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 27: 589-602. PMID 25817203 DOI: 10.1016/J.Ccell.2015.02.016  0.338
2015 Wood S, Feng J, Chung J, Radojcic V, Sandy-Sloat AR, Friedman A, Shelton A, Yan M, Siebel CW, Bishop DK, Maillard I. Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2899-908. PMID 25687759 DOI: 10.4049/Jimmunol.1402034  0.56
2015 Brown NA, Ross CW, Gudjonsson JE, Wale D, Pawarode A, Maillard I, Hristov AC. Subcutaneous panniculitis-like T-cell lymphoma with bone marrow involvement. American Journal of Clinical Pathology. 143: 265-73. PMID 25596253 DOI: 10.1309/Ajcpvzyb19Nedxxz  0.41
2015 Khoriaty R, Everett L, Chase J, Zhu G, Zhang B, Hoenerhoff M, Maillard I, Ginsburg D. SEC23A Functionally Compensates for SEC23B Deficiency in Mice Blood. 126: 935-935. DOI: 10.1182/Blood.V126.23.935.935  0.355
2015 Poe JC, Jia W, Li Z, Hakim FT, Pavletic SZ, Rose JJ, Rizzieri DA, Yang Y, Chen BJ, Green M, Anand S, Siebel CW, Maillard I, Chao NJ, Sarantopoulos S. Targeting the Human Notch 2-BCR Axis: A Driver of B-Cell Hyper-Responsiveness in Active Chronic Graft-Versus Host Disease (cGVHD) Blood. 126: 145-145. DOI: 10.1182/Blood.V126.23.145.145  0.495
2015 Radojcic V, Chung J, Friedman A, Reddy P, Blazar BR, Luznik L, Brennan T, Siebel C, Maillard I. Early Post-Transplant Notch Signaling Activity Is Critical for the Differentiation of Pathogenic Alloantigen-Specific T Cells Mediating Acute Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 21. DOI: 10.1016/J.Bbmt.2014.11.553  0.349
2014 Thomas MM, Zhang Y, Mathew E, Kane KT, Maillard I, Pasca di Magliano M. Epithelial Notch signaling is a limiting step for pancreatic carcinogenesis. Bmc Cancer. 14: 862. PMID 25416148 DOI: 10.1186/1471-2407-14-862  0.418
2014 Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, ... ... Maillard I, et al. Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. The Journal of Clinical Investigation. 124: 4867-76. PMID 25271622 DOI: 10.1172/Jci75328  0.566
2014 Khoriaty R, Vasievich MP, Jones M, Everett L, Chase J, Tao J, Siemieniak D, Zhang B, Maillard I, Ginsburg D. Absence of a red blood cell phenotype in mice with hematopoietic deficiency of SEC23B. Molecular and Cellular Biology. 34: 3721-34. PMID 25071156 DOI: 10.1128/Mcb.00287-14  0.396
2014 Tsai YH, VanDussen KL, Sawey ET, Wade AW, Kasper C, Rakshit S, Bhatt RG, Stoeck A, Maillard I, Crawford HC, Samuelson LC, Dempsey PJ. ADAM10 regulates Notch function in intestinal stem cells of mice. Gastroenterology. 147: 822-834.e13. PMID 25038433 DOI: 10.1053/J.Gastro.2014.07.003  0.479
2014 Wu ZQ, Rowe RG, Lim KC, Lin Y, Willis A, Tang Y, Li XY, Nor JE, Maillard I, Weiss SJ. A Snail1/Notch1 signalling axis controls embryonic vascular development. Nature Communications. 5: 3998. PMID 24894949 DOI: 10.1038/Ncomms4998  0.391
2014 Flynn R, Du J, Veenstra RG, Reichenbach DK, Panoskaltsis-Mortari A, Taylor PA, Freeman GJ, Serody JS, Murphy WJ, Munn DH, Sarantopoulos S, Luznik L, Maillard I, Koreth J, Cutler C, et al. Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood. 123: 3988-98. PMID 24820310 DOI: 10.1182/Blood-2014-03-562231  0.559
