| Year |
Citation |
Score |
| 2018 |
Zhang X, Hou Y, Peng C, Wang C, Wang X, Liang Z, Lu J, Chen B, Dai J, Liu B, Cui M. Oligoethyleneoxy-modified 99mTc-labeled beta amyloid imaging probes with improved brain pharmacokinetics for single-photon emission computed tomography. Journal of Medicinal Chemistry. PMID 29304285 DOI: 10.1021/Acs.Jmedchem.7B01834 |
0.49 |
|
| 2016 |
Fu H, Peng C, Liang Z, Dai J, Liu B, Cui M. In vivo near-infrared and Cerenkov luminescence imaging of amyloid-β deposits in the brain: a fluorinated small molecule used for dual-modality imaging. Chemical Communications (Cambridge, England). PMID 27722543 DOI: 10.1039/C6Cc06995A |
0.439 |
|
| 2016 |
Zhang X, Yu P, Yang Y, Hou Y, Peng C, Liang Z, Lu J, Chen B, Dai J, Liu B, Cui M. 99mTc-labeled 2-arylbenzothiazoles: Aβ imaging probes with favorable brain pharmacokinetics for single-photon emission computed tomography. Bioconjugate Chemistry. PMID 27668687 DOI: 10.1021/Acs.Bioconjchem.6B00444 |
0.485 |
|
| 2016 |
Jia J, Zhou K, Dai J, Liu B, Cui M. 2-Arylbenzothiazoles labeled with [CpRe/(99m)Tc(CO)3] and evaluated as β-amyloid imaging probes. European Journal of Medicinal Chemistry. 124: 763-772. PMID 27639367 DOI: 10.1016/J.Ejmech.2016.09.001 |
0.494 |
|
| 2016 |
Jia J, Song J, Dai J, Liu B, Cui M. Optically Pure Diphenoxy Derivatives as More Flexible Probes for β-Amyloid Plaques. Acs Chemical Neuroscience. PMID 27337293 DOI: 10.1021/Acschemneuro.6B00155 |
0.45 |
|
| 2016 |
Li D, Chen Y, Wang X, Deuther-Conrad W, Chen X, Jia B, Dong C, Steinbach J, Brust P, Liu B, Jia H. 99mTc-cyclopentadienyl Tricarbonyl Chelate-labeled Compounds as Selective Sigma-2 Receptor Ligands for Tumor Imaging. Journal of Medicinal Chemistry. PMID 26741785 DOI: 10.1021/Acs.Jmedchem.5B01378 |
0.351 |
|
| 2016 |
Cui X, Zhang X, Peng C, Dai J, Liu B, Cui M. Radiolabeled pyridinyl analogues of dibenzylideneacetone as β-amyloid imaging probes Rsc Advances. 6: 44646-44654. DOI: 10.1039/C6Ra05168E |
0.408 |
|
| 2015 |
Fu H, Tu P, Zhao L, Dai J, Liu B, Cui M. Amyloid-β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation and in Vivo Imaging. Analytical Chemistry. PMID 26717442 DOI: 10.1021/Acs.Analchem.5B04441 |
0.46 |
|
| 2015 |
Yang Y, Fu H, Cui M, Peng C, Liang Z, Dai J, Zhang Z, Lin C, Liu B. Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography. European Journal of Medicinal Chemistry. 104: 86-96. PMID 26435514 DOI: 10.1016/J.Ejmech.2015.09.028 |
0.481 |
|
| 2015 |
Fu H, Cui M, Zhao L, Tu P, Zhou K, Dai J, Liu B. Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-β Plaques in Alzheimer's Disease. Journal of Medicinal Chemistry. 58: 6972-83. PMID 26262759 DOI: 10.1021/Acs.Jmedchem.5B00861 |
0.454 |
|
| 2015 |
Yang Y, Zhang X, Cui M, Zhang J, Guo Z, Li Y, Zhang X, Dai J, Liu B. Preliminary Characterization and In Vivo Studies of Structurally Identical (18)F- and (125)I-Labeled Benzyloxybenzenes for PET/SPECT Imaging of β-Amyloid Plaques. Scientific Reports. 5: 12084. PMID 26170205 DOI: 10.1038/Srep12084 |
