| Year |
Citation |
Score |
| 2023 |
Churchman LR, Giang PD, Buczynski JB, Stok JE, Bell SG, De Voss JJ. Synthesis of substituted norcaranes for use as probes of enzyme mechanisms. Organic & Biomolecular Chemistry. PMID 38037692 DOI: 10.1039/d3ob01571h |
0.339 |
|
| 2023 |
Lee JHZ, Bruning JB, Bell SG. An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase. Chemistry (Weinheim An Der Bergstrasse, Germany). e202303335. PMID 37971151 DOI: 10.1002/chem.202303335 |
0.372 |
|
| 2023 |
Podgorski MN, Lee JHZ, Harbort JS, Nguyen GTH, Doherty DZ, Donald WA, Harmer JR, Bruning JB, Bell SG. Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant. Journal of Inorganic Biochemistry. 249: 112391. PMID 37837941 DOI: 10.1016/j.jinorgbio.2023.112391 |
0.305 |
|
| 2023 |
Ghith A, Bell SG. The oxidation of steroid derivatives by the CYP125A6 and CYP125A7 enzymes from Mycobacterium marinum. The Journal of Steroid Biochemistry and Molecular Biology. 235: 106406. PMID 37793577 DOI: 10.1016/j.jsbmb.2023.106406 |
0.394 |
|
| 2023 |
Doherty DZ, Ghith A, Ho A, De Voss JJ, Bell SG. The bacterial cytochrome P450 (CYP) CYP125 enzymes can competitively oxidise sitosterol in the presence of cholesterol. Chemical Communications (Cambridge, England). PMID 37435674 DOI: 10.1039/d3cc02312e |
0.306 |
|
| 2023 |
Podgorski MN, Keto AB, Coleman T, Bruning JB, De Voss JJ, Krenske EH, Bell SG. The Oxidation of Oxygen and Sulfur-Containing Heterocycles by Cytochrome P450 Enzymes. Chemistry (Weinheim An Der Bergstrasse, Germany). e202301371. PMID 37338048 DOI: 10.1002/chem.202301371 |
0.401 |
|
| 2023 |
Ghith A, Bruning JB, Bell SG. The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum. The Journal of Steroid Biochemistry and Molecular Biology. 231: 106317. PMID 37141947 DOI: 10.1016/j.jsbmb.2023.106317 |
0.382 |
|
| 2023 |
Coleman T, Podgorski MN, Doyle ML, Scaffidi-Muta JM, Campbell EC, Bruning JB, De Voss JJ, Bell SG. Cytochrome P450-catalyzed oxidation of halogen-containing substrates. Journal of Inorganic Biochemistry. 244: 112234. PMID 37116269 DOI: 10.1016/j.jinorgbio.2023.112234 |
0.439 |
|
| 2023 |
Akter J, Stockdale TP, Child SA, Lee JHZ, De Voss JJ, Bell SG. Selective carbon-hydrogen bond hydroxylation using an engineered cytochrome P450 peroxygenase. Journal of Inorganic Biochemistry. 244: 112209. PMID 37080140 DOI: 10.1016/j.jinorgbio.2023.112209 |
0.372 |
|
| 2023 |
Miller JC, Lee JHZ, Mclean MA, Chao RR, Stone ISJ, Pukala TL, Bruning JB, De Voss JJ, Schuler MA, Sligar SG, Bell SG. Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme. Journal of the American Chemical Society. PMID 37042073 DOI: 10.1021/jacs.3c01456 |
0.344 |
|
| 2023 |
Mohamed H, Ghith A, Bell SG. The binding of nitrogen-donor ligands to the ferric and ferrous forms of cytochrome P450 enzymes. Journal of Inorganic Biochemistry. 242: 112168. PMID 36870164 DOI: 10.1016/j.jinorgbio.2023.112168 |
0.308 |
|
| 2023 |
Ghith A, Bruning JB, Bell SG. The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum. Archives of Biochemistry and Biophysics. 109554. PMID 36842492 DOI: 10.1016/j.abb.2023.109554 |
0.387 |
|
| 2023 |
Giang PD, Churchman LR, Stok JE, Bell SG, De Voss JJ. Cymredoxin, a [2Fe-2S] ferredoxin, supports catalytic activity of the p-cymene oxidising P450 enzyme CYP108N12. Archives of Biochemistry and Biophysics. 737: 109549. PMID 36801262 DOI: 10.1016/j.abb.2023.109549 |
0.354 |
|
| 2022 |
Harlington AC, Shearwin KE, Bell SG, Whelan F. Efficient -demethylation of lignin monoaromatics using the peroxygenase activity of cytochrome P450 enzymes. Chemical Communications (Cambridge, England). PMID 36346098 DOI: 10.1039/d2cc04698a |
0.332 |
|