2014 Radojcic V, Maillard I. A Jagged Road to Lymphoma Aggressiveness Cancer Cell. 25: 261-263. PMID 24651005 DOI: 10.1016/J.Ccr.2014.03.001  0.44
2014 Maillard I. Notch and human hematopoietic stem cells. Blood. 123: 1115-1116. PMID 24558186 DOI: 10.1182/Blood-2014-01-546754  0.456
2014 Mukherjee S, Rasky AJ, Lundy PA, Kittan NA, Kunkel SL, Maillard IP, Kowalski PE, Kousis PC, Guidos CJ, Lukacs NW. STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease. Journal of Immunology (Baltimore, Md. : 1950). 192: 996-1003. PMID 24367028 DOI: 10.4049/Jimmunol.1301991  0.461
2014 Jones M, Osawa G, Regal JA, Weinberg DN, Taggart J, Kocak H, Friedman A, Ferguson DO, Keegan CE, Maillard I. Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation. The Journal of Clinical Investigation. 124: 353-66. PMID 24316971 DOI: 10.1172/Jci67871  0.451
2014 Chung J, Ebens CL, Radojcic V, Koch U, Friedman A, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Ludewig B, Siebel CW, Radtke F, Maillard I. Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease Blood. 124: 841-841. DOI: 10.1182/Blood.V124.21.841.841  0.623
2014 Pinnell N, Yan R, Cho H, Jeon P, Keeley T, McHugh J, Liu Y, Elenitoba-Johnson KS, Maillard I, Samuelson LC, Cierpicki T, Chiang MY. Direct Coregulation of Notch1 By Zmiz1 in T-Cell Development and Leukemia Blood. 124: 55-55. DOI: 10.1182/Blood.V124.21.55.55  0.597
2014 Flynn RP, Goodman K, Qi J, Jing D, Panoskaltsis-Mortari A, Yi Z, Dong C, Liu X, MacDonald KPA, Hill GR, Serody JS, Murphy WJ, Luznik L, Maillard I, Koreth J, et al. Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies Blood. 124: 535-535. DOI: 10.1182/Blood.V124.21.535.535  0.558
2014 Khoriaty R, Vasievich M, Jones M, Chase J, Everett L, Zhang B, Maillard I, Ginsburg D. SEC23B Deficiency Results in Different Phenotypes in Humans and Mice Blood. 124: 1341-1341. DOI: 10.1182/Blood.V124.21.1341.1341  0.379
2014 Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Yang C, Towns W, Lehman A, Johnson A, Devine S, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, ... ... Maillard I, et al. Abstract 2591: Ibrutinib can reverse established chronic graft-versus-host disease, which is dependent upon IL-2 inducible T-cell kinase (ITK) and Bruton's tyrosine kinase (BTK)-driven lymphocyte activation Cancer Research. 74: 2591-2591. DOI: 10.1158/1538-7445.Am2014-2591  0.511
2014 Chase J, Jones M, Brinkmeier M, Friedman A, Camper S, Maillard I. The Trithorax group gene Ash1l regulates quiescence, self-renewal potential and niche occupancy in adult hematopoietic stem cells Experimental Hematology. 42: S28. DOI: 10.1016/J.Exphem.2014.07.100  0.349
2013 Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY. Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development (Cambridge, England). 140: 4870-80. PMID 24198274 DOI: 10.1242/Dev.101725  0.372
2013 Ebens CL, Maillard I. Notch signaling in hematopoietic cell transplantation and T cell alloimmunity Blood Reviews. 27: 269-277. PMID 24050990 DOI: 10.1016/J.Blre.2013.08.001  0.625
2013 Muntean AG, Chen W, Jones M, Granowicz EM, Maillard I, Hess JL. MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction. Blood. 122: 1914-22. PMID 23900238 DOI: 10.1182/Blood-2013-02-486977  0.408
