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Matthew Meyerson, M.D. Ph.D. - Publications

Affiliations: 
Medical Oncology Dana-Farber Cancer Institute, Boston, MA, United States 
Area:
oncology, genomics
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Year Citation  Score
2023 Tarantino P, Gupta H, Hughes ME, Files J, Strauss S, Kirkner G, Feeney AM, Li Y, Garrido-Castro AC, Barroso-Sousa R, Bychkovsky BL, DiLascio S, Sholl L, MacConaill L, Lindeman N, ... ... Meyerson M, et al. Author Correction: Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer. Nature Communications. 14: 8321. PMID 38097580 DOI: 10.1038/s41467-023-44124-y  0.765
2023 Tan KT, Slevin MK, Leibowitz ML, Garrity-Janger M, Li H, Meyerson M. Neotelomeres and Telomere-Spanning Chromosomal Arm Fusions in Cancer Genomes Revealed by Long-Read Sequencing. Biorxiv : the Preprint Server For Biology. PMID 38077026 DOI: 10.1101/2023.11.30.569101  0.317
2023 Pulice JL, Meyerson M. Dosage amplification dictates oncogenic regulation by the lineage factor in lung adenocarcinoma. Biorxiv : the Preprint Server For Biology. PMID 37994369 DOI: 10.1101/2023.10.26.563996  0.302
2023 Gibson WJ, Sadagopan A, Shoba VM, Choudhary A, Meyerson M, Schreiber SL. Bifunctional Small Molecules That Induce Nuclear Localization and Targeted Transcriptional Regulation. Journal of the American Chemical Society. PMID 37992275 DOI: 10.1021/jacs.3c06179  0.788
2023 Tarantino P, Gupta H, Hughes ME, Files J, Strauss S, Kirkner G, Feeney AM, Li Y, Garrido-Castro AC, Barroso-Sousa R, Bychkovsky BL, DiLascio S, Sholl L, MacConaill L, Lindeman N, ... ... Meyerson M, et al. Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer. Nature Communications. 14: 7496. PMID 37980405 DOI: 10.1038/s41467-023-43324-w  0.78
2023 Groves A, Ward A, Li YY, Lazo de la Vega L, Nag A, Forrest SJ, Gupta HV, Thorner AR, Meyerson M, Kamihara J, Cherniack AD, Janeway KA. Loss of heterozygosity does not occur in BRCA1/2 mutant pediatric solid and central nervous system tumors. Pediatric Blood & Cancer. e30643. PMID 37596911 DOI: 10.1002/pbc.30643  0.793
2023 Singh H, Keller RB, Kapner KS, Dilly J, Raghavan S, Yuan C, Cohen EF, Tolstorukov M, Andrews E, Brais LK, da Silva A, Perez K, Rubinson DA, Surana R, Giannakis M, ... ... Meyerson M, et al. Oncogenic drivers and therapeutic vulnerabilities in KRAS wild-type pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37463056 DOI: 10.1158/1078-0432.CCR-22-3930  0.771
2023 Gibson WJ, Sadagopan A, Shoba VM, Choudhary A, Meyerson M, Schreiber SL. Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation. Biorxiv : the Preprint Server For Biology. PMID 37461636 DOI: 10.1101/2023.07.07.548101  0.788
2023 Shih J, Sarmashghi S, Zhakula-Kostadinova N, Zhang S, Georgis Y, Hoyt SH, Cuoco MS, Gao GF, Spurr LF, Berger AC, Ha G, Rendo V, Shen H, Meyerson M, Cherniack AD, et al. Cancer aneuploidies are shaped primarily by effects on tumour fitness. Nature. PMID 37380777 DOI: 10.1038/s41586-023-06266-3  0.656
2023 Alessi JV, Wang X, Elkrief A, Ricciuti B, Li YY, Gupta H, Spurr LF, Rizvi H, Luo J, Pecci F, Lamberti G, Recondo G, Venkatraman D, Di Federico A, Gandhi MM, ... ... Meyerson ML, et al. Impact of aneuploidy and chromosome 9p loss on tumor immune microenvironment and immune checkpoint inhibitor efficacy in non-small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 37247843 DOI: 10.1016/j.jtho.2023.05.019  0.772
2022 Gao GF, Oh C, Saksena G, Deng D, Westlake LC, Hill BA, Reich M, Schumacher SE, Berger AC, Carter SL, Cherniack AD, Meyerson M, Tabak B, Beroukhim R, Getz G. Tangent normalization for somatic copy-number inference in cancer genome analysis. Bioinformatics (Oxford, England). PMID 36040167 DOI: 10.1093/bioinformatics/btac586  0.665
2022 Zhou M, Ko M, Hoge AC, Luu K, Liu Y, Russell ML, Hannon WW, Zhang Z, Carrot-Zhang J, Beroukhim R, Van Allen EM, Choudhury AD, Nelson PS, Freedman M, Taplin ME, ... Meyerson M, et al. Patterns of structural variation define prostate cancer across disease states. Jci Insight. PMID 35943799 DOI: 10.1172/jci.insight.161370  0.801
2022 Zhang Z, Golomb L, Meyerson M. Correction: Functional Genomic Analysis of CDK4 and CDK6 Gene Dependency across Human Cancer Cell Lines. Cancer Research. 82: 2808. PMID 35919992 DOI: 10.1158/0008-5472.CAN-22-2038  0.327
2022 Zhang Z, Golomb L, Meyerson M. Functional genomic analysis of CDK4 and CDK6 gene dependency across human cancer cell lines. Cancer Research. PMID 35395071 DOI: 10.1158/0008-5472.CAN-21-2428  0.333
2022 Gannon HS, Zou T, Kiessling MK, Gao GF, Cai D, Choi PS, Ivan AP, Buchumenski I, Berger AC, Goldstein JT, Cherniack AD, Vazquez F, Tsherniak A, Levanon EY, Hahn WC, ... Meyerson M, et al. Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Nature Communications. 13: 1894. PMID 35365656 DOI: 10.1038/s41467-022-29467-2  0.483
2021 Aquilanti E, Kageler L, Wen PY, Meyerson M. Telomerase as a therapeutic target in glioblastoma. Neuro-Oncology. PMID 34473298 DOI: 10.1093/neuonc/noab203  0.332
2021 Tan KT, Kim H, Carrot-Zhang J, Zhang Y, Kim WJ, Kugener G, Wala JA, Howard TP, Chi YY, Beroukhim R, Li H, Ha G, Alper SL, Perlman EJ, Mullen EA, ... ... Meyerson M, et al. Haplotype-resolved germline and somatic alterations in renal medullary carcinomas. Genome Medicine. 13: 114. PMID 34261517 DOI: 10.1186/s13073-021-00929-4  0.786
2021 Wu Z, Zhou J, Zhang X, Zhang Z, Xie Y, Liu JB, Ho ZV, Panda A, Qiu X, Cejas P, Cañadas I, Akarca FG, McFarland JM, Nagaraja AK, Goss LB, ... ... Meyerson M, et al. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nature Genetics. PMID 33972779 DOI: 10.1038/s41588-021-00859-2  0.575
2021 Cleary JM, Raghavan S, Wu Q, Li YY, Spurr LF, Gupta HV, Rubinson DA, Fetter IJ, Hornick JL, Nowak JA, Siravegna G, Goyal L, Shi L, Brais LK, Loftus M, ... ... Meyerson M, et al. FGFR2 Extracellular Domain In-Frame Deletions are Therapeutically Targetable Genomic Alterations that Function as Oncogenic Drivers in Cholangiocarcinoma. Cancer Discovery. PMID 33926920 DOI: 10.1158/2159-8290.CD-20-1669  0.804
2021 Zhou J, Wu Z, Zhang Z, Goss L, McFarland J, Nagaraja A, Xie Y, Gu S, Peng K, Zeng Y, Zhang X, Long H, Nakagawa H, Rustgi A, Diehl JA, ... Meyerson M, et al. Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma. Gut. PMID 33789967 DOI: 10.1136/gutjnl-2020-323276  0.579
2021 Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, ... ... Meyerson M, et al. Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway. Cell Reports. 34: 108784. PMID 33626341 DOI: 10.1016/j.celrep.2021.108784  0.605
2021 Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, ... Meyerson M, et al. Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway. Cell Reports. 34: 108707. PMID 33535033 DOI: 10.1016/j.celrep.2021.108707  0.666
2020 Zhang X, Meyerson M. Illuminating the noncoding genome in cancer. Nature Cancer. 1: 864-872. PMID 35121955 DOI: 10.1038/s43018-020-00114-3  0.369
2020 Carrot-Zhang J, Soca-Chafre G, Patterson N, Thorner AR, Nag A, Watson J, Genovese G, Rodriguez J, Gelbard MK, Corrales-Rodriguez L, Mitsuishi Y, Ha G, Campbell JD, Oxnard GR, Arrieta O, ... Meyerson M, et al. Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populations. Cancer Discovery. PMID 33268447 DOI: 10.1158/2159-8290.CD-20-1165  0.339
2020 Spurr LF, Touat M, Taylor AM, Dubuc AM, Shih J, Meredith DM, Pisano WV, Meyerson ML, Ligon KL, Cherniack AD, Li YY, Beroukhim R. Quantification of aneuploidy in targeted sequencing data using ASCETS. Bioinformatics (Oxford, England). PMID 33247715 DOI: 10.1093/bioinformatics/btaa980  0.606
2020 Meyerson M. Bacterial invaders drive CRC progression. Science Signaling. 13. PMID 32788340 DOI: 10.1126/Scisignal.Abc4218  0.358
2020 Koga Y, Song H, Chalmers ZR, Newberg J, Kim E, Carrot-Zhang J, Piou D, Polak P, Abdulkadir SA, Ziv E, Meyerson M, Frampton GM, Campbell JD, Huang FW. Genomic Profiling of Prostate Cancers from Men with African and European Ancestry. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32651179 DOI: 10.1158/1078-0432.Ccr-19-4112  0.354
2020 Corsello SM, Nagari RT, Spangler RD, Rossen J, Kocak M, Bryan JG, Humeidi R, Peck D, Wu X, Tang AA, Wang VM, Bender SA, Lemire E, Narayan R, Montgomery P, ... ... Meyerson M, et al. Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling. Nature Cancer. 1: 235-248. PMID 32613204 DOI: 10.1038/s43018-019-0018-6  0.645
2020 Zhang Z, Mäkinen N, Kasai Y, Kim GE, Diosdado B, Nakakura E, Meyerson M. Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors. Genes, Chromosomes & Cancer. PMID 32291827 DOI: 10.1002/Gcc.22850  0.357
2020 Parsons HA, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo CC, Li T, Fleharty M, Kirkner GJ, Rotem D, Cohen O, Yu F, Fitarelli-Kiehl M, ... ... Meyerson M, et al. Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32170028 DOI: 10.1158/1078-0432.Ccr-19-3005  0.342
2020 Pleguezuelos-Manzano C, Puschhof J, Huber AR, van Hoeck A, Wood HM, Nomburg J, Gurjao C, Manders F, Dalmasso G, Stege PB, Paganelli FL, Geurts MH, Beumer J, Mizutani T, van der Linden R, ... Meyerson M, et al. Mutational signature in colorectal cancer caused by genotoxic pks E. coli. Nature. PMID 32106218 DOI: 10.1038/S41586-020-2080-8  0.425
2020 Calabrese C, Davidson NR, Demircioğlu D, Fonseca NA, He Y, Kahles A, Lehmann KV, Liu F, Shiraishi Y, Soulette CM, Urban L, Greger L, Li S, Liu D, ... Meyerson M, et al. Genomic basis for RNA alterations in cancer. Nature. 578: 129-136. PMID 32025019 DOI: 10.1038/S41586-020-1970-0  0.49
2020 Wu X, Schnitzler GR, Gao GF, Diamond B, Baker AR, Kaplan B, Williamson K, Westlake L, Lorrey S, Lewis TA, Garvie CW, Lange M, Hayat S, Seidel H, Doench J, ... Meyerson M, et al. Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. The Journal of Biological Chemistry. PMID 32005668 DOI: 10.1074/Jbc.Ra119.011191  0.419
2020 Cleary JM, Raghavan S, Li YY, Spurr L, Wu Q, Shi L, Brais LK, Odhiambo Z, Goyal L, Patel AK, Shinagare AB, Clancy TE, Shapiro G, Cerami E, Sellers WR, ... ... Meyerson M, et al. Therapeutic targeting of extracellular FGFR2 activating deletions in intrahepatic cholangiocarcinoma. Journal of Clinical Oncology. 38: 567-567. DOI: 10.1200/Jco.2020.38.4_Suppl.567  0.664
2020 Parsons HA, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo C, Li T, Fleharty M, Kirkner G, Rotem D, Cohen O, Hughes M, Rosenberg S, ... ... Meyerson M, et al. Abstract P5-01-03: Ultrasensitive detection of minimal residual disease in patients treated for breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-01-03  0.394
2020 Nomburg J, Bullman S, Collisson E, Mushi B, Seleka M, Vaske C, Newton Y, Radenbuagh A, Akoko L, DeCaprio JA, Meyerson M, Mmbaga EJ, Loon KV. Abstract B06: Investigating the microbial etiology of Tanzanian esophageal squamous cell carcinoma Cancer Research. 80. DOI: 10.1158/1538-7445.Mvc2020-B06  0.445
2020 Taylor AM, Jain S, Shih J, Cherniack AD, Beroukhim R, Meyerson M. Abstract A44: Functional models of chromosome arm-level aneuploidies in cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-A44  0.676
2020 Freeman SS, Sade-Feldman M, Kim J, Stewart C, Ravi A, Arniella M, Yizhak K, Leshchiner I, Elagina L, Spiro O, Livitz D, Rosebrock D, Aguet F, Carrot-Zhang J, Gonye A, ... ... Meyerson M, et al. Abstract 6670: Combined signals from tumor and immune cells predict outcomes of checkpoint inhibition in melanoma Immunology. 80: 6670-6670. DOI: 10.1158/1538-7445.Am2020-6670  0.361
2020 Li YY, Cleary JM, Raghavan S, Spurr LF, Wu Q, Shi L, Brais LK, Loftus M, Goyal L, Patel AK, Shinagare AB, Clancy TE, Shapiro G, Cerami E, Sellers WR, ... ... Meyerson M, et al. Abstract 1097: FGFR2 in-frame indels: A novel targetable alteration in intrahepatic cholangiocarcinoma Tumor Biology. DOI: 10.1158/1538-7445.Am2020-1097  0.6
2019 Llabata P, Mitsuishi Y, Choi PS, Cai D, Francis JM, Torres-Diz M, Udeshi ND, Golomb L, Wu Z, Zhou J, Svinkina T, Aguilera-Jimenez E, Liu Y, Carr SA, Sanchez-Cespedes M, Meyerson M, et al. Multi-Omics analysis identifies MGA as a negative regulator of the MYC pathway in lung adenocarcinoma. Molecular Cancer Research : McR. PMID 31862696 DOI: 10.1158/1541-7786.Mcr-19-0657  0.439
2019 Chen H, Carrot-Zhang J, Zhao Y, Hu H, Freeman SS, Yu S, Ha G, Taylor AM, Berger AC, Westlake L, Zheng Y, Zhang J, Ramachandran A, Zheng Q, Pan Y, ... ... Meyerson M, et al. Genomic and immune profiling of pre-invasive lung adenocarcinoma. Nature Communications. 10: 5472. PMID 31784532 DOI: 10.1038/S41467-019-13460-3  0.422
2019 Lewis TA, de Waal L, Wu X, Youngsaye W, Wengner A, Kopitz C, Lange M, Gradl S, Ellermann M, Lienau P, Schreiber SL, Greulich H, Meyerson M. Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing. Acs Medicinal Chemistry Letters. 10: 1537-1542. PMID 31749907 DOI: 10.1021/Acsmedchemlett.9B00360  0.5
2019 Kim M, Mun H, Sung CO, Cho EJ, Jeon HJ, Chun SM, Jung DJ, Shin TH, Jeong GS, Kim DK, Choi EK, Jeong SY, Taylor AM, Jain S, Meyerson M, et al. Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening. Nature Communications. 10: 3991. PMID 31488816 DOI: 10.1038/S41467-019-11867-6  0.421
2019 Stover EH, Baco MB, Cohen O, Li YY, Christie EL, Bagul M, Goodale A, Lee Y, Pantel S, Rees MG, Wei G, Presser AG, Gelbard MK, Zhang W, Zervantonakis IK, ... ... Meyerson M, et al. Pooled genomic screens identify anti-apoptotic genes as targetable mediators of chemotherapy resistance in ovarian cancer. Molecular Cancer Research : McR. PMID 31462500 DOI: 10.1158/1541-7786.Mcr-18-1243  0.347
2019 Zou T, Meyerson M. Circulating Tumor DNA Provides a Sneak Peek into Treatment Responses in Non-Small Cell Lung Cancer. Cancer Research. 79: 1038-1040. PMID 30877100 DOI: 10.1158/0008-5472.Can-19-0231  0.415
2019 Hayes TK, Luo F, Cohen O, Goodale AB, Lee Y, Pantel S, Bagul M, Piccioni F, Root DE, Garraway LA, Meyerson M, Johannessen CM. A functional landscape of resistance to MEK1/2 and CDK4/6 inhibition in NRAS mutant melanoma. Cancer Research. PMID 30819666 DOI: 10.1158/0008-5472.Can-18-2711  0.316
2019 Jin C, Lagoudas GK, Zhao C, Bullman S, Bhutkar A, Hu B, Ameh S, Sandel D, Liang XS, Mazzilli S, Whary MT, Meyerson M, Germain R, Blainey PC, Fox JG, et al. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells. Cell. PMID 30712876 DOI: 10.1016/J.Cell.2018.12.040  0.56
2019 Cai D, Choi PS, Gelbard M, Meyerson M. Identification and characterization of oncogenic SOS1 mutations in lung adenocarcinoma. Molecular Cancer Research : McR. PMID 30635434 DOI: 10.1158/1541-7786.Mcr-18-0316  0.448
2019 Stover EH, Baco MB, Cohen O, Li Y, Christie E, Bagul M, Goodale A, Lee Y, Pantel S, Rees M, Wei G, Presser A, Zervantonakis I, Bhola P, Ryan J, ... Meyerson M, et al. Abstract AP14: POOLED GENOMIC SCREENS IDENTIFY ANTI-APOPTOTIC GENES AS MEDIATORS OF CHEMOTHERAPY RESISTANCE IN OVARIAN CANCER Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Ap14  0.364
2019 Goldstein JT, Berger AC, Strathdee CA, Meyerson M. Abstract 1026: Oncogenic alterations in FGFR3 and ERBB2 lead to ligand-independent activation of PPARG in bladder cancer Cancer Research. 79: 1026-1026. DOI: 10.1158/1538-7445.Am2019-1026  0.471
2019 Taylor A, Shih J, Ha G, Gao G, Zhang X, Berger A, Cherniack A, Beroukhim R, Meyerson M. MS12.02 Genomic and Functional Approaches to Understanding Cancer Aneuploidy Journal of Thoracic Oncology. 14: S179. DOI: 10.1016/J.Jtho.2019.08.355  0.656
2018 Bandopadhayay P, Meyerson M. Landscapes of childhood tumours. Nature. 555: 316-317. PMID 32094694 DOI: 10.1038/D41586-018-01648-4  0.622
2018 Gannon HS, Zou T, Kiessling MK, Gao GF, Cai D, Choi PS, Ivan AP, Buchumenski I, Berger AC, Goldstein JT, Cherniack AD, Vazquez F, Tsherniak A, Levanon EY, Hahn WC, Meyerson M, et al. Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Nature Communications. 9: 5450. PMID 30575730 DOI: 10.1038/S41467-018-07824-4  0.594
2018 Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, ... ... Meyerson M, et al. Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. PMID 30559381 DOI: 10.1038/S41586-018-0722-X  0.741
2018 Choudhury AD, Werner L, Francini E, Wei XX, Ha G, Freeman SS, Rhoades J, Reed SC, Gydush G, Rotem D, Lo C, Taplin ME, Harshman LC, Zhang Z, O'Connor EP, ... ... Meyerson M, et al. Tumor fraction in cell-free DNA as a biomarker in prostate cancer. Jci Insight. 3. PMID 30385733 DOI: 10.1172/Jci.Insight.122109  0.522
2018 Chen Y, Jones KL, Anastassiadis K, Kranz A, Stewart AF, Grembecka J, Meyerson M, Ernst P. Distinct Pathways Affected by Menin versus MLL1/MLL2 in MLL-rearranged Acute Myeloid Leukemia. Experimental Hematology. PMID 30315824 DOI: 10.1016/J.Exphem.2018.10.001  0.316
2018 Hamada T, Zhang X, Mima K, Bullman S, Sukawa Y, Nowak JA, Kosumi K, Masugi Y, Twombly TS, Cao Y, Song M, Liu L, da Silva A, Shi Y, Gu M, ... ... Meyerson M, et al. Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status. Cancer Immunology Research. PMID 30228205 DOI: 10.1158/2326-6066.Cir-18-0174  0.34
2018 Giacomelli AO, Yang X, Lintner RE, McFarland JM, Duby M, Kim J, Howard TP, Takeda DY, Ly SH, Kim E, Gannon HS, Hurhula B, Sharpe T, Goodale A, Fritchman B, ... Meyerson M, et al. Mutational processes shape the landscape of TP53 mutations in human cancer. Nature Genetics. PMID 30224644 DOI: 10.1038/S41588-018-0204-Y  0.588
2018 Ben-David U, Siranosian B, Ha G, Tang H, Oren Y, Hinohara K, Strathdee CA, Dempster J, Lyons NJ, Burns R, Nag A, Kugener G, Cimini B, Tsvetkov P, Maruvka YE, ... Meyerson M, et al. Genetic and transcriptional evolution alters cancer cell line drug response. Nature. PMID 30089904 DOI: 10.1038/S41586-018-0409-3  0.811
2018 Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, ... ... Meyerson M, et al. Genotype-targeted local therapy of glioma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30082399 DOI: 10.1073/Pnas.1805751115  0.314
