Wilhelm Stoffel - Publications

Affiliations: 
University of Cologne, Köln, Nordrhein-Westfalen, Germany 

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Year Citation  Score
2020 Stoffel W, Schmidt-Soltau I, Binczek E, Thomas A, Thevis M, Wegner I. Dietary ω3-and ω6-Polyunsaturated fatty acids reconstitute fertility of Juvenile and adult Fads2-Deficient mice. Molecular Metabolism. 36: 100974. PMID 32272092 DOI: 10.1016/J.Molmet.2020.100974  0.355
2019 Hammels I, Binczek E, Schmidt-Soltau I, Jenke B, Thomas A, Vogel M, Thevis M, Filipova D, Papadopoulos S, Stoffel W. Novel CB1-ligands maintain homeostasis of the endocannabinoid-system in ω3- and ω6-long chain-PUFA deficiency. Journal of Lipid Research. PMID 31167809 DOI: 10.1194/Jlr.M094664  0.344
2017 Stoffel W, Schmidt-Soltau I, Jenke B, Binczek E, Hammels I. Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier. The Journal of Investigative Dermatology. 137: 1424-1433. PMID 28259688 DOI: 10.1016/J.Jid.2017.02.973  0.306
2014 Stoffel W, Hammels I, Jenke B, Binczek E, Schmidt-Soltau I, Brodesser S, Odenthal M, Thevis M. Obesity resistance and deregulation of lipogenesis in Δ6-fatty acid desaturase (FADS2) deficiency. Embo Reports. 15: 110-20. PMID 24378641 DOI: 10.1002/Embr.201338041  0.381
2008 Stoffel W, Holz B, Jenke B, Binczek E, Günter RH, Kiss C, Karakesisoglou I, Thevis M, Weber AA, Arnhold S, Addicks K. Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids. The Embo Journal. 27: 2281-92. PMID 19172737 DOI: 10.1038/Emboj.2008.156  0.367
2007 Binczek E, Jenke B, Holz B, Günter RH, Thevis M, Stoffel W. Obesity resistance of the stearoyl-CoA desaturase-deficient (scd1-/-) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation. Biological Chemistry. 388: 405-18. PMID 17391062 DOI: 10.1515/Bc.2007.046  0.316
2002 Zumbansen M, Stoffel W. Neutral sphingomyelinase 1 deficiency in the mouse causes no lipid storage disease. Molecular and Cellular Biology. 22: 3633-8. PMID 11997500 DOI: 10.1128/Mcb.22.11.3633-3638.2002  0.348
2002 Janssen U, Stoffel W. Disruption of mitochondrial beta -oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse. The Journal of Biological Chemistry. 277: 19579-84. PMID 11916962 DOI: 10.1074/Jbc.M110993200  0.319
2002 Spörkel O, Uschkureit T, Büssow H, Stoffel W. Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and development. Glia. 37: 19-30. PMID 11746780 DOI: 10.1002/Glia.10014  0.349
2002 Bosio A, Binczek E, Haupt WF, Stoffel W. Composition and Biophysical Properties of Myelin Lipid Define the Neurological Defects in Galactocerebroside‐ and Sulfatide‐Deficient Mice Journal of Neurochemistry. 70: 308-315. PMID 9422376 DOI: 10.1046/J.1471-4159.1998.70010308.X  0.337
2001 Uschkureit T, Spörkel O, Büssow H, Stoffel W. Rumpshaker-like proteolipid protein (PLP) ratio in a mouse model with unperturbed structural and functional integrity of the myelin sheath and axons in the central nervous system. Glia. 35: 63-71. PMID 11424193 DOI: 10.1002/Glia.1071  0.318
2000 Simons M, Krämer EM, Thiele C, Stoffel W, Trotter J. Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains. The Journal of Cell Biology. 151: 143-54. PMID 11018060 DOI: 10.1083/Jcb.151.1.143  0.349
2000 Hofmann K, Tomiuk S, Wolff G, Stoffel W. Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase Proceedings of the National Academy of Sciences of the United States of America. 97: 5895-5900. PMID 10823942 DOI: 10.1073/Pnas.97.11.5895  0.343
2000 Nix M, Stoffel W. Perturbation of membrane microdomains reduces mitogenic signaling and increases susceptibility to apoptosis after T cell receptor stimulation. Cell Death & Differentiation. 7: 413-424. PMID 10800075 DOI: 10.1038/Sj.Cdd.4400666  0.316
2000 Tomiuk S, Zumbansen M, Stoffel W. Characterization and Subcellular Localization of Murine and Human Magnesium-dependent Neutral Sphingomyelinase Journal of Biological Chemistry. 275: 5710-5717. PMID 10681556 DOI: 10.1074/Jbc.275.8.5710  0.34
1999 Stoffel W. Functional analysis of acid and neutral sphingomyelinases in vitro and in vivo. Chemistry and Physics of Lipids. 102: 107-121. PMID 11001565 DOI: 10.1016/S0009-3084(99)00079-1  0.363
1998 Wahle S, Stoffel W. Cotranslational integration of myelin proteolipid protein (PLP) into the membrane of endoplasmic reticulum: Analysis of topology by glycosylation scanning and protease domain protection assay Glia. 24: 226-235. PMID 9728768 DOI: 10.1002/(Sici)1098-1136(199810)24:2<226::Aid-Glia7>3.0.Co;2-1  0.33
1998 Tomiuk S, Hofmann K, Nix M, Zumbansen M, Stoffel W. Cloned mammalian neutral sphingomyelinase: Functions in sphingolipid signaling? Proceedings of the National Academy of Sciences of the United States of America. 95: 3638-3643. PMID 9520418 DOI: 10.1073/Pnas.95.7.3638  0.313
1997 Stoffel W, Bosio A. Myelin glycolipids and their functions Current Opinion in Neurobiology. 7: 654-661. PMID 9384539 DOI: 10.1016/S0959-4388(97)80085-2  0.333
1997 Weiss B, Stoffel W. Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis. Febs Journal. 249: 239-247. PMID 9363775 DOI: 10.1111/J.1432-1033.1997.00239.X  0.328
1997 Kuemmel TA, Schroeder R, Stoffel W. Light and electron microscopic analysis of the central and peripheral nervous systems of acid sphingomyelinase-deficient mice resulting from gene targeting. Journal of Neuropathology and Experimental Neurology. 56: 171-179. PMID 9034371 DOI: 10.1097/00005072-199702000-00008  0.313
1996 Wahle S, Stoffel W. Membrane Topology of the High-affinity L-Glutamate Transporter (GLAST-1) of the Central Nervous System Journal of Cell Biology. 135: 1867-1877. PMID 8991097 DOI: 10.1083/Jcb.135.6.1867  0.306
1996 Bosio A, Binczek E, Stoffel W. Functional Breakdown of the Lipid Bilayer of the Myelin Membrane in Central and Peripheral Nervous System by Disrupted Galactocerebroside Synthesis Proceedings of the National Academy of Sciences of the United States of America. 93: 13280-13285. PMID 8917582 DOI: 10.1073/Pnas.93.23.13280  0.335
1996 Bosio A, Binczek E, Le Beau MM, Fernald AA, Stoffel W. The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26. Genomics. 34: 69-75. PMID 8661025 DOI: 10.1006/Geno.1996.0242  0.31
1996 Hoffmann MM, Stoffel W. Construction And Functional Characterization Of Recombinant Fusion Proteins Of Human Lipoprotein Lipase And Apolipoprotein Cii Febs Journal. 237: 545-552. PMID 8647097 DOI: 10.1111/J.1432-1033.1996.0545P.X  0.369
1995 Schulte S, Stoffel W. UDP galactose : ceramide galactosyltransferase and glutamate/aspartate transporter Copurification, separation and characterization of the two glycoproteins Febs Journal. 233: 947-953. PMID 8521863 DOI: 10.1111/J.1432-1033.1995.947_3.X  0.313
1995 Otterbach B, Stoffel W. Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease) Cell. 81: 1053-1061. PMID 7600574 DOI: 10.1016/S0092-8674(05)80010-8  0.317
1995 Conradt M, Stoffel W. Functional analysis of the high affinity, Na+-dependent glutamate transporter GLAST-1 by site-directed mutagenesis Journal of Biological Chemistry. 270: 25207-25212. PMID 7559657 DOI: 10.1074/Jbc.270.42.25207  0.315
1995 Müller‐Newen G, Janssen U, Stoffel W. Enoyl-CoA hydratase and isomerase form a superfamily with a common active-site glutamate residue. Febs Journal. 228: 68-73. DOI: 10.1111/J.1432-1033.1995.0068O.X  0.327
