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William Erwin Paul - Publications

Affiliations: 
National Institute of Health, Bethesda, MD, United States 
Area:
immunology
Website:
https://doi.org/10.4049/jimmunol.1590025
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303 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lee PH, Yamamoto TN, Gurusamy D, Sukumar M, Yu Z, Hu-Li J, Kawabe T, Gangaplara A, Kishton RJ, Henning AN, Vodnala SK, Germain RN, Paul WE, Restifo NP. Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells. The Journal of Experimental Medicine. PMID 31405895 DOI: 10.1084/Jem.20181218  0.32
2017 Kawabe T, Jankovic D, Kawabe S, Huang Y, Lee PH, Yamane H, Zhu J, Sher A, Germain RN, Paul WE. Memory-phenotype CD4(+) T cells spontaneously generated under steady-state conditions exert innate TH1-like effector function. Science Immunology. 2. PMID 28783663 DOI: 10.1126/Sciimmunol.Aam9304  0.358
2017 Hogg A, Sui Y, Ben-Sasson SZ, Paul WE, Berzofsky JA. Role of CD4 T cell helper subsets in immune response and deviation of CD8 T cells in mice. European Journal of Immunology. PMID 28741316 DOI: 10.1002/eji.201747091  0.335
2016 Caucheteux SM, Hu-Li J, Mohammed RN, Ager A, Paul WE. Cytokine regulation of lung Th17 response to airway immunization using LPS adjuvant. Mucosal Immunology. PMID 27328989 DOI: 10.1038/Mi.2016.54  0.378
2016 Hojyo S, Sarkander J, Männe C, Mursell M, Hanazawa A, Zimmel D, Zhu J, Paul WE, Fillatreau S, Löhning M, Radbruch A, Tokoyoda K. B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow. Frontiers in Immunology. 7: 26. PMID 26870041 DOI: 10.3389/Fimmu.2016.00026  0.304
2015 Guo L, Huang Y, Chen X, Hu-Li J, Urban JF, Paul WE. Innate immunological function of TH2 cells in vivo. Nature Immunology. PMID 26322482 DOI: 10.1038/ni.3244  0.385
2015 Grossman Z, Paul WE. Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function. Annual Review of Immunology. 33: 677-713. PMID 25665077 DOI: 10.1146/Annurev-Immunol-032712-100027  0.324
2015 Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegazy AN, Duque-Correa MA, Zhang Q, Vainshtein Y, Radbruch A, Kaufmann SH, Paul WE, Höfer T, Löhning M. Individual T helper cells have a quantitative cytokine memory. Immunity. 42: 108-22. PMID 25607461 DOI: 10.1016/J.Immuni.2014.12.018  0.31
2015 Dewas C, Chen X, Honda T, Junttila I, Linton J, Udey MC, Porcella SF, Sturdevant DE, Feigenbaum L, Koo L, Williams J, Paul WE. TSLP expression: analysis with a ZsGreen TSLP reporter mouse. Journal of Immunology (Baltimore, Md. : 1950). 194: 1372-80. PMID 25539812 DOI: 10.4049/jimmunol.1400519  0.34
2015 Huang Y, Guo L, Qiu J, Chen X, Hu-Li J, Siebenlist U, Williamson PR, Urban JF, Paul WE. IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells. Nature Immunology. 16: 161-9. PMID 25531830 DOI: 10.1038/ni.3078  0.392
2014 Paul WE, Grossman Z. Pathogen-sensing and regulatory T cells: integrated regulators of immune responses. Cancer Immunology Research. 2: 503-9. PMID 24894087 DOI: 10.1158/2326-6066.Cir-14-0046  0.318
2014 Meylan F, Hawley ET, Barron L, Barlow JL, Penumetcha P, Pelletier M, Sciumè G, Richard AC, Hayes ET, Gomez-Rodriguez J, Chen X, Paul WE, Wynn TA, McKenzie AN, Siegel RM. The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells. Mucosal Immunology. 7: 958-68. PMID 24368564 DOI: 10.1038/Mi.2013.114  0.33
2013 Paul WE, Milner JD, Grossman Z. Pathogen-sensing, regulatory T cells, and responsiveness-tuning collectively regulate foreign- and self-antigen mediated T-cell responses. Cold Spring Harbor Symposia On Quantitative Biology. 78: 265-76. PMID 24100584 DOI: 10.1101/Sqb.2013.78.020198  0.322
2013 Ben-Sasson SZ, Wang K, Cohen J, Paul WE. IL-1β strikingly enhances antigen-driven CD4 and CD8 T-cell responses. Cold Spring Harbor Symposia On Quantitative Biology. 78: 117-24. PMID 24092469 DOI: 10.1101/sqb.2013.78.021246  0.354
2013 Guo L, Martens C, Bruno D, Porcella SF, Yamane H, Caucheteux SM, Zhu J, Paul WE. Lipid phosphatases identified by screening a mouse phosphatase shRNA library regulate T-cell differentiation and protein kinase B AKT signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: E1849-56. PMID 23630283 DOI: 10.1073/pnas.1305070110  0.313
2013 Roediger B, Kyle R, Yip KH, Sumaria N, Guy TV, Kim BS, Mitchell AJ, Tay SS, Jain R, Forbes-Blom E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, et al. Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nature Immunology. 14: 564-73. PMID 23603794 DOI: 10.1038/Ni.2584  0.352
2013 Ben-Sasson SZ, Hogg A, Hu-Li J, Wingfield P, Chen X, Crank M, Caucheteux S, Ratner-Hurevich M, Berzofsky JA, Nir-Paz R, Paul WE. IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells. The Journal of Experimental Medicine. 210: 491-502. PMID 23460726 DOI: 10.1084/jem.20122006  0.397
2013 Yamane H, Paul WE. Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets. Immunological Reviews. 252: 12-23. PMID 23405892 DOI: 10.1111/imr.12032  0.356
2013 Howard M, Farrar J, Hilfiker M, Johnson B, Takatsu K, Hamaoka T, Paul WE. Pillars article: Identification of a T cell-derived B cell growth factor distinct from interleukin 2. J. Exp. Med. 1982. 155: 914-923. Journal of Immunology (Baltimore, Md. : 1950). 190: 864-73. PMID 23335802 DOI: 10.4049/jimmunol.1203368  0.306
2013 Meylan F, Hawley E, Barron L, Barlow J, Tan C, Penumetcha P, Richard A, Chen X, Paul WE, Wynn TA, Gery I, McKenzie A, Siegel RM. 180 Cytokine. 63: 285. DOI: 10.1016/J.Cyto.2013.06.183  0.367
2012 Yamane H, Paul WE. Cytokines of the γ(c) family control CD4+ T cell differentiation and function. Nature Immunology. 13: 1037-44. PMID 23080204 DOI: 10.1038/ni.2431  0.344
2012 Zhu J, Jankovic D, Oler AJ, Wei G, Sharma S, Hu G, Guo L, Yagi R, Yamane H, Punkosdy G, Feigenbaum L, Zhao K, Paul WE. The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses. Immunity. 37: 660-73. PMID 23041064 DOI: 10.1016/J.Immuni.2012.09.007  0.31
2012 Guo L, Junttila IS, Paul WE. Cytokine-induced cytokine production by conventional and innate lymphoid cells. Trends in Immunology. 33: 598-606. PMID 22959641 DOI: 10.1016/J.It.2012.07.006  0.39
2012 Yamane H, Paul WE. Memory CD4+ T cells: fate determination, positive feedback and plasticity. Cellular and Molecular Life Sciences : Cmls. 69: 1577-83. PMID 22481436 DOI: 10.1007/s00018-012-0966-9  0.327
2011 Younes SA, Punkosdy G, Caucheteux S, Chen T, Grossman Z, Paul WE. Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells. Plos Biology. 9: e1001171. PMID 22022231 DOI: 10.1371/Journal.Pbio.1001171  0.464
2011 Wohlfert EA, Grainger JR, Bouladoux N, Konkel JE, Oldenhove G, Ribeiro CH, Hall JA, Yagi R, Naik S, Bhairavabhotla R, Paul WE, Bosselut R, Wei G, Zhao K, Oukka M, et al. GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice. The Journal of Clinical Investigation. 121: 4503-15. PMID 21965331 DOI: 10.1172/Jci57456  0.407
2011 Wei G, Abraham BJ, Yagi R, Jothi R, Cui K, Sharma S, Narlikar L, Northrup DL, Tang Q, Paul WE, Zhu J, Zhao K. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity. 35: 299-311. PMID 21867929 DOI: 10.1016/J.Immuni.2011.08.007  0.407
2011 Ben-Sasson SZ, Caucheteux S, Crank M, Hu-Li J, Paul WE. IL-1 acts on T cells to enhance the magnitude of in vivo immune responses. Cytokine. 56: 122-5. PMID 21843950 DOI: 10.1016/j.cyto.2011.07.006  0.369
2011 Yagi R, Zhu J, Paul WE. An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation. International Immunology. 23: 415-20. PMID 21632975 DOI: 10.1093/Intimm/Dxr029  0.348
2011 Bocharov G, Quiel J, Luzyanina T, Alon H, Chiglintsev E, Chereshnev V, Meier-Schellersheim M, Paul WE, Grossman Z. Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number. Proceedings of the National Academy of Sciences of the United States of America. 108: 3318-23. PMID 21292990 DOI: 10.1073/Pnas.1019706108  0.344
2011 Quiel J, Caucheteux S, Laurence A, Singh NJ, Bocharov G, Ben-Sasson SZ, Grossman Z, Paul WE. Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number. Proceedings of the National Academy of Sciences of the United States of America. 108: 3312-7. PMID 21292989 DOI: 10.1073/Pnas.1018525108  0.329
2011 van Panhuys N, Prout M, Forbes E, Min B, Paul WE, Le Gros G. Basophils are the major producers of IL-4 during primary helminth infection. Journal of Immunology (Baltimore, Md. : 1950). 186: 2719-28. PMID 21270410 DOI: 10.4049/Jimmunol.1000940  0.421
2010 Zhu J, Paul WE. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunological Reviews. 238: 247-62. PMID 20969597 DOI: 10.1111/J.1600-065X.2010.00951.X  0.442
2010 Khandanpour C, Sharif-Askari E, Vassen L, Gaudreau MC, Zhu J, Paul WE, Okayama T, Kosan C, Möröy T. Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells. Blood. 116: 5149-61. PMID 20826720 DOI: 10.1182/Blood-2010-04-280305  0.318
2010 Milner JD, Fazilleau N, McHeyzer-Williams M, Paul W. Cutting edge: lack of high affinity competition for peptide in polyclonal CD4+ responses unmasks IL-4 production. Journal of Immunology (Baltimore, Md. : 1950). 184: 6569-73. PMID 20495070 DOI: 10.4049/Jimmunol.1000674  0.327
