Chunhui Xu - Publications

Affiliations: 
Georgia Tech/Emory, Atlanta, GA, United States 
Area:
stem cell biology, cardiology

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Forghani P, Rashid A, Armand LC, Wolfson D, Liu R, Cho HC, Maxwell JT, Jo H, Salaita K, Xu C. Simulated microgravity improves maturation of cardiomyocytes derived from human induced pluripotent stem cells. Scientific Reports. 14: 2243. PMID 38278855 DOI: 10.1038/s41598-024-52453-1  0.359
2023 Hwang H, Rampoldi A, Forghani P, Li D, Fite J, Boland G, Maher K, Xu C. Space microgravity increases expression of genes associated with proliferation and differentiation in human cardiac spheres. Npj Microgravity. 9: 88. PMID 38071377 DOI: 10.1038/s41526-023-00336-6  0.404
2023 Xu CH, Chen X, Zhu GQ, Yi HM, Chen SL, Liu T, Yu YT, Zhang QH, Jiang EL, Feng SZ. Diagnostic performance and clinical impacts of metagenomic sequencing after allogeneic hematopoietic stem cell transplantation. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. PMID 38065767 DOI: 10.1016/j.jmii.2023.11.002  0.33
2023 Li D, Armand LC, Sun F, Hwang H, Wolfson D, Rampoldi A, Liu R, Forghani P, Hu X, Yu WM, Qu CK, Jones DP, Wu R, Cho HC, Maxwell JT, ... Xu C, et al. AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling. Stem Cell Research & Therapy. 14: 322. PMID 37941041 DOI: 10.1186/s13287-023-03554-7  0.425
2023 Fei MY, Wang Y, Chang BH, Xue K, Dong F, Huang D, Li XY, Li ZJ, Hu CL, Liu P, Wu JC, Yu PC, Hong MH, Chen SB, Xu CH, et al. The cell non-autonomous function of ID1 promotes AML progression via ANGPTL7 from the microenvironment. Blood. PMID 37319434 DOI: 10.1182/blood.2022019537  0.35
2022 Rampoldi A, Forghani P, Li D, Hwang H, Armand LC, Fite J, Boland G, Maxwell J, Maher K, Xu C. Space microgravity improves proliferation of human iPSC-derived cardiomyocytes. Stem Cell Reports. PMID 36084640 DOI: 10.1016/j.stemcr.2022.08.007  0.413
2021 Sart S, Liu C, Zeng EZ, Xu C, Li Y. Downstream bioprocessing of human pluripotent stem cell-derived therapeutics. Engineering in Life Sciences. 22: 667-680. PMID 36348655 DOI: 10.1002/elsc.202100042  0.423
2021 Forghani P, Rashid A, Sun F, Liu R, Li D, Lee MR, Hwang H, Maxwell JT, Mandawat A, Wu R, Salaita K, Xu C. Carfilzomib Treatment Causes Molecular and Functional Alterations of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Journal of the American Heart Association. e022247. PMID 34873922 DOI: 10.1161/JAHA.121.022247  0.337
2021 Rampoldi A, Jha R, Fite J, Boland G, Xu C. Cryopreservation and CO-independent culture of 3D cardiac progenitors for spaceflight experiments. Biomaterials. 269: 120673. PMID 33493770 DOI: 10.1016/j.biomaterials.2021.120673  0.435
2020 Liu R, Li D, Sun F, Rampoldi A, Maxwell JT, Wu R, Fischbach P, Castellino SM, Du Y, Fu H, Mandawat A, Xu C. Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells. Stem Cell Research & Therapy. 11: 470. PMID 33153480 DOI: 10.1186/s13287-020-01984-1  0.435
2020 Jha R, Li D, Wu Q, Ferguson KE, Forghani P, Gibson GC, Xu C. A long non-coding RNA GATA6-AS1 adjacent to GATA6 is required for cardiomyocyte differentiation from human pluripotent stem cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32888237 DOI: 10.1096/Fj.202000206R  0.523
