Year |
Citation |
Score |
2021 |
Shersher E, Lahiry M, Alvarez-Trotta A, Diluvio G, Robbins DJ, Shiekhattar R, Capobianco AJ. NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis. Cell Communication and Signaling : Ccs. 19: 96. PMID 34551776 DOI: 10.1186/s12964-021-00776-1 |
0.302 |
|
2021 |
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, ... ... Capobianco AJ, et al. The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling. Nature Communications. 12: 5263. PMID 34489457 DOI: 10.1038/s41467-021-25634-z |
0.424 |
|
2021 |
Alvarez-Trotta A, Guerrant W, Astudillo L, Lahiry M, Diluvio G, Shersher E, Kaneku H, Robbins DJ, Orton D, Capobianco AJ. Pharmacological disruption of the Notch1 transcriptional complex inhibits tumor growth by selectively targeting cancer stem cells. Cancer Research. PMID 33820800 DOI: 10.1158/0008-5472.CAN-20-3611 |
0.314 |
|
2018 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Mehrdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins D. MBRS-64. SURPRISING ROLE FOR WNT SIGNALING IN SONIC HEDGEHOG DRIVEN MEDULLOBLASTOMA Neuro-Oncology. 20: i142-i142. DOI: 10.1093/Neuonc/Noy059.508 |
0.361 |
|
2017 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Merhdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins DJ. PDTM-03. SURPRISING ROLE FOR WNT SIGNALING IN Trp53-MUTANT SHH MEDULLOBLASTOMA Neuro-Oncology. 19: vi190-vi190. DOI: 10.1093/Neuonc/Nox168.768 |
0.332 |
|
2016 |
Liu S, Lam Chan H, Bai F, Ma J, Scott A, Robbins DJ, Capobianco AJ, Zhu P, Pei XH. Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis. Oncotarget. PMID 27588406 DOI: 10.18632/Oncotarget.11746 |
0.41 |
|
2016 |
Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. PMID 27210761 DOI: 10.1016/J.Celrep.2016.04.070 |
0.371 |
|
2015 |
Li B, Giambelli C, Tang B, Winterbottom E, Long J, Jin K, Wang Z, Liang Fei D, Nguyen DM, Athar M, Wang B, Subbarayan PR, Wang L, Rai P, Ardalan B, ... Capobianco AJ, et al. Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context Dependent Manner. Molecular Pharmacology. PMID 26573582 DOI: 10.1124/Mol.115.100867 |
0.398 |
|
2015 |
Shao H, Kong R, Ferrari ML, Radtke F, Capobianco AJ, Liu ZJ. Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion. Plos One. 10: e0142815. PMID 26562315 DOI: 10.1371/journal.pone.0142815 |
0.31 |
|
2015 |
Long J, Tokhunts R, Old WM, Houel S, Rodgriguez-Blanco J, Singh S, Schilling N, Capobianco AJ, Ahn NG, Robbins DJ. Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties. Cell Reports. 10: 1280-7. PMID 25732819 DOI: 10.1016/J.Celrep.2015.01.058 |
0.305 |
|
2015 |
Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Epigenetic pathways and glioblastoma treatment: insights from signaling cascades. Journal of Cellular Biochemistry. 116: 351-63. PMID 25290986 DOI: 10.1002/Jcb.24990 |
0.334 |
|
2014 |
Pelullo M, Quaranta R, Talora C, Checquolo S, Cialfi S, Felli MP, te Kronnie G, Borga C, Besharat ZM, Palermo R, Di Marcotullio L, Capobianco AJ, Gulino A, Screpanti I, Bellavia D. Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL. Neoplasia (New York, N.Y.). 16: 1007-17. PMID 25499214 DOI: 10.1016/j.neo.2014.10.004 |
0.641 |
|
2014 |
Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. The Journal of Biological Chemistry. 289: 35494-502. PMID 25355313 DOI: 10.1074/Jbc.M114.595348 |
0.428 |
|
2014 |
Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, ... ... Capobianco AJ, et al. Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma. Cancer Research. 74: 6364-74. PMID 25164006 DOI: 10.1158/0008-5472.Can-14-2051 |
0.316 |
|
2014 |
Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Vasquez-Del Carpio R, Dahmane N, ... ... Capobianco AJ, et al. NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis. Cancer Research. 74: 4741-51. PMID 25038227 DOI: 10.1158/0008-5472.Can-14-1547 |
0.385 |
|
2014 |
Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, et al. Pyrvinium attenuates Hedgehog signaling downstream of smoothened. Cancer Research. 74: 4811-21. PMID 24994715 DOI: 10.1158/0008-5472.Can-14-0317 |
0.365 |
|
2013 |
Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, ... ... Capobianco AJ, et al. The hedgehog processing pathway is required for NSCLC growth and survival. Oncogene. 32: 2335-45. PMID 22733134 DOI: 10.1038/Onc.2012.243 |
0.391 |
|
2012 |
Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, ... ... Capobianco AJ, et al. Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Research. 72: 4449-58. PMID 22815529 DOI: 10.1158/0008-5472.Can-11-4123 |
0.401 |
|
2011 |
Ranganathan P, Vasquez-Del Carpio R, Kaplan FM, Wang H, Gupta A, VanWye JD, Capobianco AJ. Hierarchical phosphorylation within the ankyrin repeat domain defines a phosphoregulatory loop that regulates Notch transcriptional activity. The Journal of Biological Chemistry. 286: 28844-57. PMID 21685388 DOI: 10.1074/jbc.M111.243600 |
0.38 |
|
2011 |
Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63. PMID 21565978 DOI: 10.1158/0008-5472.Can-10-2313 |
0.381 |
|
2011 |
Ranganathan P, Weaver KL, Capobianco AJ. Notch signalling in solid tumours: a little bit of everything but not all the time. Nature Reviews. Cancer. 11: 338-51. PMID 21508972 DOI: 10.1038/Nrc3035 |
0.362 |
|
2011 |
Vasquez-Del Carpio R, Kaplan FM, Weaver KL, VanWye JD, Alves-Guerra MC, Robbins DJ, Capobianco AJ. Assembly of a Notch transcriptional activation complex requires multimerization. Molecular and Cellular Biology. 31: 1396-408. PMID 21245387 DOI: 10.1128/Mcb.00360-10 |
0.362 |
|
2011 |
Demarest RM, Dahmane N, Capobianco AJ. Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia. Blood. 117: 2901-9. PMID 21217079 DOI: 10.1182/blood-2010-05-286351 |
0.413 |
|
2010 |
Negorev DG, Vladimirova OV, Kossenkov AV, Nikonova EV, Demarest RM, Capobianco AJ, Showe MK, Rauscher FJ, Showe LC, Maul GG. Sp100 as a potent tumor suppressor: accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program. Cancer Research. 70: 9991-10001. PMID 21118961 DOI: 10.1158/0008-5472.Can-10-1483 |
0.391 |
|
2009 |
Pinnix CC, Lee JT, Liu ZJ, McDaid R, Balint K, Beverly LJ, Brafford PA, Xiao M, Himes B, Zabierowski SE, Yashiro-Ohtani Y, Nathanson KL, Bengston A, Pollock PM, Weeraratna AT, ... ... Capobianco AJ, et al. Active Notch1 confers a transformed phenotype to primary human melanocytes. Cancer Research. 69: 5312-20. PMID 19549918 DOI: 10.1158/0008-5472.Can-08-3767 |
0.355 |
|
2009 |
Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 113: 1689-98. PMID 19001083 DOI: 10.1182/Blood-2008-03-147967 |
0.576 |
|
2008 |
Demarest RM, Ratti F, Capobianco AJ. It's T-ALL about Notch. Oncogene. 27: 5082-91. PMID 18758476 DOI: 10.1038/onc.2008.222 |
0.477 |
|
2007 |
Alves-Guerra MC, Ronchini C, Capobianco AJ. Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival. Cancer Research. 67: 8690-8. PMID 17875709 DOI: 10.1158/0008-5472.CAN-07-1720 |
0.359 |
|
2007 |
Spaulding C, Reschly EJ, Zagort DE, Yashiro-Ohtani Y, Beverly LJ, Capobianco A, Pear WS, Kee BL. Notch1 co-opts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas. Blood. 110: 2650-8. PMID 17585052 DOI: 10.1182/Blood-2007-04-084202 |
0.631 |
|
2006 |
Sharma VM, Calvo JA, Draheim KM, Cunningham LA, Hermance N, Beverly L, Krishnamoorthy V, Bhasin M, Capobianco AJ, Kelliher MA. Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc. Molecular and Cellular Biology. 26: 8022-31. PMID 16954387 DOI: 10.1128/MCB.01091-06 |
0.552 |
|
2006 |
Beverly LJ, Ascano JM, Capobianco AJ. Expression of JAGGED1 in T-lymphocytes results in thymic involution by inducing apoptosis of thymic stromal epithelial cells. Genes and Immunity. 7: 476-86. PMID 16791277 DOI: 10.1038/sj.gene.6364318 |
0.519 |
|
2006 |