1994 Hofmann K, Düker M, Fink T, Lichter P, Stoffel W. Human neutral amino acid transporter ASCT1: Structure of the gene (SLC1A4) and localization to chromosome 2p13-p15 Genomics. 24: 20-26. PMID 7896285 DOI: 10.1006/Geno.1994.1577  0.309
1994 Janssen U, Fink T, Lichter P, Stoffel W. Human mitochondrial 3,2-trans-enoyl-CoA isomerase (DCI): gene structure and localization to chromosome 16p13.3. Genomics. 23: 223-228. PMID 7829074 DOI: 10.1006/Geno.1994.1480  0.314
1994 Weimbs T, Stoffel W. Topology of CNS myelin proteolipid protein: Evidence for the nonenzymatic glycosylation of extracytoplasmic domains in normal and diabetic animals Biochemistry. 33: 10408-10415. PMID 7520754 DOI: 10.1021/Bi00200A023  0.63
1993 Stoffel W, Düker M, Hofmann K. Molecular cloning and gene organization of the mouse mitochondrial 3,2-trans-enoyl-CoA isomerase Febs Letters. 333: 119-122. PMID 8224148 DOI: 10.1016/0014-5793(93)80387-A  0.335
1993 Schulte S, Stoffel W. Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression. Proceedings of the National Academy of Sciences of the United States of America. 90: 10265-10269. PMID 7694285 DOI: 10.1073/Pnas.90.21.10265  0.365
1993 Janz R, Stoffel W. Characterization of a brain-specific Sp1-like activity interacting with an unusual binding site within the myelin proteolipid protein promoter. Biological Chemistry Hoppe-Seyler. 374: 507-518. PMID 7692880 DOI: 10.1515/Bchm3.1993.374.7-12.507  0.307
1992 Stoffel W, Müller R, Binczek E, Hofmann K. Mouse apolipoprotein AI. cDNA-derived primary structure, gene organisation and complete nucleotide sequence. Biological Chemistry Hoppe-Seyler. 373: 187-194. PMID 1596360 DOI: 10.1515/Bchm3.1992.373.1.187  0.338
1992 Newrzella D, Stoffel W. Molecular cloning of the acid sphingomyelinase of the mouse and the organization and complete nucleotide sequence of the gene. Biological Chemistry Hoppe-Seyler. 373: 1233-1238. PMID 1292508 DOI: 10.1515/Bchm3.1992.373.2.1233  0.318
1992 Weimbs T, Stoffel W. Proteolipid protein (PLP) of CNS myelin: Positions of free, disulfide- bonded, and fatty acid thioester-linked cysteine residues and implications for the membrane topology of PLP Biochemistry. 31: 12289-12296. PMID 1281423 DOI: 10.1021/Bi00164A002  0.672
1992 Storck T, Schulte S, Hofmann K, Stoffel W. Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proceedings of the National Academy of Sciences of the United States of America. 89: 10955-10959. PMID 1279699 DOI: 10.1073/Pnas.89.22.10955  0.309
1991 Kurth J, Stoffel W. Human placental sphingomyelinase. Purification to homogeneity, antigenic properties and partial amino-acid sequences of the enzyme. Biological Chemistry Hoppe-Seyler. 372: 215-224. PMID 2054099 DOI: 10.1515/Bchm3.1991.372.1.215  0.331
1991 Müller-Newen G, Stoffel W. Mitochondrial 3-2trans-Enoyl-CoA isomerase. Purification, cloning, expression, and mitochondrial import of the key enzyme of unsaturated fatty acid beta-oxidation. Biological Chemistry Hoppe-Seyler. 372: 613-624. PMID 1958319 DOI: 10.1515/Bchm3.1991.372.2.613  0.361
1991 Bruhn H, Stoffel W. An approach to the functional analysis of lecithin-cholesterol acyltransferase. Activation by recombinant normal and mutagenized apolipoprotein AI. Biological Chemistry Hoppe-Seyler. 372: 225-234. PMID 1905134 DOI: 10.1515/Bchm3.1991.372.1.225  0.315
1991 Schliess F, Stoffel W. Evolution of the myelin integral membrane proteins of the central nervous system. Biological Chemistry Hoppe-Seyler. 372: 865-874. PMID 1722981 DOI: 10.1515/Bchm3.1991.372.2.865  0.358
1990 Euler-Bertram S, Stoffel W. Purification and characterization of bovine liver 3-cis-2-trans-enoyl-CoA isomerase. Biological Chemistry Hoppe-Seyler. 371: 603-610. PMID 2222859 DOI: 10.1515/Bchm3.1990.371.2.603  0.318
1990 Weimbs T, Dick T, Stoffel W, Boltshauser E. A point mutation at the X-chromosomal proteolipid protein locus in Pelizaeus-Merzbacher disease leads to disruption of myelinogenesis. Biological Chemistry Hoppe-Seyler. 371: 1175-1183. PMID 1708672 DOI: 10.1515/Bchm3.1990.371.2.1175  0.646
1990 Kurth J, Stoffel W. A facile method for the isolation and preparation of proteins and peptides for sequence analysis in the picomolar range. Biological Chemistry Hoppe-Seyler. 371: 675-686. DOI: 10.1515/Bchm3.1990.371.2.675  0.309
1989 Stoffel W, Subkowski T, Jander S. Topology of proteolipid protein in the myelin membrane of central nervous system. A study using antipeptide antibodies. Biological Chemistry Hoppe-Seyler. 370: 165-176. PMID 2468346 DOI: 10.1515/Bchm3.1989.370.1.165  0.335
1989 Boison D, Stoffel W. Myelin-deficient rat: a point mutation in exon III (A----C, Thr75----Pro) of the myelin proteolipid protein causes dysmyelination and oligodendrocyte death. The Embo Journal. 8: 3295-3302. DOI: 10.1002/J.1460-2075.1989.Tb08490.X  0.315
1988 Stoffel W, Binczek E. Structural requirements of human preproapolipoprotein AI for translocation and processing studied by site-directed mutagenesis in vitro. Biological Chemistry Hoppe-Seyler. 369: 1055-1064. PMID 3228490 DOI: 10.1515/Bchm3.1988.369.2.1055  0.336
1988 Holtfreter C, Stoffel W. Expression of normal and mutagenized apolipoprotein CII in procaryotic cells. Structure-function relationship. Biological Chemistry Hoppe-Seyler. 369: 1045-1054. PMID 3067732 DOI: 10.1515/Bchm3.1988.369.2.1045  0.338
1988 Haase A, Stoffel W. Expression of the human serum apolipoprotein AI and AII genes in Xenopus laevis oocytes. Lipid-associated secretion of gene products. Biological Chemistry Hoppe-Seyler. 369: 585-594. PMID 2852015 DOI: 10.1515/Bchm3.1988.369.2.585  0.3
1986 Diehl H, Schaich M, Budzinski R, Stoffel W. Individual exons encode the integral membrane domains of human myelin proteolipid protein. Proceedings of the National Academy of Sciences of the United States of America. 83: 9807-9811. PMID 3467339 DOI: 10.1073/Pnas.83.24.9807  0.362
1986 Pfitzner R, Wagener R, Stoffel W. Isolation, expression and characterization of a human apolipoprotein B 100-specific cDNA clone. Biological Chemistry Hoppe-Seyler. 367: 1077-1084. PMID 3024665 DOI: 10.1515/Bchm3.1986.367.2.1077  0.316
1986 Schaich M, Budzinski R, Stoffel W. Cloned proteolipid protein and myelin basic protein cDNA. Transcription of the two genes during myelination. Biological Chemistry Hoppe-Seyler. 367: 825-834. PMID 2429678 DOI: 10.1515/Bchm3.1986.367.2.825  0.331
1985 Stoffel W, Giersiefen H, Hillen H, Schroeder W, Tunggal B. Amino-acid sequence of human and bovine brain myelin proteolipid protein (lipophilin) is completely conserved. Biological Chemistry Hoppe-Seyler. 366: 627-636. PMID 4041237 DOI: 10.1515/Bchm3.1985.366.2.627  0.353
1985 Stoffel W, Niedel B. Processing of proapolipoprotein AI requires specific conformation. Biological Chemistry Hoppe-Seyler. 366: 181-187. PMID 3921042 DOI: 10.1515/Bchm3.1985.366.1.181  0.333
1985 Stoffel W, Blau R, Burk M. Synthesis and processing of human serum apolipoprotein AII in vitro and in Hep G2 cells. Biological Chemistry Hoppe-Seyler. 366: 173-180. PMID 2985098 DOI: 10.1515/Bchm3.1985.366.1.173  0.354
