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Carl W. Cotman, PhD - Publications

Affiliations: 
Neurology University of California, Irvine, Irvine, CA 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=18
Website:
http://www.faculty.uci.edu/profile.cfm?faculty_id=2273

391 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Belloso-Iguerategui A, Zamarbide M, Merino-Galan L, Rodríguez-Chinchilla T, Gago B, Santamaria E, Fernández-Irigoyen J, Cotman CW, Prieto GA, Quiroga-Varela A, Rodríguez-Oroz MC. Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit. Brain : a Journal of Neurology. PMID 37403195 DOI: 10.1093/brain/awad227  0.518
2023 Lautrup S, Myrup Holst C, Yde A, Asmussen S, Thinggaard V, Larsen K, Laursen LS, Richner M, Vaegter CB, Prieto GA, Berchtold N, Cotman CW, Stevnsner T. The role of aging and brain-derived neurotrophic factor signaling in expression of base excision repair genes in the human brain. Aging Cell. e13905. PMID 37334527 DOI: 10.1111/acel.13905  0.742
2023 McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, et al. Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 14: 1194. PMID 36864071 DOI: 10.1038/s41467-023-36930-1  0.784
2022 Ionescu-Tucker A, Tong L, Berchtold NC, Cotman CW. Inhibiting BDNF Signaling Upregulates Hippocampal H3K9me3 in a Manner Dependent On Aging and Oxidative Stress. Frontiers in Aging. 3: 796087. PMID 35821854 DOI: 10.3389/fragi.2022.796087  0.69
2022 Prieto GA, Cotman CW. Early bioenergetic and autophagy impairments at the Parkinson's disease synapse. Brain : a Journal of Neurology. PMID 35616104 DOI: 10.1093/brain/awac191  0.475
2021 Ionescu-Tucker A, Butler CW, Berchtold NC, Matheos DP, Wood MA, Cotman CW. Exercise Reduces H3K9me3 and Regulates Brain Derived Neurotrophic Factor and GABRA2 in an Age Dependent Manner. Frontiers in Aging Neuroscience. 13: 798297. PMID 34970138 DOI: 10.3389/fnagi.2021.798297  0.685
2020 McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, et al. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 11: 5370. PMID 33097708 DOI: 10.1038/s41467-020-19227-5  0.8
2020 Rodriguez-Ortiz CJ, Prieto GA, Martini AC, Forner S, Trujillo-Estrada L, LaFerla FM, Baglietto-Vargas D, Cotman CW, Kitazawa M. miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease. Aging Cell. e13118. PMID 32087004 DOI: 10.1111/Acel.13118  0.626
2019 Butler CW, Keiser AA, Kwapis JL, Berchtold NC, Wall VL, Wood MA, Cotman CW. Exercise opens a temporal window for enhanced cognitive improvement from subsequent physical activity. Learning & Memory (Cold Spring Harbor, N.Y.). 26: 485-492. PMID 31732709 DOI: 10.1101/Lm.050278.119  0.676
2019 Forner S, Martini AC, Prieto GA, Dang CT, Rodriguez-Ortiz CJ, Reyes-Ruiz JM, Trujillo-Estrada L, da Cunha C, Andrews EJ, Phan J, Vu Ha J, Chang AVZD, Levites Y, Cruz PE, Ager R, ... ... Cotman CW, et al. Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. Scientific Reports. 9: 15936. PMID 31685865 DOI: 10.1038/S41598-019-52324-0  0.696
2019 Walhovd KB, Howell GR, Ritchie SJ, Staff RT, Cotman CW. What are the earlier life contributions to reserve and resilience? Neurobiology of Aging. PMID 31307838 DOI: 10.1016/j.neurobiolaging.2019.04.014  0.309
2019 Berchtold NC, Prieto GA, Phelan M, Gillen DL, Baldi P, Bennett DA, Buchman AS, Cotman CW. Hippocampal gene expression patterns linked to late-life physical activity oppose age and AD-related transcriptional decline. Neurobiology of Aging. 78: 142-154. PMID 30927700 DOI: 10.1016/J.Neurobiolaging.2019.02.012  0.774
2019 Trujillo-Estrada L, Nguyen C, da Cunha C, Cai L, Forner S, Martini AC, Ager RR, Prieto GA, Cotman CW, Baglietto-Vargas D, LaFerla FM. Tau underlies synaptic and cognitive deficits for type 1, but not type 2 diabetes mouse models. Aging Cell. e12919. PMID 30809950 DOI: 10.1111/Acel.12919  0.66
2019 Prieto GA, Smith ED, Tong L, Nguyen M, Cotman CW. Inhibition of LTP-induced translation by IL-1β reduces the level of newly synthesized proteins in hippocampal dendrites. Acs Chemical Neuroscience. PMID 30695637 DOI: 10.1021/Acschemneuro.8B00511  0.516
2019 Prieto GA, Smith ED, Tong L, Nguyen M, Cotman CW. P2-202: INHIBITION OF ACTIVITY-DEPENDENT PROTEIN SYNTHESIS BY IL-1β IN HIPPOCAMPAL DENDRITES Alzheimer's & Dementia. 15: P654-P654. DOI: 10.1016/J.Jalz.2019.06.2609  0.502
2019 Tong L, Butler CW, Tucker AI, Prieto GA, Cotman CW. P2-179: MODULATION OF HISTONE H3 LYSINE 9 TRIMETHYLATION REGULATES SYNAPTIC PLASTICITY IN HIPPOCAMPAL NEURONS Alzheimer's & Dementia. 15: P645-P645. DOI: 10.1016/J.Jalz.2019.06.2586  0.517
2018 Baglietto-Vargas D, Prieto GA, Limon A, Forner S, Rodriguez-Ortiz CJ, Ikemura K, Ager RR, Medeiros R, Trujillo-Estrada L, Martini AC, Kitazawa M, Davila JC, Cotman CW, Gutierrez A, LaFerla FM. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. e12791. PMID 29877034 DOI: 10.1111/Acel.12791  0.685
2018 Kumar S, Frost JL, Cotman CW, Head E, Palmour R, Lemere CA, Walter J. Deposition of phosphorylated amyloid-β in brains of aged nonhuman primates and canines. Brain Pathology (Zurich, Switzerland). 28: 427-430. PMID 29740941 DOI: 10.1111/Bpa.12573  0.624
2018 Tong L, Prieto GA, Cotman CW. IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation. Journal of Neuroinflammation. 15: 127. PMID 29712570 DOI: 10.1186/S12974-018-1158-9  0.527
2018 Prieto GA, Tong L, Smith ED, Cotman CW. TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse. Neurochemical Research. PMID 29619614 DOI: 10.1007/S11064-018-2517-8  0.537
2017 Prieto GA, Cotman CW. On the road towards the global analysis of human synapses. Neural Regeneration Research. 12: 1586-1589. PMID 29171413 DOI: 10.4103/1673-5374.217321  0.54
2017 Prieto GA, Cotman CW. Cytokines and cytokine networks target neurons to modulate long-term potentiation. Cytokine & Growth Factor Reviews. PMID 28377062 DOI: 10.1016/J.Cytogfr.2017.03.005  0.542
2017 Carlos AJ, Tong L, Prieto GA, Cotman CW. IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking. Journal of Neuroinflammation. 14: 29. PMID 28153028 DOI: 10.1186/S12974-017-0803-Z  0.56
2016 Prieto GA, Trieu BH, Dang CT, Bilousova T, Gylys KH, Berchtold NC, Lynch G, Cotman CW. Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986924 DOI: 10.1523/Jneurosci.2774-16.2016  0.755
2016 Abbasi A, de Paula Vieira R, Bischof F, Walter M, Movassaghi M, Berchtold NC, Niess AM, Cotman CW, Northoff H. Sex-specific variation in signaling pathways and gene expression patterns in human leukocytes in response to endotoxin and exercise. Journal of Neuroinflammation. 13: 289. PMID 27832807 DOI: 10.1186/S12974-016-0758-5  0.667
2016 Mastroeni D, Khdour OM, Delvaux E, Nolz J, Olsen G, Berchtold N, Cotman C, Hecht SM, Coleman PD. Nuclear but not mitochondrial-encoded OXPHOS genes are altered in aging, mild cognitive impairment, and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27793643 DOI: 10.1016/J.Jalz.2016.09.003  0.7
2016 Snigdha S, Prieto GA, Petrosyan A, Loertscher BM, Dieskau AP, Overman LE, Cotman CW. H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3611-22. PMID 27013689 DOI: 10.1523/JNEUROSCI.2693-15.2016  0.511
2015 Hoffmann K, Sobol NA, Frederiksen KS, Beyer N, Vogel A, Vestergaard K, Brændgaard H, Gottrup H, Lolk A, Wermuth L, Jacobsen S, Laugesen LP, Gergelyffy RG, Høgh P, Bjerregaard E, ... ... Cotman CW, et al. Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer's Disease: A Randomized Controlled Trial. Journal of Alzheimer's Disease : Jad. PMID 26682695 DOI: 10.3233/JAD-150817  0.309
2015 Snigdha S, de Rivera C, Milgram NW, Cotman CW. Effect of mitochondrial cofactors and antioxidants supplementation on cognition in the aged canine. Neurobiology of Aging. PMID 26481404 DOI: 10.1016/J.Neurobiolaging.2015.09.015  0.311
2015 Prieto GA, Snigdha S, Baglietto-Vargas D, Smith ED, Berchtold NC, Tong L, Ajami D, LaFerla FM, Rebek J, Cotman CW. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 112: E5078-87. PMID 26305968 DOI: 10.1073/Pnas.1514486112  0.77
2015 Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, ... ... Cotman C, et al. A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. Jama Neurology. 72: 414-22. PMID 25706306 DOI: 10.1001/Jamaneurol.2014.4040  0.641
2015 Prieto GA, Snigdha S, Baglietto-Vargas D, Smith ED, Berchtold NC, Tong L, Ajami D, Laferla FM, Rebek J, Cotman CW. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus Proceedings of the National Academy of Sciences of the United States of America. 112: E5078-E5087. DOI: 10.1073/pnas.1514486112  0.752
2014 Smith ED, Prieto GA, Tong L, Sears-Kraxberger I, Rice JD, Steward O, Cotman CW. Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy. The Journal of Biological Chemistry. 289: 20615-29. PMID 24917666 DOI: 10.1074/Jbc.M114.568659  0.656
2014 Berchtold NC, Sabbagh MN, Beach TG, Kim RC, Cribbs DH, Cotman CW. Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease. Neurobiology of Aging. 35: 1961-72. PMID 24786631 DOI: 10.1016/J.Neurobiolaging.2014.03.031  0.724
2014 Rice RA, Berchtold NC, Cotman CW, Green KN. Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production. Neurobiology of Aging. 35: 1002-11. PMID 24268883 DOI: 10.1016/J.Neurobiolaging.2013.10.090  0.713
2013 Hoffmann K, Frederiksen KS, Sobol NA, Beyer N, Vogel A, Simonsen AH, Johannsen P, Lolk A, Terkelsen O, Cotman CW, Hasselbalch SG, Waldemar G. Preserving cognition, quality of life, physical health and functional ability in Alzheimer's disease: the effect of physical exercise (ADEX trial): rationale and design. Neuroepidemiology. 41: 198-207. PMID 24135720 DOI: 10.1159/000354632  0.314
2013 Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, et al. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. The Journal of Clinical Investigation. 123: 4158-69. PMID 23999428 DOI: 10.1172/Jci69003  0.723
2013 Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, et al. Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models. The American Journal of Pathology. 183: 369-81. PMID 23747948 DOI: 10.1016/J.Ajpath.2013.05.005  0.36
2013 Intlekofer KA, Berchtold NC, Malvaez M, Carlos AJ, McQuown SC, Cunningham MJ, Wood MA, Cotman CW. Exercise and sodium butyrate transform a subthreshold learning event into long-term memory via a brain-derived neurotrophic factor-dependent mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2027-34. PMID 23615664 DOI: 10.1038/Npp.2013.104  0.693
2013 Poon WW, Carlos AJ, Aguilar BL, Berchtold NC, Kawano CK, Zograbyan V, Yaopruke T, Shelanski M, Cotman CW. β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1. The Journal of Biological Chemistry. 288: 16937-48. PMID 23599427 DOI: 10.1074/Jbc.M113.463711  0.788
2013 Snigdha S, Milgram NW, Willis SL, Albert M, Weintraub S, Fortin NJ, Cotman CW. A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap. Neurobiology of Aging. 34: 1891-901. PMID 23434040 DOI: 10.1016/J.Neurobiolaging.2013.01.018  0.708
2013 Berchtold NC, Coleman PD, Cribbs DH, Rogers J, Gillen DL, Cotman CW. Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease. Neurobiology of Aging. 34: 1653-61. PMID 23273601 DOI: 10.1016/J.Neurobiolaging.2012.11.024  0.72
