Peter Friedl, M.D., Ph.D. - Publications

Affiliations: 
University of Texas MD Anderson Cancer Center, Houston, TX, United States 

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Friedl P, Zegers M. A collective strategy to promote the dissemination of single cancer cells. The Journal of Cell Biology. 223. PMID 38717454 DOI: 10.1083/jcb.202405014  0.308
2024 Konstantopoulos K, Tran A, Wisniewski E, Mistriotis P, Stoletov K, Parlani M, Amitrano A, Ifemembi B, Lee SJ, Bera K, Zhang Y, Tuntithavornwat S, Afthinos A, Kiepas A, Jamieson J, ... ... Friedl P, et al. Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion. Research Square. PMID 38260442 DOI: 10.21203/rs.3.rs-3640969/v1  0.362
2023 Beunk L, Wen N, van Helvert S, Bekker B, Ran L, Kang R, Paulat T, Syga S, Deutsch A, Friedl P, Wolf K. Cell jamming in a collagen-based interface assay: tuning by collagen density and proteolysis. Journal of Cell Science. PMID 37987169 DOI: 10.1242/jcs.260207  0.335
2023 Weiss F, Atlasy N, van Reijmersdal V, Stunnenberg H, Hulsbergen-Veelken C, Friedl P. 3D spheroid culture to examine adaptive therapy response in invading tumor cells. In Vitro Models. 1: 463-471. PMID 37096022 DOI: 10.1007/s44164-022-00040-x  0.325
2023 Law RA, Kiepas A, Desta HE, Perez Ipiña E, Parlani M, Lee SJ, Yankaskas CL, Zhao R, Mistriotis P, Wang N, Gu Z, Kalab P, Friedl P, Camley BA, Konstantopoulos K. Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement. Science Advances. 9: eabq6480. PMID 36630496 DOI: 10.1126/sciadv.abq6480  0.385
2022 Friedl P, Konstantopoulos K, Sahai E, Weiner O. Adhesion-independent topography-based leukocyte migration. Faculty Reviews. 11: 18. PMID 35979144 DOI: 10.12703/r-01-0000013  0.336
2022 Beunk L, Bakker GJ, van Ens D, Bugter J, Gal F, Svoren M, Friedl P, Wolf K. Actomyosin contractility requirements and reciprocal cell-tissue mechanics for cancer cell invasion through collagen-based channels. The European Physical Journal. E, Soft Matter. 45: 48. PMID 35575822 DOI: 10.1140/epje/s10189-022-00182-6  0.357
2021 Weigelin B, den Boer AT, Wagena E, Broen K, Dolstra H, de Boer RJ, Figdor CG, Textor J, Friedl P. Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity. Nature Communications. 12: 5217. PMID 34471116 DOI: 10.1038/s41467-021-25282-3  0.316
2020 Ilina O, Gritsenko PG, Syga S, Lippoldt J, La Porta CAM, Chepizhko O, Grosser S, Vullings M, Bakker GJ, Starruß J, Bult P, Zapperi S, Käs JA, Deutsch A, Friedl P. Cell-cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion. Nature Cell Biology. PMID 32839548 DOI: 10.1038/S41556-020-0552-6  0.498
2020 Wisniewski EO, Mistriotis P, Bera K, Law RA, Zhang J, Nikolic M, Weiger M, Parlani M, Tuntithavornwat S, Afthinos A, Zhao R, Wirtz D, Kalab P, Scarcelli G, Friedl P, et al. Dorsoventral polarity directs cell responses to migration track geometries. Science Advances. 6: eaba6505. PMID 32789173 DOI: 10.1126/Sciadv.Aba6505  0.402
2020 Khalil AA, Ilina O, Vasaturo A, Venhuizen JH, Vullings M, Venhuizen V, Bilos A, Figdor CG, Span PN, Friedl P. Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels. The Journal of Cell Biology. 219. PMID 32777015 DOI: 10.1083/Jcb.201911120  0.45
2020 Deutsch A, Friedl P, Preziosi L, Theraulaz G. Multi-scale analysis and modelling of collective migration in biological systems. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 375: 20190377. PMID 32713301 DOI: 10.1098/Rstb.2019.0377  0.342
2020 Gonzalez-Beltran AN, Masuzzo P, Ampe C, Bakker GJ, Besson S, Eibl RH, Friedl P, Gunzer M, Kittisopikul M, Dévédec SEL, Leo S, Moore J, Paran Y, Prilusky J, Rocca-Serra P, et al. Community standards for open cell migration data. Gigascience. 9. PMID 32396199 DOI: 10.1093/Gigascience/Giaa041  0.374
2020 Gritsenko PG, Atlasy N, Dieteren CEJ, Navis AC, Venhuizen JH, Veelken C, Schubert D, Acker-Palmer A, Westerman BA, Wurdinger T, Leenders W, Wesseling P, Stunnenberg HG, Friedl P. p120-catenin-dependent collective brain infiltration by glioma cell networks. Nature Cell Biology. 22: 97-107. PMID 31907411 DOI: 10.1038/S41556-019-0443-X  0.353