2010 Paul WE, Zhu J. How are T(H)2-type immune responses initiated and amplified? Nature Reviews. Immunology. 10: 225-35. PMID 20336151 DOI: 10.1038/Nri2735  0.463
2010 Zhu J, Yamane H, Paul WE. Differentiation of effector CD4 T cell populations (*). Annual Review of Immunology. 28: 445-89. PMID 20192806 DOI: 10.1146/Annurev-Immunol-030409-101212  0.431
2010 Zhu J, Paul WE. CD4+ T cell plasticity-Th2 cells join the crowd. Immunity. 32: 11-3. PMID 20152167 DOI: 10.1016/J.Immuni.2010.01.001  0.429
2010 Zhu J, Paul WE. Heterogeneity and plasticity of T helper cells. Cell Research. 20: 4-12. PMID 20010916 DOI: 10.1038/Cr.2009.138  0.479
2010 Paul W. CD4 T cells: fates and functions (ML05) International Immunology. 22: ii1-ii1. DOI: 10.1093/Intimm/Dxq098  0.361
2009 Guo L, Wei G, Zhu J, Liao W, Leonard WJ, Zhao K, Paul W. IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 13463-8. PMID 19666510 DOI: 10.1073/Pnas.0906988106  0.316
2009 Ben-Sasson SZ, Hu-Li J, Quiel J, Cauchetaux S, Ratner M, Shapira I, Dinarello CA, Paul WE. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 106: 7119-24. PMID 19359475 DOI: 10.1073/Pnas.0902745106  0.339
2009 Zhu J, Davidson TS, Wei G, Jankovic D, Cui K, Schones DE, Guo L, Zhao K, Shevach EM, Paul WE. Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells. The Journal of Experimental Medicine. 206: 329-41. PMID 19188499 DOI: 10.1084/Jem.20081666  0.443
2009 Wei G, Wei L, Zhu J, Zang C, Hu-Li J, Yao Z, Cui K, Kanno Y, Roh TY, Watford WT, Schones DE, Peng W, Sun HW, Paul WE, O'Shea JJ, et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity. 30: 155-67. PMID 19144320 DOI: 10.1016/J.Immuni.2008.12.009  0.445
2008 Heller NM, Qi X, Junttila IS, Shirey KA, Vogel SN, Paul WE, Keegan AD. Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages. Science Signaling. 1: ra17. PMID 19109239 DOI: 10.1126/Scisignal.1164795  0.356
2008 Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, et al. Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii. The Journal of Experimental Medicine. 205: 2803-12. PMID 19001140 DOI: 10.1084/Jem.20081461  0.303
2008 Paul WE. Th1 fate determination in CD4+ T cells: notice is served of the importance of IL-12! Journal of Immunology (Baltimore, Md. : 1950). 181: 4435-6. PMID 18802043  0.308
2008 Milner J, Paul WE. Limited T-cell receptor diversity predisposes to Th2 immunopathology: involvement of Tregs and conventional CD4 T cells. Journal of Clinical Immunology. 28: 631-4. PMID 18792766 DOI: 10.1007/s10875-008-9245-9  0.301
2008 Wang L, Wildt KF, Zhu J, Zhang X, Feigenbaum L, Tessarollo L, Paul WE, Fowlkes BJ, Bosselut R. Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells Nature Immunology. 9: 1122-1130. PMID 18776904 DOI: 10.1038/Ni.1647  0.322
2008 Guo L, Urban JF, Zhu J, Paul WE. Elevating calcium in Th2 cells activates multiple pathways to induce IL-4 transcription and mRNA stabilization. Journal of Immunology (Baltimore, Md. : 1950). 181: 3984-93. PMID 18768853 DOI: 10.4049/Jimmunol.181.6.3984  0.363
2008 Zhu J, Paul WE. CD4 T cells: fates, functions, and faults. Blood. 112: 1557-69. PMID 18725574 DOI: 10.1182/Blood-2008-05-078154  0.42
2008 van Panhuys N, Tang SC, Prout M, Camberis M, Scarlett D, Roberts J, Hu-Li J, Paul WE, Le Gros G. In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 105: 12423-8. PMID 18719110 DOI: 10.1073/pnas.0806372105  0.3
2008 Le Gros G, Ben-Sasson SZ, Seder R, Finkelman FD, Paul WE. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 2943-51. PMID 18713964 DOI: 10.1084/Jem.172.3.921  0.432
2008 Chandele A, Joshi NS, Zhu J, Paul WE, Leonard WJ, Kaech SM. Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1. Journal of Immunology (Baltimore, Md. : 1950). 180: 5309-19. PMID 18390712 DOI: 10.4049/Jimmunol.180.8.5309  0.314
2008 Milner JD, Brenchley JM, Laurence A, Freeman AF, Hill BJ, Elias KM, Kanno Y, Spalding C, Elloumi HZ, Paulson ML, Davis J, Hsu A, Asher AI, O'Shea J, Holland SM, ... Paul WE, et al. Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature. 452: 773-6. PMID 18337720 DOI: 10.1038/nature06764  0.363
2008 Min B, Paul WE. Basophils and type 2 immunity Current Opinion in Hematology. 15: 59-63. PMID 18043247 DOI: 10.1097/Moh.0B013E3282F13Ce8  0.429
2008 Grimes HL, Velu CS, Horman S, Chaubey A, Bourdeau T, Xu H, Zhu J, Paul W, Colmenares C, Williams DA, Gebelein B. Gfi1 as a Regulator of Hematopoietic Differentiation. Blood. 112: sci-16-sci-16. DOI: 10.1182/Blood.V112.11.Sci-16.Sci-16  0.323
2008 Milner J, Paul W. OR.8. Lack of High Affinity Competition During Antigen-specific Priming of Polyclonal T Cells Unmasks IL-4 Production Clinical Immunology. 127: S6-S7. DOI: 10.1016/j.clim.2008.03.013  0.358
2007 Cohn M, Mitchison NA, Paul WE, Silverstein AM, Talmage DW, Weigert M. Reflections on the clonal-selection theory. Nature Reviews. Immunology. 7: 823-30. PMID 17893695 DOI: 10.1038/Nri2177  0.341
2007 Paul WE. Dendritic cells bask in the limelight. Cell. 130: 967-70. PMID 17889637 DOI: 10.1016/j.cell.2007.09.001  0.323
2007 Milner J, Ward J, Keane-Myers A, Min B, Paul WE. Repertoire-dependent immunopathology. Journal of Autoimmunity. 29: 257-61. PMID 17889507 DOI: 10.1016/J.Jaut.2007.07.019  0.347
2007 Milner JD, Ward JM, Keane-Myers A, Paul WE. Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 576-81. PMID 17202252 DOI: 10.1073/pnas.0610289104  0.332
2006 Zhu J, Jankovic D, Grinberg A, Guo L, Paul WE. Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion. Proceedings of the National Academy of Sciences of the United States of America. 103: 18214-9. PMID 17116877 DOI: 10.1073/pnas.0608981103  0.333
2006 Zhu J, Yamane H, Cote-Sierra J, Guo L, Paul WE. GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors. Cell Research. 16: 3-10. PMID 16467870 DOI: 10.1038/Sj.Cr.7310002  0.425
2006 Paul WE, Yamane H, Guo L, Zhu J. Transcriptional regulation of Th2 differentiation Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S99  0.429
2005 Guo L, Hu-Li J, Paul WE. Probabilistic regulation of IL-4 production. Journal of Clinical Immunology. 25: 573-81. PMID 16380820 DOI: 10.1007/S10875-005-8218-5  0.365
2005 Yamane H, Zhu J, Paul WE. Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment. The Journal of Experimental Medicine. 202: 793-804. PMID 16172258 DOI: 10.1084/Jem.20051304  0.421
2005 Guo L, Hu-Li J, Paul WE. Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13. Immunity. 23: 89-99. PMID 16039582 DOI: 10.1016/J.Immuni.2005.05.008  0.342
2005 Yamaoka K, Min B, Zhou YJ, Paul WE, O'shea JJ. Jak3 negatively regulates dendritic-cell cytokine production and survival. Blood. 106: 3227-33. PMID 16020505 DOI: 10.1182/Blood-2005-02-0769  0.415
2005 Min B, Yamane H, Hu-Li J, Paul WE. Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 174: 6039-44. PMID 15879097 DOI: 10.4049/Jimmunol.174.10.6039  0.462
2005 Rochman I, Paul WE, Ben-Sasson SZ. IL-6 increases primed cell expansion and survival. Journal of Immunology (Baltimore, Md. : 1950). 174: 4761-7. PMID 15814701  0.364
2004 Zhu J, Min B, Hu-Li J, Watson CJ, Grinberg A, Wang Q, Killeen N, Urban JF, Guo L, Paul WE. Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nature Immunology. 5: 1157-65. PMID 15475959 DOI: 10.1038/Ni1128  0.405
2004 Bocek P, Foucras G, Paul WE. Interferon gamma enhances both in vitro and in vivo priming of CD4+ T cells for IL-4 production. The Journal of Experimental Medicine. 199: 1619-30. PMID 15210741 DOI: 10.1084/jem.20032014  0.341
2004 Grossman Z, Min B, Meier-Schellersheim M, Paul WE. Concomitant regulation of T-cell activation and homeostasis. Nature Reviews. Immunology. 4: 387-95. PMID 15122204 DOI: 10.1038/Nri1355  0.396
2004 Cote-Sierra J, Foucras G, Guo L, Chiodetti L, Young HA, Hu-Li J, Zhu J, Paul WE. Interleukin 2 plays a central role in Th2 differentiation. Proceedings of the National Academy of Sciences of the United States of America. 101: 3880-5. PMID 15004274 DOI: 10.1073/pnas.0400339101  0.304
2004 Min B, Foucras G, Meier-Schellersheim M, Paul WE. Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire. Proceedings of the National Academy of Sciences of the United States of America. 101: 3874-9. PMID 15001705 DOI: 10.1073/Pnas.0400606101  0.323
2004 Guo L, Hu-Li J, Paul WE. Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus. Immunity. 20: 193-203. PMID 14975241 DOI: 10.1016/S1074-7613(04)00025-1  0.386
2003 Terabe M, Matsui S, Park JM, Mamura M, Noben-Trauth N, Donaldson DD, Chen W, Wahl SM, Ledbetter S, Pratt B, Letterio JJ, Paul WE, Berzofsky JA. Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. The Journal of Experimental Medicine. 198: 1741-52. PMID 14657224 DOI: 10.1084/jem.20022227  0.304
2003 Zhu J, Cote-Sierra J, Guo L, Paul WE. Stat5 activation plays a critical role in Th2 differentiation. Immunity. 19: 739-48. PMID 14614860 DOI: 10.1016/S1074-7613(03)00292-9  0.4
2003 Chong HJ, Andrew Bouton L, Bailey DP, Wright H, Ramirez C, Gharse A, Oskeritzian C, Xia HZ, Zhu J, Paul WE, Kepley C, Schwartz LB, Ryan JJ. IL-4 selectively enhances FcgammaRIII expression and signaling on mouse mast cells. Cellular Immunology. 224: 65-73. PMID 14609572 DOI: 10.1016/J.Cellimm.2003.08.004  0.403