2013 Winchester J, Dick MB, Gillen D, Reed B, Miller B, Tinklenberg J, Mungas D, Chui H, Galasko D, Hewett L, Cotman CW. Walking stabilizes cognitive functioning in Alzheimer's disease (AD) across one year. Archives of Gerontology and Geriatrics. 56: 96-103. PMID 22959822 DOI: 10.1016/J.Archger.2012.06.016  0.717
2013 Siette J, Westbrook RF, Cotman C, Sidhu K, Zhu W, Sachdev P, Valenzuela MJ. Age-specific effects of voluntary exercise on memory and the older brain. Biological Psychiatry. 73: 435-42. PMID 22795967 DOI: 10.1016/J.Biopsych.2012.05.034  0.341
2013 Intlekofer KA, Cotman CW. Exercise counteracts declining hippocampal function in aging and Alzheimer's disease. Neurobiology of Disease. 57: 47-55. PMID 22750524 DOI: 10.1016/j.nbd.2012.06.011  0.416
2013 Nielson KA, Sandman CA, Mulnard RA, Cotman CW. In reply Journal of the American Geriatrics Society. 45: 654-655. DOI: 10.1111/j.1532-5415.1997.tb03109.x  0.602
2013 Blair L, Nordhues B, Hill S, Scaglione KM, O'Leary J, Breydo L, Bo Z, Li P, Wang L, Cotman C, Paulson H, Muschol M, Uversky V, Klengel T, Binder E, et al. The Hsp90 co-chaperone FKBP51 produces neurotoxic tau oligomers: Implication for aging and Alzheimer's disease Alzheimers & Dementia. 9: 173. DOI: 10.1016/J.Jalz.2013.05.279  0.708
2012 Kim HJ, Park JW, Byun JH, Poon WW, Cotman CW, Fowlkes CC, Jeon NL. Quantitative analysis of axonal transport by using compartmentalized and surface micropatterned culture of neurons. Acs Chemical Neuroscience. 3: 433-8. PMID 24358503 DOI: 10.1021/Cn3000026  0.705
2012 Tong L, Prieto GA, Kramár EA, Smith ED, Cribbs DH, Lynch G, Cotman CW. Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17714-24. PMID 23223292 DOI: 10.1523/Jneurosci.1253-12.2012  0.531
2012 Sárvári M, Hrabovszky E, Kalló I, Solymosi N, Likó I, Berchtold N, Cotman C, Liposits Z. Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: Rat and human studies identify strikingly similar changes Journal of Neuroinflammation. 9. PMID 23206327 DOI: 10.1186/1742-2094-9-264  0.674
2012 Cribbs DH, Berchtold NC, Perreau V, Coleman PD, Rogers J, Tenner AJ, Cotman CW. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. Journal of Neuroinflammation. 9: 179. PMID 22824372 DOI: 10.1186/1742-2094-9-179  0.708
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Cotman CW, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801  0.722
2012 Chapman SB, Cotman CW, Fillit HM, Gallagher M, van Dyck CH. Clinical trials: new opportunities. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 773-80. PMID 22570132 DOI: 10.1093/gerona/gls126  0.327
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... Cotman CW, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  0.319
2012 Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman JM, Jicha GA, Cotman C, Cottrell B, Montine TJ, Thomas RG, Aisen P. Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. Archives of Neurology. 69: 836-41. PMID 22431837 DOI: 10.1001/Archneurol.2012.85  0.302
2012 Snigdha S, Smith ED, Prieto GA, Cotman CW. Caspase-3 activation as a bifurcation point between plasticity and cell death. Neuroscience Bulletin. 28: 14-24. PMID 22233886 DOI: 10.1007/S12264-012-1057-5  0.557
2012 Snigdha S, Astarita G, Piomelli D, Cotman CW. Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. Neuroscience. 202: 326-33. PMID 22183056 DOI: 10.1016/j.neuroscience.2011.12.002  0.358
2012 Jung KM, Astarita G, Yasar S, Vasilevko V, Cribbs DH, Head E, Cotman CW, Piomelli D. An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. Neurobiology of Aging. 33: 1522-32. PMID 21546126 DOI: 10.1016/j.neurobiolaging.2011.03.012  0.66
2012 Fahnestock M, Marchese M, Head E, Pop V, Michalski B, Milgram WN, Cotman CW. BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog. Neurobiology of Aging. 33: 546-54. PMID 20447733 DOI: 10.1016/J.Jveb.2009.12.005  0.786
2012 Pop V, Head E, Berchtold NC, Glabe CG, Studzinski CM, Weidner AM, Murphy MP, Cotman CW. Aβ aggregation profiles and shifts in APP processing favor amyloidogenesis in canines. Neurobiology of Aging. 33: 108-20. PMID 20434811 DOI: 10.1016/J.Neurobiolaging.2010.02.008  0.801
2012 Cotman CW, Anderson AJ. Retention of Function in the Aged Brain: The Pivotal Role of β-Amyloid Brain and Memory: Modulation and Mediation of Neuroplasticity. DOI: 10.1093/acprof:oso/9780195082944.003.0008  0.581
2012 Poon W, Carlos A, Aguilar B, Cotman C. P2-079: Neutrophin-trafficking deficits are mediated by impaired ubiquitin recycling in Alzheimer's disease Alzheimer's & Dementia. 8: P291-P291. DOI: 10.1016/J.Jalz.2012.05.783  0.646
2011 Astarita G, Jung KM, Vasilevko V, Dipatrizio NV, Martin SK, Cribbs DH, Head E, Cotman CW, Piomelli D. Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease. Plos One. 6: e24777. PMID 22046234 DOI: 10.1371/journal.pone.0024777  0.648
2011 Snigdha S, Berchtold N, Astarita G, Saing T, Piomelli D, Cotman CW. Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain. Plos One. 6: e24652. PMID 21931796 DOI: 10.1371/Journal.Pone.0024652  0.712
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Cotman CW, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  0.71
2011 Poon WW, Blurton-Jones M, Tu CH, Feinberg LM, Chabrier MA, Harris JW, Jeon NL, Cotman CW. β-Amyloid impairs axonal BDNF retrograde trafficking. Neurobiology of Aging. 32: 821-33. PMID 19540623 DOI: 10.1016/J.Neurobiolaging.2009.05.012  0.792
2011 Cotman CW, Head E. The canine model of human aging and disease Advances in Alzheimer's Disease. 1: 15-38. DOI: 10.3233/978-1-60750-733-8-15  0.558
2011 Poon W, Aguilar B, Feinberg L, Seow J, Tu T, Cedeno A, Carlos A, Cotman C. P4-194: Neural stem cells rescue deficits in Alzheimer's transgenic mice Alzheimer's & Dementia. 7: S771-S772. DOI: 10.1016/J.Jalz.2011.05.2217  0.77
2010 Astarita G, Jung KM, Berchtold NC, Nguyen VQ, Gillen DL, Head E, Cotman CW, Piomelli D. Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease. Plos One. 5: e12538. PMID 20838618 DOI: 10.1371/Journal.Pone.0012538  0.771
2010 Pop V, Head E, Hill MA, Gillen D, Berchtold NC, Muggenburg BA, Milgram NW, Murphy MP, Cotman CW. Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9831-9. PMID 20660265 DOI: 10.1523/Jneurosci.6194-09.2010  0.795
2010 Coskun PE, Wyrembak J, Derbereva O, Melkonian G, Doran E, Lott IT, Head E, Cotman CW, Wallace DC. Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia. Journal of Alzheimer's Disease : Jad. 20: S293-310. PMID 20463402 DOI: 10.3233/JAD-2010-100351  0.647
2010 Vasilevko V, Pop V, Kim HJ, Saing T, Glabe CC, Milton S, Barrett EG, Cotman CW, Cribbs DH, Head E. Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta. Neurobiology of Disease. 39: 301-10. PMID 20451612 DOI: 10.1016/j.nbd.2010.04.014  0.736
2010 Berchtold NC, Castello N, Cotman CW. Exercise and time-dependent benefits to learning and memory. Neuroscience. 167: 588-97. PMID 20219647 DOI: 10.1016/J.Neuroscience.2010.02.050  0.683
2010 Christie L, Opii W, Head E, Araujo J, De Rivera C, Milgram N, Cotman C. Effects of acetyl-L-carnitine and Lipoic Acid supplementation on cognition in aged beagles Journal of Veterinary Behavior. 5: 160. DOI: 10.1016/j.jveb.2009.12.006  0.593
2010 Poon WW, Carlos AJ, Cotman CW, Rohn TT. P2-212: Overexpression of Bcl-2 in APP transgenic mice reduces amyloid pathology Alzheimer's & Dementia. 6: S376-S376. DOI: 10.1016/J.Jalz.2010.05.1261  0.63
2010 Soi-Ampornkul R, Tong L, Thangnipon W, Cotman CW, Balazs R. P2-094: The reduction of neurotrophin-3 induced signal transduction by interleukin-1β in cultured cortical neurons: A model of Alzheimer's disease Alzheimer's & Dementia. 6: S340-S341. DOI: 10.1016/j.jalz.2010.05.1140  0.306
2009 Christie LA, Opii WO, Head E, Araujo JA, de Rivera C, Milgram NW, Cotman CW. Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles. Experimental Gerontology. 44: 752-9. PMID 19735717 DOI: 10.1016/J.Exger.2009.08.012  0.619
2009 Head E, Nukala VN, Fenoglio KA, Muggenburg BA, Cotman CW, Sullivan PG. Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging. Experimental Neurology. 220: 171-6. PMID 19703441 DOI: 10.1016/J.Expneurol.2009.08.014  0.618
2009 Nichol K, Deeny SP, Seif J, Camaclang K, Cotman CW. Exercise improves cognition and hippocampal plasticity in APOE epsilon4 mice. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 5: 287-94. PMID 19560099 DOI: 10.1016/J.Jalz.2009.02.006  0.305
2009 Taylor AM, Berchtold NC, Perreau VM, Tu CH, Li Jeon N, Cotman CW. Axonal mRNA in uninjured and regenerating cortical mammalian axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4697-707. PMID 19369540 DOI: 10.1523/Jneurosci.6130-08.2009  0.706
2009 Astarita G, Head E, Cotman CW, Piomelli D. P3-011: Omega-3 fatty acid deficit in Alzheimer's disease Alzheimer's & Dementia. 5: P343-P343. DOI: 10.1016/j.jalz.2009.04.1188  0.602
2008 Cotman CW, Head E. The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches. Journal of Alzheimer's Disease : Jad. 15: 685-707. PMID 19096165 DOI: 10.3233/Jad-2008-15413  0.677
2008 Bain LJ, Jedrziewski K, Morrison-Bogorad M, Albert M, Cotman C, Hendrie H, Trojanowski JQ. Healthy brain aging: A meeting report from the Sylvan M. Cohen Annual Retreat of the University of Pennsylvania Institute on Aging Alzheimer's and Dementia. 4: 443-446. PMID 18945646 DOI: 10.1016/J.Jalz.2008.08.006  0.364
2008 Berchtold NC, Cribbs DH, Coleman PD, Rogers J, Head E, Kim R, Beach T, Miller C, Troncoso J, Trojanowski JQ, Zielke HR, Cotman CW. Gene expression changes in the course of normal brain aging are sexually dimorphic. Proceedings of the National Academy of Sciences of the United States of America. 105: 15605-10. PMID 18832152 DOI: 10.1073/Pnas.0806883105  0.774
2008 Christie LA, Saunders RC, Kowalska DM, MacKay WA, Head E, Cotman CW. Rhinal and dorsolateral prefrontal cortex lesions produce selective impairments in object and spatial learning and memory in canines. The Journal of Comparative Neurology. 511: 257-70. PMID 18792072 DOI: 10.1002/cne.21821  0.585
2008 Nichol KE, Poon WW, Parachikova AI, Cribbs DH, Glabe CG, Cotman CW. Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid. Journal of Neuroinflammation. 5: 13. PMID 18400101 DOI: 10.1186/1742-2094-5-13  0.79
2008 Parachikova A, Nichol KE, Cotman CW. Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition. Neurobiology of Disease. 30: 121-9. PMID 18258444 DOI: 10.1016/J.Nbd.2007.12.008  0.783
2008 Siegenthaler MM, Berchtold NC, Cotman CW, Keirstead HS. Voluntary running attenuates age-related deficits following SCI. Experimental Neurology. 210: 207-16. PMID 18164294 DOI: 10.1016/J.Expneurol.2007.10.019  0.688
2008 Soiampornkul R, Tong L, Thangnipon W, Balazs R, Cotman CW. Interleukin-1beta interferes with signal transduction induced by neurotrophin-3 in cortical neurons. Brain Research. 1188: 189-97. PMID 18036576 DOI: 10.1016/j.brainres.2007.10.051  0.31
2008 Siwak-Tapp CT, Head E, Muggenburg BA, Milgram NW, Cotman CW. Region specific neuron loss in the aged canine hippocampus is reduced by enrichment. Neurobiology of Aging. 29: 39-50. PMID 17092609 DOI: 10.1016/J.Neurobiolaging.2006.09.018  0.629
2008 Opii WO, Joshi G, Head E, Milgram NW, Muggenburg BA, Klein JB, Pierce WM, Cotman CW, Butterfield DA. Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease. Neurobiology of Aging. 29: 51-70. PMID 17055614 DOI: 10.1016/J.Neurobiolaging.2006.09.012  0.643