2019 Friedl P. Rethinking research into metastasis. Elife. 8. PMID 31845646 DOI: 10.7554/Elife.53511  0.335
2019 Haeger A, Alexander S, Vullings M, Kaiser FMP, Veelken C, Flucke U, Koehl GE, Hirschberg M, Flentje M, Hoffman RM, Geissler EK, Kissler S, Friedl P. Collective cancer invasion forms an integrin-dependent radioresistant niche. The Journal of Experimental Medicine. PMID 31658985 DOI: 10.1084/Jem.20181184  0.365
2019 Venhuizen JH, Span PN, van den Dries K, Sommer S, Friedl P, Zegers MM. P120 Catenin Isoforms Differentially Associate with Breast Cancer Invasion and Metastasis. Cancers. 11. PMID 31569498 DOI: 10.3390/Cancers11101459  0.37
2019 Paindelli C, Navone N, Logothetis CJ, Friedl P, Dondossola E. Engineered bone for probing organotypic growth and therapy response of prostate cancer tumoroids in vitro. Biomaterials. 197: 296-304. PMID 30682644 DOI: 10.1016/J.Biomaterials.2019.01.027  0.345
2019 Dondossola E, Casarin S, Paindelli C, De-Juan-Pardo EM, Hutmacher DW, Logothetis CJ, Friedl P. Radium 223-mediated zonal cytotoxicity of prostate cancer in bone. Journal of the National Cancer Institute. PMID 30657953 DOI: 10.1093/Jnci/Djz007  0.312
2019 Venhuizen JH, Sommer S, Span PN, Friedl P, Zegers MM. Differential expression of p120-catenin 1 and 3 isoforms in epithelial tissues. Scientific Reports. 9: 90. PMID 30643202 DOI: 10.1038/S41598-018-36889-W  0.309
2018 Huda S, Weigelin B, Wolf K, Tretiakov KV, Polev K, Wilk G, Iwasa M, Emami FS, Narojczyk JW, Banaszak M, Soh S, Pilans D, Vahid A, Makurath M, Friedl P, et al. Lévy-like movement patterns of metastatic cancer cells revealed in microfabricated systems and implicated in vivo. Nature Communications. 9: 4539. PMID 30382086 DOI: 10.1038/S41467-018-06563-W  0.419
2018 Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P. Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone. Science Translational Medicine. 10. PMID 30068572 DOI: 10.1126/Scitranslmed.Aao5726  0.302
2018 Beunk L, Brown K, Nagtegaal I, Friedl P, Wolf K. Cancer invasion into musculature: mechanics, molecules and implications. Seminars in Cell & Developmental Biology. PMID 30009945 DOI: 10.1016/J.Semcdb.2018.07.014  0.406
2018 Ilina O, Campanello L, Gritsenko PG, Vullings M, Wang C, Bult P, Losert W, Friedl P. Intravital microscopy of collective invasion plasticity in breast cancer. Disease Models & Mechanisms. PMID 29997220 DOI: 10.1242/Dmm.034330  0.453
2018 Odenthal J, Rijpkema M, Bos D, Wagena E, Croes H, Grenman R, Boerman O, Takes R, Friedl P. Targeting CD44v6 for fluorescence-guided surgery in head and neck squamous cell carcinoma. Scientific Reports. 8: 10467. PMID 29992954 DOI: 10.1038/S41598-018-28059-9  0.347
2018 Gritsenko PG, Friedl P. Adaptive adhesion systems mediate glioma cell invasion in complex environments. Journal of Cell Science. PMID 29991514 DOI: 10.1242/Jcs.216382  0.409
2018 van Helvert S, Storm C, Friedl P. Mechanoreciprocity in cell migration. Nature Cell Biology. 20: 8-20. PMID 29269951 DOI: 10.1038/S41556-017-0012-0  0.465
2017 Khalil AA, Ilina O, Gritsenko PG, Bult P, Span PN, Friedl P. Collective invasion in ductal and lobular breast cancer associates with distant metastasis. Clinical & Experimental Metastasis. 34: 421-429. PMID 28894989 DOI: 10.1007/S10585-017-9858-6  0.347
2017 Gritsenko P, Leenders W, Friedl P. Recapitulating in vivo-like plasticity of glioma cell invasion along blood vessels and in astrocyte-rich stroma. Histochemistry and Cell Biology. 148: 395-406. PMID 28825130 DOI: 10.1007/S00418-017-1604-2  0.396
2017 Veelken C, Bakker GJ, Drell D, Friedl P. Single cell-based automated quantification of therapy responses of invasive cancer spheroids in organotypic 3D culture. Methods (San Diego, Calif.). 128: 139-149. PMID 28739118 DOI: 10.1016/J.Ymeth.2017.07.015  0.355
2017 Hofschröer V, Koch KA, Ludwig FT, Friedl P, Oberleithner H, Stock C, Schwab A. Extracellular protonation modulates cell-cell interaction mechanics and tissue invasion in human melanoma cells. Scientific Reports. 7: 42369. PMID 28205573 DOI: 10.1038/Srep42369  0.487