1984 Stoffel W, Hillen H, Giersiefen H. Structure and molecular arrangement of proteolipid protein of central nervous system myelin Proceedings of the National Academy of Sciences of the United States of America. 81: 5012-5016. PMID 6206491 DOI: 10.1073/Pnas.81.16.5012  0.364
1983 Stoffel W, Hillen H, Schröder W, Deutzmann R. The primary structure of bovine brain myelin lipophilin (proteolipid apoprotein). Biological Chemistry. 364: 1455-1466. PMID 6642431 DOI: 10.1515/Bchm2.1983.364.2.1455  0.384
1983 Dang QQ, Stoffel W. A new synthesis of bis(diacylglycero)phosphate. Chemistry and Physics of Lipids. 33: 33-40. PMID 6627524 DOI: 10.1016/0009-3084(83)90005-1  0.304
1983 Stoffel W, Knyrim K, Bode C. A serum proteinase converts proapolipoprotein AI secreted by rat hepatocytes to the mature apolipoprotein. Biological Chemistry. 364: 1631-1640. PMID 6420309 DOI: 10.1515/Bchm2.1983.364.2.1631  0.322
1983 Stoffel W, Krüger E, Deutzmann R. Cell-free translation of human liver apolipoprotein AI and AII mRNA. Processing of primary translation products. Biological Chemistry. 364: 227-238. PMID 6407957 DOI: 10.1515/Bchm2.1983.364.1.227  0.347
1982 Stoffel W, Hillen H, Schröder W, Deutzmann R. Lipophilin (proteolipid apoprotein) of brain white matter. Purification and amino acid sequence studies of the four tryptophan fragments. Biological Chemistry. 363: 1397-1408. PMID 7173828 DOI: 10.1515/Bchm2.1982.363.2.1397  0.368
1982 Stoffel W, Schröder W, Hillen H, Deutzmann R. Analysis of the primary structure of the strongly hydrophobic brain myelin proteolipid apoprotein (lipophilin). Isolation and amino acid sequence determination of proteolytic fragments. Biological Chemistry. 363: 1117-1132. PMID 7141416 DOI: 10.1515/Bchm2.1982.363.2.1117  0.364
1982 Stoffel W, Salm K, Müller M. Syntheses of phosphatidylcholines, sphingomyelins and cholesterol substituted with azido fatty acids. Photocrosslinking with nearest neighbouring lipids in liposomes chemical and mass spectroscopic proof. Biological Chemistry. 363: 1-18. PMID 7061040 DOI: 10.1515/Bchm2.1982.363.1.1  0.352
1982 Stoffel W, Metz P. Chemical studies on the structure of human serum high-density lipoprotein (HDL). Photochemical crosslinking of azido-labelled lipids in HDL. Biological Chemistry. 363: 19-32. PMID 7037591 DOI: 10.1515/Bchm2.1982.363.1.19  0.34
1981 Stoffel W, Blobel G, Walter P. Synthesis in vitro and translocation of apolipoprotein AI across microsomal vesicles. European Journal of Biochemistry / Febs. 120: 519-22. PMID 6174327 DOI: 10.1111/J.1432-1033.1981.Tb05730.X  0.352
1980 Stoffel W, Krüger E, Melzner I. Studies on the biosynthesis of ceramide. Does the reversed ceramidase reaction yield ceramides Biological Chemistry. 361: 773-780. PMID 7429425 DOI: 10.1515/Bchm2.1980.361.1.773  0.323
1980 Utsumi H, Tunggal BD, Stoffel W. Carbon-13 nuclear magnetic resonance studies on the interaction of glycophorin with lecithin in reconstituted vesicles. Biochemistry. 19: 2385-2390. PMID 7387980 DOI: 10.1021/Bi00552A016  0.302
1980 Stoffel W, Melzner I. Studies in vitro on the biosynthesis of ceramide and sphingomyelin. A reevaluation of proposed pathways. Biological Chemistry. 361: 755-772. PMID 6253377 DOI: 10.1515/Bchm2.1980.361.1.755  0.326
1979 Heller RA, Klotzbücher R, Stoffel W. Interactions of a photosensitive analog of cholesterol with hydroxymethylglutaryl-CoA reductase (NADPH) and acyl-CoA:cholesterol acyltransferase Proceedings of the National Academy of Sciences of the United States of America. 76: 1721-1725. PMID 287013 DOI: 10.1073/Pnas.76.4.1721  0.351
1979 Stoffel W, Preissner K. Surface localization of apolipoprotein AII in lipoprotein-complexes. Biological Chemistry. 360: 685-690. PMID 223955 DOI: 10.1515/Bchm2.1979.360.1.685  0.314
1979 Stoffel W, Salm K, Tunggal B. 13C-NMR spectroscopy of human serum high density lipoprotein enriched with labelled phospholipids. Biological Chemistry. 360: 523-528. PMID 220173 DOI: 10.1515/Bchm2.1979.360.1.523  0.33
1979 Stoffel W, Metz P. Covalent cross-linking of photosensitive phospholipids to human serum high density apolipoproteins (apoHDL). Biological Chemistry. 360: 197-206. PMID 217815 DOI: 10.1515/Bchm2.1979.360.1.197  0.301
1978 Stoffel W, Grol M. Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase (dodecenoyl-CoA delta-isomerase) from rat liver mitochondria. Hoppe-Seyler's Zeitschrift FüR Physiologische Chemie. 359: 1777-82. PMID 738702 DOI: 10.1515/Bchm2.1978.359.2.1777  0.335
1977 Stoffel W, Därr W, Salm K. Chemical proof of lipid-protein interactions by crosslinking photosensitive lipids to apoproteins. Intermolecular cross-linkage between high-density apolipoprotein A-I and lecithins and sphingomyelins. Biological Chemistry. 358: 453-462. PMID 193772 DOI: 10.1515/Bchm2.1977.358.1.453  0.356
1977 Stoffel W, Därr W, Salm K. Lipid-protein interactions between human apolipoprotein A-I and defined sphingomyelin species. A 13C-NMR spectroscopic study. Biological Chemistry. 358: 1-12. PMID 190104 DOI: 10.1515/Bchm2.1977.358.1.1  0.339
1976 Stoffel W, Michaelis G. Chemical syntheses of novel fluorescent-labelled fatty acids, phosphatidylcholines and cholesterol esters. Biological Chemistry. 357: 7-19. PMID 1248800 DOI: 10.1515/Bchm2.1976.357.1.7  0.331
1976 Stoffel W, Michaelis G. Biosynthetic labelling of membrane lipids of eukaryotic cells in tissue culture by a novel type of fluorescent fatty acids. Biological Chemistry. 357: 925-936. PMID 1033138 DOI: 10.1515/Bchm2.1976.357.2.925  0.383
1976 Stoffel W, Salm K, Körkemeier U. Biosynthetic Incorporation of Fatty Acids with Photosensitive Groups into Membrane Lipids of Cells in Tissue Culture Biological Chemistry. 357: 917-924. PMID 1033137 DOI: 10.1515/Bchm2.1976.357.2.917  0.377
1976 Stoffel W, Michaelis G. Lipid-lipid and lipid-protein interactions as studied with a novel type of fluorescent fatty acid and phospholipid probes. Biological Chemistry. 357: 21-33. PMID 765259 DOI: 10.1515/Bchm2.1976.357.1.21  0.356
1976 Stoffel W, Bister K, Schreiber C, Tunggal B. 13C-NMR studies of the membrane structure of enveloped virions (vesicular stomatitis virus). Biological Chemistry. 357: 905-915. PMID 186376 DOI: 10.1515/Bchm2.1976.357.2.905  0.358
1975 Stoffel W, Dittmar K, Wilmes R. Sphingolipid metabolism in Bacteroideaceae. Biological Chemistry. 356: 715-726. PMID 1181270 DOI: 10.1515/Bchm2.1975.356.S1.715  0.376
1975 Stoffel W, Anderson R, Stahl J. Studies on the asymmetric arrangement of membrane-lipid-enveloped virions as a model system. Biological Chemistry. 356: 1123-1130. PMID 172423 DOI: 10.1515/Bchm2.1975.356.2.1123  0.345
1975 Stoffel W, Bister K. Carbon-13 nuclear magnetic resonance studies on the lipid organization in enveloped virions (vesicular stomatitis virus) Biochemistry. 14: 2841-2847. PMID 167809 DOI: 10.1021/Bi00684A008  0.357
1974 Stoffel W, Zierenberg O, Tunggal B, Schreiber E. 13C nuclear magnetic resonance spectroscopic evidence for hydrophobic lipid-protein interactions in human high density lipoproteins. Proceedings of the National Academy of Sciences of the United States of America. 71: 3696-3700. PMID 4372633 DOI: 10.1073/Pnas.71.9.3696  0.316