2008 Cotman CW. Keynote - Exercise Regulates Synaptic Plasticity and Delays Age-Related Brain Pathology and Dysfunction Medicine & Science in Sports & Exercise. 40: 69. DOI: 10.1249/01.mss.0000321387.78798.38  0.338
2007 Cotman CW, Berchtold NC. Physical activity and the maintenance of cognition: learning from animal models. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 3: S30-7. PMID 19595972 DOI: 10.1016/J.Jalz.2007.01.013  0.706
2007 Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL, Rasool S, Gurlo T, Butler P, Glabe CG. Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Molecular Neurodegeneration. 2: 18. PMID 17897471 DOI: 10.1186/1750-1326-2-18  0.619
2007 Cotman CW, Berchtold NC, Christie LA. Exercise builds brain health: key roles of growth factor cascades and inflammation. Trends in Neurosciences. 30: 464-72. PMID 17765329 DOI: 10.1016/J.Tins.2007.06.011  0.695
2007 Parachikova A, Cotman CW. Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease. Neurobiology of Disease. 28: 143-53. PMID 17764962 DOI: 10.1016/J.Nbd.2007.07.001  0.793
2007 Nichol KE, Parachikova AI, Cotman CW. Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse. Behavioural Brain Research. 184: 124-32. PMID 17698211 DOI: 10.1016/J.Bbr.2007.06.027  0.786
2007 Siwak-Tapp CT, Head E, Muggenburg BA, Milgram NW, Cotman CW. Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function. Neurobiology of Learning and Memory. 88: 249-59. PMID 17587610 DOI: 10.1016/J.Nlm.2007.05.001  0.648
2007 Engesser-Cesar C, Ichiyama RM, Nefas AL, Hill MA, Edgerton VR, Cotman CW, Anderson AJ. Wheel running following spinal cord injury improves locomotor recovery and stimulates serotonergic fiber growth. The European Journal of Neuroscience. 25: 1931-9. PMID 17439482 DOI: 10.1111/J.1460-9568.2007.05469.X  0.572
2007 Celsi F, Svedberg M, Unger C, Cotman CW, Carrì MT, Ottersen OP, Nordberg A, Torp R. Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress. Neurobiology of Disease. 26: 342-52. PMID 17344052 DOI: 10.1016/J.Nbd.2006.12.022  0.374
2007 Christie LA, Su JH, Tu CH, Dick MC, Zhou J, Cotman CW. Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains. Neurobiology of Disease. 26: 165-73. PMID 17292615 DOI: 10.1016/j.nbd.2006.12.017  0.355
2007 Engesser-Cesar C, Anderson AJ, Cotman CW. Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord. Neuroscience. 144: 1033-44. PMID 17137724 DOI: 10.1016/J.Neuroscience.2006.10.016  0.576
2007 Sharman EH, Bondy SC, Sharman KG, Lahiri D, Cotman CW, Perreau VM. Effects of melatonin and age on gene expression in mouse CNS using microarray analysis. Neurochemistry International. 50: 336-44. PMID 17118492 DOI: 10.1016/J.Neuint.2006.09.001  0.307
2007 Rhee SW, Taylor AM, Cribbs DH, Cotman CW, Jeon NL. External force-assisted cell positioning inside microfluidic devices. Biomedical Microdevices. 9: 15-23. PMID 17091393 DOI: 10.1007/S10544-006-9002-X  0.435
2007 Perreau VM, Bondy SC, Cotman CW, Sharman KG, Sharman EH. Melatonin treatment in old mice enables a more youthful response to LPS in the brain. Journal of Neuroimmunology. 182: 22-31. PMID 17070935 DOI: 10.1016/J.Jneuroim.2006.09.005  0.304
2007 Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiology of Aging. 28: 1821-33. PMID 17052803 DOI: 10.1016/J.Neurobiolaging.2006.08.014  0.801
2007 Cotman C. S1-01-04: What goes wrong with the brain during aging Alzheimer's & Dementia. 3: S165-S165. DOI: 10.1016/j.jalz.2007.04.100  0.315
2006 Dishman RK, Berthoud HR, Booth FW, Cotman CW, Edgerton VR, Fleshner MR, Gandevia SC, Gomez-Pinilla F, Greenwood BN, Hillman CH, Kramer AF, Levin BE, Moran TH, Russo-Neustadt AA, Salamone JD, et al. Neurobiology of exercise. Obesity (Silver Spring, Md.). 14: 345-56. PMID 16648603 DOI: 10.1038/Oby.2006.46  0.309
2006 Studzinski CM, Christie LA, Araujo JA, Burnham WM, Head E, Cotman CW, Milgram NW. Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia. Neurobiology of Learning and Memory. 86: 197-204. PMID 16616528 DOI: 10.1016/J.Nlm.2006.02.005  0.649
2006 Head E, Barrett EG, Murphy MP, Das P, Nistor M, Sarsoza F, Glabe CC, Kayed R, Milton S, Vasilevko V, Milgram NW, Agadjanyan MG, Cribbs DH, Cotman CW. Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta. Vaccine. 24: 2824-34. PMID 16460841 DOI: 10.1016/J.Vaccine.2005.12.058  0.609
2006 Chubb C, Inagaki Y, Sheu P, Cummings B, Wasserman A, Head E, Cotman C. BioVision: an application for the automated image analysis of histological sections. Neurobiology of Aging. 27: 1462-76. PMID 16271803 DOI: 10.1016/J.Neurobiolaging.2005.08.023  0.607
2006 Nichol KE, Parachikova A, Caiozzo V, Cotman C. Exercise Alters Immune Response in Hippocampus of Transgenic Alzheimer Mouse Model and Improves Reference Memory Medicine & Science in Sports & Exercise. 38: S309. DOI: 10.1249/00005768-200605001-02206  0.772
2006 Rodriguez-Ortiz CJ, Prieto GA, Cotman CW, Kitazawa M. P1-236: Aβ OLIGOMERS IMPAIR PLASTICITY BY DYSREGULATING MIR-181A IN PRIMARY HIPPOCAMPAL CULTURES Alzheimer's & Dementia. 14: P368-P368. DOI: 10.1016/J.Jalz.2018.06.241  0.504
2006 Buttini M, Chen M, Head E, Cotman C, Games D. O1-01-04: Inflammatory cell infiltrates are commonly associated with brain vasculature and cerebral amyloid angiopathy in Alzheimer's disease Alzheimer's & Dementia. 2: S8-S9. DOI: 10.1016/j.jalz.2006.05.037  0.626
2005 Araujo JA, Studzinski CM, Head E, Cotman CW, Milgram NW. Assessment of nutritional interventions for modification of age-associated cognitive decline using a canine model of human aging. Age (Dordrecht, Netherlands). 27: 27-37. PMID 23598601 DOI: 10.1007/S11357-005-4001-Z  0.63
2005 Cotman CW. The role of neurotrophins in brain aging: a perspective in honor of Regino Perez-Polo. Neurochemical Research. 30: 877-81. PMID 16187222 DOI: 10.1007/s11064-005-6960-y  0.366
2005 Roudebush P, Zicker SC, Cotman CW, Milgram NW, Muggenburg BA, Head E. Nutritional management of brain aging in dogs. Journal of the American Veterinary Medical Association. 227: 722-8. PMID 16178393 DOI: 10.2460/Javma.2005.227.722  0.605
2005 Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL. A microfluidic culture platform for CNS axonal injury, regeneration and transport. Nature Methods. 2: 599-605. PMID 16094385 DOI: 10.1038/Nmeth777  0.647
2005 Newman J, Rissman RA, Sarsoza F, Kim RC, Dick M, Bennett DA, Cotman CW, Rohn TT, Head E. Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology. Acta Neuropathologica. 110: 135-44. PMID 15986225 DOI: 10.1007/S00401-005-1027-3  0.722
2005 Berchtold NC, Chinn G, Chou M, Kesslak JP, Cotman CW. Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus. Neuroscience. 133: 853-61. PMID 15896913 DOI: 10.1016/J.Neuroscience.2005.03.026  0.678
2005 Perreau VM, Adlard PA, Anderson AJ, Cotman CW. Exercise-induced gene expression changes in the rat spinal cord. Gene Expression. 12: 107-21. PMID 15892452 DOI: 10.3727/000000005783992115  0.586
2005 Adlard PA, Perreau VM, Pop V, Cotman CW. Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4217-21. PMID 15858047 DOI: 10.1523/JNEUROSCI.0496-05.2005  0.676
2005 Siwak CT, Tapp PD, Head E, Zicker SC, Murphey HL, Muggenburg BA, Ikeda-Douglas CJ, Cotman CW, Milgram NW. Chronic antioxidant and mitochondrial cofactor administration improves discrimination learning in aged but not young dogs. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 461-9. PMID 15795055 DOI: 10.1016/J.Pnpbp.2004.12.011  0.614
2005 Christie LA, Studzinski CM, Araujo JA, Leung CS, Ikeda-Douglas CJ, Head E, Cotman CW, Milgram NW. A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 361-9. PMID 15795044 DOI: 10.1016/J.Pnpbp.2004.12.002  0.585
2005 Cotman CW, Poon WW, Rissman RA, Blurton-Jones M. The role of caspase cleavage of tau in Alzheimer disease neuropathology. Journal of Neuropathology and Experimental Neurology. 64: 104-12. PMID 15751224 DOI: 10.1093/Jnen/64.2.104  0.802
2005 Head E, Moffat K, Das P, Sarsoza F, Poon WW, Landsberg G, Cotman CW, Murphy MP. Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats. Neurobiology of Aging. 26: 749-63. PMID 15708450 DOI: 10.1016/J.Neurobiolaging.2004.06.015  0.773
2005 Engesser-Cesar C, Anderson AJ, Basso DM, Edgerton VR, Cotman CW. Voluntary wheel running improves recovery from a moderate spinal cord injury. Journal of Neurotrauma. 22: 157-71. PMID 15665610 DOI: 10.1089/Neu.2005.22.157  0.578
2005 Adlard PA, Perreau VM, Cotman CW. The exercise-induced expression of BDNF within the hippocampus varies across life-span. Neurobiology of Aging. 26: 511-20. PMID 15653179 DOI: 10.1016/j.neurobiolaging.2004.05.006  0.318
2005 Rhee SW, Taylor AM, Tu CH, Cribbs DH, Cotman CW, Jeon NL. Patterned cell culture inside microfluidic devices. Lab On a Chip. 5: 102-7. PMID 15616747 DOI: 10.1039/B403091E  0.438
2005 Milgram NW, Head E, Zicker SC, Ikeda-Douglas CJ, Murphey H, Muggenburg B, Siwak C, Tapp D, Cotman CW. Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study. Neurobiology of Aging. 26: 77-90. PMID 15585348 DOI: 10.1016/J.Neurobiolaging.2004.02.014  0.596
2005 Berchtold NC, Cotman CW, Strobel G, Xiao Q, Trakya FK, Pochet R, Lessmann V, Wang D, Holcomb L, Fahnestock M, Duong T, Busciglio J, Zhu S. Alzheimer research forum live discussion: Brain derived neurotrophic factor and Alzheimer's disease - What is the connection? Journal of Alzheimer's Disease. 7: 173-180.  0.686
2005 Head E, Cotman CW, Zicker SC, Milgram NW. The use of dietary antioxidants and mitochondrial co-factors to promote successful aging Current Topics in Nutraceutical Research. 3: 85-94.  0.539
2004 Anderson AJ, Robert S, Huang W, Young W, Cotman CW. Activation of complement pathways after contusion-induced spinal cord injury. Journal of Neurotrauma. 21: 1831-46. PMID 15684772 DOI: 10.1089/Neu.2004.21.1831  0.577
2004 Liu J, Head E, Kuratsune H, Cotman CW, Ames BN. Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Annals of the New York Academy of Sciences. 1033: 117-31. PMID 15591009 DOI: 10.1196/Annals.1320.011  0.59
2004 Tapp PD, Siwak CT, Gao FQ, Chiou JY, Black SE, Head E, Muggenburg BA, Cotman CW, Milgram NW, Su MY. Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8205-13. PMID 15385603 DOI: 10.1523/Jneurosci.1339-04.2004  0.637
2004 Tong L, Balazs R, Thornton PL, Cotman CW. Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6799-809. PMID 15282285 DOI: 10.1523/JNEUROSCI.5463-03.2004  0.366
2004 Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. The Journal of Clinical Investigation. 114: 121-30. PMID 15232619 DOI: 10.1172/Jci20640  0.809
2004 Tapp PD, Siwak CT, Head E, Cotman CW, Murphey H, Muggenburg BA, Ikeda-Douglas C, Milgram NW. Concept abstraction in the aging dog: development of a protocol using successive discrimination and size concept tasks. Behavioural Brain Research. 153: 199-210. PMID 15219721 DOI: 10.1016/J.Bbr.2003.12.003  0.589
2004 Johnson JK, Vogt BA, Kim R, Cotman CW, Head E. Isolated executive impairment and associated frontal neuropathology. Dementia and Geriatric Cognitive Disorders. 17: 360-7. PMID 15178954 DOI: 10.1159/000078183  0.639
2004 Adlard PA, Perreau VM, Engesser-Cesar C, Cotman CW. The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise. Neuroscience Letters. 363: 43-8. PMID 15157993 DOI: 10.1016/j.neulet.2004.03.058  0.304
