Mikko J. Frilander - Publications

Affiliations: 
University of Helsinki, Helsingfors, Finland 
Area:
mRNA processing, RNA splicing, RNA biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Norppa AJ, Chowdhury I, van Rooijen LE, Ravantti JJ, Snel B, Varjosalo M, Frilander MJ. Distinct functions for the paralogous RBM41 and U11/U12-65K proteins in the minor spliceosome. Nucleic Acids Research. PMID 38499487 DOI: 10.1093/nar/gkae070  0.307
2021 Akinyi MV, Frilander MJ. At the Intersection of Major and Minor Spliceosomes: Crosstalk Mechanisms and Their Impact on Gene Expression. Frontiers in Genetics. 12: 700744. PMID 34354740 DOI: 10.3389/fgene.2021.700744  0.316
2020 Frilander MJ, Barborič M. The Interlocking Lives of LARP7: Fine-Tuning Transcription, RNA Modification, and Splicing through Multiple Non-coding RNAs. Molecular Cell. 78: 5-8. PMID 32243831 DOI: 10.1016/J.Molcel.2020.03.015  0.348
2019 Viita T, Kyheröinen S, Prajapati B, Virtanen J, Frilander MJ, Varjosalo M, Vartiainen MK. Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing. Journal of Cell Science. PMID 30890647 DOI: 10.1242/Jcs.226852  0.325
2018 Oghabian A, Greco D, Frilander MJ. IntEREst: intron-exon retention estimator. Bmc Bioinformatics. 19: 130. PMID 29642843 DOI: 10.1186/S12859-018-2122-5  0.344
2017 Norppa AJ, Kauppala TM, Heikkinen HA, Verma B, Iwai H, Frilander MJ. Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA. Rna (New York, N.Y.). PMID 29255062 DOI: 10.1261/Rna.062844.117  0.374
2017 Verma B, Akinyi MV, Norppa AJ, Frilander MJ. Minor spliceosome and disease. Seminars in Cell & Developmental Biology. PMID 28965864 DOI: 10.1016/J.Semcdb.2017.09.036  0.337
2017 Verbeeren J, Verma B, Niemelä EH, Yap K, Makeyev EV, Frilander MJ. Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA. Plos Genetics. 13: e1006824. PMID 28549066 DOI: 10.1371/Journal.Pgen.1006824  0.4
2017 Susi H, Laine AL, Filloux D, Kraberger S, Farkas K, Bernardo P, Frilander MJ, Martin DP, Varsani A, Roumagnac P. Genome sequences of a capulavirus infecting Plantago lanceolata in the Åland archipelago of Finland. Archives of Virology. PMID 28283818 DOI: 10.1007/S00705-017-3298-0  0.306
2017 Orsini L, Gilbert D, Podicheti R, Jansen M, Brown JB, Solari OS, Spanier KI, Colbourne JK, Rusch DB, Decaestecker E, Asselman J, De Schamphelaere KA, Ebert D, Haag CR, Kvist J, ... ... Frilander MJ, et al. Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors. Scientific Data. 4: 170006. PMID 28140384 DOI: 10.1038/Sdata.2017.6  0.36
2017 Ahola V, Wahlberg N, Frilander MJ. Butterfly Genomics: Insights from the Genome ofMelitaea cinxia Annales Zoologici Fennici. 54: 275-291. DOI: 10.5735/086.054.0123  0.309
2016 Känsäkoski J, Jääskeläinen J, Jääskeläinen T, Tommiska J, Saarinen L, Lehtonen R, Hautaniemi S, Frilander MJ, Palvimo JJ, Toppari J, Raivio T. Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene. Scientific Reports. 6: 32819. PMID 27609317 DOI: 10.1038/Srep32819  0.336
2016 Orsini L, Gilbert D, Podicheti R, Jansen M, Brown JB, Solari OS, Spanier KI, Colbourne JK, Rush D, Decaestecker E, Asselman J, De Schamphelaere KA, Ebert D, Haag CR, Kvist J, ... ... Frilander MJ, et al. Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors. Scientific Data. 3: 160030. PMID 27164179 DOI: 10.1038/Sdata.2016.30  0.365
2015 Niemelä EH, Verbeeren J, Singha P, Nurmi V, Frilander MJ. Evolutionarily conserved exon definition interactions with U11 snRNP mediate alternative splicing regulation on U11-48K and U11/U12-65K genes. Rna Biology. 12: 1256-64. PMID 26479860 DOI: 10.1080/15476286.2015.1096489  0.422
2015 Kvist J, Mattila AL, Somervuo P, Ahola V, Koskinen P, Paulin L, Salmela L, Fountain T, Rastas P, Ruokolainen A, Taipale M, Holm L, Auvinen P, Lehtonen R, Frilander MJ, et al. Flight-induced changes in gene expression in the Glanville fritillary butterfly. Molecular Ecology. 24: 4886-900. PMID 26331775 DOI: 10.1111/Mec.13359  0.359
