Arjun Krishnan - Publications

Affiliations: 
2011-2016 Lewis-Sigler Institute for Integrative Genomics Princeton University, Princeton, NJ 
 2017-2022 Computational Math, Sci Egr Michigan State University, East Lansing, MI 
 2022- Biomedical Informatics University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Biomedical informatics, Machine learning, Data integration
Website:
https://www.thekrishnanlab.org

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yuan H, Mancuso CA, Johnson K, Braasch I, Krishnan A. Computational strategies for cross-species knowledge transfer and translational biomedicine. Arxiv. PMID 39184546  0.681
2024 Gomez-Cano F, Rodriguez J, Zhou P, Chu YH, Magnusson E, Gomez-Cano L, Krishnan A, Springer NM, de Leon N, Grotewold E. Prioritizing Metabolic Gene Regulators through Multi-Omic Network Integration in Maize. Biorxiv : the Preprint Server For Biology. PMID 38464086 DOI: 10.1101/2024.02.26.582075  0.422
2024 Mancuso CA, Johnson KA, Liu R, Krishnan A. Joint representation of molecular networks from multiple species improves gene classification. Plos Computational Biology. 20: e1011773. PMID 38198480 DOI: 10.1371/journal.pcbi.1011773  0.341
2023 Palande S, Kaste JAM, Roberts MD, Segura Abá K, Claucherty C, Dacon J, Doko R, Jayakody TB, Jeffery HR, Kelly N, Manousidaki A, Parks HM, Roggenkamp EM, Schumacher AM, Yang J, ... ... Krishnan A, et al. Topological data analysis reveals a core gene expression backbone that defines form and function across flowering plants. Plos Biology. 21: e3002397. PMID 38051702 DOI: 10.1371/journal.pbio.3002397  0.431
2023 Mancuso CA, Liu R, Krishnan A. PyGenePlexus: A Python package for gene discovery using network-based machine learning. Bioinformatics (Oxford, England). PMID 36721325 DOI: 10.1093/bioinformatics/btad064  0.383
2023 Liu R, Hirn M, Krishnan A. Accurately modeling biased random walks on weighted networks using node2vec. Bioinformatics (Oxford, England). PMID 36688699 DOI: 10.1093/bioinformatics/btad047  0.303
2022 Hawkins NT, Maldaver M, Yannakopoulos A, Guare LA, Krishnan A. Systematic tissue annotations of genomics samples by modeling unstructured metadata. Nature Communications. 13: 6736. PMID 36347858 DOI: 10.1038/s41467-022-34435-x  0.351
2022 Hickey SL, McKim A, Mancuso CA, Krishnan A. A network-based approach for isolating the chronic inflammation gene signatures underlying complex diseases towards finding new treatment opportunities. Frontiers in Pharmacology. 13: 995459. PMID 36313344 DOI: 10.3389/fphar.2022.995459  0.415
2022 Mancuso CA, Bills PS, Krum D, Newsted J, Liu R, Krishnan A. GenePlexus: a web-server for gene discovery using network-based machine learning. Nucleic Acids Research. PMID 35580053 DOI: 10.1093/nar/gkac335  0.426
2022 Johnson KA, Krishnan A. Robust normalization and transformation techniques for constructing gene coexpression networks from RNA-seq data. Genome Biology. 23: 1. PMID 34980209 DOI: 10.1186/s13059-021-02568-9  0.418
2021 Jensen M, Tyryshkina A, Pizzo L, Smolen C, Das M, Huber E, Krishnan A, Girirajan S. Combinatorial patterns of gene expression changes contribute to variable expressivity of the developmental delay-associated 16p12.1 deletion. Genome Medicine. 13: 163. PMID 34657631 DOI: 10.1186/s13073-021-00982-z  0.293
2021 Samart K, Tuyishime P, Krishnan A, Ravi J. Reconciling multiple connectivity scores for drug repurposing. Briefings in Bioinformatics. PMID 34013329 DOI: 10.1093/bib/bbab161  0.633
2021 Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Desai I, Karthikeyan S, Gould DJ, Yennawar S, Weiner AT, Pounraja VK, ... Krishnan A, et al. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. Plos Genetics. 17: e1009112. PMID 33819264 DOI: 10.1371/journal.pgen.1009112  0.358
2021 Liu R, Krishnan A. PecanPy: a fast, efficient, and parallelized Python implementation of node2vec. Bioinformatics (Oxford, England). PMID 33760066 DOI: 10.1093/bioinformatics/btab202  0.291
