Shangzhong Li, Ph.D. - Publications

Affiliations: 
2012-2019 Bioengineering University of California, San Diego, La Jolla, CA 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kellman BP, Baghdassarian HM, Pramparo T, Shamie I, Gazestani V, Begzati A, Li S, Nalabolu S, Murray S, Lopez L, Pierce K, Courchesne E, Lewis NE. Multiple freeze-thaw cycles lead to a loss of consistency in poly(A)-enriched RNA sequencing. Bmc Genomics. 22: 69. PMID 33478392 DOI: 10.1186/s12864-021-07381-z  0.6
2020 Fouladiha H, Marashi SA, Li S, Li Z, Masson HO, Vaziri B, Lewis NE. Systematically gap-filling the genome-scale metabolic model of CHO cells. Biotechnology Letters. PMID 33040240 DOI: 10.1007/s10529-020-03021-w  0.6
2020 Joshi CJ, Schinn SM, Richelle A, Shamie I, O'Rourke EJ, Lewis NE. StanDep: Capturing transcriptomic variability improves context-specific metabolic models. Plos Computational Biology. 16: e1007764. PMID 32396573 DOI: 10.1371/Journal.Pcbi.1007764  0.48
2020 Courchesne E, Gazestani VH, Lewis NE. Prenatal Origins of ASD: The When, What, and How of ASD Development. Trends in Neurosciences. 43: 326-342. PMID 32353336 DOI: 10.1016/J.Tins.2020.03.005  0.36
2020 Gutierrez JM, Feizi A, Li S, Kallehauge TB, Hefzi H, Grav LM, Ley D, Baycin Hizal D, Betenbaugh MJ, Voldborg B, Faustrup Kildegaard H, Min Lee G, Palsson BO, Nielsen J, Lewis NE. Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion. Nature Communications. 11: 68. PMID 31896772 DOI: 10.1038/S41467-019-13867-Y  0.6
2019 Gazestani VH, Lewis NE. From Genotype to Phenotype: Augmenting Deep Learning with Networks and Systems Biology. Current Opinion in Systems Biology. 15: 68-73. PMID 31777764 DOI: 10.1016/J.Coisb.2019.04.001  0.32
2019 Julie la Cour Karottki K, Hefzi H, Xiong K, Shamie I, Hansen AH, Li S, Pedersen LE, Li S, Lee JS, Lee GM, Kildegaard HF, Lewis NE. Awakening dormant glycosyltransferases in CHO cells with CRISPRa. Biotechnology and Bioengineering. PMID 31631317 DOI: 10.1002/Bit.27199  0.6
2019 Richelle A, Joshi C, Lewis NE. Assessing key decisions for transcriptomic data integration in biochemical networks. Plos Computational Biology. 15: e1007185. PMID 31323017 DOI: 10.1371/Journal.Pcbi.1007185  0.48
2019 Chiang AWT, Li S, Kellman BP, Chattopadhyay G, Zhang Y, Kuo CC, Gutierrez JM, Ghazi F, Schmeisser H, Ménard P, Bjørn SP, Voldborg BG, Rosenberg AS, Puig M, Lewis NE. Combating viral contaminants in CHO cells by engineering innate immunity. Scientific Reports. 9: 8827. PMID 31222165 DOI: 10.1038/S41598-019-45126-X  0.6
2019 Li S, Cha SW, Hefner K, Hizal DB, Bowen MA, Chaerkady R, Cole RN, Tejwani V, Kaushik P, Henry M, Meleady P, Sharfstein ST, Betenbaugh MJ, Bafna V, Lewis NE. Proteogenomic annotation of the Chinese hamster reveals extensive novel translation events and endogenous retroviral elements. Journal of Proteome Research. PMID 31020842 DOI: 10.1021/Acs.Jproteome.8B00935  0.6
2019 Richelle A, Chiang AWT, Kuo CC, Lewis NE. Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions. Plos Computational Biology. 15: e1006867. PMID 30986217 DOI: 10.1371/Journal.Pcbi.1006867  0.48
2019 Xiong K, Marquart KF, Karottki KJC, Li S, Shamie I, Lee JS, Gerling S, Yeo NC, Chavez A, Lee GM, Lewis NE, Kildegaard HF. Reduced Apoptosis in Chinese Hamster Ovary Cells via Optimized CRISPR Interference. Biotechnology and Bioengineering. PMID 30883679 DOI: 10.1002/Bit.26969  0.6
2019 Pristovsek N, Nallapereddy S, Grav LM, Hefzi H, Lewis NE, Rugbjerg P, Hansen HG, Lee GM, Andersen MR, Kildegaard HF. Systematic Evaluation of Site-Specific Recombinant Gene Expression for Programmable Mammalian Cell Engineering. Acs Synthetic Biology. PMID 30807689 DOI: 10.1021/Acssynbio.8B00453  0.4