2013 Sandy AR, Stoolman J, Malott K, Pongtornpipat P, Segal BM, Maillard I. Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 191: 1606-13. PMID 23825310 DOI: 10.4049/Jimmunol.1301116  0.833
2013 Sandy AR, Chung J, Toubai T, Shan GT, Tran IT, Friedman A, Blackwell TS, Reddy P, King PD, Maillard I. T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 5818-28. PMID 23636056 DOI: 10.4049/Jimmunol.1203452  0.828
2013 Maillard I. Ikaros, Notch, and GATA1 cross paths during megakaryopoiesis. Blood. 121: 2376-2377. PMID 23538229 DOI: 10.1182/Blood-2013-02-480442  0.309
2013 Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I. Blockade of individual Notch ligands and receptors controls graft-versus-host disease. The Journal of Clinical Investigation. 123: 1590-604. PMID 23454750 DOI: 10.1172/Jci65477  0.834
2013 Hassan KA, Wang L, Korkaya H, Chen G, Maillard I, Beer DG, Kalemkerian GP, Wicha MS. Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1972-80. PMID 23444212 DOI: 10.1158/1078-0432.Ccr-12-0370  0.421
2013 Rakowski LA, Garagiola DD, Li CM, Decker M, Caruso S, Jones M, Kuick R, Cierpicki T, Maillard I, Chiang MY. Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias. Cancer Research. 73: 930-41. PMID 23161489 DOI: 10.1158/0008-5472.Can-12-1389  0.527
2013 Maillard I. Ask the Experts: Targeting Notch signaling in graft-versus-host disease International Journal of Hematologic Oncology. 2: 197-202. DOI: 10.2217/Ijh.13.25  0.422
2013 Khoriaty R, Vasievich M, Jones M, Zhang B, Everett L, Tao J, Maillard I, Ginsburg D. Disparate Phenotypes Of SEC23B Deficiency In Humans and Mice Blood. 122: 312-312. DOI: 10.1182/Blood.V122.21.312.312  0.386
2013 Flynn R, Du J, Veenstra R, Panoskaltsis-Mortari A, Price A, Taylor PA, Freeman GJ, Browning JL, Serody J, Murphy WJ, Munn D, Sarantopoulos S, Luznik L, Maillard I, Koreth J, et al. Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model Blood. 122: 292-292. DOI: 10.1182/Blood.V122.21.292.292  0.596
2013 Ebens CL, Chung J, Koch U, Tran IT, Sandy-Sloat AR, Friedman A, Blazar BR, Reddy P, Yan M, Siebel CW, Radtke F, Maillard I. Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation Blood. 122: 2003-2003. DOI: 10.1182/Blood.V122.21.2003.2003  0.563
2012 Chung J, Maillard I. Notch Signaling in Alloreactive T Cell Immunity Current Topics in Microbiology and Immunology. 360: 135-150. PMID 22689203 DOI: 10.1007/82_2012_226  0.544
2012 Sandy AR, Jones M, Maillard I. Notch signaling and development of the hematopoietic system. Advances in Experimental Medicine and Biology. 727: 71-88. PMID 22399340 DOI: 10.1007/978-1-4614-0899-4_6  0.814
2012 Pan X, Jones M, Jiang J, Zaprazna K, Yu D, Pear W, Maillard I, Atchison ML. Increased expression of PcG protein YY1 negatively regulates B cell development while allowing accumulation of myeloid cells and LT-HSC cells. Plos One. 7: e30656. PMID 22292011 DOI: 10.1371/Journal.Pone.0030656  0.474
2012 Ku CJ, Hosoya T, Maillard I, Engel JD. GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry. Blood. 119: 2242-51. PMID 22267605 DOI: 10.1182/Blood-2011-07-366070  0.488