Liu ZJ, Xiao M, Balint K, Soma A, Pinnix CC, Capobianco AJ, Velazquez OC, Herlyn M. Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1009-11. PMID 16571776 DOI: 10.1096/Fj.05-4880Fje |
0.458 |
|
2006 |
Draheim KM, Sharma VM, Calvo JA, Cunningham LA, Hermance N, Krishnamoorthy V, Beverly L, Bhasin M, Capobianco A, Kelliher MA. Notch1 Provides a Proliferative Signal in Mouse T Cell Leukemia by Directly Targeting c-Myc. Blood. 108: 1434-1434. DOI: 10.1182/blood.v108.11.1434.1434 |
0.544 |
|
2005 |
Balint K, Xiao M, Pinnix CC, Soma A, Veres I, Juhasz I, Brown EJ, Capobianco AJ, Herlyn M, Liu ZJ. Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression. The Journal of Clinical Investigation. 115: 3166-76. PMID 16239965 DOI: 10.1172/Jci25001 |
0.465 |
|
2005 |
Zhang XY, DeSalle LM, Patel JH, Capobianco AJ, Yu D, Thomas-Tikhonenko A, McMahon SB. Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein. Proceedings of the National Academy of Sciences of the United States of America. 102: 13968-73. PMID 16172399 DOI: 10.1073/Pnas.0502330102 |
0.308 |
|
2005 |
Beverly LJ, Felsher DW, Capobianco AJ. Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression. Cancer Research. 65: 7159-68. PMID 16103066 DOI: 10.1158/0008-5472.Can-05-1664 |
0.379 |
|
2005 |
Carlson TR, Yan Y, Wu X, Lam MT, Tang GL, Beverly LJ, Messina LM, Capobianco AJ, Werb Z, Wang R. Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 9884-9. PMID 15994223 DOI: 10.1073/Pnas.0504391102 |
0.327 |
|
2004 |
Beverly LJ, Capobianco AJ. Targeting promiscuous signaling pathways in cancer: another Notch in the bedpost. Trends in Molecular Medicine. 10: 591-8. PMID 15567329 DOI: 10.1016/j.molmed.2004.10.001 |
0.357 |
|
2003 |
Beverly LJ, Capobianco AJ. Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis. Cancer Cell. 3: 551-64. PMID 12842084 DOI: 10.1016/S1535-6108(03)00137-5 |
0.45 |
|
2003 |
Ascano JM, Beverly LJ, Capobianco AJ. The C-terminal PDZ-ligand of JAGGED1 is essential for cellular transformation. The Journal of Biological Chemistry. 278: 8771-9. PMID 12496248 DOI: 10.1074/Jbc.M211427200 |
0.505 |
|
2002 |
Jeffries S, Robbins DJ, Capobianco AJ. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Molecular and Cellular Biology. 22: 3927-41. PMID 11997524 DOI: 10.1128/MCB.22.11.3927-3941.2002 |
0.488 |
|
2002 |
Chu J, Jeffries S, Norton JE, Capobianco AJ, Bresnick EH. Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain. The Journal of Biological Chemistry. 277: 7587-97. PMID 11739397 DOI: 10.1074/Jbc.M111044200 |
0.449 |
|
2001 |
Ronchini C, Capobianco AJ. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). Molecular and Cellular Biology. 21: 5925-34. PMID 11486031 DOI: 10.1128/Mcb.21.17.5925-5934.2001 |
0.434 |
|
2000 |
Ronchini C, Capobianco AJ. Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation. Oncogene. 19: 3914-24. PMID 10951584 DOI: 10.1038/Sj.Onc.1203719 |
0.468 |
|
2000 |
Jeffries S, Capobianco AJ. Neoplastic transformation by Notch requires nuclear localization. Molecular and Cellular Biology. 20: 3928-41. PMID 10805736 DOI: 10.1128/MCB.20.11.3928-3941.2000 |
0.46 |
|
2000 |
Lam LT, Ronchini C, Norton J, Capobianco AJ, Bresnick EH. Suppression of erythroid but not megakaryocytic differentiation of human K562 Erythroleukemic cells by Notch-1 Journal of Biological Chemistry. 275: 19676-19684. PMID 10783395 DOI: 10.1074/Jbc.M002866200 |
0.584 |
|
1997 |
Capobianco AJ, Zagouras P, Blaumueller CM, Artavanis-Tsakonas S, Bishop JM. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Molecular and Cellular Biology. 17: 6265-73. PMID 9343387 DOI: 10.1128/MCB.17.11.6265 |
0.517 |
|
1994 |
Bishop JM, Capobianco AJ, Doyle HJ, Finney RE, McMahon M, Robbins SM, Samuels ML, Vetter M. Proto-oncogenes and plasticity in cell signaling. Cold Spring Harbor Symposia On Quantitative Biology. 59: 165-71. PMID 7587066 DOI: 10.1101/Sqb.1994.059.01.020 |
0.516 |
|
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