0.404 |
|
| 2015 |
Zhou K, Fu H, Feng L, Cui M, Dai J, Liu B. The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques. Chemical Communications (Cambridge, England). PMID 26103205 DOI: 10.1039/C5Cc03662C |
0.449 |
|
| 2015 |
Xie F, Bergmann R, Kniess T, Deuther-Conrad W, Mamat C, Neuber C, Liu B, Steinbach J, Brust P, Pietzsch J, Jia H. 18F-labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a Sigma-1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent. Journal of Medicinal Chemistry. PMID 26090686 DOI: 10.1021/Acs.Jmedchem.5B00593 |
0.398 |
|
| 2015 |
Jia J, Cui M, Dai J, Liu B. (99m)Tc(CO)3-Labeled Benzothiazole Derivatives Preferentially Bind Cerebrovascular Amyloid: Potential Use as Imaging Agents for Cerebral Amyloid Angiopathy. Molecular Pharmaceutics. PMID 26065726 DOI: 10.1021/Acs.Molpharmaceut.5B00209 |
0.452 |
|
| 2015 |
Jia J, Cui M, Dai J, Liu B. 2-Phenylbenzothiazole conjugated with cyclopentadienyl tricarbonyl [CpM(CO)3] (M = Re, (99m)Tc) complexes as potential imaging probes for β-amyloid plaques. Dalton Transactions (Cambridge, England : 2003). 44: 6406-15. PMID 25747395 DOI: 10.1039/C5Dt00023H |
0.495 |
|
| 2015 |
Wang X, Cui M, Jia J, Liu B. (99m)Tc-labeled-2-arylbenzoxazole derivatives as potential Aβ imaging probes for single-photon emission computed tomography. European Journal of Medicinal Chemistry. 89: 331-9. PMID 25462249 DOI: 10.1016/J.Ejmech.2014.10.046 |
0.478 |
|
| 2015 |
Xie F, Kniess T, Neuber C, Deuther-Conrad W, Mamat C, Lieberman BP, Liu B, Mach RH, Brust P, Steinbach J, Pietzsch J, Jia H. Novel indole-based sigma-2 receptor ligands: synthesis, structure-affinity relationship and antiproliferative activity Medchemcomm. 6: 1093-1103. DOI: 10.1039/C5Md00079C |
0.328 |
|
| 2014 |
Chen YY, Wang X, Zhang JM, Deuther-Conrad W, Zhang XJ, Huang Y, Li Y, Ye JJ, Cui MC, Steinbach J, Brust P, Liu BL, Jia HM. Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent. Bioorganic & Medicinal Chemistry. 22: 5270-8. PMID 25189691 DOI: 10.1016/J.Bmc.2014.08.003 |
0.417 |
|
| 2014 |
Fu H, Cui M, Tu P, Pan Z, Liu B. Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes. Chemical Communications (Cambridge, England). 50: 11875-8. PMID 25156492 DOI: 10.1039/C4Cc04907A |
0.43 |
|
| 2014 |
Wang X, Li D, Deuther-Conrad W, Lu J, Xie Y, Jia B, Cui M, Steinbach J, Brust P, Liu B, Jia H. Novel cyclopentadienyl tricarbonyl (99m)tc complexes containing 1-piperonylpiperazine moiety: potential imaging probes for sigma-1 receptors. Journal of Medicinal Chemistry. 57: 7113-25. PMID 25073047 DOI: 10.1021/Jm5009488 |
0.429 |
|
| 2014 |
Li Z, Cui M, Zhang J, Dai J, Zhang X, Chen P, Jia H, Liu B. Novel ¹⁸F-labeled dibenzylideneacetone derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques. European Journal of Medicinal Chemistry. 84: 628-38. PMID 25063945 DOI: 10.1016/J.Ejmech.2014.07.070 |
0.489 |
|
| 2014 |
