| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2024 | Burrows K, Heiskala A, Bradfield JP, Balkhiyarova Z, Ning L, Boissel M, Chan YM, Froguel P, Bonnefond A, Hakonarson H, Alves AC, Lawlor DA, Kaakinen M, Järvelin MR, Grant SFA, et al. A framework for conducting time-varying genome-wide association studies: An application to body mass index across childhood in six multiethnic cohorts. Medrxiv : the Preprint Server For Health Sciences. PMID 38559031 DOI: 10.1101/2024.03.13.24304263 | 0.4 | |||
| 2024 | Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Melloni GEM, Kanoni S, Rayner NW, Bocher O, Arruda AL, Sonehara K, Namba S, ... ... Bonnefond A, et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. PMID 38374256 DOI: 10.1038/s41586-024-07019-6 | 0.461 | |||
| 2024 | Folon L, Baron M, Scherrer V, Toussaint B, Vaillant E, Loiselle H, Dechaume A, De Pooter F, Boutry R, Boissel M, Diallo A, Ning L, Balkau B, Charpentier G, Franc S, ... ... Bonnefond A, et al. Pathogenic, Total Loss-of-Function DYRK1B Variants Cause Monogenic Obesity Associated With Type 2 Diabetes. Diabetes Care. PMID 38170957 DOI: 10.2337/dc23-1851 | 0.49 | |||
| 2023 | Dance A, Fernandes J, Toussaint B, Vaillant E, Boutry R, Baron M, Loiselle H, Balkau B, Charpentier G, Franc S, Ibberson M, Marre M, Gernay M, Fadeur M, Paquot N, ... ... Bonnefond A, et al. Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics. Molecular Metabolism. 101867. PMID 38159881 DOI: 10.1016/j.molmet.2023.101867 | 0.429 | |||
| 2023 | Kouidrat Y, Collen LL, Vaxillaire M, Dechaume A, Toussaint B, Vaillant E, Amanzougarene S, Derhourhi M, Delemer B, Azahaf M, Froguel P, Bonnefond A. Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: lessons for precision medicine. Diabetes & Metabolism. 101507. PMID 38141807 DOI: 10.1016/j.diabet.2023.101507 | 0.467 | |||
| 2023 | Johanns M, Haas JT, Raverdy V, Vandel J, Chevalier-Dubois J, Guille L, Derudas B, Legendre B, Caiazzo R, Verkindt H, Gnemmi V, Leteurtre E, Derhourhi M, Bonnefond A, Froguel P, et al. Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD. Jhep Reports : Innovation in Hepatology. 6: 100948. PMID 38125300 DOI: 10.1016/j.jhepr.2023.100948 | 0.304 | |||
| 2023 | Meulebrouck S, Scherrer V, Boutry R, Toussaint B, Vaillant E, Dechaume A, Loiselle H, Balkau B, Charpentier G, Franc S, Marre M, Baron M, Vaxillaire M, Derhourhi M, Boissel M, ... ... Bonnefond A, et al. Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas. Diabetologia. PMID 38051360 DOI: 10.1007/s00125-023-06035-x | 0.495 | |||
| 2023 | de Las Fuentes L, Schwander KL, Brown MR, Bentley AR, Winkler TW, Sung YJ, Munroe PB, Miller CL, Aschard H, Aslibekyan S, Bartz TM, Bielak LF, Chai JF, Cheng CY, Dorajoo R, ... ... Bonnefond A, et al. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci. Frontiers in Genetics. 14: 1235337. PMID 38028628 DOI: 10.3389/fgene.2023.1235337 | 0.365 | |||
| 2023 | Fumeron F, Velho G, Alzaid F, El Boustany R, Vandiedonck C, Bonnefond A, Froguel P, Potier L, Marre M, Balkau B, Roussel R, Venteclef N. Genetic variants of interferon-response factor 5 are associated with the incidence of chronic kidney disease: the D.E.S.I.R. study. Genes and Immunity. 24: 303-308. PMID 37978231 DOI: 10.1038/s41435-023-00229-4 | 0.335 | |||
| 2023 | Gao W, Liu L, Huh E, Gbahou F, Cecon E, Oshima M, Houzé L, Katsonis P, Hegron A, Fan Z, Hou G, Charpentier G, Boissel M, Derhourhi M, Marre M, ... ... Bonnefond A, et al. Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity. Nature Metabolism. PMID 37709961 DOI: 10.1038/s42255-023-00889-6 | 0.477 | |||
| 2023 | Saeed S, Khanam R, Janjua QM, Manzoor J, Ning L, Hanook S, Canouil M, Ali M, Ayesha H, Khan WI, Farooqi IS, Yeo GSH, O'Rahilly S, Bonnefond A, Butt TA, et al. High morbidity and mortality in children with untreated congenital deficiency of leptin or its receptor. Cell Reports. Medicine. 101187. PMID 37659411 DOI: 10.1016/j.xcrm.2023.101187 | 0.336 | |||
| 2023 | Orioli L, Canouil M, Sawadogo K, Ning L, Deldicque L, Lause P, de Barsy M, Froguel P, Loumaye A, Deswysen Y, Navez B, Bonnefond A, Thissen JP. Identification of myokines susceptible to improve glucose homeostasis after bariatric surgery. European Journal of Endocrinology. 189: 409-421. PMID 37638789 DOI: 10.1093/ejendo/lvad122 | 0.379 | |||
| 2023 | Hu M, Bonas-Guarch S, Kim I, Morán I, Peng W, Bonnefond A, Khamis A, Froguel P, Rutter GA. Multiple genetic variants at the locus affect a local super-enhancer cluster to influence pancreatic β-cell survival and function. Biorxiv : the Preprint Server For Biology. PMID 37502937 DOI: 10.1101/2023.07.13.548906 | 0.445 | |||
| 2023 | Oger F, Moreno M, Derhourhi M, Thiroux B, Berberian L, Bourouh C, Durand E, Amanzougarene S, Badreddine A, Blanc E, Molendi-Coste O, Pineau L, Pasquetti G, Rolland L, Carney C, ... ... Bonnefond A, et al. Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming. Iscience. 26: 107231. PMID 37496675 DOI: 10.1016/j.isci.2023.107231 | 0.349 | |||
| 2023 | Maina JG, Balkhiyarova Z, Nouwen A, Pupko I, Ulrich A, Boissel M, Bonnefond A, Froguel P, Khamis A, Prokopenko I, Kaakinen M. Bidirectional Mendelian Randomization and Multiphenotype GWAS Show Causality and Shared Pathophysiology Between Depression and Type 2 Diabetes. Diabetes Care. PMID 37494602 DOI: 10.2337/dc22-2373 | 0.414 | |||
| 2023 | Oger F, Bourouh C, Friano ME, Courty E, Rolland L, Gromada X, Moreno M, Carney C, Rabhi N, Durand E, Amanzougarene S, Berberian L, Derhourhi M, Blanc E, Hannou SA, ... ... Bonnefond A, et al. β-cell specific E2f1 deficiency impairs glucose homeostasis, β-cell identity and insulin secretion. Diabetes. PMID 37216637 DOI: 10.2337/db22-0604 | 0.365 | |||
| 2023 | Maina JG, Pascat V, Zudina L, Ulrich A, Pupko I, Bonnefond A, Balkhiyarova Z, Kaakinen M, Froguel P, Prokopenko I. Abdominal obesity is a more important causal risk factor for pancreatic cancer than overall obesity. European Journal of Human Genetics : Ejhg. PMID 37161092 DOI: 10.1038/s41431-023-01301-3 | 0.397 | |||
| 2023 | Le Collen L, Delemer B, Poitou C, Vaxillaire M, Toussaint B, Dechaume A, Badreddine A, Boissel M, Derhourhi M, Clément K, Petit JM, Mau-Them FT, Bruel AL, Thauvin-Robinet C, Saveanu A, ... ... Bonnefond A, et al. Heterozygous pathogenic variants in POMC are not responsible for monogenic obesity: implication for MC4R agonist use. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 100857. PMID 37092539 DOI: 10.1016/j.gim.2023.100857 | 0.421 | |||
| 2023 | Saeed S, Ning L, Badreddine A, Mirza MU, Boissel M, Khanam R, Manzoor J, Janjua QM, Khan WI, Toussaint B, Vaillant E, Amanzougarene S, Derhourhi M, Trant JF, Siegert AM, ... ... Bonnefond A, et al. Biallelic mutations in P4HTM cause syndromic obesity. Diabetes. PMID 37083980 DOI: 10.2337/db22-1017 | 0.437 | |||
| 2023 | Xiao J, El Eid L, Buenaventura T, Boutry R, Bonnefond A, Jones B, Rutter GA, Froguel P, Tomas A. Control of human pancreatic beta cell kinome by GLP-1R biased agonism. Diabetes, Obesity & Metabolism. PMID 37039251 DOI: 10.1111/dom.15083 | 0.312 | |||
| 2023 | Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Rayner NW, Bocher O, Ana Luiza de SVA, Sonehara K, Namba S, Lee SSK, Preuss MH, ... ... Bonnefond A, et al. Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. Medrxiv : the Preprint Server For Health Sciences. PMID 37034649 DOI: 10.1101/2023.03.31.23287839 | 0.469 | |||
