Ying Ge - Publications

Affiliations: 
Chemistry University of Wisconsin, Madison, Madison, WI 
Area:
proteomics and metabolomics
Website:
http://www.chem.wisc.edu/users/yge

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chapman EA, Li BH, Krichel B, Chan HJ, Buck KM, Roberts DS, Ge Y. Native Top-Down Mass Spectrometry for Characterizing Sarcomeric Proteins Directly from Cardiac Tissue Lysate. Journal of the American Society For Mass Spectrometry. PMID 38422011 DOI: 10.1021/jasms.3c00430  0.413
2024 Rogers HT, Melby JA, Ehlers LE, Fischer MS, Larson EJ, Gao Z, Rossler KJ, Wang D, Alpert AJ, Ge Y. Small-Scale Serial Size Exclusion Chromatography (sSEC) for High Sensitivity Top-Down Proteomics of Large Proteoforms. Analytical Chemistry. PMID 38315630 DOI: 10.1021/acs.analchem.3c05733  0.374
2023 Brown KA, Morris RK, Eckhardt SJ, Ge Y, Gellman SH. Phosphorylation Sites of the Gastric Inhibitory Polypeptide Receptor (GIPR) Revealed by Trapped-Ion-Mobility Spectrometry Coupled to Time-of-Flight Mass Spectrometry (TIMS-TOF MS). Journal of the American Chemical Society. 145: 28030-28037. PMID 38091482 DOI: 10.1021/jacs.3c09078  0.32
2023 Pergande MR, Osterbauer KJ, Buck KM, Roberts DS, Wood NN, Balasubramanian P, Mann MW, Rossler KJ, Diffee GM, Colman RJ, Anderson RM, Ge Y. Mass Spectrometry-Based Multiomics Identifies Metabolic Signatures of Sarcopenia in Rhesus Monkey Skeletal Muscle. Journal of Proteome Research. PMID 37991985 DOI: 10.1021/acs.jproteome.3c00474  0.705
2023 Wancewicz B, Pergande MR, Zhu Y, Gao Z, Shi Z, Plouff K, Ge Y. Comprehensive Metabolomic Analysis of Human Heart Tissue Enabled by Parallel Metabolite Extraction and High-Resolution Mass Spectrometry. Biorxiv : the Preprint Server For Biology. PMID 37745334 DOI: 10.1101/2023.09.15.558013  0.728
2023 West KHJ, Ma SV, Pensinger DA, Tucholski T, Tiambeng TN, Eisenbraun EL, Yehuda A, Hayouka Z, Ge Y, Sauer JD, Blackwell HE. Characterization of an Autoinducing Peptide Signal Reveals Highly Efficacious Synthetic Inhibitors and Activators of Quorum Sensing and Biofilm Formation in . Biochemistry. PMID 37699554 DOI: 10.1021/acs.biochem.3c00373  0.701
2023 Lermyte F, Habeck T, Brown K, Des Soye B, Lantz C, Zhou M, Alam N, Hossain MA, Jung W, Keener J, Volny M, Wilson J, Ying Y, Agar J, Danis P, ... Ge Y, et al. Top-down mass spectrometry of native proteoforms and their complexes: A community study. Research Square. PMID 37674709 DOI: 10.21203/rs.3.rs-3228472/v1  0.645
2023 Rogers HT, Roberts DS, Larson EJ, Melby JA, Rossler KJ, Carr AV, Brown KA, Ge Y. Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics. Analytical Chemistry. PMID 37607050 DOI: 10.1021/acs.analchem.3c01618  0.436
2023 Pergande MR, Osterbauer KJ, Buck KM, Roberts DS, Wood NN, Balasubramanian P, Mann MW, Rossler K, Diffee GM, Colman RJ, Anderson RM, Ge Y. Mass spectrometry-based multi-omics identifies metabolic signatures of sarcopenia in rhesus monkey skeletal muscle. Biorxiv : the Preprint Server For Biology. PMID 37577600 DOI: 10.1101/2023.07.31.551315  0.707
2023 Bayne EF, Rossler KJ, Gregorich ZR, Aballo TJ, Roberts DS, Chapman EA, Guo W, Palecek SP, Ralphe JC, Kamp TJ, Ge Y. Top-down proteomics of myosin light chain isoforms define chamber-specific expression in the human heart. Journal of Molecular and Cellular Cardiology. 181: 89-97. PMID 37327991 DOI: 10.1016/j.yjmcc.2023.06.003  0.729
2023 Larson EJ, Pergande MR, Moss ME, Rossler KJ, Wenger RK, Krichel B, Josyer H, Melby JA, Roberts DS, Pike K, Shi Z, Chan HJ, Knight B, Rogers HT, Brown KA, ... ... Ge Y, et al. MASH Native: A Unified Solution for Native Top-Down Proteomics Data Processing. Bioinformatics (Oxford, England). PMID 37294807 DOI: 10.1093/bioinformatics/btad359  0.712
2023 Melby JA, Brown KA, Gregorich ZR, Roberts DS, Chapman EA, Ehlers LE, Gao Z, Larson EJ, Jin Y, Lopez JR, Hartung J, Zhu Y, McIlwain SJ, Wang D, Guo W, ... ... Ge Y, et al. High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. Proceedings of the National Academy of Sciences of the United States of America. 120: e2222081120. PMID 37126723 DOI: 10.1073/pnas.2222081120  0.791
2023 Rogers HT, Roberts DS, Larson EJ, Melby JA, Rossler KJ, Carr AV, Brown KA, Ge Y. Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics. Biorxiv : the Preprint Server For Biology. PMID 37090578 DOI: 10.1101/2023.04.12.536120  0.42
2023 Chapman EA, Aballo TJ, Melby JA, Zhou T, Price SJ, Rossler KJ, Lei I, Tang PC, Ge Y. Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-Down Proteomics. Journal of Proteome Research. PMID 36800490 DOI: 10.1021/acs.jproteome.2c00729  0.434
2023 Bayne EF, Rossler KJ, Gregorich ZR, Aballo TJ, Roberts DS, Chapman EA, Guo W, Ralphe JC, Kamp TJ, Ge Y. Top-down Proteomics of Myosin Light Chain Isoforms Define Chamber-Specific Expression in the Human Heart. Biorxiv : the Preprint Server For Biology. PMID 36747670 DOI: 10.1101/2023.01.26.525767  0.732
2023 Larson EJ, Pergande MR, Moss ME, Rossler KJ, Wenger RK, Krichel B, Josyer H, Melby JA, Roberts DS, Pike K, Shi Z, Chan HJ, Knight B, Rogers HT, Brown KA, ... ... Ge Y, et al. MASH Native: A Unified Solution for Native Top-Down Proteomics Data Processing. Biorxiv : the Preprint Server For Biology. PMID 36711733 DOI: 10.1101/2023.01.02.522513  0.691
2023 Brown KA, Gugger MK, Yu Z, Moreno D, Jin S, Ge Y. Nonionic, Cleavable Surfactant for Top-Down Proteomics. Analytical Chemistry. PMID 36608324 DOI: 10.1021/acs.analchem.2c03916  0.401