2019 Saraf A, Book W, Nelson TJ, Xu C. Hypoplastic left heart syndrome: From bedside to bench and back. Journal of Molecular and Cellular Cardiology. PMID 31419439 DOI: 10.1016/j.yjmcc.2019.08.005  0.313
2019 Rampoldi A, Singh M, Wu Q, Duan M, Jha R, Maxwell JT, Bradner JM, Zhang X, Saraf A, Miller GW, Gibson G, Brown LA, Xu C. Cardiac Toxicity From Ethanol Exposure in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 169: 280-292. PMID 31059573 DOI: 10.1093/Toxsci/Kfz038  0.413
2018 Trac D, Maxwell JT, Brown ME, Xu C, Davis ME. Aggregation of Child Cardiac Progenitor Cells into Spheres Activates Notch Signaling and Improves Treatment of Right Ventricular Heart Failure. Circulation Research. PMID 30590978 DOI: 10.1161/Circresaha.118.313845  0.42
2018 Rampoldi A, Crooke SN, Preininger MK, Jha R, Maxwell J, Ding L, Spearman P, Finn MG, Xu C. Targeted Elimination of Tumorigenic Human Pluripotent Stem Cells Using Suicide-inducing Virus-like Particles. Acs Chemical Biology. PMID 29979576 DOI: 10.1021/Acschembio.8B00490  0.412
2018 Maxwell JT, Xu C. Stem-Cell-Derived Cardiomyocytes Grow Up: Start Young and Train Harder. Cell Stem Cell. 22: 790-791. PMID 29859168 DOI: 10.1016/J.Stem.2018.05.011  0.493
2018 Zhang YL, Sun JW, Xie YY, Zhou Y, Liu P, Song JC, Xu CH, Wang L, Liu D, Xu AN, Chen Z, Chen SJ, Sun XJ, Huang QH. Setd2 deficiency impairs hematopoietic stem cell self-renewal and causes malignant transformation. Cell Research. PMID 29531312 DOI: 10.1038/s41422-018-0015-9  0.343
2018 Nachlas ALY, Li S, Jha R, Singh M, Xu C, Davis ME. Human iPSC-derived mesenchymal stem cells matured into valve interstitial-like cells using PEGDA hydrogels. Acta Biomaterialia. PMID 29505894 DOI: 10.1016/J.Actbio.2018.02.025  0.536
2018 Gentillon C, Duan M, Yu W, Jha R, Li S, Liang B, Todor A, Gibson G, Qu C, Brown LA, Xu C. Abstract 278: Dual Modulation of Microscale Tissue Engineering and Energy Metabolism for Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.278  0.461
2017 Jha R, Singh M, Wu Q, Gentillon C, Preininger MK, Xu C. Downregulation of LGR5 Expression Inhibits Cardiomyocyte Differentiation and Potentiates Endothelial Differentiation from Human Pluripotent Stem Cells. Stem Cell Reports. 9: 513-527. PMID 28793247 DOI: 10.1016/J.Stemcr.2017.07.006  0.544
2017 Bylund J, Awgulewitsch CP, Trinh LT, Paik DT, Jetter C, Jha R, Zhang J, Nolan K, Xu C, Thompson T, Kamp TJ, Hatzopoulos AK. Coordinated proliferation and differentiation of human iPS cell-derived cardiac progenitor cells depends on BMP signaling regulation by Gremlin 2. Stem Cells and Development. PMID 28125926 DOI: 10.1089/Scd.2016.0226  0.581
2016 Preininger MK, Singh M, Xu C. Cryopreservation of Human Pluripotent Stem Cell-Derived Cardiomyocytes: Strategies, Challenges, and Future Directions. Advances in Experimental Medicine and Biology. 951: 123-135. PMID 27837559 DOI: 10.1007/978-3-319-45457-3_10  0.526
2016 Han J, Qian X, Wu Q, Jha R, Duan J, Yang Z, Maher KO, Nie S, Xu C. Novel surface-enhanced Raman scattering-based assays for ultra-sensitive detection of human pluripotent stem cells. Biomaterials. 105: 66-76. PMID 27509304 DOI: 10.1016/J.Biomaterials.2016.07.033  0.52