1973 Henning R, Plattner H, Stoffel W. Nature and localization of acidic groups on lysosomal membranes Bba - Biomembranes. 330: 61-75. PMID 4128464 DOI: 10.1016/0005-2736(73)90284-8  0.329
1970 Henning R, Kaulen HD, Stoffel W. Biochemical Analysis of the Pinocytotic Process, I: Isolation and Chemical Composition of the Lysosomal and the Plasma Membrane of the Rat Liver Cell Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 351: 1191-1199. PMID 5479418 DOI: 10.1515/Bchm2.1970.351.2.1191  0.344
1970 Overath P, Schairer HU, Stoffel W. Correlation of In Vivo and In Vitro Phase Transitions of Membrane Lipids in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 67: 606-612. PMID 4943175 DOI: 10.1073/Pnas.67.2.606  0.351
1970 Kaulen HD, Henning R, Stoffel W. Biochemical Analysis of the Pinocytotic Process, II1: Comparison of some Enzymes of the Lysosomal and the Plasma Membrane of the Rat Liver Cell Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 351: 1555-1563. PMID 4321590 DOI: 10.1515/Bchm2.1970.351.2.1555  0.301
1968 Stoffel W, Henning R. Studies on the Metabolism of [l-3H]erythro-DL-Sphingosine ([l-3H]4t-sphingenine) during the Myelination Period of the Rat Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 349: 1400-1404. PMID 5699466 DOI: 10.1515/Bchm2.1968.349.2.1400  0.32
1967 Stoffel W, Lekim D, Sticht G. Metabolism of sphingosine bases. IV. 2-Amino-1-hydroxyoctadecane-3-one (3-oxodihydrosphingosine), the common intermediate in the biosynthesis of dihydrospingosine and sphingosine and in the degradation of dihydrosphingosine. Biological Chemistry. 348: 1570-1574. PMID 5586903 DOI: 10.1515/Bchm2.1967.348.1.1570  0.314
1967 Overath P, Raufuss E, Stoffel W, Ecker W. The induction of the enzymes of fatty acid degradation in Escherichiacoli Biochemical and Biophysical Research Communications. 29: 28-33. PMID 4861587 DOI: 10.1016/0006-291X(67)90535-9  0.323
1966 Stoffel W, Schiefer H, Wolf GD. Studies on the biosynthesis of membrane phospholipids. Acylation of lysolecithins with polyenoic fatty acids Biological Chemistry. 347: 102-117. DOI: 10.1515/Bchm2.1966.347.1.102  0.36
1966 Stoffel W, Schiefer H. [Metabolism of unsaturated fatty acids, 7. Studies on the formation of cis-olefin bonds in polyenic fatty acids]. Biological Chemistry. 345: 41-51. DOI: 10.1515/Bchm2.1966.345.1.41  0.33
1965 Stoffel W, Wiese H. [The Biosynthesis Of Oleic-, Linoleic- And Gamma-Linolenic Acid In Phycomyces Blakesleeanus]. Biological Chemistry. 340: 148-156. PMID 14309053 DOI: 10.1515/Bchm2.1965.340.1-2.148  0.302
1964 Stoffel W, Caesar H, Ditzer R. [The metabolism of unsaturated fatty acids. IV. On the beta-oxidation of mono-and polyene-fatty acids. Chemical syntheses of intermediary products]. Biological Chemistry. 339: 182-193. DOI: 10.1515/Bchm2.1964.339.1.182  0.318
1964 Stoffel W, Ditzer R, Caesar H. [The metabolism of unsaturated fatty acid. 3. On the beta-oxidation of mono- and polyene-fatty acids. The mechanism of the enzymatic reaction on delta-3-cis-enoyl-CoA compounds]. Biological Chemistry. 339: 167-181. DOI: 10.1515/Bchm2.1964.339.1.167  0.316
1963 Stoffel W. The Metabolism Of Unsaturated Fatty Acids. I. On The Biosynthesis Of Highly Unsaturated Fatty Acids Biological Chemistry. 333: 71-88. PMID 14058289 DOI: 10.1515/Bchm2.1963.333.1.71  0.34
1961 Stoffel W. Biosynthesis of polyenoic fatty acids Biochemical and Biophysical Research Communications. 6: 270-273. PMID 13917333 DOI: 10.1016/0006-291X(61)90376-X  0.325
1959 Ahrens E, Hirsch J, Insull W, Stoffel W, Peterson M, Farquhar J, Miller T, Thomasson HJ. The effect on human serum-lipids of a dietary fat, highly unsaturated, but poor in essential fatty acids. The Lancet. 273: 115-119. PMID 13621653 DOI: 10.1016/S0140-6736(59)90002-9  0.33
Low-probability matches (unlikely to be authored by this person)
1983 Stoffel W, Bode C, Knyrim K. Serum apolipoprotein AI synthesis in rat hepatocytes and its secretion as proform. Biological Chemistry. 364: 439-446. PMID 6407959 DOI: 10.1515/Bchm2.1983.364.1.439  0.298
1997 Stoffel W, Boison D, Büssow H. Functional analysis in vivo of the double mutant mouse deficient in both proteolipid protein (PLP) and myelin basic protein (MBP) in the central nervous system Cell and Tissue Research. 289: 195-206. PMID 9211822 DOI: 10.1007/S004410050866  0.297
1970 Stoffel W. Studies on the biosynthesis and degradation of sphingosine bases. Chemistry and Physics of Lipids. 5: 139-158. PMID 4394486 DOI: 10.1016/0009-3084(70)90014-9  0.296
2005 Stoffel W, Jenke B, Blöck B, Zumbansen M, Koebke J. Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development. Proceedings of the National Academy of Sciences of the United States of America. 102: 4554-9. PMID 15764706 DOI: 10.1073/Pnas.0406380102  0.296
1971 Henning R, Kaulen HD, Stoffel W. Biochemical Analysis of the Pinocytotic Process, III 1,2: Subcellular Distribution and Metabolic Effects of [3H]Triton Wr-1339 Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 352: 1347-1358. PMID 4331492 DOI: 10.1515/Bchm2.1971.352.2.1347  0.296
1978 Stoffel W, Klotzbücher R. Inhibition of cholesterol synthesis in cultured cells by 25-azidonorcholesterol. Biological Chemistry. 359: 199-209. PMID 649054 DOI: 10.1515/Bchm.1978.359.1.199  0.296
1994 Boison D, Stoffel W. Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 91: 11709-11713. PMID 7526402 DOI: 10.1073/Pnas.91.24.11709  0.295
2012 van Weeghel M, te Brinke H, van Lenthe H, Kulik W, Minkler PE, Stoll MS, Sass JO, Janssen U, Stoffel W, Schwab KO, Wanders RJ, Hoppel CL, Houten SM. Functional redundancy of mitochondrial enoyl-CoA isomerases in the oxidation of unsaturated fatty acids. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4316-26. PMID 22782973 DOI: 10.1096/Fj.12-206326  0.295
1995 Boison D, Bussow H, D'Urso D, Muller H, Stoffel W. Adhesive properties of proteolipid protein are responsible for the compaction of CNS myelin sheaths The Journal of Neuroscience. 15: 5502-5513. DOI: 10.1523/Jneurosci.15-08-05502.1995  0.294
1992 Hofmann K, Stoffel W. PROFILEGRAPH: an interactive graphical tool for protein sequence analysis. Bioinformatics. 8: 331-337. PMID 1498688 DOI: 10.1093/Bioinformatics/8.4.331  0.293
2016 Stoffel W, Hammels I, Jenke B, Binczek E, Schmidt-Soltau I, Brodesser S, Schauss A, Etich J, Heilig J, Zaucke F. Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition. Cell Death & Disease. 7: e2488. PMID 27882938 DOI: 10.1038/Cddis.2016.385  0.293
1978 Stoffel W, Schreiber C, Scheefers H. Lipids with photosensitive groups as chemical probes for the structural analysis of biological membranes. On the localization of the G- and M-protein of vesicular stomatitis virus. Biological Chemistry. 359: 923-932. PMID 213365 DOI: 10.1515/Bchm2.1978.359.2.923  0.291
1990 Stoffel W. The Myelin Membrane of the Central Nervous System—Essential Macromolecular Structure and Function Angewandte Chemie. 29: 958-976. DOI: 10.1002/Anie.199009581  0.291
1972 Stoffel W, Zierenberg O, Tunggal BD. 13 C-nuclear magnetic resonance spectroscopic studies on saturated, mono-, di- and polyunsaturated fatty acids, phospho- and sphingolipids. Biological Chemistry. 353: 1962-1969. PMID 4650175 DOI: 10.1515/Bchm2.1972.353.2.1962  0.29