| 2023 | Kahoul Y, Yao X, Oger F, Moreno M, Amanzougarene S, Derhourhi M, Durand E, Boutry R, Bonnefond A, Froguel P, Dani C, Annicotte JS, Breton C. Knocking Down in 3D hiPSC-Derived Brown Adipose Progenitors Potentiates Differentiation, Oxidative Metabolism and Browning Process. Cells. 12. PMID 36980212 DOI: 10.3390/cells12060870 | 0.348 | |||
| 2023 | Talbot F, Feetham CH, Mokrosiński J, Lawler K, Keogh JM, Henning E, Mendes de Oliveira E, Ayinampudi V, Saeed S, Bonnefond A, Arslan M, Yeo GSH, Froguel P, Bechtold DA, Adamson A, et al. A rare human variant that disrupts GPR10 signalling causes weight gain in mice. Nature Communications. 14: 1450. PMID 36922513 DOI: 10.1038/s41467-023-36966-3 | 0.392 | |||
| 2023 | Bonnefond A, Unnikrishnan R, Doria A, Vaxillaire M, Kulkarni RN, Mohan V, Trischitta V, Froguel P. Monogenic diabetes. Nature Reviews. Disease Primers. 9: 12. PMID 36894549 DOI: 10.1038/s41572-023-00421-w | 0.475 | |||
| 2023 | Folon L, Baron M, Toussaint B, Vaillant E, Boissel M, Scherrer V, Loiselle H, Leloire A, Badreddine A, Balkau B, Charpentier G, Franc S, Marre M, Aboulouard S, Salzet M, ... ... Bonnefond A, et al. Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study. The Lancet. Diabetes & Endocrinology. 11: 182-190. PMID 36822744 DOI: 10.1016/S2213-8587(22)00392-8 | 0.459 | |||
| 2022 | Froguel P, Bonnefond A. The discovery of human agouti-induced obesity and its implication for genetic diagnosis. Nature Metabolism. 4: 1614-1615. PMID 36536131 DOI: 10.1038/s42255-022-00695-6 | 0.411 | |||
| 2022 | Bourouh C, Courty E, Rolland L, Pasquetti G, Gromada X, Rabhi N, Carney C, Moreno M, Boutry R, Caron E, Benfodda Z, Meffre P, Kerr-Conte J, Pattou F, Froguel P, ... Bonnefond A, et al. The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells. Cell Reports. 40: 111170. PMID 35947949 DOI: 10.1016/j.celrep.2022.111170 | 0.389 | |||
| 2022 | Pelletier A, Carrier A, Zhao Y, Canouil M, Derhourhi M, Durand E, Berberian-Ferrato L, Greally J, Hughes F, Froguel P, Bonnefond A, Delahaye F. Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates. International Journal of Molecular Sciences. 23. PMID 35806330 DOI: 10.3390/ijms23137323 | 0.331 | |||
| 2022 | Bonnefond A, Semple RK. Achievements, prospects and challenges in precision care for monogenic insulin-deficient and insulin-resistant diabetes. Diabetologia. PMID 35618782 DOI: 10.1007/s00125-022-05720-7 | 0.319 | |||
| 2022 | Khamis A, Ning L, Balkau B, Bonnefond A, Canouil M, Roussel R, Froguel P. Epigenetic changes associated with hyperglycaemia exposure in the longitudinal D.E.S.I.R. cohort. Diabetes & Metabolism. 48: 101347. PMID 35427775 DOI: 10.1016/j.diabet.2022.101347 | 0.364 | |||
| 2022 | Le Collen L, Delemer B, Spodenkiewicz M, Cornillet Lefebvre P, Durand E, Vaillant E, Badreddine A, Derhourhi M, Mouhoub TA, Jouret G, Juttet P, Souchon PF, Vaxillaire M, Froguel P, Bonnefond A, et al. Compound genetic etiology in a patient with a syndrome including diabetes, intellectual deficiency and distichiasis. Orphanet Journal of Rare Diseases. 17: 86. PMID 35227307 DOI: 10.1186/s13023-022-02248-2 | 0.469 | |||
| 2022 | Pervjakova N, Moen GH, Borges MC, Ferreira T, Cook JP, Allard C, Beaumont RN, Canouil M, Hatem G, Heiskala A, Joensuu A, Karhunen V, Kwak SH, Lin FTJ, Liu J, ... ... Bonnefond A, et al. Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes. Human Molecular Genetics. PMID 35220425 DOI: 10.1093/hmg/ddac050 | 0.473 | |||
| 2022 | Cornière N, Thomson RB, Thauvin S, Villoutreix BO, Karp S, Dynia DW, Burlein S, Brinkmann L, Badreddine A, Dechaume A, Derhourhi M, Durand E, Vaillant E, Froguel P, Chambrey R, ... ... Bonnefond A, et al. Dominant negative mutation in oxalate transporter associated with enteric hyperoxaluria and nephrolithiasis. Journal of Medical Genetics. PMID 35115415 DOI: 10.1136/jmedgenet-2021-108256 | 0.379 | |||
| 2022 | Wesolowska-Andersen A, Brorsson CA, Bizzotto R, Mari A, Tura A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Prehn C, Artati A, Hong MG, Musholt PB, ... ... Bonnefond A, et al. Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study. Cell Reports. Medicine. 3: 100477. PMID 35106505 DOI: 10.1016/j.xcrm.2021.100477 | 0.463 | |||
| 2022 | Tobi EW, Juvinao-Quintero DL, Ronkainen J, Ott R, Alfano R, Canouil M, Geurtsen ML, Khamis A, Küpers LK, Lim IY, Perron P, Pesce G, Tuhkanen J, Starling AP, Andrew T, ... ... Bonnefond A, et al. Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies. Diabetes Care. PMID 35104326 DOI: 10.2337/dc21-1701 | 0.314 | |||
| 2022 | Saeed S, Janjua QM, Haseeb A, Khanam R, Durand E, Vaillant E, Ning L, Badreddine A, Berberian L, Boissel M, Amanzougarene S, Canouil M, Derhourhi M, Bonnefond A, Arslan M, et al. Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan. Diabetes. PMID 35061034 DOI: 10.2337/db21-0373 | 0.467 | |||
| 2022 | Bornaque F, Delannoy CP, Courty E, Rabhi N, Carney C, Rolland L, Moreno M, Gromada X, Bourouh C, Petit P, Durand E, Pattou F, Kerr-Conte J, Froguel P, Bonnefond A, et al. Glucose Regulates mA Methylation of RNA in Pancreatic Islets. Cells. 11. PMID 35053407 DOI: 10.3390/cells11020291 | 0.422 | |||
| 2021 | Jungtrakoon Thamtarana P, Marucci A, Pannone L, Bonnefond A, Pezzilli S, Biagini T, Buranasupkajorn P, Hastings T, Mendonca C, Marselli L, Di Paola R, Abubakar Z, Mercuri L, Alberico F, Flex E, et al. Gain of function of Malate Dehydrogenase 2 (MDH2) and familial hyperglycemia. The Journal of Clinical Endocrinology and Metabolism. PMID 34718610 DOI: 10.1210/clinem/dgab790 | 0.471 | |||
| 2021 | Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, et al. Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. Acs Pharmacology & Translational Science. 4: 1614-1627. PMID 34661078 DOI: 10.1021/acsptsci.1c00157 | 0.36 | |||
| 2021 | Canouil M, Khamis A, Keikkala E, Hummel S, Lobbens S, Bonnefond A, Delahaye F, Tzala E, Mustaniemi S, Vääräsmäki M, Jarvelin MR, Sebert S, Kajantie E, Froguel P, Andrew T. Epigenome-Wide Association Study Reveals Methylation Loci Associated With Offspring Gestational Diabetes Mellitus Exposure and Maternal Methylome. Diabetes Care. PMID 34116986 DOI: 10.2337/dc20-2960 | 0.453 | |||
| 2021 | Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, ... ... Bonnefond A, et al. Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications. 12: 995. PMID 33558525 DOI: 10.1038/s41467-021-21276-3 | 0.371 | |||
| 2021 | Bonnefond A, Froguel P. Clustering for a better prediction of type 2 diabetes mellitus. Nature Reviews. Endocrinology. PMID 33526906 DOI: 10.1038/s41574-021-00475-4 | 0.396 | |||
| 2021 | Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, ... ... Bonnefond A, et al. Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications. 12: 24. PMID 33402679 DOI: 10.1038/s41467-020-19366-9 | 0.381 | |||
| 2020 | Vaxillaire M, Bonnefond A, Liatis S, Ben Salem Hachmi L, Jotic A, Boissel M, Gaget S, Durand E, Vaillant E, Derhourhi M, Canouil M, Larcher N, Allegaert F, Medlej R, Chadli A, et al. Monogenic diabetes characteristics in a transnational multicenter study from Mediterranean countries. Diabetes Research and Clinical Practice. 108553. PMID 33242514 DOI: 10.1016/j.diabres.2020.108553 | 0.43 | |||