2003 Noben-Trauth N, Lira R, Nagase H, Paul WE, Sacks DL. The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 170: 5152-8. PMID 12734362 DOI: 10.4049/Jimmunol.170.10.5152  0.343
2003 Yoshimoto T, Min B, Sugimoto T, Hayashi N, Ishikawa Y, Sasaki Y, Hata H, Takeda K, Okumura K, Van Kaer L, Paul WE, Nakanishi K. Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice. The Journal of Experimental Medicine. 197: 997-1005. PMID 12695491 DOI: 10.1084/Jem.20021701  0.452
2003 Min B, McHugh R, Sempowski GD, Mackall C, Foucras G, Paul WE. Neonates support lymphopenia-induced proliferation. Immunity. 18: 131-40. PMID 12530982 DOI: 10.1016/S1074-7613(02)00508-3  0.414
2003 Paul WE, Fathman CG, Glimcher LH. Annual review of immunology, vol. 20, 2002 Revista Do Instituto De Medicina Tropical De SãO Paulo. 45: 57-58. DOI: 10.1590/S0036-46652003000100018  0.351
2002 Zhu J, Guo L, Min B, Watson CJ, Hu-Li J, Young HA, Tsichlis PN, Paul WE. Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation. Immunity. 16: 733-44. PMID 12049724 DOI: 10.1016/S1074-7613(02)00317-5  0.397
2002 Noben-Trauth N, Hu-Li J, Paul WE. IL-4 secreted from individual naive CD4+ T cells acts in an autocrine manner to induce Th2 differentiation. European Journal of Immunology. 32: 1428-33. PMID 11981831 DOI: 10.1002/1521-4141(200205)32:5<1428::AID-IMMU1428>3.0.CO;2-0  0.354
2002 Hayashi N, Liu D, Min B, Ben-Sasson SZ, Paul WE. Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 6187-91. PMID 11959916 DOI: 10.1073/Pnas.092129899  0.362
2002 Grossman Z, Meier-Schellersheim M, Sousa AE, Victorino RMM, Paul WE. CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause? Nature Medicine. 8: 319-323. PMID 11927927 DOI: 10.1038/Nm0402-319  0.351
2002 Kodera T, McGaha TL, Phelps R, Paul WE, Bona CA. Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 3800-5. PMID 11891315 DOI: 10.1073/Pnas.052709999  0.313
2002 Min B, Sempowski GD, Paul WE. Neonates Support “Homeostatic” Proliferation Advances in Experimental Medicine and Biology. 512: 91-95. DOI: 10.1007/978-1-4615-0757-4_12  0.401
2001 Lighvani AA, Frucht DM, Jankovic D, Yamane H, Aliberti J, Hissong BD, Nguyen BV, Gadina M, Sher A, Paul WE, O'Shea JJ. T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 15137-42. PMID 11752460 DOI: 10.1073/Pnas.261570598  0.308
2001 Zhang Y, Apilado R, Coleman J, Ben-Sasson S, Tsang S, Hu-Li J, Paul WE, Huang H. Interferon gamma stabilizes the T helper cell type 1 phenotype. The Journal of Experimental Medicine. 194: 165-72. PMID 11457891 DOI: 10.1084/Jem.194.2.165  0.414
2001 Zhu J, Guo L, Watson CJ, Hu-Li J, Paul WE. Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion. Journal of Immunology (Baltimore, Md. : 1950). 166: 7276-81. PMID 11390477 DOI: 10.4049/Jimmunol.166.12.7276  0.447
2001 Hu-Li J, Pannetier C, Guo L, Löhning M, Gu H, Watson C, Assenmacher M, Radbruch A, Paul WE. Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity. 14: 1-11. PMID 11163225 DOI: 10.1016/S1074-7613(01)00084-X  0.391
2001 Ben-Sasson SZ, Gerstel R, Hu-Li J, Paul WE. Cell division is not a "clock" measuring acquisition of competence to produce IFN-gamma or IL-4. Journal of Immunology (Baltimore, Md. : 1950). 166: 112-20. PMID 11123283 DOI: 10.4049/jimmunol.166.1.112  0.33
2000 Yoshimoto T, Mizutani H, Tsutsui H, Noben-Trauth N, Yamanaka K, Tanaka M, Izumi S, Okamura H, Paul WE, Nakanishi K. IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6. Nature Immunology. 1: 132-7. PMID 11248805 DOI: 10.1038/77811  0.419
2000 Terabe M, Matsui S, Noben-Trauth N, Chen H, Watson C, Donaldson DD, Carbone DP, Paul WE, Berzofsky JA. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nature Immunology. 1: 515-20. PMID 11101874 DOI: 10.1038/82771  0.375
2000 Zhu J, Huang H, Guo L, Stonehouse T, Watson CJ, Hu-Li J, Paul WE. Transient inhibition of interleukin 4 signaling by T cell receptor ligation. The Journal of Experimental Medicine. 192: 1125-34. PMID 11034602 DOI: 10.1084/Jem.192.8.1125  0.399
2000 Noben-Trauth N, Hu-Li J, Paul WE. Conventional, naive CD4+ T cells provide an initial source of IL-4 during Th2 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 165: 3620-5. PMID 11034364 DOI: 10.4049/jimmunol.165.7.3620  0.311
2000 Grossman Z, Paul WE. Self-tolerance: Context dependent tuning of T cell antigen recognition Seminars in Immunology. 12: 197-203. PMID 10910740 DOI: 10.1006/Smim.2000.0232  0.304
2000 Ben-Sasson SZ, Makedonski K, Hu-Li J, Paul WE. Survival and cytokine polarization of naive CD4(+) T cells in vitro is largely dependent on exogenous cytokines. European Journal of Immunology. 30: 1308-17. PMID 10820376 DOI: 10.1002/(Sici)1521-4141(200005)30:5<1308::Aid-Immu1308>3.0.Co;2-I  0.427
2000 Jankovic D, Kullberg MC, Noben-Trauth N, Caspar P, Paul WE, Sher A. Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile. Journal of Immunology (Baltimore, Md. : 1950). 164: 3047-55. PMID 10706693 DOI: 10.4049/Jimmunol.164.6.3047  0.396
2000 Huang H, Paul WE. Protein tyrosine phosphatase activity is required for IL-4 induction of IL-4 receptor alpha-chain. Journal of Immunology (Baltimore, Md. : 1950). 164: 1211-5. PMID 10640732 DOI: 10.4049/Jimmunol.164.3.1211  0.347
1999 Pannetier C, Hu-Li J, Paul WE. Bias in the expression of IL-4 alleles: the use of T cells from a GFP knock-in mouse. Cold Spring Harbor Symposia On Quantitative Biology. 64: 599-602. PMID 11232337  0.304
1998 Nelms K, Huang H, Ryan J, Keegan A, Paul WE. Interleukin-4 receptor signalling mechanisms and their biological significance. Advances in Experimental Medicine and Biology. 452: 37-43. PMID 9889957 DOI: 10.1007/978-1-4615-5355-7_5  0.331
1998 Dent AL, Hu-Li J, Paul WE, Staudt LM. T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6. Proceedings of the National Academy of Sciences of the United States of America. 95: 13823-8. PMID 9811885 DOI: 10.1073/Pnas.95.23.13823  0.435
1998 Chen H, Paul WE. A population of CD62Llow Nk1.1- CD4+ T cells that resembles NK1.1+ CD4+ T cells. European Journal of Immunology. 28: 3172-82. PMID 9808186 DOI: 10.1002/(SICI)1521-4141(199810)28:10<3172::AID-IMMU3172>3.0.CO;2-I  0.301
1998 Chu CC, Paul WE. Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis Molecular Immunology. 35: 487-502. PMID 9798653 DOI: 10.1016/S0161-5890(98)00031-5  0.424
1998 Huang H, Pannetier C, Hu-Li J, Paul WE. Transient transfection of primary T helper cells by particle-mediated gene transfer. Journal of Immunological Methods. 215: 173-7. PMID 9744759 DOI: 10.1016/S0022-1759(98)00088-X  0.467
1998 Nelms K, Snow AL, Hu-Li J, Paul WE. FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation. Immunity. 9: 13-24. PMID 9697832 DOI: 10.1016/S1074-7613(00)80584-1  0.32
1998 Huang H, Paul WE. Impaired interleukin 4 signaling in T helper type 1 cells. The Journal of Experimental Medicine. 187: 1305-13. PMID 9547341 DOI: 10.1084/Jem.187.8.1305  0.41
1997 Noben-Trauth N, Shultz LD, Brombacher F, Urban JF, Gu H, Paul WE. An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 10838-43. PMID 9380721 DOI: 10.1073/pnas.94.20.10838  0.311
1997 Chu CC, Paul WE. Fig1, an interleukin 4-induced mouse B cell gene isolated by cDNA representational difference analysis Proceedings of the National Academy of Sciences of the United States of America. 94: 2507-2512. PMID 9122225 DOI: 10.1073/pnas.94.6.2507  0.341
1997 Paul WE. Interleukin 4: signalling mechanisms and control of T cell differentiation. Ciba Foundation Symposium. 204: 208-16; discussion 2. PMID 9107423 DOI: 10.1002/9780470515280.CH14  0.33
1997 Hu-Li J, Huang H, Ryan J, Paul WE. In differentiated CD4+ T cells, interleukin 4 production is cytokine-autonomous, whereas interferon gamma production is cytokine-dependent. Proceedings of the National Academy of Sciences of the United States of America. 94: 3189-94. PMID 9096368 DOI: 10.1073/PNAS.94.7.3189  0.319
1996 Oakes SA, Candotti F, Johnston JA, Chen YQ, Ryan JJ, Taylor N, Liu X, Hennighausen L, Notarangelo LD, Paul WE, Blaese RM, O'Shea JJ. Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways. Immunity. 5: 605-15. PMID 8986719 DOI: 10.1016/S1074-7613(00)80274-5  0.345
1996 Ryan JJ, McReynolds LJ, Keegan A, Wang LH, Garfein E, Rothman P, Nelms K, Paul WE. Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor Immunity. 4: 123-132. PMID 8624803 DOI: 10.1016/S1074-7613(00)80677-9  0.361
1996 Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC, Grosveld G, Paul WE, Ihle JN. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature. 380: 630-3. PMID 8602264 DOI: 10.1038/380630A0  0.453
1995 Yoshimoto T, Bendelac A, Watson C, Hu-Li J, Paul WE. Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production. Science (New York, N.Y.). 270: 1845-7. PMID 8525383 DOI: 10.1126/Science.270.5243.1845  0.743
1995 Yoshimoto T, Bendelac A, Hu-Li J, Paul WE. Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4. Proceedings of the National Academy of Sciences of the United States of America. 92: 11931-4. PMID 8524877 DOI: 10.1073/Pnas.92.25.11931  0.736