2012 VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud A, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, et al. Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells Development. 139: 488-497. PMID 22190634 DOI: 10.1242/Dev.070763  0.533
2012 Khoriaty R, Vasievich M, Jones M, Everett L, Zhang B, Maillard I, Ginsburg D. Disparate SEC23B Deficient Phenotypes in Humans and Mice Blood. 120: 974-974. DOI: 10.1182/Blood.V120.21.974.974  0.372
2012 Sandy AR, Chung J, Tran IT, Shan GT, Friedman A, Blackwell TS, Reddy P, King PD, Maillard I. Notch Inhibition in Alloreactive CD4+ and CD8+ T Cells Blocks Graft-Versus-Host Disease by Inducing a Hyporesponsive Program with Features of T Cell Anergy Blood. 120: 340-340. DOI: 10.1182/Blood.V120.21.340.340  0.827
2011 Tan J, Jones M, Koseki H, Nakayama M, Muntean AG, Maillard I, Hess JL. CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis. Cancer Cell. 20: 563-75. PMID 22094252 DOI: 10.1016/J.Ccr.2011.09.008  0.311
2011 Aster JC, Bodnar N, Xu L, Karnell F, Milholland JM, Maillard I, Histen G, Nam Y, Blacklow SC, Pear WS. Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation. Plos One. 6: e25645. PMID 22022427 DOI: 10.1371/Journal.Pone.0025645  0.578
2011 Toubai T, Sun Y, Tawara I, Friedman A, Liu C, Evers R, Nieves E, Malter C, Chockley P, Maillard I, Winandy S, Reddy P. Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease. Blood. 118: 192-204. PMID 21471527 DOI: 10.1182/Blood-2010-12-324616  0.524
2011 Jo SY, Granowicz EM, Maillard I, Thomas D, Hess JL. Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation Blood. 117: 4759-4768. PMID 21398221 DOI: 10.1182/Blood-2010-12-327668  0.461
2011 Zhang Y, Sandy AR, Wang J, Radojcic V, Shan GT, Tran IT, Friedman A, Kato K, He S, Cui S, Hexner E, Frank DM, Emerson SG, Pear WS, Maillard I. Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease. Blood. 117: 299-308. PMID 20870902 DOI: 10.1182/Blood-2010-03-271940  0.842
2011 Maillard I. Notch Signaling in Graft-Versus-Host Disease Blood. 118. DOI: 10.1182/Blood.V118.21.Sci-14.Sci-14  0.654
2011 Tran IT, Sandy AR, Carulli A, Shan GT, Radojcic V, Friedman A, Shelton A, Samuelson LC, Yan M, Siebel CW, Maillard I. In Vivo Blockade of Individual Notch Ligands and Receptors Provides a New Targeted Therapeutic Approach In Graft-Versus-Host Disease Blood. 118: 819-819. DOI: 10.1182/Blood.V118.21.819.819  0.835
2011 Jones M, Brinkmeier ML, Schira J, Friedman A, Malek S, Dou Y, Camper SA, Maillard I. The Trithorax Group Protein Ash1l Is An Essential Epigenetic Regulator of Adult Hematopoietic Stem Cell Maintenance Blood. 118: 387-387. DOI: 10.1182/Blood.V118.21.387.387  0.442
2011 Hassan KA, Wang L, Korkaya H, Chen G, Maillard I, Beer D, Kalemkerian GP, Wicha MS. Abstract 496: Notch pathway activity identifies functional lung cancer stem cells and correlates with worse survival in patients with lung adenocarcinoma Cancer Research. 71: 496-496. DOI: 10.1158/1538-7445.Am2011-496  0.451
2010 Hosoya T, Maillard I, Engel JD. From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation. Immunological Reviews. 238: 110-25. PMID 20969588 DOI: 10.1111/J.1600-065X.2010.00954.X  0.577
2010 Jones M, Osawa GA, Friedman A, Luo W, Keegan CE, Maillard I. Hematopoietic Defects In ACD/TPP1-Deficient Mice Reveal An Essential Role for the Shelterin Complex In Blood-Forming Stem Cell Homeostasis Blood. 116: 882-882. DOI: 10.1182/Blood.V116.21.882.882  0.45