| 2020 | Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study. Frontiers in Physiology. 11: 564140. PMID 33162895 DOI: 10.3389/fphys.2020.564140 | 0.406 | |||
| 2020 | Bonnefond A, Boissel M, Bolze A, Durand E, Toussaint B, Vaillant E, Gaget S, Graeve F, Dechaume A, Allegaert F, Guilcher DL, Yengo L, Dhennin V, Borys JM, Lu JT, et al. Pathogenic variants in actionable MODY genes are associated with type 2 diabetes. Nature Metabolism. 2: 1126-1134. PMID 33046911 DOI: 10.1038/s42255-020-00294-3 | 0.512 | |||
| 2020 | Baron M, Froguel P, Bonnefond A. [Something new in the genetics of monogenic obesity and its insights into pathophysiology]. Medecine Sciences : M/S. 36: 859-865. PMID 33026327 DOI: 10.1051/medsci/2020156 | 0.415 | |||
| 2020 | Lemoine S, Eladari D, Juillard L, Bonnefond A, Froguel P, Dubourg L. The Case | Hypokalemia and severe renal loss of sodium. Kidney International. 97: 1305-1306. PMID 32444101 DOI: 10.1016/J.Kint.2019.12.022 | 0.373 | |||
| 2020 | Saeed S, Arslan M, Manzoor J, Din SM, Janjua QM, Ayesha H, Ain QT, Inam L, Lobbens S, Vaillant E, Durand E, Derhourhi M, Amanzougarene S, Badreddine A, Berberian L, ... ... Bonnefond A, et al. Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence (≥49%) in an Inbred Population of Pakistan. Diabetes. PMID 32349990 DOI: 10.2337/Db19-1238 | 0.522 | |||
| 2020 | El Shamieh S, Stathopoulou MG, Bonnefond A, Ndiaye NC, Lecoeur C, Meyre D, Dadé S, Chedid P, Salami A, Shahabi P, Dedoussis GV, Froguel P, Visvikis-Siest S. Obesity status modifies the association between rs7556897T>C in the intergenic region SLC19A3-CCL20 and blood pressure in French children. Clinical Chemistry and Laboratory Medicine. PMID 32238601 DOI: 10.1515/Cclm-2019-0292 | 0.482 | |||
| 2020 | Tenenbaum M, Plaisance V, Boutry R, Pawlowski V, Jacovetti C, Sanchez-Parra C, Ezanno H, Bourry J, Beeler N, Pasquetti G, Gmyr V, Dalle S, Kerr-Conte J, Pattou F, Hirai SI, ... ... Bonnefond A, et al. The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development. Cellular and Molecular Life Sciences : Cmls. PMID 32189007 DOI: 10.1007/S00018-020-03499-7 | 0.465 | |||
| 2020 | Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study Frontiers in Physiology. 11. DOI: 10.3389/fphys.2020.564140 | 0.421 | |||
| 2019 | Thériault S, Dina C, Messika-Zeitoun D, Le Scouarnec S, Capoulade R, Gaudreault N, Rigade S, Li Z, Simonet F, Lamontagne M, Clavel MA, Arsenault BJ, Boureau AS, Lecointe S, Baron E, ... ... Bonnefond A, et al. Genetic Association Analyses Highlight , , and As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis. Circulation. Genomic and Precision Medicine. 12: e002617. PMID 32141789 DOI: 10.1161/CIRCGEN.119.002617 | 0.353 | |||
| 2019 | Baron M, Maillet J, Huyvaert M, Dechaume A, Boutry R, Loiselle H, Durand E, Toussaint B, Vaillant E, Philippe J, Thomas J, Ghulam A, Franc S, Charpentier G, Borys JM, ... ... Bonnefond A, et al. Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension. Nature Medicine. PMID 31700171 DOI: 10.1038/S41591-019-0622-0 | 0.724 | |||
| 2019 | Schmidt AF, Holmes MV, Preiss D, Swerdlow DI, Denaxas S, Fatemifar G, Faraway R, Finan C, Valentine D, Fairhurst-Hunter Z, Hartwig FP, Horta BL, Hypponen E, Power C, Moldovan M, ... ... Bonnefond A, et al. Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. Bmc Cardiovascular Disorders. 19: 240. PMID 31664920 DOI: 10.1186/S12872-019-1187-Z | 0.456 | |||
| 2019 | Bradfield JP, Vogelezang S, Felix JF, Chesi A, Helgeland Ø, Horikoshi M, Karhunen V, Lowry E, Cousminer DL, Ahluwalia TS, Thiering E, Boh ET, Zafarmand MH, Vilor-Tejedor N, Wang CA, ... ... Bonnefond A, et al. A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity. Human Molecular Genetics. PMID 31504550 DOI: 10.1093/Hmg/Ddz161 | 0.518 | |||
| 2019 | Canouil M, Bouland GA, Bonnefond A, Froguel P, 't Hart LM, Slieker RC. NACHO: an R package for quality control of NanoString nCounter data. Bioinformatics (Oxford, England). PMID 31504159 DOI: 10.1093/Bioinformatics/Btz647 | 0.385 | |||
| 2019 | Ndiaye FK, Huyvaert M, Ortalli A, Canouil M, Lecoeur C, Verbanck M, Lobbens S, Khamis A, Marselli L, Marchetti P, Kerr-Conte J, Pattou F, Marre M, Roussel R, Balkau B, ... ... Bonnefond A, et al. The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward. International Journal of Obesity (2005). PMID 31388097 DOI: 10.1038/S41366-019-0428-7 | 0.505 | |||
| 2019 | Vaxillaire M, Froguel P, Bonnefond A. How Recent Advances in Genomics Improve Precision Diagnosis and Personalized Care of Maturity-Onset Diabetes of the Young. Current Diabetes Reports. 19: 79. PMID 31385057 DOI: 10.1007/S11892-019-1202-X | 0.516 | |||
| 2019 | Khamis A, Canouil M, Siddiq A, Crouch H, Falchi M, Bulow MV, Ehehalt F, Marselli L, Distler M, Richter D, Weitz J, Bokvist K, Xenarios I, Thorens B, Schulte AM, ... ... Bonnefond A, et al. Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes. Molecular Metabolism. PMID 30956117 DOI: 10.1016/J.Molmet.2019.03.004 | 0.538 | |||
| 2019 | Frade-Proud'Hon-Clerc S, Smol T, Frenois F, Sand O, Vaillant E, Dhennin V, Bonnefond A, Froguel P, Fumery M, Guillon-Dellac N, Gower-Rousseau C, Vasseur F. A Novel Rare Missense Variation of the Gene: Evidencesof Implication in Crohn's Disease. International Journal of Molecular Sciences. 20. PMID 30769939 DOI: 10.3390/Ijms20040835 | 0.434 | |||
| 2019 | Bonnefond A, Froguel P, Study LESIRG. 29-OR: High Prevalence of Pathogenic Mutations in Genes Causing Monogenic Diabetes among Patients with Common Type 2 Diabetes Diabetes. 68. DOI: 10.2337/Db19-29-Or | 0.542 | |||
| 2019 | Imam A, Winnebeck E, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Functional circadian and sleep phenotyping of type 2 diabetes patients with melatonin receptor 2 mutations and controls: a pilot study Sleep Medicine. 64: S166-S167. DOI: 10.1016/j.sleep.2019.11.460 | 0.42 | |||
| 2018 | Parmar P, Lowry E, Cugliari G, Suderman M, Wilson R, Karhunen V, Andrew T, Wiklund P, Wielscher M, Guarrera S, Teumer A, Lehne B, Milani L, de Klein N, Mishra PP, ... ... Bonnefond A, et al. Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults. Ebiomedicine. PMID 30442561 DOI: 10.1016/J.Ebiom.2018.10.066 | 0.398 | |||
| 2018 | Karamitri A, Plouffe B, Bonnefond A, Chen M, Gallion J, Guillaume JL, Hegron A, Boissel M, Canouil M, Langenberg C, Wareham NJ, Le Gouill C, Lukasheva V, Lichtarge O, Froguel P, et al. Type 2 diabetes-associated variants of the MT melatonin receptor affect distinct modes of signaling. Science Signaling. 11. PMID 30154102 DOI: 10.1126/Scisignal.Aan6622 | 0.494 | |||
| 2018 | Montagne L, Derhourhi M, Piton A, Toussaint B, Durand E, Vaillant E, Thuillier D, Gaget S, De Graeve F, Rabearivelo I, Lansiaux A, Lenne B, Sukno S, Desailloud R, Cnop M, ... ... Bonnefond A, et al. CoDE-seq, an augmented whole-exome sequencing, enables the accurate detection of CNVs and mutations in Mendelian obesity and intellectual disability. Molecular Metabolism. PMID 29784605 DOI: 10.1016/J.Molmet.2018.05.005 | 0.499 | |||
| 2018 | Abderrahmani A, Yengo L, Caiazzo R, Canouil M, Cauchi S, Raverdy V, Plaisance V, Pawlowski V, Lobbens S, Maillet J, Rolland L, Boutry R, Queniat G, Kwapich M, Tenenbaum M, ... ... Bonnefond A, et al. Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity Associated Type 2 Diabetes. Diabetes. PMID 29728363 DOI: 10.2337/Db17-1539 | 0.479 | |||