2018 Walker MA, Pedamallu CS, Ojesina AI, Bullman S, Sharpe T, Whelan CW, Meyerson M. GATK PathSeq: A customizable computational tool for the discovery and identification of microbial sequences in libraries from eukaryotic hosts. Bioinformatics (Oxford, England). PMID 29982281 DOI: 10.1093/Bioinformatics/Bty501  0.308
2018 Yurgelun MB, Chittenden AB, Morales-Oyarvide V, Rubinson DA, Dunne RF, Kozak MM, Qian ZR, Welch MW, Brais LK, Da Silva A, Bui JL, Yuan C, Li T, Li W, Masuda A, ... Meyerson ML, et al. Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 29961768 DOI: 10.1038/S41436-018-0009-5  0.501
2018 Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, ... ... Meyerson ML, et al. Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nature Medicine. PMID 29955182 DOI: 10.1038/S41591-018-0097-4  0.728
2018 Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, ... ... Meyerson ML, et al. Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nature Medicine. PMID 29955181 DOI: 10.1038/S41591-018-0098-3  0.745
2018 Viswanathan SR, Nogueira MF, Buss CG, Krill-Burger JM, Wawer MJ, Malolepsza E, Berger AC, Choi PS, Shih J, Taylor AM, Tanenbaum B, Pedamallu CS, Cherniack AD, Tamayo P, Strathdee CA, ... Meyerson M, et al. Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. Nature Genetics. PMID 29955178 DOI: 10.1038/S41588-018-0155-3  0.798
2018 Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, ... Meyerson M, et al. Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing. Cell. PMID 29909985 DOI: 10.1016/J.Cell.2018.05.036  0.814
2018 Shen H, Shih J, Hollern DP, Wang L, Bowlby R, Tickoo SK, Thorsson V, Mungall AJ, Newton Y, Hegde AM, Armenia J, Sánchez-Vega F, Pluta J, Pyle LC, Mehra R, ... ... Meyerson M, et al. Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Reports. 23: 3392-3406. PMID 29898407 DOI: 10.1016/J.Celrep.2018.05.039  0.426
2018 Guo G, Raje NS, Seifer C, Kloeber J, Isenhart R, Ha G, Yee AJ, O'Donnell EK, Tai YT, Richardson PG, Bianchi G, Laubach JP, Warren D, Gemme E, Voisine J, ... ... Meyerson M, et al. Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing. Leukemia. PMID 29749395 DOI: 10.1038/S41375-018-0115-Z  0.345
2018 Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, ... ... Meyerson ML, et al. Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nature Medicine. PMID 29713087 DOI: 10.1038/S41591-018-0016-8  0.774
2018 Bockorny B, Rusan M, Chen W, Liao RG, Li Y, Piccioni F, Wang J, Tan L, Thorner AR, Li T, Zhang Y, Miao CH, Ovesen T, Shapiro GI, Kwiatkowski DJ, ... Meyerson M, et al. RAS-MAPK reactivation facilitates acquired resistance in FGFR1-amplified lung cancer and underlies a rationale for upfront FGFR-MEK blockade. Molecular Cancer Therapeutics. PMID 29654068 DOI: 10.1158/1535-7163.Mct-17-0464  0.634
2018 Bullman S, Zou T, Meyerson M. Mechanistic Insights into Transmissible Cancers of Mammals. Cancer Cell. 33: 543-544. PMID 29634941 DOI: 10.1016/J.Ccell.2018.03.019  0.364
2018 Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, ... Meyerson M, et al. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 173: 321-337.e10. PMID 29625050 DOI: 10.1016/J.Cell.2018.03.035  0.453
2018 Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ, Cherniack AD, Beroukhim R, Meyerson M. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer Cell. PMID 29622463 DOI: 10.1016/J.Ccell.2018.03.007  0.711
2018 Bandopadhayay P, Meyerson M. Landscapes of childhood tumours. Nature. 555: 316-317. PMID 29542703 DOI: 10.1038/d41586-018-01648-4  0.467
2018 Wala JA, Bandopadhayay P, Greenwald N, O'Rourke R, Sharpe T, Stewart C, Schumacher S, Li Y, Weischenfeldt J, Yao X, Nusbaum C, Campbell P, Getz G, Meyerson M, Zhang CZ, et al. SvABA: genome-wide detection of structural variants and indels by local assembly. Genome Research. PMID 29535149 DOI: 10.1101/Gr.221028.117  0.814
2018 Cho J, Kim S, Du J, Meyerson M. Autophosphorylation of the C-terminal domain is not required for oncogenic transformation by lung-cancer derived EGFR mutants. International Journal of Cancer. PMID 29464683 DOI: 10.1002/Ijc.31332  0.385
2018 MacConaill LE, Burns RT, Nag A, Coleman HA, Slevin MK, Giorda K, Light M, Lai K, Jarosz M, McNeill MS, Ducar MD, Meyerson M, Thorner AR. Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing. Bmc Genomics. 19: 30. PMID 29310587 DOI: 10.1186/S12864-017-4428-5  0.308
2018 Choudhury AD, Werner L, Ha G, Freeman S, Rhoades J, Reed S, Gydush G, Rotem D, Lo C, Taplin M, Harshman LC, Zhang Z, O'Connor EP, Boehm J, Getz G, ... Meyerson M, et al. Tumor fraction in circulating free DNA as a biomarker of disease dynamics in metastatic prostate cancer. Journal of Clinical Oncology. 36: 195-195. DOI: 10.1200/Jco.2018.36.6_Suppl.195  0.547
2018 Freeman SS, Lin Z, Ha G, Leshchiner I, Rhoades J, Livitz D, Rosebrock D, Reed SC, Gydush G, Lo C, Rotem D, Choudhury AD, Stover DG, Parsons HA, Boehm JS, ... ... Meyerson M, et al. Abstract LB-225: Liquid biopsies identify trunk mutations and reflect multiple tumors in a patient Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-225  0.416
2018 Lewis TA, Waal Ld, Wu X, Ellerman M, Kopitz C, Wengner A, Eis K, Lange M, Tersteegen A, Lienau P, Greulich H, Meyerson M. Abstract 5880: Small-molecule modulators of PDE3/SLFN12 to kill cancer cells Cancer Research. 78: 5880-5880. DOI: 10.1158/1538-7445.Am2018-5880  0.39
2018 Bullman S, Pedamallu CS, Sicinska E, Clancy T, Ogino S, Tabernero J, Fuchs C, Hahn WC, Nuciforo P, Meyerson M. Abstract 5129: Fusobacterium and co-occurring microbes in primary and metastatic colorectal cancer Cancer Research. 78: 5129-5129. DOI: 10.1158/1538-7445.Am2018-5129  0.594
2018 Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La K, Dimitriadoy S, Liu DL, Kantheti HS, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, ... Meyerson M, et al. Abstract 3302: The molecular landscape of oncogenic signaling pathways in The Cancer Genome Atlas Cancer Research. 78: 3302-3302. DOI: 10.1158/1538-7445.Am2018-3302  0.47
2018 Taylor AM, Zhang X, Shih J, Ha G, Gao GF, Berger AC, Cherniack AD, Beroukhim R, Meyerson M. Abstract 3002: Genome engineering approaches to generate models of chromosome arm-level cancer aneuploidy Cancer Research. 78: 3002-3002. DOI: 10.1158/1538-7445.Am2018-3002  0.669
2018 Ben-David U, Siranosian B, Ha G, Tang H, Lyons NJ, Burns R, Nag A, Cimini B, Tsvetkov P, Tubelli AA, Wong B, Thorner AR, Bittker J, Meyerson M, Beroukhim R, et al. Abstract 214: Genetic and transcriptional instability alters cell line drug response Cancer Research. 78: 214-214. DOI: 10.1158/1538-7445.Am2018-214  0.798
2017 Berger AH, Brooks AN, Wu X, Shrestha Y, Chouinard C, Piccioni F, Bagul M, Kamburov A, Imielinski M, Hogstrom L, Zhu C, Yang X, Pantel S, Sakai R, Watson J, ... Meyerson M, et al. High-throughput Phenotyping of Lung Cancer Somatic Mutations. Cancer Cell. 32: 884. PMID 29232558 DOI: 10.1016/j.ccell.2017.11.008  0.325
2017 Bullman S, Pedamallu CS, Sicinska E, Clancy TE, Zhang X, Cai D, Neuberg D, Huang K, Guevara F, Nelson T, Chipashvili O, Hagan T, Walker M, Ramachandran A, Diosdado B, ... Meyerson M, et al. Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer. Science (New York, N.Y.). PMID 29170280 DOI: 10.1126/Science.Aal5240  0.576
2017 Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, ... ... Meyerson M, et al. Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. Nature Communications. 8: 1324. PMID 29109393 DOI: 10.1038/S41467-017-00965-Y  0.422
2017 Qian ZR, Rubinson DA, Nowak JA, Morales-Oyarvide V, Dunne RF, Kozak MM, Welch MW, Brais LK, Da Silva A, Li T, Li W, Masuda A, Yang J, Shi Y, Gu M, ... ... Meyerson M, et al. Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma. Jama Oncology. PMID 29098284 DOI: 10.1001/Jamaoncol.2017.3420  0.459
2017 Rusan M, Li K, Li Y, Christensen CL, Abraham BJ, Kwiatkowski N, Buczkowski KA, Bockorny B, Chen T, Li S, Rhee K, Zhang H, Chen W, Terai H, Tavares T, ... ... Meyerson M, et al. Suppression of adaptive responses to targeted cancer therapy by transcriptional repression. Cancer Discovery. PMID 29054992 DOI: 10.1158/2159-8290.Cd-17-0461  0.626
2017 Robertson AG, Kim J, Al-Ahmadie H, Bellmunt J, Guo G, Cherniack AD, Hinoue T, Laird PW, Hoadley KA, Akbani R, Castro MAA, Gibb EA, Kanchi RS, Gordenin DA, Shukla SA, ... ... Meyerson M, et al. Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell. PMID 28988769 DOI: 10.1016/J.Cell.2017.09.007  0.393
2017 Zhang X, Choi PS, Francis JM, Gao GF, Campbell JD, Ramachandran A, Mitsuishi Y, Ha G, Shih J, Vazquez F, Tsherniak A, Taylor AM, Zhou J, Wu Z, Berger AC, ... Meyerson M, et al. Somatic super-enhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor. Cancer Discovery. PMID 28963353 DOI: 10.1158/2159-8290.Cd-17-0532  0.633
2017 Goldstein JT, Berger AC, Shih J, Duke FF, Furst L, Kwiatkowski DJ, Cherniack AD, Meyerson M, Strathdee CA. Genomic activation of PPARG reveals a candidate therapeutic axis in bladder cancer. Cancer Research. PMID 28923856 DOI: 10.1158/0008-5472.Can-17-1701  0.469
2017 Holst F, Hoivik EA, Gibson WJ, Taylor-Weiner A, Schumacher SE, Asmann YW, Grossmann P, Trovik J, Necela BM, Thompson EA, Meyerson M, Beroukhim R, Salvesen HB, Cherniack AD. Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth. Scientific Reports. 7: 46873. PMID 28664899 DOI: 10.1038/srep46873  0.729
2017 Rheinbay E, Parasuraman P, Grimsby J, Tiao G, Engreitz JM, Kim J, Lawrence MS, Taylor-Weiner A, Rodriguez-Cuevas S, Rosenberg M, Hess J, Stewart C, Maruvka YE, Stojanov P, Cortes ML, ... Meyerson M, et al. Recurrent and functional regulatory mutations in breast cancer. Nature. PMID 28658208 DOI: 10.1038/Nature22992  0.625
2017 Lu X, Peled N, Greer J, Wu W, Choi P, Berger AH, Wong S, Jen KY, Seo Y, Hann B, Brooks A, Meyerson M, Collisson EA. MET exon 14 mutation encodes an actionable therapeutic target in lung adenocarcinoma. Cancer Research. PMID 28522754 DOI: 10.1158/0008-5472.Can-16-1944  0.435
2017 Imielinski M, Guo G, Meyerson M. Insertions and Deletions Target Lineage-Defining Genes in Human Cancers. Cell. PMID 28089356 DOI: 10.1016/J.Cell.2016.12.025  0.479
2017 Stover DG, Parsons HA, Ha G, Freeman S, Barry WT, Guo H, Gydush G, Reed S, Rhoades J, Rotem D, Hughes ME, Krop IE, Tolaney SM, Wagle N, Getz G, Meyerson M, et al. Genome-wide copy number analysis of cell-free DNA from patients with chemotherapy-resistant metastatic triple-negative breast cancer. Journal of Clinical Oncology. 35: 1092-1092. DOI: 10.1200/Jco.2017.35.15_Suppl.1092  0.428
2017 Chapuy B, Stewart C, Dunford A, Kim J, Kamburow A, Redd RA, Lawrence M, Roemer MGM, Li A, Ziepert M, Staiger AM, Wala J, Ducar MD, Leshchiner I, Rheinbay E, ... ... Meyerson M, et al. Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome Blood. 130: 38-38. DOI: 10.1182/Blood.V130.Suppl_1.38.38  0.751
2017 Meyers RM, Aguirre AJ, Weir BA, Vazquez F, Zhang C, Ben-David U, Cook A, Ha G, Harrington WF, Doshi M, Gill S, Xu H, Ali LD, Jiang G, Pantel S, ... Meyerson M, et al. Abstract B39: Genomic copy number alterations introduce a gene-independent viability bias in CRISPR-Cas9 knock-out screens of cancer cell lines Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-B39  0.602
2017 Li J, Choi P, Chaffer C, Labella K, Kim JW, Doench J, Dai C, Giacomelli A, Ly SH, Hwang J, Hong A, Ilic N, Gjoerup O, Meyerson M, Brooks A, et al. Abstract A36: Genome-scale ORF screening to identify modulators of the epithelial-to-mesenchymal transition Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-A36  0.651
2017 Nishihara R, Chan AT, Mu JX, Giannakis M, Mima K, Qian ZR, Bullman S, Kostic AD, Huttenhower C, Garrett W, Giovannucci EL, Meyerson M, Garraway LA, Fuchs CS, Ogino S. Abstract PR01:Fusobacterium nucleatumand mutational landscape of colorectal cancer in whole-exome sequencing analysis Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-Pr01  0.429
2017 Amin S, Awadalla P, Biankin A, Boutros P, Brazma A, Brooks AN, Calabrese C, Chang D, Chateigner A, Chen K, Chong Z, Craft B, Creighton C, Demircioğlu D, Fonseca N, ... Meyerson M, et al. Abstract SY10-02: Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Sy10-02  0.396
2017 Burns RT, Hunter SS, Ducar MD, Thorner AR, Decaprio JA, Hummelen PV, Frieden A, Nag A, Coleman HA, Slevin MK, Clapp A, Drinan SD, McShane SR, Thai E, Shivdasani P, ... ... Meyerson M, et al. Abstract 562: Oncovirus detection and integration analysis from human tumor samples using targeted massively parallel sequencing Cancer Research. 77: 562-562. DOI: 10.1158/1538-7445.Am2017-562  0.324
2017 Li J, Choi P, Chaffer C, Labella K, Kim JW, Doench J, Dai C, Giacomelli A, Ly SH, Hwang J, Hong A, Ilic N, Gjoerup O, Meyerson M, Brooks A, et al. Abstract 5020: A genome-scale ORF screen reveals an alternative splicing program that regulates mesenchymal and stem-like cell states in breast cancer Cancer Research. 77: 5020-5020. DOI: 10.1158/1538-7445.Am2017-5020  0.646
2017 Gannon HS, Kiessling M, Vazquez F, Hahn W, Meyerson M. Abstract 4616: Exploring the role of interferon and innate immune regulators in outlier cancer cell line survival Cancer Research. 77: 4616-4616. DOI: 10.1158/1538-7445.Am2017-4616  0.587
2017 Mima K, Hamada T, Nishihara R, Nowak J, Qian ZR, Kosumi K, Giannakis M, Bullman S, Baba H, Huttenhower C, Garrett W, Chan A, Meyerson M, Fuchs C, Ogino S. Abstract 4560: Fusobacterium nucleatum and tumor immunity status according to microsatellite instability in colorectal cancer Cancer Research. 77: 4560-4560. DOI: 10.1158/1538-7445.Am2017-4560  0.367
2017 Taylor AM, Ha G, Shih J, Zhang X, Francis JM, Meyerson M. Abstract 409: Genome engineering to generate models of chromosome arm-level aneuploidies in lung carcinoma Cancer Research. 77: 409-409. DOI: 10.1158/1538-7445.Am2017-409  0.324
2017 Goldstein JT, Strathdee C, Duke F, Shih J, Meyerson M. Abstract 3627: Validation of PPARG and RXRA as drivers of bladder cancer Cancer Research. 77: 3627-3627. DOI: 10.1158/1538-7445.Am2017-3627  0.443
2017 Campbell J, Zhang X, Dhillon SS, Perdomo C, Mazzilli S, Geshalter Y, Liu G, Zhang S, Lin H, Vick J, Moy C, Monti S, Johnson E, Meyerson M, Dubinett S, et al. Abstract 3259: The genomic landscape of premalignant lung squamous cell carcinoma lesions Cancer Research. 77: 3259-3259. DOI: 10.1158/1538-7445.Am2017-3259  0.331
2017 Wu X, Lewis T, Waal Ld, Gao G, Zhang J, Schenone M, Garvie C, Diamond B, Lorrey S, Cherniack A, Corsello S, Burgin A, Golub T, Schreiber S, Meyerson M, et al. Abstract 2028: PDE3A modulation for cancer therapy Cancer Research. 77: 2028-2028. DOI: 10.1158/1538-7445.Am2017-2028  0.48
2017 Cai D, Choi P, Meyerson M. MA 06.14 Oncogenic SOS1 Mutations in Lung Adenocarcinoma Journal of Thoracic Oncology. 12: S1825. DOI: 10.1016/J.Jtho.2017.09.501  0.357
2017 Taylor A, Gavin H, Shih J, Zhang X, Campbell J, Andrew C, Meyerson M. Genome Engineering to Generate Models of Chromosome Arm-Level Aneuploidies in Lung Cancer Journal of Thoracic Oncology. 12: S1545. DOI: 10.1016/J.Jtho.2017.06.057  0.379
2017 Peled N, Lu X, Greer J, Wu W, Choi P, Berger A, Hann B, Meyerson M, Collisson E. P2.03b-042 MET exon 14 Mutations Encode a Hyperactive Kinase and Therapeutic Target in Lung Adenocarcinoma Journal of Thoracic Oncology. 12: S961. DOI: 10.1016/J.Jtho.2016.11.1323  0.36
2016 Pedamallu CS, Bhatt AS, Bullman S, Fowler S, Freeman SS, Durand J, Jung J, Duke F, Manzo V, Cai D, Ananthakrishnan A, Ojesina AI, Ramachandran A, Gevers D, Xavier RJ, ... ... Meyerson M, et al. Metagenomic Characterization of Microbial Communities In Situ Within the Deeper Layers of the Ileum in Crohn's Disease. Cellular and Molecular Gastroenterology and Hepatology. 2: 563-566.e5. PMID 28174737 DOI: 10.1016/J.Jcmgh.2016.05.011  0.524
2016 Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, ... Meyerson M, et al. Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas. Neuro-Oncology. PMID 28170043 DOI: 10.1093/Neuonc/Now235  0.752
2016 Beroukhim R, Zhang X, Meyerson M. Copy number alterations unmasked as enhancer hijackers. Nature Genetics. 49: 5-6. PMID 28029156 DOI: 10.1038/Ng.3754  0.663
2016 Sholl LM, Do K, Shivdasani P, Cerami E, Dubuc AM, Kuo FC, Garcia EP, Jia Y, Davineni P, Abo RP, Pugh TJ, van Hummelen P, Thorner AR, Ducar M, Berger AH, ... Meyerson M, et al. Institutional implementation of clinical tumor profiling on an unselected cancer population. Jci Insight. 1: e87062. PMID 27882345 DOI: 10.1172/Jci.Insight.87062  0.706
2016 Lohr JG, Kim S, Gould J, Knoechel B, Drier Y, Cotton MJ, Gray D, Birrer N, Wong B, Ha G, Zhang CZ, Guo G, Meyerson M, Yee AJ, Boehm JS, et al. Genetic interrogation of circulating multiple myeloma cells at single-cell resolution. Science Translational Medicine. 8: 363ra147. PMID 27807282 DOI: 10.1126/Scitranslmed.Aac7037  0.338
2016 Lin W, Francis JM, Li H, Gao X, Pedamallu CS, Ernst P, Meyerson M. Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets. Cancer Biology & Therapy. 0. PMID 27801610 DOI: 10.1080/15384047.2016.1250986  0.308
2016 Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, ... ... Meyerson M, et al. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. Cancer Cell. 30: 363. PMID 27505681 DOI: 10.1016/J.Ccell.2016.07.013  0.331
2016 Giannikou K, Malinowska IA, Pugh TJ, Yan R, Tseng YY, Oh C, Kim J, Tyburczy ME, Chekaluk Y, Liu Y, Alesi N, Finlay GA, Wu CL, Signoretti S, Meyerson M, et al. Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development. Plos Genetics. 12: e1006242. PMID 27494029 DOI: 10.1371/Journal.Pgen.1006242  0.606
2016 Berger AH, Brooks AN, Wu X, Shrestha Y, Chouinard C, Piccioni F, Bagul M, Kamburov A, Imielinski M, Hogstrom L, Zhu C, Yang X, Pantel S, Sakai R, Watson J, ... Meyerson M, et al. High-throughput Phenotyping of Lung Cancer Somatic Mutations. Cancer Cell. PMID 27478040 DOI: 10.1016/J.Ccell.2016.06.022  0.472
