Lucas D. Ward - Publications

Affiliations: 
2000-2004 University of Virginia, Charlottesville, VA 
 2004-2010 Columbia University, New York, NY 
 2010-2014 Massachusetts Institute of Technology, Cambridge, MA, United States 
 2015- Amgen Inc., Thousand Oaks, CA, United States 

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ward LD, Kellis M. HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease. Nucleic Acids Research. 44: D877-81. PMID 26657631 DOI: 10.1093/nar/gkv1340  1
2015 Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, ... Ward LD, et al. Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nature Genetics. 47: 381-6. PMID 25751624 DOI: 10.1038/ng.3245  1
2015 Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, et al. Integrative analysis of 111 reference human epigenomes. Nature. 518: 317-30. PMID 25693563 DOI: 10.1038/nature14248  1
2014 Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, et al. Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. Proceedings of the National Academy of Sciences of the United States of America. 111: E3366. PMID 25275169 DOI: 10.1073/pnas.1410434111  1
2014 Ward LD, Wang J, Bussemaker HJ. Characterizing a collective and dynamic component of chromatin immunoprecipitation enrichment profiles in yeast. Bmc Genomics. 15: 494. PMID 24947676 DOI: 10.1186/1471-2164-15-494  0.96
2014 Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, et al. Defining functional DNA elements in the human genome. Proceedings of the National Academy of Sciences of the United States of America. 111: 6131-8. PMID 24753594 DOI: 10.1073/pnas.1318948111  1
2014 Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science (New York, N.Y.). 343: 1246980. PMID 24604203 DOI: 10.1126/science.1246980  1
2013 Ward LD, Kellis M. Response to comment on "Evidence of abundant purifying selection in humans for recently acquired regulatory functions". Science (New York, N.Y.). 340: 682. PMID 23661743 DOI: 10.1126/science.1233366  1
2012 Ward LD, Kellis M. Interpreting noncoding genetic variation in complex traits and human disease. Nature Biotechnology. 30: 1095-106. PMID 23138309 DOI: 10.1038/nbt.2422  1
2012 Ward LD, Kellis M. Evidence of abundant purifying selection in humans for recently acquired regulatory functions. Science (New York, N.Y.). 337: 1675-8. PMID 22956687 DOI: 10.1126/science.1225057  1
2012 Ward LD, Kellis M. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Research. 40: D930-4. PMID 22064851 DOI: 10.1093/nar/gkr917  1
2011 Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G, Mauceli E, Ward LD, Lowe CB, Holloway AK, Clamp M, Gnerre S, et al. A high-resolution map of human evolutionary constraint using 29 mammals. Nature. 478: 476-82. PMID 21993624 DOI: 10.1038/nature10530  1
2011 Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature. 473: 43-9. PMID 21441907 DOI: 10.1038/nature09906  1
2010 Filion GJ, van Bemmel JG, Braunschweig U, Talhout W, Kind J, Ward LD, Brugman W, de Castro IJ, Kerkhoven RM, Bussemaker HJ, van Steensel B. Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. Cell. 143: 212-24. PMID 20888037 DOI: 10.1016/j.cell.2010.09.009  1
2008 Ward LD, Bussemaker HJ. Predicting functional transcription factor binding through alignment-free and affinity-based analysis of orthologous promoter sequences. Bioinformatics (Oxford, England). 24: i165-71. PMID 18586710 DOI: 10.1093/bioinformatics/btn154  1
2007 Bussemaker HJ, Ward LD, Boorsma A. Dissecting complex transcriptional responses using pathway-level scores based on prior information. Bmc Bioinformatics. 8: S6. PMID 17903287 DOI: 10.1186/1471-2105-8-S6-S6  1
2007 Bussemaker HJ, Foat BC, Ward LD. Predictive modeling of genome-wide mRNA expression: from modules to molecules. Annual Review of Biophysics and Biomolecular Structure. 36: 329-47. PMID 17311525 DOI: 10.1146/annurev.biophys.36.040306.132725  1
2006 Moorman C, Sun LV, Wang J, de Wit E, Talhout W, Ward LD, Greil F, Lu XJ, White KP, Bussemaker HJ, van Steensel B. Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 103: 12027-32. PMID 16880385 DOI: 10.1073/pnas.0605003103  1
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