| 2018 | Griscelli F, Ezanno H, Soubeyrand M, Feraud O, Oudrhiri N, Bonnefond A, Turhan AG, Froguel P, Bennaceur-Griscelli A. Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 3 (MODY3) carrying a hepatocyte nuclear factor 1-alpha (HNF1A) mutation. Stem Cell Research. 29: 56-59. PMID 29597128 DOI: 10.1016/J.Scr.2018.02.017 | 0.528 | |||
| 2018 | Saeed S, Bonnefond A, Tamanini F, Mirza MU, Manzoor J, Janjua QM, Din SM, Gaitan J, Milochau A, Durand E, Vaillant E, Haseeb A, De Graeve F, Rabearivelo I, Sand O, et al. Loss-of-function mutations in ADCY3 cause monogenic severe obesity. Nature Genetics. PMID 29311637 DOI: 10.1038/S41588-017-0023-6 | 0.512 | |||
| 2018 | Tenenbaum M, Bonnefond A, Froguel P, Abderrahmani A. Physiopathologie du diabète Revue Francophone Des Laboratoires. 2018: 26-32. DOI: 10.1016/S1773-035X(18)30145-X | 0.524 | |||
| 2017 | Rabhi N, Hannou SA, Gromada X, Salas E, Yao X, Oger F, Carney C, Lopez-Mejia IC, Durand E, Rabearivelo I, Bonnefond A, Caron E, Fajas L, Dani C, Froguel P, et al. Cdkn2a deficiency promotes adipose tissue browning. Molecular Metabolism. PMID 29237539 DOI: 10.1016/J.Molmet.2017.11.012 | 0.525 | |||
| 2017 | Foucan L, Larifla L, Durand E, Rambhojan C, Armand C, Michel CT, Billy R, Dhennin V, De Graeve F, Rabearivelo I, Sand O, Lacorte JM, Froguel P, Bonnefond A. High Prevalence of Rare Monogenic Forms of Obesity in Obese Guadeloupean Afro-Caribbean Children. The Journal of Clinical Endocrinology and Metabolism. PMID 29216354 DOI: 10.1210/Jc.2017-01956 | 0.463 | |||
| 2017 | Bonnefond A, Froguel P. Disentangling the Role of Melatonin and its Receptor MTNR1B in Type 2 Diabetes: Still a Long Way to Go? Current Diabetes Reports. 17: 122. PMID 29063374 DOI: 10.1007/S11892-017-0957-1 | 0.539 | |||
| 2017 | Hancili S, Bonnefond A, Philippe J, Vaillant E, De Graeve F, Sand O, Busiah K, Robert JJ, Polak M, Froguel P, Güven A, Vaxillaire M. A novel NEUROG3 mutation in neonatal diabetes associated with a neuro-intestinal syndrome. Pediatric Diabetes. PMID 28940958 DOI: 10.1111/Pedi.12576 | 0.745 | |||
| 2017 | Griscelli F, Feraud O, Ernault T, Oudrihri N, Turhan AG, Bonnefond A, Froguel P, Bennaceur-Griscelli A. Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 13 (MODY13) with a the potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) mutation. Stem Cell Research. 23: 178-181. PMID 28925365 DOI: 10.1016/J.Scr.2017.07.023 | 0.517 | |||
| 2017 | Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, ... ... Bonnefond A, et al. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Plos Medicine. 14: e1002383. PMID 28898252 DOI: 10.1371/Journal.Pmed.1002383 | 0.554 | |||
| 2017 | Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, ... ... Bonnefond A, et al. Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Plos Genetics. 13: e1006972. PMID 28832619 DOI: 10.1371/Journal.Pgen.1006972 | 0.327 | |||
| 2017 | Ndiaye FK, Ortalli A, Canouil M, Huyvaert M, Salazar-Cardozo C, Lecoeur C, Verbanck M, Pawlowski V, Boutry R, Durand E, Rabearivelo I, Sand O, Marselli L, Kerr-Conte J, Chandra V, ... ... Bonnefond A, et al. Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion. Molecular Metabolism. 6: 459-470. PMID 28580277 DOI: 10.1016/J.Molmet.2017.03.011 | 0.48 | |||
| 2017 | Juge PA, Borie R, Kannengiesser C, Gazal S, Revy P, Wemeau-Stervinou L, Debray MP, Ottaviani S, Marchand-Adam S, Nathan N, Thabut G, Richez C, Nunes H, Callebaut I, Justet A, ... ... Bonnefond A, et al. Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis. The European Respiratory Journal. 49. PMID 28495692 DOI: 10.1183/13993003.02314-2016 | 0.446 | |||
| 2017 | Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, ... ... Bonnefond A, et al. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Plos Genetics. 13: e1006528. PMID 28448500 DOI: 10.1371/Journal.Pgen.1006528 | 0.476 | |||
| 2017 | Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, ... ... Bonnefond A, et al. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications. 8: 14977. PMID 28443625 DOI: 10.1038/Ncomms14977 | 0.488 | |||
| 2017 | Antúnez-Ortiz DL, Flores-Alfaro E, Burguete-García AI, Bonnefond A, Peralta-Romero J, Froguel P, Espinoza-Rojo M, Cruz M. Copy Number Variations in Candidate Genes and Intergenic Regions Affect Body Mass Index and Abdominal Obesity in Mexican Children. Biomed Research International. 2017: 2432957. PMID 28428959 DOI: 10.1155/2017/2432957 | 0.481 | |||
| 2017 | Saeed S, Bonnefond A, Manzoor J, Shabbir F, Ayesha H, Philippe J, Durand E, Crouch H, Sand O, Ali M, Butt T, Rathore AW, Falchi M, Arslan M, Froguel P. Erratum: Genetic variants in LEP, LEPR, and MC4R explain 30% of severe obesity in children from a consanguineous population. Obesity (Silver Spring, Md.). 25: 807. PMID 28349664 DOI: 10.1002/oby.21803 | 0.689 | |||
| 2017 | Bonnefond A, Froguel P. The case for too little melatonin signalling in increased diabetes risk. Diabetologia. PMID 28314944 DOI: 10.1007/S00125-017-4255-X | 0.527 | |||
| 2017 | Bonnefond A, Yengo L, Dechaume A, Canouil M, Castelain M, Roger E, Allegaert F, Caiazzo R, Raverdy V, Pigeyre M, Arredouani A, Borys JM, Lévy-Marchal C, Weill J, Roussel R, et al. Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach. Bmc Medicine. 15: 37. PMID 28228143 DOI: 10.1186/S12916-017-0784-X | 0.444 | |||
| 2017 | Tenenbaum M, Ezanno H, Plaisance V, Bricambert J, Boutry R, Beeler N, Bonnefond A, Kerr-Conte J, Pattou F, Froguel P, Abderrahmani A. C-Jun amino terminal kinase 3 (JNK3) contrôle la masse fonctionnelle de la cellule bêta en réponse à l’obésité Diabetes & Metabolism. 43. DOI: 10.1016/S1262-3636(17)30221-5 | 0.405 | |||
| 2017 | Vaxillaire M, Lecoeur C, Durand E, Vaillant E, Toussaint B, Leloire A, Graeve FD, Rabearivelo I, Sand O, Bonnefond A, Froguel P. Mutations exomiques rares transmises au sein de familles de type MODY : analyse de corrélation avec la variabilité phénotypique et les défauts métaboliques précoces Diabetes & Metabolism. 43. DOI: 10.1016/S1262-3636(17)30152-0 | 0.488 | |||
| 2017 | Ndiaye Fk, Ortalli A, Huyvaert M, Salazar-Cardozo C, Canouil M, Kerr-Conte J, Pattou F, Marselli L, Marchetti P, Scharfmann R, Froguel P, Bonnefond A. Identification de 4 nouveaux gènes à risque de diabète de type 2 modulant la fonction β pancréatique et l’insulino-sécrétion Diabetes & Metabolism. 43. DOI: 10.1016/S1262-3636(17)30151-9 | 0.443 | |||
| 2017 | Juge PA, Borie R, Kannengiesser C, Gazal S, Revy P, Wemeau-Stervinou L, Debray MP, Ottaviani S, Marchand-Adam S, Nathan N, Thabut G, Richez C, Nunes H, Callebaut I, Justet A, ... ... Bonnefond A, et al. Fond génétique partagé entre la pneumopathie interstitielle diffuse associée à la polyarthrite rhumatoïde et la fibrose pulmonaire idiopathique Revue Des Maladies Respiratoires. 34. DOI: 10.1016/J.Rmr.2016.10.133 | 0.479 | |||
| 2016 | Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C, Moldovan M, van Iperen E, Hovingh GK, Demuth I, Norman K, ... ... Bonnefond A, et al. PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. The Lancet. Diabetes & Endocrinology. PMID 27908689 DOI: 10.1016/S2213-8587(16)30396-5 | 0.519 | |||