2018 Brunk E, Chang RL, Xia J, Hefzi H, Yurkovich JT, Kim D, Buckmiller E, Wang HH, Cho BK, Yang C, Palsson BO, Church GM, Lewis NE. Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301795 DOI: 10.1073/Pnas.1811971115  0.44
2018 Rupp O, MacDonald ML, Li S, Dhiman H, Polson S, Griep S, Heffner K, Hernandez I, Brinkrolf K, Jadhav V, Samoudi M, Hao H, Kingham B, Goesmann A, Betenbaugh MJ, et al. A reference genome of the Chinese hamster based on a hybrid assembly strategy. Biotechnology and Bioengineering. PMID 29704459 DOI: 10.1002/Bit.26722  0.6
2018 Abdel-Haleem AM, Hefzi H, Mineta K, Gao X, Gojobori T, Palsson BO, Lewis NE, Jamshidi N. Functional interrogation of Plasmodium genus metabolism identifies species- and stage-specific differences in nutrient essentiality and drug targeting. Plos Computational Biology. 14: e1005895. PMID 29300748 DOI: 10.1371/Journal.Pcbi.1005895  0.4
2017 Kuo CC, Chiang AW, Shamie I, Samoudi M, Gutierrez JM, Lewis NE. The emerging role of systems biology for engineering protein production in CHO cells. Current Opinion in Biotechnology. 51: 64-69. PMID 29223005 DOI: 10.1016/J.Copbio.2017.11.015  0.32
2017 Abdel-Haleem AM, Lewis NE, Jamshidi N, Mineta K, Gao X, Gojobori T. The Emerging Facets of Non-Cancerous Warburg Effect. Frontiers in Endocrinology. 8: 279. PMID 29109698 DOI: 10.3389/Fendo.2017.00279  0.32
2017 Richelle A, Lewis NE. Improvements in protein production in mammalian cells from targeted metabolic engineering. Current Opinion in Systems Biology. 6: 1-6. PMID 29104947 DOI: 10.1016/J.Coisb.2017.05.019  0.64
2017 Opdam S, Richelle A, Kellman B, Li S, Zielinski DC, Lewis NE. A Systematic Evaluation of Methods for Tailoring Genome-Scale Metabolic Models. Cell Systems. PMID 28215528 DOI: 10.1016/J.Cels.2017.01.010  0.6
2017 Kallehauge TB, Li S, Pedersen LE, Ha TK, Ley D, Andersen MR, Kildegaard HF, Lee GM, Lewis NE. Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion. Scientific Reports. 7: 40388. PMID 28091612 DOI: 10.1038/Srep40388  0.6
2017 van Wijk XM, Döhrmann S, Hallström BM, Li S, Voldborg BG, Meng BX, McKee KK, van Kuppevelt TH, Yurchenco PD, Palsson BO, Lewis NE, Nizet V, Esko JD. Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion. Mbio. 8. PMID 28074024 DOI: 10.1128/Mbio.02128-16  0.6
2016 Spahn PN, Hansen AH, Kol S, Voldborg BG, Lewis NE. Predictive glycoengineering of biosimilars using a Markov chain glycosylation model. Biotechnology Journal. PMID 27860290 DOI: 10.1002/Biot.201600489  0.36
2016 Chiang AW, Li S, Spahn PN, Richelle A, Kuo CC, Samoudi M, Lewis NE. Modulating carbohydrate-protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology. Current Opinion in Structural Biology. 40: 104-111. PMID 27639240 DOI: 10.1016/J.Sbi.2016.08.008  0.6
2016 Swainston N, Smallbone K, Hefzi H, Dobson PD, Brewer J, Hanscho M, Zielinski DC, Ang KS, Gardiner NJ, Gutierrez JM, Kyriakopoulos S, Lakshmanan M, Li S, Liu JK, Martínez VS, et al. Recon 2.2: from reconstruction to model of human metabolism. Metabolomics : Official Journal of the Metabolomic Society. 12: 109. PMID 27358602 DOI: 10.1007/S11306-016-1051-4  0.6
2016 Golabgir A, Gutierrez JM, Hefzi H, Li S, Palsson BO, Herwig C, Lewis NE. Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow. Biotechnology Advances. PMID 26948029 DOI: 10.1016/J.Biotechadv.2016.02.011  0.6
2015 Spahn PN, Hansen AH, Hansen HG, Arnsdorf J, Kildegaard HF, Lewis NE. A Markov chain model for N-linked protein glycosylation - towards a low-parameter tool for model-driven glycoengineering. Metabolic Engineering. PMID 26537759 DOI: 10.1016/J.Ymben.2015.10.007  0.48