Yang Y, Cui M, Zhang X, Dai J, Zhang Z, Lin C, Guo Y, Liu B. Radioiodinated benzyloxybenzene derivatives: A class of flexible ligands target to β-amyloid plaques in Alzheimer's brains Journal of Medicinal Chemistry. 57: 6030-6042. PMID 24936678 DOI: 10.1021/Jm5004396 |
0.449 |
|
| 2014 |
Cui M, Ono M, Watanabe H, Kimura H, Liu B, Saji H. Smart near-infrared fluorescence probes with donor-acceptor structure for in vivo detection of β-amyloid deposits. Journal of the American Chemical Society. 136: 3388-94. PMID 24555862 DOI: 10.1021/Ja4052922 |
0.458 |
|
| 2014 |
Jia J, Cui M, Dai J, Wang X, Ding Y, Jia H, Liu B. 99mTc-labeled benzothiazole and stilbene derivatives as imaging agents for Aβ plaques in cerebral amyloid angiopathy Medchemcomm. 5: 153-158. DOI: 10.1039/C3Md00195D |
0.45 |
|
| 2014 |
Jia J, Cui M, Liu B. [CpM(CO)3] (M = Re, 99mTc) labeled phenylbenzothiazoles as imaging agents for Aβ plaques Nuclear Medicine and Biology. 41: 614. DOI: 10.1016/J.Nucmedbio.2014.05.057 |
0.382 |
|
| 2014 |
Jia J, Cui M, Liu B. 99mTc(CO)3-labeled 2-phenylbenzothiazoles as Aβ imaging agents for the detection of CAA Nuclear Medicine and Biology. 41: 620-621. DOI: 10.1016/J.Nucmedbio.2014.05.056 |
0.362 |
|
| 2013 |
Fu H, Yu L, Cui M, Zhang J, Zhang X, Li Z, Wang X, Jia J, Yang Y, Yu P, Jia H, Liu B. Synthesis and biological evaluation of 18F-labled 2-phenylindole derivatives as PET imaging probes for β-amyloid plaques. Bioorganic & Medicinal Chemistry. 21: 3708-14. PMID 23673220 DOI: 10.1016/J.Bmc.2013.04.028 |
0.482 |
|
| 2013 |
Yang Y, Cui M, Jin B, Wang X, Li Z, Yu P, Jia J, Fu H, Jia H, Liu B. (99m)Tc-labeled dibenzylideneacetone derivatives as potential SPECT probes for in vivo imaging of β-amyloid plaque. European Journal of Medicinal Chemistry. 64: 90-8. PMID 23644192 DOI: 10.1016/J.Ejmech.2013.03.057 |
0.46 |
|
| 2013 |
Li Y, Wang X, Zhang J, Deuther-Conrad W, Xie F, Zhang X, Liu J, Qiao J, Cui M, Steinbach J, Brust P, Liu B, Jia H. Synthesis and evaluation of novel (18)F-labeled spirocyclic piperidine derivatives as σ1 receptor ligands for positron emission tomography imaging. Journal of Medicinal Chemistry. 56: 3478-91. PMID 23566245 DOI: 10.1021/Jm301734G |
0.431 |
|
| 2013 |
Li Z, Cui M, Dai J, Wang X, Yu P, Yang Y, Jia J, Fu H, Ono M, Jia H, Saji H, Liu B. Novel cyclopentadienyl tricarbonyl complexes of (99m)Tc mimicking chalcone as potential single-photon emission computed tomography imaging probes for β-amyloid plaques in brain. Journal of Medicinal Chemistry. 56: 471-82. PMID 23240831 DOI: 10.1021/Jm3014184 |
0.493 |
|
| 2013 |
Wang X, Li Y, Deuther-Conrad W, Xie F, Chen X, Cui MC, Zhang XJ, Zhang JM, Steinbach J, Brust P, Liu BL, Jia HM. Synthesis and biological evaluation of ¹â¸F labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging. Bioorganic & Medicinal Chemistry. 21: 215-22. PMID 23199475 DOI: 10.1016/J.Bmc.2012.10.038 |
0.412 |
|
| 2012 |
Yu P, Cui M, Wang X, Zhang X, Li Z, Yang Y, Jia J, Zhang J, Ono M, Saji H, Jia H, Liu B. ¹⁸F-labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques. European Journal of Medicinal Chemistry. 57: 51-8. PMID 23047223 DOI: 10.1016/J.Ejmech.2012.08.031 |