2020 Mancuso CA, Canfield JL, Singla D, Krishnan A. A flexible, interpretable, and accurate approach for imputing the expression of unmeasured genes. Nucleic Acids Research. PMID 33074331 DOI: 10.1093/nar/gkaa881  0.416
2020 Liu R, Mancuso CA, Yannakopoulos A, Johnson KA, Krishnan A. Supervised-learning is an accurate method for network-based gene classification. Bioinformatics (Oxford, England). PMID 32129827 DOI: 10.1093/Bioinformatics/Btaa150  0.461
2019 Lee YS, Krishnan A, Oughtred R, Rust J, Chang CS, Ryu J, Kristensen VN, Dolinski K, Theesfeld CL, Troyanskaya OG. A Computational Framework for Genome-wide Characterization of the Human Disease Landscape. Cell Systems. PMID 30685436 DOI: 10.1016/J.Cels.2018.12.010  0.654
2018 Pizzo L, Jensen M, Polyak A, Rosenfeld JA, Mannik K, Krishnan A, McCready E, Pichon O, Le Caignec C, Van Dijck A, Pope K, Voorhoeve E, Yoon J, Stankiewicz P, Cheung SW, et al. Rare variants in the genetic background modulate cognitive and developmental phenotypes in individuals carrying disease-associated variants. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 30190612 DOI: 10.1038/S41436-018-0266-3  0.386
2018 Iyer J, Singh MD, Jensen M, Patel P, Pizzo L, Huber E, Koerselman H, Weiner AT, Lepanto P, Vadodaria K, Kubina A, Wang Q, Talbert A, Yennawar S, Badano J, ... ... Krishnan A, et al. Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11.2 deletion in Drosophila melanogaster. Nature Communications. 9: 2548. PMID 29959322 DOI: 10.1038/S41467-018-04882-6  0.465
2018 Wong AK, Krishnan A, Troyanskaya OG. GIANT 2.0: genome-scale integrated analysis of gene networks in tissues. Nucleic Acids Research. PMID 29800226 DOI: 10.1093/Nar/Gky408  0.658
2018 Rangan AV, McGrouther CC, Kelsoe J, Schork N, Stahl E, Zhu Q, Krishnan A, Yao V, Troyanskaya O, Bilaloglu S, Raghavan P, Bergen S, Jureus A, Landen M. A loop-counting method for covariate-corrected low-rank biclustering of gene-expression and genome-wide association study data. Plos Computational Biology. 14: e1006105. PMID 29758032 DOI: 10.1371/Journal.Pcbi.1006105  0.727
2017 Krishnan A, Gupta C, Ambavaram MMR, Pereira A. RECoN: Rice Environment Coexpression Network for Systems Level Analysis of Abiotic-Stress Response. Frontiers in Plant Science. 8: 1640. PMID 28979289 DOI: 10.3389/Fpls.2017.01640  0.708
2016 Krishnan A, Zhang R, Yao V, Theesfeld CL, Wong AK, Tadych A, Volfovsky N, Packer A, Lash A, Troyanskaya OG. Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder. Nature Neuroscience. PMID 27479844 DOI: 10.1038/Nn.4353  0.637
2016 Krishnan A, Taroni JN, Greene CS. Integrative Networks Illuminate Biological Factors Underlying Gene–Disease Associations Current Genetic Medicine Reports. 4: 155-162. DOI: 10.1007/S40142-016-0102-5  0.631
2015 Wong AK, Krishnan A, Yao V, Tadych A, Troyanskaya OG. IMP 2.0: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks. Nucleic Acids Research. 43: W128-33. PMID 25969450 DOI: 10.1093/nar/gkv486  0.609
2015 Goya J, Wong AK, Yao V, Krishnan A, Homilius M, Troyanskaya OG. FNTM: a server for predicting functional networks of tissues in mouse. Nucleic Acids Research. 43: W182-7. PMID 25940632 DOI: 10.1093/Nar/Gkv443  0.648
2015 Greene CS, Krishnan A, Wong AK, Ricciotti E, Zelaya RA, Himmelstein DS, Zhang R, Hartmann BM, Zaslavsky E, Sealfon SC, Chasman DI, FitzGerald GA, Dolinski K, Grosser T, Troyanskaya OG. Understanding multicellular function and disease with human tissue-specific networks. Nature Genetics. 47: 569-76. PMID 25915600 DOI: 10.1038/Ng.3259  0.724
2015 Chikina MD, Gerald CP, Li X, Ge Y, Pincas H, Nair VD, Wong AK, Krishnan A, Troyanskaya OG, Raymond D, Saunders-Pullman R, Bressman SB, Yue Z, Sealfon SC. Low-variance RNAs identify Parkinson's disease molecular signature in blood. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 813-21. PMID 25786808 DOI: 10.1002/Mds.26205  0.699
