Jean-Sébastien Rougier - Publications

Affiliations: 
2002-2006 Pharmacology and Toxicology University of Lausanne, Lausanne, Vaud, Switzerland 

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Iamshanova O, Hämmerli AF, Ramaye E, Seljmani A, Ross-Kaschitza D, Schärz N, Essers M, Guichard S, Rougier JS, Abriel H. The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5. Plos One. 19: e0298820. PMID 38452156 DOI: 10.1371/journal.pone.0298820  0.499
2023 Arullampalam P, Essers MC, Boukenna M, Guichard S, Rougier JS, Abriel H. Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex- and age-dependent manner in mice. Physiological Reports. 11: e15783. PMID 37604672 DOI: 10.14814/phy2.15783  0.645
2023 Selimi Z, Rougier JS, Abriel H, Kucera JP. A detailed analysis of single-channel Na 1.5 recordings does not reveal any cooperative gating. The Journal of Physiology. 601: 3847-3868. PMID 37470338 DOI: 10.1113/JP284861  0.708
2023 Boukenna M, Rougier JS, Aghagolzadeh P, Pradervand S, Guichard S, Hämmerli AF, Pedrazzini T, Abriel H. Multiomics uncover the proinflammatory role of deletion after myocardial infarction in mice. American Journal of Physiology. Heart and Circulatory Physiology. 324: H504-H518. PMID 36800508 DOI: 10.1152/ajpheart.00671.2022  0.588
2022 Preti B, Rougier JS, Papapostolou I, Bochen F, Gerber CE, Abriel H, Lochner M, Peinelt C. Targeting Ion Channel TRPM4. Chimia. 76: 1039-1044. PMID 38069800 DOI: 10.2533/chimia.2022.1039  0.656
2021 Amarouch MY, Zaklyazminskaya EV, Rougier JS. Editorial: Inherited Arrhythmias of the Cardiac Sodium Channel Na1.5. Frontiers in Physiology. 12: 716553. PMID 34421659 DOI: 10.3389/fphys.2021.716553  0.521
2021 Arullampalam P, Preti B, Ross-Kaschitza D, Lochner M, Rougier JS, Abriel H. Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors. Frontiers in Pharmacology. 12: 712354. PMID 34335274 DOI: 10.3389/fphar.2021.712354  0.665
2021 Ozhathil LC, Rougier JS, Arullampalam P, Essers MC, Ross-Kaschitza D, Abriel H. Deletion of Alters the Function of the Na1.5 Channel in Murine Cardiac Myocytes. International Journal of Molecular Sciences. 22. PMID 33810249 DOI: 10.3390/ijms22073401  0.73
2020 Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier JS, Abriel H. Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na1.5. Channels (Austin, Tex.). 14: 268-286. PMID 32815768 DOI: 10.1080/19336950.2020.1805999  0.825
2020 Vermij SH, Rougier JS, Agulló-Pascual E, Rothenberg E, Delmar M, Abriel H. Single-molecule Localization of Na1.5 Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circulation. Arrhythmia and Electrophysiology. PMID 32536203 DOI: 10.1161/Circep.119.008241  0.822
2019 Gillet L, Guichard S, Essers MC, Rougier JS, Abriel H. Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Scientific Reports. 9: 19422. PMID 31857666 DOI: 10.1038/S41598-019-55950-W  0.795
2019 Casini S, Albesa M, Wang Z, Portero V, Ross-Kaschitza D, Rougier JS, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA. Functional Consequences of the -p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice. International Journal of Molecular Sciences. 20. PMID 31614475 DOI: 10.3390/Ijms20205033  0.826
2019 Neubauer J, Wang Z, Rougier JS, Abriel H, Rieubland C, Bartholdi D, Haas C, Medeiros-Domingo A. Functional characterization of a novel SCN5A variant associated with long QT syndrome and sudden cardiac death. International Journal of Legal Medicine. PMID 31455979 DOI: 10.1007/S00414-019-02141-X  0.834
