Year |
Citation |
Score |
2023 |
Heydenreich FM, Marti-Solano M, Sandhu M, Kobilka BK, Bouvier M, Babu MM. Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.). 382: eadh1859. PMID 38127743 DOI: 10.1126/science.adh1859 |
0.422 |
|
2023 |
Marti-Solano M. A multi-dimensional view of context-dependent G protein-coupled receptor function. Biochemical Society Transactions. PMID 36688421 DOI: 10.1042/BST20210650 |
0.385 |
|
2021 |
Schmidt D, Scharf MM, Sydow D, Aßmann E, Martí-Solano M, Keul M, Volkamer A, Kolb P. Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening. Molecules (Basel, Switzerland). 26. PMID 33530327 DOI: 10.3390/molecules26030629 |
0.577 |
|
2020 |
Marti-Solano M, Crilly SE, Malinverni D, Munk C, Harris M, Pearce A, Quon T, Mackenzie AE, Wang X, Peng J, Tobin AB, Ladds G, Milligan G, Gloriam DE, Puthenveedu MA, et al. Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature. PMID 33149304 DOI: 10.1038/s41586-020-2888-2 |
0.319 |
|
2020 |
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, Aranda-García D, Ramírez-Anguita JM, Stepniewski TM, Worp N, Varela-Rial A, Morales-Pastor A, Medel-Lacruz B, Pándy-Szekeres G, Mayol E, Giorgino T, Carlsson J, Deupi X, ... ... Marti-Solano M, et al. Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome. Nature Methods. PMID 32704182 DOI: 10.1038/S41592-020-0928-3 |
0.502 |
|
2020 |
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, Aranda-García D, Ramírez-Anguita JM, Stepniewski TM, Worp N, Varela-Rial A, Morales-Pastor A, Medel-Lacruz B, Pándy-Szekeres G, Mayol E, Giorgino T, Carlsson J, Deupi X, ... ... Marti-Solano M, et al. GPCRmd uncovers the dynamics of the 3D-GPCRome. Nature Methods. PMID 32661425 DOI: 10.1038/S41592-020-0884-Y |
0.616 |
|
2019 |
Wright SC, Kozielewicz P, Kowalski-Jahn M, Petersen J, Bowin CF, Slodkowicz G, Marti-Solano M, Rodríguez D, Hot B, Okashah N, Strakova K, Valnohova J, Babu MM, Lambert NA, Carlsson J, et al. A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection. Nature Communications. 10: 667. PMID 30737406 DOI: 10.1038/S41467-019-08630-2 |
0.303 |
|
2018 |
Wootten D, Christopoulos A, Marti-Solano M, Babu MM, Sexton PM. Mechanisms of signalling and biased agonism in G protein-coupled receptors. Nature Reviews. Molecular Cell Biology. PMID 30104700 DOI: 10.1038/s41580-018-0049-3 |
0.49 |
|
2017 |
Hoppe A, Marti-Solano M, Drabek M, Bünemann M, Kolb P, Rinne A. The allosteric site regulates the voltage sensitivity of muscarinic receptors. Cellular Signalling. PMID 29056499 DOI: 10.1016/J.Cellsig.2017.10.011 |
0.588 |
|
2017 |
Iglesias A, Cimadevila M, la Fuente RA, Martí-Solano M, Cadavid MI, Castro M, Selent J, Loza MI, Brea J. Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization. European Journal of Pharmacology. PMID 28899696 DOI: 10.1016/J.Ejphar.2017.09.011 |
0.447 |
|
2017 |
Guixà-González R, Albasanz JL, Rodriguez-Espigares I, Pastor M, Sanz F, Martí-Solano M, Manna M, Martinez-Seara H, Hildebrand PW, Martín M, Selent J. Membrane cholesterol access into a G-protein-coupled receptor. Nature Communications. 8: 14505. PMID 28220900 DOI: 10.1038/Ncomms14505 |
0.426 |
|
2016 |
Martí-Solano M, Schmidt D, Kolb P, Selent J. Drugging specific conformational states of GPCRs: challenges and opportunities for computational chemistry. Drug Discovery Today. 21: 625-31. PMID 26821135 DOI: 10.1016/J.Drudis.2016.01.009 |
0.574 |
|
2015 |
Martí-Solano M, Iglesias A, de Fabritiis G, Sanz F, Brea J, Loza MI, Pastor M, Selent J. Detection of new biased agonists for the serotonin 5-HT2A receptor: modeling and experimental validation. Molecular Pharmacology. 87: 740-6. PMID 25661038 DOI: 10.1124/Mol.114.097022 |
0.476 |
|
2014 |
Martí-Solano M, Sanz F, Pastor M, Selent J. A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity. Plos One. 9: e109312. PMID 25313636 DOI: 10.1371/Journal.Pone.0109312 |
0.481 |
|
2014 |
Kaczor AA, Makarska-Bialokoz M, Selent J, de la Fuente RA, Martí-Solano M, Castro M. Application of BRET for studying G protein-coupled receptors. Mini Reviews in Medicinal Chemistry. 14: 411-25. PMID 24766382 DOI: 10.2174/1389557514666140428113708 |
0.474 |
|
2014 |
Selent J, Marti-Solano M, Rodríguez J, Atanes P, Brea J, Castro M, Sanz F, Loza MI, Pastor M. Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles. European Journal of Medicinal Chemistry. 77: 91-5. PMID 24631727 DOI: 10.1016/J.Ejmech.2014.02.058 |
0.507 |
|
2013 |
Martí-Solano M, Guixà-González R, Sanz F, Pastor M, Selent J. Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design. Current Pharmaceutical Design. 19: 5156-66. PMID 23621547 DOI: 10.2174/1381612811319280014 |
0.517 |
|
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