2015 King ZA, Lu J, Dräger A, Miller P, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, Lewis NE. BiGG Models: A platform for integrating, standardizing and sharing genome-scale models. Nucleic Acids Research. PMID 26476456 DOI: 10.1093/Nar/Gkv1049  0.48
2015 King ZA, Dräger A, Ebrahim A, Sonnenschein N, Lewis NE, Palsson BO. Escher: A Web Application for Building, Sharing, and Embedding Data-Rich Visualizations of Biological Pathways. Plos Computational Biology. 11: e1004321. PMID 26313928 DOI: 10.1371/Journal.Pcbi.1004321  0.32
2015 Gutierrez JM, Lewis NE. Optimizing eukaryotic cell hosts for protein production through systems biotechnology and genome-scale modeling. Biotechnology Journal. PMID 26099571 DOI: 10.1002/Biot.201400647  0.44
2015 Lee JS, Grav LM, Lewis NE, Faustrup Kildegaard H. CRISPR/Cas9-mediated genome engineering of CHO cell factories: Application and perspectives. Biotechnology Journal. 10: 979-94. PMID 26058577 DOI: 10.1002/Biot.201500082  0.32
2014 Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM. Rapid neurogenesis through transcriptional activation in human stem cells. Molecular Systems Biology. 10: 760. PMID 25403753 DOI: 10.15252/Msb.20145508  0.6
2014 Spahn PN, Lewis NE. Systems glycobiology for glycoengineering. Current Opinion in Biotechnology. 30: 218-24. PMID 25202878 DOI: 10.1016/J.Copbio.2014.08.004  0.92
2014 Bordbar A, Nagarajan H, Lewis NE, Latif H, Ebrahim A, Federowicz S, Schellenberger J, Palsson BO. Minimal metabolic pathway structure is consistent with associated biomolecular interactions. Molecular Systems Biology. 10: 737. PMID 24987116 DOI: 10.15252/Msb.20145243  0.32
2014 Robasky K, Lewis NE, Church GM. The role of replicates for error mitigation in next-generation sequencing. Nature Reviews. Genetics. 15: 56-62. PMID 24322726 DOI: 10.1038/Nrg3655  0.44
2013 Lewis NE, Abdel-Haleem AM. The evolution of genome-scale models of cancer metabolism. Frontiers in Physiology. 4: 237. PMID 24027532 DOI: 10.3389/Fphys.2013.00237  0.6
2013 Kildegaard HF, Baycin-Hizal D, Lewis NE, Betenbaugh MJ. The emerging CHO systems biology era: harnessing the 'omics revolution for biotechnology. Current Opinion in Biotechnology. 24: 1102-7. PMID 23523260 DOI: 10.1016/J.Copbio.2013.02.007  0.4
2013 Hyduke DR, Lewis NE, Palsson BØ. Analysis of omics data with genome-scale models of metabolism. Molecular Biosystems. 9: 167-74. PMID 23247105 DOI: 10.1039/C2Mb25453K  0.52
2013 Hefzi H, Palsson BO, Lewis NE. Reconstruction of Genome-Scale Metabolic Networks Handbook of Systems Biology. 229-250. DOI: 10.1016/B978-0-12-385944-0.00012-5  0.84
2012 Lewis NE, Nagarajan H, Palsson BO. Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods. Nature Reviews. Microbiology. 10: 291-305. PMID 22367118 DOI: 10.1038/Nrmicro2737  0.56
2011 Conrad TM, Lewis NE, Palsson BØ. Microbial laboratory evolution in the era of genome-scale science. Molecular Systems Biology. 7: 509. PMID 21734648 DOI: 10.1038/Msb.2011.42  0.64
2011 Schellenberger J, Lewis NE, Palsson BØ. Elimination of thermodynamically infeasible loops in steady-state metabolic models. Biophysical Journal. 100: 544-53. PMID 21281568 DOI: 10.1016/J.Bpj.2010.12.3707  0.32
2010 Portnoy VA, Scott DA, Lewis NE, Tarasova Y, Osterman AL, Palsson BØ. Deletion of genes encoding cytochrome oxidases and quinol monooxygenase blocks the aerobic-anaerobic shift in Escherichia coli K-12 MG1655. Applied and Environmental Microbiology. 76: 6529-40. PMID 20709841 DOI: 10.1128/Aem.01178-10  0.36
2009 Lewis NE, Cho BK, Knight EM, Palsson BO. Gene expression profiling and the use of genome-scale in silico models of Escherichia coli for analysis: providing context for content. Journal of Bacteriology. 191: 3437-44. PMID 19363119 DOI: 10.1128/Jb.00034-09  0.48
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