2019 Rougier JS, Essers MC, Gillet L, Guichard S, Sonntag S, Shmerling D, Abriel H. A Distinct Pool of Na1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Frontiers in Physiology. 10: 834. PMID 31333492 DOI: 10.3389/Fphys.2019.00834  0.818
2018 Blancard M, Debbiche A, Kato K, Cardin C, Sabrina G, Gandjbakhch E, Probst V, Haissaguerre M, Extramiana F, Hocini M, Olivier G, Leenhardt A, Guicheney P, Rougier JS. An African loss-of-function CACNA1C variant p.T1787M associated with a risk of ventricular fibrillation. Scientific Reports. 8: 14619. PMID 30279520 DOI: 10.1038/S41598-018-32867-4  0.479
2018 Tamo L, Hibaoui Y, Kallol S, Alves MP, Albrecht C, Hostettler KE, Feki A, Rougier JS, Abriel H, Knudsen L, Gazdhar A, Geiser T. Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30211653 DOI: 10.1152/Ajplung.00357.2017  0.556
2018 Neubauer J, Rougier JS, Abriel H, Haas C. Functional implications of a rare variant in the sodium channel β1B subunit () in a 5-month-old male sudden infant death syndrome case. Heartrhythm Case Reports. 4: 187-190. PMID 29915715 DOI: 10.1016/J.Hrcr.2018.01.010  0.603
2018 Casini S, Portero V, Rougier JS, Albesa M, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA. P265Functional characterization of a LQT3 mutation located in the PY motif of the cardiac sodium channel associated with altered channel ubiquitylation Cardiovascular Research. 114: S68-S68. DOI: 10.1093/Cvr/Cvy060.185  0.853
2017 Hinard V, Britan A, Schaeffer M, Zahn-Zabal M, Thomet U, Rougier JS, Bairoch A, Abriel H, Gaudet P. Annotation of functional impact of voltage-gated sodium channel mutations. Human Mutation. PMID 28168870 DOI: 10.1002/Humu.23191  0.729
2016 Nafzger S, Rougier JS. Calcium/calmodulin-dependent serine protein kinase CASK modulates the L-type calcium current. Cell Calcium. PMID 27720444 DOI: 10.1016/J.Ceca.2016.10.001  0.5
2016 Eichel CA, Beuriot A, Chevalier MY, Rougier JS, Louault F, Dilanian G, Amour J, Coulombe A, Abriel H, Hatem SN, Balse E. Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circulation Research. 119: 544-56. PMID 27364017 DOI: 10.1161/Circresaha.116.309254  0.816
2016 Syam N, Chatel S, Ozhathil LC, Sottas V, Rougier JS, Baruteau A, Baron E, Amarouch MY, Daumy X, Probst V, Schott JJ, Abriel H. Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block. Journal of the American Heart Association. 5. PMID 27207958 DOI: 10.1161/Jaha.114.001625  0.798
2016 Hinard V, Britan A, Rougier JS, Bairoch A, Abriel H, Gaudet P. ICEPO: the ion channel electrophysiology ontology. Database : the Journal of Biological Databases and Curation. 2016. PMID 27055825 DOI: 10.1093/Database/Baw017  0.681
2016 Rougier JS, Abriel H. Cardiac voltage-gated calcium channel macromolecular complexes. Biochimica Et Biophysica Acta. 1863: 1806-12. PMID 26707467 DOI: 10.1016/J.Bbamcr.2015.12.014  0.743
2015 Abriel H, Rougier JS, Jalife J. Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death. Circulation Research. 116: 1971-88. PMID 26044251 DOI: 10.1161/Circresaha.116.305017  0.684
2015 Gillet L, Rougier JS, Shy D, Sonntag S, Mougenot N, Essers M, Shmerling D, Balse E, Hatem SN, Abriel H. Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 12: 181-92. PMID 25447080 DOI: 10.1016/J.Hrthm.2014.09.057  0.835