2010 Vasievich M, Zhang B, Rinehart J, Jones M, Maillard I, Ginsburg D. Sec23b deficiency In Mice Results In Pancreatic Destruction and Defective long Term Hematopoietic Stem Cell Function Blood. 116: 2038-2038. DOI: 10.1182/Blood.V116.21.2038.2038  0.44
2009 Maillard I, Hess JL. The Role of Menin in Hematopoiesis Advances in Experimental Medicine and Biology. 668: 51-57. PMID 20175452 DOI: 10.1007/978-1-4419-1664-8_5  0.406
2009 Hosoya T, Kuroha T, Moriguchi T, Cummings D, Maillard I, Lim KC, Engel JD. GATA-3 is required for early T lineage progenitor development. The Journal of Experimental Medicine. 206: 2987-3000. PMID 19934022 DOI: 10.1084/Jem.20090934  0.566
2009 Sandy AR, Maillard I. Notch signaling in the hematopoietic system. Expert Opinion On Biological Therapy. 9: 1383-98. PMID 19743891 DOI: 10.1517/14712590903260777  0.822
2009 Lumeng CN, Maillard I, Saltiel AR. T-ing up inflammation in fat. Nature Medicine. 15: 846-7. PMID 19661987 DOI: 10.1038/Nm0809-846  0.328
2009 Maillard I, Chen YX, Friedman A, Yang Y, Tubbs AT, Shestova O, Pear WS, Hua X. Menin regulates the function of hematopoietic stem cells and lymphoid progenitors. Blood. 113: 1661-9. PMID 19228930 DOI: 10.1182/Blood-2008-01-135012  0.43
2009 Toubai T, Sun Y, Tawara I, Malter C, Lowler K, Nieves E, Liu C, Maillard I, Winandy S, Reddy P. Ikaros Deficiency Enhances Notch Signaling in Host Antigen Presenting Cells and Differentially Regulates Gvhd and GVL Responses After Experimental BMT. Blood. 114: 690-690. DOI: 10.1182/Blood.V114.22.690.690  0.463
2009 Shan GT, Tran I, Sandy AR, Friedman A, Zhang Y, Maillard I. Inhibition of Notch Signaling in T Cells Prevents Immune-Mediated Bone Marrow Failure. Blood. 114: 180-180. DOI: 10.1182/Blood.V114.22.180.180  0.84
2008 Mercher T, Cornejo MG, Sears C, Kindler T, Moore SA, Maillard I, Pear WS, Aster JC, Gilliland DG. Notch signaling specifies megakaryocyte development from hematopoietic stem cells. Cell Stem Cell. 3: 314-26. PMID 18786418 DOI: 10.1016/J.Stem.2008.07.010  0.558
2008 Maillard I, Koch U, Dumortier A, Shestova O, Xu L, Sai H, Pross SE, Aster JC, Bhandoola A, Radtke F, Pear WS. Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. Cell Stem Cell. 2: 356-66. PMID 18397755 DOI: 10.1182/Blood.V106.11.267.267  0.504
2008 Guo Y, Maillard I, Chakraborti S, Rothenberg EV, Speck NA. Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification. Blood. 112: 480-92. PMID 18390836 DOI: 10.1182/Blood-2007-10-120261  0.6
2008 Jakubowiak AJ, Hari M, Kendall T, Khaled Y, Mineishi S, Al-Zoubi A, Kaminski MS, Maillard I. Elimination of CD20-Expressing Cells in Multiple Myeloma by Iodine I-131 Tositumomab (Bexxar®) Correlates with Response to Therapy Blood. 112: 5176-5176. DOI: 10.1182/Blood.V112.11.5176.5176  0.424
2008 Cornejo MG, Mercher T, Growney JD, Jesneck J, Maillard I, Pear WS, Aster J, Gilliland DG. Runx1 Is Required for Notch-Induced Specification of Megakaryocyte Development from Early Hematopoietic Stem and Progenitor Cells Blood. 112: 1370-1370. DOI: 10.1182/Blood.V112.11.1370.1370  0.462