2016 Holst F, Hoivik EA, Gibson WJ, Taylor-Weiner A, Schumacher SE, Asmann YW, Grossmann P, Trovik J, Necela BM, Thompson EA, Meyerson M, Beroukhim R, Salvesen HB, Cherniack AD. Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth. Scientific Reports. 6: 27960. PMID 27338572 DOI: 10.1038/Srep27960  0.746
2016 Aguirre AJ, Meyers RM, Weir BA, Vazquez F, Zhang CZ, Ben-David U, Cook A, Ha G, Harrington WF, Doshi MB, Kost-Alimova M, Gill S, Xu H, Ali LD, Jiang G, ... ... Meyerson M, et al. Genomic copy number dictates a gene-independent cell response to CRISPR-Cas9 targeting. Cancer Discovery. PMID 27260156 DOI: 10.1158/2159-8290.Cd-16-0154  0.756
2016 Holst F, Hoivik EA, Gibson WJ, Taylor-Weiner A, Schumacher SE, Asmann YW, Grossmann P, Trovik J, Necela BM, Thompson EA, Meyerson M, Beroukhim R, Salvesen HB, Cherniack AD. Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth. Scientific Reports. 6: 25521. PMID 27160768 DOI: 10.1038/Srep25521  0.776
2016 Campbell JD, Alexandrov A, Kim J, Wala J, Berger AH, Pedamallu CS, Shukla SA, Guo G, Brooks AN, Murray BA, Imielinski M, Hu X, Ling S, Akbani R, Rosenberg M, ... ... Meyerson M, et al. Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas. Nature Genetics. PMID 27158780 DOI: 10.1038/Ng.3564  0.699
2016 Wala J, Zhang CZ, Meyerson M, Beroukhim R. VariantBam: filtering and profiling of next-generational sequencing data using region-specific rules. Bioinformatics (Oxford, England). PMID 27153727 DOI: 10.1093/Bioinformatics/Btw111  0.776
2016 Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, ... ... Meyerson M, et al. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 164: 550-563. PMID 26824661 DOI: 10.1016/J.Cell.2015.12.028  0.666
2016 de Velasco G, Miao D, Shukla S, Voss MH, Wu C, Murray B, Meyerson M, Signoretti S, Motzer RJ, Van Allen EM, Choueiri TK. Integrated genomic correlates of response to PD-1 inhibitor nivolumab in metastatic renal cell carcinoma (mRCC). Journal of Clinical Oncology. 34: 545-545. DOI: 10.1200/Jco.2016.34.2_Suppl.545  0.351
2016 Huynh MA, Maire CL, Abazeed M, Lam FC, Adams D, Pelton K, Pinnell N, Knoff DC, Korideck H, Hummelen PV, Thorner A, Wen PY, Ligon A, Floyd SR, Schreiber SL, ... Meyerson M, et al. Functional profiling of a glioblastoma (GBM) patient-derived cell line (PDCL) panel to identify cell-intrinsic differential radiation response. Journal of Clinical Oncology. 34: 2069-2069. DOI: 10.1200/Jco.2016.34.15_Suppl.2069  0.699
2016 Lohr JG, Kim S, Gould J, Knoechel B, Drier Y, Gray D, Birrer N, Wong B, Ha G, Zhang C, Guo G, Meyerson M, Yee A, Boehm J, Raje N, et al. Comprehensive Genetic Interrogation of Circulating Multiple Myeloma Cells at Single Cell Resolution Blood. 128: 800-800. DOI: 10.1182/Blood.V128.22.800.800  0.395
2016 Aguirre AJ, Shao W, Xu H, Weir B, Vazquez F, Meyers R, Zhang C, Doshi M, Cowley GS, Ewachiw T, Rasheed Z, Golub TR, Stegmaier K, Roberts CW, Garraway LA, Meyerson M, et al. Abstract PR05: Genome-scale CRISPR-Cas9 screening to identify essential genes and pathways in pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-Pr05  0.551
2016 Adalsteinsson VA, Ha G, Freeman S, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed S, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Cohen O, Oh C, Kim J, ... Meyerson M, et al. Abstract LB-136: High concordance of whole-exome sequencing of cell-free DNA and matched biopsies enables genomic discovery in metastatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-136  0.506
2016 Campbell JD, Perdomo C, Mazzilli S, Geshalter Y, Dhillon SS, Liu G, Zhang S, Lin H, Vick J, Moy C, Johnson E, Meyerson M, Platero S, Lenburg M, Reid M, et al. Abstract 895: Genomic characterization of premalignant lung squamous cell carcinoma lesions Cancer Research. 76: 895-895. DOI: 10.1158/1538-7445.Am2016-895  0.419
2016 Wang L, Gambe R, Fan J, Brooks AN, Sun J, Neuberg D, Kharchenko P, Meyerson M, Fleming MD, Ebert BL, Carrasco R, Wu CJ. Abstract 669: Compound heterozygous Sf3b1-K700E mutation and Atm deletion in B cells leads to CLL in mice Cancer Research. 76: 669-669. DOI: 10.1158/1538-7445.Am2016-669  0.418
2016 Berger AH, Brooks AN, Wu X, Shrestha Y, Chouinard C, Piccioni F, Bagul M, Kamburov A, Imielinski M, Hogstrom L, Zhu C, Yang X, Pantel S, Sakai R, Kaplan N, ... Meyerson M, et al. Abstract 4368: High-throughput phenotyping of lung cancer somatic mutations Cancer Research. 76: 4368-4368. DOI: 10.1158/1538-7445.Am2016-4368  0.5
2016 Pedamallu CS, Meyerson M, Ojesina A. Abstract 3301: Breast cancer subtypes have distinct microbial and immune cytolytic transcriptomic signatures Cancer Research. 76: 3301-3301. DOI: 10.1158/1538-7445.Am2016-3301  0.411
2016 Mehta RS, Mima K, Song M, Nishihara R, Cao Y, Qian ZR, Kostic A, Fung T, Sukawa Y, Garrett W, Huttenhower C, Meyerson M, Wu K, Meyerhardt J, Willett W, et al. 759 Diet and Risk of Colorectal Cancer According to Intratumoral Fusobacterium Nucleatum Levels Gastroenterology. 150: S154. DOI: 10.1016/S0016-5085(16)30614-X  0.312
2016 Wang L, Brooks A, Gambe R, Fan J, Sun J, Hergert S, Wan Y, Neuberg D, Kharchenko P, Meyerson M, Fleming M, Ebert B, Wu C. From Human Genetic to Mouse Model: SF3B1 Mutation and its Impact on Chronic Lymphocytic Leukemia Clinical Lymphoma Myeloma and Leukemia. 16: S52. DOI: 10.1016/J.Clml.2016.07.076  0.313
2015 Knoechel B, Bhatt A, Pan L, Pedamallu CS, Severson E, Gutierrez A, Dorfman DM, Kuo FC, Kluk M, Kung AL, Zweidler-McKay P, Meyerson M, Blacklow SC, DeAngelo DJ, Aster JC. Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case. Cold Spring Harbor Molecular Case Studies. 1: a000539. PMID 27148573 DOI: 10.1101/mcs.a000539  0.594
2015 Zhang X, Choi PS, Francis JM, Imielinski M, Watanabe H, Cherniack AD, Meyerson M. Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers. Nature Genetics. PMID 26656844 DOI: 10.1038/Ng.3470  0.499
2015 de Waal L, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, ... Meyerson M, et al. Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics. Nature Chemical Biology. PMID 26656089 DOI: 10.1038/Nchembio.1984  0.546
2015 Gannon HS, Kaplan N, Tsherniak A, Vazquez F, Weir BA, Hahn WC, Meyerson M. Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-targeted Therapy. Molecular Cancer Research : McR. PMID 26582713 DOI: 10.1158/1541-7786.Mcr-15-0321  0.602
2015 Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, ... ... Meyerson M, et al. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. The New England Journal of Medicine. PMID 26536169 DOI: 10.1056/Nejmoa1505917  0.675
2015 Shankar GM, Lelic N, Gill CM, Thorner AR, Van Hummelen P, Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D, Brody RI, Duhaime AC, Taylor MD, ... ... Meyerson M, et al. BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology. Acta Neuropathologica. PMID 26487540 DOI: 10.1007/S00401-015-1492-2  0.368
2015 Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, ... ... Meyerson M, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discovery. PMID 26410082 DOI: 10.1158/2159-8290.Cd-15-0369  0.755
2015 Terai H, Tan L, Beauchamp EM, Hatcher JM, Liu Q, Meyerson M, Gray NS, Hammerman PS. Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer. Acs Chemical Biology. PMID 26390252 DOI: 10.1021/Acschembio.5B00655  0.428
2015 Park E, Kim N, Ficarro SB, Zhang Y, Lee BI, Cho A, Kim K, Park AK, Park WY, Murray B, Meyerson M, Beroukhim R, Marto JA, Cho J, Eck MJ. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nature Structural & Molecular Biology. 22: 703-11. PMID 26280531 DOI: 10.1038/Nsmb.3074  0.629
2015 Xu C, Buczkowski KA, Zhang Y, Asahina H, Beauchamp EM, Terai H, Li YY, Meyerson M, Wong KK, Hammerman PS. NSCLC Driven by DDR2 Mutation is Sensitive to Dasatinib and JQ1 Combination Therapy. Molecular Cancer Therapeutics. PMID 26206333 DOI: 10.1158/1535-7163.Mct-15-0077  0.462
2015 Shankar GM, Francis JM, Rinne ML, Ramkissoon SH, Huang FW, Venteicher AS, Akama-Garren EH, Kang YJ, Lelic N, Kim JC, Brown LE, Charbonneau SK, Golby AJ, Sekhar Pedamallu C, Hoang MP, ... ... Meyerson M, et al. Rapid Intraoperative Molecular Characterization of Glioma. Jama Oncology. PMID 26181761 DOI: 10.1001/Jamaoncol.2015.0917  0.394
2015 Crago AM, Chmielecki J, Rosenberg M, O'Connor R, Byrne C, Wilder FG, Thorn K, Agius P, Kuk D, Socci ND, Qin LX, Meyerson M, Hameed M, Singer S. Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis. Genes, Chromosomes & Cancer. PMID 26171757 DOI: 10.1002/Gcc.22272  0.418
2015 Karpathakis A, Dibra H, Pipinikas C, Feber A, Morris T, Francis JM, Oukrif D, Mandair D, Pericleous M, Mohmaduvesh M, Serra S, Ogunbiyi O, Novelli M, Luong T, Asa SL, ... ... Meyerson M, et al. Prognostic impact of novel molecular subtypes of small intestinal neuroendocrine tumour. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26169971 DOI: 10.1158/1078-0432.Ccr-15-0373  0.423
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, ... ... Meyerson ML, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.782
2015 Zhang CZ, Spektor A, Cornils H, Francis JM, Jackson EK, Liu S, Meyerson M, Pellman D. Chromothripsis from DNA damage in micronuclei. Nature. 522: 179-84. PMID 26017310 DOI: 10.1038/Nature14493  0.42
2015 van de Wetering M, Francies HE, Francis JM, Bounova G, Iorio F, Pronk A, van Houdt W, van Gorp J, Taylor-Weiner A, Kester L, McLaren-Douglas A, Blokker J, Jaksani S, Bartfeld S, Volckman R, ... Meyerson M, et al. Prospective derivation of a living organoid biobank of colorectal cancer patients. Cell. 161: 933-45. PMID 25957691 DOI: 10.1016/J.Cell.2015.03.053  0.432
2015 Bambury RM, Bhatt AS, Riester M, Pedamallu CS, Duke F, Bellmunt J, Stack EC, Werner L, Park R, Iyer G, Loda M, Kantoff PW, Michor F, Meyerson M, Rosenberg JE. DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors. Bmc Cancer. 15: 242. PMID 25886454 DOI: 10.1186/S12885-015-1192-2  0.603
2015 Zhang CZ, Adalsteinsson VA, Francis J, Cornils H, Jung J, Maire C, Ligon KL, Meyerson M, Love JC. Calibrating genomic and allelic coverage bias in single-cell sequencing. Nature Communications. 6: 6822. PMID 25879913 DOI: 10.1038/Ncomms7822  0.378
2015 Pugh TJ, Banerji S, Meyerson M. Pugh et al. reply. Nature. 520: E12-4. PMID 25877207 DOI: 10.1038/Nature14266  0.436
2015 Arvey A, Ojesina AI, Pedamallu CS, Ballon G, Jung J, Duke F, Leoncini L, De Falco G, Bressman E, Tam W, Chadburn A, Meyerson M, Cesarman E. The tumor virus landscape of AIDS-related lymphomas. Blood. 125: e14-22. PMID 25827832 DOI: 10.1182/Blood-2014-11-599951  0.306
2015 Wilson FH, Johannessen CM, Piccioni F, Tamayo P, Kim JW, Van Allen EM, Corsello SM, Capelletti M, Calles A, Butaney M, Sharifnia T, Gabriel SB, Mesirov JP, Hahn WC, Engelman JA, ... Meyerson M, et al. A functional landscape of resistance to ALK inhibition in lung cancer. Cancer Cell. 27: 397-408. PMID 25759024 DOI: 10.1016/J.Ccell.2015.02.005  0.509
2015 Ramos AH, Lichtenstein L, Gupta M, Lawrence MS, Pugh TJ, Saksena G, Meyerson M, Getz G. Oncotator: cancer variant annotation tool. Human Mutation. 36: E2423-9. PMID 25703262 DOI: 10.1002/Humu.22771  0.628
2015 Arrieta O, Cardona AF, Martín C, Más-López L, Corrales-Rodríguez L, Bramuglia G, Castillo-Fernandez O, Meyerson M, Amieva-Rivera E, Campos-Parra AD, Carranza H, Gómez de la Torre JC, Powazniak Y, Aldaco-Sarvide F, Vargas C, et al. Updated Frequency of EGFR and KRAS Mutations in NonSmall-Cell Lung Cancer in Latin America: The Latin-American Consortium for the Investigation of Lung Cancer (CLICaP). Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 838-43. PMID 25634006 DOI: 10.1097/Jto.0000000000000481  0.389
2015 Chung TK, Van Hummelen P, Chan PK, Cheung TH, Yim SF, Yu MY, Ducar MD, Thorner AR, MacConaill LE, Doran G, Pedamallu CS, Ojesina AI, Wong RR, Wang VW, Freeman SS, ... ... Meyerson M, et al. Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women. International Journal of Cancer. Journal International Du Cancer. 137: 776-83. PMID 25626421 DOI: 10.1002/Ijc.29456  0.341
2015 Lin W, Watanabe H, Peng S, Francis JM, Kaplan N, Pedamallu CS, Ramachandran A, Agoston A, Bass AJ, Meyerson M. Dynamic epigenetic regulation by menin during pancreatic islet tumor formation. Molecular Cancer Research : McR. 13: 689-98. PMID 25537453 DOI: 10.1158/1541-7786.Mcr-14-0457  0.607
2015 Guo G, Chmielecki J, Goparaju C, Heguy A, Dolgalev I, Carbone M, Seepo S, Meyerson M, Pass HI. Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma. Cancer Research. 75: 264-9. PMID 25488749 DOI: 10.1158/0008-5472.Can-14-1008  0.43
2015 Abo RP, Ducar M, Garcia EP, Thorner AR, Rojas-Rudilla V, Lin L, Sholl LM, Hahn WC, Meyerson M, Lindeman NI, Van Hummelen P, MacConaill LE. BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers. Nucleic Acids Research. 43: e19. PMID 25428359 DOI: 10.1093/Nar/Gku1211  0.564
2015 Bellmunt J, Guo G, Mullane SA, Orsola A, Werner L, Van Hummelen P, Thorner A, Loda M, Choueiri TK, Barletta JA, Kwiatkowski DJ, Meyerson M, Van Allen EM. Genomic landscape of high-grade T1 micropapillary bladder tumors. Journal of Clinical Oncology. 33: 299-299. DOI: 10.1200/Jco.2015.33.7_Suppl.299  0.447
2015 Murray B, Albiges L, Van Allen EM, Cherniack A, Fay AP, Meyerson M, Choueiri TK. Precision medicine approach in kidney cancer: A pan renal cell carcinoma (RCC) study across three cancer genome atlas (TCGA) datasets for clinically relevant target identification. Journal of Clinical Oncology. 33: 4564-4564. DOI: 10.1200/Jco.2015.33.15_Suppl.4564  0.466
2015 Albiges L, Murray B, Brooks A, Cherniack A, Berger A, Creighton CJ, Ricketts C, Bottaro DP, Srinivasan R, Schmidt LS, Meyerson M, Spellman P, Linehan WM, Choueiri TK. Distinct MET alterations to induce a common phenotype and to define a MET-driven subset of papillary RCC: Results from the Cancer Genome Atlas (TCGA) Kidney Renal Papillary (KIRP) Working Group. Journal of Clinical Oncology. 33: 4521-4521. DOI: 10.1200/Jco.2015.33.15_Suppl.4521  0.438
2015 Wang L, Gambe R, Fan J, Wan Y, Brooks AN, Sun J, Obeng EA, Neuberg DS, Meyerson M, Fleming MD, Ebert BL, Carrasco RD, Wu CJ. Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function Blood. 126: 366-366. DOI: 10.1182/Blood.V126.23.366.366  0.366
2015 Berger A, Brooks A, Wu X, Hogstrom L, Tirosh I, Piccioni F, Bagul M, Zhu C, Shretha Y, Root D, Tamayo P, Sakai R, Wong B, Subramanian A, Golub T, Meyerson M, et al. Abstract PR12: High-throughput gene expression profiling as a generalizable assay for determination of mutation impact on gene function Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr12  0.462
2015 Berger AH, Kim E, Brooks A, Ilic N, Shrestha Y, Tseng Y, Wu X, Zou L, Kamburov A, Yang X, Zhu C, Keskula P, Seepo S, Hong A, Kantoff P, ... Meyerson M, et al. Abstract PR07: Towards precision functional genomics via next-generation functional mapping of cancer variants Cancer Research. 75: 957-957. DOI: 10.1158/1538-7445.Transcagen-Pr07  0.633
2015 Berger A, Brooks A, Wu X, Hogstrom L, Tirosh I, Piccioni F, Bagul M, Zhu C, Shretha Y, Root D, Tamayo P, Sakai R, Wong B, Subramanian A, Golub T, Meyerson M, et al. Abstract PR04: High-throughput gene expression profiling as a generalizable assay for determination of mutation impact on gene function Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr04  0.457
2015 Brooks AN, Ge Y, Chau K, Freeman SS, Saksena G, Pedamallu CS, Meyerson M. Abstract B2-21: Identification of somatic RNA splicing alterations in human cancers Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B2-21  0.487
2015 Berger A, Kim E, Brooks A, Shrestha Y, Tseng Y, Wu X, Ilic N, Zou L, Kamburov A, Yang X, Zhu C, Keskula P, Seepo S, Hong A, Doench J, ... ... Meyerson M, et al. Abstract 957: Towards precision functional genomics via next-generation functional mapping of cancer variants Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2015-957  0.531
2015 Brastianos PK, Carter SL, Santagata S, Taylor-Weiner A, Jones RT, Allen EV, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Cahill D, Curry WT, Dunn IF, Paek SH, Hummelen PV, ... ... Meyerson M, et al. Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations Brain. 75: 4727-4727. DOI: 10.1158/1538-7445.Am2015-4727  0.695
2015 Campbell J, Lathan C, Sholl L, Ducar M, Vega M, Lin L, Thorner A, Faris N, Hummelen Pv, Osarogiagbon R, Meyerson M, MacConaill L. Abstract 3886: Comparing the mutational landscape of African American and Caucasian lung cancers Cancer Research. 75: 3886-3886. DOI: 10.1158/1538-7445.Am2015-3886  0.407
2015 Abazeed M, Yard B, Adams D, Tamayo P, Hearn J, Chie EK, Schreiber S, Meyerson M, Peacock C, Hammerman P. Abstract 3315: Functional genomic profiling of lung adenocarcinoma identifies BRAF mutations as novel therapeutic targets Cancer Research. 75: 3315-3315. DOI: 10.1158/1538-7445.Am2015-3315  0.768
2015 Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, ... ... Meyerson M, et al. Abstract 2976: Comprehensive Pan-Genomic characterization of adrenocortical carcinoma Cancer Research. 75: 2976-2976. DOI: 10.1158/1538-7445.Am2015-2976  0.328
2015 Lin L, Abo R, Dolcen D, Paquette R, Laing A, Waal Ld, Thorner A, Ducar M, Ziaugra L, Wollison B, Breneiser M, Hahn W, Meyerson M, Hummelen PV, MacConaill L. Abstract 1115: Targeted RNA sequencing improves transcript analysis in cancer samples Cancer Research. 75: 1115-1115. DOI: 10.1158/1538-7445.Am2015-1115  0.541
2015 Waal Ld, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, ... Meyerson M, et al. Abstract C136: Identification of selective cancer cytotoxic modulators of phosphodiesterase 3a by predictive chemogenomics Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C136  0.542
