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David Y. Gin, Ph.D. - Publications

Affiliations: 
1996-2006 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2006-2011 Chemistry Memorial Sloan-Kettering, Hauppauge, NY, United States 
Area:
Organic Chemistry, Natural Product Synthesis, Medicinal Chemistry
Website:
https://www.mskcc.org/event/david-y-gin-symposium
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65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Karimov RR, Tan DS, Gin DY. Synthesis of the hexacyclic triterpene core of the jujuboside saponins via tandem Wolff rearrangement-intramolecular ketene hetero-Diels-Alder reaction. Tetrahedron. 74: 3370-3383. PMID 30467444 DOI: 10.1016/J.Tet.2018.04.051  0.816
2017 Karimov RR, Tan DS, Gin DY. Rapid assembly of the doubly-branched pentasaccharide domain of the immunoadjuvant jujuboside A via convergent B(C6F5)3-catalyzed glycosylation of sterically-hindered precursors. Chemical Communications (Cambridge, England). PMID 28498382 DOI: 10.1039/C7Cc01783A  0.797
2017 Fernández-Tejada A, Walkowicz WE, Tan DS, Gin DY. Semisynthesis of Analogues of the Saponin Immunoadjuvant QS-21. Methods in Molecular Biology (Clifton, N.J.). 1494: 45-71. PMID 27718185 DOI: 10.1007/978-1-4939-6445-1_4  0.574
2016 Fernández-Tejada A, Tan DS, Gin DY. Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis. Accounts of Chemical Research. PMID 27568877 DOI: 10.1021/Acs.Accounts.6B00242  0.583
2016 Walkowicz WE, Fernández-Tejada A, George C, Corzana F, Jiménez-Barbero J, Ragupathi G, Tan DS, Gin DY. Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities. Chemical Science (Royal Society of Chemistry : 2010). 7: 2371-2380. PMID 27014435 DOI: 10.1039/C5Sc02978C  0.558
2015 Fernández-Tejada A, Tan DS, Gin DY. Correction: Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants. Chemical Communications (Cambridge, England). 51: 14410. PMID 26334089 DOI: 10.1039/c5cc90397a  0.493
2015 Fernández-Tejada A, Tan DS, Gin DY. Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants. Chemical Communications (Cambridge, England). PMID 26243268 DOI: 10.1039/C5Cc05244K  0.6
2014 Fernández-Tejada A, Chea EK, George C, Gardner JR, Livingston PO, Ragupathi G, Tan DS, Gin DY. Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol. Bioorganic & Medicinal Chemistry. 22: 5917-23. PMID 25284254 DOI: 10.1016/J.Bmc.2014.09.016  0.553
2014 Pla D, Tan DS, Gin DY. 5-(Methylthio)tetrazoles as Versatile Synthons in the Stereoselective Synthesis of Polycyclic Pyrazolines via Photoinduced Intramolecular Nitrile Imine-Alkene 1,3-Dipolar Cycloaddition. Chemical Science (Royal Society of Chemistry : 2010). 5: 2407-2415. PMID 25114776 DOI: 10.1039/C4Sc00107A  0.773
2014 Fernández-Tejada A, Chea EK, George C, Pillarsetty N, Gardner JR, Livingston PO, Ragupathi G, Lewis JS, Tan DS, Gin DY. Development of a minimal saponin vaccine adjuvant based on QS-21. Nature Chemistry. 6: 635-43. PMID 24950335 DOI: 10.1038/Nchem.1963  0.544
2013 Shi Y, Wilmot JT, Nordstrøm LU, Tan DS, Gin DY. Total synthesis, relay synthesis, and structural confirmation of the C18-norditerpenoid alkaloid neofinaconitine. Journal of the American Chemical Society. 135: 14313-20. PMID 24040959 DOI: 10.1021/Ja4064958  0.817