2007 Santos MA, Sarmento LM, Rebelo M, Doce AA, Maillard I, Dumortier A, Neves H, Radtke F, Pear WS, Parreira L, Demengeot J. Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 15454-9. PMID 17878313 DOI: 10.1073/Pnas.0702891104  0.503
2007 Wu L, Maillard I, Nakamura M, Pear WS, Griffin JD. The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development. Blood. 110: 3618-23. PMID 17699740 DOI: 10.1182/Blood-2007-06-097030  0.563
2007 Maillard I, Pear WS. Immunology. Keeping a tight leash on Notch. Science (New York, N.Y.). 316: 840-2. PMID 17495159 DOI: 10.1126/Science.1143336  0.557
2007 Zediak VP, Maillard I, Bhandoola A. Multiple prethymic defects underlie age-related loss of T progenitor competence. Blood. 110: 1161-7. PMID 17456721 DOI: 10.1182/Blood-2007-01-071605  0.472
2007 Schwarz BA, Sambandam A, Maillard I, Harman BC, Love PE, Bhandoola A. Selective thymus settling regulated by cytokine and chemokine receptors. Journal of Immunology (Baltimore, Md. : 1950). 178: 2008-17. PMID 17277104 DOI: 10.4049/Jimmunol.178.4.2008  0.522
2007 Thomas M, Calamito M, Srivastava B, Maillard I, Pear WS, Allman D. Notch activity synergizes with B-cell-receptor and CD40 signaling to enhance B-cell activation. Blood. 109: 3342-50. PMID 17179224 DOI: 10.1182/Blood-2006-09-046698  0.486
2007 Talebian L, Li Z, Guo Y, Gaudet J, Speck ME, Sugiyama D, Kaur P, Pear WS, Maillard I, Speck NA. T-lymphoid, megakaryocyte, and granulocyte development are sensitive to decreases in CBFbeta dosage. Blood. 109: 11-21. PMID 16940420 DOI: 10.1182/Blood-2006-05-021188  0.495
2007 Maillard I, Chen Y, Tubbs AT, Shestova O, Pear WS, Hua X. Menin Regulates the Function of Lymphoid Progenitors and Hematopoietic Stem Cells. Blood. 110: 1257-1257. DOI: 10.1182/Blood.V110.11.1257.1257  0.442
2006 Keeshan K, He Y, Wouters BJ, Shestova O, Xu L, Sai H, Rodriguez CG, Maillard I, Tobias JW, Valk P, Carroll M, Aster JC, Delwel R, Pear WS. Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia. Cancer Cell. 10: 401-11. PMID 17097562 DOI: 10.1016/J.Ccr.2006.09.012  0.452
2006 Maillard I, Tu L, Sambandam A, Yashiro-Ohtani Y, Millholland J, Keeshan K, Shestova O, Xu L, Bhandoola A, Pear WS. The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. The Journal of Experimental Medicine. 203: 2239-45. PMID 16966428 DOI: 10.1084/Jem.20061020  0.533
2006 Maillard I, Schwarz BA, Sambandam A, Fang T, Shestova O, Xu L, Bhandoola A, Pear WS. Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation. Blood. 107: 3511-9. PMID 16397133 DOI: 10.1182/Blood-2005-08-3454  0.527
2006 Wu L, Maillard I, Nakamura M, Pear WS, Griffin JD. The MAML1 Transcriptional Co-Activator Is Required for the Development of Marginal Zone B Cells. Blood. 108: 777-777. DOI: 10.1182/Blood.V108.11.777.777  0.499
2006 Keeshan K, He Y, Wouters BJ, Shestova O, Xu L, Sai H, Rodriguez CG, Maillard I, Valk P, Carroll M, Aster JC, Delwel R, Pear WS. Tribbles Homolog 2 (Trib2) Inactivates C/EBPalpha and Causes Acute Myelogenous Leukemia. Blood. 108: 776-776. DOI: 10.1182/Blood.V108.11.776.776  0.401
2006 Maillard I, High F, Shestova O, Dedhia P, Epstein JA, Pear WS. Notch Signaling Regulates Hematopoietic Stem Cell Homeostasis in the Fetal Liver through a Non-Cell-Autonomous Mechanism. Blood. 108: 440-440. DOI: 10.1182/Blood.V108.11.440.440  0.497
