Avner Schlessinger, Ph.D. - Publications

2007 Columbia University, New York, NY 
Bioinformatics Biology, General Biophysics, Molecular Biology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zur AA, Chien HC, Augustyn E, Flint A, Heeren N, Finke K, Hernandez C, Hansen L, Miller S, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA. LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates. Bioorganic & Medicinal Chemistry Letters. PMID 27624080 DOI: 10.1016/J.Bmcl.2016.09.001  0.72
2016 Klotz J, Porter BE, Colas C, Schlessinger A, Pajor AM. Mutations in the Na(+)/citrate cotransporter NaCT (SLC13A5) in pediatric patients with epilepsy and developmental delay. Molecular Medicine (Cambridge, Mass.). 22. PMID 27261973 DOI: 10.2119/Molmed.2016.00077  0.72
2016 Augustyn E, Finke K, Zur AA, Hansen L, Heeren N, Chien HC, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA. LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs. Bioorganic & Medicinal Chemistry Letters. PMID 27106710 DOI: 10.1016/J.Bmcl.2016.04.023  0.72
2016 Salvo E, Alabi S, Liu B, Schlessinger A, Bechhofer DH. Interaction of Bacillus subtilis Polynucleotide Phosphorylase and RNase Y: Structural Mapping and Effect on mRNA Turnover. The Journal of Biological Chemistry. PMID 26797123 DOI: 10.1074/jbc.M115.711044  0.72
2015 Colas C, Grewer C, Otte NJ, Gameiro A, Albers T, Singh K, Shere H, Bonomi M, Holst J, Schlessinger A. Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening. Plos Computational Biology. 11: e1004477. PMID 26444490 DOI: 10.1371/Journal.Pcbi.1004477  0.72
2015 Vicedo E, Schlessinger A, Rost B. Environmental Pressure May Change the Composition Protein Disorder in Prokaryotes. Plos One. 10: e0133990. PMID 26252577 DOI: 10.1371/Journal.Pone.0133990  0.72
2015 Kuechler A, Zink AM, Wieland T, Lüdecke HJ, Cremer K, Salviati L, Magini P, Najafi K, Zweier C, Czeschik JC, Aretz S, Endele S, Tamburrino F, Pinato C, Clementi M, ... ... Schlessinger A, et al. Loss-of-function variants of SETD5 cause intellectual disability and the core phenotype of microdeletion 3p25.3 syndrome. European Journal of Human Genetics : Ejhg. 23: 753-60. PMID 25138099 DOI: 10.1038/ejhg.2014.165  0.72
2014 Yachdav G, Kloppmann E, Kajan L, Hecht M, Goldberg T, Hamp T, Hönigschmid P, Schafferhans A, Roos M, Bernhofer M, Richter L, Ashkenazy H, Punta M, Schlessinger A, Bromberg Y, et al. PredictProtein--an open resource for online prediction of protein structural and functional features. Nucleic Acids Research. 42: W337-43. PMID 24799431 DOI: 10.1093/Nar/Gku366  0.72
2014 Feiglin A, Ashkenazi S, Schlessinger A, Rost B, Ofran Y. Co-expression and co-localization of hub proteins and their partners are encoded in protein sequence. Molecular Biosystems. 10: 787-94. PMID 24457447 DOI: 10.1039/C3Mb70411D  0.72
2013 Schlessinger A, Yee SW, Sali A, Giacomini KM. SLC classification: An update Clinical Pharmacology and Therapeutics. 94: 19-23. PMID 23778706 DOI: 10.1038/Clpt.2013.73  0.72
2013 Waight AB, Pedersen BP, Schlessinger A, Bonomi M, Chau BH, Roe-Zurz Z, Risenmay AJ, Sali A, Stroud RM. Structural basis for alternating access of a eukaryotic calcium/proton exchanger Nature. 499: 107-110. PMID 23685453 DOI: 10.1038/Nature12233  0.72
2013 Schlessinger A, Khuri N, Giacomini KM, Sali A. Molecular modeling and ligand docking for solute carrier (SLC) transporters. Current Topics in Medicinal Chemistry. 13: 843-56. PMID 23578028 DOI: 10.2174/1568026611313070007  0.72