2013 Peese KM, Gin DY. Nominine Total Synthesis of Natural Products: At the Frontiers of Organic Chemistry. 1-24. DOI: 10.1007/978-3-642-34065-9_1  0.712
2012 Chea EK, Fernández-Tejada A, Damani P, Adams MM, Gardner JR, Livingston PO, Ragupathi G, Gin DY. Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes. Journal of the American Chemical Society. 134: 13448-57. PMID 22866694 DOI: 10.1021/Ja305121Q  0.344
2011 Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, et al. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity. Nature. 472: 486-90. PMID 21441909 DOI: 10.1038/Nature09978  0.665
2010 Perl NR, Ide ND, Prajapati S, Perfect HH, Durón SG, Gin DY. Annulation of thioimidates and vinyl carbodiimides to prepare 2-aminopyrimidines, competent nucleophiles for intramolecular alkyne hydroamination. Synthesis of (-)-crambidine. Journal of the American Chemical Society. 132: 1802-3. PMID 20095555 DOI: 10.1021/Ja910831K  0.817
2010 Epperson MT, Gin DY. ChemInform Abstract: Enantiospecific Synthesis of the Bridged Pyrrolizidine Core of Asparagamine A: Dipolar Cycloadditions of Azomethine Ylides Derived from the Sulfonylation of Vinylogous Amides. Cheminform. 33: no-no. DOI: 10.1002/chin.200239207  0.804
2010 MYERS AG, GIN DY, ROGERS DH. ChemInform Abstract: Synthetic Studies of the Tunicamycin Antibiotics. Preparation of (+)- Tunicaminyluracil, (+)-Tunicamycin-V, and 5′-epi-Tunicamycin-V. Cheminform. 25: no-no. DOI: 10.1002/chin.199446258  0.585
2010 MYERS AG, GIN DY, ROGERS DH. ChemInform Abstract: A Convergent Synthetic Route to the Tunicamycin Antibiotics. Synthesis of (+)-Tunicamycin V. Cheminform. 24: no-no. DOI: 10.1002/chin.199330291  0.662
2010 MYERS AG, GIN DY, WIDDOWSON KL. ChemInform Abstract: Silicon-Mediated Reductive Coupling of Aldehydes and Allylic Alcohols. A Stereoselective Synthesis of Tunicaminyluracil. Cheminform. 23: no-no. DOI: 10.1002/chin.199215292  0.64
2008 Ryan DA, Gin DY. Ring-opening of aziridine-2-carboxamides with carbohydrate C1-O-nucleophiles. Stereoselective preparation of alpha- and beta-O-glycosyl serine conjugates. Journal of the American Chemical Society. 130: 15228-9. PMID 18950157 DOI: 10.1021/Ja804589J  0.358
2008 Bultman MS, Ma J, Gin DY. Synthetic access to the chlorocyclopentane cores of the proposed original and revised structures of palau'amine. Angewandte Chemie (International Ed. in English). 47: 6821-4. PMID 18655078 DOI: 10.1002/Anie.200801969  0.807
2008 Carra RJ, Epperson MT, Gin DY. Application of an intramolecular dipolar cycloaddition to an asymmetric synthesis of the fully oxygenated tricyclic core of the stemofoline alkaloids. Tetrahedron. 64: 3629-3641. PMID 18443655 DOI: 10.1016/J.Tet.2008.02.008  0.795
2008 Deng K, Adams MM, Gin DY. Synthesis and structure verification of the vaccine adjuvant QS-7-Api. Synthetic access to homogeneous Quillaja saponaria immunostimulants. Journal of the American Chemical Society. 130: 5860-1. PMID 18410100 DOI: 10.1021/Ja801008M  0.334
