Year |
Citation |
Score |
2023 |
Khan H, Ochi T. Plant PAXX has an XLF-like function and stimulates DNA end joining by the Ku-DNA ligase IV/XRCC4 complex. The Plant Journal : For Cell and Molecular Biology. PMID 37340932 DOI: 10.1111/tpj.16359 |
0.732 |
|
2022 |
Goff NJ, Brenière M, Buehl CJ, de Melo AJ, Huskova H, Ochi T, Blundell TL, Mao W, Yu K, Modesti M, Meek K. Catalytically inactive DNA ligase IV promotes DNA repair in living cells. Nucleic Acids Research. PMID 36263813 DOI: 10.1093/nar/gkac913 |
0.705 |
|
2020 |
Ochi T, Quarantotti V, Lin H, Jullien J, Rosa E Silva I, Boselli F, Barnabas DD, Johnson CM, McLaughlin SH, Freund SMV, Blackford AN, Kimata Y, Goldstein RE, Jackson SP, Blundell TL, et al. CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions. Structure (London, England : 1993). PMID 32375023 DOI: 10.1016/J.Str.2020.04.010 |
0.497 |
|
2019 |
Wu Q, Liang S, Ochi T, Chirgadze DY, Huiskonen JT, Blundell TL. Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways. Progress in Biophysics and Molecular Biology. PMID 31014919 DOI: 10.1016/J.Pbiomolbio.2019.03.007 |
0.77 |
|
2018 |
Wang JL, Duboc C, Wu Q, Ochi T, Liang S, Tsutakawa SE, Lees-Miller SP, Nadal M, Tainer JA, Blundell TL, Strick TR. Dissection of DNA double-strand-break repair using novel single-molecule forceps. Nature Structural & Molecular Biology. PMID 29786079 DOI: 10.1038/S41594-018-0065-1 |
0.764 |
|
2016 |
Chang HH, Watanabe G, Gerodimos CA, Ochi T, Blundell TL, Jackson SP, Lieber MR. Different DNA End Configurations Dictate Which NHEJ Components are Most Important for Joining Efficiency. The Journal of Biological Chemistry. PMID 27703001 DOI: 10.1074/Jbc.M116.752329 |
0.761 |
|
2016 |
Wu Q, Paul A, Su D, Mehmood S, Foo TK, Ochi T, Bunting EL, Xia B, Robinson CV, Wang B, Blundell TL. Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites. Molecular Cell. PMID 26778126 DOI: 10.1016/J.Molcel.2015.12.017 |
0.722 |
|
2016 |
Liang S, Esswein SR, Ochi T, Wu Q, Ascher DB, Chirgadze D, Sibanda BL, Blundell TL. Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached Structural Chemistry. 28: 161-171. DOI: 10.1007/S11224-016-0841-7 |
0.684 |
|
2015 |
Murray JE, van der Burg M, IJspeert H, Carroll P, Wu Q, Ochi T, Leitch A, Miller ES, Kysela B, Jawad A, Bottani A, Brancati F, Cappa M, Cormier-Daire V, Deshpande C, et al. Mutations in the NHEJ component XRCC4 cause primordial dwarfism. American Journal of Human Genetics. 96: 412-24. PMID 25728776 DOI: 10.1016/J.Ajhg.2015.01.013 |
0.609 |
|
2015 |
Ochi T, Blackford AN, Coates J, Jhujh S, Mehmood S, Tamura N, Travers J, Wu Q, Draviam VM, Robinson CV, Blundell TL, Jackson SP. DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science (New York, N.Y.). 347: 185-8. PMID 25574025 DOI: 10.1126/Science.1261971 |
0.764 |
|
2015 |
Ascher DB, Jubb HC, Pires DEV, Ochi T, Higueruelo A, Blundell TL. Protein-protein interactions: Structures and druggability Nato Science For Peace and Security Series a: Chemistry and Biology. 38: 141-163. DOI: 10.1007/978-94-017-9719-1_12 |
0.619 |
|
2014 |
Ochi T, Wu Q, Blundell TL. The spatial organization of non-homologous end joining: from bridging to end joining. Dna Repair. 17: 98-109. PMID 24636752 DOI: 10.1016/J.Dnarep.2014.02.010 |
0.775 |
|
2013 |
Ochi T, Gu X, Blundell TL. Structure of the catalytic region of DNA ligase IV in complex with an Artemis fragment sheds light on double-strand break repair. Structure (London, England : 1993). 21: 672-9. PMID 23523427 DOI: 10.1016/J.Str.2013.02.014 |
0.747 |
|
2012 |
Ochi T, Wu Q, Chirgadze DY, Grossmann JG, Bolanos-Garcia VM, Blundell TL. Structural insights into the role of domain flexibility in human DNA ligase IV. Structure (London, England : 1993). 20: 1212-22. PMID 22658747 DOI: 10.1016/J.Str.2012.04.012 |
0.765 |
|
2012 |
Bolanos-Garcia VM, Wu Q, Ochi T, Chirgadze DY, Sibanda BL, Blundell TL. Spatial and temporal organization of multi-protein assemblies: achieving sensitive control in information-rich cell-regulatory systems. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 370: 3023-39. PMID 22615474 DOI: 10.1098/Rsta.2011.0268 |
0.73 |
|
2012 |
Wu Q, Sibanda L, Ochi T, Bolanos-Garcia VM, Blundell TL, Chirgadze DY. Spatial and temporal organisation of multiprotein systems of cell regulation and signalling: What can we learn from NHEJ system of double-strand break repair? Nato Science For Peace and Security Series a: Chemistry and Biology. 1-31. DOI: 10.1007/978-94-007-2530-0_1 |
0.511 |
|
2011 |
Wu Q, Ochi T, Matak-Vinkovic D, Robinson CV, Chirgadze DY, Blundell TL. Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions. Biochemical Society Transactions. 39: 1387-92, suppl 2 p f. PMID 21936820 DOI: 10.1042/Bst0391387 |
0.681 |
|
2010 |
Ochi T, Sibanda BL, Wu Q, Chirgadze DY, Bolanos-Garcia VM, Blundell TL. Structural biology of DNA repair: spatial organisation of the multicomponent complexes of nonhomologous end joining. Journal of Nucleic Acids. 2010. PMID 20862368 DOI: 10.4061/2010/621695 |
0.81 |
|
2009 |
Ochi T, Bolanos-Garcia VM, Stojanoff V, Moreno A. Perspectives on protein crystallisation. Progress in Biophysics and Molecular Biology. 101: 56-63. PMID 20005246 DOI: 10.1016/J.Pbiomolbio.2009.12.001 |
0.659 |
|
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