2013 van Dam TJ, Townsend MJ, Turk M, Schlessinger A, Sali A, Field MC, Huynen MA. Evolution of modular intraflagellar transport from a coatomer-like progenitor. Proceedings of the National Academy of Sciences of the United States of America. 110: 6943-8. PMID 23569277 DOI: 10.1073/Pnas.1221011110  0.72
2013 Pedersen BP, Kumar H, Waight AB, Risenmay AJ, Roe-Zurz Z, Chau BH, Schlessinger A, Bonomi M, Harries W, Sali A, Johri AK, Stroud RM. Crystal structure of a eukaryotic phosphate transporter. Nature. 496: 533-6. PMID 23542591 DOI: 10.1038/Nature12042  0.72
2013 Geier EG, Schlessinger A, Fan H, Gable JE, Irwin JJ, Sali A, Giacomini KM. Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1. Proceedings of the National Academy of Sciences of the United States of America. 110: 5480-5. PMID 23509259 DOI: 10.1073/Pnas.1218165110  0.72
2013 Pieper U, Schlessinger A, Kloppmann E, Chang GA, Chou JJ, Dumont ME, Fox BG, Fromme P, Hendrickson WA, Malkowski MG, Rees DC, Stokes DL, Stowell MH, Wiener MC, Rost B, et al. Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nature Structural & Molecular Biology. 20: 135-8. PMID 23381628 DOI: 10.1038/Nsmb.2508  0.72
2012 Schlessinger A, Wittwer MB, Dahlin A, Khuri N, Bonomi M, Fan H, Giacomini KM, Sali A. High selectivity of the γ-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach. The Journal of Biological Chemistry. 287: 37745-56. PMID 22932902 DOI: 10.1074/Jbc.M112.388157  0.72
2011 Carlsson J, Coleman RG, Setola V, Irwin JJ, Fan H, Schlessinger A, Sali A, Roth BL, Shoichet BK. Ligand discovery from a dopamine D3 receptor homology model and crystal structure. Nature Chemical Biology. 7: 769-78. PMID 21926995 DOI: 10.1038/Nchembio.662  0.72
2011 Schlessinger A, Geier E, Fan H, Irwin JJ, Shoichet BK, Giacomini KM, Sali A. Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proceedings of the National Academy of Sciences of the United States of America. 108: 15810-5. PMID 21885739 DOI: 10.1073/Pnas.1106030108  0.72
2011 Schlessinger A, Schaefer C, Vicedo E, Schmidberger M, Punta M, Rost B. Protein disorder--a breakthrough invention of evolution? Current Opinion in Structural Biology. 21: 412-8. PMID 21514145 DOI: 10.1016/J.Sbi.2011.03.014  0.72
2011 Dokudovskaya S, Waharte F, Schlessinger A, Pieper U, Devos DP, Cristea IM, Williams R, Salamero J, Chait BT, Sali A, Field MC, Rout MP, Dargemont C. A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Molecular & Cellular Proteomics : McP. 10: M110.006478. PMID 21454883 DOI: 10.1074/Mcp.M110.006478  0.72
2011 Pieper U, Webb BM, Barkan DT, Schneidman-Duhovny D, Schlessinger A, Braberg H, Yang Z, Meng EC, Pettersen EF, Huang CC, Datta RS, Sampathkumar P, Madhusudhan MS, Sjölander K, Ferrin TE, et al. ModBase, a database of annotated comparative protein structure models, and associated resources. Nucleic Acids Research. 39: D465-74. PMID 21097780 DOI: 10.1093/nar/gkq1091  0.72
2010 Chen L, Pawlikowski B, Schlessinger A, More SS, Stryke D, Johns SJ, Portman MA, Chen E, Ferrin TE, Sali A, Giacomini KM. Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin. Pharmacogenetics and Genomics. 20: 687-99. PMID 20859243 DOI: 10.1097/Fpc.0B013E32833Fe789  0.72
2010 Chen L, Takizawa M, Chen E, Schlessinger A, Segenthelar J, Choi JH, Sali A, Kubo M, Nakamura S, Iwamoto Y, Iwasaki N, Giacomini KM. Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function. The Journal of Pharmacology and Experimental Therapeutics. 335: 42-50. PMID 20639304 DOI: 10.1124/Jpet.110.170159  0.72