1996 Bosio A, Binczek E, Stoffel W. Molecular cloning and characterization of the mouse CGT gene encoding UDP-galactose ceramide-galactosyltransferase (cerebroside synthetase) Genomics. 35: 223-226. PMID 8661124 DOI: 10.1006/Geno.1996.0342  0.29
1996 Rosenbluth J, Stoffel W, Schiff R. Myelin structure in proteolipid protein (PLP)-null mouse spinal cord. The Journal of Comparative Neurology. 371: 336-44. PMID 8835737 DOI: 10.1002/(Sici)1096-9861(19960722)371:2<336::Aid-Cne12>3.0.Co;2-Q  0.287
1996 Newrzella D, Stoffel W. Functional Analysis Of The Glycosylation Of Murine Acid Sphingomyelinase Journal of Biological Chemistry. 271: 32089-32095. PMID 8943261 DOI: 10.1074/Jbc.271.50.32089  0.287
1997 Janßen U, Davis EM, Le Beau MM, Stoffel W. Human mitochondrial enoyl-CoA hydratase gene (ECHS1): Structural organization and assignment to chromosome 10q26.2-q26.3 Genomics. 40: 470-475. PMID 9073515 DOI: 10.1006/Geno.1996.4597  0.286
1993 Otterbach B, Stoffel W, Ramaekers V. A novel mutation in the proteolipid protein gene leading to Pelizaeus-Merzbacher disease. Biological Chemistry Hoppe-Seyler. 374: 75-83. PMID 7679906 DOI: 10.1515/Bchm3.1993.374.1-6.75  0.285
1982 Stoffel W, Hillen H, Schroeder W, Deutzmann R. Primary structure of the C-terminal cyanogen bromide fragments II, III and IV from bovine brain proteolipid-apoprotein. Biological Chemistry. 363: 855-864. PMID 7118077 DOI: 10.1515/Bchm2.1982.363.2.855  0.284
1972 LeKim D, Betzing H, Stoffel W. Incorporation of complete phospholipid molecules in cellular membranes of rat liver after uptake from blood serum. Biological Chemistry. 353: 949-964. PMID 5052950 DOI: 10.1515/Bchm2.1972.353.1.949  0.283
1973 Stoffel W. Sphingosine metabolism and its link to phospholipid biosynthesis. Molecular and Cellular Biochemistry. 1: 147-155. PMID 4585089 DOI: 10.1007/Bf01659326  0.283
1974 Stoffel W, Zirenberg O, Tunggal BD, Schreiber E. 13-C nuclear magnetic resonance spectroscopic studies on lipid-protein interactions in human high-density lipoprotein (HDL). A model of the HDL particle. Biological Chemistry. 355: 1381-1390. PMID 4376790 DOI: 10.1515/Bchm2.1974.355.2.1381  0.282
1968 Stoffel W, Lekim D, Sticht G. Metabolism of Sphingosine Bases, VIII. Distribution, Isolation and Properties of D-3-Oxosphinganine Reductase. Stereospecificity of the NADPH-dependent Reduction Reaction of 3-Oxodihydrosphingosine(2-Amino-1-hydroxyoctadecane-3-one) Biological Chemistry. 349: 1637-1644. PMID 4387676 DOI: 10.1515/Bchm2.1968.349.2.1637  0.278
1989 Streicher R, Stoffel W. The organization of the human myelin basic protein gene. Comparison with the mouse gene. Biological Chemistry Hoppe-Seyler. 370: 503-510. PMID 2472816 DOI: 10.1515/Bchm3.1989.370.1.503  0.278
1978 Stoffel W, Salm K, Langer M. A new method for the exchange of lipid classes of human serum high density lipoprotein. Biological Chemistry. 359: 1385-1394. PMID 214385 DOI: 10.1515/Bchm2.1978.359.2.1385  0.277
1959 Stoffel W, Chu F, Ahrens EH. Analysis of Long-Chain Fatty Acids by Gas-Liquid Chromatography Analytical Chemistry. 31: 307-308. DOI: 10.1021/Ac60146A047  0.277
1974 Stoffel W, Tunggal BD, Zierenberg O, Schreiber E, Binczek E. 13-C nuclear magnetic resonance studies of lipid interactions in single- and multi-component lipid vesicles. Biological Chemistry. 355: 1367-1380. PMID 4477757 DOI: 10.1515/Bchm2.1974.355.2.1367  0.277
2019 Stoffel W, Hammels I, Jenke B, Schmidt-Soltau I, Niehoff A. Neutral Sphingomyelinase 2 (SMPD3)-Deficiency in Mice Causes Chondrodysplasia with Unimpaired Skeletal Mineralization. The American Journal of Pathology. PMID 31199918 DOI: 10.1016/J.Ajpath.2019.05.008  0.277
1997 Kuemmel TA, Thiele J, Schroeder R, Stoffel W. Pathology of Visceral Organs and Bone Marrow in an Acid Sphingomyelinase Deficient Knock-Out Mouse Line, Mimicking Human Niemann-Pick Disease Type A: A Light and Electron Microscopic Study Pathology Research and Practice. 193: 663-671. PMID 9505258 DOI: 10.1016/S0344-0338(97)80025-8  0.277
1987 Wagener R, Pfitzner R, Stoffel W. Studies on the organization of the human apolipoprotein B 100 gene. Biological Chemistry Hoppe-Seyler. 368: 419-426. PMID 2886136 DOI: 10.1515/Bchm3.1987.368.1.419  0.276
1990 Tunggal B, Hofmann K, Stoffel W. In vivo 13C nuclear magnetic resonance investigations of choline metabolism in rabbit brain. Magnetic Resonance in Medicine. 13: 90-102. PMID 2319938 DOI: 10.1002/Mrm.1910130110  0.276
1974 Stoffel W, Heimann G. The action of lysosomal lipolytic enzymes on alkyl ether-containing phospholipids. Biological Chemistry. 355: 651-659. PMID 4435744 DOI: 10.1515/Bchm2.1974.355.1.651  0.276
1970 Stoffel W, Assmann G, Binczek E. Metabolism of sphingosine bases. 13. Enzymatic synthesis of 1-phosphate esters of 4t-sphingenine (sphingosine), sphinganine (dihydrosphingosine), 4-hydroxysphinganine (phytosphingosine) and 3-dehydrosphinganine by erythrocytes. Biological Chemistry. 351: 635-642. PMID 4315749 DOI: 10.1515/Bchm2.1970.351.1.635  0.275
1979 Stoffel W, Metz P, Heller R. Covalent binding of photosensitive 1-(12-azido-[9,10(-3)H2]oleoyl)glycero-3-phosphocholine (lysolecithin) to human serum high density apolipoproteins. Biological Chemistry. 360: 1319-1326. PMID 229069 DOI: 10.1515/Bchm2.1979.360.2.1319  0.275
1973 Stoffel W. Chemistry and biochemistry of sphingosine bases. Chemistry and Physics of Lipids. 11: 318-334. PMID 4772653 DOI: 10.1016/0009-3084(73)90068-6  0.274
1974 Stoffel W, Grol M. Chemistry and biochemistry of 1-desoxysphinganine 1-phosphonate (dihydrosphingosine-1-phosphonate). Chemistry and Physics of Lipids. 13: 372-88. PMID 4452217 DOI: 10.1016/0009-3084(74)90011-5  0.274
1997 Conradt M, Stoffel W. Inhibition of the high-affinity brain glutamate transporter GLAST-1 via direct phosphorylation Journal of Neurochemistry. 68: 1244-1251. PMID 9048771 DOI: 10.1046/J.1471-4159.1997.68031244.X  0.274
1972 Henning R, Stoffel W. Ubiquinone in the Lysosomal Membrane Fraction of Rat Liver Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 353: 75-78. PMID 4335783 DOI: 10.1515/Bchm2.1972.353.1.75  0.273
1995 Conradt M, Storck T, Stoffel W. Localization of N‐Glycosylation Sites and Functional Role of the Carbohydrate Units of GLAST‐1, a Cloned Rat Brain l‐glutamate/l‐aspartate Transporter Febs Journal. 229: 682-687. DOI: 10.1111/J.1432-1033.1995.0682J.X  0.272
1996 Stoffel W, Sasse J, Düker M, Müller R, Hofmann K, Fink T, Lichter P. Human high affinity, Na(+)-dependent L-glutamate/L-aspartate transporter GLAST-1 (EAAT-1): gene structure and localization to chromosome 5p11-p12. Febs Letters. 386: 189-93. PMID 8647279 DOI: 10.1016/0014-5793(96)00424-3  0.271
1998 Bosio A, Büssow H, Adam J, Stoffel W. Galactosphingolipids and axono-glial interaction in myelin of the central nervous system Cell and Tissue Research. 292: 199-210. PMID 9560463 DOI: 10.1007/S004410051051  0.271
2018 Stoffel W, Jenke B, Schmidt-Soltau I, Binczek E, Brodesser S, Hammels I. SMPD3 deficiency perturbs neuronal proteostasis and causes progressive cognitive impairment. Cell Death & Disease. 9: 507. PMID 29725009 DOI: 10.1038/S41419-018-0560-7  0.27
1997 Peghini P, Janzen J, Stoffel W. Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration. The Embo Journal. 16: 3822-32. PMID 9233792 DOI: 10.1093/Emboj/16.13.3822  0.267