1995 Nakanishi K, Yoshimoto T, Chu CC, Matsumoto H, Hase K, Nagai N, Tanaka T, Miyasaka M, Paul WE, Shinka S. IL-2 inhibits IL-4-dependent IgE and IgG1 production in vitro and in vivo. International Immunology. 7: 259-68. PMID 7734421 DOI: 10.1093/INTIMM/7.2.259  0.322
1995 Aoki I, Kinzer C, Shirai A, Paul WE, Klinman DM. IgE receptor-positive non-B/non-T cells dominate the production of interleukin 4 and interleukin 6 in immunized mice Proceedings of the National Academy of Sciences of the United States of America. 92: 2534-2538. PMID 7708680 DOI: 10.1073/pnas.92.7.2534  0.429
1995 Kinzer CA, Keegan AD, Paul WE. Identification of Fc epsilon RIneg mast cells in mouse bone marrow cell cultures. Use of a monoclonal anti-p161 antibody. The Journal of Experimental Medicine. 182: 575-9. PMID 7629514 DOI: 10.1084/jem.182.2.575  0.348
1995 Ryan JJ, Kinzer CA, Paul WE. Mast cells lacking the high affinity immunoglobulin E receptor are deficient in Fc epsilon RI gamma messenger RNA. The Journal of Experimental Medicine. 182: 567-74. PMID 7629513 DOI: 10.1084/Jem.182.2.567  0.407
1995 Pernis A, Witthuhn B, Keegan AD, Nelms K, Garfein E, Ihle JN, Paul WE, Pierce JH, Rothman P. Interleukin 4 signals through two related pathways. Proceedings of the National Academy of Sciences of the United States of America. 92: 7971-5. PMID 7544011 DOI: 10.1073/Pnas.92.17.7971  0.353
1995 Keegan AD, Johnston JA, Tortolani PJ, Mcreynolds LJ, Kinzer C, O'Shea JJ, Paul WE. Similarities and differences in signal transduction by interleukin 4 and interleukin 13: Analysis of Janus kinase activation Proceedings of the National Academy of Sciences of the United States of America. 92: 7681-7685. PMID 7544000 DOI: 10.1073/Pnas.92.17.7681  0.361
1994 Seder RA, Germain RN, Linsley PS, Paul WE. CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production. The Journal of Experimental Medicine. 179: 299-304. PMID 8270872 DOI: 10.1084/Jem.179.1.299  0.343
1994 Seder RA, Paul WE. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annual Review of Immunology. 12: 635-73. PMID 7912089 DOI: 10.1146/annurev.iy.12.040194.003223  0.313
1994 Yoshimoto T, Paul WE. CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. The Journal of Experimental Medicine. 179: 1285-95. PMID 7908323 DOI: 10.1084/Jem.179.4.1285  0.473
1993 Tanaka T, Hu-Li J, Seder RA, Fazekas de St Groth B, Paul WE. Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement. Proceedings of the National Academy of Sciences of the United States of America. 90: 5914-8. PMID 8100998 DOI: 10.1073/Pnas.90.13.5914  0.481
1993 Seder RA, Gazzinelli R, Sher A, Paul WE. Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proceedings of the National Academy of Sciences of the United States of America. 90: 10188-92. PMID 7901851 DOI: 10.1073/Pnas.90.21.10188  0.332
1992 Bendelac A, Matzinger P, Seder RA, Paul WE, Schwartz RH. Activation events during thymic selection. The Journal of Experimental Medicine. 175: 731-42. PMID 1740662 DOI: 10.1084/Jem.175.3.731  0.714
1992 Tanaka T, Chu CC, Paul WE. An antisense oligonucleotide complementary to a sequence in I gamma 2b increases gamma 2b germline transcripts, stimulates B cell DNA synthesis, and inhibits immunoglobulin secretion. The Journal of Experimental Medicine. 175: 597-607. PMID 1732418 DOI: 10.1084/Jem.175.2.597  0.34
1992 Tsang WK, Mizuguchi J, Ishida Y, Watson C, Chused T, Inman J, Margulies DH, Paul WE. Failure of signaling through a chimeric class I-immunoglobulin molecule expressed on the surface of transfected B lymphoma cells and cells of transgenic mice. Cellular Immunology. 143: 80-96. PMID 1623567 DOI: 10.1016/0008-8749(92)90007-C  0.422
1992 Paul WE, Kishimoto T, Melchers F, Metcalf D, Mosmann T, Oppenheim J, Ruddle N, Van Snick J. Nomenclature for secreted regulatory proteins of the immune system (interleukins). WHO-IUIS Nomenclature Subcommittee on Interleukin Designation. Clinical and Experimental Immunology. 88: 367. PMID 1572103 DOI: 10.1111/J.1365-2249.1992.Tb03089.X  0.3
1992 Seder RA, Paul WE, Davis MM, Fazekas de St Groth B. The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. The Journal of Experimental Medicine. 176: 1091-8. PMID 1328464 DOI: 10.1084/Jem.176.4.1091  0.462
1991 Seder RA, Paul WE, Ben-Sasson SZ, LeGros GS, Kagey-Sobotka A, Finkelman FD, Pierce JH, Plaut M. Production of interleukin-4 and other cytokines following stimulation of mast cell lines and in vivo mast cells/basophils. International Archives of Allergy and Applied Immunology. 94: 137-40. PMID 1834578 DOI: 10.1159/000235345  0.329
1991 Seder RA, Le Gros G, Ben-Sasson SZ, Urban J, Finkelman FD, Paul WE. Increased frequency of interleukin 4-producing T cells as a result of polyclonal priming. Use of a single-cell assay to detect interleukin 4-producing cells. European Journal of Immunology. 21: 1241-7. PMID 1828031 DOI: 10.1002/Eji.1830210522  0.447
1991 Seder RA, Paul WE, Dvorak AM, Sharkis SJ, Kagey-Sobotka A, Niv Y, Finkelman FD, Barbieri SA, Galli SJ, Plaut M. Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils. Proceedings of the National Academy of Sciences of the United States of America. 88: 2835-9. PMID 1826367 DOI: 10.1073/Pnas.88.7.2835  0.402
1990 Conrad DH, Ben-Sasson SZ, Le Gros G, Finkelman FD, Paul WE. Infection with Nippostrongylus brasiliensis or injection of anti-IgD antibodies markedly enhances Fc-receptor-mediated interleukin 4 production by non-B, non-T cells. The Journal of Experimental Medicine. 171: 1497-508. PMID 2332730 DOI: 10.1084/JEM.171.5.1497  0.398
1990 Ben-Sasson SZ, Le Gros G, Conrad DH, Finkelman FD, Paul WE. Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines. Proceedings of the National Academy of Sciences of the United States of America. 87: 1421-5. PMID 2106135 DOI: 10.1073/Pnas.87.4.1421  0.475
1990 Paul WE. B-cell activation and the one B cell/one antibody paradigm. Immunological Reviews. 115: 197-204; discussion . PMID 1697279 DOI: 10.1111/j.1600-065X.1990.tb00790.x  0.322
1990 Finkelman FD, Holmes J, Katona IM, Urban JF, Beckmann MP, Park LS, Schooley KA, Coffman RL, Mosmann TR, Paul WE. Lymphokine control of in vivo immunoglobulin isotype selection. Annual Review of Immunology. 8: 303-33. PMID 1693082 DOI: 10.1146/annurev.iy.08.040190.001511  0.348
1989 Hornbeck P, Nakabayashi H, Fowlkes BJ, Paul WE, Kligman D. A major myristylated substrate of protein kinase C and protein kinase C itself are differentially regulated during murine B- and T-lymphocyte development and activation Molecular and Cellular Biology. 9: 3727-3735. PMID 2789336 DOI: 10.1128/Mcb.9.9.3727  0.43
1989 Snapper CM, Hooley JJ, Atasoy U, Finkelman FD, Paul WE. Differential regulation of murine B cell FcγRII expression by CD4+ T helper subsets Journal of Immunology. 143: 2133-2141. PMID 2528589  0.38
1989 Keegan AD, Snapper CM, Van Dusen R, Paul WE, Conrad DH. Superinduction of the murine B cell Fc epsilon RII by T helper cell clones. Role of IL-4. Journal of Immunology (Baltimore, Md. : 1950). 142: 3868-74. PMID 2523937  0.367
1989 Hauser C, Snapper CM, Ohara J, Paul WE, Katz SI. T helper cells grown with hapten-modified cultured Langerhans' cells produce interleukin 4 and stimulate IgE production by B cells. European Journal of Immunology. 19: 245-51. PMID 2522879 DOI: 10.1002/eji.1830190205  0.38
1989 Finkelman FD, Holmes J, Urban JF, Paul WE, Katona IM. T help requirements for the generation of an in vivo IgE response: a late acting form of T cell help other than IL-4 is required for IgE but not for IgG1 production. Journal of Immunology (Baltimore, Md. : 1950). 142: 403-8. PMID 2521345  0.362
1989 Finkelman FD, Katona IM, Urban JF, Paul WE. Control of in vivo IgE production in the mouse by interleukin 4. Ciba Foundation Symposium. 147: 3-17; discussion 17-. PMID 2515949 DOI: 10.1002/9780470513866.ch2  0.323
1989 Paul WE. Pleiotropy and redundancy: T cell-derived lymphokines in the immune response. Cell. 57: 521-4. PMID 2497989 DOI: 10.1016/0092-8674(89)90121-9  0.31
1989 Plaut M, Pierce JH, Watson CJ, Hanley-Hyde J, Nordan RP, Paul WE. Mast cell lines produce lymphokines in response to cross-linkage of Fc epsilon RI or to calcium ionophores. Nature. 339: 64-7. PMID 2469965 DOI: 10.1038/339064A0  0.31
1989 Peschel C, Green I, Paul W. Interleukin-4 induces a substance in bone marrow stromal cells that reversibly inhibits factor-dependent and factor-independent cell proliferation Blood. 73: 1130-1141. DOI: 10.1182/Blood.V73.5.1130.1130  0.407
1988 Paul WE. Interleukin 4/B cell stimulatory factor 1: one lymphokine, many functions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 1: 456-61. PMID 3315808 DOI: 10.1096/fasebj.1.6.3315808  0.379
1988 Snapper CM, Finkelman FD, Paul WE. Regulation of IgG1 and IgE production by interleukin 4. Immunological Reviews. 102: 51-75. PMID 3284816 DOI: 10.1111/J.1600-065X.1988.Tb00741.X  0.308