2008 Eckelbarger JD, Wilmot JT, Epperson MT, Thakur CS, Shum D, Antczak C, Tarassishin L, Djaballah H, Gin DY. Synthesis of antiproliferative Cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: uncovering differential susceptibilities to multidrug resistance. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 4293-306. PMID 18366032 DOI: 10.1002/Chem.200701998  0.735
2008 Peese KM, Gin DY. Asymmetric synthetic access to the hetisine alkaloids: total synthesis of (+)-nominine. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 1654-65. PMID 18046691 DOI: 10.1002/Chem.200701290  0.784
2008 Gin D, Deng K, Adams M. Synthesis of QS-7-Api Synfacts. 2008: 1125-1125. DOI: 10.1055/s-0028-1083419  0.396
2007 Gin D, Eckelbarger J, Wilmot J. Synthesis of (-)-Deoxyharringtonine Synfacts. 2007: 0002-0002. DOI: 10.1055/s-2006-955658  0.788
2006 Arnold MA, Day KA, Durón SG, Gin DY. Total synthesis of (+)-batzelladine A and (-)-batzelladine D via [4 + 2]-annulation of vinyl carbodiimides with N-alkyl imines. Journal of the American Chemical Society. 128: 13255-60. PMID 17017806 DOI: 10.1021/Ja063860+  0.812
2006 Kim YJ, Wang P, Navarro-Villalobos M, Rohde BD, Derryberry J, Gin DY. Synthetic studies of complex immunostimulants from Quillaja saponaria: synthesis of the potent clinical immunoadjuvant QS-21Aapi. Journal of the American Chemical Society. 128: 11906-15. PMID 16953631 DOI: 10.1021/Ja062364I  0.518
2006 Eckelbarger JD, Wilmot JT, Gin DY. Strain-release rearrangement of N-vinyl-2-arylaziridines. Total synthesis of the anti-leukemia alkaloid (-)-deoxyharringtonine. Journal of the American Chemical Society. 128: 10370-1. PMID 16895394 DOI: 10.1021/Ja063304F  0.781
2006 Peese KM, Gin DY. Efficient synthetic access to the hetisine C20-diterpenoid alkaloids. A concise synthesis of nominine via oxidoisoquinolinium-1,3-dipolar and dienamine-Diels-Alder cycloadditions. Journal of the American Chemical Society. 128: 8734-5. PMID 16819859 DOI: 10.1021/Ja0625430  0.815
2006 Gin D, Peese K. Synthesis of (±)-Nominine Synfacts. 2006: 1206-1206. DOI: 10.1055/S-2006-955599  0.724
2005 Bodine KD, Gin DY, Gin MS. Highly convergent synthesis of C3- or C2-symmetric carbohydrate macrocycles. Organic Letters. 7: 4479-82. PMID 16178563 DOI: 10.1021/Ol051818Y  0.787
2005 Boebel TA, Gin DY. Probing the mechanism of sulfoxide-catalyzed hemiacetal activation in dehydrative glycosylation. The Journal of Organic Chemistry. 70: 5818-26. PMID 16018673 DOI: 10.1021/Jo050294C  0.8
2005 Peese KM, Gin DY. Enantioselective approach to the hetisine alkaloids. Synthesis of the 3-methyl-1-aza-tricyclo[5.2.1.0(3,8)]decane core via intramolecular dipolar cycloaddition. Organic Letters. 7: 3323-5. PMID 16018651 DOI: 10.1021/Ol051184V  0.782
2005 Galoni? DP, Ide ND, van der Donk WA, Gin DY. Aziridine-2-carboxylic acid-containing peptides: application to solution- and solid-phase convergent site-selective peptide modification. Journal of the American Chemical Society. 127: 7359-69. PMID 15898784 DOI: 10.1021/Ja050304R  0.731
2005 Arnold MA, Durón SG, Gin DY. Diastereoselective [4+2] annulation of vinyl carbodiimides with N-alkyl imines. Asymmetric synthetic access to the batzelladine alkaloids. Journal of the American Chemical Society. 127: 6924-5. PMID 15884915 DOI: 10.1021/Ja0519029  0.813