2017 Friedl P, Mayor R. Tuning Collective Cell Migration by Cell-Cell Junction Regulation. Cold Spring Harbor Perspectives in Biology. PMID 28096261 DOI: 10.1101/Cshperspect.A029199  0.476
2017 Lehmann S, Te Boekhorst V, Odenthal J, Bianchi R, van Helvert S, Ikenberg K, Ilina O, Stoma S, Xandry J, Jiang L, Grenman R, Rudin M, Friedl P. Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells. Current Biology : Cb. PMID 28089517 DOI: 10.1016/J.Cub.2016.11.057  0.49
2016 Dondossola E, Holzapfel BM, Alexander S, Filippini S, Hutmacher DW, Friedl P. Examination of the foreign body response to biomaterials by nonlinear intravital microscopy. Nature Biomedical Engineering. 1. PMID 28979821 DOI: 10.1038/S41551-016-0007  0.377
2016 Odenthal J, Takes R, Friedl P. Plasticity of tumor cell invasion: governance by growth factors and cytokines. Carcinogenesis. 37: 1117-1128. PMID 27664164 DOI: 10.1093/Carcin/Bgw098  0.436
2016 Boekhorst VAMt, Friedl P. Plasticity of Cancer Cell Invasion—Mechanisms and Implications for Therapy Advances in Cancer Research. 132: 209-264. PMID 27613134 DOI: 10.1016/Bs.Acr.2016.07.005  0.5
2016 Te Boekhorst V, Preziosi L, Friedl P. Plasticity of Cell Migration In Vivo and In Silico. Annual Review of Cell and Developmental Biology. 32: 491-526. PMID 27576118 DOI: 10.1146/Annurev-Cellbio-111315-125201  0.485
2016 Weigelin B, Friedl P. Cancer cells: Stemness shaped by curvature. Nature Materials. 15: 827-8. PMID 27443907 DOI: 10.1038/Nmat4711  0.375
2016 van Helvert S, Friedl P. Strain Stiffening of Fibrillar Collagen during Individual and Collective Cell Migration Identified by AFM Nanoindentation. Acs Applied Materials & Interfaces. PMID 27128771 DOI: 10.1021/Acsami.6B01755  0.383
2016 Denais CM, Gilbert RM, Isermann P, McGregor AL, Te Lindert M, Weigelin B, Davidson PM, Friedl P, Wolf K, Lammerding J. Nuclear envelope rupture and repair during cancer cell migration. Science (New York, N.Y.). PMID 27013428 DOI: 10.1126/Science.Aad7297  0.434
2016 Weigelin B, Bolaños E, Rodriguez-Ruiz ME, Martinez-Forero I, Friedl P, Melero I. Anti-CD137 monoclonal antibodies and adoptive T cell therapy: a perfect marriage? Cancer Immunology, Immunotherapy : Cii. 65: 493-7. PMID 26970765 DOI: 10.1007/S00262-016-1818-5  0.345
2016 Weigelin B, Bakker GJ, Friedl P. Third harmonic generation microscopy of cells and tissue organization. Journal of Cell Science. PMID 26743082 DOI: 10.1242/Jcs.152272  0.408
2016 Dondossola E, Alexander S, Alexander S, Holzapfel B, Logothetis C, Hutmacher D, Friedl P. Abstract PR04: Intravital microscopy of prostate cancer lesions in bone: Kinetics of osteolysis and therapy response Cancer Research. 76: 2681-2681. DOI: 10.1158/1538-7445.Tummet15-Pr04  0.321
2016 Boekhorst Vt, Jiang L, Lehmann S, Zuidema A, Friedl P. Abstract 5062: Hypoxia-induced amoeboid cancer cell migration Cancer Research. 76: 5062-5062. DOI: 10.1158/1538-7445.Am2016-5062  0.484
2015 Haeger A, Wolf K, Zegers MM, Friedl P. Collective cell migration: guidance principles and hierarchies. Trends in Cell Biology. PMID 26137890 DOI: 10.1016/J.Tcb.2015.06.003  0.467
2015 Zegers MM, Friedl P. Translating Membrane Tension into Cytoskeletal Action by FBP17. Developmental Cell. 33: 628-30. PMID 26102599 DOI: 10.1016/J.Devcel.2015.06.006  0.348
2015 Weigelin B, Bolaños E, Teijeira A, Martinez-Forero I, Labiano S, Azpilikueta A, Morales-Kastresana A, Quetglas JI, Wagena E, Sánchez-Paulete AR, Chen L, Friedl P, Melero I. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proceedings of the National Academy of Sciences of the United States of America. 112: 7551-6. PMID 26034288 DOI: 10.1073/pnas.1506357112  0.364
2015 Chatterji T, Varkaris AS, Parikh NU, Song JH, Cheng CJ, Schweppe RE, Alexander S, Davis JW, Troncoso P, Friedl P, Kuang J, Lin SH, Gallick GE. Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells. Oncotarget. 6: 10175-94. PMID 25868388 DOI: 10.18632/Oncotarget.3391  0.343
2015 Lehmann S, Boekhorst VAMt, Odenthal J, Jiang L, Helvert Sv, Friedl P. Abstract 4141: Hypoxia-induced transition from collective to amoeboid single cell dissemination in epithelial cancer cells Cancer Research. 75: 4141-4141. DOI: 10.1158/1538-7445.Am2015-4141  0.498