1988 Ohara J, Paul WE. Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression. Proceedings of the National Academy of Sciences of the United States of America. 85: 8221-5. PMID 3263648 DOI: 10.1073/pnas.85.21.8221  0.305
1988 Snapper CM, Finkelman FD, Paul WE. Differential regulation of IgG1 and IgE synthesis by interleukin 4. The Journal of Experimental Medicine. 167: 183-96. PMID 3257252 DOI: 10.1084/Jem.167.1.183  0.427
1988 Polla BS, Ohara J, Paul WE, Nabavi N, Myer A, Liou HC, Shen FW, Gillis S, Bonventre JV, Glimcher LH. Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens Journal of Molecular and Cellular Immunology. 3: 363-373. PMID 3151065  0.321
1988 Snapper CM, Hornbeck PV, Atasoy U, Pereira GM, Paul WE. Interleukin 4 induces membrane Thy-1 expression on normal murine B cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 6107-11. PMID 2901096 DOI: 10.1073/Pnas.85.16.6107  0.504
1987 Siegel JN, Turner CA, Klinman DM, Wilkinson M, Steinberg AD, MacLeod CL, Paul WE, Davis MM, Cohen DI. Sequence analysis and expression of an X-linked, lymphocyte-regulated gene family (XLR). The Journal of Experimental Medicine. 166: 1702-15. PMID 3681192 DOI: 10.1084/Jem.166.6.1702  0.32
1987 Paul WE, Mizuguchi J, Beaven MA, Hornbeck P, Tsang W, Ohara J. B lymphocyte activation. The roles of receptor cross-linkage and BSF-1. Advances in Experimental Medicine and Biology. 213: 207-14. PMID 3498299 DOI: 10.1007/978-1-4684-5323-2_20  0.48
1987 Brown MA, Pierce JH, Watson CJ, Falco J, Ihle JN, Paul WE. B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells. Cell. 50: 809-18. PMID 3497723 DOI: 10.1016/0092-8674(87)90339-4  0.307
1987 Snapper CM, Paul WE. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science (New York, N.Y.). 236: 944-7. PMID 3107127 DOI: 10.1126/science.3107127  0.365
1987 Ohara J, Paul WE. Receptors for B-cell stimulatory factor-1 expressed on cells of haematopoietic lineage. Nature. 325: 537-40. PMID 3100961 DOI: 10.1038/325537a0  0.407
1987 Hu-Li J, Shevach EM, Mizuguchi J, Ohara J, Mosmann T, Paul WE. B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes. The Journal of Experimental Medicine. 165: 157-72. PMID 3098893 DOI: 10.1084/Jem.165.1.157  0.446
1987 Lichtman AH, Williams ME, Ohara J, Paul WE, Faller DV, Abbas AK. Retrovirus infection alters growth factor responses of T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 138: 3276-83. PMID 3033071  0.331
1987 Kurt-Jones EA, Hamberg S, Ohara J, Paul WE, Abbas AK. Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness. The Journal of Experimental Medicine. 166: 1774-87. PMID 2960773 DOI: 10.1084/Jem.166.6.1774  0.345
1987 Paul WE, Brown M, Hornbeck P, Mizuguchi J, Ohara J, Rabin E, Snapper C, Tsang W. Regulation of B-lymphocyte activation, proliferation, and differentiation. Annals of the New York Academy of Sciences. 505: 82-9. PMID 2825578 DOI: 10.1111/J.1749-6632.1987.Tb51284.X  0.33
1987 Peschel C, Paul W, Ohara J, Green I. Effects of B cell stimulatory factor-1/interleukin 4 on hematopoietic progenitor cells Blood. 70: 254-263. DOI: 10.1182/Blood.V70.1.254.Bloodjournal701254  0.471
1986 Finkelman FD, Katona IM, Urban JF, Snapper CM, Ohara J, Paul WE. Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1. Proceedings of the National Academy of Sciences of the United States of America. 83: 9675-8. PMID 3491987 DOI: 10.1073/Pnas.83.24.9675  0.446
1986 Polla BS, Poljak A, Geier SG, Nathenson SG, Ohara J, Paul WE, Glimcher LH. Three distinct signals can induce class II gene expression in a murine pre-B-cell line. Proceedings of the National Academy of Sciences of the United States of America. 83: 4878-82. PMID 3487783 DOI: 10.1073/Pnas.83.13.4878  0.488
1986 Rabin EM, Mond JJ, Ohara J, Paul WE. B cell stimulatory factor 1 (BSF-1) prepares resting B cells to enter S phase in response to anti-IgM and lipopolysaccharide. The Journal of Experimental Medicine. 164: 517-31. PMID 3487616 DOI: 10.1084/Jem.164.2.517  0.431
1986 Coffman RL, Ohara J, Bond MW, Carty J, Zlotnik A, Paul WE. B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. Journal of Immunology (Baltimore, Md. : 1950). 136: 4538-41. PMID 3486902  0.375
1986 Polla BS, Poljak A, Ohara J, Paul WE, Glimcher LH. Regulation of class II gene expression: Analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines Journal of Immunology. 137: 3332-3337. PMID 3095428  0.479
1986 Paul WE, Mizuguchi J, Brown M, Nakanishi K, Hornbeck P, Rabin E, Ohara J. Regulation of B-lymphocyte activation, proliferation, and immunoglobulin secretion. Cellular Immunology. 99: 7-13. PMID 3093104 DOI: 10.1016/0008-8749(86)90209-1  0.461
1986 Mosmann TR, Bond MW, Coffman RL, Ohara J, Paul WE. T-cell and mast cell lines respond to B-cell stimulatory factor 1 Proceedings of the National Academy of Sciences of the United States of America. 83: 5654-5658. PMID 3090545 DOI: 10.1073/Pnas.83.15.5654  0.378
1986 Mizuguchi J, Beaven MA, Li JH, Paul WE. Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 4474-8. PMID 3086884 DOI: 10.1073/Pnas.83.12.4474  0.415
1986 Chatterjee-Das S, Schlauder GG, Sachs DH, Glimcher LH, Paul WE, McKean DJ. A biochemical analysis of Ak molecules from mutant antigen presenting cell lines. Immunogenetics. 23: 121-5. PMID 3082750 DOI: 10.1007/Bf00377972  0.54
1985 Nakanishi K, Malek TR, Smith KA, Hamaoka T, Shevach EM, Paul WE. Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis. The Journal of Experimental Medicine. 160: 1605-21. PMID 6439814 DOI: 10.1084/Jem.160.6.1605  0.378
1985 Vitetta ES, Ohara J, Myers CD, Layton JE, Krammer PH, Paul WE. Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1. The Journal of Experimental Medicine. 162: 1726-31. PMID 3932582 DOI: 10.1084/Jem.162.5.1726  0.451
1985 Ashwell JD, DeFranco AL, Paul WE, Schwartz RH. Can resting B cells present antigen to T cells? Federation Proceedings. 44: 2475-2479. PMID 3886434  0.635
1985 Schlauder GG, Bell MP, paul WE, Glimcher LH, McKean DJ. Biochemical characterization of I-Ak proteins from mutant antigen-presenting B-cell-B-lymphoma hybridomas Molecular Immunology. 22: 597-607. PMID 3875018 DOI: 10.1016/0161-5890(85)90184-1  0.524
1985 Paul WE. Living with lymphocytes. International Archives of Allergy and Applied Immunology. 77: 7-12. PMID 3874170 DOI: 10.1159/000233745  0.33
1985 DeFranco AL, Raveche ES, Paul WE. Separate control of B lymphocyte early activation and proliferation in response to anti-IgM antibodies Journal of Immunology. 135: 87-94. PMID 3873499  0.552
1985 Rabin EM, Ohara J, Paul WE. B-cell stimulatory factor 1 activates resting B cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 2935-9. PMID 3873071 DOI: 10.1073/pnas.82.9.2935  0.355
1985 Cohen DI, Steinberg AD, Paul WE, Davis MM. Expression of an X-linked gene family (XLR) in late-stage B cells and its alteration by the xid mutation. Nature. 314: 372-4. PMID 3872416 DOI: 10.1038/314372A0  0.416
1985 Cohen DI, Hedrick SM, Nielsen EA, D'Eustachio P, Ruddle F, Steinberg AD, Paul WE, Davis MM. Isolation of a cDNA clone corresponding to an X-linked gene family (XLR) closely linked to the murine immunodeficiency disorder xid. Nature. 314: 369-72. PMID 2984575 DOI: 10.1038/314369A0  0.581
1985 Ohara J, Paul WE. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature. 315: 333-6. PMID 2582266 DOI: 10.1038/315333a0  0.393
1984 Ashwell JD, DeFranco AL, Paul WE, Schwartz RH. Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation Journal of Experimental Medicine. 159: 881-905. PMID 6607969 DOI: 10.1084/Jem.159.3.881  0.681
1984 Howard M, Matis L, Malek TR, Shevach E, Kell W, Cohen D, Nakanishi K, Paul WE. Interleukin 2 induces antigen-reactive T cell lines to secrete BCGF-I. The Journal of Experimental Medicine. 158: 2024-39. PMID 6606015 DOI: 10.1084/Jem.158.6.2024  0.409
1984 Nakanishi K, Cohen DI, Blackman M, Nielsen E, Ohara J, Hamaoka T, Koshland ME, Paul WE. Ig RNA expression in normal B cells stimulated with anti-IgM antibody and T cell-derived growth and differentiation factors. The Journal of Experimental Medicine. 160: 1736-51. PMID 6439815 DOI: 10.1084/Jem.160.6.1736  0.366
1984 Howard M, Nakanishi K, Paul WE. B cell growth and differentiation factors. Immunological Reviews. 78: 185-210. PMID 6429034 DOI: 10.1111/j.1600-065X.1984.tb00482.x  0.326
1984 Mongini PK, Longo DL, Paul WE. T cell regulation of immunoglobulin class expression in the B cell response to TNP-Ficoll: characterization of the T cell responsible for preferential enhancement of the IgG2a response. Journal of Immunology (Baltimore, Md. : 1950). 132: 1647-53. PMID 6230389  0.388
1984 DeFranco AL, Ashwell JD, Schwartz RH, Paul WE. Polyclonal stimulation of resting B lymphocytes by antigen-specific T lymphocytes Journal of Experimental Medicine. 159: 861-880. PMID 6199453 DOI: 10.1084/Jem.159.3.861  0.686
1983 Kung JT, Sharrow SO, Thomas CA, Paul WE. Analysis of B lymphocyte differentiation antigens by flow microfluorometry Immunological Reviews. 51-68. PMID 6984002 DOI: 10.1111/j.1600-065X.1983.tb00448.x  0.349