1968 Stoffel W, Sticht G, Lekim D. Metabolism of sphingosine bases. IX. Degradation in vitro of dihydrospingosine and dihydrospingosine phosphate to palmitaldehyde and ethanolamine phosphate. Biological Chemistry. 349: 1745-1748. PMID 5707041 DOI: 10.1515/Bchm2.1968.349.2.1745  0.267
1968 Stoffel W, Lekim D, Sticht G. Biosynthesis of dihydrosphingosine in vitro. Biological Chemistry. 349: 664-670. PMID 4386961 DOI: 10.1515/Bchm2.1968.349.1.664  0.267
1991 Stoffel W, Binczek E. Transient expression of wild type and mutant human apolipoprotein AI in COS cells. Biological Chemistry Hoppe-Seyler. 372: 481-488. PMID 1930731 DOI: 10.1515/Bchm3.1991.372.2.481  0.265
1977 Stoffel W, Zierenberg O, Scheefers H. Reconstitution of Ca2 -ATPase of sarcoplasmic reticulum with 13C-labelled lipids 13C-NMR spectroscopic studies. Biological Chemistry. 358: 865-882. PMID 142743 DOI: 10.1515/Bchm2.1977.358.2.865  0.264
2012 Jungblut M, Tiveron MC, Barral S, Abrahamsen B, Knöbel S, Pennartz S, Schmitz J, Perraut M, Pfrieger FW, Stoffel W, Cremer H, Bosio A. Isolation and characterization of living primary astroglial cells using the new GLAST-specific monoclonal antibody ACSA-1. Glia. 60: 894-907. PMID 22374709 DOI: 10.1002/Glia.22322  0.262
1973 Stoffel W. Relationship between Sphingolipid and Phospholipid Metabolism Biochemical Society Transactions. 1: 336-341. DOI: 10.1042/Bst0010336  0.26
1968 Stoffel W, Schiefer H. Biosynthesis and composition of phosphatides in outer and inner mitochondrial membranes. Biological Chemistry. 349: 1017-1026. PMID 4300547 DOI: 10.1515/Bchm2.1968.349.2.1017  0.259
1967 Stoffel W, Sticht G. Metabolism of sphingosine bases. 3. Clinical syntheses of 14C and 3H labelled erythro- and threo-dihydrosphingosines and sphingosines. Biological Chemistry. 348: 1561-1569. PMID 5586902 DOI: 10.1515/Bchm2.1967.348.1.1561  0.258
1967 Stoffel W, Sticht G. Metabolism of sphingosine bases, II. Studies on the degradation and transformation of [3-14C]erythro-DL-dihydrosphingosine,[7-3H]erythro-DL-sphingosine,[5-3H]threo-L-dihydrosphingosine and [3-14C;1-3H]erythro-DL-dihydrosphingosine in rat liver. Biological Chemistry. 348: 1345-1351. PMID 5586467 DOI: 10.1515/Bchm2.1967.348.1.1345  0.258
1973 Henning R, Stoffel W. Glycosphingolipids in lysosomal membranes[1] Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 354: 760-770. PMID 4803509 DOI: 10.1515/Bchm2.1973.354.2.760  0.257
1970 Stoffel W, Lekim D, Heyn G. Metabolism of Sphingosine Bases, XIV. Sphinganine (Dihydrosphingosine), an Effective Donor of the Alk-1’-enyl Chain of Plasmalogens Biological Chemistry. 351: 875-883. PMID 5432753 DOI: 10.1515/Bchm2.1970.351.2.875  0.255
1972 Sticht G, Lekim D, Stoffel W. Chemical synthesis of D,L-3-dehydrosphinganine, its C14-, C16- and C20-homologues and the resolution into the enantiomeric forms Chemistry and Physics of Lipids. 8: 10-25. DOI: 10.1016/0009-3084(72)90039-4  0.254
1975 Stoffel W. [50] Chemical synthesis of choline-labeled lecithins and sphingomyelins Methods in Enzymology. 35: 533-541. PMID 164606 DOI: 10.1016/0076-6879(75)35181-1  0.253
1965 Stoffel W, Kahlke W. The transformation of phytol into 3,7,11,15-tetramethylhexadecanoic (phytanic) acid in heredopathia atactica polyneuritiformis (Refsum's syndrome) Biochemical and Biophysical Research Communications. 19: 33-36. DOI: 10.1016/0006-291X(65)90114-2  0.252
1969 Henning R, Stoffel W. The Relationship between Phospholipid Biosynthesis, Sphingosine Degradation and Serine Metabolism Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 350: 827-835. PMID 5806558 DOI: 10.1515/Bchm2.1969.350.2.827  0.252
1981 Stoffel W, Borberg H, Greve V. Application Of Specific Extracorporeal Removal Of Low Density Lipoprotein In Familial Hypercholesterolaemia The Lancet. 318: 1005-1007. PMID 6118475 DOI: 10.1016/S0140-6736(81)91213-7  0.251
1981 Stoffel W, Demant T. Selective removal of apolipoprotein B-containing serum lipoproteins from blood plasma. Proceedings of the National Academy of Sciences of the United States of America. 78: 611-615. PMID 7017720 DOI: 10.1073/Pnas.78.1.611  0.251
2004 Stoffel W, Körner R, Wachtmann D, Keller BU. Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice. Brain Research. Molecular Brain Research. 128: 170-81. PMID 15363892 DOI: 10.1016/J.Molbrainres.2004.06.026  0.251
1974 Stoffel W, Bister K. Studies on the desaturation of sphinganine. Ceramide and sphingomyelin metabolism in the rat and in BHK 21 cells in tissue culture. Biological Chemistry. 355: 911-923. PMID 4435766 DOI: 10.1515/Bchm2.1974.355.2.911  0.251
1969 Stoffel W, Trabert U. Studies on the occurrence and properties of lysosomal phospholipases A1 and A2 and the degradation of phosphatidic acid in rat liver lysosomes. Biological Chemistry. 350: 836-844. PMID 4308852 DOI: 10.1515/Bchm2.1969.350.2.836  0.247
1972 Stoffel W, Assmann G. Metabolism of Sphingosine Bases, XVIII. Degradation in Vitro of Phytosphingosine (4D-Hydroxysphinganine) Biological Chemistry. 353: 965-970. PMID 4340788 DOI: 10.1515/Bchm2.1972.353.1.965  0.247
1969 Stoffel W, Scheid A. [Metabolism of sphingosine bases. XII. Eicosasphinganine (eicosadihydrosphingosine) and 3-dehydroeicosasphinganine (3-dehydroeicosadihydrosphingosine)]. Biological Chemistry. 350: 1593-1604. PMID 5363657 DOI: 10.1515/Bchm2.1969.350.2.1593  0.247
2012 Schraven SP, Franz C, Rüttiger L, Löwenheim H, Lysakowski A, Stoffel W, Knipper M. Altered phenotype of the vestibular organ in GLAST-1 null mice. Journal of the Association For Research in Otolaryngology : Jaro. 13: 323-33. PMID 22350511 DOI: 10.1007/S10162-011-0311-2  0.245
1973 Stoffel W, Bister K. Stereospecificities in the metabolic reactions of the four isomeric sphinganines (dihydrosphingosines) in rat liver. Biological Chemistry. 354: 169-181. PMID 4372143 DOI: 10.1515/Bchm2.1973.354.1.169  0.244
2009 Dours-Zimmermann MT, Maurer K, Rauch U, Stoffel W, Fässler R, Zimmermann DR. Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7731-42. PMID 19535585 DOI: 10.1523/Jneurosci.4158-08.2009  0.243
2007 Stoffel W, Jenke B, Holz B, Binczek E, Günter RH, Knifka J, Koebke J, Niehoff A. Neutral sphingomyelinase (SMPD3) deficiency causes a novel form of chondrodysplasia and dwarfism that is rescued by Col2A1-driven smpd3 transgene expression. The American Journal of Pathology. 171: 153-61. PMID 17591962 DOI: 10.2353/Ajpath.2007.061285  0.242
1972 Stoffel W, Assmann G. On the metabolism of sphinganyl- and sphingenyl-1-phosphorylcholine. Biological Chemistry. 353: 65-74. PMID 4335782 DOI: 10.1515/Bchm2.1972.353.1.65  0.241
1971 Stoffel W, Binczek E. Metabolism of Sphingosine Bases, XVI. Studies on the Stereospecificity of the Introduction of the Hydroxy Group of 4D-Hydroxysphinganine (Phytosphingosine) Biological Chemistry. 352: 1065-1072. PMID 5098349 DOI: 10.1515/Bchm2.1971.352.2.1065  0.24
1965 Stoffel W, Schiefer H. Der Stoffwechsel der ungesättigten Fettsäuren, VI. Zur ß-Oxydation der Mono- und Polyenfettsäuren Untersuchungen in vivo und in vitro mit [3H, 14C]-und [1-14C]-markierten Mono- und Polyenfettsäuren* Biological Chemistry. 341: 84-90. DOI: 10.1515/Bchm2.1965.341.1.84  0.239