2015 Park E, Kim N, Ficarro SB, Zhang Y, Lee BI, Cho A, Kim K, Park AKJ, Park WY, Murray B, Meyerson M, Beroukhim R, Marto JA, Cho J, Eck MJ. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6 Nature Structural and Molecular Biology. DOI: 10.1038/nsmb.3074  0.537
2015 Huynh M, Maire C, Abazeed M, Adams D, Pelton K, Pinnell N, Ramkissoon S, Korideck H, Van Hummelen P, Thorner A, Wen P, Ligon A, Schreiber S, Meyerson M, Ligon K, et al. Functional Profiling of a Glioblastoma (GBM) Patient-Derived Cell Line (PDCL) Panel Identifies Cell-Intrinsic Differential Radiation Response That Correlates With TP53 Mutations International Journal of Radiation Oncology*Biology*Physics. 93: E91-E92. DOI: 10.1016/J.Ijrobp.2015.07.779  0.644
2015 Abazeed M, Adams D, Hammerman P, Tamayo P, Yard B, Meyerson M, Schreiber S. Systematic Investigation of Genetic Vulnerabilities Across Cancer Cell Lines Reveals Lineage Specific Radiotherapeutic Determinants International Journal of Radiation Oncology*Biology*Physics. 93: S143-S144. DOI: 10.1016/J.Ijrobp.2015.07.340  0.707
2014 Karpathakis A, Feber A, Morris T, Dibra H, Pipinikas C, Oukrife D, Francis J, Mandair D, Toumpanakis C, Meyer T, Luong TV, Caplin M, Meyerson M, Beck S, Thirlwell C. 1133OMOLECULAR PROFILING OF SMALL INTESTINAL NEUROENDOCRINE TUMOURS. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv394. PMID 28171426 DOI: 10.1093/Annonc/Mdu345.2  0.305
2014 Sharifnia T, Rusu V, Piccioni F, Bagul M, Imielinski M, Cherniack AD, Pedamallu CS, Wong B, Wilson FH, Garraway LA, Altshuler D, Golub TR, Root DE, Subramanian A, Meyerson M. Genetic modifiers of EGFR dependence in non-small cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: 18661-6. PMID 25512530 DOI: 10.1073/Pnas.1412228112  0.393
2014 Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, ... ... Meyerson M, et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 15544-9. PMID 25313082 DOI: 10.1073/Pnas.1416074111  0.369
2014 Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, ... Meyerson M, et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell. 26: 319-30. PMID 25155756 DOI: 10.1016/J.Ccr.2014.07.014  0.478
2014 Tchaicha JH, Akbay EA, Altabef A, Mikse OR, Kikuchi E, Rhee K, Liao RG, Bronson RT, Sholl LM, Meyerson M, Hammerman PS, Wong KK. Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a Pan-FGFR inhibitor in a mouse model of NSCLC. Cancer Research. 74: 4676-84. PMID 25035393 DOI: 10.1158/0008-5472.Can-13-3218  0.443
2014 Wik E, Trovik J, Kusonmano K, Birkeland E, Raeder MB, Pashtan I, Hoivik EA, Krakstad C, Werner HM, Holst F, Mjøs S, Halle MK, Mannelqvist M, Mauland KK, Oyan AM, ... ... Meyerson M, et al. Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations. Gynecologic Oncology. 134: 599-606. PMID 24995579 DOI: 10.1016/J.Ygyno.2014.06.026  0.376
2014 Pugh TJ, Yu W, Yang J, Field AL, Ambrogio L, Carter SL, Cibulskis K, Giannikopoulos P, Kiezun A, Kim J, McKenna A, Nickerson E, Getz G, Hoffher S, Messinger YH, ... ... Meyerson M, et al. Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences. Oncogene. 33: 5295-302. PMID 24909177 DOI: 10.1038/Onc.2014.150  0.555
2014 Cho J, Bass AJ, Lawrence MS, Cibulskis K, Cho A, Lee SN, Yamauchi M, Wagle N, Pochanard P, Kim N, Park AK, Won J, Hur HS, Greulich H, Ogino S, ... Meyerson M, et al. Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab. Molecular Cancer. 13: 141. PMID 24894453 DOI: 10.1186/1476-4598-13-141  0.663
2014 Francis JM, Zhang CZ, Maire CL, Jung J, Manzo VE, Adalsteinsson VA, Homer H, Haidar S, Blumenstiel B, Pedamallu CS, Ligon AH, Love JC, Meyerson M, Ligon KL. EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing. Cancer Discovery. 4: 956-71. PMID 24893890 DOI: 10.1158/2159-8290.CD-13-0879  0.323
2014 Helman E, Lawrence MS, Stewart C, Sougnez C, Getz G, Meyerson M. Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing. Genome Research. 24: 1053-63. PMID 24823667 DOI: 10.1101/gr.163659.113  0.419
2014 Choi PS, Meyerson M. Targeted genomic rearrangements using CRISPR/Cas technology. Nature Communications. 5: 3728. PMID 24759083 DOI: 10.1038/Ncomms4728  0.404
2014 Lohr JG, Adalsteinsson VA, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis JM, Zhang CZ, Shalek AK, Satija R, Trombetta JJ, Lu D, Tallapragada N, Tahirova N, Kim S, ... Meyerson M, et al. Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nature Biotechnology. 32: 479-84. PMID 24752078 DOI: 10.1038/Nbt.2892  0.613
2014 Watanabe H, Brooks AN, Meyerson M. Breaking down RET breakpoints in lung adenocarcinoma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 590-2. PMID 24722148 DOI: 10.1097/Jto.0000000000000168  0.412
2014 Bhatt AS, Manzo VE, Pedamallu CS, Duke F, Cai D, Bienfang DC, Padera RF, Meyerson M, Docken WP. In search of a candidate pathogen for giant cell arteritis: sequencing-based characterization of the giant cell arteritis microbiome. Arthritis & Rheumatology (Hoboken, N.J.). 66: 1939-44. PMID 24644069 DOI: 10.1002/Art.38631  0.58
2014 Watanabe H, Ma Q, Peng S, Adelmant G, Swain D, Song W, Fox C, Francis JM, Pedamallu CS, DeLuca DS, Brooks AN, Wang S, Que J, Rustgi AK, Wong KK, ... ... Meyerson M, et al. SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. The Journal of Clinical Investigation. 124: 1636-45. PMID 24590290 DOI: 10.1172/Jci71545  0.624
2014 Imielinski M, Greulich H, Kaplan B, Araujo L, Amann J, Horn L, Schiller J, Villalona-Calero MA, Meyerson M, Carbone DP. Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma. The Journal of Clinical Investigation. 124: 1582-6. PMID 24569458 DOI: 10.1172/Jci72763  0.486
2014 Brooks AN, Choi PS, de Waal L, Sharifnia T, Imielinski M, Saksena G, Pedamallu CS, Sivachenko A, Rosenberg M, Chmielecki J, Lawrence MS, DeLuca DS, Getz G, Meyerson M. A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events. Plos One. 9: e87361. PMID 24498085 DOI: 10.1371/Journal.Pone.0087361  0.491
2014 Weinstein JN, Akbani R, Broom BM, Wang W, Verhaak RGW, McConkey D, Lerner S, Morgan M, Creighton CJ, Smith C, Cherniack AD, Kim J, Pedamallu CS, Noble MS, Al-Ahmadie HA, ... Meyerson M, et al. Comprehensive molecular characterization of urothelial bladder carcinoma Nature. 507: 315-322. PMID 24476821 DOI: 10.1038/Nature12965  0.834
2014 Berger AH, Imielinski M, Duke F, Wala J, Kaplan N, Shi GX, Andres DA, Meyerson M. Oncogenic RIT1 mutations in lung adenocarcinoma. Oncogene. 33: 4418-23. PMID 24469055 DOI: 10.1038/onc.2013.581  0.704
2014 Shern JF, Chen L, Chmielecki J, Wei JS, Patidar R, Rosenberg M, Ambrogio L, Auclair D, Wang J, Song YK, Tolman C, Hurd L, Liao H, Zhang S, Bogen D, ... Meyerson M, et al. Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors. Cancer Discovery. 4: 216-31. PMID 24436047 DOI: 10.1158/2159-8290.Cd-13-0639  0.472
2014 Lawrence MS, Stojanov P, Mermel CH, Robinson JT, Garraway LA, Golub TR, Meyerson M, Gabriel SB, Lander ES, Getz G. Discovery and saturation analysis of cancer genes across 21 tumour types. Nature. 505: 495-501. PMID 24390350 DOI: 10.1038/Nature12912  0.493
2014 Ojesina AI, Lichtenstein L, Freeman SS, Pedamallu CS, Imaz-Rosshandler I, Pugh TJ, Cherniack AD, Ambrogio L, Cibulskis K, Bertelsen B, Romero-Cordoba S, Treviño V, Vazquez-Santillan K, Guadarrama AS, Wright AA, ... ... Meyerson M, et al. Landscape of genomic alterations in cervical carcinomas. Nature. 506: 371-5. PMID 24390348 DOI: 10.1038/Nature12881  0.591
2014 Kim Y, Hammerman PS, Kim J, Yoon JA, Lee Y, Sun JM, Wilkerson MD, Pedamallu CS, Cibulskis K, Yoo YK, Lawrence MS, Stojanov P, Carter SL, McKenna A, Stewart C, ... Meyerson M, et al. Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 121-8. PMID 24323028 DOI: 10.1200/Jco.2013.50.8556  0.461
2014 Beauchamp EM, Woods BA, Dulak AM, Tan L, Xu C, Gray NS, Bass AJ, Wong KK, Meyerson M, Hammerman PS. Acquired resistance to dasatinib in lung cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss. Molecular Cancer Therapeutics. 13: 475-82. PMID 24296828 DOI: 10.1158/1535-7163.Mct-13-0817  0.661
2014 Chmielecki J, Meyerson M. DNA sequencing of cancer: what have we learned? Annual Review of Medicine. 65: 63-79. PMID 24274178 DOI: 10.1146/Annurev-Med-060712-200152  0.424
2014 Rosenberg JE, Kim J, Cherniack A, Sougnez C, Meyerson M, Getz G, Weinstein JN, Lerner SP, Kwiatkowski DJ. Somatic genomic alterations in urothelial cancer: Results of the Cancer Genome Atlas (TCGA) bladder cancer (BC) analysis. Journal of Clinical Oncology. 32: 285-285. DOI: 10.1200/Jco.2014.32.4_Suppl.285  0.512
2014 Karpathakis A, Dibra H, Morris T, Oukrife D, Pipinikas CP, Pearce K, Francis J, Pericleous M, Mandair D, Feber A, Toumpanakis C, Luong TV, Meyerson M, Caplin ME, Beck S, et al. Genome-wide DNA methylation profiling of gastrointestinal neuroendocrine tumors to identify hypermethylation of mTOR, Wnt, and Notch pathways in GI NET pathogenesis. Journal of Clinical Oncology. 32: 212-212. DOI: 10.1200/Jco.2014.32.3_Suppl.212  0.312
2014 Araujo LH, Amann J, Imielinski M, Greulich H, Meyerson M, Carbone DP. Oncogenic ARAF as a new driver in lung adenocarcinoma. Journal of Clinical Oncology. 32: 11034-11034. DOI: 10.1200/Jco.2014.32.15_Suppl.11034  0.39
2014 Rhee C, Manzo V, Shea T, Desjardins C, Auwera GVd, Young S, Riley AM, DeAngelo DJ, Baden LR, Gee J, Meyerson M, Klompas M, Yokoe D, Weiser L, Pedamallu CS, et al. Bacillus Cereus: A Leukemia-Specific, Neuroinvasive Pathogen? Blood. 124: 4145-4145. DOI: 10.1182/Blood.V124.21.4145.4145  0.581
2014 Berger AH, Brooks AN, Imielinski M, Cherniack A, Duke F, Kaplan N, Wala J, Meyerson M. Abstract PR08:NF1,MET, andRIT1mutations are RAS-pathway driver events in lung adenocarcinoma Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-Pr08  0.753
2014 Adalsteinsson VA, Lohr JG, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis J, Zhang C, Shalek AK, Satija R, Trombetta JT, Lu D, Tallapragada N, Tahirova NT, Kim S, ... Meyerson M, et al. Abstract 993: Whole exome sequencing of CTCs as a window into metastatic cancer Cancer Research. 74: 993-993. DOI: 10.1158/1538-7445.Am2014-993  0.628
2014 Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Sloan AE, Cohen ML, Meir EGV, Scarpace L, Laird PW, Weinstein JN, Lander E, ... Meyerson M, et al. Abstract 984: Alteration of the p53 pathway is associated with subclonal tumor progression in glioblastoma Cancer Research. 74: 984-984. DOI: 10.1158/1538-7445.Am2014-984  0.45
2014 Ojesina AI, Murray B, Bjorge L, Woie K, Krakstad C, Lichtenstein L, Pedamallu CS, Taylor-Weiner A, Freeman SS, Cherniack AD, Lawrence MS, Cibulskis K, Carter SL, Walline H, Carey TE, ... Meyerson M, et al. Abstract 4692: Relationships between somatic genomic alterations, tumor stage and progression-free survival in cervical cancer Cancer Research. 74: 4692-4692. DOI: 10.1158/1538-7445.Am2014-4692  0.449
2014 Imielinski M, Du C, Meyerson M. Abstract 4263: Identifying somatic mutation hotspots across protein family alignments Cancer Research. 74: 4263-4263. DOI: 10.1158/1538-7445.Am2014-4263  0.384
2014 Abazeed M, Adams D, Tamayo P, Meyerson M, Hammerman P, Schreiber S. Abstract 4259: The radiogenomic landscape of cancer Cancer Research. 74: 4259-4259. DOI: 10.1158/1538-7445.Am2014-4259  0.737
2014 Thorner AR, Sunkavalli A, Lin L, Jones RT, Schubert L, Ducar MD, Adusumilli R, Dolcen DN, Ziaugra L, Lepine J, MacConaill LE, Hahn WC, Meyerson M, Hummelen PV. Abstract 3583: Reducing GC-bias and improving coverage distribution in Illumina sequencing using the Kapa Biosystems library construction method Cancer Research. 74: 3583-3583. DOI: 10.1158/1538-7445.Am2014-3583  0.523
2014 Kim Y, Hammerman PS, Kim J, Getz G, Meyerson M, Park K. Abstract 1526: Integrative and comparative genomic analysis of East-Asian lung squamous cell carcinomas Cancer Research. 74: 1526-1526. DOI: 10.1158/1538-7445.Am2014-1526  0.469
2014 Watanabe H, Ma Q, Peng S, Adelmant G, Swain D, Song W, Fox C, Francis JM, Pedamallu CS, Deluca DS, Brooks AN, Que J, Rustgi AK, Wong K, Ligon KL, ... ... Meyerson M, et al. Abstract 1391: SOX2-p63 interaction and genomic co-localization in squamous cell carcinomas Cancer Research. 74: 1391-1391. DOI: 10.1158/1538-7445.Am2014-1391  0.388
2014 Yasuda H, Park E, Yun CH, Sng NJ, Lucena-Araujo AR, Yeo WL, Huberman MS, Cohen DW, Nakayama S, Ishioka K, Yamaguchi N, Hanna M, Oxnard GR, Lathan CS, Moran T, ... ... Meyerson M, et al. Structural, biochemical, and clinical characterization of Epidermal Growth Factor Receptor (EGFR) exon 20 insertion mutations in lung cancer (Science Translational Medicine (2014) 6, (225er1)) Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.3008733  0.383
2014 Bhatt AS, Manzo VE, Pedamallu C, Duke F, Bienfang DC, Docken WP, Padera RF, Meyerson M. P2. In search of a candidate pathogen for GCA: sequencing based characterization of the GCA microbiome Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu210.002  0.548
2014 Kim H, Zheng S, Amini S, Virk S, Mikkelsen T, Brat D, Sougnez C, Muller F, Hu J, Sloan A, Cohen M, Van Meir E, Scarpace L, Lander E, Gabriel S, ... ... Meyerson M, et al. GE-17 * ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA Neuro-Oncology. 16: v100-v100. DOI: 10.1093/Neuonc/Nou256.17  0.422
2014 Verhaak RGW, Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, ... ... Meyerson M, et al. THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA Neuro-Oncology. 16: iii3-iii3. DOI: 10.1093/Neuonc/Nou206.10  0.424
2014 Abazeed M, Xu C, Adams D, Tamayo P, Loeffler J, Suh J, Meyerson M, Wong K, Hammerman P. NRF2 Is a Novel Oncogene and Biomarker of Therapeutic Resistance in Non-Small Cell Lung Cancer International Journal of Radiation Oncology*Biology*Physics. 90: S53. DOI: 10.1016/J.Ijrobp.2014.08.252  0.667
2014 Abazeed M, Xu C, Adams D, Tamayo P, Loeffler J, Suh J, Meyerson M, Wong K, Hammerman P. NRF2 Is a Novel Oncogene and Biomarker of Therapeutic Resistance in Non-Small Cell Lung Cancer International Journal of Radiation Oncology*Biology*Physics. 90: S104-S105. DOI: 10.1016/J.Ijrobp.2014.05.516  0.656
2014 Abazeed M, Adams D, Tamayo P, Yard B, Loeffler J, Suh J, Meyerson M, Hammerman P, Schreiber S. The Radiogenomic Landscape of Cancer International Journal of Radiation Oncology*Biology*Physics. 90: S34. DOI: 10.1016/J.Ijrobp.2014.05.145  0.706
2014 Brennan C, Verhaak R, McKenna A, Campos B, Noushmehr H, Salama S, Zheng S, Chakravarty D, Sanborn J, Berman S, Beroukhim R, Bernard B, Wu C, Genovese G, Shmulevich I, ... ... Meyerson M, et al. The Somatic Genomic Landscape of Glioblastoma Cell. 157: 753. DOI: 10.1016/J.Cell.2014.04.004  0.695
2014 Freeman S, Bhatt A, Pedamallu C, King S, Duke F, Jung J, Lawton M, Anderson E, Fuhlbrigge RC, Kenna M, Licameli G, Meyerson M, Dedeoglu F. A121: In Search of Infectious Triggers of Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis Syndrome Arthritis & Rheumatism. 66. DOI: 10.1002/Art.38542  0.589
2014 Imielinski M, Hammerman PS, Thomas R, Meyerson M. Somatic Genome Alterations in Human Lung Cancers Lung Cancer: Fourth Edition. 67-89. DOI: 10.1002/9781118468791.ch4  0.315
2013 Kostic AD, Chun E, Meyerson M, Garrett WS. Microbes and inflammation in colorectal cancer. Cancer Immunology Research. 1: 150-7. PMID 24777677 DOI: 10.1158/2326-6066.Cir-13-0101  0.345
2013 Yasuda H, Park E, Yun CH, Sng NJ, Lucena-Araujo AR, Yeo WL, Huberman MS, Cohen DW, Nakayama S, Ishioka K, Yamaguchi N, Hanna M, Oxnard GR, Lathan CS, Moran T, ... ... Meyerson M, et al. Structural, biochemical, and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer. Science Translational Medicine. 5: 216ra177. PMID 24353160 DOI: 10.1126/Scitranslmed.3007205  0.38
2013 Bhatt AS, Marty FM, Meyerson M. Bradyrhizobium enterica in cord colitis syndrome. The New England Journal of Medicine. 369: 1867. PMID 24195568 DOI: 10.1056/Nejmc1311318  0.5
2013 Francis JM, Kiezun A, Ramos AH, Serra S, Pedamallu CS, Qian ZR, Banck MS, Kanwar R, Kulkarni AA, Karpathakis A, Manzo V, Contractor T, Philips J, Nickerson E, Pho N, ... ... Meyerson M, et al. Somatic mutation of CDKN1B in small intestine neuroendocrine tumors. Nature Genetics. 45: 1483-6. PMID 24185511 DOI: 10.1038/Ng.2821  0.582
2013 Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... Meyerson M, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034  0.757
2013 Akbay EA, Koyama S, Carretero J, Altabef A, Tchaicha JH, Christensen CL, Mikse OR, Cherniack AD, Beauchamp EM, Pugh TJ, Wilkerson MD, Fecci PE, Butaney M, Reibel JB, Soucheray M, ... ... Meyerson M, et al. Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors. Cancer Discovery. 3: 1355-63. PMID 24078774 DOI: 10.1158/2159-8290.Cd-13-0310  0.556
2013 Zack TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G, Tabak B, Lawrence MS, Zhsng CZ, Wala J, Mermel CH, Sougnez C, Gabriel SB, Hernandez B, Shen H, Laird PW, ... Meyerson M, et al. Pan-cancer patterns of somatic copy number alteration. Nature Genetics. 45: 1134-40. PMID 24071852 DOI: 10.1038/Ng.2760  0.843
2013 Hanna MC, Go C, Roden C, Jones RT, Pochanard P, Javed AY, Javed A, Mondal C, Palescandolo E, Van Hummelen P, Hatton C, Bass AJ, Chun SM, Na DC, Kim TI, ... Meyerson M, et al. Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency. Plos One. 8: e74950. PMID 24066160 DOI: 10.1371/Journal.Pone.0074950  0.72
2013 Cho J, Chen L, Sangji N, Okabe T, Yonesaka K, Francis JM, Flavin RJ, Johnson W, Kwon J, Yu S, Greulich H, Johnson BE, Eck MJ, Jänne PA, Wong KK, ... Meyerson M, et al. Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization. Cancer Research. 73: 6770-9. PMID 24063894 DOI: 10.1158/0008-5472.Can-13-1145  0.386
2013 Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M. Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Research. 73: 6289-98. PMID 23980093 DOI: 10.1158/0008-5472.Can-13-1616  0.724