1983 Mongini PK, Paul WE, Metcalf ES. IgG subclass, IgE, and IgA anti-trinitrophenyl antibody production within trinitrophenyl-Ficoll-responsive B cell clones. Evidence in support of three distinct switching pathways. The Journal of Experimental Medicine. 157: 69-85. PMID 6600273  0.402
1983 Mond JJ, Norton G, Paul WE, Scher I, Finkelman FD, House S, Schaefer M, Mongini PK, Hansen C, Bona C. Establishment of an inbred line of mice that express a synergistic immune defect precluding in vitro responses to type 1 and type 2 antigens, B cell mitogens, and a number of T cell-derived helper factors. The Journal of Experimental Medicine. 158: 1401-14. PMID 6415204 DOI: 10.1084/Jem.158.5.1401  0.435
1983 Matis LA, Glimcher LH, Paul WE, Schwartz RH. Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules Proceedings of the National Academy of Sciences of the United States of America. 80: 6019-6023. PMID 6310611 DOI: 10.1073/Pnas.80.19.6019  0.558
1983 Glimcher LH, Kruisbeek AM, Paul WE, Green I. Functional activity of a transformed thymic epithelial cell line Scandinavian Journal of Immunology. 17: 1-11. PMID 6302828 DOI: 10.1111/J.1365-3083.1983.Tb00759.X  0.575
1983 Glimcher LH, Hamano T, Asofsky R, Sachs DH, Pierres M, Samelson LE, Sharrow SO, Paul WE. IA mutant functional antigen-presenting cell lines. Journal of Immunology (Baltimore, Md. : 1950). 130: 2287-94. PMID 6300242  0.383
1983 Howard M, Paul WE. Regulation of B-cell growth and differentiation by soluble factors. Annual Review of Immunology. 1: 307-33. PMID 6242466 DOI: 10.1146/annurev.iy.01.040183.001515  0.32
1983 Glimcher LH, Sharrow SO, Paul WE. Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules Journal of Experimental Medicine. 158: 1573-1588. PMID 6195287 DOI: 10.1084/Jem.158.5.1573  0.572
1983 Goldberg B, Paul WE, Bona CA. Idiotype-antiidiotype regulation. IV. Expression of common regulatory idiotopes on fructosan-binding and non-fructosan-binding monoclonal immunoglobulin. The Journal of Experimental Medicine. 158: 515-28. PMID 6193225 DOI: 10.1084/Jem.158.2.515  0.321
1983 Stein KE, Zopf DA, Miller CB, Johnson BM, Mongini PK, Ahmed A, Paul WE. Immune response to a thymus-dependent form of B512 dextran requires the presence of Lyb-5+ lymphocytes. The Journal of Experimental Medicine. 157: 657-66. PMID 6185616 DOI: 10.1084/jem.157.2.657  0.356
1982 Howard M, Farrar J, Hilfiker M, Johnson B, Takatsu K, Hamaoka T, Paul WE. Identification of a T cell-derived b cell growth factor distinct from interleukin 2. The Journal of Experimental Medicine. 155: 914-23. PMID 6977612 DOI: 10.1084/jem.155.3.914  0.365
1982 Mongini PK, Paul WE, Metcalf ES. T cell regulation of immunoglobulin class expression in the antibody response to trinitrophenyl-ficoll. Evidence for T cell enhancement of the immunoglobulin class switch. The Journal of Experimental Medicine. 155: 884-902. PMID 6977611  0.417
1982 Sredni B, Sieckmann DG, Kumagai S, House S, Green I, Paul WE. Long-term culture and cloning of nontransformed human B lymphocytes. The Journal of Experimental Medicine. 154: 1500-16. PMID 6975349 DOI: 10.1084/Jem.154.5.1500  0.354
1982 DeFranco AL, Kung JT, Paul WE. Regulation of growth and proliferation in B cell subpopulations Immunological Reviews. 161-182. PMID 6806172 DOI: 10.1111/J.1600-065X.1982.Tb00423.X  0.647
1982 Defranco AL, Raveche ES, Asofsky R, Paul WE. Frequency of B lymphocytes responsive to anti-immunoglobulin Journal of Experimental Medicine. 155: 1523-1536. PMID 6802927 DOI: 10.1084/Jem.155.5.1523  0.67
1982 Mond JJ, Scher I, Cossman J, Kessler S, Mongini PK, Hansen C, Finkelman FD, Paul WE. Role of the thymus in directing the development of a subset of B lymphocytes. The Journal of Experimental Medicine. 155: 924-36. PMID 6801183 DOI: 10.1084/Jem.155.3.924  0.362
1982 Howard M, Kessler S, Chused T, Paul WE. Long-term culture of normal mouse B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 78: 5788-92. PMID 6795635 DOI: 10.1073/pnas.78.9.5788  0.34
1982 Glimcher LH, Kim KJ, Green I, Paul WE. Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells Journal of Experimental Medicine. 155: 445-459. PMID 6460073 DOI: 10.1084/Jem.155.2.445  0.562
1982 Glimcher LH, Hamano T, Asofsky R, Herber-Katz E, Hedrick S, Schwartz RH, Paul WE. I region-restricted antigen presentation by B cell-B lymphoma hybridomas. Nature. 298: 283-4. PMID 6211627 DOI: 10.1038/298283A0  0.736
1982 Mongini PK, Paul WE. T cell regulation of the IgG2a response to TNP-Ficoll: evidence that allotype congenic mice contain both helper cells that preferentially enhance IgG2a synthesis and suppressor cells that specifically suppress IgG2 synthesis. Journal of Immunology (Baltimore, Md. : 1950). 128: 2405-10. PMID 6210729  0.389
1982 Howard M, Nakanishi K, Farrar J, Paul W. Soluble factors required for B-cell proliferation Cellular Immunology. 70: 386. DOI: 10.1016/0008-8749(82)90358-6  0.372
1981 Paul WE, Sredni B, Schwartz RH. Long-term growth and cloning of non-transformed lymphocytes. Nature. 294: 697-9. PMID 6976514 DOI: 10.1038/294697A0  0.344
1981 Tse HY, Mond JJ, Paul WE. T lymphocyte-dependent B lymphocyte proliferative response to antigen. I. Genetic restriction of the stimulation of B lymphocyte proliferation Journal of Experimental Medicine. 153: 871-882. PMID 6972992  0.334
1981 Mongini PK, Stein KE, Paul WE. T cell regulation of IgG subclass antibody production in response to T-independent antigens. The Journal of Experimental Medicine. 153: 1-12. PMID 6969777 DOI: 10.1084/Jem.153.1.1  0.51
1981 Sredni B, Matis LA, Lerner EA, Paul WE, Schwartz RH. Antigen-specific T cell clones restricted to unique F1 major histocompatibility complex determinants. Inhibition of proliferation with monoclonal anti-Ia antibody. The Journal of Experimental Medicine. 153: 677-93. PMID 6166704 DOI: 10.1084/Jem.153.3.677  0.77
1980 Bona C, Mond JJ, Paul WE. Synergistic genetic defect in B-lymphocyte function. I. Defective responses to B-cell stimulants and their genetic basis. The Journal of Experimental Medicine. 151: 224-34. PMID 6965307 DOI: 10.1084/Jem.151.1.224  0.369
1980 Tse HY, Schwartz RH, Paul WE. Cell-cell interactions in the T cell proliferative response. I. Analysis of the cell types involved and evidence for nonspecific T cell recruitment Journal of Immunology. 125: 491-500. PMID 6771325  0.382
1979 Perlmutter RM, Nahm M, Stein KE, Slack J, Zitron I, Paul WE, Davie JM. Immunoglobulin subclass-specific immunodeficiency in mice with an X-linked B-lymphocyte defect. The Journal of Experimental Medicine. 149: 993-8. PMID 311819 DOI: 10.1084/Jem.149.4.993  0.428
1979 Schwartz RH, Yano A, Stimpfling JH, Paul WE. Gene complementation in the T-lymphocyte proliferative response to poly (Glu55Lys36Phe9)n. A demonstration that both immune response gene products must be expressed in the same antigen-presenting cell. The Journal of Experimental Medicine. 149: 40-57. PMID 105077 DOI: 10.1084/Jem.149.1.40  0.426
1979 Sieckmann DG, Scher I, Asofsky R, Mosier DE, Paul WE. Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset of B lymphocytes. The Journal of Experimental Medicine. 148: 1628-43. PMID 102729 DOI: 10.1084/Jem.148.6.1628  0.496
1979 Bona C, Hooghe R, Cazenave PA, Leguérn C, Paul WE. Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes. The Journal of Experimental Medicine. 149: 815-23. PMID 85684 DOI: 10.1084/jem.149.4.815  0.326
1979 Bona C, Paul WE. Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype. The Journal of Experimental Medicine. 149: 592-600. PMID 85681 DOI: 10.1084/jem.149.3.592  0.371
1979 Subbarao B, Mosier DE, Ahmed A, Mond JJ, Scher I, Paul WE. Role of a nonimmunoglobulin cell surface determinant in the activation of B lymphocytes by thymus-independent antigens. The Journal of Experimental Medicine. 149: 495-506. PMID 84046 DOI: 10.1084/Jem.149.2.495  0.478
1978 Sieckmann DG, Asofsky R, Mosier DE, Zitron IM, Paul WE. Activation of mouse lymphocytes by anti-immunoglobulin. I. Parameters of the proliferative response. The Journal of Experimental Medicine. 147: 814-29. PMID 416168 DOI: 10.1084/Jem.147.3.814  0.399
1978 Schwartz RH, Yano A, Paul WE. Interaction between antigen-presenting cells and primed T lymphocytes: an assessment of Ir gene expression in the antigen-presenting cell. Immunological Reviews. 40: 153-80. PMID 112037 DOI: 10.1111/j.1600-065x.1978.tb00405.x  0.336
1978 Mond JJ, Scher I, Mosier DE, Baese M, Paul WE. T-independent responses in B cell-defective CBA/N mice to Brucella abortus and to trinitrophenyl (TNP) conjugates of Brucella abortus. European Journal of Immunology. 8: 459-63. PMID 99320 DOI: 10.1002/Eji.1830080703  0.437
1978 Yano A, Schwartz RH, Paul WE. Antigen presentation in the murine T lymphocyte proliferative response. II. Ir-GAT-controlled T lymphocyte responses require antigen-presenting cells from a high responder donor. European Journal of Immunology. 8: 344-7. PMID 99319 DOI: 10.1002/Eji.1830080510  0.475