2022 Sun M, Jin Y, Zhang Y, Gregorich ZR, Ren J, Ge Y, Guo W. SR Protein Kinases Regulate the Splicing of Cardiomyopathy-Relevant Genes via Phosphorylation of the RSRSP Stretch in RBM20. Genes. 13. PMID 36140694 DOI: 10.3390/genes13091526  0.791
2022 Larson EJ, Gregorich ZR, Zhang Y, Li BH, Aballo TJ, Melby JA, Ge Y, Guo W. ablation is associated with changes in the expression of titin-interacting and metabolic proteins. Molecular Omics. PMID 35762193 DOI: 10.1039/d2mo00115b  0.709
2022 Tiambeng TN, Wu Z, Melby JA, Ge Y. Size Exclusion Chromatography Strategies and MASH Explorer for Large Proteoform Characterization. Methods in Molecular Biology (Clifton, N.J.). 2500: 15-30. PMID 35657584 DOI: 10.1007/978-1-0716-2325-1_3  0.326
2022 Buck KM, Roberts DS, Aballo TJ, Inman DR, Jin S, Ponik S, Brown KA, Ge Y. One-Pot Exosome Proteomics Enabled by a Photocleavable Surfactant. Analytical Chemistry. PMID 35543580 DOI: 10.1021/acs.analchem.2c01252  0.364
2022 Zhang Y, Wang C, Sun M, Jin Y, Braz CU, Khatib H, Hacker TA, Liss M, Gotthardt M, Granzier H, Ge Y, Guo W. RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22302. PMID 35394688 DOI: 10.1096/fj.202101811RR  0.693
2021 Smith LM, Agar JN, Chamot-Rooke J, Danis PO, Ge Y, Loo JA, Paša-Tolić L, Tsybin YO, Kelleher NL. The Human Proteoform Project: Defining the human proteome. Science Advances. 7: eabk0734. PMID 34767442 DOI: 10.1126/sciadv.abk0734  0.526
2021 Roberts DS, Mann M, Melby JA, Larson EJ, Zhu Y, Brasier AR, Jin S, Ge Y. Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry. Journal of the American Chemical Society. PMID 34328324 DOI: 10.1021/jacs.1c02713  0.302
2021 Larson EJ, Roberts DS, Melby JA, Buck KM, Zhu Y, Zhou S, Han L, Zhang Q, Ge Y. High-Throughput Multi-attribute Analysis of Antibody-Drug Conjugates Enabled by Trapped Ion Mobility Spectrometry and Top-Down Mass Spectrometry. Analytical Chemistry. PMID 34258999 DOI: 10.1021/acs.analchem.1c00150  0.313
2021 Aballo TJ, Roberts DS, Melby JA, Buck KM, Brown KA, Ge Y. Ultrafast and Reproducible Proteomics from Small Amounts of Heart Tissue Enabled by Azo and timsTOF Pro. Journal of Proteome Research. PMID 34236868 DOI: 10.1021/acs.jproteome.1c00446  0.429
2021 Melby JA, Roberts DS, Larson EJ, Brown KA, Bayne EF, Jin S, Ge Y. Novel Strategies to Address the Challenges in Top-Down Proteomics. Journal of the American Society For Mass Spectrometry. PMID 33983025 DOI: 10.1021/jasms.1c00099  0.368
2021 Kurgan KW, Chen B, Brown KA, Falco Cobra P, Ye X, Ge Y, Gellman SH. Stable Picodisc Assemblies from Saposin Proteins and Branched Detergents. Biochemistry. PMID 33755420 DOI: 10.1021/acs.biochem.0c00924  0.745
2021 Melby JA, de Lange WJ, Zhang J, Roberts DS, Mitchell SD, Tucholski T, Kim G, Kyrvasilis A, McIlwain SJ, Kamp TJ, Ralphe JC, Ge Y. Functionally Integrated Top-Down Proteomics for Standardized Assessment of Human Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues. Journal of Proteome Research. PMID 33395532 DOI: 10.1021/acs.jproteome.0c00830  0.74
2020 Zhou M, Lantz C, Brown KA, Ge Y, Paša-Tolić L, Loo JA, Lermyte F. Higher-order structural characterisation of native proteins and complexes by top-down mass spectrometry. Chemical Science. 11: 12918-12936. PMID 34094482 DOI: 10.1039/d0sc04392c  0.542
2020 Brown KA, Melby JA, Roberts DS, Ge Y. Top-down Proteomics: Challenges, Innovations, and Applications in Basic and Clinical Research. Expert Review of Proteomics. PMID 33232185 DOI: 10.1080/14789450.2020.1855982  0.361
2020 Knott SJ, Brown KA, Josyer H, Carr A, Inman D, Jin S, Friedl A, Ponik SM, Ge Y. Photocleavable Surfactant-Enabled Extracellular Matrix Proteomics. Analytical Chemistry. PMID 33232116 DOI: 10.1021/acs.analchem.0c03104  0.399
2020 Brown KA, Tucholski T, Alpert AJ, Eken C, Wesemann L, Kyrvasilis A, Jin S, Ge Y. Top-Down Proteomics of Endogenous Membrane Proteins Enabled by Cloud Point Enrichment and Multidimensional Liquid Chromatography-Mass Spectrometry. Analytical Chemistry. PMID 33231430 DOI: 10.1021/acs.analchem.0c02533  0.785
2020 Styles MJ, Early SA, Tucholski T, West KHJ, Ge Y, Blackwell HE. Chemical Control of Quorum Sensing in : Identification of Small Molecule Modulators of SdiA and Mechanistic Characterization of a Covalent Inhibitor. Acs Infectious Diseases. PMID 33124430 DOI: 10.1021/acsinfecdis.0c00654  0.707
2020 Larson EJ, Zhu Y, Wu Z, Chen B, Zhang Z, Zhou S, Han L, Zhang Q, Ge Y. Rapid Analysis of Reduced Antibody Drug Conjugate by Online LC-MS/MS with Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Analytical Chemistry. PMID 33108180 DOI: 10.1021/acs.analchem.0c03152  0.762
2020 Zhu Y, Wancewicz B, Schaid M, Tiambeng TN, Wenger K, Jin Y, Heyman H, Thompson CJ, Barsch A, Cox ED, Davis DB, Brasier AR, Kimple M, Ge Y. Ultrahigh-Resolution Mass Spectrometry-Based Platform for Plasma Metabolomics Applied to Type 2 Diabetes Research. Journal of Proteome Research. PMID 33054244 DOI: 10.1021/acs.jproteome.0c00510  0.714
2020 Tucholski T, Cai W, Gregorich ZR, Bayne EF, Mitchell SD, McIlwain SJ, de Lange WJ, Wrobbel M, Karp H, Hite Z, Vikhorev PG, Marston SB, Lal S, Li A, Dos Remedios C, ... ... Ge Y, et al. Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics. Proceedings of the National Academy of Sciences of the United States of America. PMID 32968017 DOI: 10.1073/pnas.2006764117  0.804
2020 Tucholski T, Ge Y. Fourier-transform ion cyclotron resonance mass spectrometry for characterizing proteoforms. Mass Spectrometry Reviews. PMID 32894796 DOI: 10.1002/Mas.21653  0.801
2020 Kellie JF, Tran JC, Jian W, Jones BR, Mehl JT, Ge Y, Henion J, Bateman KP. Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics and Biotransformation in Pre-Clinical and Clinical Studies: An Industry Perspective. Journal of the American Society For Mass Spectrometry. PMID 32869982 DOI: 10.1021/Jasms.0C00270  0.427