| 2022 |
Coleman T, Doherty DZ, Zhang T, Podgorski MN, Qiao R, Lee JHZ, Bruning JB, De Voss JJ, Zhou W, Bell SG. Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation. Chemistry, An Asian Journal. PMID 36268769 DOI: 10.1002/asia.202200986 |
0.375 |
|
| 2022 |
Podgorski MN, Coleman T, Churchman LR, Bruning JB, De Voss JJ, Bell SG. Investigating the active oxidants involved in cytochrome P450 catalyzed sulfoxidation reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36169207 DOI: 10.1002/chem.202202428 |
0.333 |
|
| 2022 |
Coleman T, Lee J, Kirk AM, Doherty DZ, Podgorski MN, Pinidiya DK, Bruning JB, De Voss JJ, Krenske EH, Bell SG. Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36043399 DOI: 10.1002/chem.202201895 |
0.377 |
|
| 2022 |
Ghith A, Doherty DZ, Bruning JB, Russell RA, De Voss JJ, Bell SG. The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from and . Acs Infectious Diseases. PMID 35881654 DOI: 10.1021/acsinfecdis.2c00215 |
0.407 |
|
| 2022 |
Lee J, Podgorski M, Moir M, Gee AR, Bell SG. Selective oxidations using a cytochrome P450 enzyme variant driven with surrogate oxygen donors and light. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 35712785 DOI: 10.1002/chem.202201366 |
0.321 |
|
| 2022 |
Mohamed H, Child SA, Bruning JB, Bell SG. A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis. The Journal of Steroid Biochemistry and Molecular Biology. 221: 106097. PMID 35346833 DOI: 10.1016/j.jsbmb.2022.106097 |
0.343 |
|
| 2021 |
Podgorski MN, Coleman T, Giang PD, Wang CR, Bruning JB, Bernhardt PV, De Voss JJ, Bell SG. To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme. Inorganic Chemistry. PMID 34910500 DOI: 10.1021/acs.inorgchem.1c02786 |
0.386 |
|
| 2021 |
Chao RR, Lau IC, Coleman T, Churchman LR, Child SA, Lee JHZ, Bruning JB, De Voss JJ, Bell SG. The stereoselective oxidation of para-substituted benzenes by a cytochrome P450 biocatalyst. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34350662 DOI: 10.1002/chem.202102757 |
0.455 |
|
| 2020 |
Child SA, Ghith A, Bruning JB, Bell SG. A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis. Journal of Inorganic Biochemistry. 209: 111116. PMID 32473484 DOI: 10.1016/J.Jinorgbio.2020.111116 |
0.43 |
|
| 2020 |
Pederick JL, Thompson AP, Bell SG, Bruning JB. D-alanine-D-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations. The Journal of Biological Chemistry. PMID 32335509 DOI: 10.1074/Jbc.Ra120.012936 |
0.431 |
|
| 2020 |
Coleman T, Stok JE, Podgorski MN, Bruning JB, De Voss JJ, Bell SG. Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 32248305 DOI: 10.1007/S00775-020-01781-4 |
0.458 |
|
| 2020 |
Podgorski MN, Harbort JS, Coleman T, Stok JE, Yorke JA, Wong LL, Bruning JB, Bernhardt PV, De Voss JJ, Harmer JR, Bell SG. Biophysical techniques to distinguish ligand binding modes in cytochrome P450 monooxygenases. Biochemistry. PMID 32058707 DOI: 10.1021/Acs.Biochem.0C00027 |
0.678 |
|
| 2020 |
Sarkar MR, Bell SG. Complementary and selective oxidation of hydrocarbon derivatives by two cytochrome P450 enzymes of the same family Catalysis Science & Technology. 10: 5983-5995. DOI: 10.1039/D0Cy01040E |
0.514 |
|
| 2019 |
Podgorski MN, Coleman T, Chao RR, De Voss JJ, Bruning JB, Bell SG. Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. Journal of Inorganic Biochemistry. 203: 110913. PMID 31759265 DOI: 10.1016/J.Jinorgbio.2019.110913 |
0.481 |
|
| 2019 |
Sarkar MR, Houston SD, Savage GP, Williams CM, Krenske EH, Bell SG, De Voss JJ. Rearrangement-Free Hydroxylation of Methylcubanes by a Cytochrome P450: The Case for Dynamical Coupling of C-H Abstraction and Rebound. Journal of the American Chemical Society. PMID 31739667 DOI: 10.1021/Jacs.9B08064 |
