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Aarron Willingham - Publications

Affiliations: 
Merck & Co. 
Area:
biologics discovery and cell-based assays
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Sukumar S, Wilson DC, Yu Y, Wong J, Naravula S, Ermakov G, Riener R, Bhagwat B, Necheva AS, Grein J, Churakova T, Mangadu R, Georgiev P, Manfra D, Pinheiro EM, ... ... Willingham A, et al. Characterization of MK-4166, a clinical agonistic antibody that targets human GITR and inhibits the generation and suppressive effects of T regulatory cells. Cancer Research. PMID 28611044 DOI: 10.1158/0008-5472.Can-16-1439  0.3
2012 Kenski DM, Butora G, Willingham AT, Cooper AJ, Fu W, Qi N, Soriano F, Davies IW, Flanagan WM. siRNA-optimized Modifications for Enhanced In Vivo Activity. Molecular Therapy. Nucleic Acids. 1: e5. PMID 23344622 DOI: 10.1038/Mtna.2011.4  0.579
2012 Chorn G, Klein-McDowell M, Zhao L, Saunders MA, Flanagan WM, Willingham AT, Lim LP. Single-stranded microRNA mimics. Rna (New York, N.Y.). 18: 1796-804. PMID 22912485 DOI: 10.1261/rna.031278.111  0.609
2012 Fucini RV, Haringsma HJ, Deng P, Flanagan WM, Willingham AT. Adenosine modification may be preferred for reducing siRNA immune stimulation. Nucleic Acid Therapeutics. 22: 205-10. PMID 22519815 DOI: 10.1089/nat.2011.0334  0.615
2012 Kenski DM, Willingham AT, Haringsma HJ, Li JJ, Flanagan WM. In vivo activity and duration of short interfering RNAs containing a synthetic 5'-phosphate. Nucleic Acid Therapeutics. 22: 90-5. PMID 22400991 DOI: 10.1089/Nat.2011.0333  0.634
2012 Haringsma HJ, Li JJ, Soriano F, Kenski DM, Flanagan WM, Willingham AT. mRNA knockdown by single strand RNA is improved by chemical modifications. Nucleic Acids Research. 40: 4125-36. PMID 22253019 DOI: 10.1093/Nar/Gkr1301  0.661
2011 Peacock H, Fucini RV, Jayalath P, Ibarra-Soza JM, Haringsma HJ, Flanagan WM, Willingham A, Beal PA. Nucleobase and ribose modifications control immunostimulation by a MicroRNA-122-mimetic RNA Journal of the American Chemical Society. 133: 9200-9203. PMID 21612237 DOI: 10.1021/Ja202492E  0.64
2011 Graveley BR, Brooks AN, Carlson JW, Duff MO, Landolin JM, Yang L, Artieri CG, van Baren MJ, Boley N, Booth BW, Brown JB, Cherbas L, Davis CA, Dobin A, Li R, ... ... Willingham A, et al. The developmental transcriptome of Drosophila melanogaster. Nature. 471: 473-9. PMID 21179090 DOI: 10.1038/Nature09715  0.652
2011 Cherbas L, Willingham A, Zhang D, Yang L, Zou Y, Eads BD, Carlson JW, Landolin JM, Kapranov P, Dumais J, Samsonova A, Choi JH, Roberts J, Davis CA, Tang H, et al. The transcriptional diversity of 25 Drosophila cell lines. Genome Research. 21: 301-14. PMID 21177962 DOI: 10.1101/Gr.112961.110  0.561
2010 Kenski DM, Cooper AJ, Li JJ, Willingham AT, Haringsma HJ, Young TA, Kuklin NA, Jones JJ, Cancilla MT, McMasters DR, Mathur M, Sachs AB, Flanagan WM. Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo. Nucleic Acids Research. 38: 660-71. PMID 19917641 DOI: 10.1093/Nar/Gkp913  0.647
2007 Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, Stadler PF, Hertel J, Hackermüller J, Hofacker IL, Bell I, Cheung E, Drenkow J, Dumais E, Patel S, et al. RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science (New York, N.Y.). 316: 1484-8. PMID 17510325 DOI: 10.1126/Science.1138341  0.682
2007 Kapranov P, Willingham AT, Gingeras TR. Genome-wide transcription and the implications for genomic organization. Nature Reviews. Genetics. 8: 413-23. PMID 17486121 DOI: 10.1038/Nrg2083  0.575
2006 Willingham AT, Gingeras TR. TUF love for "junk" DNA. Cell. 125: 1215-20. PMID 16814704 DOI: 10.1016/J.Cell.2006.06.009  0.656
2005 Willingham AT, Orth AP, Batalov S, Peters EC, Wen BG, Aza-Blanc P, Hogenesch JB, Schultz PG. A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science (New York, N.Y.). 309: 1570-3. PMID 16141075 DOI: 10.1126/Science.1115901  0.718
2004 Willingham AT, Deveraux QL, Hampton GM, Aza-Blanc P. RNAi and HTS: exploring cancer by systematic loss-of-function. Oncogene. 23: 8392-400. PMID 15517021 DOI: 10.1038/sj.onc.1208217  0.59
2004 Willingham AT, Keil T. A tissue specific cytochrome P450 required for the structure and function of Drosophila sensory organs. Mechanisms of Development. 121: 1289-97. PMID 15327788 DOI: 10.1016/S0925-4773(04)00098-X  0.559
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