2020 Srzentić K, Fornelli L, Tsybin YO, Loo JA, Seckler H, Agar JN, Anderson LC, Bai DL, Beck A, Brodbelt JS, van der Burgt YEM, Chamot-Rooke J, Chatterjee S, Chen Y, Clarke DJ, ... ... Ge Y, et al. Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 32812765 DOI: 10.1021/Jasms.0C00036  0.682
2020 Wu Z, Roberts DS, Melby JA, Wenger K, Wetzel M, Gu Y, Ramanathan SG, Bayne EF, Liu X, Sun R, Ong IM, McIlwain SJ, Ge Y. MASH Explorer: A Universal Software Environment for Top-Down Proteomics. Journal of Proteome Research. PMID 32786689 DOI: 10.1021/Acs.Jproteome.0C00469  0.399
2020 Tiambeng TN, Roberts DS, Brown KA, Zhu Y, Chen B, Wu Z, Mitchell SD, Guardado-Alvarez TM, Jin S, Ge Y. Nanoproteomics enables proteoform-resolved analysis of low-abundance proteins in human serum. Nature Communications. 11: 3903. PMID 32764543 DOI: 10.1038/S41467-020-17643-1  0.81
2020 Xu B, Li M, Wang Y, Zhao M, Morotti S, Shi Q, Wang Q, Barbagallo F, Teoh JP, Raghavender Reddy G, Bayne EF, Liu Y, Shen A, Puglisi JL, Ge Y, et al. GRK5 Controls SAP97-Dependent Cardiotoxic β1 Adrenergic Receptor-CaMKII Signaling in Heart Failureβ. Circulation Research. PMID 32507058 DOI: 10.1161/Circresaha.119.316319  0.317
2020 McIlwain SJ, Wu Z, Wetzel M, Belongia D, Jin Y, Wenger K, Ong IM, Ge Y. Enhancing Top-Down Proteomics Data Analysis by Combining Deconvolution Results through a Machine Learning Strategy. Journal of the American Society For Mass Spectrometry. PMID 32223200 DOI: 10.1021/Jasms.0C00035  0.71
2020 Brown K, Tucholski T, Eken C, Knott S, Zhu Y, Jin S, Ge Y. High-throughput Proteomics Enabled by a Photocleavable Surfactant. Angewandte Chemie (International Ed. in English). PMID 32097521 DOI: 10.1002/Anie.201915374  0.814
2020 Zhang F, Wyche TP, Zhu Y, Braun DR, Yan JX, Chanana S, Ge Y, Guzei IA, Chevrette MG, Currie CR, Thomas MG, Rajski SR, Bugni TS. MS-Derived Isotopic Fine Structure Reveals Forazoline A as a Thioketone-Containing Marine-Derived Natural Product. Organic Letters. PMID 32017574 DOI: 10.1021/Acs.Orglett.9B04535  0.306
2019 Lin Z, Wei L, Cai W, Zhu Y, Tucholski T, Mitchell SD, Guo W, Ford SP, Diffee GM, Ge Y. Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of the Sarcomeric Subproteome. Molecular & Cellular Proteomics : McP. 18: 594-605. PMID 33431132 DOI: 10.1074/mcp.TIR118.001086  0.837
2019 Wu Z, Jin Y, Chen B, Gugger MK, Wilkinson-Johnson CL, Tiambeng TN, Jin S, Ge Y. Comprehensive Characterization of the Recombinant Catalytic Subunit of cAMP-Dependent Protein Kinase by Top-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. 30: 2561-2570. PMID 31944732 DOI: 10.1021/jasms.8b06294  0.317
2019 Jin Y, Diffee GM, Colman RJ, Anderson RM, Ge Y. Top-down Mass Spectrometry of Sarcomeric Protein Post-translational Modifications from Non-human Primate Skeletal Muscle. Journal of the American Society For Mass Spectrometry. 30: 2460-2469. PMID 31944707 DOI: 10.1021/jasms.8b06267  0.364
2019 Wu Z, Jin Y, Chen B, Gugger MK, Wilkinson-Johnson CL, Tiambeng TN, Jin S, Ge Y. Comprehensive Characterization of the Recombinant Catalytic Subunit of cAMP-Dependent Protein Kinase by Top-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 31792770 DOI: 10.1007/S13361-019-02341-0  0.815
2019 Melby JA, Jin Y, Lin Z, Tucholski T, Wu Z, Gregorich ZR, Diffee GM, Ge Y. Top-Down Proteomics Reveals Myofilament Proteoform Heterogeneity among Various Rat Skeletal Muscle Tissues. Journal of Proteome Research. PMID 31647247 DOI: 10.1021/Acs.Jproteome.9B00623  0.812
2019 Tiambeng TN, Tucholski T, Wu Z, Zhu Y, Mitchell SD, Roberts DS, Jin Y, Ge Y. Analysis of cardiac troponin proteoforms by top-down mass spectrometry. Methods in Enzymology. 626: 347-374. PMID 31606082 DOI: 10.1016/Bs.Mie.2019.07.029  0.839
2019 Cai W, Zhang J, De Lange WJ, Gregorich ZR, Karp H, Farrell ET, Mitchell ST, Tucholski T, Lin Z, Biermann M, McIlwain S, Ralphe JC, Kamp TJ, Ge Y. Unbiased Proteomics Method to Assess the Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Research. PMID 31573406 DOI: 10.1161/Circresaha.119.315305  0.794
2019 Smith LM, Thomas PM, Shortreed MR, Schaffer LV, Fellers RT, LeDuc RD, Tucholski T, Ge Y, Agar JN, Anderson LC, Chamot-Rooke J, Gault J, Loo JA, Paša-Tolić L, Robinson CV, et al. A five-level classification system for proteoform identifications. Nature Methods. PMID 31451767 DOI: 10.1038/S41592-019-0573-X  0.812
2019 Chen B, Lin Z, Zhu Y, Jin Y, Larson E, Xu Q, Fu C, Zhang Z, Zhang Q, Pritts W, Ge Y. Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation. Analytical Chemistry. PMID 31442030 DOI: 10.1021/Acs.Analchem.9B02194  0.792
2019 Schaffer LV, Tucholski T, Shortreed MR, Ge Y, Smith LM. Intact-Mass Analysis Facilitates the Identification of Large Human Heart Proteoforms. Analytical Chemistry. PMID 31393705 DOI: 10.1021/Acs.Analchem.9B02343  0.809
2019 Roberts DS, Chen B, Tiambeng TN, Wu Z, Ge Y, Jin S. Reproducible Large-Scale Synthesis of Surface Silanized Nanoparticles as an Enabling Nanoproteomics Platform: Enrichment of the Human Heart Phosphoproteome. Nano Research. 12: 1473-1481. PMID 31341559 DOI: 10.1007/S12274-019-2418-4  0.772
2019 Donnelly DP, Rawlins CM, DeHart CJ, Fornelli L, Schachner LF, Lin Z, Lippens JL, Aluri KC, Sarin R, Chen B, Lantz C, Jung W, Johnson KR, Koller A, Wolff JJ, ... ... Ge Y, et al. Best practices and benchmarks for intact protein analysis for top-down mass spectrometry. Nature Methods. 16: 587-594. PMID 31249407 DOI: 10.1038/S41592-019-0457-0  0.828