1978 Schwartz RH, David CS, Dorf ME, Benacerraf B, Paul WE. Inhibition of dual Ir gene-controlled T-lymphocyte proliferative response to poly (Glu56Lys35Phe9)n with anti-Ia antisera directed against products of either I-A or I-C subregion. Proceedings of the National Academy of Sciences of the United States of America. 75: 2387-91. PMID 97668 DOI: 10.1073/Pnas.75.5.2387  0.537
1978 Zitron IM, Mosier DE, Paul WE. The role of surface IgD in the response to thymic-independent antigens. The Journal of Experimental Medicine. 146: 1707-18. PMID 72781 DOI: 10.1084/jem.146.6.1707  0.385
1978 Paul WE, Scher I, Mond JJ, Ahmed AA, Subbarao B, Mosier DE. B lymphocyte development, heterogeneity, and function Arthritis & Rheumatism. 21: S174-S179. DOI: 10.1002/Art.1780210929  0.443
1977 Mosier DE, Zaldivar NM, Goldings E, Mond J, Scher I, Paul WE. Formation of antibody in the newborn mouse: study of T-cell-independent antibody response. The Journal of Infectious Diseases. S14-9. PMID 408430 DOI: 10.1093/infdis/136.Supplement.S14  0.378
1977 Paul WE, Benacerraf B. Functional specificity of thymus- dependent lymphocytes. Science (New York, N.Y.). 195: 1293-300. PMID 320663 DOI: 10.1126/Science.320663  0.502
1977 Mond JJ, Lieberman R, Inman JK, Mosier DE, Paul WE. Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers. The Journal of Experimental Medicine. 146: 1138-42. PMID 302313 DOI: 10.1084/Jem.146.4.1138  0.351
1977 Paul WE, Shevach EM, Pickeral S, Thomas DW, Rosenthal AS. Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells. The Journal of Experimental Medicine. 145: 618-30. PMID 233906 DOI: 10.1084/Jem.145.3.618  0.356
1977 Yano A, Schwartz RH, Paul WE. Antigen presentation in the murine T-lymphocyte proliferative response. I. Requirement for genetic identity at the major histocompatibility complex. The Journal of Experimental Medicine. 146: 828-43. PMID 70497 DOI: 10.1084/jem.146.3.828  0.383
1977 Schwartz RH, Horton CL, Paul WE. T-lymphocyte-enriched murine peritoneal exudate cells. IV. Genetic control of cross-stimulation at the T-cell level. The Journal of Experimental Medicine. 145: 327-43. PMID 64582 DOI: 10.1084/Jem.145.2.327  0.386
1976 Schwartz RH, David CS, Sachs DH, Paul WE. T lymphocyte-enriched murine peritoneal exudate cells. III. Inhibition of antigen-induced T lymphocyte Proliferation with anti-Ia antisera. Journal of Immunology (Baltimore, Md. : 1950). 117: 531-40. PMID 1084902  0.362
1976 Schwartz RH, Dorf ME, Benacerraf B, Paul WE. The requirement for two complementing Ir-GLphi immune response genes in the T-lymphocyte proliferative response to poly-(Glu53Lys36Phe11). The Journal of Experimental Medicine. 143: 897-905. PMID 1082919  0.461
1976 Schwartz RH, Paul WE. T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation. The Journal of Experimental Medicine. 143: 529-40. PMID 1082491 DOI: 10.1084/jem.143.3.529  0.38
1976 Scher I, Sharrow SO, Wistar R, Asofsky R, Paul WE. B-lymphocyte heterogeneity: ontogenetic development and organ distribution of B-lymphocyte populations defined by their density of surface immunoglobulin. The Journal of Experimental Medicine. 144: 494-506. PMID 822116 DOI: 10.1084/Jem.144.2.494  0.366
1976 Mosier DE, Scher I, Paul WE. In vitro responses of CBA/N mice: spleen cells of mice with an X-linked defect that precludes immune responses to several thymus-independent antigens can respond to TNP-lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 117: 1363-9. PMID 789772  0.359
1976 Janeway CA, Paul WE. The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes. The Journal of Experimental Medicine. 144: 1641-56. PMID 63531 DOI: 10.1084/jem.144.6.1641  0.574
1976 Janeway CA, Paul WE, Werblin TP, Lieberman R. IgG-specific helper activity of t lymphocytes from mice lacking theIr-IgG gene Immunogenetics. 3: 393-400. DOI: 10.1007/BF01576970  0.507
1975 Ben-Sasson SZ, Paul WE, Shevach EM, Green I. In vitro selection and extended culture of antigen-specific T lymphocytes. I. Description of selection culture procedure and initial characterization of selected cells. The Journal of Experimental Medicine. 142: 90-105. PMID 1097577 DOI: 10.1084/Jem.142.1.90  0.41
1975 Findelman FD, Shevach EM, Vitetta ES, Green I, Paul WE. Guinea pig immune response-related histocompatibility antigens. Partial characterization and distribution. The Journal of Experimental Medicine. 141: 27-41. PMID 1090699 DOI: 10.1084/Jem.141.1.27  0.429
1975 Janeway CA, Koren HS, Paul WE. The role of thymus-derived lymphocytes in an antibody-mediated hapten-specific helper effect. European Journal of Immunology. 5: 17-22. PMID 1086213 DOI: 10.1002/Eji.1830050105  0.587
1975 Finkelman FD, Smith AH, Scher I, Paul WE. Abnormal ratio of membrane immunoglobulin classes in mice with an X-linked B-lymphocyte defect. The Journal of Experimental Medicine. 142: 1316-21. PMID 1081577 DOI: 10.1084/Jem.142.5.1316  0.443
1975 Scher I, Steinberg AD, Berning AK, Paul WE. X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect. The Journal of Experimental Medicine. 142: 637-50. PMID 1080788 DOI: 10.1084/Jem.142.3.637  0.41
1975 Scher I, Ahmed A, Strong DM, Steinberg AD, Paul WE. X linked B lymphocyte immune defect in CBA/HN mice. I. Studies of the function and composition of spleen cells Journal of Experimental Medicine. 141: 788-803. PMID 805203 DOI: 10.1084/Jem.141.4.788  0.386
1975 Schwartz RH, Jackson L, Paul WE. T lymphocyte-enriched murine peritoneal exudate cells. I. A reliable assay for antigen-induced T lymphocyte proliferation. Journal of Immunology (Baltimore, Md. : 1950). 115: 1330-8. PMID 51890  0.389
1975 Shevach EM, Finkelman F, Ben-Sasson SZ, Green I, Paul WE. Ir genes and antigen recognition. Annals of the New York Academy of Sciences. 249: 541-7. PMID 48355 DOI: 10.1111/J.1749-6632.1975.Tb29103.X  0.306
1975 Janeway CA, Cohen BE, Ben-Sasson SZ, Paul WE. The specificity of cellular immune responses in guinea pigs. I. T cells specific for 2,4-dinitrophenyl-o-tyrosyl residues. The Journal of Experimental Medicine. 141: 42-55. PMID 46912 DOI: 10.1084/Jem.141.1.42  0.607
1974 Ben-Sasson SZ, Shevach E, Green I, Paul WE. Alloantiserum-induced inhibition of migration inhibition factor production in immune response gene-controlled immune systems. The Journal of Experimental Medicine. 140: 383-95. PMID 4603011 DOI: 10.1084/jem.140.2.383  0.334
1974 Mosier DE, Johnson BM, Paul WE, McMaster PR. Cellular requirements for the primary in vitro antibody response to DNP-ficoll Journal of Experimental Medicine. 139: 1354-1360. PMID 4596514 DOI: 10.1084/Jem.139.5.1354  0.426
1974 Shevach EM, Paul WE, Green I. Alloantiserum-induced inhibition of immune response gene product function. I. Cellular distribution of target antigens. The Journal of Experimental Medicine. 139: 661-78. PMID 4591174 DOI: 10.1084/jem.139.3.661  0.394
1974 Elfenbein GJ, Green I, Paul WE. The allogeneic effect: increased affinity of serum antibody produced during a secondary response. European Journal of Immunology. 3: 640-4. PMID 4587739 DOI: 10.1002/Eji.1830031010  0.441
1974 Gelfand MC, Elfenbein GJ, Frank MM, Paul WE. Ontogeny of B lymphocytes. II. Relative rates of appearance of lymphocytes bearing surface immunoglobulin and complement receptors Journal of Experimental Medicine. 139: 1125-1141. PMID 4545162 DOI: 10.1084/Jem.139.5.1125  0.357
1974 Harrison MR, Paul WE. Stimulus-response in the mixed lymphocyte reaction. The Journal of Experimental Medicine. 138: 1602-7. PMID 4543459 DOI: 10.1084/Jem.138.6.1602  0.41
1973 Janeway CA, Paul WE. Hapten-specific augmentation of the anti-idiotype antibody response to hapten-myeloma protein conjugates in mice. European Journal of Immunology. 3: 340-7. PMID 4758898 DOI: 10.1002/Eji.1830030605  0.569
1973 Shevach EM, Paul WE, Green I. Histocompatibility-linked immune response gene function in guinea pigs. Specific inhibition of antigen-induced lymphocyte proliferation by alloantisera. The Journal of Experimental Medicine. 136: 1207-21. PMID 4538841 DOI: 10.1084/jem.136.5.1207  0.338
1973 Katz DH, Paul WE, Benacerraf B. Carrier function in anti-hapten antibody responses. VI. Establishment of experimental conditions for either inhibitory or enhancing influences of carrier-specific cells on antibody production. Journal of Immunology (Baltimore, Md. : 1950). 110: 107-17. PMID 4119550  0.457
1973 Lieberman R, Paul WE, Humphrey W, Stimpfling JH. H-2-linked immune response (Ir) genes. Independent loci for Ir-IgG and Ir-IgA genes. The Journal of Experimental Medicine. 136: 1231-40. PMID 4117190 DOI: 10.1084/Jem.136.5.1231  0.35
1972 Green I, Paul WE, Benacerraf B. Histocompatibility-linked genetic control of the immune response to hapten guinea pig albumin conjugates in inbred guinea pigs. Journal of Immunology (Baltimore, Md. : 1950). 109: 457-63. PMID 5066344  0.379
1972 Davie JM, Paul WE, Katz DH, Benacerraf B. Hapten-specific tolerance. Preferential depression of the high affinity antibody response. The Journal of Experimental Medicine. 136: 426-38. PMID 5065752  0.467
1972 Van Boxel JA, Stobo JD, Paul WE, Green I. Antibody-dependent lymphoid cell-mediated cytotoxicity: no requirement for thymus-derived lymphocytes. Science (New York, N.Y.). 175: 194-6. PMID 5008439 DOI: 10.1126/science.175.4018.194  0.339