2013 Kostic AD, Chun E, Robertson L, Glickman JN, Gallini CA, Michaud M, Clancy TE, Chung DC, Lochhead P, Hold GL, El-Omar EM, Brenner D, Fuchs CS, Meyerson M, Garrett WS. Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment. Cell Host & Microbe. 14: 207-15. PMID 23954159 DOI: 10.1016/J.Chom.2013.07.007  0.355
2013 Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, ... Meyerson M, et al. Signatures of mutational processes in human cancer. Nature. 500: 415-21. PMID 23945592 DOI: 10.1038/Nature12477  0.476
2013 Bhatt AS, Freeman SS, Herrera AF, Pedamallu CS, Gevers D, Duke F, Jung J, Michaud M, Walker BJ, Young S, Earl AM, Kostic AD, Ojesina AI, Hasserjian R, Ballen KK, ... ... Meyerson M, et al. Sequence-based discovery of Bradyrhizobium enterica in cord colitis syndrome. The New England Journal of Medicine. 369: 517-28. PMID 23924002 DOI: 10.1056/Nejmoa1211115  0.556
2013 Li BE, Gan T, Meyerson M, Rabbitts TH, Ernst P. Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells. Blood. 122: 2039-46. PMID 23908472 DOI: 10.1182/Blood-2013-03-486647  0.33
2013 Liao RG, Jung J, Tchaicha J, Wilkerson MD, Sivachenko A, Beauchamp EM, Liu Q, Pugh TJ, Pedamallu CS, Hayes DN, Gray NS, Getz G, Wong KK, Haddad RI, Meyerson M, et al. Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. Cancer Research. 73: 5195-205. PMID 23786770 DOI: 10.1158/0008-5472.Can-12-3950  0.615
2013 Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, Carter SL, Stewart C, Mermel CH, Roberts SA, Kiezun A, Hammerman PS, McKenna A, Drier Y, Zou L, ... Meyerson M, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 499: 214-8. PMID 23770567 DOI: 10.1038/Nature12213  0.838
2013 Watanabe H, Meyerson M. Hopping between differentiation states in lung adenocarcinoma. Cancer Cell. 23: 707-9. PMID 23763994 DOI: 10.1016/J.Ccr.2013.05.013  0.349
2013 Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM. A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science (New York, N.Y.). 340: 1100-6. PMID 23723238 DOI: 10.1126/Science.1232044  0.375
2013 Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Ghandi M, Van Allen E, Kryukov GV, Sboner A, Theurillat JP, Soong TD, ... Meyerson M, et al. Punctuated evolution of prostate cancer genomes. Cell. 153: 666-77. PMID 23622249 DOI: 10.1016/J.Cell.2013.03.021  0.728
2013 Snyder EL, Watanabe H, Magendantz M, Hoersch S, Chen TA, Wang DG, Crowley D, Whittaker CA, Meyerson M, Kimura S, Jacks T. Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. Molecular Cell. 50: 185-99. PMID 23523371 DOI: 10.1016/J.Molcel.2013.02.018  0.53
2013 Cibulskis K, Lawrence MS, Carter SL, Sivachenko A, Jaffe D, Sougnez C, Gabriel S, Meyerson M, Lander ES, Getz G. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nature Biotechnology. 31: 213-9. PMID 23396013 DOI: 10.1038/Nbt.2514  0.461
2013 Pugh TJ, Morozova O, Attiyeh EF, Asgharzadeh S, Wei JS, Auclair D, Carter SL, Cibulskis K, Hanna M, Kiezun A, Kim J, Lawrence MS, Lichenstein L, McKenna A, Pedamallu CS, ... ... Meyerson M, et al. The genetic landscape of high-risk neuroblastoma. Nature Genetics. 45: 279-84. PMID 23334666 DOI: 10.1038/Ng.2529  0.675
2013 Watanabe H, Francis JM, Woo MS, Etemad B, Lin W, Fries DF, Peng S, Snyder EL, Tata PR, Izzo F, Schinzel AC, Cho J, Hammerman PS, Verhaak RG, Hahn WC, ... ... Meyerson M, et al. Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target. Genes & Development. 27: 197-210. PMID 23322301 DOI: 10.1101/Gad.203208.112  0.595
2013 Chmielecki J, Crago AM, Rosenberg M, O'Connor R, Walker SR, Ambrogio L, Auclair D, McKenna A, Heinrich MC, Frank DA, Meyerson M. Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors. Nature Genetics. 45: 131-2. PMID 23313954 DOI: 10.1038/Ng.2522  0.332
2013 Verhaak RG, Tamayo P, Yang JY, Hubbard D, Zhang H, Creighton CJ, Fereday S, Lawrence M, Carter SL, Mermel CH, Kostic AD, Etemadmoghadam D, Saksena G, Cibulskis K, Duraisamy S, ... Meyerson M, et al. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. The Journal of Clinical Investigation. 123: 517-25. PMID 23257362 DOI: 10.1172/Jci65833  0.385
2013 Drier Y, Lawrence MS, Carter SL, Stewart C, Gabriel SB, Lander ES, Meyerson M, Beroukhim R, Getz G. Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. Genome Research. 23: 228-35. PMID 23124520 DOI: 10.1101/Gr.141382.112  0.71
2013 Ojesina AI, Pedamallu CS, Kostic A, Jung J, Auclair D, Lohr J, Carpten J, Getz G, Keats JJ, Meyerson M. High Throughput Sequencing-Based Pathogen Discovery In Multiple Myeloma Blood. 122: 5322-5322. DOI: 10.1182/Blood.V122.21.5322.5322  0.374
2013 Wan Y, Brooks AN, Wang L, Sougnez C, Zhang W, Wong J, Landau D, Kotliar D, Deluca D, Brown JR, Reed R, Getz G, Meyerson M, Wu CJ. SF3B1 Mutation Alters The Selection Of 3' RNA Splice Sites In Chronic Lymphocytic Leukemia Blood. 122: 117-117. DOI: 10.1182/Blood.V122.21.117.117  0.41
2013 Meyerson M. Abstract IA2: Somatic alterations in human cancer genomes Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia2  0.494
2013 Solimini N, Pavlova NN, Mermel C, Xu Q, Burrows AE, Luo J, li M, Beroukhim R, Meyerson M, Elledge SJ. Abstract SY25-03: Haploinsufficiency in cancer: When half simply isn't good enough. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy25-03  0.629
2013 Liao RG, Sivachenko A, Getz G, Dutt A, Hammerman PS, Meyerson M. Abstract 963: Characterizing acquired resistance mechanisms to targeted therapy in FGFR1-amplified lung squamous cell carcinoma. Cancer Research. 73: 963-963. DOI: 10.1158/1538-7445.Am2013-963  0.677
2013 Stojanov P, Carter SL, Rosshandler II, Sivachenko A, Guadarrama AS, Vazquez K, Cordoba SR, Cibulskis K, Sougnez C, Voet D, Saksena G, Lichtenstein L, Zou L, Frazer S, Stewart C, ... ... Meyerson M, et al. Abstract 5135: Analysis of formalin-fixed paraffin-embedded (FFPE) samples. Cancer Research. 73: 5135-5135. DOI: 10.1158/1538-7445.Am2013-5135  0.665
2013 Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Allen EV, Kryukov GV, Theurillat J, Soong TD, Nickerson E, Auclair D, ... Meyerson M, et al. Abstract 4601: Punctuated evolution of prostate cancer genomes. Cancer Research. 73: 4601-4601. DOI: 10.1158/1538-7445.Am2013-4601  0.444
2013 Carter SL, Landau D, Stojanov P, McKenna A, Cibulskis K, Lawrence MS, Lohr J, Stevenson K, Neuberg D, Meyerson M, Wu CJ, Getz G. Abstract 4600: Analysis of clonal evolution in cancer using whole exome sequence data reveals that subclonal driver mutations predict poor prognosis in chronic lymphocytic leukemia. Cancer Research. 73: 4600-4600. DOI: 10.1158/1538-7445.Am2013-4600  0.471
2013 Bhatt AS, Pedamallu CS, Duke F, Jung J, Freeman SS, Cherniak A, Park R, Kim J, Kwiatkowski D, Rosenberg J, Meyerson M. Abstract 4149: Transcriptomic and pathogen analysis in bladder cancer primary tumor and metastasis pairs. Cancer Research. 73: 4149-4149. DOI: 10.1158/1538-7445.Am2013-4149  0.686
2013 Sasaki MM, Skol AD, Pugh TJ, Meyerson M, Onel K. Abstract 4018: Whole exome sequencing analysis of familial Medulloblastoma. Cancer Research. 73: 4018-4018. DOI: 10.1158/1538-7445.Am2013-4018  0.629
2013 Prandi D, Baca SC, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Allen EV, Kryukov GV, Theurillat J, Soong TD, Nickerson E, Auclair D, ... Meyerson M, et al. Abstract 4017: Dissecting the clonal hierarchy of cancer-driving genomic lesions. Cancer Research. 73: 4017-4017. DOI: 10.1158/1538-7445.Am2013-4017  0.49
2013 Pugh TJ, Yu W, Yang J, Ambrogio L, Carter SL, Kiezun A, McKenna A, Giannikopoulos P, Getz G, Messinger Y, Meyerson M, Hill DA. Abstract 3806: Progressive biallelic loss of TP53 is associated with progression of pleuropulmonary blastoma initiated by germline loss and somatic mutation of DICER1. Cancer Research. 73: 3806-3806. DOI: 10.1158/1538-7445.Am2013-3806  0.618
2013 Wood AC, Pugh TJ, Morozova O, Koster J, Molenaar JJ, Pineros V, Bosse KR, Perin JC, Diskin S, Diamond MA, Marra M, Meyerson M, Versteeg R, Maris JM. Abstract 3804: Rare DNA variants are enriched at the BARD1 locus and likely influence neuroblastoma susceptibility. Cancer Research. 73: 3804-3804. DOI: 10.1158/1538-7445.Am2013-3804  0.678
2013 Brooks AN, Wan Y, Choi P, Jing R, DeLuca DS, Sougnez C, Chmielecki J, Imielinski M, Getz G, Wu CJ, Meyerson M. Abstract 3150: Characterizing the effects of somatic mutations in splice factors on the transcriptome. Cancer Research. 73: 3150-3150. DOI: 10.1158/1538-7445.Am2013-3150  0.331
2013 Watanabe H, Francis JM, Woo MS, Etemad B, Lin W, Fries DF, Peng S, Snyder EL, Tata PR, Schinzel AC, Cho J, Hammerman PS, Verhaak RG, Hahn WC, Rajagopal J, ... Meyerson M, et al. Abstract 3127: Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target. Cancer Research. 73: 3127-3127. DOI: 10.1158/1538-7445.Am2013-3127  0.661
2013 Kim K, Zhang Y, Choi K, Do I, Meyerson M, Cho J. Abstract 3021: Mechanistic insight into MIG6 phosphorylation-mediated inhibitory effect on active EGFR. Cancer Research. 73: 3021-3021. DOI: 10.1158/1538-7445.Am2013-3021  0.365
2013 Jung J, Pedamallu CS, Kostic AD, Freeman S, Ojesina AI, Berger A, Bhatt A, Duke F, Getz G, Meyerson M. Abstract 1501: Pan-cancer PathSeq analysis on TCGA data for pathogen discovery. Cancer Research. 73: 1501-1501. DOI: 10.1158/1538-7445.Am2013-1501  0.439
2013 Chmielecki J, Rosenberg M, Imielinski M, Hernandez B, Lawrence M, Sivachenko A, Cibulskis K, Voet D, Sougnez C, Gabriel S, Getz G, Meyerson M. Abstract 1112: Whole exome and whole genome sequence analysis of lung adenocarcinoma. Cancer Research. 73: 1112-1112. DOI: 10.1158/1538-7445.Am2013-1112  0.516
2013 Berger A, Imielinski M, Duke F, Wala J, Kaplan N, Shi G, Andres D, Meyerson M. Abstract C140: RIT1 mutations define a new genetic subset of lung adenocarcinoma. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C140  0.743
2013 Greulich HE, Imielinski M, Kaplan B, Araujo L, Amann J, Horn L, Villalona M, Meyerson M, Carbone D. Abstract C139: Oncogenic ARAF mutation in a metastatic lung adenocarcinoma from a patient exhibiting sustained sorafenib response. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C139  0.491
2013 Kim H, Zheng S, Amini SS, Virk S, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Sloan AE, Cohen ML, Meir EGV, Scarpace L, Laird PW, Weinstein JN, Lander ES, ... Meyerson M, et al. Abstract B130: The intratumoral heterogeneity of glioblastoma suggests a pivotal role for clonal evolution. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B130  0.49
2013 Imielinski M, Du C, Meyerson M. Abstract A22: Identifying somatic mutation hotspots across protein family alignments. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A22  0.386
2013 Adachi K, Sasaki H, Nagahisa S, Yoshida K, Hattori N, Nishiyama Y, Kawase T, Hasegawa M, Abe M, Hirose Y, Alentorn A, Marie Y, Poggioli S, Alshehhi H, Boisselier B, ... ... Meyerson M, et al. OMICS AND PROGNSTIC MARKERS Neuro-Oncology. 15: iii136-iii155. DOI: 10.1093/Neuonc/Not183  0.406
2013 Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SAJR, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale A, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, ... ... Meyerson M, et al. Corrigendum: Signatures of mutational processes in human cancer Nature. 502: 258-258. DOI: 10.1038/Nature12666  0.344
2013 Creighton CJ, Morgan M, Gunaratne PH, Wheeler DA, Gibbs RA, Robertson G, Chu A, Beroukhim R, Cibulskis K, Signoretti S, Vandin F, Wu HT, Raphael BJ, Verhaak RGW, Tamboli P, ... ... Meyerson M, et al. Comprehensivemolecular characterization of clear cell renal cell carcinoma Nature. 499: 43-49. DOI: 10.1038/Nature12222  0.597
2013 Bhatt AS, Freeman S, Herrera A, Pedamallu CS, Gevers D, Jung J, Duke F, Young S, Earl A, Kostic A, Ojesina A, Soriano G, Walker BJ, Soiffer RJ, Antin JH, ... ... Meyerson M, et al. Sequence-Based Discovery of Novel Bacteria, Bradyrhizobium Enterica, in Cord Colitis Syndrome Biology of Blood and Marrow Transplantation. 19: S281-S282. DOI: 10.1016/J.Bbmt.2012.11.400  0.538
2012 Liao RG, Watanabe H, Meyerson M, Hammerman PS. Targeted therapy for squamous cell lung cancer. Lung Cancer Management. 1: 293-300. PMID 23956794 DOI: 10.2217/Lmt.12.40  0.372
2012 Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, ... Meyerson M, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell. 150: 1107-20. PMID 22980975 DOI: 10.1016/J.Cell.2012.08.029  0.786
2012 Hammerman PS, Voet D, Lawrence MS, Jing R, Cibulskis K, Sivachenko A, Stojanov P, McKenna A, Lander ES, Gabriel S, Getz G, Imielinski M, Helman E, Hernandez B, Pho NH, Meyerson M, et al. Comprehensive genomic characterization of squamous cell lung cancers Nature. 489: 519-525. PMID 22960745 DOI: 10.1038/Nature11404  0.844
2012 Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, ... Meyerson M, et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nature Genetics. 44: 1104-10. PMID 22941188 DOI: 10.1038/Ng.2396  0.507
2012 Greulich H, Kaplan B, Mertins P, Chen TH, Tanaka KE, Yun CH, Zhang X, Lee SH, Cho J, Ambrogio L, Liao R, Imielinski M, Banerji S, Berger AH, Lawrence MS, ... ... Meyerson M, et al. Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. Proceedings of the National Academy of Sciences of the United States of America. 109: 14476-81. PMID 22908275 DOI: 10.1073/Pnas.1203201109  0.752
2012 Jones DT, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz HJ, Ryzhova M, Bender S, Sturm D, ... Meyerson M, et al. Dissecting the genomic complexity underlying medulloblastoma. Nature. 488: 100-5. PMID 22832583 DOI: 10.1038/Nature11284  0.607
2012 Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, ... ... Meyerson M, et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 488: 49-56. PMID 22832581 DOI: 10.1038/Nature11327  0.688
2012 Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, Carneiro MO, Carter SL, Cibulskis K, Erlich RL, Greulich H, Lawrence MS, Lennon NJ, McKenna A, Meldrim J, ... ... Meyerson M, et al. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature. 488: 106-10. PMID 22820256 DOI: 10.1038/Nature11329  0.601
2012 Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, ... ... Meyerson M, et al. A landscape of driver mutations in melanoma. Cell. 150: 251-63. PMID 22817889 DOI: 10.1016/J.Cell.2012.06.024  0.713
2012 Shimamura T, Perera SA, Foley KP, Sang J, Rodig SJ, Inoue T, Chen L, Li D, Carretero J, Li YC, Sinha P, Carey CD, Borgman CL, Jimenez JP, Meyerson M, et al. Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4973-85. PMID 22806877 DOI: 10.1158/1078-0432.Ccr-11-2967  0.364
2012 Dulak AM, Schumacher SE, van Lieshout J, Imamura Y, Fox C, Shim B, Ramos AH, Saksena G, Baca SC, Baselga J, Tabernero J, Barretina J, Enzinger PC, Corso G, Roviello F, ... Meyerson M, et al. Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Research. 72: 4383-93. PMID 22751462 DOI: 10.1158/0008-5472.Can-11-3893  0.787
2012 Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Cortes ML, Fernandez-Lopez JC, Peng S, Ardlie KG, Auclair D, ... Meyerson M, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 486: 405-9. PMID 22722202 DOI: 10.1038/Nature11154  0.709
2012 Solimini NL, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ. Recurrent hemizygous deletions in cancers may optimize proliferative potential. Science (New York, N.Y.). 337: 104-9. PMID 22628553 DOI: 10.1126/Science.1219580  0.676
2012 Berger MF, Hodis E, Heffernan TP, Deribe YL, Lawrence MS, Protopopov A, Ivanova E, Watson IR, Nickerson E, Ghosh P, Zhang H, Zeid R, Ren X, Cibulskis K, Sivachenko AY, ... Meyerson M, et al. Melanoma genome sequencing reveals frequent PREX2 mutations. Nature. 485: 502-6. PMID 22622578 DOI: 10.1038/Nature11071  0.783
2012 Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, ... Meyerson M, et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nature Genetics. 44: 685-9. PMID 22610119 DOI: 10.1038/Ng.2279  0.728
2012 Wagle N, Berger MF, Davis MJ, Blumenstiel B, Defelice M, Pochanard P, Ducar M, Van Hummelen P, Macconaill LE, Hahn WC, Meyerson M, Gabriel SB, Garraway LA. High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing. Cancer Discovery. 2: 82-93. PMID 22585170 DOI: 10.1158/2159-8290.CD-11-0184  0.546
2012 Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, et al. Absolute quantification of somatic DNA alterations in human cancer. Nature Biotechnology. 30: 413-21. PMID 22544022 DOI: 10.1038/Nbt.2203  0.842
2012 Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, ... Meyerson M, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 483: 603-7. PMID 22460905 DOI: 10.1038/Nature11003  0.783
2012 Lin L, Bass AJ, Lockwood WW, Wang Z, Silvers AL, Thomas DG, Chang AC, Lin J, Orringer MB, Li W, Glover TW, Giordano TJ, Lam WL, Meyerson M, Beer DG. Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 109: 4251-6. PMID 22375031 DOI: 10.1073/Pnas.1011989109  0.658
2012 Basseres DS, D'Alò F, Yeap BY, Löwenberg EC, Gonzalez DA, Yasuda H, Dayaram T, Kocher ON, Godleski JJ, Richards WG, Meyerson M, Kobayashi S, Tenen DG, Halmos B, Costa DB. Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing. Lung Cancer (Amsterdam, Netherlands). 77: 31-7. PMID 22341411 DOI: 10.1016/J.Lungcan.2012.01.011  0.385
2012 Jänne PA, Meyerson M. ROS1 rearrangements in lung cancer: a new genomic subset of lung adenocarcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 878-9. PMID 22215755 DOI: 10.1200/Jco.2011.39.4197  0.45
2012 Kostic AD, Gevers D, Pedamallu CS, Michaud M, Duke F, Earl AM, Ojesina AI, Jung J, Bass AJ, Tabernero J, Baselga J, Liu C, Shivdasani RA, Ogino S, Birren BW, ... Meyerson M, et al. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Research. 22: 292-8. PMID 22009990 DOI: 10.1101/Gr.126573.111  0.656
2012 Govindan R, Hammerman PS, Hayes DN, Wilkerson MD, Baylin S, Meyerson M. Comprehensive genomic characterization of squamous cell carcinoma of the lung. Journal of Clinical Oncology. 30: 7006-7006. DOI: 10.1200/Jco.2012.30.15_Suppl.7006  0.409