2019 Biermann M, Cai W, Lang D, Hermsen J, Profio L, Zhou Y, Czirok A, Isai DG, Napiwocki BN, Rodriguez AM, Brown ME, Woon MT, Shao A, Han T, Park D, ... ... Ge Y, et al. Epigenetic Priming of Human Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation. Stem Cells (Dayton, Ohio). PMID 31087611 DOI: 10.1002/Stem.3021  0.693
2019 Schaffer LV, Millikin RJ, Miller RM, Anderson LC, Fellers RT, Ge Y, Kelleher NL, LeDuc RD, Liu X, Payne SH, Sun L, Thomas PM, Tucholski T, Wang Z, Wu S, et al. Identification and Quantification of Proteoforms by Mass Spectrometry. Proteomics. e1800361. PMID 31050378 DOI: 10.1002/Pmic.201800361  0.809
2019 Brown KA, Chen B, Guardado-Alvarez TM, Lin Z, Hwang L, Ayaz-Guner S, Jin S, Ge Y. A photocleavable surfactant for top-down proteomics. Nature Methods. PMID 30988469 DOI: 10.1038/S41592-019-0391-1  0.791
2019 Jin Y, Diffee GM, Colman RJ, Anderson RM, Ge Y. Top-down Mass Spectrometry of Sarcomeric Protein Post-translational Modifications from Non-human Primate Skeletal Muscle. Journal of the American Society For Mass Spectrometry. PMID 30834509 DOI: 10.1007/S13361-019-02139-0  0.759
2019 Tucholski T, Knott S, Chen B, Pistono P, Lin Z, Ge Y. A Top-Down Proteomics Platform Coupling Serial Size Exclusion Chromatography and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Analytical Chemistry. PMID 30758949 DOI: 10.1021/Acs.Analchem.8B04082  0.838
2019 Liang Y, Jin Y, Wu Z, Tucholski T, Brown KA, Zhang L, Zhang Y, Ge Y. Bridged Hybrid Monolithic Column Coupled to High-Resolution Mass Spectrometry for Top-down Proteomics. Analytical Chemistry. PMID 30668094 DOI: 10.1021/Acs.Analchem.8B05817  0.836
2019 Gregorich ZR, Patel JR, Cai W, Lin Z, Heurer R, Fitzsimons DP, Moss RL, Ge Y. Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium. The Journal of General Physiology. PMID 30642915 DOI: 10.1085/Jgp.201812214  0.809
2019 Sun M, Jin Y, Zhu C, Rexiati M, Cai H, Liss M, Gotthardt M, Ge Y, Guo W. Abstract 891: Phosphorylation of RNA Binding Motif 20 is a Novel Target to Reduce Myocardial Stiffness in Diastolic Dysfunction Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.891  0.669
2019 Schaffer LV, Millikin RJ, Miller RM, Anderson LC, Fellers RT, Ge Y, Kelleher NL, LeDuc RD, Liu X, Payne SH, Sun L, Thomas PM, Tucholski T, Wang Z, Wu S, et al. Back Cover: Identification and Quantification of Proteoforms by Mass Spectrometry Proteomics. 19: 1970085. DOI: 10.1002/Pmic.201970085  0.799
2018 Lin Z, Wei L, Cai W, Zhu Y, Tucholski T, Mitchell SD, Guo W, Ford SP, Diffee GM, Ge Y. Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of Sarcomeric Subproteome. Molecular & Cellular Proteomics : McP. PMID 30591534 DOI: 10.1074/Mcp.Tir118.001086  0.836
2018 Chen B, Brown KA, Lin Z, Ge Y. Correction to Top-Down Proteomics: Ready for Prime Time? Analytical Chemistry. PMID 30522269 DOI: 10.1021/Acs.Analchem.8B05506  0.725
2018 Jin Y, Lin Z, Xu Q, Fu C, Zhang Z, Zhang Q, Pritts WA, Ge Y. Comprehensive characterization of monoclonal antibody by Fourier transform ion cyclotron resonance mass spectrometry. Mabs. PMID 30230956 DOI: 10.1080/19420862.2018.1525253  0.747
2018 Cai W, Hite ZL, Lyu B, Wu Z, Lin Z, Gregorich ZR, Messer AE, McIlwain S, Marston SB, Kohmoto T, Ge Y. Temperature-sensitive sarcomeric protein post-translational modifications revealed by top-down proteomics. Journal of Molecular and Cellular Cardiology. PMID 30048711 DOI: 10.1016/J.Yjmcc.2018.07.247  0.806
2018 Chen B, Lin Z, Alpert AJ, Fu C, Zhang Q, Pritts WA, Ge Y. Online Hydrophobic Interaction Chromatography-Mass Spectrometry for the Analysis of Intact Monoclonal Antibodies. Analytical Chemistry. PMID 29846060 DOI: 10.1021/Acs.Analchem.8B01865  0.792
2018 Martin-Garrido A, Biesiadecki BJ, Salhi HE, Shaifta Y, Dos Remedios CG, Ayuz-Guner S, Cai W, Ge Y, Avkiran M, Kentish JC. Monophosphorylation of cardiac troponin-I at Ser23/24 is sufficient to regulate cardiac myofibrillar Ca sensitivity and calpain-induced proteolysis. The Journal of Biological Chemistry. PMID 29669813 DOI: 10.1074/Jbc.Ra117.001292  0.716
2018 Lin Z, Guo F, Gregorich ZR, Sun R, Zhang H, Hu Y, Shanmuganayagam D, Ge Y. Comprehensive Characterization of Swine Cardiac Troponin T Proteoforms by Top-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 29633223 DOI: 10.1007/S13361-018-1925-Y  0.785
2018 Wu Z, Tiambeng TN, Cai W, Chen B, Lin Z, Gregorich ZR, Ge Y. What is the Impact of Phosphorylation on the Mass Spectrometry Quantification of Intact Phosphoproteins? Analytical Chemistry. PMID 29565561 DOI: 10.1021/Acs.Analchem.7B05246  0.827
2018 Smelter DF, De Lange WJ, Cai W, Ge Y, Ralphe JC. The HCM-linked W792R mutation in cardiac myosin binding protein-C reduces C6 FnIII domain stability. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29451820 DOI: 10.1152/Ajpheart.00686.2017  0.714
2018 Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/Nchembio.2576  0.792
2018 Chen Z, Song J, Chen L, Zhu C, Cai H, Sun M, Stern A, Mozdziak P, Ge Y, Means WJ, Guo W. Characterization of TTN Novex Splicing Variants across Species and the Role of RBM20 in Novex-Specific Exon Splicing. Genes. 9. PMID 29438341 DOI: 10.3390/Genes9020086  0.338
2018 LeDuc RD, Schwämmle V, Shortreed MR, Cesnik AJ, Solntsev SK, Shaw JB, Martin MJ, Vizcaíno JA, Alpi E, Danis P, Kelleher NL, Smith LM, Ge Y, Agar JN, Chamot-Rooke J, et al. ProForma: a Standard Proteoform Notation. Journal of Proteome Research. PMID 29397739 DOI: 10.1021/Acs.Jproteome.7B00851  0.603