2015 Friedl P. Abstract CN05-04: Serial killing of tumor cells by cytotoxic T cells: Mechanisms and implications for therapy Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Cn05-04  0.44
2014 Friedl P, Weigelin B. A Swiss Army knife for CTLs. Immunity. 41: 873-5. PMID 25526299 DOI: 10.1016/J.Immuni.2014.12.008  0.336
2014 Starke J, Wehrle-Haller B, Friedl P. Plasticity of the actin cytoskeleton in response to extracellular matrix nanostructure and dimensionality. Biochemical Society Transactions. 42: 1356-66. PMID 25233415 DOI: 10.1042/Bst20140139  0.405
2014 Zegers MM, Friedl P. Rho GTPases in collective cell migration. Small Gtpases. 5: e28997. PMID 25054920 DOI: 10.4161/Sgtp.28997  0.479
2014 Haeger A, Krause M, Wolf K, Friedl P. Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement. Biochimica Et Biophysica Acta. 1840: 2386-95. PMID 24721714 DOI: 10.1016/J.Bbagen.2014.03.020  0.508
2014 Friedl P, Wolf K, Zegers MM. Rho-directed forces in collective migration. Nature Cell Biology. 16: 208-10. PMID 24576897 DOI: 10.1038/Ncb2923  0.427
2014 Dondossola E, Alexander S, Alexander S, Holzapfel BM, Logothetis CJ, Hutmacher DW, Friedl P. Abstract 4941: A humanized bone model for preclinical monitoring of prostate cancer lesions by intravital multiphoton microscopy Cancer Research. 74: 4941-4941. DOI: 10.1158/1538-7445.Am2014-4941  0.349
2013 Häger A, Alexander S, Friedl P. Cancer invasion and resistance. Ejc Supplements : Ejc : Official Journal of Eortc, European Organization For Research and Treatment of Cancer ... [Et Al.]. 11: 291-3. PMID 26217149 DOI: 10.1016/J.Ejcsup.2013.07.055  0.45
2013 Alexander S, Weigelin B, Winkler F, Friedl P. Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response. Current Opinion in Cell Biology. 25: 659-71. PMID 23896198 DOI: 10.1016/J.Ceb.2013.07.001  0.463
2013 Starke J, Maaser K, Wehrle-Haller B, Friedl P. Mechanotransduction of mesenchymal melanoma cell invasion into 3D collagen lattices: filopod-mediated extension-relaxation cycles and force anisotropy. Experimental Cell Research. 319: 2424-33. PMID 23830878 DOI: 10.1016/J.Yexcr.2013.04.003  0.467
2013 Wolf K, Te Lindert M, Krause M, Alexander S, Te Riet J, Willis AL, Hoffman RM, Figdor CG, Weiss SJ, Friedl P. Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. The Journal of Cell Biology. 201: 1069-84. PMID 23798731 DOI: 10.1083/Jcb.201210152  0.439
2012 Weigelin B, Bakker GJ, Friedl P. Intravital third harmonic generation microscopy of collective melanoma cell invasion: Principles of interface guidance and microvesicle dynamics. Intravital. 1: 32-43. PMID 29607252 DOI: 10.4161/intv.21223  0.356
2012 Friedl P, Sahai E, Weiss S, Yamada KM. New dimensions in cell migration. Nature Reviews. Molecular Cell Biology. 13: 743-7. PMID 23072889 DOI: 10.1038/Nrm3459  0.478
2012 Friedl P, Locker J, Sahai E, Segall JE. Classifying collective cancer cell invasion. Nature Cell Biology. 14: 777-83. PMID 22854810 DOI: 10.1038/Ncb2548  0.472
2012 Bonetto F, Srinivas M, Weigelin B, Cruz LJ, Heerschap A, Friedl P, Figdor CG, de Vries IJ. A large-scale (19)F MRI-based cell migration assay to optimize cell therapy. Nmr in Biomedicine. 25: 1095-103. PMID 22315137 DOI: 10.1002/Nbm.2774  0.466
2012 Bakker GJ, Andresen V, Hoffman RM, Friedl P. Fluorescence lifetime microscopy of tumor cell invasion, drug delivery, and cytotoxicity. Methods in Enzymology. 504: 109-25. PMID 22264531 DOI: 10.1016/B978-0-12-391857-4.00005-7  0.402
2012 Friedl P, Hubbell J, Livingston D, Mihich E. Twenty-third annual Pezcoller Symposium: engineering influences in cancer research. Cancer Research. 72: 841-4. PMID 22237623 DOI: 10.1158/0008-5472.Can-11-3080  0.393
2012 Alexander S, Friedl P. Cancer invasion and resistance: interconnected processes of disease progression and therapy failure. Trends in Molecular Medicine. 18: 13-26. PMID 22177734 DOI: 10.1016/J.Molmed.2011.11.003  0.376
2012 Gritsenko PG, Ilina O, Friedl P. Interstitial guidance of cancer invasion. The Journal of Pathology. 226: 185-99. PMID 22006671 DOI: 10.1002/Path.3031  0.439