2004 Milgram NW, Head E, Zicker SC, Ikeda-Douglas C, Murphey H, Muggenberg BA, Siwak CT, Tapp PD, Lowry SR, Cotman CW. Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs. Experimental Gerontology. 39: 753-65. PMID 15130670 DOI: 10.1016/J.Exger.2004.01.007  0.597
2004 Whitman GT, Cotman CW. Oligodendrocyte degeneration in AD. Neurobiology of Aging. 25: 33-6. PMID 14675727 DOI: 10.1016/j.neurobiolaging.2003.06.001  0.361
2004 Moore P, Dennis K, DeVita C, Grossman M, Lebert F, Stekke W, Hasenbroekx C, Pasquier F, Johnson JK, Vogt BA, Kim R, Cotman CW, Head E, Comstock H, Pickering-Brown S, et al. Contents Vol. 17, 2004 Dementia and Geriatric Cognitive Disorders. 17: 387-389. DOI: 10.1159/000078837  0.54
2004 Moore P, Dennis K, DeVita C, Grossman M, Lebert F, Stekke W, Hasenbroekx C, Pasquier F, Johnson JK, Vogt BA, Kim R, Cotman CW, Head E, Comstock H, Pickering-Brown S, et al. Subject Index Vol. 17, 2004 Dementia and Geriatric Cognitive Disorders. 17: 384-385. DOI: 10.1159/000078836  0.542
2004 Tong L, Sheng H, Martinez-Coria H, Balazs R, Cotman CW. P3-312 Expression of certain activity-dependent genes, implicated in neuronal plasticity, is impaired in the hippocampus of amyloid precursor protein transgenic mice Neurobiology of Aging. 25: S444. DOI: 10.1016/S0197-4580(04)81462-3  0.33
2004 Tapp D, Siwak CT, Gao FQ, Chiou J, Black SE, Head E, Muggenburg BA, Cotman CW, Milgram NW, Su M. P3-066 Changes in frontal lobe volume, executive function, and amyloid load in a canine model of aging Neurobiology of Aging. 25: S371. DOI: 10.1016/S0197-4580(04)81218-1  0.609
2004 Kesslak JP, Chuang KR, Berchtold NC, Cotman C. Erratum to “Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in rats” [Neurosci. Lett. 353 (2003) 95–98] Neuroscience Letters. 369: 85. DOI: 10.1016/J.Neulet.2004.07.005  0.686
2003 Taylor AM, Rhee SW, Tu CH, Cribbs DH, Cotman CW, Jeon NL. Microfluidic Multicompartment Device for Neuroscience Research. Langmuir : the Acs Journal of Surfaces and Colloids. 19: 1551-1556. PMID 20725530 DOI: 10.1021/la026417v  0.373
2003 Haier RJ, Alkire MT, White NS, Uncapher MR, Head E, Lott IT, Cotman CW. Temporal cortex hypermetabolism in Down syndrome prior to the onset of dementia. Neurology. 61: 1673-9. PMID 14694028 DOI: 10.1212/01.Wnl.0000098935.36984.25  0.645
2003 Zhao M, Su J, Head E, Cotman CW. Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease. Neurobiology of Disease. 14: 391-403. PMID 14678756 DOI: 10.1016/j.nbd.2003.07.006  0.654
2003 Nippak PM, Chan AD, Campbell Z, Muggenburg B, Head E, Ikeda-Douglas CJ, Murphey H, Cotman CW, Milgram NW. Response latency in Canis familiaris: mental ability or mental strategy? Behavioral Neuroscience. 117: 1066-75. PMID 14570555 DOI: 10.1037/0735-7044.117.5.1066  0.61
2003 Head E, Lott IT, Hof PR, Bouras C, Su JH, Kim R, Haier R, Cotman CW. Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome. Journal of Neuropathology and Experimental Neurology. 62: 917-26. PMID 14533781 DOI: 10.1093/Jnen/62.9.917  0.66
2003 Siwak CT, Tapp PD, Zicker SC, Murphey HL, Muggenburg BA, Head E, Cotman CW, Milgram NW. Locomotor activity rhythms in dogs vary with age and cognitive status. Behavioral Neuroscience. 117: 813-24. PMID 12931965 DOI: 10.1037/0735-7044.117.4.813  0.608
2003 Bi X, Head E, Cotman CW, Lynch G. Spatial patterns of mammalian brain aging: distribution of cathepsin D-immunoreactive cell bodies and dystrophic dendrites in aging dogs resembles that in Alzheimer's disease. The Journal of Comparative Neurology. 464: 371-81. PMID 12900930 DOI: 10.1002/cne.10795  0.655
2003 Torp R, Ottersen OP, Cotman CW, Head E. Identification of neuronal plasma membrane microdomains that colocalize beta-amyloid and presenilin: implications for beta-amyloid precursor protein processing. Neuroscience. 120: 291-300. PMID 12890502 DOI: 10.1016/S0306-4522(03)00320-8  0.639
2003 Garcia C, Chen MJ, Garza AA, Cotman CW, Russo-Neustadt A. The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity. Neuroscience. 119: 721-32. PMID 12809693 DOI: 10.1016/S0306-4522(03)00192-1  0.311
2003 Su JH, Anderson AJ, Cribbs DH, Tu C, Tong L, Kesslack P, Cotman CW. Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death. Neurobiology of Disease. 12: 182-93. PMID 12742739 DOI: 10.1016/S0969-9961(02)00019-0  0.642
2003 Ramsden M, Berchtold NC, Patrick Kesslak J, Cotman CW, Pike CJ. Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion. Brain Research. 971: 239-44. PMID 12706240 DOI: 10.1016/S0006-8993(03)02365-5  0.686
2003 Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science (New York, N.Y.). 300: 486-9. PMID 12702875 DOI: 10.1126/Science.1079469  0.636
2003 Zhao M, Cribbs DH, Anderson AJ, Cummings BJ, Su JH, Wasserman AJ, Cotman CW. The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain. Neurochemical Research. 28: 307-18. PMID 12608703 DOI: 10.1023/A:1022337519035  0.625
2003 Tapp PD, Siwak CT, Estrada J, Head E, Muggenburg BA, Cotman CW, Milgram NW. Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 64-73. PMID 12551965 DOI: 10.1101/Lm.54403  0.612
2003 Head E, Milgram NW, Cotman CW. Neuropathology in ageing dogs | Neuropathologische Veränderungen bei alternden Hunden Praktische Tierarzt. 84: 192-195.  0.561
2002 Rohn TT, Rissman RA, Head E, Cotman CW. Caspase Activation in the Alzheimer's Disease Brain: Tortuous and Torturous. Drug News & Perspectives. 15: 549-557. PMID 12677194 DOI: 10.1358/dnp.2002.15.9.740233  0.728
2002 Rohn TT, Rissman RA, Davis MC, Kim YE, Cotman CW, Head E. Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain. Neurobiology of Disease. 11: 341-54. PMID 12505426 DOI: 10.1006/nbdi.2002.0549  0.732
2002 Aliev G, Seyidova D, Neal ML, Shi J, Lamb BT, Siedlak SL, Vinters HV, Head E, Perry G, Lamanna JC, Friedland RP, Cotman CW. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Annals of the New York Academy of Sciences. 977: 45-64. PMID 12480733 DOI: 10.1111/J.1749-6632.2002.Tb04798.X  0.64
2002 Milgram NW, Head E, Muggenburg B, Holowachuk D, Murphey H, Estrada J, Ikeda-Douglas CJ, Zicker SC, Cotman CW. Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy. Neuroscience and Biobehavioral Reviews. 26: 679-95. PMID 12479842 DOI: 10.1016/S0149-7634(02)00039-8  0.604
2002 Cotman CW, Head E, Muggenburg BA, Zicker S, Milgram NW. Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction. Neurobiology of Aging. 23: 809-18. PMID 12392784 DOI: 10.1016/S0197-4580(02)00073-8  0.645
2002 Milgram NW, Zicker SC, Head E, Muggenburg BA, Murphey H, Ikeda-Douglas CJ, Cotman CW. Dietary enrichment counteracts age-associated cognitive dysfunction in canines. Neurobiology of Aging. 23: 737-45. PMID 12392778 DOI: 10.1016/S0197-4580(02)00020-9  0.614
2002 SantaCruz KS, Tasaki CS, Kim RC, Cotman CW. Brainstem and cortical Lewy bodies in patients presenting clinically with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 4: 11-7. PMID 12214014 DOI: 10.3233/Jad-2002-4102  0.327
2002 Head E, Lott IT, Cribbs DH, Cotman CW, Rohn TT. Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome. Neuroscience Letters. 330: 99-103. PMID 12213643 DOI: 10.1016/S0304-3940(02)00705-X  0.645
2002 Albert KA, Hemmings HC, Adamo AI, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P. Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Archives of General Psychiatry. 59: 705-12. PMID 12150646 DOI: 10.1001/Archpsyc.59.8.705  0.472
2002 Head E, Liu J, Hagen TM, Muggenburg BA, Milgram NW, Ames BN, Cotman CW. Oxidative damage increases with age in a canine model of human brain aging. Journal of Neurochemistry. 82: 375-81. PMID 12124438 DOI: 10.1046/J.1471-4159.2002.00969.X  0.638
2002 Berchtold NC, Kesslak JP, Cotman CW. Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum. Journal of Neuroscience Research. 68: 511-21. PMID 12111841 DOI: 10.1002/Jnr.10256  0.71
2002 Cotman CW, Berchtold NC. Exercise: a behavioral intervention to enhance brain health and plasticity. Trends in Neurosciences. 25: 295-301. PMID 12086747 DOI: 10.1016/S0166-2236(02)02143-4  0.699
2002 Su JH, Kesslak JP, Head E, Cotman CW. Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain. Acta Neuropathologica. 104: 1-6. PMID 12070657 DOI: 10.1007/s00401-002-0548-2  0.646
2002 Chan AD, Nippak PM, Murphey H, Ikeda-Douglas CJ, Muggenburg B, Head E, Cotman CW, Milgram NW. Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility. Behavioral Neuroscience. 116: 443-54. PMID 12049325 DOI: 10.1037/0735-7044.116.3.443  0.611
2002 Soreghan B, Pike C, Kayed R, Tian W, Milton S, Cotman C, Glabe CG. The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its conformation, aggregation, and neurotoxic properties. Neuromolecular Medicine. 1: 81-94. PMID 12025818 DOI: 10.1385/Nmm:1:1:81  0.303
2002 Cotman CW, Engesser-Cesar C. Exercise enhances and protects brain function. Exercise and Sport Sciences Reviews. 30: 75-9. PMID 11991541 DOI: 10.1097/00003677-200204000-00006  0.335
2002 Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, Cotman CW, Ames BN. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proceedings of the National Academy of Sciences of the United States of America. 99: 2356-61. PMID 11854529 DOI: 10.1073/Pnas.261709299  0.606
2001 Berchtold NC, Kesslak JP, Pike CJ, Adlard PA, Cotman CW. Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus. The European Journal of Neuroscience. 14: 1992-2002. PMID 11860494 DOI: 10.1046/J.0953-816X.2001.01825.X  0.691
2001 Tong L, Shen H, Perreau VM, Balazs R, Cotman CW. Effects of exercise on gene-expression profile in the rat hippocampus. Neurobiology of Disease. 8: 1046-56. PMID 11741400 DOI: 10.1006/nbdi.2001.0427  0.327
2001 Rohn TT, Head E, Nesse WH, Cotman CW, Cribbs DH. Activation of caspase-8 in the Alzheimer's disease brain. Neurobiology of Disease. 8: 1006-16. PMID 11741396 DOI: 10.1006/Nbdi.2001.0449  0.637
2001 Head E, Garzon-Rodriguez W, Johnson JK, Lott IT, Cotman CW, Glabe C. Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome. Neurobiology of Disease. 8: 792-806. PMID 11592849 DOI: 10.1006/nbdi.2001.0431  0.633
2001 Stoltzner SE, Berchtold NC, Cotman CW, Pike CJ. Estrogen regulates bcl-x expression in rat hippocampus. Neuroreport. 12: 2797-800. PMID 11588579 DOI: 10.1097/00001756-200109170-00009  0.673
2001 Nichol KE, Kim R, Cotman CW. Bcl-2 family protein behavior in frontotemporal dementia implies vascular involvement. Neurology. 56: S35-40. PMID 11402149 DOI: 10.1212/Wnl.56.Suppl_4.S35  0.329
2001 Su JH, Zhao M, Anderson AJ, Srinivasan A, Cotman CW. Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology. Brain Research. 898: 350-7. PMID 11306022 DOI: 10.1016/S0006-8993(01)02018-2  0.655
2001 Head E, Azizeh BY, Lott IT, Tenner AJ, Cotman CW, Cribbs DH. Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome. Neurobiology of Disease. 8: 252-65. PMID 11300721 DOI: 10.1006/Nbdi.2000.0380  0.657
2001 Tong L, Thornton PL, Balazs R, Cotman CW. Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised. The Journal of Biological Chemistry. 276: 17301-6. PMID 11278679 DOI: 10.1074/jbc.M010450200  0.377
2001 Martin JA, Craft DK, Su JH, Kim RC, Cotman CW. Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion. Neurobiology of Aging. 22: 195-207. PMID 11182469 DOI: 10.1016/S0197-4580(00)00231-1  0.552