1978 Stoffel W, Metz P, Tunggal B. The binding of lysolecithin to human serum high density apoprotein A-I. A13C-NMR study. Biological Chemistry. 359: 465-472. PMID 206505 DOI: 10.1515/Bchm.1978.359.1.465  0.238
1974 Stoffel W, Bauer E, Stahl J. The metabolism of sphingosine bases in Tetrahymena pyriformis. Sphingosine kinase and sphingosine-1-phosphate lyase. Biological Chemistry. 355: 61-74. PMID 4373374 DOI: 10.1515/Bchm2.1974.355.1.61  0.237
1970 Stoffel W, Assmann G. Metabolism of Sphingosine Bases, XV. Enzymatic Degradation of 4t-Sphingenine 1-phosphate (Sphingosine 1-phosphate) to 2t-Hexadecen-1-al and Ethanolamine phosphate Biological Chemistry. 351: 1041-1049. PMID 4317971 DOI: 10.1515/Bchm2.1970.351.2.1041  0.237
1973 Stoffel W, Melzner I. Chemical synthesis of long chain 2-alkynals, alkynols, 2c- and 2t-alkenals and 2c- and 2t-alkenols. Biological Chemistry. 354: 1626-1632. PMID 4803851 DOI: 10.1515/Bchm2.1973.354.2.1626  0.236
1990 Stoffel W. Die Myelinmembran des Zentralnervensystems — essentielle makromolekulare Strukturen und Funktion Angewandte Chemie. 102: 987-1005. DOI: 10.1002/Ange.19901020905  0.235
1972 Assmann G, Stoffel W. Metabolism of Sphingosine Bases, XIX. On the Origin of Phytosphingosine (4D-Hydroxysphinganine) in Mammalian Tissues Biological Chemistry. 353: 971-979. PMID 5052951 DOI: 10.1515/Bchm2.1972.353.1.971  0.235
1995 Gutiérrez R, Boison D, Heinemann U, Stoffel W. Decompaction of CNS myelin leads to a reduction of the conduction velocity of action potentials in optic nerve Neuroscience Letters. 195: 93-96. PMID 7478276 DOI: 10.1016/0304-3940(94)11789-L  0.235
1976 Stoffel W, Därr W. Human high denisty apolipoprotein A-I-lysolecithin-lecithin and sphingomyelin complexes. A method for high yield recombinations to lipoprotein complexes of reproducible stoichiometry. Biological Chemistry. 357: 127-138. PMID 1254243 DOI: 10.1515/Bchm2.1976.357.1.127  0.234
1969 Stoffel W, Ecker W. [17] Δ3-cis,Δ2-trans-Enoyl-CoA isomerase from rat liver mitochondria Methods in Enzymology. 14: 99-105. DOI: 10.1016/S0076-6879(69)14019-7  0.233
1974 Stoffel W, Pruss HD, Sticht G. Monolayer studies on derivatives of sphinganine and 4t-sphingenine Chemistry and Physics of Lipids. 13: 466-480. DOI: 10.1016/0009-3084(74)90018-8  0.233
1973 LeKim D, Betzing H, Stoffel W. Studies in vivo and in vitro on the methylation of phosphatidyl-N,N-dimethylethanolamine to phosphatidylcholine in rat liver. Biological Chemistry. 354: 437-444. PMID 4803484 DOI: 10.1515/Bchm2.1973.354.1.437  0.23
1971 Stoffel W, Lekim D, Tschung TS. A simple chemical method for labelling phosphatidylcholine and sphingomyelin in the choline moiety. Biological Chemistry. 352: 1058-1064. PMID 5098348 DOI: 10.1515/Bchm2.1971.352.2.1058  0.229
1994 Klockner U, Storck T, Conradt M, Stoffel W. Functional Properties and Substrate Specificity of the Cloned L-Glutamate/L-Aspartate Transporter GLAST-1 from Rat Brain Expressed in Xenopus Oocytes The Journal of Neuroscience. 14: 5759-5765. DOI: 10.1523/Jneurosci.14-10-05759.1994  0.229
1974 Stoffel W, Därr W. 2-alkenal reductase isolation, properties and specificities. Biological Chemistry. 355: 54-60. PMID 4154890 DOI: 10.1515/Bchm2.1974.355.1.54  0.229
1973 Stoffel W, Hanfland P. Analysis of amino sugar-containing glycosphingolipids by combined gas-liquid chromatography and mass spectrometry. Biological Chemistry. 354: 21-31. PMID 4803239 DOI: 10.1515/Bchm2.1973.354.1.21  0.229
1966 Stoffel W, Schiefer H, Ditzer R. Der Stoffwechsel der ungesättigten Fettsäuren, VIII. Chemische Synthese und Stoffwechsel der [1-14C]7c.9c.12c-Octadecatriensäure und der [1-14C]7t.9c12c-Octadecatriensäure Biological Chemistry. 345: 52-60. DOI: 10.1515/Bchm2.1966.345.1.52  0.226
1964 Stoffel W, Ditzer R, Caesar H. The Metabolism of cis-β,γ-Enoyl-Coenzyme A Compounds Angewandte Chemie. 3: 386-387. DOI: 10.1002/Anie.196403861  0.225
1971 Stoffel W, Assmann G, Bister K. Metabolism of sphingosine bases. XVII. Stereospecificities in the introduction of the 4t-double bond into sphinganine yielding 4t-sphingenine (sphingosine). Biological Chemistry. 352: 1531-1544. PMID 5140816 DOI: 10.1515/Bchm2.1971.352.2.1531  0.225
2004 Haupt WF, Stoffel W. Nerve conduction velocity measurements reveal the functional deficit in ceramide galactosyl transferase-deficient (cgt-/-) mice. Journal of the Neurological Sciences. 217: 83-8. PMID 14675614 DOI: 10.1016/J.Jns.2003.09.004  0.225
1967 Stoffel W, Greten H. Studies on lipolytic activities of rat liver lysosomes. Biological Chemistry. 348: 1145-1150. PMID 5588274 DOI: 10.1515/Bchm2.1967.348.1.1145  0.224
1997 Zumbansen M, Stoffel W. Tumor Necrosis Factor α Activates NF-κB in Acid Sphingomyelinase-deficient Mouse Embryonic Fibroblasts Journal of Biological Chemistry. 272: 10904-10909. PMID 9099747 DOI: 10.1074/Jbc.272.16.10904  0.224
1998 Stoffel B, Bauer P, Nix M, Deres K, Stoffel W. Ceramide-independent CD28 and TCR signaling but reduced IL-2 secretion in T cells of acid sphingomyelinase-deficient mice European Journal of Immunology. 28: 874-880. PMID 9541582 DOI: 10.1002/(Sici)1521-4141(199803)28:03<874::Aid-Immu874>3.0.Co;2-T  0.224
1975 Stoffel W, Därr W. Purification and characterization of 2-alkenal reductase. Biological Chemistry. 356: 385-390. PMID 1150153 DOI: 10.1515/Bchm2.1975.356.1.385  0.223
1968 Stoffel W, Sticht G, Lekim D. Synthesis and degradation of spingosine bases in Hansenula ciferrii. Biological Chemistry. 349: 1149-1156. PMID 5706141 DOI: 10.1515/Bchm2.1968.349.2.1149  0.223
2000 Uschkureit T, Spörkel O, Stracke J, Büssow H, Stoffel W. Early onset of axonal degeneration in double (plp-/-mag-/-) and hypomyelinosis in triple (plp-/-mbp-/-mag-/-) mutant mice. The Journal of Neuroscience. 20: 5225-5233. DOI: 10.1523/Jneurosci.20-14-05225.2000  0.223
1964 Stoffel W. Synthese von [1‐14C]‐markierten all‐cis‐Polyenfettsäuren European Journal of Organic Chemistry. 673: 26-36. DOI: 10.1002/Jlac.19646730104  0.221
1988 Borberg H, Gaczkowski A, Hombach V, Oette K, Stoffel W. Treatment of familial hypocholesterolemia by means of specific immunoadsorption Journal of Clinical Apheresis. 4: 59-65. PMID 3294230 DOI: 10.1002/Jca.2920040204  0.22
1964 Stoffel W, Ach K. Der Stoffwechsel der ungesättigten Fettsäuren, II. Eigenschaften des kettenverlängernden Enzyms. Zur Frage der Biohydrogenierung der ungesättigten Fettsäuren Biological Chemistry. 337: 123-132. PMID 14238846 DOI: 10.1515/Bchm2.1964.337.1.123  0.218
1993 Müller-Newen G, Stoffel W. Site-directed mutagenesis of putative active-site amino acid residues of 3,2-trans-enoyl-CoA isomerase, conserved within the low-homology isomerase/hydratase enzyme family. Biochemistry. 32: 11405-12. PMID 8218206 DOI: 10.1021/BI00093A018  0.217
2021 Stoffel W, Binczek E, Schmidt-Soltau I, Brodesser S, Wegner I. High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis-inactivated Δ6-fatty acid desaturase-deficient mouse. Molecular Metabolism. 54: 101335. PMID 34530175 DOI: 10.1016/j.molmet.2021.101335  0.213
1969 Stoffel W, Pruss HD. Monolayer studies with synthetic saturated, mono- and polyunsaturated mixed 1,2-diglycerides, 1,2-diacylphosphatidylethanolamines and phosphatidylcholines at the air-water-interface. Hoppe-Seyler's Zeitschrift FüR Physiologische Chemie. 350: 1385-93. PMID 5362611 DOI: 10.1515/Bchm2.1969.350.2.1385  0.21