2018 Kentish JC, Martin-Garrido A, Biesiadecki BJ, Salhi HE, Shaifta Y, Dos Remedios C, Ayaz-Guner S, Cai W, Ge Y, Avkiran M. P457Monophosphorylation of cardiac troponin-I at Ser23/24 regulates cardiac myofibrillar Ca2+ sensitivity and modulates calpain-induced proteolysis Cardiovascular Research. 114: S110-S110. DOI: 10.1093/Cvr/Cvy060.316  0.688
2017 Gao L, Gregorich ZR, Zhu W, Mattapally S, Oduk Y, Lou X, Kannappan R, Borovjagin AV, Walcott GP, Pollard AE, Fast VG, Hu X, Lloyd SG, Ge Y, Zhang J. Large Cardiac-Muscle Patches Engineered from Human Induced-Pluripotent Stem-Cell-Derived Cardiac Cells Improve Recovery from Myocardial Infarction in Swine. Circulation. PMID 29233823 DOI: 10.1161/Circulationaha.117.030785  0.709
2017 Chen B, Brown KA, Lin Z, Ge Y. Top-down Proteomics: Ready for Prime Time? Analytical Chemistry. PMID 29161012 DOI: 10.1021/Acs.Analchem.7B04747  0.785
2017 Hu CW, Worth M, Fan D, Li B, Li H, Lu L, Zhong X, Lin Z, Wei L, Ge Y, Li L, Jiang J. Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nature Chemical Biology. PMID 29058723 DOI: 10.1038/Nchembio.2494  0.338
2017 Wei L, Gregorich ZR, Lin Z, Cai W, Jin Y, McKiernan SH, McIlwain S, Aiken JM, Moss RL, Diffee GM, Ge Y. Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications in Skeletal Muscles Identified by Top-down Proteomics. Molecular & Cellular Proteomics : McP. PMID 29046390 DOI: 10.1074/Mcp.Ra117.000124  0.795
2017 Wu CG, Chen H, Guo F, Yadav VK, Mcilwain SJ, Rowse M, Choudhary A, Lin Z, Li Y, Gu T, Zheng A, Xu Q, Lee W, Resch E, Johnson B, ... ... Ge Y, et al. PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis. Cell Discovery. 3: 17027. PMID 28884018 DOI: 10.1038/Celldisc.2017.27  0.317
2017 Crowe SO, Rana ASJB, Deol KK, Ge Y, Strieter ER. Correction to Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains in Cellulo. Analytical Chemistry. PMID 28792741 DOI: 10.1021/Acs.Analchem.7B02855  0.329
2017 Rana ASJB, Ge Y, Strieter ER. Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry (UbiChEM-MS) Reveals Cell-Cycle Dependent Formation of Lys11/Lys48 Branched Ubiquitin Chains. Journal of Proteome Research. PMID 28737031 DOI: 10.1021/Acs.Jproteome.7B00381  0.357
2017 Chen B, Guo X, Tucholski T, Lin Z, McIlwain S, Ge Y. The Impact of Phosphorylation on Electron Capture Dissociation of Proteins: A Top-Down Perspective. Journal of the American Society For Mass Spectrometry. PMID 28685494 DOI: 10.1007/S13361-017-1710-3  0.8
2017 Chen B, Hwang L, Ochowicz W, Lin Z, Guardado-Alvarez TM, Cai W, Xiu L, Dani K, Colah C, Jin S, Ge Y. Coupling functionalized cobalt ferrite nanoparticle enrichment with online LC/MS/MS for top-down phosphoproteomics. Chemical Science. 8: 4306-4311. PMID 28660060 DOI: 10.1039/C6Sc05435H  0.831
2017 Gregorich ZR, Cai W, Lin Z, Chen AJ, Peng Y, Kohmoto T, Ge Y. Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. Journal of Molecular and Cellular Cardiology. PMID 28427997 DOI: 10.1016/J.Yjmcc.2017.04.002  0.816
2017 Cai W, Tucholski T, Chen B, Alpert AJ, McIlwain S, Kohmoto T, Jin S, Ge Y. Top-down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy. Analytical Chemistry. PMID 28406609 DOI: 10.1021/Acs.Analchem.7B00380  0.83
2017 Jin Y, Wei L, Cai W, Lin Z, Wu Z, Peng Y, Kohmoto T, Moss RL, Ge Y. Complete Characterization of Cardiac Myosin Heavy Chain (223 kDa) Enabled by Size-Exclusion Chromatography and Middle-down Mass Spectrometry. Analytical Chemistry. PMID 28366003 DOI: 10.1021/Acs.Analchem.7B00113  0.833
2017 Yang L, Gregorich ZR, Cai W, Zhang P, Young B, Gu Y, Zhang J, Ge Y. Quantitative Proteomics and Immunohistochemistry Reveal Insights into Cellular and Molecular Processes in the Infarct Border Zone One Month after Myocardial Infarction. Journal of Proteome Research. PMID 28347137 DOI: 10.1021/Acs.Jproteome.7B00107  0.797
2017 Crowe SO, Rana AS, Deol KK, Ge Y, Strieter ER. Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry (UbiCHEM-MS) Enables Characterization of Branched Ubiquitin Chains In Cellulo. Analytical Chemistry. PMID 28291339 DOI: 10.1021/Acs.Analchem.6B03675  0.359
2017 Cai W, Zhang J, de Lange WJ, Gregorich Z, Carter Ralphe J, Kamp T, Ge Y. Top-down proteomics for assessing the maturation of stem cell-derived cardiomyocytes Journal of Molecular and Cellular Cardiology. 112: 165-166. DOI: 10.1016/J.Yjmcc.2017.07.104  0.766
2017 Gregorich Z, Patel J, Cai W, Heurer R, Lin Z, Moss R, Ge Y. Deletion of the Z-disc Protein Enigma Homolog Depresses Cross-bridge Cycling Kinetics in Mouse Myocardium Journal of Molecular and Cellular Cardiology. 112: 142. DOI: 10.1016/J.Yjmcc.2017.07.037  0.778
2016 Cai W, Tucholski TM, Gregorich ZR, Ge Y. Top-down Proteomics for Comprehensive Analysis of Protein Isoforms and Modifications: Technology Advancements and Applications to Heart Diseases. Expert Review of Proteomics. PMID 27448560 DOI: 10.1080/14789450.2016.1209414  0.777
2016 Gregorich ZR, Peng Y, Cai W, Jin Y, Wei L, Chen AJ, McKiernan SH, Aiken JM, Moss RL, Diffee GM, Ge Y. Top-down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light Chain Phosphorylation that Contributes to Sarcopenic Muscle Dysfunction. Journal of Proteome Research. PMID 27362462 DOI: 10.1021/Acs.Jproteome.6B00244  0.79
2016 Crowe SO, Pham GH, Guenette RG, Ziegler JC, Deol KK, Ge Y, Strieter E. Subunit-Specific Labeling of Ubiquitin Chains Using Sortase: Insights into the Selectivity of Deubiquitinases. Chembiochem : a European Journal of Chemical Biology. PMID 27256865 DOI: 10.1002/Cbic.201600276  0.305
2016 Jin Y, Peng Y, Lin Z, Chen YC, Wei L, Hacker TA, Larsson L, Ge Y. Comprehensive analysis of tropomyosin isoforms in skeletal muscles by top-down proteomics. Journal of Muscle Research and Cell Motility. PMID 27090236 DOI: 10.1007/S10974-016-9443-7  0.712