0.399 |
|
| 2019 |
Liang W, Carraro F, Solomon MB, Bell SG, Amenitsch H, Sumby CJ, White NG, Falcaro P, Doonan CJ. Enzyme Encapsulation in a Porous Hydrogen-Bonded Organic Framework. Journal of the American Chemical Society. PMID 31426638 DOI: 10.1021/Jacs.9B06589 |
0.335 |
|
| 2019 |
Lau ICK, Feyereisen R, Nelson DR, Bell SG. Analysis and preliminary characterisation of the cytochrome P450 monooxygenases from Frankia sp. EuI1c (Frankia inefficax sp.). Archives of Biochemistry and Biophysics. PMID 31082352 DOI: 10.1016/J.Abb.2019.05.007 |
0.402 |
|
| 2019 |
Child SA, Flint KL, Bruning JB, Bell SG. The characterisation of two members of the cytochrome P450 CYP150 family: CYP150A5 and CYP150A6 from Mycobacterium marinum. Biochimica Et Biophysica Acta. General Subjects. PMID 30826435 DOI: 10.1016/J.Bbagen.2019.02.016 |
0.332 |
|
| 2019 |
Liang W, Xu H, Carraro F, Maddigan NK, Li Q, Bell SG, Huang DM, Tarzia A, Solomon MB, Amenitsch H, Vaccari L, Sumby CJ, Falcaro P, Doonan CJ. Enhanced Activity of Enzymes Encapsulated in Hydrophilic Metal-Organic Frameworks. Journal of the American Chemical Society. PMID 30636404 DOI: 10.1021/Jacs.8B10302 |
0.327 |
|
| 2019 |
Dezvarei S, Shoji O, Watanabe Y, Bell SG. The effect of decoy molecules on the activity of the P450Bm3 holoenzyme and a heme domain peroxygenase variant Catalysis Communications. 124: 97-102. DOI: 10.1016/J.Catcom.2019.03.004 |
0.365 |
|
| 2018 |
Lee JHZ, Wong SH, Stok JE, Bagster SA, Beckett J, Clegg JK, Brock A, De Voss JJ, Bell SG. Selective hydroxylation of 1,8- and 1,4-cineole using bacterial P450 variants. Archives of Biochemistry and Biophysics. PMID 30590022 DOI: 10.1016/J.Abb.2018.12.025 |
0.398 |
|
| 2018 |
Day A, Lee J, Phan QD, Lam HC, Ametovski A, Sumby C, Bell S, George JH. Biomimetic and Biocatalytic Synthesis of Bruceol. Angewandte Chemie (International Ed. in English). PMID 30548759 DOI: 10.1002/Anie.201812432 |
0.315 |
|
| 2018 |
Child SA, Bradley JM, Pukala TL, Svistunenko DA, Le Brun NE, Bell SG. Electron transfer ferredoxins with unusual cluster binding motifs support secondary metabolism in many bacteria. Chemical Science. 9: 7948-7957. PMID 30542550 DOI: 10.1039/C8Sc01286E |
0.401 |
|
| 2018 |
Child SA, Rossi VP, Bell SG. Selective ϖ-1 oxidation of fatty acids by CYP147G1 from Mycobacterium marinum. Biochimica Et Biophysica Acta. General Subjects. PMID 30476524 DOI: 10.1016/J.Bbagen.2018.11.013 |
0.349 |
|
| 2018 |
Dezvarei S, Onoda H, Shoji O, Watanabe Y, Bell SG. Efficient hydroxylation of cycloalkanes by co-addition of decoy molecules to variants of the cytochrome P450 CYP102A1. Journal of Inorganic Biochemistry. PMID 29526504 DOI: 10.1016/J.Jinorgbio.2018.03.001 |
0.481 |
|
| 2018 |
Dezvarei S, Lee JHZ, Bell SG. Stereoselective hydroxylation of isophorone by variants of the cytochromes P450 CYP102A1 and CYP101A1. Enzyme and Microbial Technology. 111: 29-37. PMID 29421034 DOI: 10.1016/J.Enzmictec.2018.01.002 |
0.474 |
|
| 2018 |
Child SA, Naumann EF, Bruning JB, Bell SG. Structural and functional characterisation of the cytochrome P450 enzyme CYP268A2 from Mycobacterium marinum. The Biochemical Journal. PMID 29343612 DOI: 10.2210/Pdb6Bld/Pdb |
0.501 |
|
| 2018 |
Coleman T, Wong SH, Podgorski MN, Bruning JB, Voss JJD, Bell SG. Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation Acs Catalysis. 8: 5915-5927. DOI: 10.1021/Acscatal.8B00909 |
0.477 |
|
| 2017 |
Bowen AM, Johnson EOD, Mercuri F, Hoskins NJ, Qiao R, McCullagh JSO, Lovett JE, Bell SG, Zhou W, Timmel CR, Wong LL, Harmer JR. A Structural Model of a P450-Ferredoxin Complex from Orientation-Selective Double Electron-Electron Resonance Spectroscopy. Journal of the American Chemical Society. PMID 29266939 DOI: 10.1021/Jacs.7B11056 |