2001 Rohn TT, Head E, Su JH, Anderson AJ, Bahr BA, Cotman CW, Cribbs DH. Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease. The American Journal of Pathology. 158: 189-98. PMID 11141492 DOI: 10.1016/S0002-9440(10)63957-0  0.752
2000 Cotman CW, Anderson AJ. The brain's microenvironment, early functional loss, and the conversion to Alzheimer's disease. Annals of the New York Academy of Sciences. 924: 112-6. PMID 11193787 DOI: 10.1111/J.1749-6632.2000.Tb05569.X  0.642
2000 Torp R, Head E, Cotman CW. Ultrastructural analyses of beta-amyloid in the aged dog brain: neuronal beta-amyloid is localized to the plasma membrane. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 801-10. PMID 11191714 DOI: 10.1016/S0278-5846(00)00107-X  0.625
2000 Head E, Thornton PL, Tong L, Cotman CW. Initiation and propagation of molecular cascades in human brain aging: insight from the canine model to promote successful aging. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 777-86. PMID 11191712 DOI: 10.1016/S0278-5846(00)00105-6  0.653
2000 Callahan H, Ikeda-Douglas C, Head E, Cotman CW, Milgram NW. Development of a protocol for studying object recognition memory in the dog. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 693-707. PMID 11191709 DOI: 10.1016/S0278-5846(00)00102-0  0.573
2000 Head E, Cotman CW, Milgram NW. Canine cognition, aging and neuropathology. Introduction. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 671-3. PMID 11191707 DOI: 10.1016/S0278-5846(00)00100-7  0.606
2000 Dick MB, Hsieh S, Dick-Muehlke C, Davis DS, Cotman CW. The variability of practice hypothesis in motor learning: does it apply to Alzheimer's disease? Brain and Cognition. 44: 470-89. PMID 11104538 DOI: 10.1006/brcg.2000.1206  0.708
2000 Russo-Neustadt AA, Beard RC, Huang YM, Cotman CW. Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus. Neuroscience. 101: 305-12. PMID 11074154 DOI: 10.1016/S0306-4522(00)00349-3  0.319
2000 Johnson JK, Head E, Kim R, Starr A, Cotman CW. Topography, histology, and seminology in dementia Archives of Neurology. 57: 899-900. PMID 10867791 DOI: 10.1001/Archneur.57.6.899  0.593
2000 Cribbs DH, Azizeh BY, Cotman CW, LaFerla FM. Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide. Biochemistry. 39: 5988-94. PMID 10821670 DOI: 10.1021/bi000029f  0.525
2000 Rohn TT, Ivins KJ, Bahr BA, Cotman CW, Cribbs DH. A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis. Journal of Neurochemistry. 74: 2331-42. PMID 10820193 DOI: 10.1046/j.1471-4159.2000.0742331.x  0.325
2000 Head E, McCleary R, Hahn FF, Milgram NW, Cotman CW. Region-specific age at onset of beta-amyloid in dogs. Neurobiology of Aging. 21: 89-96. PMID 10794853 DOI: 10.1016/S0197-4580(00)00093-2  0.63
2000 Azizeh BY, Head E, Ibrahim MA, Torp R, Tenner AJ, Kim RC, Lott IT, Cotman CW. Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs. Experimental Neurology. 163: 111-22. PMID 10785449 DOI: 10.1006/Exnr.2000.7359  0.647
2000 Su JH, Nichol KE, Sitch T, Sheu P, Chubb C, Miller BL, Tomaselli KJ, Kim RC, Cotman CW. DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia. Experimental Neurology. 163: 9-19. PMID 10785439 DOI: 10.1006/Exnr.2000.7340  0.351
2000 Torp R, Head E, Milgram NW, Hahn F, Ottersen OP, Cotman CW. Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains. Neuroscience. 96: 495-506. PMID 10717430 DOI: 10.1016/S0306-4522(99)00568-0  0.622
2000 Adams B, Chan A, Callahan H, Siwak C, Tapp D, Ikeda-Douglas C, Atkinson P, Head E, Cotman CW, Milgram NW. Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog. Behavioural Brain Research. 108: 47-56. PMID 10680756 DOI: 10.1016/S0166-4328(99)00132-1  0.609
2000 Torp R, Azizeh BY, Head E, Cotman C. 5. Molecular dating of senile plaques in the brains of individuals with Down syndrome. Acta Neurologica Scandinavica. 102: 5-52. DOI: 10.1034/j.1600-0404.2000.00202-31.x  0.596
2000 Head E, Azizeh BY, Wong SM, Lott IT, Tenner AJ, Cotman CW, Cribbs DH. C1Q and inflammation in Down syndrome pathogenesis Neurobiology of Aging. 21: 12. DOI: 10.1016/S0197-4580(00)82731-1  0.546
2000 Cotman CW, Anderson AJ, Cribbs DH. β-amyloid: An inert deposit comes alive Neurobiology of Aging. 21: 134. DOI: 10.1016/S0197-4580(00)82401-X  0.577
1999 Ivins KJ, Thornton PL, Rohn TT, Cotman CW. Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8. Neurobiology of Disease. 6: 440-9. PMID 10527810 DOI: 10.1006/nbdi.1999.0268  0.303
1999 Johnson JK, Head E, Kim R, Starr A, Cotman CW. Clinical and pathological evidence for a frontal variant of Alzheimer disease. Archives of Neurology. 56: 1233-9. PMID 10520939 DOI: 10.1001/Archneur.56.10.1233  0.634
1999 Kim D, Su J, Cotman CW. Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment. Brain Research. 839: 253-62. PMID 10519048 DOI: 10.1016/S0006-8993(99)01724-2  0.335
1999 Russo-Neustadt A, Beard RC, Cotman CW. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 679-82. PMID 10516964 DOI: 10.1016/S0893-133X(99)00059-7  0.314
1999 Berchtold NC, Oliff HS, Isackson P, Cotman CW. Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript. Brain Research. Molecular Brain Research. 71: 11-22. PMID 10407182 DOI: 10.1016/S0169-328X(99)00137-0  0.677
1999 Fonseca MI, Head E, Velazquez P, Cotman CW, Tenner AJ. The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age. Experimental Neurology. 157: 277-88. PMID 10364440 DOI: 10.1006/Exnr.1999.7058  0.644
1999 Milgram NW, Adams B, Callahan H, Head E, Mackay B, Thirlwell C, Cotman CW. Landmark discrimination learning in the dog. Learning & Memory (Cold Spring Harbor, N.Y.). 6: 54-61. PMID 10355524 DOI: 10.1101/Lm.6.1.54  0.579
1999 Leissring MA, Paul BA, Parker I, Cotman CW, LaFerla FM. Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes. Journal of Neurochemistry. 72: 1061-8. PMID 10037477 DOI: 10.1046/J.1471-4159.1999.0721061.X  0.513
1998 Ivins KJ, Bui ET, Cotman CW. Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis. Neurobiology of Disease. 5: 365-78. PMID 10069579 DOI: 10.1006/nbdi.1998.0228  0.317
1998 Su MY, Head E, Brooks WM, Wang Z, Muggenburg BA, Adam GE, Sutherland R, Cotman CW, Nalcioglu O. Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging. Neurobiology of Aging. 19: 479-85. PMID 9880050 DOI: 10.1016/S0197-4580(98)00081-5  0.621
1998 Head E, Callahan H, Muggenburg BA, Cotman CW, Milgram NW. Visual-discrimination learning ability and beta-amyloid accumulation in the dog. Neurobiology of Aging. 19: 415-25. PMID 9880044 DOI: 10.1016/S0197-4580(98)00084-0  0.622
1998 Johnson JK, Cotman CW, Tasaki CS, Shaw GL. Enhancement of spatial-temporal reasoning after a Mozart listening condition in Alzheimer's disease: a case study. Neurological Research. 20: 666-72. PMID 9864729 DOI: 10.1080/01616412.1998.11740582  0.315
1998 Eckert A, Cotman CW, Zerfass R, Hennerici M, Müller WE. Lymphocytes as cell model to study apoptosis in Alzheimer's disease: vulnerability to programmed cell death appears to be altered. Journal of Neural Transmission. Supplementum. 54: 259-67. PMID 9850934 DOI: 10.1007/978-3-7091-7508-8_25  0.349
1998 Torp R, Su JH, Deng G, Cotman CW. GADD45 is induced in Alzheimer's disease, and protects against apoptosis in vitro. Neurobiology of Disease. 5: 245-52. PMID 9848094 DOI: 10.1006/nbdi.1998.0201  0.314
1998 Su JH, Cummings BJ, Cotman CW. Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites. Acta Neuropathologica. 96: 463-71. PMID 9829809 DOI: 10.1007/S004010050920  0.369
1998 Oliff HS, Berchtold NC, Isackson P, Cotman CW. Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus. Brain Research. Molecular Brain Research. 61: 147-53. PMID 9795193 DOI: 10.1016/S0169-328X(98)00222-8  0.694
1998 Kesslak JP, So V, Choi J, Cotman CW, Gomez-Pinilla F. Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behavioral Neuroscience. 112: 1012-9. PMID 9733207 DOI: 10.1037/0735-7044.112.4.1012  0.335
1998 Russo-Neustadt A, Zomorodian TJ, Cotman CW. Preserved cerebellar tyrosine hydroxylase-immunoreactive neuronal fibers in a behaviorally aggressive subgroup of Alzheimer's disease patients. Neuroscience. 87: 55-61. PMID 9722141 DOI: 10.1016/S0306-4522(98)00134-1  0.334
1998 Eckert A, Cotman CW, Zerfass R, Hennerici M, Müller WE. Enhanced vulnerability to apoptotic cell death in sporadic Alzheimer's disease. Neuroreport. 9: 2443-6. PMID 9721911 DOI: 10.1097/00001756-199808030-00003  0.345
1998 Cotman CW, Hailer NP, Pfister KK, Soltesz I, Schachner M. Cell adhesion molecules in neural plasticity and pathology: similar mechanisms, distinct organizations? Progress in Neurobiology. 55: 659-69. PMID 9670224 DOI: 10.1016/S0301-0082(98)00025-2  0.367
1998 Johnson JK, McCleary R, Oshita MH, Cotman CW. Initiation and propagation stages of beta-amyloid are associated with distinctive apolipoprotein E, age, and gender profiles. Brain Research. 798: 18-24. PMID 9666062 DOI: 10.1016/S0006-8993(98)00363-1  0.304
1998 Berchtold NC, Cotman CW. Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s. Neurobiology of Aging. 19: 173-89. PMID 9661992 DOI: 10.1016/S0197-4580(98)00052-9  0.705
1998 Cotman CW. Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease. Neurobiology of Aging. 19: S29-32. PMID 9562464 DOI: 10.1016/S0197-4580(98)00042-6  0.322
1998 Cotman CW, Berchtold NC. Plasticity and growth factors injury response Mental Retardation and Developmental Disabilities Research Reviews. 4: 223-230. DOI: 10.1002/(Sici)1098-2779(1998)4:3<223::Aid-Mrdd10>3.0.Co;2-X  0.686
1997 Su JH, Deng G, Cotman CW. Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain. Brain Research. 774: 193-9. PMID 9452208 DOI: 10.1016/S0006-8993(97)81703-9  0.332
1997 Satou T, Cummings BJ, Head E, Nielson KA, Hahn FF, Milgram NW, Velazquez P, Cribbs DH, Tenner AJ, Cotman CW. The progression of beta-amyloid deposition in the frontal cortex of the aged canine. Brain Research. 774: 35-43. PMID 9452189 DOI: 10.1016/S0006-8993(97)81684-8  0.725
1997 Su JH, Deng G, Cotman CW. Transneuronal degeneration in the spread of Alzheimer's disease pathology: immunohistochemical evidence for the transmission of tau hyperphosphorylation. Neurobiology of Disease. 4: 365-75. PMID 9440125 DOI: 10.1006/nbdi.1997.0164  0.368
1997 Major DE, Kesslak JP, Cotman CW, Finch CE, Day JR. Life-long dietary restriction attenuates age-related increases in hippocampal glial fibrillary acidic protein mRNA. Neurobiology of Aging. 18: 523-6. PMID 9390779 DOI: 10.1016/S0197-4580(97)00102-4  0.336
1997 Head E, Callahan H, Cummings BJ, Cotman CW, Ruehl WW, Muggenberg BA, Milgram NW. Open field activity and human interaction as a function of age and breed in dogs. Physiology & Behavior. 62: 963-71. PMID 9333188 DOI: 10.1016/S0031-9384(97)00198-4  0.604
1997 de Figueiredo RJ, Oten R, Su J, Cotman CW. Amyloid deposition in cerebrovascular angiopathy. Annals of the New York Academy of Sciences. 826: 463-71. PMID 9329725 DOI: 10.1111/J.1749-6632.1997.Tb48505.X  0.333
1997 Ulas J, Cotman CW. Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience. 79: 973-82. PMID 9219960 DOI: 10.1016/S0306-4522(97)00023-7  0.366
1997 Russo-Neustadt A, Cotman CW. Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5573-80. PMID 9204938 DOI: 10.1523/Jneurosci.17-14-05573.1997  0.334