2014 Niemelä EH, Frilander MJ. Regulation of gene expression through inefficient splicing of U12-type introns. Rna Biology. 11: 1325-9. PMID 25692230 DOI: 10.1080/15476286.2014.996454  0.407
2014 Somervuo P, Kvist J, Ikonen S, Auvinen P, Paulin L, Koskinen P, Holm L, Taipale M, Duplouy A, Ruokolainen A, Saarnio S, Sirén J, Kohonen J, Corander J, Frilander MJ, et al. Transcriptome analysis reveals signature of adaptation to landscape fragmentation. Plos One. 9: e101467. PMID 24988207 DOI: 10.1371/Journal.Pone.0101467  0.346
2014 Niemelä EH, Oghabian A, Staals RHJ, Greco D, Pruijn GJM, Frilander MJ. Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome Nucleic Acids Research. 42: 7358-7369. PMID 24848017 DOI: 10.1093/Nar/Gku391  0.437
2014 Argente J, Flores R, Gutiérrez-Arumí A, Verma B, Martos-Moreno GÁ, Cuscó I, Oghabian A, Chowen JA, Frilander MJ, Pérez-Jurado LA. Defective minor spliceosome mRNA processing results in isolated familial growth hormone deficiency. Embo Molecular Medicine. 6: 299-306. PMID 24480542 DOI: 10.1002/Emmm.201303573  0.351
2013 Turunen JJ, Verma B, Nyman TA, Frilander MJ. HnRNPH1/H2, U1 snRNP, and U11 snRNP cooperate to regulate the stability of the U11-48K pre-mRNA. Rna (New York, N.Y.). 19: 380-9. PMID 23335637 DOI: 10.1261/Rna.036715.112  0.422
2013 Turunen JJ, Niemelä EH, Verma B, Frilander MJ. The significant other: splicing by the minor spliceosome. Wiley Interdisciplinary Reviews. Rna. 4: 61-76. PMID 23074130 DOI: 10.1002/Wrna.1141  0.452
2011 Pessa HK, Frilander MJ. Genetics. Minor splicing, disrupted. Science (New York, N.Y.). 332: 184-5. PMID 21474744 DOI: 10.1126/Science.1205503  0.377
2011 Wheat CW, Fescemyer HW, Kvist J, Tas E, Vera JC, Frilander MJ, Hanski I, Marden JH. Functional genomics of life history variation in a butterfly metapopulation. Molecular Ecology. 20: 1813-28. PMID 21410806 DOI: 10.1111/J.1365-294X.2011.05062.X  0.309
2011 Helenius K, Yang Y, Tselykh TV, Pessa HK, Frilander MJ, Mäkelä TP. Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover. Nucleic Acids Research. 39: 5025-35. PMID 21385826 DOI: 10.1093/Nar/Gkr107  0.35
2010 Pessa HK, Greco D, Kvist J, Wahlström G, Heino TI, Auvinen P, Frilander MJ. Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathways. Plos One. 5: e13215. PMID 20949011 DOI: 10.1371/Journal.Pone.0013215  0.406
2010 Verbeeren J, Niemelä EH, Turunen JJ, Will CL, Ravantti JJ, Lührmann R, Frilander MJ. An ancient mechanism for splicing control: U11 snRNP as an activator of alternative splicing. Molecular Cell. 37: 821-33. PMID 20347424 DOI: 10.1016/J.Molcel.2010.02.014  0.436
2009 Orsini L, Wheat CW, Haag CR, Kvist J, Frilander MJ, Hanski I. Fitness differences associated with Pgi SNP genotypes in the Glanville fritillary butterfly (Melitaea cinxia). Journal of Evolutionary Biology. 22: 367-75. PMID 19032494 DOI: 10.1111/J.1420-9101.2008.01653.X  0.301
2008 Paatero AO, Turakainen H, Happonen LJ, Olsson C, Palomäki T, Pajunen MI, Meng X, Otonkoski T, Tuuri T, Berry C, Malani N, Frilander MJ, Bushman FD, Savilahti H. Bacteriophage Mu integration in yeast and mammalian genomes. Nucleic Acids Research. 36: e148. PMID 18953026 DOI: 10.1093/Nar/Gkn801  0.377
2008 Pessa HK, Will CL, Meng X, Schneider C, Watkins NJ, Perälä N, Nymark M, Turunen JJ, Lührmann R, Frilander MJ. Minor spliceosome components are predominantly localized in the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 105: 8655-60. PMID 18559850 DOI: 10.1073/Pnas.0803646105  0.339
2008 Turunen JJ, Will CL, Grote M, Lührmann R, Frilander MJ. The U11-48K protein contacts the 5' splice site of U12-type introns and the U11-59K protein. Molecular and Cellular Biology. 28: 3548-60. PMID 18347052 DOI: 10.1128/Mcb.01928-07  0.375
2008 Vera JC, Wheat CW, Fescemyer HW, Frilander MJ, Crawford DL, Hanski I, Marden JH. Rapid transcriptome characterization for a nonmodel organism using 454 pyrosequencing. Molecular Ecology. 17: 1636-47. PMID 18266620 DOI: 10.1111/J.1365-294X.2008.03666.X  0.359