2010 Lasker K, Phillips JL, Russel D, Velázquez-Muriel J, Schneidman-Duhovny D, Tjioe E, Webb B, Schlessinger A, Sali A. Integrative structure modeling of macromolecular assemblies from proteomics data. Molecular & Cellular Proteomics : McP. 9: 1689-702. PMID 20507923 DOI: 10.1074/Mcp.R110.000067  0.72
2010 Gruswitz F, Chaudhary S, Ho JD, Schlessinger A, Pezeshki B, Ho CM, Sali A, Westhoff CM, Stroud RM. Function of human Rh based on structure of RhCG at 2.1 A. Proceedings of the National Academy of Sciences of the United States of America. 107: 9638-43. PMID 20457942 DOI: 10.1073/Pnas.1003587107  0.72
2010 Schaefer C, Schlessinger A, Rost B. Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be. Bioinformatics (Oxford, England). 26: 625-31. PMID 20081223 DOI: 10.1093/bioinformatics/btq012  0.72
2010 Schlessinger A, Matsson P, Shima JE, Pieper U, Yee SW, Kelly L, Apeltsin L, Stroud RM, Ferrin TE, Giacomini KM, Sali A. Comparison of human solute carriers. Protein Science : a Publication of the Protein Society. 19: 412-28. PMID 20052679 DOI: 10.1002/Pro.320  0.72
2009 Schlessinger A, Punta M, Yachdav G, Kajan L, Rost B. Improved disorder prediction by combination of orthogonal approaches. Plos One. 4: e4433. PMID 19209228 DOI: 10.1371/Journal.Pone.0004433  0.72
2009 Galea CA, High AA, Obenauer JC, Mishra A, Park CG, Punta M, Schlessinger A, Ma J, Rost B, Slaughter CA, Kriwacki RW. Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome. Journal of Proteome Research. 8: 211-26. PMID 19067583 DOI: 10.1021/Pr800308V  0.32
2008 Ofran Y, Schlessinger A, Rost B. Automated identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes. Journal of Immunology (Baltimore, Md. : 1950). 181: 6230-5. PMID 18941213 DOI: 10.4049/Jimmunol.181.9.6230  0.72
2007 Schlessinger A, Punta M, Rost B. Natively unstructured regions in proteins identified from contact predictions. Bioinformatics (Oxford, England). 23: 2376-84. PMID 17709338 DOI: 10.1093/Bioinformatics/Btm349  0.72
2007 Schlessinger A, Liu J, Rost B. Natively unstructured loops differ from other loops. Plos Computational Biology. 3: e140. PMID 17658943 DOI: 10.1371/Journal.Pcbi.0030140  0.72
2007 Greenbaum JA, Andersen PH, Blythe M, Bui HH, Cachau RE, Crowe J, Davies M, Kolaskar AS, Lund O, Morrison S, Mumey B, Ofran Y, Pellequer JL, Pinilla C, Ponomarenko JV, ... ... Schlessinger A, et al. Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools. Journal of Molecular Recognition : Jmr. 20: 75-82. PMID 17205610 DOI: 10.1002/Jmr.815  0.72
2006 Schlessinger A, Yachdav G, Rost B. PROFbval: Predict flexible and rigid residues in proteins Bioinformatics. 22: 891-893. PMID 16455751 DOI: 10.1093/Bioinformatics/Btl032  0.72
2006 Schlessinger A, Ofran Y, Yachdav G, Rost B. Epitome: database of structure-inferred antigenic epitopes. Nucleic Acids Research. 34: D777-80. PMID 16381978 DOI: 10.1093/Nar/Gkj053  0.72
2005 Schlessinger A, Rost B. Protein flexibility and rigidity predicted from sequence. Proteins. 61: 115-26. PMID 16080156 DOI: 10.1002/Prot.20587  0.72
2003 Petrey D, Xiang Z, Tang CL, Xie L, Gimpelev M, Mitros T, Soto CS, Goldsmith-Fischman S, Kernytsky A, Schlessinger A, Koh IY, Alexov E, Honig B. Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling. Proteins. 53: 430-5. PMID 14579332 DOI: 10.1002/Prot.10550  0.72
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