2012 Jäger N, Jones DT, Kool M, Zichner T, Hutter B, Sultan M, Cho Y, Pugh TJ, Hovestadt V, Stütz AM, Rausch T, Warnatz H, Brors B, Northcott PA, Taylor MD, ... Meyerson M, et al. ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P43  0.528
2012 Erlich RL, Palescandolo E, Jones RT, Sunkavalli A, Raza A, Ducar M, Hatton C, Go C, Roden C, Hanna M, Mills A, Adusumilli R, Kumar P, Brastianos PK, Meyerson ML, et al. Massively parallel sequencing of formalin-fixed paraffin-embedded tissues Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P40  0.396
2012 Bhatt AS, Freeman SS, Herrera AF, Pedamallu CS, Gevers D, Duke F, Jung J, Walker BJ, Young S, Earl A, Kostic A, Ojesina AI, Soriano G, Antin JH, Soiffer RJ, ... ... Meyerson M, et al. Next-Generation Sequencing for the Identification of Transplantation-Associated Pathogens Blood. 120: LBA-4-LBA-4. DOI: 10.1182/Blood.V120.21.Lba-4.Lba-4  0.6
2012 Landau D, Carter S, Stojanov P, Stevenson KE, Mckenna A, Lawrence M, Sougnez C, Sivachenko A, Wang L, Zhang W, Sachet S, Vartanov AR, Fernandes SM, Cibulskis K, Tesar B, ... ... Meyerson M, et al. The Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia Blood. 120: 5-5. DOI: 10.1182/Blood.V120.21.5.5  0.415
2012 Solimini NL, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ, Pavlova NN, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN. Abstract IA8: Genetic approaches to cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Csb12-Ia8  0.685
2012 Helman E, Lawrence M, Stewart C, Getz G, Meyerson M. Abstract 5060: Identification of somatic retrotransposon insertions across cancer types using RetroSeq Cancer Research. 72: 5060-5060. DOI: 10.1158/1538-7445.Am2012-5060  0.492
2012 Hodis E, Watson I, Theurillat J, Zou L, Place C, Nickerson E, Auclair D, Cibulskis K, Sivachenko A, Kryukov G, Stransky N, Ramos AH, Voet D, Lawrence MS, Stojanov P, ... Meyerson M, et al. Abstract 5056: A glimpse into the somatic mutation landscape of melanoma through exome sequencing of 121 tumor-normal pairs Cancer Research. 72: 5056-5056. DOI: 10.1158/1538-7445.Am2012-5056  0.641
2012 Pugh TJ, Cho Y, Archer T, Weeraratne D, Jones DTW, Jaeger N, Auclair D, Cibulskis K, Lawrence MS, Ramos AH, Shefler E, Sivachenko A, Tamayo P, Mesirov JP, Gabriel SB, ... Meyerson M, et al. Abstract 4868: Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations within a wide spectrum of genetic heterogeneity Cancer Research. 72: 4868-4868. DOI: 10.1158/1538-7445.Am2012-4868  0.617
2012 Basseres DS, D'Alò F, Yeap BY, Gonzalez DA, Yasuda H, Meyerson M, Kobayashi S, Tenen DG, Halmos B, Costa DB. Abstract 4036: Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing Cancer Research. 72: 4036-4036. DOI: 10.1158/1538-7445.Am2012-4036  0.456
2012 Hatton C, Niu L, Davis M, Mondal C, Luongo L, Go C, Jones RT, Roden C, Palescandolo E, Hummelen PV, Garraway LA, Meyerson M, Hahn W, MacConaill LE. Abstract 3965: An algorithm to detect somatic mutations in cancer specimens using mass spectrometric genotyping Cancer Research. 72: 3965-3965. DOI: 10.1158/1538-7445.Am2012-3965  0.561
2012 Liao R, Hammerman P, Sivachenko A, Greulich H, Getz G, Liu Q, Gray N, Meyerson M. Abstract 2: FGFR3 as a therapeutic target in squamous cell lung carcinoma Cancer Research. 72: 2-2. DOI: 10.1158/1538-7445.Am2012-2  0.48
2012 Imielinski M, Hernandez B, Lawrence M, Hodis E, Kryukov G, Stojanov P, Sivachenko A, Cibulskis K, Sougnez C, Auclair D, Ardlie K, Banerji S, Hammerman P, Thomas RK, Gabriel S, ... Meyerson M, et al. Abstract 1682: Uncovering signals of somatic selection through whole exome and whole genome sequencing of lung adenocarcinoma Cancer Research. 72: 1682-1682. DOI: 10.1158/1538-7445.Am2012-1682  0.496
2012 Weeraratne SD, Archer T, Pugh TJ, Hargreaves D, Yu F, Kautzman A, Jones DTW, Jaeger N, Tamayo P, Mesirov JP, Pfister SM, Lichter P, Crabtree G, Meyerson M, Pomeroy SL, et al. Abstract 1313: Mutually exclusive somatic mutations in WNT pathway medulloblastomas reveal a critical interaction between DDX3X and SMARCA4 Cancer Research. 72: 1313-1313. DOI: 10.1158/1538-7445.Am2012-1313  0.591
2012 Greulich H, Kaplan B, Mertins P, Chen T, Tanaka K, Yun C, Imielinski M, Banerji S, Lawrence MS, Walker S, Winckler W, Getz G, Frank D, Eck M, Jaffe JD, ... Meyerson M, et al. Abstract 1: Oncogenic extracellular domain mutations of ERBB2 in cancer Cancer Research. 72: 1-1. DOI: 10.1158/1538-7445.Am2012-1  0.403
2012 Hernandez B, Hammerman P, Imielinski M, Lawrence M, Stojanov P, Getz G, Meyerson M. Abstract PR1: Integrating expression data improves mutational significance analysis of lung squamous carcinoma Clinical Cancer Research. 18. DOI: 10.1158/1078-0432.12Aacriaslc-Pr1  0.499
2012 Meyerson M. Abstract IA7: Somatic genome alterations in human lung cancers Clinical Cancer Research. 18. DOI: 10.1158/1078-0432.12Aacriaslc-Ia7  0.481
2012 Liao RG, Hammerman P, Sivachencko A, Greulich H, Getz G, Liu Q, Gray N, Meyerson M. Abstract B13: FGFR2 as a therapeutic target in squamous cell lung carcinoma Clinical Cancer Research. 18: B13-B13. DOI: 10.1158/1078-0432.12Aacriaslc-B13  0.462
2012 Banerji S, Cibulskis K, Rangel-Escareño C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Cortes ML, Fernandez-Lopez JC, Peng S, Ardlie KG, Auclair D, ... Meyerson M, et al. Abstract PL07-01: Molecular profiling of breast cancer in Mexico: Identification of novel therapeutic targets through whole genome sequencing analysis. Cancer Epidemiology, Biomarkers & Prevention. 21. DOI: 10.1158/1055-9965.Disp12-Pl07-01  0.697
2012 Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, J.Wilson C, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, ... ... Meyerson M, et al. Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity Nature. DOI: 10.1038/nature11735  0.496
2012 Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YSN, Carlsen R, ... Meyerson M, et al. Comprehensive molecular portraits of human breast tumours Nature. 490: 61-70. DOI: 10.1038/Nature11412  0.821
2012 Barbieri C, Baca S, Demichelis F, Lawrence M, Blattner M, Theurillat J, Boysen G, Stojanov P, Van Allen E, Stransky N, Nickerson E, Park K, Kitabayashi N, MacDonald T, Vuong T, ... ... Meyerson M, et al. 1314 RECURRENT MUTATIONS IN SPOP DEFINE A DISTINCT MOLECULAR CLASS OF PROSTATE CANCER Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.1661  0.378
2012 Abazeed M, Hammerman P, Creighton C, Adams D, Giacomelli A, Meyerson M. NRF2 Pathway Activation Regulates Radiation Resistance in Lung Squamous Cell Carcinoma International Journal of Radiation Oncology*Biology*Physics. 84: S179-S180. DOI: 10.1016/J.Ijrobp.2012.07.465  0.614
2012 Abazeed M, Adams D, Giacomelli A, Pashtan I, Hammerman P, Meyerson M. Development of a High Throughput Platform for Measuring Radiation Response International Journal of Radiation Oncology*Biology*Physics. 84: S701. DOI: 10.1016/J.Ijrobp.2012.07.1874  0.568
2011 Wagle N, Berger MF, Davis MJ, Blumenstiel B, DeFelice M, Hahn WC, Meyerson M, Gabriel SB, MacConaill LE, Garraway LA. Tumor genomic profiling of FFPE samples by massively parallel sequencing. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 10502. PMID 28022364 DOI: 10.1200/Jco.2011.29.15_Suppl.10502  0.529
2011 Cheung HW, Du J, Boehm JS, He F, Weir BA, Wang X, Butaney M, Sequist LV, Luo B, Engelman JA, Root DE, Meyerson M, Golub TR, Jänne PA, Hahn WC. Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers. Cancer Discovery. 1: 608-25. PMID 22586683 DOI: 10.1158/2159-8290.Cd-11-0046  0.562
2011 Hammerman PS, Sos ML, Ramos AH, Xu C, Dutt A, Zhou W, Brace LE, Woods BA, Lin W, Zhang J, Deng X, Lim SM, Heynck S, Peifer M, Simard JR, ... Meyerson M, et al. Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discovery. 1: 78-89. PMID 22328973 DOI: 10.1158/2159-8274.Cd-11-0005  0.844
2011 Wang L, Lawrence MS, Wan Y, Stojanov P, Sougnez C, Stevenson K, Werner L, Sivachenko A, DeLuca DS, Zhang L, Zhang W, Vartanov AR, Fernandes SM, Goldstein NR, Folco EG, ... ... Meyerson M, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. The New England Journal of Medicine. 365: 2497-506. PMID 22150006 DOI: 10.1056/Nejmoa1109016  0.421
2011 Fudenberg G, Getz G, Meyerson M, Mirny LA. High order chromatin architecture shapes the landscape of chromosomal alterations in cancer. Nature Biotechnology. 29: 1109-13. PMID 22101486 DOI: 10.1038/Nbt.2049  0.424
2011 Cho J, Pastorino S, Zeng Q, Xu X, Johnson W, Vandenberg S, Verhaak R, Cherniack AD, Watanabe H, Dutt A, Kwon J, Chao YS, Onofrio RC, Chiang D, Yuza Y, ... ... Meyerson M, et al. Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies. Cancer Research. 71: 7587-96. PMID 22001862 DOI: 10.1158/0008-5472.Can-11-0821  0.657
2011 MacConaill LE, Van Hummelen P, Meyerson M, Hahn WC. Clinical implementation of comprehensive strategies to characterize cancer genomes: opportunities and challenges. Cancer Discovery. 1: 297-311. PMID 21935500 DOI: 10.1158/2159-8290.Cd-11-0110  0.601
2011 Bass AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y, Cibulskis K, Sougnez C, Voet D, Saksena G, Sivachenko A, Jing R, Parkin M, Pugh T, Verhaak RG, Stransky N, ... Meyerson M, et al. Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nature Genetics. 43: 964-8. PMID 21892161 DOI: 10.1038/Ng.936  0.789
2011 Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, ... Meyerson M, et al. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nature Genetics. 43: 869-74. PMID 21804546 DOI: 10.1038/Ng.890  0.752
2011 Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence MS, Sougnez C, McKenna A, Shefler E, Ramos AH, Stojanov P, Carter SL, Voet D, ... ... Meyerson M, et al. The mutational landscape of head and neck squamous cell carcinoma. Science (New York, N.Y.). 333: 1157-60. PMID 21798893 DOI: 10.1126/Science.1208130  0.727
2011 Lin W, Cao J, Liu J, Beshiri ML, Fujiwara Y, Francis J, Cherniack AD, Geisen C, Blair LP, Zou MR, Shen X, Kawamori D, Liu Z, Grisanzio C, Watanabe H, ... ... Meyerson M, et al. Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1. Proceedings of the National Academy of Sciences of the United States of America. 108: 13379-86. PMID 21788502 DOI: 10.1073/Pnas.1110104108  0.318
2011 Dooley AL, Winslow MM, Chiang DY, Banerji S, Stransky N, Dayton TL, Snyder EL, Senna S, Whittaker CA, Bronson RT, Crowley D, Barretina J, Garraway L, Meyerson M, Jacks T. Nuclear factor I/B is an oncogene in small cell lung cancer. Genes & Development. 25: 1470-5. PMID 21764851 DOI: 10.1101/Gad.2046711  0.552
2011 Cheung HW, Cowley GS, Weir BA, Boehm JS, Rusin S, Scott JA, East A, Ali LD, Lizotte PH, Wong TC, Jiang G, Hsiao J, Mermel CH, Getz G, Barretina J, ... Meyerson M, et al. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 12372-7. PMID 21746896 DOI: 10.1073/Pnas.1109363108  0.62
2011 Takahashi A, Tsutsumi R, Kikuchi I, Obuse C, Saito Y, Seidi A, Karisch R, Fernandez M, Cho T, Ohnishi N, Rozenblatt-Rosen O, Meyerson M, Neel BG, Hatakeyama M. SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver. Molecular Cell. 43: 45-56. PMID 21726809 DOI: 10.1016/J.Molcel.2011.05.014  0.318
2011 Dutt A, Ramos AH, Hammerman PS, Mermel C, Cho J, Sharifnia T, Chande A, Tanaka KE, Stransky N, Greulich H, Gray NS, Meyerson M. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. Plos One. 6: e20351. PMID 21666749 DOI: 10.1371/Journal.Pone.0020351  0.63
2011 Kostic AD, Ojesina AI, Pedamallu CS, Jung J, Verhaak RG, Getz G, Meyerson M. PathSeq: software to identify or discover microbes by deep sequencing of human tissue. Nature Biotechnology. 29: 393-6. PMID 21552235 DOI: 10.1038/Nbt.1868  0.311
2011 Mermel CH, Schumacher SE, Hill B, Meyerson ML, Beroukhim R, Getz G. GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biology. 12: R41. PMID 21527027 DOI: 10.1186/Gb-2011-12-4-R41  0.632
2011 Winslow MM, Dayton TL, Verhaak RG, Kim-Kiselak C, Snyder EL, Feldser DM, Hubbard DD, DuPage MJ, Whittaker CA, Hoersch S, Yoon S, Crowley D, Bronson RT, Chiang DY, Meyerson M, et al. Suppression of lung adenocarcinoma progression by Nkx2-1. Nature. 473: 101-4. PMID 21471965 DOI: 10.1038/Nature09881  0.58
2011 Wilbertz T, Wagner P, Petersen K, Stiedl AC, Scheble VJ, Maier S, Reischl M, Mikut R, Altorki NK, Moch H, Fend F, Staebler A, Bass AJ, Meyerson M, Rubin MA, et al. SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 944-53. PMID 21460799 DOI: 10.1038/Modpathol.2011.49  0.639
2011 Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, ... Meyerson M, et al. Initial genome sequencing and analysis of multiple myeloma. Nature. 471: 467-72. PMID 21430775 DOI: 10.1038/Nature09837  0.818
2011 Chin L, Hahn WC, Getz G, Meyerson M. Making sense of cancer genomic data. Genes & Development. 25: 534-55. PMID 21406553 DOI: 10.1101/Gad.2017311  0.589
2011 Wagle N, Emery C, Berger MF, Davis MJ, Sawyer A, Pochanard P, Kehoe SM, Johannessen CM, Macconaill LE, Hahn WC, Meyerson M, Garraway LA. Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3085-96. PMID 21383288 DOI: 10.1200/Jco.2010.33.2312  0.558
2011 Tamayo P, Cho YJ, Tsherniak A, Greulich H, Ambrogio L, Schouten-van Meeteren N, Zhou T, Buxton A, Kool M, Meyerson M, Pomeroy SL, Mesirov JP. Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1415-23. PMID 21357789 DOI: 10.1200/Jco.2010.28.1675  0.311
2011 Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, Sougnez C, Onofrio R, Carter SL, Park K, Habegger L, Ambrogio L, ... Meyerson M, et al. The genomic complexity of primary human prostate cancer. Nature. 470: 214-20. PMID 21307934 DOI: 10.1038/Nature09744  0.76
2011 Francis J, Lin W, Rozenblatt-Rosen O, Meyerson M. The menin tumor suppressor protein is phosphorylated in response to DNA damage Plos One. 6. PMID 21264250 DOI: 10.1371/Journal.Pone.0016119  0.346
2011 Meyerson M, Pellman D. Cancer genomes evolve by pulverizing single chromosomes. Cell. 144: 9-10. PMID 21215363 DOI: 10.1016/J.Cell.2010.12.025  0.394
2011 Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, Berhoukim R, Amani V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Delattre O, ... ... Meyerson M, et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1424-30. PMID 21098324 DOI: 10.1200/Jco.2010.28.5148  0.356
2011 Wan Y, Lawrence MS, Wang L, Stojanov P, Sougnez C, Stevenson K, Werner L, Zhang W, Folco EG, Tesar B, Sievers QL, Gabriel S, Hacohen N, Reed R, Meyerson M, et al. Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1 Blood. 118: 463-463. DOI: 10.1182/Blood.V118.21.463.463  0.435
2011 Ojesina AI, Kostic A, Pedamallu CS, Jung J, Duke F, Getz G, Meyerson M. Abstract 949: PathSeq: A comprehensive computational tool for pathogen discovery by deep sequencing of human cancer tissues Cancer Research. 71: 949-949. DOI: 10.1158/1538-7445.Am2011-949  0.397
2011 Lin W, Francis J, Watanabe H, Yan Q, Kaelin WG, Meyerson M. Abstract 62: Inhibition ofMen1-deficient tumor growth by inactivation of the Rbp2 histone demethylase Cancer Research. 71: 62-62. DOI: 10.1158/1538-7445.Am2011-62  0.303
2011 Barretina J, Stransky N, Caponigro G, Kim S, Margolin A, Venkhatesan K, Kryukov G, Berger M, Monahan J, Morais P, Meltzer J, Mahan S, Sonkin D, Raman P, Jones M, ... Meyerson M, et al. Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity Cancer Research. 71: 5455-5455. DOI: 10.1158/1538-7445.Am2011-5455  0.639
2011 Cho Y, Tamayo P, Tsherniak A, Meyerson M, Mesirov JP, Pomeroy SL. Abstract 4760: Molecular classification and risk-stratification in medulloblastoma using an integrative genomic approach Cancer Research. 71: 4760-4760. DOI: 10.1158/1538-7445.Am2011-4760  0.377
2011 Wagle N, Emery C, Berger MF, Davis MJ, Sawyer A, Pochanard P, Kehoe SM, Johannessen CM, Macconaill LE, Hahn WC, Meyerson M, Garraway LA. Abstract 3933: Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling Cancer Research. 71: 3933-3933. DOI: 10.1158/1538-7445.Am2011-3933  0.571
2011 Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, Sougnez C, Onofrio R, Carter SL, Park K, Habegger L, Ambrogio L, ... Meyerson M, et al. Abstract 3925: Characterization of complex chromosomal aberrations in prostate cancer from whole genome sequencing Cancer Research. 71: 3925-3925. DOI: 10.1158/1538-7445.Am2011-3925  0.621
2011 Carter SL, Meyerson M, Getz G. Accurate estimation of homologue-specific DNA concentration-ratios in cancer samples allows long-range haplotyping Nature Precedings. DOI: 10.1038/Npre.2011.6494.1  0.306
2011 Fudenberg G, Getz G, Meyerson M, Mirny L. High-order chromatin architecture determines the landscape of chromosomal alterations in cancer Nature Precedings. 6: 1-1. DOI: 10.1038/Npre.2011.6356.1  0.44
2010 Meyerson M, Gabriel S, Getz G. Advances in understanding cancer genomes through second-generation sequencing Nature Reviews Genetics. 11: 685-696. PMID 20847746 DOI: 10.1038/Nrg2841  0.454
2010 Zhu CQ, Ding K, Strumpf D, Weir BA, Meyerson M, Pennell N, Thomas RK, Naoki K, Ladd-Acosta C, Liu N, Pintilie M, Der S, Seymour L, Jurisica I, Shepherd FA, et al. Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4417-24. PMID 20823422 DOI: 10.1200/Jco.2009.26.4325  0.388
2010 Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, ... Meyerson M, et al. Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nature Genetics. 42: 715-21. PMID 20601955 DOI: 10.1038/Ng.619  0.833
2010 Badalian-Very G, Vergilio JA, Degar BA, MacConaill LE, Brandner B, Calicchio ML, Kuo FC, Ligon AH, Stevenson KE, Kehoe SM, Garraway LA, Hahn WC, Meyerson M, Fleming MD, Rollins BJ. Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood. 116: 1919-23. PMID 20519626 DOI: 10.1182/Blood-2010-04-279083  0.573