0.682 |
|
| 2017 |
Sarkar MR, Lee JHZ, Bell SG. The oxidation of hydrophobic aromatic substrates using a variant of the P450 monooxygenase CYP101B1. Chembiochem : a European Journal of Chemical Biology. PMID 28868671 DOI: 10.1002/Cbic.201700316 |
0.524 |
|
| 2017 |
Wong SH, Bell SG, De Voss JJ. P450 catalysed dehydrogenation Pure and Applied Chemistry. 89: 841-852. DOI: 10.1515/Pac-2016-1216 |
0.404 |
|
| 2017 |
Hall EA, Sarkar MR, Bell SG. The selective oxidation of substituted aromatic hydrocarbons and the observation of uncoupling via redox cycling during naphthalene oxidation by the CYP101B1 system Catalysis Science & Technology. 7: 1537-1548. DOI: 10.1039/C7Cy00088J |
0.362 |
|
| 2017 |
Munday SD, Dezvarei S, Lau IC, Bell SG. Examination of Selectivity in the Oxidation of ortho
- and meta
-Disubstituted Benzenes by CYP102A1 (P450 Bm3) Variants Chemcatchem. 9: 2512-2522. DOI: 10.1002/Cctc.201700116 |
0.425 |
|
| 2016 |
Maddigan NK, Bell SG. The self-sufficient CYP102 family enzyme, Krac9955, from Ktedonobacter racemifer DSM44963 acts as an alkyl- and alkyloxy-benzoic acid hydroxylase. Archives of Biochemistry and Biophysics. PMID 28048974 DOI: 10.1016/J.Abb.2016.12.014 |
0.449 |
|
| 2016 |
Coleman T, Chao RR, De Voss JJ, Bell SG. The importance of the benzoic acid carboxylate moiety for substrate recognition by CYP199A4 from Rhodopseudomonas palustris HaA2. Biochimica Et Biophysica Acta. 1864: 667-75. PMID 26969786 DOI: 10.1016/J.Bbapap.2016.03.006 |
0.45 |
|
| 2016 |
Munday SD, Maddigan NK, Young RJ, Bell SG. Characterisation of two self-sufficient CYP102 family monooxygenases from Ktedonobacter racemifer DSM44963 which have new fatty acid alcohol product profiles. Biochimica Et Biophysica Acta. PMID 26825771 DOI: 10.1016/J.Bbagen.2016.01.023 |
0.407 |
|
| 2016 |
Chao RR, De Voss JJ, Bell SG. The efficient and selective catalytic oxidation of para-substituted cinnamic acid derivatives by the cytochrome P450 monooxygenase, CYP199A4 Rsc Advances. 6: 55286-55297. DOI: 10.1039/C6Ra11025H |
0.482 |
|
| 2016 |
Hall EA, Sarkar MR, Lee JHZ, Munday SD, Bell SG. Improving the Monooxygenase Activity and the Regio- and Stereoselectivity of Terpenoid Hydroxylation Using Ester Directing Groups Acs Catalysis. 6: 6306-6317. DOI: 10.1021/Acscatal.6B01882 |
0.405 |
|
| 2016 |
Stok JE, Hall EA, Stone ISJ, Noble MC, Wong SH, Bell SG, De Voss JJ. In vivo and in vitro hydroxylation of cineole and camphor by cytochromes P450CYP101A1, CYP101B1 and N242A CYP176A1 Journal of Molecular Catalysis B: Enzymatic. 128: 52-64. DOI: 10.1016/J.Molcatb.2016.03.004 |
0.387 |
|
| 2016 |
Chao RR, Lau IC-, Voss JJD, Bell SG. Modification of an Enzyme Biocatalyst for the Efficient and Selective Oxidative Demethylation of para‐Substituted Benzene Derivatives Chemcatchem. 8: 3626-3635. DOI: 10.1002/Cctc.201600951 |
0.485 |
|
| 2016 |
Munday SD, Dezvarei S, Bell SG. Increasing the Activity and Efficiency of Stereoselective Oxidations by using Decoy Molecules in Combination with Rate-Enhancing Variants of P450Bm3 Chemcatchem. 8: 2789-2796. DOI: 10.1002/Cctc.201600551 |
0.44 |
|
| 2015 |
Munday SD, Shoji O, Watanabe Y, Wong LL, Bell SG. Improved oxidation of aromatic and aliphatic hydrocarbons using rate enhancing variants of P450Bm3 in combination with decoy molecules. Chemical Communications (Cambridge, England). PMID 26593228 DOI: 10.1039/C5Cc09247G |
0.622 |
|
| 2015 |
Liang K, Coghlan CJ, Bell SG, Doonan C, Falcaro P. Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation. Chemical Communications (Cambridge, England). PMID 26548587 DOI: 10.1039/C5Cc07577G |