2007 Yang J, Välineva T, Hong J, Bu T, Yao Z, Jensen ON, Frilander MJ, Silvennoinen O. Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome Nucleic Acids Research. 35: 4485-4494. PMID 17576664 DOI: 10.1093/Nar/Gkm470  0.346
2006 Pessa HK, Ruokolainen A, Frilander MJ. The abundance of the spliceosomal snRNPs is not limiting the splicing of U12-type introns. Rna (New York, N.Y.). 12: 1883-92. PMID 16957280 DOI: 10.1261/Rna.213906  0.389
2005 Frilander MJ, Meng X. Proximity of the U12 snRNA with both the 5' splice site and the branch point during early stages of spliceosome assembly. Molecular and Cellular Biology. 25: 4813-25. PMID 15923601 DOI: 10.1128/Mcb.25.12.4813-4825.2005  0.409
2004 Schneider C, Will CL, Brosius J, Frilander MJ, Lührmann R. Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 101: 9584-9. PMID 15210936 DOI: 10.1073/Pnas.0403400101  0.431
2002 Pirttimaa MJ, Paatero AO, Frilander MJ, Bamford DH. Nonspecific nucleoside triphosphatase P4 of double-stranded RNA bacteriophage phi6 is required for single-stranded RNA packaging and transcription. Journal of Virology. 76: 10122-7. PMID 12239286 DOI: 10.1128/Jvi.76.20.10122-10127.2002  0.552
2002 McConnell TS, Cho SJ, Frilander MJ, Steitz JA. Branchpoint selection in the splicing of U12-dependent introns in vitro. Rna (New York, N.Y.). 8: 579-86. PMID 12022225 DOI: 10.1017/S1355838202028029  0.591
2001 Frilander MJ, Steitz JA. Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome. Molecular Cell. 7: 217-26. PMID 11172726 DOI: 10.1016/S1097-2765(01)00169-1  0.586
1999 Frilander MJ, Steitz JA. Initial recognition of U12-dependent introns requires both U11/5' splice-site and U12/branchpoint interactions. Genes & Development. 13: 851-63. PMID 10197985 DOI: 10.1101/Gad.13.7.851  0.579
1995 Frilander M, Bamford DH. In vitro packaging of the single-stranded RNA genomic precursors of the segmented double-stranded RNA bacteriophage phi 6: the three segments modulate each other's packaging efficiency. Journal of Molecular Biology. 246: 418-28. PMID 7877165 DOI: 10.1006/Jmbi.1994.0096  0.555
1995 van Dijk AA, Frilander M, Bamford DH. Differentiation between minus- and plus-strand synthesis: polymerase activity of dsRNA bacteriophage phi 6 in an in vitro packaging and replication system. Virology. 211: 320-3. PMID 7645229 DOI: 10.1006/Viro.1995.1409  0.563
1994 Gottlieb P, Qiao X, Strassman J, Frilander M, Mindich L. Identification of the packaging regions within the genomic RNA segments of bacteriophage phi 6. Virology. 200: 42-7. PMID 8128636 DOI: 10.1006/Viro.1994.1160  0.435
1994 Mindich L, Qiao X, Onodera S, Gottlieb P, Frilander M. RNA structural requirements for stability and minus-strand synthesis in the dsRNA bacteriophage phi 6. Virology. 202: 258-63. PMID 8009837 DOI: 10.1006/Viro.1994.1341  0.405
1993 Onodera S, Qiao X, Gottlieb P, Strassman J, Frilander M, Mindich L. RNA structure and heterologous recombination in the double-stranded RNA bacteriophage phi 6. Journal of Virology. 67: 4914-22. PMID 8331732 DOI: 10.1128/Jvi.67.8.4914-4922.1993  0.414
1992 Frilander M, Gottlieb P, Strassman J, Bamford DH, Mindich L. Dependence of minus-strand synthesis on complete genomic packaging in the double-stranded RNA bacteriophage phi 6. Journal of Virology. 66: 5013-7. PMID 1629962 DOI: 10.1128/Jvi.66.8.5013-5017.1992  0.547
1992 Gottlieb P, Strassman J, Qiao X, Frilander M, Frucht A, Mindich L. In vitro packaging and replication of individual genomic segments of bacteriophage phi 6 RNA. Journal of Virology. 66: 2611-16. PMID 1560520 DOI: 10.1128/Jvi.66.5.2611-2616.1992  0.42
1991 Bamford JK, Hänninen AL, Pakula TM, Ojala PM, Kalkkinen N, Frilander M, Bamford DH. Genome organization of membrane-containing bacteriophage PRD1. Virology. 183: 658-76. PMID 1853567 DOI: 10.1016/0042-6822(91)90995-N  0.527
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