2015 Rougier JS, Albesa M, Syam N, Halet G, Abriel H, Viard P. Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels. Pflugers Archiv : European Journal of Physiology. 467: 1919-29. PMID 25366495 DOI: 10.1007/S00424-014-1636-6  0.825
2015 Rougier J, Abriel H. 0151 : Role a calcium/calmodulin-dependent serine protein kinase on Cav1.2 channel regulation Archives of Cardiovascular Diseases Supplements. 7: 167-168. DOI: 10.1016/S1878-6480(15)30101-4  0.722
2014 Shy D, Gillet L, Ogrodnik J, Albesa M, Verkerk AO, Wolswinkel R, Rougier JS, Barc J, Essers MC, Syam N, Marsman RF, van Mil AM, Rotman S, Redon R, Bezzina CR, et al. PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function. Circulation. 130: 147-60. PMID 24895455 DOI: 10.1161/Circulationaha.113.007852  0.803
2014 Syam N, Rougier JS, Abriel H. Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects. Frontiers in Cellular Neuroscience. 8: 52. PMID 24605085 DOI: 10.3389/Fncel.2014.00052  0.852
2014 Gillet L, Shy D, Sonntag S, Rougier J, Verkerk A, Essers M, Marsman R, Shmerling D, Bezzina C, Remme CA, Abriel H. 0150: PDZ domain proteins interacting with Nav1.5 differentially regulate Nav1.5 channel pools in mouse cardiomyocytes Archives of Cardiovascular Diseases Supplements. 6: 40-41. DOI: 10.1016/S1878-6480(14)71373-4  0.854
2014 Syam N, Chatel S, Rougier J, Sottas V, Baruteau A, Probst V, Schott J, Abriel H. TRPM4 Genetic Variants in Patients with Congenital Atrio-Ventricular Block Biophysical Journal. 106: 762a. DOI: 10.1016/J.Bpj.2013.11.4192  0.796
2013 Reinhard K, Rougier JS, Ogrodnik J, Abriel H. Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na v1.5 expressed in HEK293 cells. F1000research. 2: 48. PMID 24555036 DOI: 10.12688/F1000Research.2-48.V2  0.827
2013 Abriel H, Rougier JS. β-blockers in congenital short-QT syndrome as ion channel blockers. Journal of Cardiovascular Electrophysiology. 24: 1172-4. PMID 23890274 DOI: 10.1111/Jce.12204  0.646
2013 Sottas V, Rougier JS, Jousset F, Kucera JP, Shestak A, Makarov LM, Zaklyazminskaya EV, Abriel H. Characterization of 2 genetic variants of Na(v) 1.5-arginine 689 found in patients with cardiac arrhythmias. Journal of Cardiovascular Electrophysiology. 24: 1037-46. PMID 23692053 DOI: 10.1111/Jce.12173  0.841
2013 Rougier JS, Gavillet B, Abriel H. Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice. Frontiers in Physiology. 4: 51. PMID 23532763 DOI: 10.3389/Fphys.2013.00051  0.841
2012 Rougier JS, Abriel H. Role of "non-cardiac" voltage-gated sodium channels in cardiac cells. Journal of Molecular and Cellular Cardiology. 53: 589-90. PMID 22967322 DOI: 10.1016/J.Yjmcc.2012.08.011  0.727
2012 Rougier JS, Abriel H. Unexpected dominance: Brugada syndrome SCN5A variants exert negative dominance via α-subunit interaction. Cardiovascular Research. 96: 1-3. PMID 22871588 DOI: 10.1093/Cvr/Cvs264  0.698
2012 Abriel H, Syam N, Sottas V, Amarouch MY, Rougier JS. TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology. Biochemical Pharmacology. 84: 873-81. PMID 22750058 DOI: 10.1016/J.Bcp.2012.06.021  0.812
2011 Templin C, Ghadri JR, Rougier JS, Baumer A, Kaplan V, Albesa M, Sticht H, Rauch A, Puleo C, Hu D, Barajas-Martinez H, Antzelevitch C, Lüscher TF, Abriel H, Duru F. Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6). European Heart Journal. 32: 1077-88. PMID 21383000 DOI: 10.1093/Eurheartj/Ehr076  0.835
2011 Rougier JS, Albesa M, Abriel H, Viard P. Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels. The Journal of Biological Chemistry. 286: 8829-38. PMID 21220429 DOI: 10.1074/Jbc.M110.166520  0.821