0.31 |
|
| 2015 |
Zhang A, Zhang T, Hall EA, Hutchinson S, Cryle MJ, Wong LL, Zhou W, Bell SG. The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis. Molecular Biosystems. 11: 869-81. PMID 25587700 DOI: 10.1039/C4Mb00665H |
0.721 |
|
| 2015 |
Coleman T, Chao RR, Bruning JB, De Voss JJ, Bell SG. CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives Rsc Advances. 5: 52007-52018. DOI: 10.1039/C5Ra08730A |
0.469 |
|
| 2015 |
Hall EA, Bell SG. The efficient and selective biocatalytic oxidation of norisoprenoid and aromatic substrates by CYP101B1 from Novosphingobium aromaticivorans DSM12444 Rsc Advances. 5: 5762-5773. DOI: 10.1039/C4Ra14010A |
0.441 |
|
| 2014 |
Zhang T, Zhang A, Bell SG, Wong LL, Zhou W. The structure of a novel electron-transfer ferredoxin from Rhodopseudomonas palustris HaA2 which contains a histidine residue in its iron-sulfur cluster-binding motif. Acta Crystallographica. Section D, Biological Crystallography. 70: 1453-64. PMID 24816113 DOI: 10.1107/S139900471400474X |
0.637 |
|
| 2014 |
Bell SG, Spence JT, Liu S, George JH, Wong LL. Selective aliphatic carbon-hydrogen bond activation of protected alcohol substrates by cytochrome P450 enzymes. Organic & Biomolecular Chemistry. 12: 2479-88. PMID 24599100 DOI: 10.1039/C3Ob42417K |
0.666 |
|
| 2013 |
Vohra S, Musgaard M, Bell SG, Wong LL, Zhou W, Biggin PC. The dynamics of camphor in the cytochrome P450 CYP101D2. Protein Science : a Publication of the Protein Society. 22: 1218-29. PMID 23832606 DOI: 10.1002/Pro.2309 |
0.643 |
|
| 2013 |
Bell SG, French L, Rees NH, Cheng SS, Preston G, Wong LL. A phthalate family oxygenase reductase supports terpene alcohol oxidation by CYP238A1 from Pseudomonas putida KT2440. Biotechnology and Applied Biochemistry. 60: 9-17. PMID 23586988 DOI: 10.1002/Bab.1084 |
0.677 |
|
| 2013 |
Bell SG, Yang W, Dale A, Zhou W, Wong LL. Improving the affinity and activity of CYP101D2 for hydrophobic substrates. Applied Microbiology and Biotechnology. 97: 3979-90. PMID 22820521 DOI: 10.1007/S00253-012-4278-7 |
0.71 |
|
| 2012 |
Bell SG, Zhou R, Yang W, Tan AB, Gentleman AS, Wong LL, Zhou W. Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 16677-88. PMID 23135838 DOI: 10.1002/Chem.201202776 |
0.706 |
|
| 2012 |
Bell SG, McMillan JH, Yorke JA, Kavanagh E, Johnson EO, Wong LL. Tailoring an alien ferredoxin to support native-like P450 monooxygenase activity. Chemical Communications (Cambridge, England). 48: 11692-4. PMID 23104016 DOI: 10.1039/C2Cc35968E |
0.809 |
|
| 2012 |
Bell SG, Yang W, Tan AB, Zhou R, Johnson EO, Zhang A, Zhou W, Rao Z, Wong LL. The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site. Dalton Transactions (Cambridge, England : 2003). 41: 8703-14. PMID 22695988 DOI: 10.1039/C2Dt30783A |
0.814 |
|
| 2012 |
Abdalla JA, Bowen AM, Bell SG, Wong LL, Timmel CR, Harmer J. Characterisation of the paramagnetic [2Fe-2S]+ centre in palustrisredoxin-B (PuxB) from Rhodopseudomonas palustris CGA009: g-matrix determination and spin coupling analysis. Physical Chemistry Chemical Physics : Pccp. 14: 6526-37. PMID 22460919 DOI: 10.1039/C2Cp24112A |
0.586 |
|
| 2012 |
Bell SG, Yang W, Yorke JA, Zhou W, Wang H, Harmer J, Copley R, Zhang A, Zhou R, Bartlam M, Rao Z, Wong LL. Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme. Acta Crystallographica. Section D, Biological Crystallography. 68: 277-91. PMID 22349230 DOI: 10.1107/S090744491200145X |
0.724 |
|
| 2012 |
Whitehouse CJ, Bell SG, Wong LL. P450(BM3) (CYP102A1): connecting the dots. Chemical Society Reviews. 41: 1218-60. PMID 22008827 DOI: 10.1039/C1Cs15192D |
0.688 |
|