2016 Chen B, Peng Y, Valeja SG, Xiu L, Alpert AJ, Ge Y. Online Hydrophobic Interaction Chromatography-Mass spectrometry for Top-down Proteomics. Analytical Chemistry. PMID 26729044 DOI: 10.1021/Acs.Analchem.5B04285  0.807
2015 Ge Y, Ning Z, Wang Y, Zheng Y, Zhang C, Figeys D. Quantitative proteomic analysis of Dunaliella salina upon acute arsenate exposure. Chemosphere. 145: 112-118. PMID 26688246 DOI: 10.1016/J.Chemosphere.2015.11.049  0.302
2015 Cai W, Guner H, Gregorich ZR, Chen AJ, Ayaz-Guner S, Peng Y, Valeja SG, Liu X, Ge Y. MASH Suite Pro: A Comprehensive Software Tool for Top-down Proteomics. Molecular & Cellular Proteomics : McP. PMID 26598644 DOI: 10.1074/Mcp.O115.054387  0.826
2015 Yu D, Peng Y, Ayaz-Guner S, Gregorich ZR, Ge Y. Comprehensive Characterization of AMP-Activated Protein Kinase Catalytic Domain by Top-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 26489410 DOI: 10.1007/S13361-015-1286-8  0.727
2015 Gregorich ZR, Peng Y, Lane NM, Wolff JJ, Wang S, Guo W, Guner H, Doop J, Hacker TA, Ge Y. Comprehensive assessment of chamber-specific and transmural heterogeneity in myofilament protein phosphorylation by top-down mass spectrometry. Journal of Molecular and Cellular Cardiology. 87: 102-112. PMID 26268593 DOI: 10.1016/J.Yjmcc.2015.08.007  0.761
2015 Chen YC, Ayaz-Guner S, Peng Y, Lane NM, Locher MR, Kohmoto T, Larsson L, Moss RL, Ge Y. Effective Top-Down LC/MS+ Method for Assessing Actin Isoforms as a Potential Cardiac Disease Marker. Analytical Chemistry. 87: 8399-406. PMID 26189812 DOI: 10.1021/Acs.Analchem.5B01745  0.405
2015 Chang YH, Ye L, Cai W, Lee Y, Guner H, Lee Y, Kamp TJ, Zhang J, Ge Y. Quantitative Proteomics Reveals Differential Regulation of Protein Expression in Recipient Myocardium after Trilineage Cardiovascular Cell Transplantation. Proteomics. PMID 26033914 DOI: 10.1002/Pmic.201500131  0.737
2015 Valeja SG, Xiu L, Gregorich ZR, Guner H, Jin S, Ge Y. Three dimensional liquid chromatography coupling ion exchange chromatography/hydrophobic interaction chromatography/reverse phase chromatography for effective protein separation in top-down proteomics. Analytical Chemistry. 87: 5363-71. PMID 25867201 DOI: 10.1021/Acs.Analchem.5B00657  0.768
2015 Hwang L, Ayaz-Guner S, Gregorich ZR, Cai W, Valeja SG, Jin S, Ge Y. Specific enrichment of phosphoproteins using functionalized multivalent nanoparticles. Journal of the American Chemical Society. 137: 2432-5. PMID 25655481 DOI: 10.1021/Ja511833Y  0.799
2015 Chen YC, Sumandea MP, Larsson L, Moss RL, Ge Y. Dissecting human skeletal muscle troponin proteoforms by top-down mass spectrometry. Journal of Muscle Research and Cell Motility. 36: 169-81. PMID 25613324 DOI: 10.1007/S10974-015-9404-6  0.412
2015 Chang YH, Gregorich ZR, Chen AJ, Hwang L, Guner H, Yu D, Zhang J, Ge Y. New mass-spectrometry-compatible degradable surfactant for tissue proteomics. Journal of Proteome Research. 14: 1587-99. PMID 25589168 DOI: 10.1021/Pr5012679  0.776
2014 Valkevich EM, Sanchez NA, Ge Y, Strieter ER. Middle-down mass spectrometry enables characterization of branched ubiquitin chains. Biochemistry. 53: 4979-89. PMID 25023374 DOI: 10.1021/Bi5006305  0.368
2014 Peng Y, Gregorich ZR, Valeja SG, Zhang H, Cai W, Chen YC, Guner H, Chen AJ, Schwahn DJ, Hacker TA, Liu X, Ge Y. Top-down proteomics reveals concerted reductions in myofilament and Z-disc protein phosphorylation after acute myocardial infarction. Molecular & Cellular Proteomics : McP. 13: 2752-64. PMID 24969035 DOI: 10.1074/Mcp.M114.040675  0.827
2014 Xiu L, Valeja SG, Alpert AJ, Jin S, Ge Y. Effective protein separation by coupling hydrophobic interaction and reverse phase chromatography for top-down proteomics. Analytical Chemistry. 86: 7899-906. PMID 24968279 DOI: 10.1021/Ac501836K  0.493
2014 Peng Y, Ayaz-Guner S, Yu D, Ge Y. Top-down mass spectrometry of cardiac myofilament proteins in health and disease. Proteomics. Clinical Applications. 8: 554-68. PMID 24945106 DOI: 10.1002/Prca.201400043  0.512
2014 Gregorich ZR, Ge Y. Top-down proteomics in health and disease: challenges and opportunities. Proteomics. 14: 1195-210. PMID 24723472 DOI: 10.1002/Pmic.201300432  0.751
2014 Gregorich ZR, Chang YH, Ge Y. Proteomics in heart failure: top-down or bottom-up? Pflã¼Gers Archiv : European Journal of Physiology. 466: 1199-209. PMID 24619480 DOI: 10.1007/S00424-014-1471-9  0.777
2014 Witayavanitkul N, Ait Mou Y, Kuster DW, Khairallah RJ, Sarkey J, Govindan S, Chen X, Ge Y, Rajan S, Wieczorek DF, Irving T, Westfall MV, de Tombe PP, Sadayappan S. Myocardial infarction-induced N-terminal fragment of cardiac myosin-binding protein C (cMyBP-C) impairs myofilament function in human myocardium. The Journal of Biological Chemistry. 289: 8818-27. PMID 24509847 DOI: 10.1074/Jbc.M113.541128  0.352
2014 Chen S, Zhu P, Guo HM, Solis RS, Wang Y, Ma Y, Wang J, Gao J, Chen JM, Ge Y, Zhuang J, Li J. Alpha1 catalytic subunit of AMPK modulates contractile function of cardiomyocytes through phosphorylation of troponin I. Life Sciences. 98: 75-82. PMID 24447627 DOI: 10.1016/J.Lfs.2014.01.006  0.336
2014 Guner H, Close PL, Cai W, Zhang H, Peng Y, Gregorich ZR, Ge Y. MASH Suite: a user-friendly and versatile software interface for high-resolution mass spectrometry data interpretation and visualization. Journal of the American Society For Mass Spectrometry. 25: 464-70. PMID 24385400 DOI: 10.1007/S13361-013-0789-4  0.804