2011 Albesa M, Ogrodnik J, Rougier JS, Abriel H. Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice. Cardiovascular Research. 89: 320-8. PMID 20952415 DOI: 10.1016/J.Hrthm.2010.09.031  0.829
2010 Pignier C, Rougier JS, Vié B, Culié C, Verscheure Y, Vacher B, Abriel H, Le Grand B. Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias. British Journal of Pharmacology. 161: 79-91. PMID 20718741 DOI: 10.1111/J.1476-5381.2010.00884.X  0.633
2010 Rougier JS, Albesa M, Abriel H. Ubiquitylation and SUMOylation of cardiac ion channels. Journal of Cardiovascular Pharmacology. 56: 22-8. PMID 20224423 DOI: 10.1097/Fjc.0B013E3181Daaff9  0.835
2010 Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge WH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, et al. Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. Plos One. 5: e9298. PMID 20174578 DOI: 10.1371/Journal.Pone.0009298  0.832
2008 Rougier JS, Muller O, Berger S, Centeno G, Schütz G, Firsov D, Abriel H. Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes. Pflã¼Gers Archiv : European Journal of Physiology. 456: 407-12. PMID 18040710 DOI: 10.1007/S00424-007-0387-Z  0.592
2007 Kranjcec D, Bergovec M, Rougier JS, Raguz M, Pavlovic S, Jespersen T, Castella V, Keller DI, Abriel H. Brugada syndrome unmasked by accidental inhalation of gasoline vapors. Pacing and Clinical Electrophysiology : Pace. 30: 1294-8. PMID 17897138 DOI: 10.1111/J.1540-8159.2007.00857.X  0.653
2006 Gavillet B, Rougier JS, Domenighetti AA, Behar R, Boixel C, Ruchat P, Lehr HA, Pedrazzini T, Abriel H. Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin Circulation Research. 99: 407-414. PMID 16857961 DOI: 10.1161/01.Res.0000237466.13252.5E  0.839
2006 Fodstad H, Bendahhou S, Rougier JS, Laitinen-Forsblom PJ, Barhanin J, Abriel H, Schild L, Kontula K, Swan H. Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients. Annals of Medicine. 38: 294-304. PMID 16754261 DOI: 10.1080/07853890600756065  0.592
2006 Camacho JA, Hensellek S, Rougier JS, Blechschmidt S, Abriel H, Benndorf K, Zimmer T. Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region. The Journal of Biological Chemistry. 281: 9498-506. PMID 16469732 DOI: 10.1074/Jbc.M509716200  0.718
2006 Boixel C, Gavillet B, Rougier JS, Abriel H. Aldosterone increases voltage-gated sodium current in ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2257-66. PMID 16428353 DOI: 10.1152/Ajpheart.01060.2005  0.842
2005 Keller DI, Rougier JS, Kucera JP, Benammar N, Fressart V, Guicheney P, Madle A, Fromer M, Schläpfer J, Abriel H. Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations. Cardiovascular Research. 67: 510-9. PMID 15890323 DOI: 10.1016/J.Cardiores.2005.03.024  0.684
2005 Rougier JS, van Bemmelen MX, Bruce MC, Jespersen T, Gavillet B, Apothéloz F, Cordonier S, Staub O, Rotin D, Abriel H. Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins. American Journal of Physiology. Cell Physiology. 288: C692-701. PMID 15548568 DOI: 10.1152/Ajpcell.00460.2004  0.833
2004 van Bemmelen MX, Rougier JS, Gavillet B, Apothéloz F, Daidié D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H. Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination. Circulation Research. 95: 284-91. PMID 15217910 DOI: 10.1161/01.Res.0000136816.05109.89  0.85
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