| 2011 |
Rowlatt B, Yorke JA, Strong AJ, Whitehouse CJ, Bell SG, Wong LL. Chain length-dependent cooperativity in fatty acid binding and oxidation by cytochrome P450BM3 (CYP102A1). Protein & Cell. 2: 656-71. PMID 21904981 DOI: 10.1007/S13238-011-1082-6 |
0.668 |
|
| 2011 |
Zhou R, Huang C, Zhang A, Bell SG, Zhou W, Wong LL. Crystallization and preliminary X-ray analysis of CYP153C1 from Novosphingobium aromaticivorans DSM12444. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 964-7. PMID 21821906 DOI: 10.1107/S174430911102464X |
0.622 |
|
| 2011 |
Whitehouse CJ, Yang W, Yorke JA, Tufton HG, Ogilvie LC, Bell SG, Zhou W, Bartlam M, Rao Z, Wong LL. Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant. Dalton Transactions (Cambridge, England : 2003). 40: 10383-96. PMID 21603690 DOI: 10.1039/C1Dt10098J |
0.711 |
|
| 2011 |
Whitehouse CJ, Rees NH, Bell SG, Wong LL. Dearomatisation of o-xylene by P450BM3 (CYP102A1). Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 6862-8. PMID 21523836 DOI: 10.1002/Chem.201002465 |
0.666 |
|
| 2011 |
Ma M, Bell SG, Yang W, Hao Y, Rees NH, Bartlam M, Zhou W, Wong LL, Rao Z. Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444. Chembiochem : a European Journal of Chemical Biology. 12: 88-99. PMID 21154803 DOI: 10.1002/Cbic.201000537 |
0.662 |
|
| 2011 |
Yang W, Bell SG, Wang H, Zhou W, Bartlam M, Wong LL, Rao Z. The structure of CYP101D2 unveils a potential path for substrate entry into the active site. The Biochemical Journal. 433: 85-93. PMID 20950270 DOI: 10.1042/Bj20101017 |
0.685 |
|
| 2010 |
Whitehouse CJ, Yang W, Yorke JA, Rowlatt BC, Strong AJ, Blanford CF, Bell SG, Bartlam M, Wong LL, Rao Z. Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3). Chembiochem : a European Journal of Chemical Biology. 11: 2549-56. PMID 21110374 DOI: 10.1002/Cbic.201000421 |
0.714 |
|
| 2010 |
Cryle MJ, Bell SG, Schlichting I. Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry. 49: 7282-96. PMID 20690619 DOI: 10.1021/Bi100910Y |
0.463 |
|
| 2010 |
Yang W, Bell SG, Wang H, Zhou W, Hoskins N, Dale A, Bartlam M, Wong LL, Rao Z. Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444. The Journal of Biological Chemistry. 285: 27372-84. PMID 20576606 DOI: 10.1074/Jbc.M110.118349 |
0.688 |
|
| 2010 |
Bell SG, Tan AB, Johnson EO, Wong LL. Selective oxidative demethylation of veratric acid to vanillic acid by CYP199A4 from Rhodopseudomonas palustris HaA2. Molecular Biosystems. 6: 206-14. PMID 20024082 DOI: 10.1039/B913487E |
0.8 |
|
| 2010 |
Bell SG, Xu F, Johnson EO, Forward IM, Bartlam M, Rao Z, Wong LL. Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 315-28. PMID 19904564 DOI: 10.1007/S00775-009-0604-7 |
0.806 |
|
| 2010 |
Bell SG, Dale A, Rees NH, Wong LL. A cytochrome P450 class I electron transfer system from Novosphingobium aromaticivorans. Applied Microbiology and Biotechnology. 86: 163-75. PMID 19779713 DOI: 10.1007/S00253-009-2234-Y |
0.696 |
|
| 2009 |
Lovett JE, Bowen AM, Timmel CR, Jones MW, Dilworth JR, Caprotti D, Bell SG, Wong LL, Harmer J. Structural information from orientationally selective DEER spectroscopy. Physical Chemistry Chemical Physics : Pccp. 11: 6840-8. PMID 19639159 DOI: 10.1039/B907010A |
0.573 |
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| 2009 |
Xu F, Bell SG, Peng Y, Johnson EO, Bartlam M, Rao Z, Wong LL. Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris. Proteins. 77: 867-80. PMID 19626710 DOI: 10.1002/Prot.22510 |
0.798 |
|
| 2009 |
Whitehouse CJ, Bell SG, Yang W, Yorke JA, Blanford CF, Strong AJ, Morse EJ, Bartlam M, Rao Z, Wong LL. A highly active single-mutation variant of P450BM3 (CYP102A1). Chembiochem : a European Journal of Chemical Biology. 10: 1654-6. PMID 19492389 DOI: 10.1002/Cbic.200900279 |