2014 Witayavanitkul N, Sarkey J, Aitmou Y, Kuster DW, Khairallah RJ, Govindan S, Chen X, Ge Y, Rajan S, Wieczorek DF, Irving T, de Tombe PP, Sadayappan S. Myocardial Infarction-Induced N-Terminal Fragment of Cmybp-C Impairs Myofilament Function in Human Left Ventricular Myofibrils Biophysical Journal. 106: 347a. DOI: 10.1016/J.Bpj.2013.11.1977  0.368
2013 Zhao DS, Gregorich ZR, Ge Y. High throughput screening of disulfide-containing proteins in a complex mixture. Proteomics. 13: 3256-60. PMID 24030959 DOI: 10.1002/Pmic.201300242  0.776
2013 Peng Y, Yu D, Gregorich Z, Chen X, Beyer AM, Gutterman DD, Ge Y. In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry. Journal of Muscle Research and Cell Motility. 34: 199-210. PMID 23881156 DOI: 10.1007/S10974-013-9352-Y  0.755
2013 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ, Cui L. Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development. Molecular Microbiology. 89: 660-75. PMID 23796209 DOI: 10.1111/Mmi.12303  0.391
2013 Chen X, Ge Y. Ultrahigh pressure fast size exclusion chromatography for top-down proteomics. Proteomics. 13: 2563-6. PMID 23794208 DOI: 10.1002/Pmic.201200594  0.497
2013 Peng Y, Chen X, Zhang H, Xu Q, Hacker TA, Ge Y. Top-down targeted proteomics for deep sequencing of tropomyosin isoforms. Journal of Proteome Research. 12: 187-98. PMID 23256820 DOI: 10.1021/Pr301054N  0.431
2013 Guy MJ, Chen YC, Clinton L, Zhang H, Zhang J, Dong X, Xu Q, Ayaz-Guner S, Ge Y. The impact of antibody selection on the detection of cardiac troponin I. Clinica Chimica Acta; International Journal of Clinical Chemistry. 420: 82-8. PMID 23107929 DOI: 10.1016/J.Cca.2012.10.034  0.31
2012 Yang C, Park AC, Davis NA, Russell JD, Kim B, Brand DD, Lawrence MJ, Ge Y, Westphall MS, Coon JJ, Greenspan DS. Comprehensive mass spectrometric mapping of the hydroxylated amino acid residues of the α1(V) collagen chain. The Journal of Biological Chemistry. 287: 40598-610. PMID 23060441 DOI: 10.1074/Jbc.M112.406850  0.303
2012 Jia C, Hui L, Cao W, Lietz CB, Jiang X, Chen R, Catherman AD, Thomas PM, Ge Y, Kelleher NL, Li L. High-definition de novo sequencing of crustacean hyperglycemic hormone (CHH)-family neuropeptides. Molecular & Cellular Proteomics : McP. 11: 1951-64. PMID 23028060 DOI: 10.1074/Mcp.M112.020537  0.546
2012 Valkevich EM, Guenette RG, Sanchez NA, Chen YC, Ge Y, Strieter ER. Forging isopeptide bonds using thiol-ene chemistry: site-specific coupling of ubiquitin molecules for studying the activity of isopeptidases. Journal of the American Chemical Society. 134: 6916-9. PMID 22497214 DOI: 10.1021/Ja300500A  0.301
2012 Du J, Teng RJ, Lawrence M, Guan T, Xu H, Ge Y, Shi Y. The protein partners of GTP cyclohydrolase I in rat organs. Plos One. 7: e33991. PMID 22479495 DOI: 10.1371/Journal.Pone.0033991  0.348
2012 Oliveira SM, Zhang YH, Solis RS, Isackson H, Bellahcene M, Yavari A, Pinter K, Davies JK, Ge Y, Ashrafian H, Walker JW, Carling D, Watkins H, Casadei B, Redwood C. AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes. Circulation Research. 110: 1192-201. PMID 22456184 DOI: 10.1161/Circresaha.111.259952  0.371
2012 Peng Y, Chen X, Sato T, Rankin SA, Tsuji RF, Ge Y. Purification and high-resolution top-down mass spectrometric characterization of human salivary α-amylase. Analytical Chemistry. 84: 3339-46. PMID 22390166 DOI: 10.1021/Ac300083Y  0.459
2012 Wang Y, Pinto JR, Solis RS, Dweck D, Liang J, Diaz-Perez Z, Ge Y, Walker JW, Potter JD. Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy. The Journal of Biological Chemistry. 287: 2156-67. PMID 22086914 DOI: 10.1074/Jbc.M111.294306  0.323
2012 Dong X, Sumandea CA, Chen YC, Garcia-Cazarin ML, Zhang J, Balke CW, Sumandea MP, Ge Y. Augmented phosphorylation of cardiac troponin I in hypertensive heart failure Journal of Biological Chemistry. 287: 848-857. PMID 22052912 DOI: 10.1074/Jbc.M111.293258  0.398
2011 Zhang H, Ge Y. Comprehensive analysis of protein modifications by top-down mass spectrometry. Circulation. Cardiovascular Genetics. 4: 711. PMID 22187450 DOI: 10.1161/Circgenetics.110.957829  0.527
2011 Zhang J, Guy MJ, Norman HS, Chen YC, Xu Q, Dong X, Guner H, Wang S, Kohmoto T, Young KH, Moss RL, Ge Y. Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. Journal of Proteome Research. 10: 4054-65. PMID 21751783 DOI: 10.1021/Pr200258M  0.405
2011 Zhang J, Zhang H, Ayaz-Guner S, Chen YC, Dong X, Xu Q, Ge Y. Phosphorylation, but not alternative splicing or proteolytic degradation, is conserved in human and mouse cardiac troponin T. Biochemistry. 50: 6081-92. PMID 21639091 DOI: 10.1021/Bi2006256  0.507
2011 Sancho Solis R, Ge Y, Walker JW. A preferred AMPK phosphorylation site adjacent to the inhibitory loop of cardiac and skeletal troponin I. Protein Science : a Publication of the Protein Society. 20: 894-907. PMID 21416543 DOI: 10.1002/Pro.623  0.412
2011 Kuhn P, Chumanov R, Wang Y, Ge Y, Burgess RR, Xu W. Automethylation of CARM1 allows coupling of transcription and mRNA splicing. Nucleic Acids Research. 39: 2717-26. PMID 21138967 DOI: 10.1093/Nar/Gkq1246  0.301
2011 Xu F, Xu Q, Dong X, Guy M, Guner H, Hacker TA, Ge Y. Top-down high-resolution electron capture dissociation mass spectrometry for comprehensive characterization of post-translational modifications in Rhesus monkey cardiac troponin i International Journal of Mass Spectrometry. 305: 95-102. DOI: 10.1016/J.Ijms.2010.09.007  0.509
2010 Nelson CA, Szczech JR, Dooley CJ, Xu Q, Lawrence MJ, Zhu H, Jin S, Ge Y. Effective enrichment and mass spectrometry analysis of phosphopeptides using mesoporous metal oxide nanomaterials. Analytical Chemistry. 82: 7193-201. PMID 20704311 DOI: 10.1021/Ac100877A  0.436