| 2016 | Bricambert J, Favre D, Brajkovic S, Bonnefond A, Boutry R, Salvi R, Plaisance V, Chikri M, Chinetti-Gbaguidi G, Staels B, Giusti V, Caiazzo R, Pattou F, Waeber G, Froguel P, et al. Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function. Molecular Metabolism. 5: 1200-1207. PMID 27900262 DOI: 10.1016/J.Molmet.2016.09.011 | 0.453 | |||
| 2016 | Yengo L, Arredouani A, Marre M, Roussel R, Vaxillaire M, Falchi M, Haoudi A, Tichet J, Balkau B, Bonnefond A, Froguel P. Impact of statistical models on the prediction of type 2 diabetes using non-targeted metabolomics profiling. Molecular Metabolism. 5: 918-25. PMID 27689004 DOI: 10.1016/J.Molmet.2016.08.011 | 0.49 | |||
| 2016 | Plaisance V, Brajkovic S, Tenenbaum M, Favre D, Ezanno H, Bonnefond A, Bonner C, Gmyr V, Kerr-Conte J, Gauthier BR, Widmann C, Waeber G, Pattou F, Froguel P, Abderrahmani A. Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL. Plos One. 11: e0163046. PMID 27636901 DOI: 10.1371/Journal.Pone.0163046 | 0.413 | |||
| 2016 | Bonnefond A, Karamitri A, Jockers R, Froguel P. The Difficult Journey from Genome-wide Association Studies to Pathophysiology: The Melatonin Receptor 1B (MT2) Paradigm. Cell Metabolism. 24: 345-7. PMID 27626190 DOI: 10.1016/J.Cmet.2016.08.015 | 0.502 | |||
| 2016 | Morandi A, Bonnefond A, Lobbens S, Yengo L, Miraglia Del Giudice E, Grandone A, Lévy-Marchal C, Weill J, Maffeis C, Froguel P. Associations between type 2 diabetes-related genetic scores and metabolic traits, in obese and normal-weight youths. The Journal of Clinical Endocrinology and Metabolism. jc20162432. PMID 27588439 DOI: 10.1210/Jc.2016-2432 | 0.555 | |||
| 2016 | Vaxillaire M, Bonnefond A, Froguel P. Comment on Beltrand et al. Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations. Diabetes Care 2015;38:2033-2041. Diabetes Care. 39: e153-4. PMID 27555630 DOI: 10.2337/Dc15-2703 | 0.504 | |||
| 2016 | Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Bonnefond A, et al. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 12: e1006166. PMID 27355579 DOI: 10.1371/Journal.Pgen.1006166 | 0.348 | |||
| 2016 | Bonnefond A, Keller R, Meyre D, Stutzmann F, Thuillier D, Stefanov DG, Froguel P, Horber FF, Kral JG. Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A Six-Year Prospective Study. Diabetes Care. PMID 27222505 DOI: 10.2337/Dc16-0115 | 0.435 | |||
| 2016 | Lamri A, Bonnefond A, Meyre D, Balkau B, Roussel R, Marre M, Froguel P, Fumeron F. Interaction between GPR120 p.R270H loss-of-function variant and dietary fat intake on incident type 2 diabetes risk in the D.E.S.I.R. study Nutrition Metabolism and Cardiovascular Diseases. 26: 931-936. PMID 27212621 DOI: 10.1016/J.Numecd.2016.04.010 | 0.481 | |||
| 2016 | Rabhi N, Denechaud PD, Gromada X, Hannou SA, Zhang H, Rashid T, Salas E, Durand E, Sand O, Bonnefond A, Yengo L, Chavey C, Bonner C, Kerr-Conte J, Abderrahmani A, et al. KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response. Cell Reports. PMID 27117420 DOI: 10.1016/J.Celrep.2016.03.079 | 0.482 | |||
| 2016 | Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, ... ... Bonnefond A, et al. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications. 7: 10495. PMID 26833246 DOI: 10.1038/Ncomms10495 | 0.491 | |||
| 2016 | Ndiaye F, Ortalli A, Verbanck M, Huyvaert M, Salazar-Cardozo C, Yengo L, Marselli L, Marchetti P, Froguel P, Bonnefond A. CO-68: L'étude génomique et fonctionnelle des gènes du diabète de type 2 confirme leur rôle dans les cellules beta-pancréatiques Diabetes & Metabolism. 42. DOI: 10.1016/S1262-3636(16)30086-6 | 0.481 | |||
| 2016 | Juge PA, Borie R, Kannengiesser C, Gazal S, Revy P, Wemeau-Stervinou L, Debray MP, Ottaviani S, Marchand-Adam S, Nathan N, Thabut G, Richez C, Nunes H, Callebaut I, Justet A, ... ... Bonnefond A, et al. Fond génétique partagé entre la pneumopathie interstitielle diffuse associée à la polyarthrite rhumatoïde et la fibrose pulmonaire idiopathique Revue Du Rhumatisme. 83. DOI: 10.1016/S1169-8330(16)30345-3 | 0.431 | |||
| 2015 | Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Møller E, Mahajan A, Pitkänen N, Joro R, Cavadino A, Huikari V, ... ... Bonnefond A, et al. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics. PMID 26604143 DOI: 10.1093/Hmg/Ddv472 | 0.469 | |||
| 2015 | Philippe J, Derhourhi M, Durand E, Vaillant E, Dechaume A, Rabearivelo I, Dhennin V, Vaxillaire M, De Graeve F, Sand O, Froguel P, Bonnefond A. What Is the Best NGS Enrichment Method for the Molecular Diagnosis of Monogenic Diabetes and Obesity? Plos One. 10: e0143373. PMID 26599467 DOI: 10.1371/Journal.Pone.0143373 | 0.726 | |||
| 2015 | Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Bonnefond A, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 11: e1005378. PMID 26426971 DOI: 10.1371/Journal.Pgen.1005378 | 0.445 | |||
| 2015 | Saeed S, Bonnefond A, Manzoor J, Shabir F, Ayesha H, Philippe J, Durand E, Crouch H, Sand O, Ali M, Butt T, Rathore AW, Falchi M, Arslan M, Froguel P. Genetic variants in LEP, LEPR, and MC4R explain 30% of severe obesity in children from a consanguineous population. Obesity (Silver Spring, Md.). 23: 1687-95. PMID 26179253 DOI: 10.1002/Oby.21142 | 0.726 | |||
| 2015 | Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stančáková A, Faul JD, Zhao W, Bartz TM, ... ... Bonnefond A, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 523: 459-62. PMID 26131930 DOI: 10.1038/Nature14618 | 0.455 | |||
| 2015 | Morandi A, Bonnefond A, Lobbens S, Carotenuto M, Del Giudice EM, Froguel P, Maffeis C. A girl with incomplete Prader-Willi syndrome and negative MS-PCR, found to have mosaic maternal UPD-15 at SNP array. American Journal of Medical Genetics. Part A. 167: 2720-6. PMID 26109092 DOI: 10.1002/Ajmg.A.37222 | 0.419 | |||
| 2015 | Bonnefond A, Yengo L, Le May C, Fumeron F, Marre M, Balkau B, Charpentier G, Franc S, Froguel P, Cariou B. The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis. Diabetologia. PMID 26049403 DOI: 10.1007/S00125-015-3659-8 | 0.519 | |||
| 2015 | Bonnefond A, Lamri A, Leloire A, Vaillant E, Roussel R, Lévy-Marchal C, Weill J, Galan P, Hercberg S, Ragot S, Hadjadj S, Charpentier G, Balkau B, Marre M, Fumeron F, et al. Contribution of the low-frequency, loss-of-function p.R270H mutation in FFAR4 (GPR120) to increased fasting plasma glucose levels. Journal of Medical Genetics. 52: 595-8. PMID 26025001 DOI: 10.1136/Jmedgenet-2015-103065 | 0.513 | |||
| 2015 | Bonnefond A, Froguel P. Rare and common genetic events in type 2 diabetes: what should biologists know? Cell Metabolism. 21: 357-68. PMID 25640731 DOI: 10.1016/J.Cmet.2014.12.020 | 0.537 | |||
| 2015 | Mejía-Benítez MA, Bonnefond A, Yengo L, Huyvaert M, Dechaume A, Peralta-Romero J, Klünder-Klünder M, García Mena J, El-Sayed Moustafa JS, Falchi M, Cruz M, Froguel P. Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children. Diabetologia. 58: 290-4. PMID 25394825 DOI: 10.1007/S00125-014-3441-3 | 0.507 | |||
| 2015 | Philippe J, Stijnen P, Meyre D, De Graeve F, Thuillier D, Delplanque J, Gyapay G, Sand O, Creemers JW, Froguel P, Bonnefond A. A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity. International Journal of Obesity (2005). 39: 295-302. PMID 24890885 DOI: 10.1038/Ijo.2014.96 | 0.714 | |||