2005 Wang P, Kim YJ, Navarro-Villalobos M, Rohde BD, Gin DY. Synthesis of the potent immunostimulatory adjuvant QS-21A. Journal of the American Chemical Society. 127: 3256-7. PMID 15755124 DOI: 10.1021/Ja0422007  0.495
2005 Ide ND, Galoni? DP, Van Der Donk WA, Gin DY. Conjugation of selenols with aziridine-2-carboxylic acid-containing peptides Synlett. 2011-2014. DOI: 10.1055/S-2005-871972  0.724
2004 Bodine KD, Gin DY, Gin MS. Synthesis of readily modifiable cyclodextrin analogues via cyclodimerization of an alkynyl-azido trisaccharide. Journal of the American Chemical Society. 126: 1638-9. PMID 14871087 DOI: 10.1021/Ja039374T  0.791
2003 Boebel TA, Gin DY. Sulfoxide covalent catalysis: application to glycosidic bond formation. Angewandte Chemie (International Ed. in English). 42: 5874-7. PMID 14673924 DOI: 10.1002/Anie.200352761  0.759
2003 Haberman JM, Gin DY. Dehydrative sialylation with C2-hemiketal sialyl donors. Organic Letters. 5: 2539-41. PMID 12841775 DOI: 10.1021/Ol034815Z  0.795
2002 Epperson MT, Gin DY. Enantiospecific synthesis of the bridged pyrrolizidine core of asparagamine A: dipolar cycloadditions of azomethine ylides derived from the sulfonylation of vinylogous amides. Angewandte Chemie (International Ed. in English). 41: 1778-80. PMID 19750714 DOI: 10.1002/1521-3773(20020517)41:10<1778::Aid-Anie1778>3.0.Co;2-R  0.807
2002 Liu J, Gin DY. C2-amidoglycosylation. Scope and mechanism of nitrogen transfer. Journal of the American Chemical Society. 124: 9789-97. PMID 12175238 DOI: 10.1021/Ja026281N  0.413
2002 Honda E, Gin DY. C2-hydroxyglycosylation with glycal donors. Probing the mechanism of sulfonium-mediated oxygen transfer to glycal enol ethers. Journal of the American Chemical Society. 124: 7343-52. PMID 12071743 DOI: 10.1021/Ja025639C  0.346
2001 Nguyen HM, Poole JL, Gin DY. Chemoselective Iterative Dehydrative Glycosylation. Angewandte Chemie (International Ed. in English). 40: 414-417. PMID 29712399 DOI: 10.1002/1521-3773(20010119)40:2<414::AID-ANIE414>3.0.CO;2-6  0.482
2001 Nguyen HM, Chen Y, Duron SG, Gin DY. Sulfide-mediated dehydrative glycosylation. Journal of the American Chemical Society. 123: 8766-72. PMID 11535081 DOI: 10.1021/Ja015968P  0.785
2001 Shi L, Kim YJ, Gin DY. C2-acyloxyglycosylation with glycal donors. Journal of the American Chemical Society. 123: 6939-40. PMID 11448206 DOI: 10.1021/Ja015991A  0.481
2001 Kim JY, Di Bussolo V, Gin DY. Stereoselective synthesis of 2-hydroxy-alpha-mannopyranosides from glucal donors. Organic Letters. 3: 303-6. PMID 11430060 DOI: 10.1021/Ol006941Y  0.367
2001 Kim YJ, Gin DY. Synthesis of the trisaccharide portion of the immunologic adjuvant QS-21A via sulfonium-mediated oxidative and dehydrative glycosylation. Organic Letters. 3: 1801-4. PMID 11405715 DOI: 10.1021/Ol015651U  0.557
2001 Haberman JM, Gin DY. A new C(1)-auxiliary for anomeric stereocontrol in the synthesis of alpha-sialyl glycosides. Organic Letters. 3: 1665-8. PMID 11405681 DOI: 10.1021/Ol015854I  0.79
2001 Duron SG, Gin DY. Synthesis and determination of absolute configuration of the bicyclic guanidine core of batzelladine A. Organic Letters. 3: 1551-4. PMID 11388864 DOI: 10.1021/Ol015848M  0.787