2005 Tu L, Fang TC, Artis D, Shestova O, Pross SE, Maillard I, Pear WS. Notch signaling is an important regulator of type 2 immunity. The Journal of Experimental Medicine. 202: 1037-42. PMID 16230473 DOI: 10.1084/Jem.20050923  0.577
2005 Zediak VP, Maillard I, Bhandoola A. Closer to the source: notch and the nature of thymus-settling cells. Immunity. 23: 245-8. PMID 16169497 DOI: 10.1016/J.Immuni.2005.08.008  0.509
2005 Sambandam A, Maillard I, Zediak VP, Xu L, Gerstein RM, Aster JC, Pear WS, Bhandoola A. Notch signaling controls the generation and differentiation of early T lineage progenitors. Nature Immunology. 6: 663-70. PMID 15951813 DOI: 10.1038/Ni1216  0.509
2005 Maillard I, Fang T, Pear WS. Regulation of lymphoid development, differentiation, and function by the Notch pathway. Annual Review of Immunology. 23: 945-74. PMID 15771590 DOI: 10.1146/Annurev.Immunol.23.021704.115747  0.544
2005 Guo Y, Talebian L, Maillard I, Speck CL, Pear WS, Rothenberg EV, Speck NA. Reduction of Core Binding Factor beta (CBFβ) Dosage Blocks T Cell Development. Blood. 106: 2714-2714. DOI: 10.1182/Blood.V106.11.2714.2714  0.565
2005 Maillard I, Talebian L, Li Z, Guo Y, Sugiyama D, Speck ME, Pear WS, Speck NA. A Hypomorphic Cbfb Allele Reveals a Critical Dosage-Sensitive Function of Core Binding Factors at the Earliest Stages of T Cell Development. Blood. 106: 124-124. DOI: 10.1182/Blood.V106.11.124.124  0.548
2005 Sambandam A, Maillard I, Zediak VP, Xu L, Gerstein RM, Aster JC, Pear WS, Bhandoola A. Erratum: Notch signaling controls the generation and differentiation of early T lineage progenitors Nature Immunology. 6: 852-852. DOI: 10.1038/Ni0805-852A  0.475
2004 Maillard I, Weng AP, Carpenter AC, Rodriguez CG, Sai H, Xu L, Allman D, Aster JC, Pear WS. Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. Blood. 104: 1696-702. PMID 15187027 DOI: 10.1182/Blood-2004-02-0514  0.579
2004 Tsai DE, Maillard I, Downs LH, Alavi A, Nasta SD, Glatstein E, Schuster SJ. Use of iodine 131I-tositumomab radioimmunotherapy in a patient with Waldenstrom's macroglobulinemia. Leukemia & Lymphoma. 45: 591-5. PMID 15160923 DOI: 10.1080/10428190310001597946  0.361
2004 Pross S, Millholland JM, Sai H, Weng AP, Aster JC, Pear WS, Maillard I. Efficient Inhibition of Notch3 and Notch4 Family Members In Vivo by a Dominant Negative Mutant of Mastermind. Blood. 104: 1617-1617. DOI: 10.1182/Blood.V104.11.1617.1617  0.602
2004 Maillard I, Sambandan A, Zediak VP, Schwarz B, Xu L, Aster JC, Pear WS, Bhandoola A. Intrathymic and Extrathymic Notch-Dependent T Lineage Checkpoints during Normal Development and after Bone Marrow Transplantation. Blood. 104: 1190-1190. DOI: 10.1182/Blood.V104.11.1190.1190  0.617
2003 Maillard I, Adler SH, Pear WS. Notch and the immune system. Immunity. 19: 781-91. PMID 14670296 DOI: 10.1016/S1074-7613(03)00325-X  0.566
2003 Tsai DE, Maillard I, Schuster SJ, Nasta SD, Porter DL, Klumpp TR, Goldenberg DM, Luger SM, Alavi A, Sharkey RM, Hartzell KB, Stadtmauer EA. Use of ibritumomab tiuxetan anti-CD20 radioimmunotherapy in a non-Hodgkin's lymphoma patient previously treated with a yttrium-90-labeled anti-CD22 monoclonal antibody. Clinical Lymphoma. 4: 56-9. PMID 12837157 DOI: 10.3816/Clm.2003.N.015  0.315