2016 Jha R, Wu Q, Singh M, Preininger MK, Han P, Ding G, Cho HC, Jo H, Maher KO, Wagner MB, Xu C. Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells. Scientific Reports. 6: 30956. PMID 27492371 DOI: 10.1038/Srep30956  0.555
2016 Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin ZT, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C. A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses. Disease Models & Mechanisms. PMID 27491078 DOI: 10.1242/Dmm.026823  0.344
2016 Han J, Wu Q, Xia Y, Wagner MB, Xu C. Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation. Stem Cell Research. 16: 740-750. PMID 27131761 DOI: 10.1016/J.Scr.2016.04.014  0.438
2015 Jha R, Xu RH, Xu C. Efficient differentiation of cardiomyocytes from human pluripotent stem cells with growth factors. Methods in Molecular Biology (Clifton, N.J.). 1299: 115-31. PMID 25836579 DOI: 10.1007/978-1-4939-2572-8_9  0.569
2015 Jha R, Wile B, Wu Q, Morris AH, Maher KO, Wagner MB, Bao G, Xu C. Molecular beacon-based detection and isolation of working-type cardiomyocytes derived from human pluripotent stem cells. Biomaterials. 50: 176-85. PMID 25736507 DOI: 10.1016/J.Biomaterials.2015.01.043  0.481
2014 Nguyen DC, Hookway TA, Wu Q, Jha R, Preininger MK, Chen X, Easley CA, Spearman P, Deshpande SR, Maher K, Wagner MB, McDevitt TC, Xu C. Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells. Stem Cell Reports. 3: 260-8. PMID 25254340 DOI: 10.1016/J.Stemcr.2014.06.002  0.521
2014 Li Y, Xu C, Ma T. In vitro organogenesis from pluripotent stem cells. Organogenesis. 10: 159-63. PMID 24762764 DOI: 10.4161/Org.28918  0.405
2014 Hookway TA, Nguyen D, Xu C, Wagner MB, McDevitt TC. Engineering cardiospheres from human pluripotent stem cells Proceedings of the Ieee Annual Northeast Bioengineering Conference, Nebec. 2014. DOI: 10.1109/NEBEC.2014.6972817  0.49
2013 Maher KO, Xu C. Marching towards regenerative cardiac therapy with human pluripotent stem cells. Discovery Medicine. 15: 349-56. PMID 23819949  0.54
2012 Xu C. Turning cardiac fibroblasts into cardiomyocytes in vivo. Trends in Molecular Medicine. 18: 575-6. PMID 22770847 DOI: 10.1016/j.molmed.2012.06.009  0.358
2012 Xu C. Differentiation and enrichment of cardiomyocytes from human pluripotent stem cells. Journal of Molecular and Cellular Cardiology. 52: 1203-12. PMID 22484618 DOI: 10.1016/j.yjmcc.2012.03.012  0.528
2011 Xu C, Police S, Hassanipour M, Li Y, Chen Y, Priest C, O'Sullivan C, Laflamme MA, Zhu WZ, Van Biber B, Hegerova L, Yang J, Delavan-Boorsma K, Davies A, Lebkowski J, et al. Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells. Regenerative Medicine. 6: 53-66. PMID 21175287 DOI: 10.2217/Rme.10.91  0.591
2010 Xu C. Progress and prospects of human pluripotent stem cell research. Current Stem Cell Research & Therapy. 5: 205-6. PMID 20618147 DOI: 10.2174/157488810791824566  0.415
2009 Zhu WZ, Hauch KD, Xu C, Laflamme MA. Human embryonic stem cells and cardiac repair. Transplantation Reviews (Orlando, Fla.). 23: 53-68. PMID 18657407 DOI: 10.1016/J.Trre.2008.05.005  0.577
2007 Laflamme MA, Chen KY, Naumova AV, Muskheli V, Fugate JA, Dupras SK, Reinecke H, Xu C, Hassanipour M, Police S, O'Sullivan C, Collins L, Chen Y, Minami E, Gill EA, et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nature Biotechnology. 25: 1015-24. PMID 17721512 DOI: 10.1038/Nbt1327  0.643