1997 Su JH, Deng G, Cotman CW. Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology. Journal of Neuropathology and Experimental Neurology. 56: 86-93. PMID 8990132 DOI: 10.1097/00005072-199701000-00009  0.366
1996 Cummings BJ, Pike CJ, Shankle R, Cotman CW. Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiology of Aging. 17: 921-33. PMID 9363804 DOI: 10.1016/S0197-4580(96)00170-4  0.362
1996 Nielson KA, Cummings BJ, Cotman CW. Constructional apraxia in Alzheimer's disease correlates with neuritic neuropathology in occipital cortex. Brain Research. 741: 284-93. PMID 9001734 DOI: 10.1016/S0006-8993(96)00983-3  0.649
1996 Su JH, Cummings BJ, Cotman CW. Plaque biogenesis in brain aging and Alzheimer's disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments. Brain Research. 739: 79-87. PMID 8955927 DOI: 10.1016/S0006-8993(96)00811-6  0.378
1996 Cotman CW, Su JH. Mechanisms of neuronal death in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 6: 493-506. PMID 8944319 DOI: 10.1111/J.1750-3639.1996.Tb00878.X  0.327
1996 Deng G, Su JH, Cotman CW. Gene expression of Alzheimer-associated presenilin-2 in the frontal cortex of Alzheimer and aged control brain. Febs Letters. 394: 17-20. PMID 8925918 DOI: 10.1016/0014-5793(96)00922-2  0.361
1996 Cribbs DH, Kreng VM, Anderson AJ, Cotman CW. Cross-linking of concanavalin A receptors on cortical neurons induces programmed cell death. Neuroscience. 75: 173-85. PMID 8923532 DOI: 10.1016/0306-4522(96)80001-P  0.586
1996 Cribbs DH, Chen LS, Cotman CW, LaFerla FM. Injury induces presenilin-1 gene expression in mouse brain. Neuroreport. 7: 1773-6. PMID 8905662 DOI: 10.1097/00001756-199607290-00016  0.539
1996 Cotman CW, Tenner AJ, Cummings BJ. beta-Amyloid converts an acute phase injury response to chronic injury responses. Neurobiology of Aging. 17: 723-31. PMID 8892345 DOI: 10.1016/0197-4580(96)00117-0  0.31
1996 Pike CJ, Balázs R, Cotman CW. Attenuation of beta-amyloid neurotoxicity in vitro by potassium-induced depolarization. Journal of Neurochemistry. 67: 1774-7. PMID 8858966 DOI: 10.1046/J.1471-4159.1996.67041774.X  0.305
1996 Neeper SA, Gómez-Pinilla F, Choi J, Cotman CW. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Research. 726: 49-56. PMID 8836544 DOI: 10.1016/0006-8993(96)00273-9  0.329
1996 Cummings BJ, Satou T, Head E, Milgram NW, Cole GM, Savage MJ, Podlisny MB, Selkoe DJ, Siman R, Greenberg BD, Cotman CW. Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs. Neurobiology of Aging. 17: 653-9. PMID 8832640 DOI: 10.1016/0197-4580(96)00062-0  0.595
1996 Dick MB, Shankle RW, Beth RE, Dick-Muehlke C, Cotman CW, Kean ML. Acquisition and long-term retention of a gross motor skill in Alzheimer's disease patients under constant and varied practice conditions. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences. 51: P103-11. PMID 8785686 DOI: 10.1093/Geronb/51B.2.P103  0.709
1996 Anderson AJ, Su JH, Cotman CW. DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1710-9. PMID 8774439 DOI: 10.1523/Jneurosci.16-05-01710.1996  0.635
1996 Cummings BJ, Head E, Ruehl W, Milgram NW, Cotman CW. The canine as an animal model of human aging and dementia. Neurobiology of Aging. 17: 259-68. PMID 8744407 DOI: 10.1016/0197-4580(95)02060-8  0.656
1996 Su JH, Satou T, Anderson AJ, Cotman CW. Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease. Neuroreport. 7: 437-40. PMID 8730800 DOI: 10.1097/00001756-199601310-00015  0.616
1996 Nielson KA, Nolan JH, Berchtold NC, Sandman CA, Mulnard RA, Cotman CW. Apolipoprotein-E genotyping of diabetic dementia patients: is diabetes rare in Alzheimer's disease? Journal of the American Geriatrics Society. 44: 897-904. PMID 8708297 DOI: 10.1111/J.1532-5415.1996.Tb01857.X  0.777
1996 Cummings BJ, Head E, Afagh AJ, Milgram NW, Cotman CW. Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine. Neurobiology of Learning and Memory. 66: 11-23. PMID 8661247 DOI: 10.1006/Nlme.1996.0039  0.639
1996 Pike CJ, Ramezan-Arab N, Miller S, Cotman CW. beta-Amyloid increases enzyme activity and protein levels of glutamine synthetase in cultured astrocytes. Experimental Neurology. 139: 167-71. PMID 8635563 DOI: 10.1006/Exnr.1996.0091  0.302
1996 Pike CJ, Vaughan PJ, Cunningham DD, Cotman CW. Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. Journal of Neurochemistry. 66: 1374-82. PMID 8627288 DOI: 10.1046/J.1471-4159.1996.66041374.X  0.309
1996 Afagh A, Cummings BJ, Cribbs DH, Cotman CW, Tenner AJ. Localization and cell association of C1q in Alzheimer's disease brain. Experimental Neurology. 138: 22-32. PMID 8593893 DOI: 10.1006/Exnr.1996.0043  0.374
1996 Anderson A, Sue J, Satou T, Cotman C. 732 Ref-1 immunoreactivity in Alzheimer's disease Neurobiology of Aging. 17: S182. DOI: 10.1016/S0197-4580(96)80734-2  0.612
1996 Cummings B, Pike C, Cotman C. 722 Multiple neuropathological variables are correlated with the level of cognitive impairment in Alzheimer's disease Neurobiology of Aging. 17: S179. DOI: 10.1016/S0197-4580(96)80724-X  0.314
1995 Dick MB, Nielson KA, Beth RE, Shankle WR, Cotman CW. Acquisition and long-term retention of a fine motor skill in Alzheimer's disease. Brain and Cognition. 29: 294-306. PMID 8838387 DOI: 10.1006/Brcg.1995.1283  0.774
1995 Shankle WR, Nielson KA, Cotman CW. Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients. Alzheimer Disease and Associated Disorders. 9: 233-7. PMID 8749613 DOI: 10.1097/00002093-199500940-00010  0.562
1995 Woods AG, Cribbs DH, Whittemore ER, Cotman CW. Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate beta-amyloid(25-35) induced neurodegeneration in cultured hippocampal neurons. Brain Research. 697: 53-62. PMID 8593595 DOI: 10.1016/0006-8993(95)00775-L  0.309
1995 Satou T, Cummings BJ, Cotman CW. Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity. Brain Research. 697: 35-43. PMID 8593592 DOI: 10.1016/0006-8993(95)00748-F  0.373
1995 Ruehl WW, Bruyette DS, DePaoli A, Cotman CW, Head E, Milgram NW, Cummings BJ. Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy. Progress in Brain Research. 106: 217-25. PMID 8584657 DOI: 10.1016/S0079-6123(08)61218-2  0.632
1995 Head E, Mehta R, Hartley J, Kameka M, Cummings BJ, Cotman CW, Ruehl WW, Milgram NW. Spatial learning and memory as a function of age in the dog. Behavioral Neuroscience. 109: 851-8. PMID 8554710 DOI: 10.1037//0735-7044.109.5.851  0.606
1995 Choi BH, Kim RC, Vaughan PJ, Lau A, Van Nostrand WE, Cotman CW, Cunningham DD. Decreases in protease nexins in Alzheimer's disease brain. Neurobiology of Aging. 16: 557-62. PMID 8544905 DOI: 10.1016/0197-4580(95)00060-R  0.389
1995 Pike CJ, Cummings BJ, Cotman CW. Early association of reactive astrocytes with senile plaques in Alzheimer's disease. Experimental Neurology. 132: 172-9. PMID 7789457 DOI: 10.1016/0014-4886(95)90022-5  0.379
1995 deFigueiredo RJ, Shankle WR, Maccato A, Dick MB, Mundkur P, Mena I, Cotman CW. Neural-network-based classification of cognitively normal, demented, Alzheimer disease and vascular dementia from single photon emission with computed tomography image data from brain. Proceedings of the National Academy of Sciences of the United States of America. 92: 5530-4. PMID 7777543 DOI: 10.1073/Pnas.92.12.5530  0.702
1995 Vaughan PJ, Pike CJ, Cotman CW, Cunningham DD. Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5389-401. PMID 7623161 DOI: 10.1523/Jneurosci.15-07-05389.1995  0.306
1995 Miller S, Kesslak JP, Romano C, Cotman CW. Roles of metabotropic glutamate receptors in brain plasticity and pathology. Annals of the New York Academy of Sciences. 757: 460-74. PMID 7611703 DOI: 10.1111/J.1749-6632.1995.Tb17506.X  0.312
1995 Cotman CW, Anderson AJ. A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Molecular Neurobiology. 10: 19-45. PMID 7598831 DOI: 10.1007/Bf02740836  0.612
1995 Anderson AJ, Pike CJ, Cotman CW. Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis. Journal of Neurochemistry. 65: 1487-98. PMID 7561842 DOI: 10.1046/J.1471-4159.1995.65041487.X  0.606
1995 Korotzer AR, Watt J, Cribbs D, Tenner AJ, Burdick D, Glabe C, Cotman CW. Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia. Experimental Neurology. 134: 214-21. PMID 7556541 DOI: 10.1006/Exnr.1995.1051  0.343
1995 Cummings BJ, Cotman CW. Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity. Lancet. 346: 1524-8. PMID 7491048 DOI: 10.1016/S0140-6736(95)92053-6  0.357
1994 Anderson AJ, Cummings BJ, Cotman CW. Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology. Experimental Neurology. 125: 286-95. PMID 8313943 DOI: 10.1006/Exnr.1994.1031  0.647
1994 Su JH, Cummings BJ, Cotman CW. Subpopulations of dystrophic neurites [correction of neuritis] in Alzheimer's brain with distinct immunocytochemical and argentophilic characteristics. Brain Research. 637: 37-44. PMID 8180819 DOI: 10.1016/0006-8993(94)91214-9  0.304
1994 Pike CJ, Cummings BJ, Monzavi R, Cotman CW. Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease. Neuroscience. 63: 517-31. PMID 7891862 DOI: 10.1016/0306-4522(94)90547-9  0.347
1994 Cotman CW, Whittemore ER, Watt JA, Anderson AJ, Loo DT. Possible role of apoptosis in Alzheimer's disease. Annals of the New York Academy of Sciences. 747: 36-49. PMID 7847684 DOI: 10.1111/J.1749-6632.1994.Tb44400.X  0.606
1994 Smyth MD, Cribbs DH, Tenner AJ, Shankle WR, Dick M, Kesslak JP, Cotman CW. Decreased levels of C1q in cerebrospinal fluid of living Alzheimer patients correlate with disease state. Neurobiology of Aging. 15: 609-14. PMID 7824052 DOI: 10.1016/0197-4580(94)00055-7  0.332
1994 Vaughan PJ, Su J, Cotman CW, Cunningham DD. Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Research. 668: 160-70. PMID 7704602 DOI: 10.1016/0006-8993(94)90521-5  0.37
1994 Su JH, Anderson AJ, Cummings BJ, Cotman CW. Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport. 5: 2529-33. PMID 7696596 DOI: 10.1097/00001756-199412000-00031  0.641
1994 Su JH, Cummings BJ, Cotman CW. Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites. Neuroreport. 5: 2358-62. PMID 7533559 DOI: 10.1097/00001756-199411000-00037  0.318
1993 Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ, Cotman CW. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proceedings of the National Academy of Sciences of the United States of America. 90: 7951-5. PMID 8367446 DOI: 10.1073/Pnas.90.17.7951  0.318
1993 Cummings BJ, Su JH, Cotman CW, White R, Russell MJ. Beta-amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease. Neurobiology of Aging. 14: 547-60. PMID 8295657 DOI: 10.1016/0197-4580(93)90038-D  0.367
1993 Cummings BJ, Su JH, Cotman CW. Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease. Experimental Neurology. 124: 315-25. PMID 8287930 DOI: 10.1006/exnr.1993.1202  0.401
1993 Wagner SL, Van Nostrand WE, Lau AL, Farrow JS, Suzuki M, Bartus RT, Schuppek R, Nguyen A, Cotman CW, Cunningham DD. Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates. Brain Research. 626: 90-8. PMID 8281456 DOI: 10.1016/0006-8993(93)90567-7  0.34
1993 Su JH, Cummings BJ, Cotman CW. Identification and distribution of axonal dystrophic neurites in Alzheimer's disease. Brain Research. 625: 228-37. PMID 8275305 DOI: 10.1016/0006-8993(93)91063-X  0.308
1993 Pike CJ, Cotman CW. Cultured GABA-immunoreactive neurons are resistant to toxicity induced by beta-amyloid. Neuroscience. 56: 269-74. PMID 8247260 DOI: 10.1016/0306-4522(93)90331-9  0.333