2003 Maillard I, He Y, Pear WS. From the yolk sac to the spleen: New roles for Notch in regulating hematopoiesis. Immunity. 18: 587-9. PMID 12753735 DOI: 10.1016/S1074-7613(03)00119-5  0.54
2003 Maillard I, Pear WS. Notch and cancer: best to avoid the ups and downs. Cancer Cell. 3: 203-5. PMID 12676578 DOI: 10.1016/S1535-6108(03)00052-7  0.36
2002 Allenspach EJ, Maillard I, Aster JC, Pear WS. Notch signaling in cancer. Cancer Biology & Therapy. 1: 466-76. PMID 12496471 DOI: 10.4161/Cbt.1.5.159  0.475
2001 Baribaud F, Wirth S, Maillard I, Valsesia S, Acha-Orbea H, Diggelmann H. Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V(beta) domains. Journal of Virology. 75: 7453-61. PMID 11462017 DOI: 10.1128/Jvi.75.16.7453-7461.2001  0.444
2001 Maillard I, Launois P, Himmelrich H, Acha-Orbea H, Diggelmann H, Locksley RM, Louis JA. Functional plasticity of the LACK-reactive Vbeta4-Valpha8 CD4(+) T cells normally producing the early IL-4 instructing Th2 cell development and susceptibility to Leishmania major in BALB / c mice. European Journal of Immunology. 31: 1288-96. PMID 11298356 DOI: 10.1002/1521-4141(200104)31:4<1288::Aid-Immu1288>3.0.Co;2-8  0.461
2000 Himmelrich H, Launois P, Maillard I, Biedermann T, Tacchini-Cottier F, Locksley RM, Röcken M, Louis JA. In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. Journal of Immunology (Baltimore, Md. : 1950). 164: 4819-25. PMID 10779790 DOI: 10.4049/Jimmunol.164.9.4819  0.366
1999 Baribaud F, Maillard I, Vacheron S, Brocker T, Diggelmann H, Acha-Orbea H. Role of Dendritic Cells in the Immune Response Induced by Mouse Mammary Tumor Virus Superantigen Journal of Virology. 73: 8403-8410. PMID 10482591 DOI: 10.1128/Jvi.73.10.8403-8410.1999  0.508
1998 Maillard I, Xenarios I, Diggelmann H, Orbea HA. Differential reactivity of TCR Vbeta10 alleles to a mouse mammary tumor virus superantigen. European Journal of Immunology. 28: 3075-85. PMID 9808176 DOI: 10.1002/(Sici)1521-4141(199810)28:10<3075::Aid-Immu3075>3.0.Co;2-6  0.421
1998 Maillard I, Launois P, Xenarios I, Louis JA, Acha-Orbea H, Diggelmann H. Immune response to mouse mammary tumor virus in mice lacking the alpha/beta interferon or the gamma interferon receptor. Journal of Virology. 72: 2638-46. PMID 9525580 DOI: 10.1128/Jvi.72.4.2638-2646.1998  0.315
1997 Maillard I, Luthi F, Acha-Orbea H, Diggelmann H. Role of the immune response induced by superantigens in the pathogenesis of microbial infections Parasitology. 115: 67-78. PMID 9571692 DOI: 10.1017/S0031182097001807  0.426
1997 Launois P, Maillard I, Pingel S, Swihart KG, Xénarios I, Acha-Orbea H, Diggelmann H, Locksley RM, MacDonald HR, Louis JA. IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity. 6: 541-9. PMID 9175832 DOI: 10.1016/S1074-7613(00)80342-8  0.399
1996 Maillard I, Erny K, Acha-Orbea H, Diggelmann H. A Vβ4‐specific superantigen encoded by a new exogenous mouse mammary tumor virus European Journal of Immunology. 26: 1000-1006. PMID 8647159 DOI: 10.1002/Eji.1830260507  0.432
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