2010 Zhang J, Dong X, Hacker TA, Ge Y. Deciphering modifications in swine cardiac troponin I by top-down high-resolution tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 21: 940-8. PMID 20223681 DOI: 10.1016/J.Jasms.2010.02.005  0.487
2009 Nelson CA, Szczech JR, Xu Q, Lawrence MJ, Jin S, Ge Y. Mesoporous zirconium oxide nanomaterials effectively enrich phosphopeptides for mass spectrometry-based phosphoproteomics. Chemical Communications (Cambridge, England). 6607-9. PMID 19865665 DOI: 10.1039/B908788E  0.306
2009 Ayaz-Guner S, Zhang J, Li L, Walker JW, Ge Y. In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated. Biochemistry. 48: 8161-70. PMID 19637843 DOI: 10.1021/Bi900739F  0.452
2009 Ge Y, Rybakova IN, Xu Q, Moss RL. Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state. Proceedings of the National Academy of Sciences of the United States of America. 106: 12658-63. PMID 19541641 DOI: 10.1073/Pnas.0813369106  0.487
2009 Kuhn P, Xu Q, Cline E, Zhang D, Ge Y, Xu W. Delineating Anopheles gambiae coactivator associated arginine methyltransferase 1 automethylation using top-down high resolution tandem mass spectrometry. Protein Science : a Publication of the Protein Society. 18: 1272-80. PMID 19472346 DOI: 10.1002/Pro.139  0.417
2009 Ma M, Chen R, Ge Y, He H, Marshall AG, Li L. Combining bottom-up and top-down mass spectrometric strategies for de novo sequencing of the crustacean hyperglycemic hormone from Cancer borealis. Analytical Chemistry. 81: 240-7. PMID 19046072 DOI: 10.1021/Ac801910G  0.414
2009 Solis RS, Ge Y, Walker JW. High Resolution Top-Down MS/MS Reveals Single Amino Acid Sequence Polymorphisms in Rat Cardiac Troponin Biophysical Journal. 96: 503a. DOI: 10.1016/J.Bpj.2008.12.2592  0.483
2008 Sancho Solis R, Ge Y, Walker JW. Single amino acid sequence polymorphisms in rat cardiac troponin revealed by top-down tandem mass spectrometry. Journal of Muscle Research and Cell Motility. 29: 203-12. PMID 19165611 DOI: 10.1007/S10974-009-9168-Y  0.469
2008 Zabrouskov V, Ge Y, Schwartz J, Walker JW. Unraveling molecular complexity of phosphorylated human cardiac troponin I by top down electron capture dissociation/electron transfer dissociation mass spectrometry. Molecular & Cellular Proteomics : McP. 7: 1838-49. PMID 18445579 DOI: 10.1074/Mcp.M700524-Mcp200  0.472
2005 Colabroy KL, Zhai H, Li T, Ge Y, Zhang Y, Liu A, Ealick SE, McLafferty FW, Begley TP. The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate. Biochemistry. 44: 7623-31. PMID 15909977 DOI: 10.1021/Bi0473455  0.65
2003 Ge Y, Lawhorn BG, ElNaggar M, Sze SK, Begley TP, McLafferty FW. Detection of four oxidation sites in viral prolyl-4-hydroxylase by top-down mass spectrometry. Protein Science : a Publication of the Protein Society. 12: 2320-6. PMID 14500890 DOI: 10.1110/Ps.03244403  0.801
2003 Sze SK, Ge Y, Oh H, McLafferty FW. Plasma electron capture dissociation for the characterization of large proteins by top down mass spectrometry. Analytical Chemistry. 75: 1599-603. PMID 12705591 DOI: 10.1021/Ac020446T  0.491
2003 Ge Y, El-Naggar M, Sze SK, Oh HB, Begley TP, McLafferty FW, Boshoff H, Barry CE. Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry. Journal of the American Society For Mass Spectrometry. 14: 253-61. PMID 12648932 DOI: 10.1016/S1044-0305(02)00913-3  0.694
2002 Oh H, Breuker K, Sze SK, Ge Y, Carpenter BK, McLafferty FW. Secondary and tertiary structures of gaseous protein ions characterized by electron capture dissociation mass spectrometry and photofragment spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 99: 15863-8. PMID 12444260 DOI: 10.1073/Pnas.212643599  0.501
2002 Sze SK, Ge Y, Oh H, McLafferty FW. Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue. Proceedings of the National Academy of Sciences of the United States of America. 99: 1774-9. PMID 11842225 DOI: 10.1073/Pnas.251691898  0.548
2002 Ge Y, Lawhorn BG, ElNaggar M, Strauss E, Park JH, Begley TP, McLafferty FW. Top down characterization of larger proteins (45 kDa) by electron capture dissociation mass spectrometry. Journal of the American Chemical Society. 124: 672-8. PMID 11804498 DOI: 10.1021/Ja011335Z  0.831
2001 Xi J, Ge Y, Kinsland C, McLafferty FW, Begley TP. Biosynthesis of the thiazole moiety of thiamin in Escherichia coli: identification of an acyldisulfide-linked protein--protein conjugate that is functionally analogous to the ubiquitin/E1 complex. Proceedings of the National Academy of Sciences of the United States of America. 98: 8513-8. PMID 11438688 DOI: 10.1073/Pnas.141226698  0.814
2001 McLafferty FW, Horn DM, Breuker K, Ge Y, Lewis MA, Cerda B, Zubarev RA, Carpenter BK. Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance. Journal of the American Society For Mass Spectrometry. 12: 245-9. PMID 11281599 DOI: 10.1016/S1044-0305(00)00223-3  0.595
2001 Strauss E, Kinsland C, Ge Y, McLafferty FW, Begley TP. Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria. The Journal of Biological Chemistry. 276: 13513-6. PMID 11278255 DOI: 10.1074/Jbc.C100033200  0.772
2001 Ge Y, Horn DM, McLafferty FW. Blackbody infrared radiative dissociation of larger (42 kDa) multiply charged proteins International Journal of Mass Spectrometry. 210: 203-214. DOI: 10.1016/S1387-3806(01)00394-3  0.615
2000 Horn DM, Ge Y, McLafferty FW. Activated ion electron capture dissociation for mass spectral sequencing of larger (42 kDa) proteins. Analytical Chemistry. 72: 4778-84. PMID 11055690 DOI: 10.1021/Ac000494I  0.641
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