2010 Scheble VJ, Braun M, Beroukhim R, Mermel CH, Ruiz C, Wilbertz T, Stiedl AC, Petersen K, Reischl M, Kuefer R, Schilling D, Fend F, Kristiansen G, Meyerson M, Rubin MA, et al. ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 23: 1061-7. PMID 20473283 DOI: 10.1038/Modpathol.2010.87  0.673
2010 Zhou W, Hur W, McDermott U, Dutt A, Xian W, Ficarro SB, Zhang J, Sharma SV, Brugge J, Meyerson M, Settleman J, Gray NS. A structure-guided approach to creating covalent FGFR inhibitors. Chemistry & Biology. 17: 285-95. PMID 20338520 DOI: 10.1016/J.Chembiol.2010.02.007  0.728
2010 Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, Moustafa Z, Thomas RK, Greulich H, Schinzel A, Zaghlul S, Batt D, Ettenberg S, Meyerson M, Schoeberl B, et al. An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells. Cancer Cell. 17: 298-310. PMID 20227043 DOI: 10.1016/J.Ccr.2009.12.047  0.58
2010 Berger MF, Levin JZ, Vijayendran K, Sivachenko A, Adiconis X, Maguire J, Johnson LA, Robinson J, Verhaak RG, Sougnez C, Onofrio RC, Ziaugra L, Cibulskis K, Laine E, Barretina J, ... Meyerson M, et al. Integrative analysis of the melanoma transcriptome. Genome Research. 20: 413-27. PMID 20179022 DOI: 10.1101/Gr.103697.109  0.755
2010 Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, ... Meyerson M, et al. The landscape of somatic copy-number alteration across human cancers. Nature. 463: 899-905. PMID 20164920 DOI: 10.1038/Nature08822  0.829
2010 Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, ... Meyerson M, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 17: 98-110. PMID 20129251 DOI: 10.1016/J.Ccr.2009.12.020  0.74
2010 Liang MC, Ma J, Chen L, Kozlowski P, Qin W, Li D, Goto J, Shimamura T, Hayes DN, Meyerson M, Kwiatkowski DJ, Wong KK. TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity. Oncogene. 29: 1588-97. PMID 19966866 DOI: 10.1038/Onc.2009.452  0.433
2010 Dooley AL, Winslow MM, Chiang D, Banerji S, Whittaker C, Bronson R, Crowley D, Meyerson M, Jacks T. Abstract LB-146: Identification of copy number alterations in small cell lung cancer Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-146  0.636
2010 Wagle N, Davis M, Berger MF, Blumenstiel B, Defelice M, Hahn W, Meyerson M, Gabriel SB, MacConaill L, Garraway LA. Abstract LB-122: High-throughput tumor genomic profiling by massively parallel sequencing Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-122  0.622
2010 Beroukhim R, Meyerson M, Garraway L, Prensner J. Abstract 5759: The landscape of copy-number changes across multiple human cancer types Cancer Research. 70: 5759-5759. DOI: 10.1158/1538-7445.Am10-5759  0.7
2010 Barretina J, Caponigro G, Kim S, Stransky N, Venkhatesan K, Reddy V, Berger M, Morrissey M, Morais P, Meltzer J, Thibault J, Mahan S, Sonkin D, Che J, Raman P, ... Meyerson M, et al. Abstract 2620: The Cancer Cell Line Encyclopedia project: From integrative cancer genomics to personalized cancer therapy Cancer Research. 70: 2620-2620. DOI: 10.1158/1538-7445.Am10-2620  0.674
2010 Berger MF, Lawrence MS, Cibulskis K, Pflueger D, Demichelis F, Sougnez C, Onofrio RC, Ambrogio L, Fennell T, Parkin M, Carter SL, Saksena G, Sivachenko A, Voet D, Wilkinson J, ... Meyerson M, et al. Abstract 1139: Complete characterization of prostate cancer genomes by massively parallel sequencing Cancer Research. 70: 1139-1139. DOI: 10.1158/1538-7445.Am10-1139  0.475
2010 Stransky N, Venkhatesan K, Morrissey M, Barretina J, Raman P, Getz G, Berger M, Johannessen C, Callahan A, Morais P, Mahan S, Gupta S, Onofrio R, Sougnez C, Winckler W, ... Meyerson M, et al. Abstract 105: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia Cancer Research. 70: 105-105. DOI: 10.1158/1538-7445.Am10-105  0.654
2010 Stransky N, Venkatesan K, Barretina J, Caponigro G, Margolin A, Morrissey M, Raman P, Getz G, Berger M, Johannessen C, Callahan A, Morais P, Mahan S, Gupta S, Onofrio R, ... Meyerson M, et al. Abstract PR4: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-Pr4  0.629
2010 Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, Moustafa Z, Thomas RK, Greulich H, Schinzel A, Zaghlul S, Batt D, Ettenberg S, Meyerson M, Kung BSAL, et al. An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells (DOI:10.1016/j.ccr.2009.12.047) Cancer Cell. 17: 412. DOI: 10.1016/j.ccr.2010.03.014  0.476
2009 MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, ... Meyerson ML, et al. Profiling critical cancer gene mutations in clinical tumor samples. Plos One. 4: e7887. PMID 19924296 DOI: 10.1371/Journal.Pone.0007887  0.7
2009 Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, ... Meyerson M, et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature. 462: 108-12. PMID 19847166 DOI: 10.1038/Nature08460  0.691
2009 Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, ... Meyerson M, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature Genetics. 41: 1238-42. PMID 19801978 DOI: 10.1038/Ng.465  0.82
2009 Bass AJ, Meyerson M. Genome-wide association study in esophageal squamous cell carcinoma. Gastroenterology. 137: 1573-6. PMID 19789091 DOI: 10.1053/J.Gastro.2009.09.026  0.607
2009 Wagner PL, Perner S, Rickman DS, LaFargue CJ, Kitabayashi N, Johnstone SF, Weir BA, Meyerson M, Altorki NK, Rubin MA. In situ evidence of KRAS amplification and association with increased p21 levels in non-small cell lung carcinoma. American Journal of Clinical Pathology. 132: 500-5. PMID 19762526 DOI: 10.1309/Ajcpf10Zunsolifg  0.442
2009 Ramos AH, Dutt A, Mermel C, Perner S, Cho J, Lafargue CJ, Johnson LA, Stiedl AC, Tanaka KE, Bass AJ, Barretina J, Weir BA, Beroukhim R, Thomas RK, Minna JD, ... Meyerson M, et al. Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer Biology & Therapy. 8: 2042-50. PMID 19755855 DOI: 10.4161/Cbt.8.21.9764  0.818
2009 Dutt A, Salvesen HB, Greulich H, Sellers WR, Beroukhim R, Meyerson M. Somatic mutations are present in all members of the AKT family in endometrial carcinoma. British Journal of Cancer. 101: 1218-9; author reply. PMID 19738612 DOI: 10.1038/Sj.Bjc.6605301  0.802
2009 Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, O'Sullivan M, Lu J, Phillips LA, Lockhart VL, Shah SP, Tanwar PS, Mermel CH, Beroukhim R, Azam M, ... Meyerson M, et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nature Genetics. 41: 843-8. PMID 19483683 DOI: 10.1038/Ng.392  0.789
2009 Beroukhim R, Brunet JP, Di Napoli A, Mertz KD, Seeley A, Pires MM, Linhart D, Worrell RA, Moch H, Rubin MA, Sellers WR, Meyerson M, Linehan WM, Kaelin WG, Signoretti S. Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Research. 69: 4674-81. PMID 19470766 DOI: 10.1158/0008-5472.Can-09-0146  0.734
2009 Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, Li D, Ullrich R, Koker M, Fischer F, Shimamura T, Rauh D, Mermel C, Fischer S, Stückrath I, ... Meyerson M, et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. The Journal of Clinical Investigation. 119: 1727-40. PMID 19451690 DOI: 10.1172/Jci37127  0.825
2009 Sos ML, Koker M, Weir BA, Heynck S, Rabinovsky R, Zander T, Seeger JM, Weiss J, Fischer F, Frommolt P, Michel K, Peifer M, Mermel C, Girard L, Peyton M, ... Meyerson M, et al. PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. Cancer Research. 69: 3256-61. PMID 19351834 DOI: 10.1158/0008-5472.Can-08-4055  0.395
2009 Salvesen HB, Carter SL, Mannelqvist M, Dutt A, Getz G, Stefansson IM, Raeder MB, Sos ML, Engelsen IB, Trovik J, Wik E, Greulich H, Bø TH, Jonassen I, Thomas RK, ... Meyerson M, et al. Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 106: 4834-9. PMID 19261849 DOI: 10.1073/Pnas.0806514106  0.827
2009 Etemadmoghadam D, deFazio A, Beroukhim R, Mermel C, George J, Getz G, Tothill R, Okamoto A, Raeder MB, Harnett P, Lade S, Akslen LA, Tinker AV, Locandro B, Alsop K, ... Meyerson M, et al. Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1417-27. PMID 19193619 DOI: 10.1158/1078-0432.Ccr-08-1564  0.761
2009 Demichelis F, Setlur SR, Beroukhim R, Perner S, Korbel JO, Lafargue CJ, Pflueger D, Pina C, Hofer MD, Sboner A, Svensson MA, Rickman DS, Urban A, Snyder M, Meyerson M, et al. Distinct genomic aberrations associated with ERG rearranged prostate cancer. Genes, Chromosomes & Cancer. 48: 366-80. PMID 19156837 DOI: 10.1002/Gcc.20647  0.677
2009 Rozenblatt-Rosen O, Nagaike T, Francis JM, Kaneko S, Glatt KA, Hughes CM, LaFramboise T, Manley JL, Meyerson M. The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors. Proceedings of the National Academy of Sciences of the United States of America. 106: 755-60. PMID 19136632 DOI: 10.1073/Pnas.0812023106  0.305
2009 Perera SA, Li D, Shimamura T, Raso MG, Ji H, Chen L, Borgman CL, Zaghlul S, Brandstetter KA, Kubo S, Takahashi M, Chirieac LR, Padera RF, Bronson RT, Shapiro GI, ... Meyerson M, et al. HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 474-9. PMID 19122144 DOI: 10.1073/Pnas.0808930106  0.427
2009 Chiang DY, Getz G, Jaffe DB, O'Kelly MJ, Zhao X, Carter SL, Russ C, Nusbaum C, Meyerson M, Lander ES. High-resolution mapping of copy-number alterations with massively parallel sequencing. Nature Methods. 6: 99-103. PMID 19043412 DOI: 10.1038/Nmeth.1276  0.444
2009 Barletta JA, Perner S, Iafrate AJ, Yeap BY, Weir BA, Johnson LA, Johnson BE, Meyerson M, Rubin MA, Travis WD, Loda M, Chirieac LR. Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma. Journal of Cellular and Molecular Medicine. 13: 1977-86. PMID 19040416 DOI: 10.1111/J.1582-4934.2008.00594.X  0.318
2009 Perner S, Wagner PL, Soltermann A, LaFargue C, Tischler V, Weir BA, Weder W, Meyerson M, Giordano TJ, Moch H, Rubin MA. TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival. The Journal of Pathology. 217: 65-72. PMID 18932182 DOI: 10.1002/Path.2443  0.354
2009 MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, ... Meyerson ML, et al. Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples Plos One. 4. DOI: 10.1371/annotation/613c7509-e4c9-42ac-82fb-fc504400d9e0  0.531
2009 Greulich H, Chheda M, Chen T, Tanaka K, Dutt A, Wong K, Hahn W, Meyerson M. Abstract A199: Oncogenic and drug‐sensitive ERBB2 mutations in glioblastoma Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A199  0.753
2009 Cho J, Chen L, Sangji N, Du J, Okabe T, Yonesaka K, Francis JM, Flavin RJ, Yu S, Greulich HE, Johnson BE, Eck MJ, Jänne PA, Wong K, Meyerson M. Abstract A177: Cetuximab resistance associated with dimerization‐independence of oncogenic EGFR mutants Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A177  0.394
2009 Boehm JS, Cowley G, Weir B, Barretina J, Luo B, Cheung HW, Rusin S, Scott J, Derr A, Tsherniak A, Gopalakrishnan S, Tamayo P, Barbie D, Yang X, Piqani B, ... Meyerson M, et al. Abstract A23: An integrated platform for the functional annotation of the cancer genome Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A23  0.629
2009 Greulich H, Chheda M, Chen T, Tanaka K, Dutt A, Wong K, Hahn W, Meyerson M. Abstract A2: Oncogenic and drug‐sensitiveERBB2mutations in glioblastoma Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A2  0.756
2008 Wistuba II, Meyerson M. Chromosomal deletions and progression of premalignant lesions: Less is more Cancer Prevention Research. 1: 404-408. PMID 19138986 DOI: 10.1158/1940-6207.Capr-08-0177  0.31
2008 Luo B, Cheung HW, Subramanian A, Sharifnia T, Okamoto M, Yang X, Hinkle G, Boehm JS, Beroukhim R, Weir BA, Mermel C, Barbie DA, Awad T, Zhou X, Nguyen T, ... Meyerson M, et al. Highly parallel identification of essential genes in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 20380-5. PMID 19091943 DOI: 10.1073/Pnas.0810485105  0.773
2008 Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, ... Meyerson M, et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 455: 1069-75. PMID 18948947 DOI: 10.1038/Nature07423  0.815
2008 George RE, Sanda T, Hanna M, Fröhling S, Luther W, Zhang J, Ahn Y, Zhou W, London WB, McGrady P, Xue L, Zozulya S, Gregor VE, Webb TR, Gray NS, ... Meyerson M, et al. Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature. 455: 975-8. PMID 18923525 DOI: 10.1038/Nature07397  0.435
2008 Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, ... ... Meyerson M, et al. CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature. 455: 547-51. PMID 18794900 DOI: 10.1038/Nature07179  0.665
2008 Taylor BS, Barretina J, Socci ND, Decarolis P, Ladanyi M, Meyerson M, Singer S, Sander C. Functional copy-number alterations in cancer. Plos One. 3: e3179. PMID 18784837 DOI: 10.1371/Journal.Pone.0003179  0.443
2008 Chiang DY, Villanueva A, Hoshida Y, Peix J, Newell P, Minguez B, LeBlanc AC, Donovan DJ, Thung SN, Solé M, Tovar V, Alsinet C, Ramos AH, Barretina J, Roayaie S, ... ... Meyerson M, et al. Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Research. 68: 6779-88. PMID 18701503 DOI: 10.1158/0008-5472.Can-08-0742  0.584
2008 Shedden K, Taylor JM, Enkemann SA, Tsao MS, Yeatman TJ, Gerald WL, Eschrich S, Jurisica I, Giordano TJ, Misek DE, Chang AC, Zhu CQ, Strumpf D, Hanash S, ... Meyerson M, et al. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nature Medicine. 14: 822-7. PMID 18641660 DOI: 10.1038/Nm.1790  0.358
2008 Shimamura T, Li D, Ji H, Haringsma HJ, Liniker E, Borgman CL, Lowell AM, Minami Y, McNamara K, Perera SA, Zaghlul S, Thomas RK, Greulich H, Kobayashi S, Chirieac LR, ... ... Meyerson M, et al. Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance. Cancer Research. 68: 5827-38. PMID 18632637 DOI: 10.1158/0008-5472.Can-07-5428  0.366
2008 Koivunen JP, Kim J, Lee J, Rogers AM, Park JO, Zhao X, Naoki K, Okamoto I, Nakagawa K, Yeap BY, Meyerson M, Wong KK, Richards WG, Sugarbaker DJ, Johnson BE, et al. Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients. British Journal of Cancer. 99: 245-52. PMID 18594528 DOI: 10.1038/Sj.Bjc.6604469  0.429
2008 Koivunen JP, Mermel C, Zejnullahu K, Murphy C, Lifshits E, Holmes AJ, Choi HG, Kim J, Chiang D, Thomas R, Lee J, Richards WG, Sugarbaker DJ, Ducko C, Lindeman N, ... Meyerson M, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4275-83. PMID 18594010 DOI: 10.1158/1078-0432.Ccr-08-0168  0.404
2008 Dutt A, Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C, Nicoletti R, Winckler W, Grewal R, Hanna M, Wyhs N, Ziaugra L, Richter DJ, Trovik J, Engelsen IB, ... ... Meyerson M, et al. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 8713-7. PMID 18552176 DOI: 10.1073/Pnas.0803379105  0.813
2008 Li C, Beroukhim R, Weir BA, Winckler W, Garraway LA, Sellers WR, Meyerson M. Major copy proportion analysis of tumor samples using SNP arrays. Bmc Bioinformatics. 9: 204. PMID 18426588 DOI: 10.1186/1471-2105-9-204  0.795
2008 Li D, Ambrogio L, Shimamura T, Kubo S, Takahashi M, Chirieac LR, Padera RF, Shapiro GI, Baum A, Himmelsbach F, Rettig WJ, Meyerson M, Solca F, Greulich H, Wong KK. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 27: 4702-11. PMID 18408761 DOI: 10.1038/Onc.2008.109  0.423
2008 Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, et al. The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor. Genes & Development. 22: 884-93. PMID 18334619 DOI: 10.1101/Gad.1648608  0.372
2008 Loriaux MM, Levine RL, Tyner JW, Fröhling S, Scholl C, Stoffregen EP, Wernig G, Erickson H, Eide CA, Berger R, Bernard OA, Griffin JD, Stone RM, Lee B, Meyerson M, et al. High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia. Blood. 111: 4788-96. PMID 18252861 DOI: 10.1182/Blood-2007-07-101394  0.365
2008 Lin WM, Baker AC, Beroukhim R, Winckler W, Feng W, Marmion JM, Laine E, Greulich H, Tseng H, Gates C, Hodi FS, Dranoff G, Sellers WR, Thomas RK, Meyerson M, et al. Modeling genomic diversity and tumor dependency in malignant melanoma. Cancer Research. 68: 664-73. PMID 18245465 DOI: 10.1158/0008-5472.Can-07-2615  0.823
2008 Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proceedings of the National Academy of Sciences of the United States of America. 105: 2070-5. PMID 18227510 DOI: 10.1073/Pnas.0709662105  0.356
2008 Engelsen IB, Stefansson IM, Beroukhim R, Sellers WR, Meyerson M, Akslen LA, Salvesen HB. HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas. International Journal of Oncology. 32: 307-16. PMID 18202752 DOI: 10.3892/Ijo.32.2.307  0.745
2008 Swanson KD, Winter JM, Reis M, Bentires-Alj M, Greulich H, Grewal R, Hruban RH, Yeo CJ, Yassin Y, Iartchouk O, Montgomery K, Whitman SP, Caligiuri MA, Loh ML, Gilliland DG, ... Meyerson M, et al. SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients. Genes, Chromosomes & Cancer. 47: 253-9. PMID 18064648 DOI: 10.1002/Gcc.20527  0.462
2007 Engelman JA, Zejnullahu K, Gale CM, Lifshits E, Gonzales AJ, Shimamura T, Zhao F, Vincent PW, Naumov GN, Bradner JE, Althaus IW, Gandhi L, Shapiro GI, Nelson JM, Heymach JV, Meyerson M, et al. PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib. Cancer Research. 67: 11924-32. PMID 18089823 DOI: 10.1158/0008-5472.Can-07-1885  0.427
2007 Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, Du J, Kau T, Thomas RK, Shah K, Soto H, ... Meyerson M, et al. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proceedings of the National Academy of Sciences of the United States of America. 104: 20007-12. PMID 18077431 DOI: 10.1073/Pnas.0710052104  0.755
2007 Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, ... Meyerson M, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 450: 893-8. PMID 17982442 DOI: 10.1038/Nature06358  0.818
2007 Getz G, Höfling H, Mesirov JP, Golub TR, Meyerson M, Tibshirani R, Lander ES. Comment on "The consensus coding sequences of human breast and colorectal cancers". Science (New York, N.Y.). 317: 1500. PMID 17872428 DOI: 10.1126/Science.1138764  0.378
2007 Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, ... Meyerson M, et al. LKB1 modulates lung cancer differentiation and metastasis. Nature. 448: 807-10. PMID 17676035 DOI: 10.1038/Nature06030  0.453
2007 Meyerson M. Cancer: Broken genes in solid tumours Nature. 448: 545-546. PMID 17671492 DOI: 10.1038/448545A  0.435