| 2015 | Neve B, Ortalli A, Leloire A, Feraud O, Pasquetti G, Vaxillaire M, Bonnefond A, Bennaceur-Griscelli A, Kerr-Conte J, Froguel P. P202 Utilisation des cellules souches somatiques pour modéliser le diabète monogénique lié aux anomalies du canal potassique de KCNJ11 Diabetes & Metabolism. 41. DOI: 10.1016/S1262-3636(15)30315-3 | 0.508 | |||
| 2015 | Mejia MA, Yengo L, Lobbens S, Valladares-Salgado A, Eralta J, Garcia J, Cruz M, Froguel P, Bonnefond A. PO11 Deux nouveaux loci associés au diabète de type 2 dans la population mexicaine identifiés par les puces Metabochip Diabetes & Metabolism. 41. DOI: 10.1016/S1262-3636(15)30088-4 | 0.32 | |||
| 2015 | Vaxillaire M, Bonnefond A, Philippe J, Vaillant E, Durand E, Sand O, Busiah K, Scharfmann R, Hafez M, Hancili S, Polak M, Froguel P. O59 Identification de nouvelles mutations associées au diabète néonatal grâce à l’utilisation de techniques (pan) génomiques incluant le séquençage de nouvelle génération Diabetes & Metabolism. 41. DOI: 10.1016/S1262-3636(15)30059-8 | 0.687 | |||
| 2015 | Bonnefond A, Yengo L, Balkau B, Marre M, Brousseau T, Froguel P. O52 L’activité enzymatique plasmatique de l’amylase pancréatique est associée à une diminution de l’indice de masse corporelle et protège du risque de diabète dans la cohorte D.E.S.I.R. Diabetes & Metabolism. 41. DOI: 10.1016/S1262-3636(15)30052-5 | 0.467 | |||
| 2015 | Cariou B, Yengo L, May CL, Marre M, Balkau B, Franc S, Froguel P, Bonnefond A. O06 Le mutant perte de fonction p.R46L de PCSK9 n’est pas associé à un risque accru de diabète chez l’homme Diabetes & Metabolism. 41. DOI: 10.1016/S1262-3636(15)30006-9 | 0.323 | |||
| 2014 | Montagne L, Raimondo A, Delobel B, Duban-Bedu B, Noblet FS, Dechaume A, Bersten DC, Meyre D, Whitelaw ML, Froguel P, Bonnefond A. Identification of two novel loss-of-function SIM1 mutations in two overweight children with developmental delay. Obesity (Silver Spring, Md.). 22: 2621-4. PMID 25234154 DOI: 10.1002/Oby.20886 | 0.49 | |||
| 2014 | Vaxillaire M, Yengo L, Lobbens S, Rocheleau G, Eury E, Lantieri O, Marre M, Balkau B, Bonnefond A, Froguel P. Type 2 diabetes-related genetic risk scores associated with variations in fasting plasma glucose and development of impaired glucose homeostasis in the prospective DESIR study. Diabetologia. 57: 1601-10. PMID 24893864 DOI: 10.1007/S00125-014-3277-X | 0.539 | |||
| 2014 | Falchi M, El-Sayed Moustafa JS, Takousis P, Pesce F, Bonnefond A, Andersson-Assarsson JC, Sudmant PH, Dorajoo R, Al-Shafai MN, Bottolo L, Ozdemir E, So HC, Davies RW, Patrice A, Dent R, et al. Low copy number of the salivary amylase gene predisposes to obesity. Nature Genetics. 46: 492-7. PMID 24686848 DOI: 10.1038/Ng.2939 | 0.511 | |||
| 2014 | Abdelalim EM, Bonnefond A, Bennaceur-Griscelli A, Froguel P. Pluripotent stem cells as a potential tool for disease modelling and cell therapy in diabetes. Stem Cell Reviews. 10: 327-37. PMID 24577791 DOI: 10.1007/S12015-014-9503-6 | 0.504 | |||
| 2014 | Saeed S, Bonnefond A, Manzoor J, Philippe J, Durand E, Arshad M, Sand O, Butt TA, Falchi M, Arslan M, Froguel P. Novel LEPR mutations in obese Pakistani children identified by PCR-based enrichment and next generation sequencing. Obesity (Silver Spring, Md.). 22: 1112-7. PMID 24319006 DOI: 10.1002/Oby.20667 | 0.717 | |||
| 2014 | Bonnefond A, Philippe J, Durand E, Muller J, Saeed S, Arslan M, MartÃnez R, De Graeve F, Dhennin V, Rabearivelo I, Polak M, Cavé H, Castaño L, Vaxillaire M, Mandel JL, et al. Highly sensitive diagnosis of 43 monogenic forms of diabetes or obesity through one-step PCR-based enrichment in combination with next-generation sequencing. Diabetes Care. 37: 460-7. PMID 24041679 DOI: 10.2337/Dc13-0698 | 0.737 | |||
| 2014 | Bonnefond A, Saeed S, Manzoor J, Philippe J, Durand E, Sand O, Butt T, Falchi M, Arslan M, Froguel P. PO13 Identification par séquençage de nouvelle génération de deux nouvelles mutations situées dans LEPR, chez des enfants pakistanais avec une obésité sévère et issus de familles consanguines Diabetes & Metabolism. 40. DOI: 10.1016/S1262-3636(14)72271-2 | 0.715 | |||
| 2014 | Vaxillaire M, Yengo L, Lobbens S, Rocheleau G, Eury E, Lantieri O, Marre M, Balkau B, Bonnefond A, Froguel P. O31 Deux scores de risque génétique sont fortement associés aux variations de glycémie à jeun et à l’incidence d’hyperglycémie et de diabète de type 2 dans l’étude prospective D.E.S.I.R Diabetes & Metabolism. 40. DOI: 10.1016/S1262-3636(14)72205-0 | 0.481 | |||
| 2014 | Rabhi N, Denechaud P, Salas E, Bonnefond A, Bettignies CD, Froguel P, Annicotte J. O5 La lysine acetyl-transferase P300/CBP-associated factor (PCAF) contrôle la sécrétion d’insuline et la réponse au stress du reticulum Diabetes & Metabolism. 40. DOI: 10.1016/S1262-3636(14)72179-2 | 0.467 | |||
| 2013 | Busiah K, Drunat S, Vaivre-Douret L, Bonnefond A, Simon A, Flechtner I, Gérard B, Pouvreau N, Elie C, Nimri R, De Vries L, Tubiana-Rufi N, Metz C, Bertrand AM, Nivot-Adamiak S, et al. Neuropsychological dysfunction and developmental defects associated with genetic changes in infants with neonatal diabetes mellitus: a prospective cohort study [corrected]. The Lancet. Diabetes & Endocrinology. 1: 199-207. PMID 24622368 DOI: 10.1016/S2213-8587(13)70059-7 | 0.525 | |||
| 2013 | Bonnefond A, Froguel P. Next-generation sequencing for identifying new genes in rare genetic diseases: many challenges and a pinch of luck. Genome Biology. 14: 309. PMID 23899211 DOI: 10.1186/Gb-2013-14-7-309 | 0.464 | |||
| 2013 | Bonnefond A, Skrobek B, Lobbens S, Eury E, Thuillier D, Cauchi S, Lantieri O, Balkau B, Riboli E, Marre M, Charpentier G, Yengo L, Froguel P. Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications. Nature Genetics. 45: 1040-3. PMID 23852171 DOI: 10.1038/Ng.2700 | 0.526 | |||
| 2013 | Bonnefond A, Raimondo A, Stutzmann F, Ghoussaini M, Ramachandrappa S, Bersten DC, Durand E, Vatin V, Balkau B, Lantieri O, Raverdy V, Pattou F, Van Hul W, Van Gaal L, Peet DJ, et al. Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features. The Journal of Clinical Investigation. 123: 3037-41. PMID 23778136 DOI: 10.1172/Jci68035 | 0.508 | |||
| 2013 | Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, ... ... Bonnefond A, et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. Plos Genetics. 9: e1003500. PMID 23754948 DOI: 10.1371/Journal.Pgen.1003500 | 0.471 | |||
| 2013 | Bonnefond A, Vaillant E, Philippe J, Skrobek B, Lobbens S, Yengo L, Huyvaert M, Cavé H, Busiah K, Scharfmann R, Polak M, Abdul-Rasoul M, Froguel P, Vaxillaire M. Transcription factor gene MNX1 is a novel cause of permanent neonatal diabetes in a consanguineous family. Diabetes & Metabolism. 39: 276-80. PMID 23562494 DOI: 10.1016/J.Diabet.2013.02.007 | 0.748 | |||
| 2013 | Baerenwald DA, Bonnefond A, Bouatia-Naji N, Flemming BP, Umunakwe OC, Oeser JK, Pound LD, Conley NL, Cauchi S, Lobbens S, Eury E, Balkau B, Lantieri O, Dadi PK, et al. Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels. Diabetologia. 56: 1306-16. PMID 23508304 DOI: 10.1007/S00125-013-2875-3 | 0.43 | |||
| 2013 | Bonnefond A, Saulnier PJ, Stathopoulou MG, Grarup N, Ndiaye NC, Roussel R, Nezhad MA, Dechaume A, Lantieri O, Hercberg S, Lauritzen T, Balkau B, El-Sayed Moustafa JS, Hansen T, Pedersen O, et al. What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications? Plos One. 8: e55921. PMID 23405237 DOI: 10.1371/Journal.Pone.0055921 | 0.495 | |||