0.629 |
|
| 2009 |
Hong C, Bell SG, Yang W, Wang H, Hao Y, Li X, Zhou W, Bartlam M, Wong LL. Purification, crystallization and preliminary X-ray analysis of cytochrome P450 219A1 from Novosphingobium aromaticivorans DSM 12444. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 364-7. PMID 19342781 DOI: 10.1107/S1744309109005648 |
0.646 |
|
| 2009 |
Holland JP, Giansiracusa JH, Bell SG, Wong LL, Dilworth JR. In vitro kinetic studies on the mechanism of oxygen-dependent cellular uptake of copper radiopharmaceuticals. Physics in Medicine and Biology. 54: 2103-19. PMID 19287086 DOI: 10.1088/0031-9155/54/7/017 |
0.583 |
|
| 2009 |
Bell SG, Vallee BL. The Metallothionein/thionein system: An oxidoreductive metabolic zinc link Chembiochem. 10: 55-62. PMID 19089881 DOI: 10.1002/Cbic.200800511 |
0.321 |
|
| 2009 |
Xu F, Bell SG, Peng Y, Johnson EO, Bartlam M, Rao Z, Wong L. Correction to the article “Crystal Structure of a Ferredoxin Reductase for the CYP199A2 System from Rhodopseudomonas palustris
” Proteins: Structure, Function, and Bioinformatics. 78: 501-501. DOI: 10.1002/Prot.22627 |
0.754 |
|
| 2008 |
Whitehouse CJ, Bell SG, Wong LL. Desaturation of alkylbenzenes by cytochrome P450(BM3) (CYP102A1). Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10905-8. PMID 19003834 DOI: 10.1002/Chem.200801927 |
0.625 |
|
| 2008 |
Bell SG, Xu F, Forward I, Bartlam M, Rao Z, Wong LL. Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris. Journal of Molecular Biology. 383: 561-74. PMID 18762195 DOI: 10.1016/J.Jmb.2008.08.033 |
0.722 |
|
| 2008 |
Guo D, Xu F, Bell SG, Pang X, Bartlam M, Wong LL. Purification, crystallization and preliminary crystallographic analysis of CYP 195A2, a P450 enzyme from Rhodopseudomonas palustris. Protein and Peptide Letters. 15: 423-6. PMID 18473959 DOI: 10.2174/092986608784246470 |
0.662 |
|
| 2008 |
Whitehouse CJ, Bell SG, Tufton HG, Kenny RJ, Ogilvie LC, Wong LL. Evolved CYP102A1 (P450BM3) variants oxidise a range of non-natural substrates and offer new selectivity options. Chemical Communications (Cambridge, England). 966-8. PMID 18283351 DOI: 10.1039/B718124H |
0.615 |
|
| 2007 |
Xu F, Bell SG, Rao Z, Wong LL. Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam. Protein Engineering, Design & Selection : Peds. 20: 473-80. PMID 17962225 DOI: 10.1093/Protein/Gzm028 |
0.692 |
|
| 2007 |
Bell SG, Wong LL. P450 enzymes from the bacterium Novosphingobium aromaticivorans. Biochemical and Biophysical Research Communications. 360: 666-72. PMID 17618912 DOI: 10.1016/J.Bbrc.2007.06.119 |
0.71 |
|
| 2007 |
Peng Y, Xu F, Bell SG, Wong LL, Rao Z. Crystallization and preliminary X-ray diffraction studies of a ferredoxin reductase from Rhodopseudomonas palustris CGA009. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 422-5. PMID 17565187 DOI: 10.1107/S1744309107017411 |
0.631 |
|
| 2007 |
Pang X, Xu F, Bell SG, Guo D, Wong LL, Rao Z. Purification, crystallization and preliminary crystallographic analysis of cytochrome P450 203A1 from Rhodopseudomonas palustris. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 342-5. PMID 17401212 DOI: 10.1107/S1744309107012705 |
0.644 |
|
| 2007 |
Fleming BD, Bell SG, Wong LL, Bond AM. The electrochemistry of a heme-containing enzyme, CYP199A2, adsorbed directly onto a pyrolytic graphite electrode Journal of Electroanalytical Chemistry. 611: 149-154. DOI: 10.1016/J.Jelechem.2007.08.016 |
0.662 |
|
| 2006 |
Bell SG, Hoskins N, Xu F, Caprotti D, Rao Z, Wong LL. Cytochrome P450 enzymes from the metabolically diverse bacterium Rhodopseudomonas palustris. Biochemical and Biophysical Research Communications. 342: 191-6. PMID 16472768 DOI: 10.1016/J.Bbrc.2006.01.133 |