2011 Friedl P, Alexander S. Cancer invasion and the microenvironment: plasticity and reciprocity. Cell. 147: 992-1009. PMID 22118458 DOI: 10.1016/J.Cell.2011.11.016  0.522
2011 Wolf K, Friedl P. Extracellular matrix determinants of proteolytic and non-proteolytic cell migration. Trends in Cell Biology. 21: 736-44. PMID 22036198 DOI: 10.1016/J.Tcb.2011.09.006  0.474
2011 Weigelin B, Krause M, Friedl P. Cytotoxic T lymphocyte migration and effector function in the tumor microenvironment. Immunology Letters. 138: 19-21. PMID 21333682 DOI: 10.1016/J.Imlet.2011.02.016  0.362
2011 Ilina O, Bakker GJ, Vasaturo A, Hofmann RM, Friedl P. Two-photon laser-generated microtracks in 3D collagen lattices: principles of MMP-dependent and -independent collective cancer cell invasion. Physical Biology. 8: 015010. PMID 21301056 DOI: 10.1088/1478-3975/8/1/015010  0.449
2011 Friedl P, Wolf K, Lammerding J. Nuclear mechanics during cell migration. Current Opinion in Cell Biology. 23: 55-64. PMID 21109415 DOI: 10.1016/J.Ceb.2010.10.015  0.441
2011 Friedl P. MS1-1: Imaging Cancer Invasion In Vivo: Mechanisms and Implications for Therapy. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Ms1-1  0.382
2011 Ilina O, Bakker GJ, Vasaturo A, Hoffman RM, Friedl P. Erratum: Two-photon laser-generated microtracks in 3D collagen lattices: Principles of MMP-dependent and -independent collective cancer cell invasion (Physical Biology (2011) 8 (015010)) Physical Biology. 8: 29501. DOI: 10.1088/1478-3975/8/2/029501  0.386
2011 Friedl P, Wolf K, Lammerding J. Corrigendum to “Nuclear mechanics during cell migration” [Curr. Opin. Cell Biol. 23 (2011) 55–64] Current Opinion in Cell Biology. 23: 253. DOI: 10.1016/J.Ceb.2011.03.001  0.432
2010 Khalil AA, Friedl P. Determinants of leader cells in collective cell migration. Integrative Biology : Quantitative Biosciences From Nano to Macro. 2: 568-74. PMID 20886167 DOI: 10.1039/C0Ib00052C  0.506
2010 Friedl P, Zallen JA. Dynamics of cell-cell and cell-matrix interactions in morphogenesis, regeneration and cancer. Current Opinion in Cell Biology. 22: 557-9. PMID 20850290 DOI: 10.1016/J.Ceb.2010.08.024  0.471
2010 Weigelin B, Friedl P. A three-dimensional organotypic assay to measure target cell killing by cytotoxic T lymphocytes. Biochemical Pharmacology. 80: 2087-91. PMID 20849829 DOI: 10.1016/J.Bcp.2010.09.004  0.444
2010 Storim J, Bröcker EB, Friedl P. A dynamic immunological synapse mediates homeostatic TCR-dependent and -independent signaling. European Journal of Immunology. 40: 2741-50. PMID 20821730 DOI: 10.1002/Eji.201040575  0.422
2010 Meierjohann S, Hufnagel A, Wende E, Kleinschmidt MA, Wolf K, Friedl P, Gaubatz S, Schartl M. MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation. Molecular Cancer. 9: 201. PMID 20667128 DOI: 10.1186/1476-4598-9-201  0.405
2010 Belletti B, Pellizzari I, Berton S, Fabris L, Wolf K, Lovat F, Schiappacassi M, D'Andrea S, Nicoloso MS, Lovisa S, Sonego M, Defilippi P, Vecchione A, Colombatti A, Friedl P, et al. p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling Molecular and Cellular Biology. 30: 2229-2240. PMID 20194624 DOI: 10.1128/Mcb.00723-09  0.414
2010 Friedl P, Wolf K. Plasticity of cell migration: a multiscale tuning model. The Journal of Cell Biology. 188: 11-9. PMID 19951899 DOI: 10.1083/Jcb.200909003  0.489
2010 Schmidt S, Friedl P. Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms. Cell and Tissue Research. 339: 83-92. PMID 19921267 DOI: 10.1007/S00441-009-0892-9  0.435
2010 Friedl P. Deep collective cancer invasion: Breaking radioresistance by anti-integrin therapy Clinical Cancer Research. 16. DOI: 10.1158/Diag-10-Pl7-1  0.344
2010 Storim J, Bröcker EB, Friedl P. Cover Picture: Eur. J. Immunol. 10/10 European Journal of Immunology. 40. DOI: 10.1002/Eji.201090056  0.354
2009 Ilina O, Friedl P. Mechanisms of collective cell migration at a glance. Journal of Cell Science. 122: 3203-8. PMID 19726629 DOI: 10.1242/Jcs.036525  0.45
2009 Wolf K, Alexander S, Schacht V, Coussens LM, von Andrian UH, van Rheenen J, Deryugina E, Friedl P. Collagen-based cell migration models in vitro and in vivo. Seminars in Cell & Developmental Biology. 20: 931-41. PMID 19682592 DOI: 10.1016/J.Semcdb.2009.08.005  0.434