1972 Ellman L, Katz DH, Green I, Paul WE, Benacerraf B. Mechanisms involved in the antileukemic effect of immunocompetent allogeneic lymphoid cell transfer. Cancer Research. 32: 141-8. PMID 4400015  0.386
1972 Katz DH, Ellman L, Paul WE, Green I, Benacerraf B. Resistance of guinea pigs to leukemia following transfer of immunocompetent allogeneic lymphoid cells. Cancer Research. 32: 133-40. PMID 4400014  0.37
1972 Stobo JD, Paul WE. Functional heterogeneity of murine lymphoid cells. II. Acquisition of mitogen responsiveness and of theta antigen during the ontogeny of thymocytes and "T" lymphocytes. Cellular Immunology. 4: 367-80. PMID 4115122 DOI: 10.1016/0008-8749(72)90039-1  0.342
1971 Stupp Y, Paul WE, Benacerraf B. Structural control of immunogenicity. II. Antibody synthesis and cellular immunity in response to immunization with mono-epsilon-oligo-L-lysines. Immunology. 21: 583-94. PMID 5121756  0.411
1971 Davie JM, Rosenthal AS, Paul WE. Receptors on immunocompetent cells. 3. Specificity and nature of receptors on dinitrophenylated guinea pig albumin- 125 I-binding cells of immunized guinea pigs. The Journal of Experimental Medicine. 134: 517-31. PMID 5105301 DOI: 10.1084/jem.134.2.517  0.31
1971 Katz DH, Davie JM, Paul WE, Benacerraf B. Carrier function in anti-hapten antibody responses. IV. Experimental conditions for the induction of hapten-specific tolerance or for the stimulation of anti-hapten anamnestic responses by "nonimmunogenic" hapten-polypeptide conjugates. The Journal of Experimental Medicine. 134: 201-23. PMID 4397662 DOI: 10.1084/jem.134.1.201  0.477
1971 Katz DH, Paul WE, Goidl EA, Benacerraf B. Carrier function in anti-hapten antibody responses. 3. Stimulation of antibody synthesis and facilitation of hapten-specific secondary antibody responses by graft-versus-host reactions. The Journal of Experimental Medicine. 133: 169-86. PMID 4109111  0.485
1971 Paul WE, Stupp Y, Siskind GW, Benacerraf B. Structural control of immunogenicity. IV. Relative specificity of elicitation of cellular immune responses and of ligand binding to anti-hapten antibody after immunization with mono-epsilon-DNP-nona-L-lysine. Immunology. 21: 605-16. PMID 4107742  0.422
1971 Stupp Y, Paul WE, Benacerraf B. Structural control of immunogenicity. 3. Preparation for and elicitation of anamnestic antibody responses by oligo- and poly-lysines and their DNP derivatives. Immunology. 21: 595-603. PMID 4107741  0.401
1971 Katz DH, Paul WE, Benacerraf B. Carrier function in anti-hapten antibody responses. V. Analysis of cellular events in the enhancement of antibody responses by the "allogeneic effect" in DNP-OVA-primed guinea pigs challenged with a heterologous DNP-conjugate. Journal of Immunology (Baltimore, Md. : 1950). 107: 1319-28. PMID 4107361  0.43
1971 Paul WE, Katz DH, Benacerraf B. Augmented anti-S 3 antibody responses to an S 3 -protein conjugate. Journal of Immunology (Baltimore, Md. : 1950). 107: 685-8. PMID 4105931  0.39
1970 Davie JM, Paul WE. Receptors on immunocompetent cells. I. Receptor specificity of cells participating in a cellular immune response Cellular Immunology. 1: 404-418. PMID 5535587 DOI: 10.1016/0008-8749(70)90017-1  0.334
1970 Katz DH, Paul WE, Goidl EA, Benacerraf B. Radioresistance of cooperative function of carrier-specific lymphocytes in antihapten antibody responses. Science (New York, N.Y.). 170: 462-4. PMID 4196067  0.482
1970 Paul WE, Yoshida T, Benacerraf B. Genetic control of the specificity of anti-DNP antibodies. II. Differences in the specificity of anti-DNP antibody produced by several inbred strains of mice. Journal of Immunology (Baltimore, Md. : 1950). 105: 314-21. PMID 4194305  0.413
1970 Yoshida T, Paul WE, Benacerraf B. Genetic control of the specificity of anti-DNP antibodies. I. Differences in the specificity of anti-DNP antibody produced by mammalian species. Journal of Immunology (Baltimore, Md. : 1950). 105: 306-13. PMID 4194304  0.403
1970 Mancino D, Paul WE, Benacerraf B, Siskind GW, Ovary Z. Binding properties of anti-dinitrophenylated-bacitracin A antibodies produced in guinea pigs. Journal of Immunology (Baltimore, Md. : 1950). 104: 224-9. PMID 4189102  0.384
1970 Paul WE, Katz DH, Goidl EA, Benacerraf B. Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing anti-hapten antibody responses. The Journal of Experimental Medicine. 132: 283-99. PMID 4101345  0.5
1970 Katz DH, Paul WE, Goidl EA, Benacerraf B. Carrier function in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization. The Journal of Experimental Medicine. 132: 261-82. PMID 4101344  0.462
1969 Paul WE, Thorbecke GJ, Siskind GW, Benacerraf B. The effect of dose in tolerance induction on the subsequent response to a cross-reactive antigen. Immunology. 17: 85-92. PMID 5791607  0.384
1969 Green I, Paul WE, Benacerraf B. Genetic control of immunological responsiveness in guinea pigs to 2,4-dinitrophenyl conjugates of poly-L-arginine, protamine, and poly-L-ornithine. Proceedings of the National Academy of Sciences of the United States of America. 64: 1095-102. PMID 4984383 DOI: 10.1073/Pnas.64.3.1095  0.344
1969 Paul WE, Benacerraf B, Siskind GW, Goidl DA, Reisfeld RA. The anamnestic antibody response to type 3 specific pneumococcal polysaccharide. The Journal of Experimental Medicine. 130: 77-89. PMID 4389341 DOI: 10.1084/Jem.130.1.77  0.453
1968 Paul WE, Green I, Benacerraf B. Genetic control of the immune response to hapten-poly-L-lysine conjugates. Journal of the Reticuloendothelial Society. 5: 282-93. PMID 5673754  0.362
1968 Lamelin JP, Paul WE, Benacerraf B. The immune response of random-bred Hartley strain guinea pigs to 2,4-dinitrophenyl conjugates of a copolymer of L-glutamic acid and L-lysine. Journal of Immunology (Baltimore, Md. : 1950). 100: 1058-61. PMID 5648473  0.33
1968 Green I, Paul WE, Benacerraf B. Hapten carrier relationships in the DNP-PLL foreign albumin complex system: induction of tolerance and stimulation of cells in vitro. The Journal of Experimental Medicine. 127: 43-53. PMID 4965466  0.462
1968 Goidl EA, Paul WE, Siskind GW, Benacerraf B. The effect of antigen dose and time after immunization on the amount and affinity of anti-hapten antibody. Journal of Immunology (Baltimore, Md. : 1950). 100: 371-5. PMID 4867490  0.432
1968 Paul WE, Siskind GW, Benacerraf B. Specificity of cellular immune responses. Antigen concentration dependence of stimulation of DNA synthesis in vitro by specifically sensitized cells, as an expression of the binding characteristics of cellular antibody. The Journal of Experimental Medicine. 127: 25-42. PMID 4864671  0.48
1967 Green I, Paul WE, Benacerraf B. A study of the passive transfer of delayed hypersensitivity to DNP-poly-L-lysine and DNP-GL in responder and nonresponder guinea pigs. The Journal of Experimental Medicine. 126: 959-67. PMID 6062006  0.344
1967 Paul WE, Siskind GW, Benacerraf B. A study of the 'termination' of tolerance to BSA with DNP-BSA in rabbits: relative affinities of the antibodies for the immunizing and the paralysing antigens. Immunology. 13: 147-57. PMID 4952101  0.44
1967 Paul WE, Siskind GW, Benacerraf B, Ovary Z. Secondary antibody responses in haptenic systems: cell population selection by antigen. Journal of Immunology (Baltimore, Md. : 1950). 99: 760-70. PMID 4383410  0.461
1967 Benacerraf B, Green I, Paul WE. The Immune Response of Guinea Pigs to Hapten-poly-L-Lysine Conjugates as an Example of the Genetic Control of the Recognition of Antigenicity Cold Spring Harbor Symposia On Quantitative Biology. 32: 569-575. DOI: 10.1101/Sqb.1967.032.01.069  0.402
1967 Siskind GW, Paul WE, Benacerraf B. The use of radioactively labeled S III to study the blood clearance and the immune response of mice to pneumococcal polysaccharides Immunochemistry. 4: 455-465. DOI: 10.1016/0019-2791(67)90104-8  0.377
1966 Green I, Paul WE, Benacerraf B. The behavior of hapten-poly-L-lysine conjugates as complete antigens in genetic responder and as haptens in nonresponder guinea pigs. The Journal of Experimental Medicine. 123: 859-79. PMID 5938816  0.45
1966 Paul WE, Siskind GW, Benacerraf B. Studies on the effect of the carrier molecule on antihapten antibody synthesis. II. Carrier specificity of anti-2,4-dinitrophenyl-poly-l-lysine antibodies. The Journal of Experimental Medicine. 123: 689-705. PMID 4160399 DOI: 10.1084/jem.123.4.689  0.408
1966 Siskind GW, Paul WE, Benacerraf B. Studies on the effect of the carrier molecule on antihapten antibody synthesis. I. Effect of carrier on the nature of the antibody synthesized. The Journal of Experimental Medicine. 123: 673-88. PMID 4160398 DOI: 10.1084/jem.123.4.673  0.418
1965 Paul WE, Benacerraf B. Problems encountered in double diffusion analysis in agar of hapten specific immune systems. II. The effect of the relative solubility of the immune complexes formed by cross-reacting systems. Journal of Immunology (Baltimore, Md. : 1950). 95: 1074-9. PMID 4954748  0.351
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