2001 Nguyen HM, Poole JL, Gin DY. Chemoselective Iterative Dehydrative Glycosylation This research was supported by the National Institutes of Health (Grant no.: GM-58833), the Arnold and Mabel Beckman Foundation (BYI), Glaxo Wellcome Inc., and the Alfred P. Sloan Foundation. D.Y.G. is a Cottrell Scholar of Research Corporation. Angewandte Chemie (International Ed. in English). 40: 414-417. PMID 11180342 DOI: 10.1002/1521-3773(20010119)40:2<414::AID-ANIE414>3.0.CO;2-6  0.361
2000 Garcia BA, Gin DY. Synthesis of glycosyl-1-phosphates via dehydrative glycosylation Organic Letters. 2: 3411. PMID 11029224  0.625
2000 Garcia BA, Gin DY. Synthesis of glycosyl-1-phosphates via dehydrative glycosylation. Organic Letters. 2: 2135-8. PMID 10891249 DOI: 10.1021/Ol006041H  0.606
2000 Di Bussolo V, Liu J, Huffman Jr, Gin DY. Acetamidoglycosylation with Glycal Donors: A One-Pot Glycosidic Coupling with Direct Installation of the Natural C(2)-N-Acetylamino Functionality. Angewandte Chemie (International Ed. in English). 39: 204-207. PMID 10649376 DOI: 10.1002/(Sici)1521-3773(20000103)39:1<204::Aid-Anie204>3.0.Co;2-Z  0.376
2000 Garcia BA, Gin DY. Dehydrative glycosylation with activated diphenyl sulfonium reagents. Scope, mode of C(1)-hemiacetal activation, and detection of reactive glycosyl intermediates Journal of the American Chemical Society. 122: 4269-4279. DOI: 10.1021/Ja993595A  0.617
1998 Di Bussolo V, Kim YJ, Gin DY. Direct oxidative glycosylations with glycal donors [2] Journal of the American Chemical Society. 120: 13515-13516. DOI: 10.1021/Ja982112K  0.377
1997 Garcia BA, Poole JL, Gin DY. Direct glycosylations with 1-hydroxy glycosyl donors using trifluoromethanesulfonic anhydride and diphenyl sulfoxide Journal of the American Chemical Society. 119: 7597-7598. DOI: 10.1021/Ja971067Y  0.516
1996 Corey EJ, Gin DY, Kania RS. Enantioselective total synthesis of ecteinascidin 743 Journal of the American Chemical Society. 118: 9202-9203. DOI: 10.1021/Ja962480T  0.654
1996 Corey EJ, Gin DY. A convergent enantioselective synthesis of the tetrahydroisoquinoline unit in the spiro ring of ecteinascidin 743 Tetrahedron Letters. 37: 7163-7166. DOI: 10.1016/0040-4039(96)01622-X  0.641
1994 Myers AG, Gin DY, Rogers DH. Synthetic Studies of the Tunicamycin Antibiotics. Preparation of (+)-Tunicaminyluracil, (+)-Tunicamycin-V, and 5'-epi-Tunicamycin-V Journal of the American Chemical Society. 116: 4697-4718. DOI: 10.1021/Ja00090A018  0.568
1993 Myers AG, Gin DY, Rogers DH. A convergent synthetic route to the tunicamycin antibiotics. Synthesis of (+)-tunicamycin V Journal of the American Chemical Society. 115: 2036-2038. DOI: 10.1021/Ja00058A060  0.699
1991 Myers AG, Gin DY, Widdowson KL. Silicon-mediated reductive coupling of aldehydes and allylic alcohols. A stereoselective synthesis of tunicaminyluracil Journal of the American Chemical Society. 113: 9661-9663. DOI: 10.1021/Ja00025A036  0.635
1990 Gin DY, Cader MSR, Sams JR, Aubke F. 1,3,5-Trimethylbenzene(mesitylene) adducts with selected tin(II) compounds: the syntheses of Sn(SO3F)2•C9H12 and Sn(SbF6)2•2C9H12 Canadian Journal of Chemistry. 68: 350-355. DOI: 10.1139/v90-051  0.495
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