2007 Li D, Shimamura T, Ji H, Chen L, Haringsma HJ, McNamara K, Liang MC, Perera SA, Zaghlul S, Borgman CL, Kubo S, Takahashi M, Sun Y, Chirieac LR, Padera RF, ... Meyerson ML, et al. Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy. Cancer Cell. 12: 81-93. PMID 17613438 DOI: 10.1016/J.Ccr.2007.06.005  0.307
2007 Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, ... Meyerson M, et al. Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell. 129: 1065-79. PMID 17574021 DOI: 10.1016/J.Cell.2007.03.052  0.585
2007 Yuza Y, Glatt KA, Jiang J, Greulich H, Minami Y, Woo MS, Shimamura T, Shapiro G, Lee JC, Ji H, Feng W, Chen TH, Yanagisawa H, Wong KK, Meyerson M. Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors. Cancer Biology & Therapy. 6: 661-7. PMID 17495523 DOI: 10.4161/Cbt.6.5.4003  0.427
2007 Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 11: 217-27. PMID 17349580 DOI: 10.1016/J.Ccr.2006.12.017  0.374
2007 George RE, Attiyeh EF, Li S, Moreau LA, Neuberg D, Li C, Fox EA, Meyerson M, Diller L, Fortina P, Look AT, Maris JM. Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays. Plos One. 2: e255. PMID 17327916 DOI: 10.1371/Journal.Pone.0000255  0.315
2007 Minami Y, Shimamura T, Shah K, LaFramboise T, Glatt KA, Liniker E, Borgman CL, Haringsma HJ, Feng W, Weir BA, Lowell AM, Lee JC, Wolf J, Shapiro GI, Wong KK, Meyerson M, et al. The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272. Oncogene. 26: 5023-7. PMID 17311002 DOI: 10.1038/Sj.Onc.1210292  0.46
2007 Thomas RK, Baker AC, Debiasi RM, Winckler W, Laframboise T, Lin WM, Wang M, Feng W, Zander T, MacConaill L, Macconnaill LE, Lee JC, Nicoletti R, Hatton C, Goyette M, ... Meyerson M, et al. High-throughput oncogene mutation profiling in human cancer. Nature Genetics. 39: 347-51. PMID 17293865 DOI: 10.1038/Ng1975  0.829
2007 Sequist LV, Joshi VA, Jänne PA, Muzikansky A, Fidias P, Meyerson M, Haber DA, Kucherlapati R, Johnson BE, Lynch TJ. Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. The Oncologist. 12: 90-8. PMID 17285735 DOI: 10.1634/Theoncologist.12-1-90  0.403
2007 Jackman DM, Yeap BY, Lindeman NI, Fidias P, Rabin MS, Temel J, Skarin AT, Meyerson M, Holmes AJ, Borras AM, Freidlin B, Ostler PA, Lucca J, Lynch TJ, Johnson BE, et al. Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 760-6. PMID 17228019 DOI: 10.1200/Jco.2006.07.5754  0.369
2007 Beroukhim R, Lin M, Park Y, Hao K, Zhao X, Garraway LA, Fox EA, Hochberg EP, Mellinghoff IK, Hofer MD, Descazeaud A, Rubin MA, Meyerson M, Wong WH, Sellers WR, et al. Correction: Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays Plos Computational Biology. 3: e40. DOI: 10.1371/Journal.Pcbi.0030040  0.685
2007 Thomas RK, Meyerson M. C7-06: Translational lung cancer genomics Journal of Thoracic Oncology. 2: S381-S382. DOI: 10.1097/01.Jto.0000283234.99206.70  0.401
2007 Thomas RK, Baker AC, DeBiasi RM, Winckler W, LaFramboise T, Lin WM, Wang M, Feng W, Zander T, MacConnaill LE, Lee JC, Nicoletti R, Hatton C, Goyette M, Girard L, ... Meyerson M, et al. Erratum: Corrigendum: High-throughput oncogene mutation profiling in human cancer Nature Genetics. 39: 567-567. DOI: 10.1038/Ng0407-567A  0.815
2006 Lee JC, Vivanco I, Beroukhim R, Huang JH, Feng WL, DeBiasi RM, Yoshimoto K, King JC, Nghiemphu P, Yuza Y, Xu Q, Greulich H, Thomas RK, Paez JG, Peck TC, ... ... Meyerson M, et al. Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. Plos Medicine. 3: e485. PMID 17177598 DOI: 10.1371/Journal.Pmed.0030485  0.732
2006 Kobayashi S, Shimamura T, Monti S, Steidl U, Hetherington CJ, Lowell AM, Golub T, Meyerson M, Tenen DG, Shapiro GI, Halmos B. Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling. Cancer Research. 66: 11389-98. PMID 17145885 DOI: 10.1158/0008-5472.Can-06-2318  0.396
2006 Hayes DN, Monti S, Parmigiani G, Gilks CB, Naoki K, Bhattacharjee A, Socinski MA, Perou C, Meyerson M. Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 5079-90. PMID 17075127 DOI: 10.1200/Jco.2005.05.1748  0.358
2006 MacConaill LE, Hughes CM, Rozenblatt-Rosen O, Nannepaga S, Meyerson M. Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583. Molecular Cancer Research : McR. 4: 793-801. PMID 17050672 DOI: 10.1158/1541-7786.Mcr-06-0123  0.341
2006 Perner S, Demichelis F, Beroukhim R, Schmidt FH, Mosquera JM, Setlur S, Tchinda J, Tomlins SA, Hofer MD, Pienta KG, Kuefer R, Vessella R, Sun XW, Meyerson M, Lee C, et al. TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. Cancer Research. 66: 8337-41. PMID 16951139 DOI: 10.1158/0008-5472.Can-06-1482  0.735
2006 Sequist LV, Joshi VA, Jänne PA, Bell DW, Fidias P, Lindeman NI, Louis DN, Lee JC, Mark EJ, Longtine J, Verlander P, Kucherlapati R, Meyerson M, Haber DA, Johnson BE, et al. Epidermal growth factor receptor mutation testing in the care of lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4403s-4408s. PMID 16857818 DOI: 10.1158/1078-0432.Ccr-06-0099  0.417
2006 Thomas RK, Weir B, Meyerson M. Genomic approaches to lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4384s-4391s. PMID 16857815 DOI: 10.1158/1078-0432.Ccr-06-0098  0.493
2006 Lynch TJ, Adjei AA, Bunn PA, Eisen TG, Engelman J, Goss GD, Haber DA, Heymach JV, Jänne PA, Johnson BE, Johnson DH, Lilenbaum RC, Meyerson M, Sandler AB, Sequist LV, et al. Summary statement: novel agents in the treatment of lung cancer: advances in epidermal growth factor receptor-targeted agents. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4365s-4371s. PMID 16857812 DOI: 10.1158/1078-0432.Ccr-06-1005  0.61
2006 Jackman DM, Yeap BY, Sequist LV, Lindeman N, Holmes AJ, Joshi VA, Bell DW, Huberman MS, Halmos B, Rabin MS, Haber DA, Lynch TJ, Meyerson M, Johnson BE, Jänne PA. Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3908-14. PMID 16818686 DOI: 10.1158/1078-0432.Ccr-06-0462  0.396
2006 Shimamura T, Ji H, Minami Y, Thomas RK, Lowell AM, Shah K, Greulich H, Glatt KA, Meyerson M, Shapiro GI, Wong KK. Non-small-cell lung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272. Cancer Research. 66: 6487-91. PMID 16818618 DOI: 10.1158/0008-5472.Can-06-0971  0.426
2006 Thomas RK, Nickerson E, Simons JF, Jänne PA, Tengs T, Yuza Y, Garraway LA, LaFramboise T, Lee JC, Shah K, O'Neill K, Sasaki H, Lindeman N, Wong KK, Borras AM, ... Meyerson M, et al. Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing. Nature Medicine. 12: 852-5. PMID 16799556 DOI: 10.1038/Nm1437  0.633
2006 Costa DB, Dayaram T, D'Alo F, Wouters BJ, Tenen DG, Meyerson M, Tsao MS, Halmos B. C/EBP alpha mutations in lung cancer. Lung Cancer (Amsterdam, Netherlands). 53: 253-4. PMID 16765476 DOI: 10.1016/J.Lungcan.2006.04.011  0.372
2006 Beroukhim R, Lin M, Park Y, Hao K, Zhao X, Garraway LA, Fox EA, Hochberg EP, Mellinghoff IK, Hofer MD, Descazeaud A, Rubin MA, Meyerson M, Wong WH, Sellers WR, et al. Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays. Plos Computational Biology. 2: e41. PMID 16699594 DOI: 10.1371/Journal.Pcbi.0020041  0.715
2006 Ji H, Zhao X, Yuza Y, Shimamura T, Li D, Protopopov A, Jung BL, McNamara K, Xia H, Glatt KA, Thomas RK, Sasaki H, Horner JW, Eck M, Mitchell A, ... Meyerson M, et al. Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 103: 7817-22. PMID 16672372 DOI: 10.1073/Pnas.0510284103  0.429
2006 Alvarez JV, Greulich H, Sellers WR, Meyerson M, Frank DA. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. Cancer Research. 66: 3162-8. PMID 16540667 DOI: 10.1158/0008-5472.Can-05-3757  0.617
2006 Jänne PA, Borras AM, Kuang Y, Rogers AM, Joshi VA, Liyanage H, Lindeman N, Lee JC, Halmos B, Maher EA, Distel RJ, Meyerson M, Johnson BE. A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 751-8. PMID 16467085 DOI: 10.1158/1078-0432.Ccr-05-2047  0.41
2006 Sequist LV, Joshi VA, Jänne PA, Fidias P, Muzikansky A, Meyerson M, Haber DA, Kucherlapati R, Johnson BE, Lynch TJ. Epidermal growth factor receptor (EGFR) mutation testing in non-small cell lung cancer (NSCLC) patients (pts) Journal of Clinical Oncology. 24: 7177-7177. DOI: 10.1200/Jco.2006.24.18_Suppl.7177  0.345
2006 Thomas RK, Nickerson E, Simons JF, Jänne PA, Tengs T, Yuza Y, Garraway LA, LaFramboise T, Lee JC, Shah K, O'Neill K, Sasaki H, Lindeman N, Wong KK, Borras AM, ... Meyerson M, et al. Erratum: Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing (Nature Medicine (2006) 12 (852-855)) Nature Medicine. 12. DOI: 10.1038/Nm1006-1220A  0.607
2005 Thomas RK, Greulich H, Yuza Y, Lee JC, Tengs T, Feng W, Chen TH, Nickerson E, Simons J, Egholm M, Rothberg JM, Sellers WR, Meyerson ML. Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors. Cold Spring Harbor Symposia On Quantitative Biology. 70: 73-81. PMID 16869740 DOI: 10.1101/Sqb.2005.70.056  0.6
2005 Garraway LA, Weir BA, Zhao X, Widlund H, Beroukhim R, Berger A, Rimm D, Rubin MA, Fisher DE, Meyerson ML, Sellers WR. "Lineage addiction" in human cancer: lessons from integrated genomics. Cold Spring Harbor Symposia On Quantitative Biology. 70: 25-34. PMID 16869735 DOI: 10.1101/Sqb.2005.70.016  0.76
2005 LaFramboise T, Weir BA, Zhao X, Beroukhim R, Li C, Harrington D, Sellers WR, Meyerson M. Allele-specific amplification in cancer revealed by SNP array analysis. Plos Computational Biology. 1: e65. PMID 16322765 DOI: 10.1371/Journal.Pcbi.0010065  0.717
2005 Yokoyama A, Somervaille TC, Smith KS, Rozenblatt-Rosen O, Meyerson M, Cleary ML. The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell. 123: 207-18. PMID 16239140 DOI: 10.1016/J.Cell.2005.09.025  0.404
2005 Jiang J, Greulich H, Jänne PA, Sellers WR, Meyerson M, Griffin JD. Epidermal growth factor-independent transformation of Ba/F3 cells with cancer-derived epidermal growth factor receptor mutants induces gefitinib-sensitive cell cycle progression. Cancer Research. 65: 8968-74. PMID 16204070 DOI: 10.1158/0008-5472.Can-05-1829  0.571
2005 Karnik SK, Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Xiong Y, Meyerson M, Kim SK. Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. Proceedings of the National Academy of Sciences of the United States of America. 102: 14659-64. PMID 16195383 DOI: 10.1073/Pnas.0503484102  0.329
2005 Greulich H, Chen TH, Feng W, Jänne PA, Alvarez JV, Zappaterra M, Bulmer SE, Frank DA, Hahn WC, Sellers WR, Meyerson M. Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants. Plos Medicine. 2: e313. PMID 16187797 DOI: 10.1371/Journal.Pmed.0020313  0.662
2005 Kobayashi S, Ji H, Yuza Y, Meyerson M, Wong KK, Tenen DG, Halmos B. An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor Cancer Research. 65: 7096-7101. PMID 16103058 DOI: 10.1158/0008-5472.Can-05-1346  0.4
2005 Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, et al. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature. 436: 117-22. PMID 16001072 DOI: 10.1038/Nature03664  0.765
2005 Zhao X, Weir BA, LaFramboise T, Lin M, Beroukhim R, Garraway L, Beheshti J, Lee JC, Naoki K, Richards WG, Sugarbaker D, Chen F, Rubin MA, Jänne PA, Girard L, ... ... Meyerson M, et al. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Research. 65: 5561-70. PMID 15994928 DOI: 10.1158/0008-5472.Can-04-4603  0.735
2005 Meyerson M, Carbone D. Genomic and proteomic profiling of lung cancers: Lung cancer classification in the age of targeted therapy Journal of Clinical Oncology. 23: 3219-3226. PMID 15886309 DOI: 10.1200/Jco.2005.15.511  0.436
2005 Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, Boggon TJ, Wlodarska I, Clark JJ, Moore S, Adelsperger J, Koo S, Lee JC, Gabriel S, Mercher T, ... ... Meyerson M, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 7: 387-97. PMID 15837627 DOI: 10.1016/J.Ccr.2005.03.023  0.571
2005 Sellers WR, Meyerson M. EGFR gene mutations: a call for global x global views of cancer. Journal of the National Cancer Institute. 97: 326-8. PMID 15741561 DOI: 10.1093/Jnci/Dji079  0.65
2005 Kobayashi S, Boggon TJ, Dayaram T, Jänne PA, Kocher O, Meyerson M, Johnson BE, Eck MJ, Tenen DG, Halmos B. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine. 352: 786-92. PMID 15728811 DOI: 10.1056/Nejmoa044238  0.442
2005 Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 102: 749-54. PMID 15640349 DOI: 10.1073/Pnas.0408836102  0.344
2005 Sequist L, Janne P, Joshi V, Fidias P, Verlander P, Meyerson M, Haber D, Johnson B, Kucherlapati R, Lynch T. PD-156 The Massachusetts General Hospital/Dana-Farber Cancer Institute/Harvard Medical School Partners HealthCare Center for genetics and genomics experience with clinical testing for somatic EGFR mutations in NSCLC patients Lung Cancer. 49: S112. DOI: 10.1016/S0169-5002(05)80489-1  0.373
2004 Bentires-Alj M, Paez JG, David FS, Keilhack H, Halmos B, Naoki K, Maris JM, Richardson A, Bardelli A, Sugarbaker DJ, Richards WG, Du J, Girard L, Minna JD, Loh ML, ... ... Meyerson M, et al. Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia. Cancer Research. 64: 8816-20. PMID 15604238 DOI: 10.1158/0008-5472.Can-04-1923  0.598
2004 Weir B, Zhao X, Meyerson M. Somatic alterations in the human cancer genome Cancer Cell. 6: 433-438. PMID 15542426 DOI: 10.1016/J.Ccr.2004.11.004  0.513
2004 Tracy S, Mukohara T, Hansen M, Meyerson M, Johnson BE, Jänne PA. Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255. Cancer Research. 64: 7241-4. PMID 15492241 DOI: 10.1158/0008-5472.Can-04-1905  0.338
2004 Krop I, Player A, Tablante A, Taylor-Parker M, Lahti-Domenici J, Fukuoka J, Batra SK, Papadopoulos N, Richards WG, Sugarbaker DJ, Wright RL, Shim J, Stamey TA, Sellers WR, Loda M, ... Meyerson M, et al. Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types. Molecular Cancer Research : McR. 2: 489-94. PMID 15383627  0.534
2004 Tengs T, LaFramboise T, Den RB, Hayes DN, Zhang J, DebRoy S, Gentleman RC, O'Neill K, Birren B, Meyerson M. Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments. Nucleic Acids Research. 32: e121. PMID 15329383 DOI: 10.1093/Nar/Gnh120  0.303
2004 Dubinett SM, Elashoff D, Meyerson M. Assessing prognosis in non-small-cell lung cancer: Avenues to a more complete picture? Journal of Clinical Oncology. 22: 3209-3211. PMID 15249586 DOI: 10.1200/Jco.2004.05.931  0.366
2004 Jiang J, Paez JG, Lee JC, Bo R, Stone RM, DeAngelo DJ, Galinsky I, Wolpin BM, Jonasova A, Herman P, Fox EA, Boggon TJ, Eck MJ, Weisberg E, Griffin JD, ... ... Meyerson M, et al. Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AML. Blood. 104: 1855-8. PMID 15178581 DOI: 10.1182/Blood-2004-02-0712  0.566
2004 Paez JG, Lin M, Beroukhim R, Lee JC, Zhao X, Richter DJ, Gabriel S, Herman P, Sasaki H, Altshuler D, Li C, Meyerson M, Sellers WR. Genome coverage and sequence fidelity of phi29 polymerase-based multiple strand displacement whole genome amplification. Nucleic Acids Research. 32: e71. PMID 15150323 DOI: 10.1093/Nar/Gnh069  0.735
2004 Zhao X, Li C, Paez JG, Chin K, Jänne PA, Chen TH, Girard L, Minna J, Christiani D, Leo C, Gray JW, Sellers WR, Meyerson M. An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Research. 64: 3060-71. PMID 15126342 DOI: 10.1158/0008-5472.Can-03-3308  0.614
2004 Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, Herman P, Kaye FJ, Lindeman N, Boggon TJ, Naoki K, Sasaki H, Fujii Y, Eck MJ, Sellers WR, ... Meyerson M, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science (New York, N.Y.). 304: 1497-500. PMID 15118125 DOI: 10.1126/Science.1099314  0.624
2004 Jänne PA, Li C, Zhao X, Girard L, Chen TH, Minna J, Christiani DC, Johnson BE, Meyerson M. High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines. Oncogene. 23: 2716-26. PMID 15048096 DOI: 10.1038/Sj.Onc.1207329  0.424
2004 Hughes CM, Rozenblatt-Rosen O, Milne TA, Copeland TD, Levine SS, Lee JC, Hayes DN, Shanmugam KS, Bhattacharjee A, Biondi CA, Kay GF, Hayward NK, Hess JL, Meyerson M. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Molecular Cell. 13: 587-97. PMID 14992727 DOI: 10.1016/S1097-2765(04)00081-4  0.317
2004 Meyerson M, Franklin WA, Kelley MJ. Molecular Classification and Molecular Genetics of Human Lung Cancers Seminars in Oncology. 31: 4-19. PMID 14981576 DOI: 10.1053/J.Seminoncol.2003.12.009  0.442
2004 Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, Wolfsberg TG, Umayam L, Lee JC, Hughes CM, Shanmugam KS, Bhattacharjee A, Meyerson M, Collins FS. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 1892-7. PMID 14769924 DOI: 10.1073/Pnas.0308698100  0.311
2004 Wang ZC, Lin M, Wei LJ, Li C, Miron A, Lodeiro G, Harris L, Ramaswamy S, Tanenbaum DM, Meyerson M, Iglehart JD, Richardson A. Loss of heterozygosity and its correlation with expression profiles in subclasses of invasive breast cancers. Cancer Research. 64: 64-71. PMID 14729609 DOI: 10.1158/0008-5472.Can-03-2570  0.396
2003 Lieberfarb ME, Lin M, Lechpammer M, Li C, Tanenbaum DM, Febbo PG, Wright RL, Shim J, Kantoff PW, Loda M, Meyerson M, Sellers WR. Genome-wide loss of heterozygosity analysis from laser capture microdissected prostate cancer using single nucleotide polymorphic allele (SNP) arrays and a novel bioinformatics platform dChipSNP. Cancer Research. 63: 4781-5. PMID 12941794  0.52
2003 Xu Y, Stange-Thomann N, Weber G, Bo R, Dodge S, David RG, Foley K, Beheshti J, Harris NL, Birren B, Lander ES, Meyerson M. Pathogen discovery from human tissue by sequence-based computational subtraction. Genomics. 81: 329-35. PMID 12659816 DOI: 10.1016/S0888-7543(02)00043-5  0.303
2002 Naoki K, Chen TH, Richards WG, Sugarbaker DJ, Meyerson M. Missense mutations of the BRAF gene in human lung adenocarcinoma. Cancer Research. 62: 7001-3. PMID 12460919  0.351
2002 Weber G, Shendure J, Tanenbaum DM, Church GM, Meyerson M. Identification of foreign gene sequences by transcript filtering against the human genome. Nature Genetics. 30: 141-2. PMID 11788827 DOI: 10.1038/Ng818  0.332
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