Ruben Abagyan - Related publications

Affiliations: 
Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, San Diego, La Jolla, CA 
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13 most relevant papers in past 60 days:
Year Citation  Score
2021 Schultz KJ, Colby SM, Lin VS, Wright AT, Renslow RS. Ligand- and Structure-Based Analysis of Deep Learning-Generated Potential α2a Adrenoceptor Agonists. Journal of Chemical Information and Modeling. PMID 33404240 DOI: 10.1021/acs.jcim.0c01019   
2021 Upreti S, Prusty JS, Pandey SC, Kumar A, Samant M. Identification of novel inhibitors of angiotensin-converting enzyme 2 (ACE-2) receptor from Urtica dioica to combat coronavirus disease 2019 (COVID-19). Molecular Diversity. PMID 33398633 DOI: 10.1007/s11030-020-10159-2   
2021 Lo CH, Schaaf TM, Thomas DD, Sachs JN. Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators. Methods in Molecular Biology (Clifton, N.J.). 2248: 121-137. PMID 33185872 DOI: 10.1007/978-1-0716-1130-2_9   
2021 Delfosse V, Huet T, Harrus D, Granell M, Bourguet M, Gardia-Parège C, Chiavarina B, Grimaldi M, Le Mével S, Blanc P, Huang D, Gruszczyk J, Demeneix B, Cianférani S, Fini JB, et al. Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33361153 DOI: 10.1073/pnas.2020551118   
2021 Thorat SA, Lee Y, Jung A, Ann J, Ahn S, Baek J, Zuo D, Do N, Jeong JJ, Blumberg PM, Esch TE, Turcios NA, Pearce LV, Ha HJ, Yoo YD, et al. Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift. Journal of Medicinal Chemistry. PMID 33385210 DOI: 10.1021/acs.jmedchem.0c00982   
2021 Piir G, Sild S, Maran U. Binary and multi-class classification for androgen receptor agonists, antagonists and binders. Chemosphere. 262: 128313. PMID 33182081 DOI: 10.1016/j.chemosphere.2020.128313   
2021 Li L, Hu J, Shi X, Różycki B, Song F. Interplay between cooperativity of intercellular receptor-ligand binding and coalescence of nanoscale lipid clusters in adhering membranes. Soft Matter. PMID 33416062 DOI: 10.1039/d0sm01904f   
2021 Yang D, Zhou Q, Labroska V, Qin S, Darbalaei S, Wu Y, Yuliantie E, Xie L, Tao H, Cheng J, Liu Q, Zhao S, Shui W, Jiang Y, Wang MW. G protein-coupled receptors: structure- and function-based drug discovery. Signal Transduction and Targeted Therapy. 6: 7. PMID 33414387 DOI: 10.1038/s41392-020-00435-w   
2021 Yunn NO, Park M, Park S, Lee J, Noh J, Shin E, Ryu SH. A hotspot for enhancing insulin receptor activation revealed by a conformation-specific allosteric aptamer. Nucleic Acids Research. PMID 33410883 DOI: 10.1093/nar/gkaa1247   
2021 Lozano-Juste J, García-Maquilón I, Brea J, Piña R, Albert A, Rodriguez PL, Loza MI. Identification of ABA Receptor Agonists Using a Multiplexed High-Throughput Chemical Screening. Methods in Molecular Biology (Clifton, N.J.). 2213: 99-111. PMID 33270196 DOI: 10.1007/978-1-0716-0954-5_9   
2021 Zhang Y, Li S, Zhang H, Xu H. Design and Application of Receptor-Targeted Fluorescent Probes Based on Small Molecular Fluorescent Dyes. Bioconjugate Chemistry. PMID 33412857 DOI: 10.1021/acs.bioconjchem.0c00606   
2021 Hamilton LJ, Walker M, Pattabiraman M, Zhong HA, Luedtke B, Chandra S. Novel curcumin analog (Cis-Trans Curcumin) as ligand to adenosine receptors A and A: potential for therapeutics. Pharmacological Research. 105410. PMID 33401004 DOI: 10.1016/j.phrs.2020.105410   
2021 Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Janowska K, Gobeil SMC, Kopp M, Li D, Lu X, Mu Z, Deyton M, Oguin TH, Sprenz J, et al. Cold sensitivity of the SARS-CoV-2 spike ectodomain. Nature Structural & Molecular Biology. PMID 33402708 DOI: 10.1038/s41594-020-00547-5