2015 Zhu Q, Wong AK, Krishnan A, Aure MR, Tadych A, Zhang R, Corney DC, Greene CS, Bongo LA, Kristensen VN, Charikar M, Li K, Troyanskaya OG. Targeted exploration and analysis of large cross-platform human transcriptomic compendia. Nature Methods. 12: 211-4, 3 p following. PMID 25581801 DOI: 10.1038/Nmeth.3249  0.721
2015 Park CY, Krishnan A, Zhu Q, Wong AK, Lee YS, Troyanskaya OG. Tissue-aware data integration approach for the inference of pathway interactions in metazoan organisms. Bioinformatics (Oxford, England). 31: 1093-101. PMID 25431329 DOI: 10.1093/Bioinformatics/Btu786  0.675
2014 Ambavaram MM, Basu S, Krishnan A, Ramegowda V, Batlang U, Rahman L, Baisakh N, Pereira A. Coordinated regulation of photosynthesis in rice increases yield and tolerance to environmental stress. Nature Communications. 5: 5302. PMID 25358745 DOI: 10.1038/Ncomms6302  0.653
2014 Ramegowda V, Basu S, Krishnan A, Pereira A. Rice GROWTH UNDER DROUGHT KINASE is required for drought tolerance and grain yield under normal and drought stress conditions. Plant Physiology. 166: 1634-45. PMID 25209982 DOI: 10.1104/Pp.114.248203  0.629
2014 Basu S, Krishnan A, Ambavaram M, Rahman L, Ramegowda V, Pereira A. Identification of genes directly regulated by a transcription factor in rice Protocol Exchange. DOI: 10.1038/Protex.2014.039  0.641
2013 Lee YS, Krishnan A, Zhu Q, Troyanskaya OG. Ontology-aware classification of tissue and cell-type signals in gene expression profiles across platforms and technologies. Bioinformatics (Oxford, England). 29: 3036-44. PMID 24037214 DOI: 10.1093/Bioinformatics/Btt529  0.689
2013 Poirel CL, Rahman A, Rodrigues RR, Krishnan A, Addesa JR, Murali TM. Reconciling differential gene expression data with molecular interaction networks. Bioinformatics (Oxford, England). 29: 622-9. PMID 23314326 DOI: 10.1093/Bioinformatics/Btt007  0.466
2012 Kakumanu A, Ambavaram MM, Klumas C, Krishnan A, Batlang U, Myers E, Grene R, Pereira A. Effects of drought on gene expression in maize reproductive and leaf meristem tissue revealed by RNA-Seq. Plant Physiology. 160: 846-67. PMID 22837360 DOI: 10.1104/Pp.112.200444  0.665
2011 Ambavaram MM, Krishnan A, Trijatmiko KR, Pereira A. Coordinated activation of cellulose and repression of lignin biosynthesis pathways in rice. Plant Physiology. 155: 916-31. PMID 21205614 DOI: 10.1104/Pp.110.168641  0.655
2011 Mohapatra SK, Krishnan A. Microarray data analysis. Methods in Molecular Biology (Clifton, N.J.). 678: 27-43. PMID 20931370 DOI: 10.1007/978-1-60761-682-5_3  0.492
2010 Harb A, Krishnan A, Ambavaram MM, Pereira A. Molecular and physiological analysis of drought stress in Arabidopsis reveals early responses leading to acclimation in plant growth. Plant Physiology. 154: 1254-71. PMID 20807999 DOI: 10.1104/Pp.110.161752  0.647
2010 Bassaganya-Riera J, Skoneczka J, Kingston DG, Krishnan A, Misyak SA, Guri AJ, Pereira A, Carter AB, Minorsky P, Tumarkin R, Hontecillas R. Mechanisms of action and medicinal applications of abscisic Acid. Current Medicinal Chemistry. 17: 467-78. PMID 20015036 DOI: 10.2174/092986710790226110  0.641
2009 Krishnan A, Guiderdoni E, An G, Hsing YI, Han CD, Lee MC, Yu SM, Upadhyaya N, Ramachandran S, Zhang Q, Sundaresan V, Hirochika H, Leung H, Pereira A. Mutant resources in rice for functional genomics of the grasses. Plant Physiology. 149: 165-70. PMID 19126710 DOI: 10.1104/Pp.108.128918  0.633
2008 Krishnan A, Pereira A. Integrative approaches for mining transcriptional regulatory programs in Arabidopsis. Briefings in Functional Genomics & Proteomics. 7: 264-74. PMID 18632743 DOI: 10.1093/Bfgp/Eln035  0.671
2007 Karaba A, Dixit S, Greco R, Aharoni A, Trijatmiko KR, Marsch-Martinez N, Krishnan A, Nataraja KN, Udayakumar M, Pereira A. Improvement of water use efficiency in rice by expression of HARDY, an Arabidopsis drought and salt tolerance gene. Proceedings of the National Academy of Sciences of the United States of America. 104: 15270-5. PMID 17881564 DOI: 10.1073/Pnas.0707294104  0.647
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