| 2013 | MejÃa-BenÃtez A, Klünder-Klünder M, Yengo L, Meyre D, Aradillas C, Cruz E, Pérez-Luque E, Malacara JM, Garay ME, Peralta-Romero J, Flores-Huerta S, GarcÃa-Mena J, Froguel P, Cruz M, Bonnefond A. Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4R genes to obesity in Mexican children. Bmc Medical Genetics. 14: 21. PMID 23375129 DOI: 10.1186/1471-2350-14-21 | 0.5 | |||
| 2013 | Bonnefond A, Yengo L, Philippe J, Dechaume A, Ezzidi I, Vaillant E, Gjesing AP, Andersson EA, Czernichow S, Hercberg S, Hadjadj S, Charpentier G, Lantieri O, Balkau B, Marre M, et al. Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes. Diabetologia. 56: 492-6. PMID 23224494 DOI: 10.1007/S00125-012-2794-8 | 0.747 | |||
| 2013 | Robiou-du-Pont S, Bonnefond A, Yengo L, Vaillant E, Lobbens S, Durand E, Weill J, Lantieri O, Balkau B, Charpentier G, Marre M, Froguel P, Meyre D. Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population International Journal of Obesity. 37: 980-985. PMID 23090577 DOI: 10.1038/Ijo.2012.175 | 0.547 | |||
| 2013 | Froguel P, Bonnefond A. Does Type 2 diabetes increase the risk of developing cancer Diabetes Management. 3: 439-441. DOI: 10.2217/Dmt.13.49 | 0.454 | |||
| 2013 | Philippe J, Durand E, Vaxillaire M, Sand O, De Graeve F, Cavé H, Polak M, Martínez Salazar R, Castano L, Muller J, Mandel J, Saeed S, Bonnefond A, Froguel P. PO27 Diagnostic moléculaire simultané de 43 formes monogéniques de diabète et d’obésité : un pas vers la médecine métabolique Personnalisée Diabetes & Metabolism. 39: A27. DOI: 10.1016/S1262-3636(13)71723-3 | 0.679 | |||
| 2013 | Bonnefond A, Skrobek B, Lobbens S, Eury E, Balkau B, Riboli E, Marre M, Charpentier G, Yengo L, Froguel P. O61 Le diabète de type 2 est responsable d’anomalies chromosomiques somatiques en mosaïques qui sont pré-cancéreuses Diabetes & Metabolism. 39. DOI: 10.1016/S1262-3636(13)71673-2 | 0.48 | |||
| 2013 | Annicotte J-, Denechaud P-, Rabhi N, Bonnefond A, Bettignies CD, Froguel P. O50 La protéine P300/CBP-associated factor (PCAF) est une histone acetyl-transferase qui contrôle la fonction de la cellule ß pancréatique Diabetes & Metabolism. 39. DOI: 10.1016/S1262-3636(13)71662-8 | 0.485 | |||
| 2012 | Bonnefond A, Sand O, Guerin B, Durand E, De Graeve F, Huyvaert M, Rachdi L, Kerr-Conte J, Pattou F, Vaxillaire M, Polak M, Scharfmann R, Czernichow P, Froguel P. GATA6 inactivating mutations are associated with heart defects and, inconsistently, with pancreatic agenesis and diabetes. Diabetologia. 55: 2845-7. PMID 22806356 DOI: 10.1007/S00125-012-2645-7 | 0.533 | |||
| 2012 | Bonnefond A, Philippe J, Durand E, Dechaume A, Huyvaert M, Montagne L, Marre M, Balkau B, Fajardy I, Vambergue A, Vatin V, Delplanque J, Le Guilcher D, De Graeve F, Lecoeur C, et al. Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene. Plos One. 7: e37423. PMID 22701567 DOI: 10.1371/Journal.Pone.0037423 | 0.721 | |||
| 2012 | Vaxillaire M, Bonnefond A, Froguel P. The lessons of early-onset monogenic diabetes for the understanding of diabetes pathogenesis. Best Practice & Research. Clinical Endocrinology & Metabolism. 26: 171-87. PMID 22498247 DOI: 10.1016/J.Beem.2011.12.001 | 0.543 | |||
| 2012 | Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, ... ... Bonnefond A, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics. 8: e1002607. PMID 22479202 DOI: 10.1371/Journal.Pgen.1002607 | 0.497 | |||
| 2012 | Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, et al. KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron. Nature Genetics. 44: 456-60, S1-3. PMID 22406640 DOI: 10.1038/Ng.2218 | 0.457 | |||
| 2012 | Froguel P, Ndiaye NC, Bonnefond A, Bouatia-Naji N, Dechaume A, Siest G, Herbeth B, Falchi M, Bottolo L, Guéant-Rodriguez RM, Lecoeur C, Langlois MR, Labrune Y, Ruokonen A, El Shamieh S, et al. A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels. Plos One. 7: e32327. PMID 22403646 DOI: 10.1371/Journal.Pone.0032327 | 0.489 | |||
| 2012 | Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, et al. Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature. 483: 350-4. PMID 22343897 DOI: 10.1038/Nature10798 | 0.484 | |||
| 2012 | Bonnefond A, Clément N, Fawcett K, Yengo L, Vaillant E, Guillaume JL, Dechaume A, Payne F, Roussel R, Czernichow S, Hercberg S, Hadjadj S, Balkau B, Marre M, Lantieri O, et al. Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes. Nature Genetics. 44: 297-301. PMID 22286214 DOI: 10.1038/Ng.1053 | 0.518 | |||
| 2012 | Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, ... ... Bonnefond A, et al. A genome-wide association search for type 2 diabetes genes in African Americans. Plos One. 7: e29202. PMID 22238593 DOI: 10.1371/Journal.Pone.0029202 | 0.496 | |||
| 2012 | Walley AJ, Jacobson P, Falchi M, Bottolo L, Andersson JC, Petretto E, Bonnefond A, Vaillant E, Lecoeur C, Vatin V, Jernas M, Balding D, Petteni M, Park YS, Aitman T, et al. Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue. International Journal of Obesity (2005). 36: 137-47. PMID 21427694 DOI: 10.1038/Ijo.2011.22 | 0.485 | |||
| 2012 | Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, et al. Erratum: KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron (Nature Genetics (2012) 44 (458-462)) Nature Genetics. 44. DOI: 10.1038/Ng0512-609 | 0.448 | |||
| 2012 | Polak M, Cavé H, Busiah K, Bonnefond A, Simon A, Flechtner I, Dechaume A, Pouvreau N, Gerard B, Scharfmann R, Froguel P, Vaxillaire M. Diabète néonatal (monogénique de la très petite enfance). État des travaux du Réseau Français d’étude du diabète néonatal. Diabetes & Metabolism. 38. DOI: 10.1016/S1262-3636(12)71525-2 | 0.489 | |||
| 2012 | Vaxillaire M, Bonnefond A, Philippe J, Durand E, Dechaume A, Vaillant E, Montagne L, Huyvaert M, Lecoeur C, Graeve FD, Sand O, Froguel P. O58 Une nouvelle cause curable de MODY et de DT2 de l’adulte jeune révélée par une mutation de KCNJ11, codant la sous-unité Kir6.2 du canal potassique ATP-dépendant Diabetes & Metabolism. 38. DOI: 10.1016/S1262-3636(12)71036-4 | 0.728 | |||
| 2012 | Moustafa JE, Takousis P, Pesce F, Bonnefond A, Carlsson L, Walley A, Pattou F, Spector T, Falchi M, Froguel P. O57 Des variations du nombre de copies au niveau d’un CNV fréquent contribuent très fortement au risque d’obésité Diabetes & Metabolism. 38. DOI: 10.1016/S1262-3636(12)71035-2 | 0.315 | |||
| 2012 | Bonnefond A, Poulain-Godefroy O, Ichimura A, Hirasawa A, Yengo L, Leloire A, Choquet H, Meyre D, Pattou F, Wolowczuk I, Tsujimoto G, Froguel P. O53 L’altération du récepteur des acides gras insaturés de type omega-3 GPR120 entraîne une obésité chez l’Homme et la Souris Diabetes & Metabolism. 38. DOI: 10.1016/S1262-3636(12)71031-5 | 0.479 | |||
| 2011 | Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Mägi R, Meacham S, Okada Y, Pirastu N, ... ... Bonnefond A, et al. New gene functions in megakaryopoiesis and platelet formation. Nature. 480: 201-8. PMID 22139419 DOI: 10.1038/Nature10659 | 0.44 | |||
| 2011 | Semplici F, Vaxillaire M, Fogarty S, Semache M, Bonnefond A, Fontés G, Philippe J, Meur G, Diraison F, Sessions RB, Rutter J, Poitout V, Froguel P, Rutter GA. Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion. The Journal of Biological Chemistry. 286: 44005-14. PMID 22065581 DOI: 10.1074/Jbc.M111.254995 | 0.726 | |||