1967 Falke D, Schiefer H, Stoffel W. Notizen: Lipoid-Analysen bei Riesenzellbildung durch Herpesvirus Hominis Zeitschrift FüR Naturforschung B. 22: 1360-1362. DOI: 10.1515/Znb-1967-1231  0.209
1961 Stoffel W, Craig LC. Synthesis of Structures Related to Bacitracin A Journal of the American Chemical Society. 83: 145-149. DOI: 10.1021/Ja01462A029  0.208
1969 Stoffel W, Lekim D, Sticht G. Distribution and properties of dihydrosphingosine-1-phosphate aldolase (sphinganine-1-phosphate alkanal-lyase). Biological Chemistry. 350: 1233-1241. PMID 5389296 DOI: 10.1515/Bchm2.1969.350.2.1233  0.205
1966 Stoffel W, Wolf GD. Chemische Synthese von 1-O-[3H]Palmitoyl-L-glycerin-3-phosphat (L-3-Lysophosphatidsäure) Biological Chemistry. 347: 94-101. DOI: 10.1515/Bchm2.1966.347.1.94  0.205
1962 Stoffel W, Bierwirth E. Synthese 1‐14C‐markierter Polyenfettsäuren Angewandte Chemie. 74: 905-905. DOI: 10.1002/Ange.19620742218  0.203
1971 Stoffel W, Lekim D. Studies on the biosynthesis of plasmalogens. Precursors in the biosynthesis of plasmalogens: on the stereospecificity of the biochemical dehydrogenation of the 1-O-alkyl glyceryl to the 1-O-alk-1'-enyl glyceryl ether bond. Biological Chemistry. 352: 501-511. PMID 5550967 DOI: 10.1515/Bchm2.1971.352.1.501  0.203
1966 Stoffel W. Über Biosynthese und biologischen Abbau hochungesättigter Fettsäuren Naturwissenschaften. 53: 621-630. PMID 4867050 DOI: 10.1007/Bf00602718  0.202
1963 Stoffel W, Bierwirth E. Synthesis of 1-14C-Labelled Polyunsaturated Fatty Acids Angewandte Chemie International Edition in English. 2: 94-95. DOI: 10.1002/ANIE.196300943  0.196
1967 Stoffel W, Scheid A. Zur Polyenfettsäure- und Phospholipoidsynthese in der Gewebekultur von HeLa-Zellen Biological Chemistry. 348: 205-226. DOI: 10.1515/Bchm2.1967.348.1.205  0.194
1967 Stoffel W, Tomás MED, Schiefer H. Die enzymatische Acylierung von Lysophosphatidsäure, gesättigtem und ungesättigtem Lysolecithin Biological Chemistry. 348: 882-890. DOI: 10.1515/Bchm2.1967.348.1.882  0.191
1964 Stoffel W, Ditzer R, Caesar H. Der Stoffwechsel von cis-β,γ-Enoyl-Coenzym A-Verbindungen Angewandte Chemie. 76: 440-441. DOI: 10.1002/Ange.19640761025  0.191
1973 Stoffel W, Hellenbroich B, Heimann G. Properties and Specificities of Sphingosine Kinase from Blood Platelets Biological Chemistry. 354: 1311-1316. PMID 4373363 DOI: 10.1515/Bchm2.1973.354.2.1311  0.189
1960 Hirsch J, Farquhar JW, Ahrens EH, Peterson ML, Stoffel W. Studies of Adipose Tissue in Man A Microtechnic for Sampling and Analysis The American Journal of Clinical Nutrition. 8: 499-511. PMID 13714574 DOI: 10.1093/Ajcn/8.4.499  0.187
1992 Tunggal BD, Hofmann K, Stoffel W, Oette K, Diekmann H, Walger M, Wedel Hv. In vivo nuclear magnetic resonance at 4.7 tesla. Naturwissenschaften. 79: 512-516. PMID 1465150 DOI: 10.1007/Bf01135770  0.185
1996 STOFFEL W. CHEMICAL SYNTHESIS OF H3- AND 1-C-14-LABELED POLYUNSATURATED FATTY ACIDS. Journal of the American Oil Chemists' Society. 42: 583-7. PMID 14328356 DOI: 10.1007/BF02541294  0.183
1972 Heckers H, Stoffel W. Sphingolipids in blood platelets of the pig. Biological Chemistry. 353: 407-418. PMID 5063717 DOI: 10.1515/Bchm2.1972.353.1.407  0.18
1973 Stoffel W, Heimann G, Hellenbroich B. Sphingosine kinase in blood platelets. Biological Chemistry. 354: 562-566. PMID 4372149 DOI: 10.1515/Bchm2.1973.354.1.562  0.178
1977 Stoffel W, Sorgo W. Asymmetry of the lipid-bilayer of Sindbis virus. Chemistry and Physics of Lipids. 17: 324-35. PMID 991384 DOI: 10.1016/0009-3084(76)90077-3  0.177
1971 Stoffel W, Assad H, Sprecher H. Enzymatic studies on the mechanism of the retroconversion of C22-polyenoic fatty acids to their C20-homologues. Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 351: 1545-54. PMID 5491611 DOI: 10.1515/BCHM2.1970.351.2.1545  0.167
1981 Podack ER, Stoffel W, Esser AF, Müller-Eberhard HJ. Membrane attack complex of complement: distribution of subunits between the hydrocarbon phase of target membranes and water. Proceedings of the National Academy of Sciences of the United States of America. 78: 4544-8. PMID 6270682 DOI: 10.1073/Pnas.78.7.4544  0.165
1979 Stoffel W, Preissner K. Conformational analysis of serum apolipoprotein AII in lipoprotein complexes with bifunctional crosslinking reagents. Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 360: 691-707. PMID 223956 DOI: 10.1515/BCHM2.1979.360.1.691  0.162
1995 Hoffmann M, Stoffel W. Functional characterization of a fusion protein of human lipoprotein lipase and apolipoprotein C-II Atherosclerosis. 115: S116. DOI: 10.1016/0021-9150(95)96693-M  0.148
1969 Stoffel W, Sticht G, Le Kim D. Metabolism of sphingosine bases. X. Degradation of (1-14C)dihydrosphingosine (Sphinganine), (1-14C)2-Amino-1,3-dihydroxyheptane and (1-14C)dihydrosphingosine phosphate in rat liver. Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 350: 63-8. PMID 5764920 DOI: 10.1515/BCHM2.1969.350.1.63  0.145
2001 Stoffel W. Phenotype of acid sphingomyelinase deficiency knockout mice Cell Death & Differentiation. 8: 103-103. DOI: 10.1038/sj.cdd.4400789  0.134
1990 Haase A, Stoffel W. The 3'-flanking region shared by the human apolipoprotein AI and CIII gene regulates gene expression in cooperation with 5'-flanking elements. Biological Chemistry Hoppe-Seyler. 371: 375-82. PMID 2111147 DOI: 10.1515/BCHM3.1990.371.1.375  0.129
1976 Binaglia L, Karageosian K, Stoffel W. Phospho- and glycosphingolipid metabolism in a rat neuri-noma clone (RN6) studied in tissue culture. Advances in Experimental Medicine and Biology. 72: 131-7. PMID 945936 DOI: 10.1007/978-1-4684-0955-0_12  0.104
1979 Fleischer S, McIntyre JO, Stoffel W, Tunggal BD. Carbon-13 nuclear magnetic resonance studies of the interaction of lecithin with purified D-beta-hydroxybutyrate apodehydrogenase, a lipid-requiring enzyme. Biochemistry. 18: 2420-9. PMID 444466 DOI: 10.1021/bi00578a043  0.1
1993 Klöckner U, Storck T, Conradt M, Stoffel W. Electrogenic L-glutamate uptake in Xenopus laevis oocytes expressing a cloned rat brain L-glutamate/L-aspartate transporter (GLAST-1) Journal of Biological Chemistry. 268: 14594-14596. DOI: 10.1016/s0021-9258(18)82373-0  0.074
1987 Hombach V, Borberg H, Gadzkowski A, Oette K, Stoffel W. [Regression of coronary sclerosis in familial hypercholesterolemia IIa by specific LDL apheresis]. Deutsche Medizinische Wochenschrift (1946). 111: 1709-15. PMID 3536386 DOI: 10.1055/S-2008-1068697  0.059
1991 Danis J, Tunggal B, Weyer J, Meyer G, Saad S, Isselhard W, Stoffel W, Hesse UJ. 31P NMR spectroscopy for in vitro viability testing of porcine pancreatic islets. The Journal of Surgical Research. 49: 534-8. PMID 1702170 DOI: 10.1016/0022-4804(90)90179-6  0.052
2002 Dinslage S, Stoffel W, Diestelhorst M, Krieglstein GK. Tolerability and safety of two new preservative-free tear film substitutes. Cornea. 21: 352-5. PMID 11973381  0.017
1955 Klenk E, Stoffel W. Über neuraminsäurehaltige Glykoproteide des Blutserums Hoppe-Seyler´S Zeitschrift FüR Physiologische Chemie. 302: 286-288. DOI: 10.1515/BCHM2.1955.302.1-2.286  0.016
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