0.705 |
|
| 2005 |
Fleming BD, Zhang J, Bond AM, Bell SG, Wong LL. Separation of electron-transfer and coupled chemical reaction components of biocatalytic processes using Fourier transform ac voltammetry. Analytical Chemistry. 77: 3502-10. PMID 15924381 DOI: 10.1021/Ac048151Y |
0.613 |
|
| 2005 |
Xu F, Bell SG, Lednik J, Insley A, Rao Z, Wong LL. The heme monooxygenase cytochrome P450cam can be engineered to oxidize ethane to ethanol. Angewandte Chemie (International Ed. in English). 44: 4029-32. PMID 15912546 DOI: 10.1002/Anie.200462630 |
0.584 |
|
| 2005 |
Sowden RJ, Yasmin S, Rees NH, Bell SG, Wong LL. Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3. Organic & Biomolecular Chemistry. 3: 57-64. PMID 15602599 DOI: 10.1039/B413068E |
0.628 |
|
| 2004 |
Bell SG, Chen X, Xu F, Rao Z, Wong LL. Engineering substrate recognition in catalysis by cytochrome P450cam. Biochemical Society Transactions. 31: 558-62. PMID 12773156 DOI: 10.1042/Bst0310558 |
0.677 |
|
| 2003 |
Fleming BD, Tian Y, Bell SG, Wong LL, Urlacher V, Hill HA. Redox properties of cytochrome p450BM3 measured by direct methods. European Journal of Biochemistry / Febs. 270: 4082-8. PMID 14519119 DOI: 10.1046/J.1432-1033.2003.03799.X |
0.64 |
|
| 2003 |
Bell SG, Chen X, Sowden RJ, Xu F, Williams JN, Wong LL, Rao Z. Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam. Journal of the American Chemical Society. 125: 705-14. PMID 12526670 DOI: 10.1021/Ja028460A |
0.673 |
|
| 2003 |
Bell SG, Orton E, Boyd H, Stevenson JA, Riddle A, Campbell S, Wong LL. Engineering cytochrome P450cam into an alkane hydroxylase Dalton Transactions. 2133-2140. DOI: 10.1039/B300869J |
0.685 |
|
| 2003 |
Bentley EA, Astier Y, Ji WM, Bell SG, Wong L, Hill HO. The electrochemistry and scanning tunnelling microscopy of the flavoprotein putidaredoxin reductase on alkanethiol-modified gold Inorganica Chimica Acta. 356: 343-348. DOI: 10.1016/S0020-1693(03)00251-2 |
0.657 |
|
| 2002 |
Bell SG, Stevenson JA, Boyd HD, Campbell S, Riddle AD, Orton EL, Wong LL. Butane and propane oxidation by engineered cytochrome P450cam. Chemical Communications (Cambridge, England). 490-1. PMID 12120555 DOI: 10.1039/B110957J |
0.687 |
|
| 2002 |
Chen X, Christopher A, Jones JP, Bell SG, Guo Q, Xu F, Rao Z, Wong LL. Crystal structure of the F87W/Y96F/V247L mutant of cytochrome P-450cam with 1,3,5-trichlorobenzene bound and further protein engineering for the oxidation of pentachlorobenzene and hexachlorobenzene. The Journal of Biological Chemistry. 277: 37519-26. PMID 12114516 DOI: 10.1074/Jbc.M203762200 |
0.693 |
|
| 2002 |
Bell SG, Harford-Cross CF, Wong LL. Engineering the CYP101 system for in vivo oxidation of unnatural substrates. Protein Engineering. 14: 797-802. PMID 11739899 DOI: 10.1093/Protein/14.10.797 |
0.676 |
|
| 2001 |
Bell SG, Sowden RJ, Wong L. Engineering the haem monooxygenase cytochrome P450cam for monoterpene oxidation Chemical Communications. 635-636. DOI: 10.1039/B100290M |
0.678 |
|
| 1997 |
Bell SG, Rouch DA, Wong L. Selective aliphatic and aromatic carbon-hydrogen bond activation catalysed by mutants of cytochrome p450cam Journal of Molecular Catalysis B: Enzymatic. 3: 293-302. DOI: 10.1016/S1381-1177(97)00009-X |
0.641 |
|
| 1996 |
England PA, Rouch DA, Westlake ACG, Bell SG, Nickerson DP, Webberley M, Flitsch SL, Wong LL. Aliphatic vs. aromatic C-H bond activation of phenylcyclohexane catalysed by cytochrome P450cam Chemical Communications. 357-358. DOI: 10.1039/Cc9960000357 |
0.605 |
|
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