1993 Su JH, Cummings BJ, Cotman CW. Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease. Neuroscience. 51: 801-13. PMID 1488123 DOI: 10.1016/0306-4522(92)90521-3  0.379
1992 Geddes JW, Cotman CW. Plasticity in Alzheimer's disease: too much or not enough? Neurobiology of Aging. 12: 330-3; discussion 35. PMID 1961362 DOI: 10.1016/0197-4580(91)90011-8  0.364
1992 Cotman CW, Gómez-Pinilla F. Basic fibroblast growth factor in the mature brain and its possible role in Alzheimer's disease. Annals of the New York Academy of Sciences. 638: 221-31. PMID 1785803 DOI: 10.1111/j.1749-6632.1991.tb49033.x  0.323
1992 Araujo DM, Cotman CW. Beta-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease. Brain Research. 569: 141-5. PMID 1611474 DOI: 10.1016/0006-8993(92)90380-R  0.31
1992 Taube JS, Kesslak JP, Cotman CW. Lesions of the rat postsubiculum impair performance on spatial tasks. Behavioral and Neural Biology. 57: 131-43. PMID 1586352 DOI: 10.1016/0163-1047(92)90629-I  0.578
1992 Van Nosthand WE, Wagner SL, Rodman Shankle W, Farrow JS, Dick M, Rozemuller JM, Kuiper MA, Wolters EC, Zimmerman J, Cotman CW, Cunningham DD. Decreased levels of soluble amyloid β-protein precursor in cerebrospinal fluid of live Alzheimer disease patients Proceedings of the National Academy of Sciences of the United States of America. 89: 2551-2555. PMID 1557359 DOI: 10.1073/PNAS.89.7.2551  0.728
1992 Cotman CW, Pike CJ, Copani A. β-Amyloid neurotoxicity: A discussion of in vitro findings Neurobiology of Aging. 13: 587-590. PMID 1461347 DOI: 10.1016/0197-4580(92)90060-B  0.331
1992 Kammesheidt A, Boyce FM, Spanoyannis AF, Cummings BJ, Ortegon M, Cotman C, Vaught JL, Neve RL. Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain Proceedings of the National Academy of Sciences of the United States of America. 89: 10857-10861. PMID 1438289 DOI: 10.1073/Pnas.89.22.10857  0.345
1992 Pike CJ, Cummings BJ, Cotman CW. µ-Amyloid induces neuritic dystrophy in vitro: Similarities with alzherimer pathology Neuroreport. 3: 769-772. PMID 1421135 DOI: 10.1097/00001756-199209000-00012  0.356
1992 Ułas J, Brunner LC, Geddes JW, Choe W, Cotman CW. N-methyl-d-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease Neuroscience. 49: 45-61. PMID 1407551 DOI: 10.1016/0306-4522(92)90075-D  0.311
1992 Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW. Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience. 48: 763-77. PMID 1378573 DOI: 10.1016/0306-4522(92)90265-4  0.367
1992 Geddes JW, Ułas J, Brunner LC, Choe W, Cotman CW. Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with alzheimer's disease: Non-N-methyl-d-aspartate receptors Neuroscience. 50: 23-34. PMID 1328933 DOI: 10.1016/0306-4522(92)90379-G  0.313
1992 Clark AS, Magnusson KR, Cotman CW. In vitro autoradiography of hippocampal excitatory amino acid binding in aged Fischer 344 rats: relationship to performance on the Morris water maze. Behavioral Neuroscience. 106: 324-35. PMID 1317185 DOI: 10.1037//0735-7044.106.2.324  0.306
1992 Gomez-Pinilla F, Lee J, Cotman C. Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesion and fimbria-fornix transection The Journal of Neuroscience. 12: 345-355. DOI: 10.1523/Jneurosci.12-01-00345.1992  0.318
1991 Peterson C, Vanderklish P, Seubert P, Cotman C, Lynch G. Increased spectrin proteolysis in fibroblasts from aged and Alzheimer donors. Neuroscience Letters. 121: 239-43. PMID 2020380 DOI: 10.1016/0304-3940(91)90694-O  0.33
1991 Vijayan VK, Geddes JW, Anderson KJ, Chang-Chui H, Ellis WG, Cotman CW. Astrocyte hypertrophy in the Alzheimer's disease hippocampal formation. Experimental Neurology. 112: 72-8. PMID 2013308 DOI: 10.1016/0014-4886(91)90115-S  0.352
1991 Patrick Kesslak J, Nalcioglu O, Cotman CW. Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in alzheimer’s disease Neurology. 41: 51-54. PMID 1985296 DOI: 10.1212/WNL.41.1.51  0.334
1991 Cotman CW, Geddes JW, Ulas J, Klein M. Plasticity of excitatory amino acid receptors: implications for aging and Alzheimer's disease. Progress in Brain Research. 86: 55-61. PMID 1965056 DOI: 10.1016/S0079-6123(08)63166-0  0.355
1991 Van Nostrand WE, Farrow JS, Wagner SL, Bhasin R, Goldgaber D, Cotman CW, Cunningham DD. The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proceedings of the National Academy of Sciences of the United States of America. 88: 10302-6. PMID 1946448 DOI: 10.1073/Pnas.88.22.10302  0.333
1991 Copani A, Koh J, Cotman CW. β-amyloid increases neuronal susceptibility to injury by glucose deprivation Neuroreport. 2: 763-765. PMID 1793819 DOI: 10.1097/00001756-199112000-00008  0.302
1991 Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Research. 563: 311-4. PMID 1786545 DOI: 10.1016/0006-8993(91)91553-D  0.301
1991 Gómez-Pinilla F, Cummings BJ, Cotman CW. Induction of basic fibroblast growth factor in Alzheimer's disease pathology. Neuroreport. 1: 211-4. PMID 1717039 DOI: 10.1097/00001756-199011000-00009  0.386
1990 Cotman C, Monaghan D. Multiple excitatory amino acid receptor regulation of intracellular Ca2+. Implications for aging and Alzheimer's disease. Annals of the New York Academy of Sciences. 568: 138-48. PMID 2560895 DOI: 10.1111/j.1749-6632.1989.tb12501.x  0.306
1990 Peterson C, Cotman CW. Decreased survival of hippocampal neurons in medium conditioned by fibroblasts from aged and Alzheimer donors. Brain Research. 515: 39-44. PMID 2357575 DOI: 10.1016/0006-8993(90)90573-T  0.343
1990 Geddes JW, Wong J, Choi BH, Kim RC, Cotman CW, Miller FD. Increased expression of the embryonic form of a developmentally regulated mRNA in Alzheimer's disease. Neuroscience Letters. 109: 54-61. PMID 2314641 DOI: 10.1016/0304-3940(90)90537-J  0.359
1990 Koh Jy, Yang LL, Cotman CW. β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage Brain Research. 533: 315-320. PMID 2289145 DOI: 10.1016/0006-8993(90)91355-K  0.352
1990 Cotman CW, Geddes JW, Kahle JS. Axon sprouting in the rodent and Alzheimer's disease brain: a reactivation of developmental mechanisms? Progress in Brain Research. 83: 427-34. PMID 2203106 DOI: 10.1016/S0079-6123(08)61266-2  0.344
1990 Whitson JS, Glabe CG, Shintani E, Abcar A, Cotman CW. Beta-amyloid protein promotes neuritic branching in hippocampal cultures. Neuroscience Letters. 110: 319-24. PMID 2183090 DOI: 10.1016/0304-3940(90)90867-9  0.306
1990 Geddes JW, Wilson MC, Miller FD, Cotman CW. Molecular markers of reactive plasticity. Advances in Experimental Medicine and Biology. 268: 425-32. PMID 2075860 DOI: 10.1007/978-1-4684-5769-8_47  0.344
1990 Geddes JW, Hess EJ, Hart RA, Kesslak JP, Cotman CW, Wilson MC. Lesions of hippocampal circuitry define synaptosomal-associated protein-25 (SNAP-25) as a novel presynaptic marker. Neuroscience. 38: 515-25. PMID 1702194 DOI: 10.1016/0306-4522(90)90047-8  0.318
1990 Smith JR, Flanigin HF, King DW, Aceves J, Pan DH, Lee L, Huang C, Wong T, Heikkinen ER, Rönty HS, Tolonen U, Pyhtinen J, Gogolitsin YL, Nechaev VB, Hitchcock ER, ... ... Cotman C, et al. Subject Index Vol. 54+55, 1990 Stereotactic and Functional Neurosurgery. 54: 561-564. DOI: 10.1159/000100274  0.363
1989 Whitson JS, Selkoe DJ, Cotman CW. Amyloid β protein enhances the survival of hippocampal neurons in vitro Science. 243: 1488-1490. PMID 2928783 DOI: 10.1126/SCIENCE.2928783  0.327
1989 Wagner SL, Geddes JW, Cotman CW, Lau AL, Gurwitz D, Isackson PJ, Cunningham DD. Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 86: 8284-8. PMID 2813392 DOI: 10.1073/Pnas.86.21.8284  0.364
1989 Geddes JW, Cotman CW. Plasticity, pathology, and Alzheimer's disease. Neurobiology of Aging. 10: 571-3; discussion 58. PMID 2812229 DOI: 10.1016/0197-4580(89)90131-0  0.337
1989 Gómez-Pinilla F, Cotman CW, Nieto-Sampedro M. NGF receptor immunoreactivity in aged rat brain. Brain Research. 479: 255-62. PMID 2538208 DOI: 10.1016/0006-8993(89)91626-0  0.333
1989 Van Nostrand WE, Wagner SL, Suzuki M, Choi BH, Farrow JS, Geddes JW, Cotman CW, Cunningham DD. Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature. 341: 546-9. PMID 2507928 DOI: 10.1038/341546A0  0.326
1989 Cotman CW, Monaghan DT, Geddes JW. N‐methyl‐D‐aspartate receptors, synaptic plasticity, and Alzheimer's disease Drug Development Research. 17: 331-338. DOI: 10.1002/ddr.430170408  0.302
1988 Gibbs RB, Needels DL, Yu J, Cotman CW. Effects of entorhinal lesions on trophic activities present in rat entorhinal cortex and hippocampus as studied using primary cultures of entorhinal and septal tissues. Journal of Neuroscience Research. 18: 274-88. PMID 3694710 DOI: 10.1002/JNR.490180203  0.305
1988 Anderson KJ, Dam D, Lee S, Cotman CW. Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo Nature. 332: 360-361. PMID 3352734 DOI: 10.1038/332360A0  0.308
1987 Geddes JW, Chang-Chui H, Cooper SM, Lott IT, Cotman CW. Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease. Brain Research. 399: 156-61. PMID 2879613 DOI: 10.1016/0006-8993(86)90611-6  0.323
1986 Geddes JW, Anderson KJ, Cotman CW. Senile plaques as aberrant sprout-stimulating structures Experimental Neurology. 94: 767-776. PMID 3780919 DOI: 10.1016/0014-4886(86)90254-2  0.341
1986 Needels DL, Nieto-Sampedro M, Cotman CW. Induction of a neurite-promoting factor in rat brain following injury or deafferentation. Neuroscience. 18: 517-26. PMID 3748376 DOI: 10.1016/0306-4522(86)90055-2  0.316
1986 Anderson KJ, Monaghan DT, Cangro CB, Namboodiri MAA, Neale JH, Cotman CW. Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain Neuroscience Letters. 72: 14-20. PMID 3543748 DOI: 10.1016/0304-3940(86)90610-5  0.302
1986 Anderson KJ, Gibbs RB, Salvaterra PM, Cotman CW. Ultrastructural characterization of identified cholinergic neurons transplanted to the hippocampal formation of the rat. The Journal of Comparative Neurology. 249: 279-92. PMID 3525619 DOI: 10.1002/cne.902490211  0.605
1986 Geddes JW, Cotman CW. Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease. Neuroscience Research. 3: 672-8. PMID 2877425 DOI: 10.1016/0168-0102(86)90062-3  0.345
1985 Geddes JW, Monaghan DT, Cotman CW, Lott IT, Kim RC, Chui HC. Plasticity of hippocampal circuitry in Alzheimer's disease. Science (New York, N.Y.). 230: 1179-81. PMID 4071042 DOI: 10.1126/Science.4071042  0.359
1985 Whittemore SR, Nieto-Sampedro M, Needels DL, Cotman CW. Neuronotrophic factors for mammalian brain neurons: injury induction in neonatal, adult and aged rat brain. Brain Research. 352: 169-78. PMID 4027662 DOI: 10.1016/0165-3806(85)90102-6  0.321
1985 Needels DL, Nieto-Sampedro M, Whittemore SR, Cotman CW. Neuronotrophic activity for ciliary ganglion neurons. Induction following injury to the brain of neonatal, adult, and aged rats. Brain Research. 350: 275-84. PMID 3986618 DOI: 10.1016/0165-3806(85)90271-8  0.301
1985 Altschuler RA, Monaghan DT, Haser WG, Wenthold RJ, Curthoys NP, Cotman CW. Immunocytochemical localization of glutaminase-like and aspartate aminotransferase-like immunoreactivities in the rat and guinea pig hippocampus. Brain Research. 330: 225-33. PMID 3886076 DOI: 10.1016/0006-8993(85)90681-X  0.547
1984 DeKosky ST, Scheff SW, Cotman CW. Elevated corticosterone levels. A possible cause of reduced axon sprouting in aged animals. Neuroendocrinology. 38: 33-8. PMID 6537997 DOI: 10.1159/000123862  0.304
