Jessica Spradlin - Publications

Affiliations: 
2016- University of California, Berkeley, Berkeley, CA, United States 

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Henning NJ, Manford AG, Spradlin JN, Brittain SM, Zhang E, McKenna JM, Tallarico JA, Schirle M, Rape M, Nomura DK. Correction to "Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications". Journal of the American Chemical Society. 145: 21142. PMID 37708357 DOI: 10.1021/jacs.3c09174  0.812
2023 Moon P, Zammit C, Shao Q, Boike L, Dovala D, Henning NJ, Knapp M, Spradlin JN, Ward CC, Wolleb H, Fuller D, Blake G, Murphy JP, Wang F, Lu Y, et al. Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors. Chembiochem : a European Journal of Chemical Biology. e202300116. PMID 37069799 DOI: 10.1002/cbic.202300116  0.706
2022 Page ACS, Scholz SO, Keenan KN, Spradlin JN, Belcher BP, Brittain SM, Tallarico JA, McKenna JM, Schirle M, Nomura DK, Toste FD. Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design. Chemical Science. 13: 3851-3856. PMID 35432890 DOI: 10.1039/d2sc00426g  0.767
2022 Henning NJ, Boike L, Spradlin JN, Ward CC, Liu G, Zhang E, Belcher BP, Brittain SM, Hesse MJ, Dovala D, McGregor LM, Valdez Misiolek R, Plasschaert LW, Rowlands DJ, Wang F, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nature Chemical Biology. PMID 35210618 DOI: 10.1038/s41589-022-00971-2  0.683
2022 Henning NJ, Manford AG, Spradlin JN, Brittain SM, Zhang E, McKenna JM, Tallarico JA, Schirle M, Rape M, Nomura DK. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications. Journal of the American Chemical Society. 144: 701-708. PMID 34994556 DOI: 10.1021/jacs.1c03980  0.822
2021 Fischer C, Vepřek NA, Peitsinis Z, Rühmann KP, Yang C, Spradlin JN, Dovala D, Nomura DK, Zhang Y, Trauner D. De novo Design of SARS-CoV-2 Main Protease Inhibitors. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 33: 458-463. PMID 35282568 DOI: 10.1055/a-1582-0243  0.611
2021 Biering SB, Van Dis E, Wehri E, Yamashiro LH, Nguyenla X, Dugast-Darzacq C, Graham TGW, Stroumza JR, Golovkine GR, Roberts AW, Fines DM, Spradlin JN, Ward CC, Bajaj T, Dovala D, et al. Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2. Acs Infectious Diseases. PMID 34129317 DOI: 10.1021/acsinfecdis.1c00017  0.754
2021 Spradlin JN, Zhang E, Nomura DK. Reimagining Druggability Using Chemoproteomic Platforms. Accounts of Chemical Research. PMID 33733731 DOI: 10.1021/acs.accounts.1c00065  0.734
2021 Luo M, Spradlin JN, Boike L, Tong B, Brittain SM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK. Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function. Cell Chemical Biology. PMID 33513350 DOI: 10.1016/j.chembiol.2021.01.005  0.77
2020 Tong B, Luo M, Xie Y, Spradlin JN, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK. Bardoxolone conjugation enables targeted protein degradation of BRD4. Scientific Reports. 10: 15543. PMID 32968148 DOI: 10.1038/s41598-020-72491-9  0.817
2020 Tong B, Spradlin JN, Novaes LFT, Zhang E, Hu X, Moeller M, Brittain SM, McGregor LM, McKenna JM, Tallarico JA, Schirle M, Maimone TJ, Nomura DK. A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL. Acs Chemical Biology. PMID 32568522 DOI: 10.1021/Acschembio.0C00348  0.681
2020 Coles GL, Cristea S, Webber JT, Levin RS, Moss SM, He A, Sangodkar J, Hwang YC, Arand J, Drainas AP, Mooney NA, Demeter J, Spradlin JN, Mauch B, Le V, et al. Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells. Cancer Cell. PMID 32531271 DOI: 10.1016/J.Ccell.2020.05.003  0.59
2019 Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, et al. Harnessing the anti-cancer natural product nimbolide for targeted protein degradation. Nature Chemical Biology. PMID 31209351 DOI: 10.1038/S41589-019-0304-8  0.805
2017 Grossman EA, Ward CC, Spradlin JN, Bateman LA, Huffman TR, Miyamoto DK, Kleinman JI, Nomura DK. Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products. Cell Chemical Biology. PMID 28919038 DOI: 10.1016/J.Chembiol.2017.08.013  0.747
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