2006 Xu C, Lebkowski J, Gold JD. Growth and differentiation of human embryonic stem cells for cardiac cell replacement therapy. Current Stem Cell Research & Therapy. 1: 173-87. PMID 18220865 DOI: 10.2174/157488806776956931  0.607
2006 Xu C, He JQ, Kamp TJ, Police S, Hao X, O'Sullivan C, Carpenter MK, Lebkowski J, Gold JD. Human embryonic stem cell-derived cardiomyocytes can be maintained in defined medium without serum. Stem Cells and Development. 15: 931-41. PMID 17253954 DOI: 10.1089/Scd.2006.15.931  0.524
2006 Xu C. Characterization and evaluation of human embryonic stem cells. Methods in Enzymology. 420: 18-37. PMID 17161691 DOI: 10.1016/S0076-6879(06)20002-8  0.508
2006 Xu C, Police S, Hassanipour M, Gold JD. Cardiac bodies: a novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells. Stem Cells and Development. 15: 631-9. PMID 17105398 DOI: 10.1089/Scd.2006.15.631  0.564
2006 Kofidis T, Lebl DR, Swijnenburg RJ, Greeve JM, Klima U, Gold J, Xu C, Robbins RC. Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 29: 50-5. PMID 16337396 DOI: 10.1016/J.Ejcts.2005.10.015  0.54
2006 Kofidis T, Lebl DR, Swijnenburg R, Greeve JM, Klima U, Gold J, Xu C, Robbins RC. Corrigendum to “Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury” [Eur J Cardiothorac Surg 29 (2006) 50–55] European Journal of Cardio-Thoracic Surgery. 29: 1069-1069. DOI: 10.1093/Ejcts/29.6.1069  0.31
2005 Laflamme MA, Gold J, Xu C, Hassanipour M, Rosler E, Police S, Muskheli V, Murry CE. Formation of human myocardium in the rat heart from human embryonic stem cells. The American Journal of Pathology. 167: 663-71. PMID 16127147 DOI: 10.1016/S0002-9440(10)62041-X  0.614
2005 Xu C, Rosler E, Jiang J, Lebkowski JS, Gold JD, O'Sullivan C, Delavan-Boorsma K, Mok M, Bronstein A, Carpenter MK. Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium. Stem Cells (Dayton, Ohio). 23: 315-23. PMID 15749926 DOI: 10.1634/Stemcells.2004-0211  0.457
2004 Xu C, Jiang J, Sottile V, McWhir J, Lebkowski J, Carpenter MK. Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth. Stem Cells (Dayton, Ohio). 22: 972-80. PMID 15536188 DOI: 10.1634/Stemcells.22-6-972  0.572
2004 Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nature Biotechnology. 22: 707-16. PMID 15146197 DOI: 10.1038/Nbt971  0.499
2002 Xu C, Police S, Rao N, Carpenter MK. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circulation Research. 91: 501-8. PMID 12242268 DOI: 10.1161/01.Res.0000035254.80718.91  0.585
2001 Lebkowski JS, Gold J, Xu C, Funk W, Chiu CP, Carpenter MK. Human embryonic stem cells: culture, differentiation, and genetic modification for regenerative medicine applications. Cancer Journal (Sudbury, Mass.). 7: S83-93. PMID 11777269  0.478
2001 Xu C, Inokuma MS, Denham J, Golds K, Kundu P, Gold JD, Carpenter MK. Feeder-free growth of undifferentiated human embryonic stem cells. Nature Biotechnology. 19: 971-4. PMID 11581665 DOI: 10.1038/Nbt1001-971  0.522
1998 Xu C, Liguori G, Adamson ED, Persico MG. Specific Arrest of Cardiogenesis in Cultured Embryonic Stem Cells Lacking Cripto-1 Developmental Biology. 196: 237-247. PMID 9576836 DOI: 10.1006/Dbio.1998.8862  0.496
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