2009 Berton S, Belletti B, Wolf K, Canzonieri V, Lovat F, Vecchione A, Colombatti A, Friedl P, Baldassarre G. The tumor suppressor functions of p27kip1 include control of the mesenchymal/amoeboid transition Molecular and Cellular Biology. 29: 5031-5045. PMID 19596789 DOI: 10.1128/Mcb.00144-09  0.364
2009 Friedl P, Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nature Reviews. Molecular Cell Biology. 10: 445-57. PMID 19546857 DOI: 10.1038/Nrm2720  0.473
2009 Imle A, Polzer B, Alexander S, Klein CA, Friedl P. Genomic instability of micronucleated cells revealed by single-cell comparative genomic hybridization. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 562-8. PMID 19405114 DOI: 10.1002/Cyto.A.20733  0.371
2009 Andresen V, Alexander S, Heupel WM, Hirschberg M, Hoffman RM, Friedl P. Infrared multiphoton microscopy: subcellular-resolved deep tissue imaging. Current Opinion in Biotechnology. 20: 54-62. PMID 19324541 DOI: 10.1016/J.Copbio.2009.02.008  0.321
2009 Friedl P. Dynamic imaging of cancer invasion and metastasis: principles and preclinical applications. Clinical & Experimental Metastasis. 26: 269-71. PMID 19229643 DOI: 10.1007/S10585-009-9243-1  0.311
2009 Friedl P, Wolf K. Proteolytic interstitial cell migration: a five-step process. Cancer Metastasis Reviews. 28: 129-35. PMID 19153672 DOI: 10.1007/S10555-008-9174-3  0.458
2009 Wolf K, Friedl P. Mapping proteolytic cancer cell-extracellular matrix interfaces. Clinical & Experimental Metastasis. 26: 289-98. PMID 18600304 DOI: 10.1007/S10585-008-9190-2  0.468
2008 Alexander S, Koehl GE, Hirschberg M, Geissler EK, Friedl P. Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model. Histochemistry and Cell Biology. 130: 1147-54. PMID 18987875 DOI: 10.1007/S00418-008-0529-1  0.434
2008 Friedl P, Wolf K. Tube travel: the role of proteases in individual and collective cancer cell invasion. Cancer Research. 68: 7247-9. PMID 18794108 DOI: 10.1158/0008-5472.Can-08-0784  0.454
2008 Friedl P, Weigelin B. Interstitial leukocyte migration and immune function. Nature Immunology. 9: 960-9. PMID 18711433 DOI: 10.1038/Ni.F.212  0.381
2008 Muessel MJ, Scott KS, Friedl P, Bradding P, Wardlaw AJ. CCL11 and GM-CSF differentially use the Rho GTPase pathway to regulate motility of human eosinophils in a three-dimensional microenvironment. Journal of Immunology (Baltimore, Md. : 1950). 180: 8354-60. PMID 18523302 DOI: 10.4049/Jimmunol.180.12.8354  0.354
2008 Belletti B, Nicoloso MS, Schiappacassi M, Berton S, Lovat F, Wolf K, Canzonieri V, D'Andrea S, Zucchetto A, Friedl P, Colombatti A, Baldassarre G. Stathmin activity influences sarcoma cell shape, motility, and metastatic potential Molecular Biology of the Cell. 19: 2003-2013. PMID 18305103 DOI: 10.1091/Mbc.E07-09-0894  0.468
2008 Friedl P. Individual and collective cancer cell invasion Ejc Supplements. 6: 62. DOI: 10.1016/S1359-6349(08)71412-5  0.417
2007 Friedl P, Wolf K, von Andrian UH, Harms G. Biological second and third harmonic generation microscopy. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 4.15. PMID 18228516 DOI: 10.1002/0471143030.Cb0415S34  0.348
2007 Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nature Cell Biology. 9: 893-904. PMID 17618273 DOI: 10.1038/Ncb1616  0.454
2007 Oostingh GJ, Schlickum S, Friedl P, Schön MP. Impaired induction of adhesion molecule expression in immortalized endothelial cells leads to functional defects in dynamic interactions with lymphocytes. The Journal of Investigative Dermatology. 127: 2253-8. PMID 17460735 DOI: 10.1038/Sj.Jid.5700828  0.403
2006 Wolf K, Friedl P. Molecular mechanisms of cancer cell invasion and plasticity. The British Journal of Dermatology. 154: 11-5. PMID 16712711 DOI: 10.1111/J.1365-2133.2006.07231.X  0.496
2006 Hartmann A, Boukamp P, Friedl P. Confocal reflection imaging of 3D fibrin polymers. Blood Cells, Molecules & Diseases. 36: 191-3. PMID 16488165 DOI: 10.1016/J.Bcmd.2005.12.033  0.378