| 2011 | Gjesing AP, Nielsen AA, Brandslund I, Christensen C, Sandbæk A, Jørgensen T, Witte D, Bonnefond A, Froguel P, Hansen T, Pedersen O. Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes. Bmc Medical Genetics. 12: 99. PMID 21781351 DOI: 10.1186/1471-2350-12-99 | 0.4 | |||
| 2011 | Bonnefond A, Lomberk G, Buttar N, Busiah K, Vaillant E, Lobbens S, Yengo L, Dechaume A, Mignot B, Simon A, Scharfmann R, Neve B, Tanyolaç S, Hodoglugil U, Pattou F, et al. Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus. The Journal of Biological Chemistry. 286: 28414-24. PMID 21592955 DOI: 10.1074/Jbc.M110.215822 | 0.514 | |||
| 2011 | Bonnefond A, Lomberk G, Busiah K, Vaillant E, Pattou F, Iovanna J, Stein R, Polak M, Vaxillaire M, Urrutia R, Froguel P. O2 L’extinction de la biosynthèse d’insuline via l’altération d’un site de fixation du facteur de transcription KLF11 entraîne une forme congénitale de diabète néonatal Diabetes & Metabolism. 37. DOI: 10.1016/S1262-3636(11)70490-6 | 0.495 | |||
| 2010 | Bonnefond A, Durand E, Sand O, De Graeve F, Gallina S, Busiah K, Lobbens S, Simon A, Bellanné-Chantelot C, Létourneau L, Scharfmann R, Delplanque J, Sladek R, Polak M, Vaxillaire M, et al. Molecular diagnosis of neonatal diabetes mellitus using next-generation sequencing of the whole exome. Plos One. 5: e13630. PMID 21049026 DOI: 10.1371/Journal.Pone.0013630 | 0.509 | |||
| 2010 | Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, Reilly MP, Ricketts SL, ... ... Bonnefond A, et al. Common variants at 10 genomic loci influence hemoglobin Aâ‚(C) levels via glycemic and nonglycemic pathways. Diabetes. 59: 3229-39. PMID 20858683 DOI: 10.2337/Db10-0502 | 0.495 | |||
| 2010 | Bonnefond A, Froguel P, Vaxillaire M. The emerging genetics of type 2 diabetes. Trends in Molecular Medicine. 16: 407-16. PMID 20728409 DOI: 10.1016/J.Molmed.2010.06.004 | 0.562 | |||
| 2010 | Bouatia-Naji N, Bonnefond A, Baerenwald DA, Marchand M, Bugliani M, Marchetti P, Pattou F, Printz RL, Flemming BP, Umunakwe OC, Conley NL, Vaxillaire M, Lantieri O, Balkau B, Marre M, et al. Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels. Diabetes. 59: 2662-71. PMID 20622168 DOI: 10.2337/Db10-0389 | 0.446 | |||
| 2010 | Andersson EA, Holst B, Sparsø T, Grarup N, Banasik K, Holmkvist J, Jørgensen T, Borch-Johnsen K, Egerod KL, Lauritzen T, Sørensen TI, Bonnefond A, Meyre D, Froguel P, Schwartz TW, et al. MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans. Diabetes. 59: 1539-48. PMID 20200315 DOI: 10.2337/Db09-1757 | 0.526 | |||
| 2010 | Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Bonnefond A, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics. 42: 105-16. PMID 20081858 DOI: 10.1038/Ng.520 | 0.525 | |||
| 2010 | Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, ... ... Bonnefond A, et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nature Genetics. 42: 142-8. PMID 20081857 DOI: 10.1038/Ng.521 | 0.477 | |||
| 2010 | Meur G, Simon A, Harun N, Virally M, Dechaume A, Bonnefond A, Fetita S, Tarasov AI, Guillausseau PJ, Boesgaard TW, Pedersen O, Hansen T, Polak M, Gautier JF, Froguel P, et al. Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention. Diabetes. 59: 653-61. PMID 20007936 DOI: 10.2337/Db09-1091 | 0.557 | |||
| 2010 | Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Bonnefond A, et al. Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Nature Genetics. 42: 464-464. DOI: 10.1038/Ng0510-464A | 0.52 | |||
| 2010 | Vaxillaire M, Busiah K, Bonnefond A, Lecoeur C, Dechaume A, Simon A, Graeve Fd, Gallina S, Delplanque J, Cavé H, Polak M, Froguel P. P210 Nouvelles Approches dans l’Étude des Diabètes Monogéniques chez l’Enfant et l’Adulte Jeune, et Distribution des Étiologies Génétiques à partir de la Cohorte du Réseau d’Étude Français Diabetes & Metabolism. 36. DOI: 10.1016/S1262-3636(10)70358-X | 0.498 | |||
| 2010 | Bonnefond A, Lomberk G, Busiah K, Dechaume A, Pereira S, Simon A, Cavé H, Mignot B, Polak M, Urrutia R, Froguel P, Vaxillaire M. O9 L’Extinction de l’Activité du Promoteur du Gène de l’Insuline Entraîne une Forme Congénitale de Diabète Néonatal Transitoire Diabetes & Metabolism. 36. DOI: 10.1016/S1262-3636(10)70013-6 | 0.497 | |||
| 2009 | Bouatia-Naji N, Bonnefond A, Froguel P. [Inputs from the genetics of fasting glucose: lessons for diabetes]. Medecine Sciences : M/S. 25: 897-902. PMID 19951660 DOI: 10.1051/Medsci/20092511897 | 0.511 | |||
| 2009 | Bonnefond A, Vaxillaire M, Labrune Y, Lecoeur C, Chèvre JC, Bouatia-Naji N, Cauchi S, Balkau B, Marre M, Tichet J, Riveline JP, Hadjadj S, Gallois Y, Czernichow S, Hercberg S, et al. Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits. Diabetes. 58: 2687-97. PMID 19651813 DOI: 10.2337/Db09-0652 | 0.458 | |||
| 2009 | Vaxillaire M, D P, Bonnefond A, Froguel P. Breakthroughs in monogenic diabetes genetics: from pediatric forms to young adulthood diabetes. Pediatric Endocrinology Reviews : Per. 6: 405-17. PMID 19396026 | 0.479 | |||
| 2009 | Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, et al. G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans. Diabetes. 58: 1450-6. PMID 19324940 DOI: 10.2337/Db08-1660 | 0.519 | |||
| 2009 | Bonnefond A, Bouatia-Naji N, Simon A, Saint-Martin C, Dechaume A, Lonlay Pd, Polak M, Bellanné-Chantelot C, Froguel P, Vaxillaire M. Mutations in G6PC2 do not contribute to monogenic forms of early infancy diabetes and beta cell dysfunction Diabetologia. 52: 982-985. PMID 19238352 DOI: 10.1007/S00125-009-1299-6 | 0.522 | |||
| 2009 | Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De Graeve F, Chèvre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, et al. A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nature Genetics. 41: 89-94. PMID 19060909 DOI: 10.1038/Ng.277 | 0.516 | |||
| 2009 | Bonnefond A, Bouatia-Naji N, Cavalcanti-Proença C, Marchand M, Oeser J, Lévy-Marchal C, Balkau B, Marre M, Pattou F, Jarvelin MR, O’Brien R, Froguel P. O98 Des variants du promoteur du gène G6PC2 pourraient expliquer la contribution de ce locus au contrôle génétique de la glycémie Diabetes & Metabolism. 35. DOI: 10.1016/S1262-3636(09)71790-2 | 0.476 | |||
| 2009 | Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Jarvelin MR, Charpentier G, Hadjadj S, Lévy-Marchal C, Balkau B, Marre M, Visvikis-Siest S, Pedersen O, Froguel P. O97 Des variants du gène MTNR1B du récepteur 2 à la mélatonine augmentent la glycémie et le risque de DT2 : un lien entre le rythme circadien et le diabète ? Diabetes & Metabolism. 35. DOI: 10.1016/S1262-3636(09)71789-6 | 0.464 | |||
| 2009 | Vaxillaire M, Simon A, Bonnefond A, Virally M, Dechaume A, Busiah K, Cavé H, Scharfmann R, Rutter G, Gautier JF, Froguel P, Polak M. O5 Des mutations du gène de la préproinsuline altèrent la maturation de l’insuline et entraînent un diabète non auto-immun chez l’enfant et de type Mody Diabetes & Metabolism. 35. DOI: 10.1016/S1262-3636(09)71697-0 | 0.529 | |||
| 2008 | Taha D, Bardise J, Hegab A, Bonnefond A, Marchand M, Drunat S, Vaxillaire M, Polak M. Neonatal diabetes mellitus because of pancreatic agenesis with dysmorphic features and recurrent bacterial infections. Pediatric Diabetes. 9: 240-4. PMID 18547237 DOI: 10.1111/J.1399-5448.2007.00365.X | 0.392 | |||
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