1983 Vijayan VK, Cotman CW. Lysosomal enzyme changes in young and aged control and entorhinal-lesioned rats. Neurobiology of Aging. 4: 13-23. PMID 6877483 DOI: 10.1016/0197-4580(83)90049-0  0.304
1982 Nieto-Sampedro M, Lewis ER, Cotman CW, Manthorpe M, Skaper SD, Barbin G, Longo FM, Varon S. Brain injury causes a time-dependent increase in neuronotrophic activity at the lesion site. Science (New York, N.Y.). 217: 860-1. PMID 7100931 DOI: 10.1126/Science.7100931  0.301
1982 Scheff SW, Cotman CW. Chronic glucocorticoid therapy alters axon sprouting in the hippocampal dentate gyrus. Experimental Neurology. 76: 644-54. PMID 7084379 DOI: 10.1016/0014-4886(82)90131-5  0.314
1982 Hoff SF, Scheff SW, Cotman CW. Lesion-induced synaptogenesis in the dentate gyrus of aged rats: II. Demonstration of an impaired degeneration clearing response. The Journal of Comparative Neurology. 205: 253-9. PMID 7076896 DOI: 10.1002/Cne.902050305  0.305
1981 Sampedro M, Bussineau C, Cotman C. Postsynaptic density antigens: preparation and characterization of an antiserum against postsynaptic densities. Journal of Cell Biology. 90: 675-686. PMID 6169734 DOI: 10.1083/Jcb.90.3.675  0.323
1980 Goldowitz D, Cotman CW. Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study. Neuroscience. 5: 2163-74. PMID 6162129 DOI: 10.1016/0306-4522(80)90133-5  0.519
1980 Goldowitz D, Cotman CW. Do neurotrophic interactions control synapse formation in the adult rat brain? Brain Research. 181: 325-44. PMID 6153147 DOI: 10.1016/0006-8993(80)90616-2  0.54
1980 Cotman CW. Specificity of synaptic growth in brain: remodeling induced by kainic acid lesions. Progress in Brain Research. 51: 203-15. PMID 551480 DOI: 10.1016/S0079-6123(08)61306-0  0.301
1979 Haycock JW, Levy WB, Denner LA, Cotman CW. Stimulus-secretion coupling processes in brain: dependence upon extracellular calcium concentration. Neuroscience. 4: 1341-6. PMID 492540 DOI: 10.1016/0306-4522(79)90161-1  0.531
1979 Goldowitz D, Scheff SW, Cotman CW. The specificity of reactive synaptogenesis: a comparative study in the adult rat hippocampal formation. Brain Research. 170: 427-41. PMID 466422 DOI: 10.1016/0006-8993(79)90962-4  0.553
1979 Rostas JA, Kelly PT, Pesin RH, Cotman CW. Protein and glycoprotein composition of synaptic junctions prepared from discrete synaptic regions and different species. Brain Research. 168: 151-67. PMID 455075 DOI: 10.1016/0006-8993(79)90133-1  0.617
1979 Cotman CW, Scheff SW. Compensatory synapse growth in aged animals after neuronal death. Mechanisms of Ageing and Development. 9: 103-17. PMID 439948 DOI: 10.1016/0047-6374(79)90124-6  0.347
1978 Scheff SW, Bernardo LS, Cotman CW. Decrease in adrenergic axon sprouting in the senescent rat. Science (New York, N.Y.). 202: 775-8. PMID 715443 DOI: 10.1126/Science.715443  0.305
1978 Goldowitz D, Cotman CW. Induction of extensive fimbrial branching in the adult rat brain [18] Nature. 275: 64-67. PMID 683343 DOI: 10.1038/275064A0  0.543
1978 Haycock JW, Levy WB, Denner LA, Cotman CW. Effects of elevated [K+]O on the release of neurotransmitters from cortical synaptosomes: efflux or secretion? Journal of Neurochemistry. 30: 1113-25. PMID 660189  0.463
1978 Nadler JV, Perry BW, Cotman CW. Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature. 271: 676-7. PMID 625338 DOI: 10.1038/271676a0  0.328
1978 Haycock JW, Levy WB, Cotman CW. Stimulation-dependent depression of neurotransmitter release in brain: [Ca2+]o dependence. Brain Research. 155: 192-5. PMID 28816 DOI: 10.1016/0006-8993(78)90324-4  0.536
1977 Cotman C, Gentry C, Steward O. Synaptic replacement in the dentate gyrus after unilateral entorhinal lesion: electron microscopic analysis of the extent of replacement of synapses by the remaining entorhinal cortex. Journal of Neurocytology. 6: 455-64. PMID 894334 DOI: 10.1007/BF01178228  0.492
1977 Rostas JA, Kelly PT, Cotman CW. The identification of membrane glycocomponents in polyacrylamide gels: a rapid method using 125I-labeled lectins. Analytical Biochemistry. 80: 366-72. PMID 889076 DOI: 10.1016/0003-2697(77)90657-1  0.566
1977 Haycock JW, Levy WB, Cotman CW. Pentobarbital depression of stimulus-secretion coupling in brain--selective inhibition of depolarization-induced calcium-dependent release. Biochemical Pharmacology. 26: 159-61. PMID 319804 DOI: 10.1016/0006-2952(77)90389-6  0.537
1977 Steward O, White WF, Cotman CW. Potentiation of the excitatory synaptic action of commissural, associational and entorhinal afferents to dentate granule cells. Brain Research. 134: 551-60. PMID 198066 DOI: 10.1016/0006-8993(77)90830-7  0.481
1976 Churchill L, Cotman C, Banker G, Kelly P, Shannon L. Carbohydrate composition of central nervous system synapses. Analysis of isolated synaptic junctional complexes and postsynaptic densities. Biochimica Et Biophysica Acta. 448: 57-72. PMID 971428 DOI: 10.1016/0005-2736(76)90076-6  0.516
1976 White WF, Goldowitz D, Lynch G, Cotman CW. Electrophysiological analysis of the projection from the contralateral entorhinal cortex to the dentate gyrus in normal rats. Brain Research. 114: 201-9. PMID 963548 DOI: 10.1016/0006-8993(76)90666-1  0.529
1976 Steward O, Cotman C, Lynch G. A quantitative autoradiographic and electrophysiological study of the reinnervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions. Brain Research. 114: 181-200. PMID 963547 DOI: 10.1016/0006-8993(76)90665-X  0.485
1976 Levy WB, Haycock JW, Cotman CW. Stimulation-dependent depression of readily releasable neurotransmitter pools in brain. Brain Research. 115: 243-56. PMID 788858 DOI: 10.1016/0006-8993(76)90510-2  0.521
1976 Steward O, White CW, Cotman CW, Lynch G. Potentiation of excitatory synaptic transmission in the normal and in the reinnervated dentate gyrus of the rat. Experimental Brain Research. 26: 423-41. PMID 187442  0.426
1976 Cotman CW, Haycock JW, Levy WB. On the functional coupling of neurotransmitter uptake and release in brain. British Journal of Pharmacology. 58: 569-72. PMID 11862 DOI: 10.1111/J.1476-5381.1976.Tb08625.X  0.527
1976 Cotman CW, Haycock JW, Levy WB. K+ dependent release of gaba from isolated brain synaptosomes: secretion? Trans.Amer.Soc.Neurochem.. 7: No.312.  0.483
1975 Goldowitz D, White WF, Steward O, Lynch G, Cotman C. Anatomical evidence for a projection from the entorhinal cortex to the contralateral dentate gyrus of the rat. Experimental Neurology. 47: 433-41. PMID 1132457 DOI: 10.1016/0014-4886(75)90075-8  0.626
1974 Levy WB, Haycock JW, Cotman CW. Effects of polyvalent cations on stimulus-coupled secretion of (14C)-gamma-aminobutyric acid from isolated brain synaptosomes. Molecular Pharmacology. 10: 438-49. PMID 4851770  0.492
1974 Banker G, Churchill L, Cotman CW. Proteins of the postsynaptic density. The Journal of Cell Biology. 63: 456-65. PMID 4419608 DOI: 10.1083/Jcb.63.2.456  0.512
1974 Steward O, Cotman CW, Lynch GS. Growth of a new fiber projection in the brain of adult rats: Re-innervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions. Experimental Brain Research. 20: 45-66. PMID 4367724 DOI: 10.1007/BF00239017  0.492
1974 Cotman CW, Banker G, Churchill L, Taylor D. Isolation of postsynaptic densities from rat brain. The Journal of Cell Biology. 63: 441-55. PMID 4138148 DOI: 10.1083/Jcb.63.2.441  0.514
1973 Steward O, Cotman CW, Lynch GS. Re-establishment of electrophysiologically functional entorhinal cortical input to the dentate gyrus deafferented by ipsilateral entorhinal lesions: innervation by the contralateral entorhinal cortex. Experimental Brain Research. 18: 396-414. PMID 4778785 DOI: 10.1007/BF00239108  0.487
1973 Churchill L, Banker G, Cotman CW. Gradient design to optimize rate zonal separations. Analytical Biochemistry. 56: 370-82. PMID 4765633 DOI: 10.1016/0003-2697(73)90203-0  0.475
1973 Steward O, Cotman C, Lynch G. The nature of increased histochemical deposition of INT formazan in fields of degenerating synaptic terminals. Brain Research. 63: 183-93. PMID 4764296 DOI: 10.1016/0006-8993(73)90087-5  0.476
1973 Levy WB, Redburn DA, Cotman CW. Stimulus-coupled secretion of gamma-aminobutyric acid from rat brain synaptosomes. Science (New York, N.Y.). 181: 676-8. PMID 4724481 DOI: 10.1126/science.181.4100.676  0.546
1973 Cotman CW, Matthews DA, Taylor D, Lynch G. Synaptic rearrangement in the dentate gyrus: histochemical evidence of adjustments after lesions in immature and adult rats Proceedings of the National Academy of Sciences of the United States of America. 70. PMID 4519639 DOI: 10.1073/PNAS.70.12.3473  0.302
1973 Nadler JV, Cotman CW, Lynch GS. Altered distribution of choline acetyltransferase and acetylcholinesterase activities in the developing rat dentate gyrus following entorhinal lesion. Brain Research. 63: 215-20. PMID 4357969 DOI: 10.1016/0006-8993(73)90090-5  0.305
1973 Steward O, Lynch G, Cotman C. Histochemical detection of orthograde degeneration in the central nervous system of the rat. Brain Research. 54: 65-73. PMID 4122685 DOI: 10.1016/0006-8993(73)90034-6  0.51
1972 Banker G, Crain B, Cotman CW. Molecular weights of the polypeptide chains of synaptic plasma membranes. Brain Research. 42: 508-13. PMID 5050181 DOI: 10.1016/0006-8993(72)90551-3  0.492
1972 Banker GA, Cotman CW. Measurement of free electrophoretic mobility and retardation coefficient of protein-sodium dodecyl sulfate complexes by gel electrophoresis. A method to validate molecular weight estimates. The Journal of Biological Chemistry. 247: 5856-61. PMID 4560419  0.414
1971 Banker G, Cotman CW. Characteristics of different amino acids as protein precursors in mouse brain: advantages of certain carboxyl-labeled amino acids. Archives of Biochemistry and Biophysics. 142: 565-73. PMID 5550159 DOI: 10.1016/0003-9861(71)90520-0  0.507
1971 Cotman CW, Banker G, Zornetzer SF, McGaugh JL. Electroshock effects on brain protein synthesis: relation to brain seizures and retrograde amnesia. Science (New York, N.Y.). 173: 454-6. PMID 5104968 DOI: 10.1126/Science.173.3995.454  0.53
1971 Cotman CW, Banker G, Levy W, Taylor D. An ultrastructural and chemical analysis of the effect of triton X-100 on synaptic plasma membranes. Biochimica Et Biophysica Acta. 249: 406-18. PMID 4109143 DOI: 10.1016/0005-2736(71)90119-2  0.513
1968 Cotman CW, Mahler HR, Hugli TE. Isolation and characterization of insoluble proteins of the synaptic plasma membrane. Archives of Biochemistry and Biophysics. 126: 821-37. PMID 5686594 DOI: 10.1016/0003-9861(68)90476-1  0.501
1968 Cotman C, Mahler HR, Anderson NG. Isolation of a membrane fraction enriched in nerve-end membranes from rat brain by zonal cetrifugation. Biochimica Et Biophysica Acta. 163: 272-5. PMID 4301074  0.435
1967 Cotman CW, Mahler HR. Resolution of insoluble proteins in rat brain subcellular fractions. Archives of Biochemistry and Biophysics. 120: 384-96. PMID 6033455 DOI: 10.1016/0003-9861(67)90255-X  0.511
1966 Jayaraman J, Cotman C, Mahler HR, Sharp CW. Biochemical correlates of respiratory deficiency. VII. Glucose repression. Archives of Biochemistry and Biophysics. 116: 224-51. PMID 5961836 DOI: 10.1016/0003-9861(66)90029-4  0.494
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