2005 Friedl P. Cell fusion: new mechanisms of plasticity in cancer? The Lancet. Oncology. 6: 916-8. PMID 16321755 DOI: 10.1016/S1470-2045(05)70439-3  0.376
2005 Friedl P, den Boer AT, Gunzer M. Tuning immune responses: diversity and adaptation of the immunological synapse. Nature Reviews. Immunology. 5: 532-45. PMID 15999094 DOI: 10.1038/Nri1647  0.362
2005 Wolf K, Friedl P. Functional imaging of pericellular proteolysis in cancer cell invasion. Biochimie. 87: 315-20. PMID 15781318 DOI: 10.1016/J.Biochi.2004.10.016  0.485
2004 Mayer C, Maaser K, Daryab N, Zänker KS, Bröcker EB, Friedl P. Release of cell fragments by invading melanoma cells. European Journal of Cell Biology. 83: 709-15. PMID 15679115 DOI: 10.1078/0171-9335-00394  0.476
2004 Friedl P, Storim J. Diversity in immune-cell interactions: states and functions of the immunological synapse. Trends in Cell Biology. 14: 557-67. PMID 15450978 DOI: 10.1016/J.Tcb.2004.09.005  0.395
2004 Friedl P, Hegerfeldt Y, Tusch M. Collective cell migration in morphogenesis and cancer. The International Journal of Developmental Biology. 48: 441-9. PMID 15349818 DOI: 10.1387/Ijdb.041821Pf  0.512
2004 Uhlenbrock K, Eberth A, Herbrand U, Daryab N, Stege P, Meier F, Friedl P, Collard JG, Ahmadian MR. The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism. Journal of Cell Science. 117: 4863-71. PMID 15340013 DOI: 10.1242/Jcs.01367  0.502
2004 Friedl P. Dynamic imaging of cellular interactions with extracellular matrix. Histochemistry and Cell Biology. 122: 183-90. PMID 15258769 DOI: 10.1007/S00418-004-0682-0  0.432
2004 Gunzer M, Weishaupt C, Hillmer A, Basoglu Y, Friedl P, Dittmar KE, Kolanus W, Varga G, Grabbe S. A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo. Blood. 104: 2801-9. PMID 15256430 DOI: 10.1182/Blood-2004-03-1193  0.424
2004 Friedl P. Prespecification and plasticity: shifting mechanisms of cell migration. Current Opinion in Cell Biology. 16: 14-23. PMID 15037300 DOI: 10.1016/J.Ceb.2003.11.001  0.484
2004 Friedl P, Bröcker EB. Reconstructing leukocyte migration in 3D extracellular matrix by time-lapse videomicroscopy and computer-assisted tracking. Methods in Molecular Biology (Clifton, N.J.). 239: 77-90. PMID 14573911 DOI: 10.1385/1-59259-435-2:77  0.312
2003 Friedl P, Wolf K. Proteolytic and non-proteolytic migration of tumour cells and leucocytes. Biochemical Society Symposium. 277-85. PMID 14587300 DOI: 10.1042/Bss0700277  0.489
2003 Wolf K, Müller R, Borgmann S, Bröcker EB, Friedl P. Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases. Blood. 102: 3262-3269. PMID 12855577 DOI: 10.1182/Blood-2002-12-3791  0.425
2003 Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms Nature Reviews Cancer. 3: 362-374. PMID 12724734 DOI: 10.1038/Nrc1075  0.458
2003 Wolf K, Mazo I, Leung H, Engelke K, von Andrian UH, Deryugina EI, Strongin AY, Bröcker EB, Friedl P. Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. The Journal of Cell Biology. 160: 267-77. PMID 12527751 DOI: 10.1083/Jcb.200209006  0.42
2002 Friedl P, Bröcker EB. TCR triggering on the move: diversity of T-cell interactions with antigen-presenting cells. Immunological Reviews. 186: 83-89. PMID 12234364 DOI: 10.1034/J.1600-065X.2002.18608.X  0.393
2001 Friedl P, Gunzer M. Interaction of T cells with APCs: The serial encounter model Trends in Immunology. 22: 187-191. PMID 11274922 DOI: 10.1016/S1471-4906(01)01869-5  0.376
2001 Friedl P, Borgmann S, Bröcker E. Amoeboid leukocyte crawling through extracellular matrix: lessons from the Dictyostelium paradigm of cell movement. Journal of Leukocyte Biology. 70: 491-509. DOI: 10.1189/Jlb.70.4.491  0.425
2000 Friedl P, Brocker EB. T cell migration in three-dimensional extracellular matrix: guidance by polarity and sensations. Developmental Immunology. 7: 249-266. PMID 11097216 DOI: 10.1155/2000/56473  0.454
2000 Gunzer M, Schäfer A, Borgmann S, Grabbe S, Zänker KS, Bröcker EB, Kämpgen E, Friedl P. Antigen Presentation in Extracellular Matrix: Interactions of T Cells with Dendritic Cells Are Dynamic, Short Lived, and Sequential Immunity. 13: 323-332. PMID 11021530 DOI: 10.1016/S1074-7613(00)00032-7  0.413
2000 Friedl P, Bröcker EB. The biology of cell locomotion within three-dimensional extracellular matrix. Cellular and Molecular Life Sciences. 57: 41-64. PMID 10949580 DOI: 10.1007/S000180050498  0.517
2000 Gunzer M, Friedl P, Niggemann B, Bröcker E, Kämpgen E, Zänker KS. Migration of dendritic cells within 3-D collagen lattices is dependent on tissue origin, state of maturation, and matrix structure and is maintained by proinflammatory cytokines Journal of Leukocyte Biology. 67: 622-629. PMID 10811001 DOI: 10.1002/Jlb.67.5.622  0.449
1999 Maaser K, Wolf K, Klein CE, Niggemann B, Zänker KS, Bröcker EB, Friedl P. Functional Hierarchy of Simultaneously Expressed Adhesion Receptors: Integrin α2β1 but Not CD44 Mediates MV3 Melanoma Cell Migration and Matrix Reorganization within Three-dimensional Hyaluronan-containing Collagen Matrices Molecular Biology of the Cell. 10: 3067-3079. PMID 10512851 DOI: 10.1091/Mbc.10.10.3067  0.388
1998 Friedl P, Zänker KS, Bröcker EB. Cell migration strategies in 3‐D extracellular matrix: Differences in morphology, cell matrix interactions, and integrin function Microscopy Research and Technique. 43: 369-378. PMID 9858334 DOI: 10.1002/(Sici)1097-0029(19981201)43:5<369::Aid-Jemt3>3.0.Co;2-6  0.478
1998 Friedl P, Bröcker EB, Zänker KS. Integrins, cell matrix interactions and cell migration strategies: fundamental differences in leukocytes and tumor cells. Cell Adhesion and Communication. 6: 225-236. PMID 9823473 DOI: 10.3109/15419069809004478  0.483
1998 Nikolai G, Niggemann B, Werner M, Zänker KS, Friedl P. Direct and rapid induction of migration in human CD4+ T lymphocytes within three-dimensional collagen matrices mediated by signalling via CD3 and/or CD2. Immunology. 95: 62-68. PMID 9767458 DOI: 10.1046/J.1365-2567.1998.00571.X  0.355
1998 Friedl P, Entschladen F, Conrad C, Niggemann B, Zänker KS. CD4+ T lymphocytes migrating in three‐dimensional collagen lattices lack focal adhesions and utilize β1 integrin‐independent strategies for polarization, interaction with collagen fibers and locomotion European Journal of Immunology. 28: 2331-2343. PMID 9710211 DOI: 10.1002/(Sici)1521-4141(199808)28:08<2331::Aid-Immu2331>3.0.Co;2-C  0.397
1998 Friedl P, Bröcker E, Zänker KS. Integrins, cell matrix interactions and cell migration strategies: Fundamental differences in leukocytes and tumor cells Journal of Dermatological Science. 16. DOI: 10.1016/S0923-1811(98)83738-9  0.484
1998 Tusch M, Hegerfeldt Y, Muradali S, Bröcker E, Friedl P. Invasion and migration of clustered cells from primary tumor explants: Differential expression and function of β1 integrins Journal of Dermatological Science. 16. DOI: 10.1016/S0923-1811(98)83191-5  0.356
1997 Niggemann B, Maaser K, Lü H, Kroczek R, Zänker KS, Friedl P. Locomotory phenotypes of human tumor cell lines and T lymphocytes in a three-dimensional collagen lattice Cancer Letters. 118: 173-180. PMID 9459207 DOI: 10.1016/S0304-3835(97)00328-5  0.465
1997 Dorner B, Müller S, Entschladen F, Schröder JM, Franke P, Kraft R, Friedl P, Clark-Lewis I, Kroczek RA. Purification, structural analysis, and function of natural ATAC, a cytokine secreted by CD8(+) T cells. Journal of Biological Chemistry. 272: 8817-8823. PMID 9079718 DOI: 10.1074/Jbc.272.13.8817  0.306
1997 Domer B, Müller S, Entschladen F, Friedl P, Schröder JM, Clark-Lewis I, Kroczek RA. Biochemical and functional characterization of ATAC, a new cytokine secreted by CD8+ T cells Immunology Letters. 56: 274-275. DOI: 10.1016/S0165-2478(97)86100-7  0.302
1995 Friedl P, Noble PB, Walton PA, Chauvin PJ, Tabah RJ, Zänker KS. Invasion and migration of coordinated cell clusters in rhabdomyosarcoma and other head and neck tumors in a 3-D collagen matrix Journal of Cancer Research and Clinical Oncology. 121. DOI: 10.1007/Bf02572216  0.386
1993 Friedl P, Noble PB, Zänker KS. Lymphocyte locomotion in three-dimensional collagen gels comparison of three quantitative methods for analysing cell trajectories Journal of Immunological Methods. 165: 157-165. PMID 7901283 DOI: 10.1016/0022-1759(93)90341-4  0.347
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