0.437 |
|
| 2012 |
Chen X, Cui MC, Deuther-Conrad W, Tu YF, Ma T, Xie Y, Jia B, Li Y, Xie F, Wang X, Steinbach J, Brust P, Liu BL, Jia HM. Synthesis and biological evaluation of a novel 99mTc cyclopentadienyl tricarbonyl complex ([(Cp-R)99mTc(CO)3]) for sigma-2 receptor tumor imaging. Bioorganic & Medicinal Chemistry Letters. 22: 6352-7. PMID 22995625 DOI: 10.1016/J.Bmcl.2012.08.083 |
0.415 |
|
| 2012 |
Cui M, Wang X, Yu P, Zhang J, Li Z, Zhang X, Yang Y, Ono M, Jia H, Saji H, Liu B. Synthesis and evaluation of novel ¹⁸F labeled 2-pyridinylbenzoxazole and 2-pyridinylbenzothiazole derivatives as ligands for positron emission tomography (PET) imaging of β-amyloid plaques. Journal of Medicinal Chemistry. 55: 9283-96. PMID 22974116 DOI: 10.1021/Jm300973K |
0.483 |
|
| 2012 |
Cui M, Ono M, Kimura H, Ueda M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Liu B, Saji H. Novel ¹⁸F-labeled benzoxazole derivatives as potential positron emission tomography probes for imaging of cerebral β-amyloid plaques in Alzheimer's disease. Journal of Medicinal Chemistry. 55: 9136-45. PMID 22690944 DOI: 10.1021/Jm300251N |
0.439 |
|
| 2012 |
Wang X, Cui M, Yu P, Li Z, Yang Y, Jia H, Liu B. Synthesis and biological evaluation of novel technetium-99m labeled phenylbenzoxazole derivatives as potential imaging probes for β-amyloid plaques in brain. Bioorganic & Medicinal Chemistry Letters. 22: 4327-31. PMID 22652052 DOI: 10.1016/J.Bmcl.2012.05.010 |
0.478 |
|
| 2012 |
Yang Y, Jia HM, Liu BL. (E)-5-styryl-1H-indole and (E)-6-styrylquinoline derivatives serve as probes for β-amyloid plaques. Molecules (Basel, Switzerland). 17: 4252-65. PMID 22491675 DOI: 10.3390/molecules17044252 |
0.376 |
|
| 2012 |
Mou T, Zhao Z, Fang W, Peng C, Guo F, Liu B, Ma Y, Zhang X. Synthesis and preliminary evaluation of 18F-labeled pyridaben analogues for myocardial perfusion imaging with PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 472-9. PMID 22302832 DOI: 10.2967/Jnumed.111.088096 |
0.321 |
|
| 2011 |
Yang Y, Duan XH, Deng JY, Jin B, Jia HM, Liu BL. Novel imaging agents for β-amyloid plaque based on the N-benzoylindole core. Bioorganic & Medicinal Chemistry Letters. 21: 5594-7. PMID 21802289 DOI: 10.1016/J.Bmcl.2011.06.077 |
0.509 |
|
| 2011 |
Cui M, Ono M, Kimura H, Liu B, Saji H. Synthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for β-amyloid plaques. Bioorganic & Medicinal Chemistry. 19: 4148-53. PMID 21622003 DOI: 10.1016/J.Bmc.2011.04.049 |
0.461 |
|
| 2011 |
Yang W, Mou T, Shao G, Wang F, Zhang X, Liu B. Copolymer-based hepatocyte asialoglycoprotein receptor targeting agent for SPECT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 978-85. PMID 21571805 DOI: 10.2967/Jnumed.110.085167 |
0.302 |
|
| 2011 |
Cui M, Li Z, Tang R, Jia H, Liu B. Novel (E)-5-styryl-2,2′-bithiophene derivatives as ligands for β-amyloid plaques European Journal of Medicinal Chemistry. 46: 2908-2916. PMID 21531050 DOI: 10.1016/J.Ejmech.2011.04.015 |
0.449 |
|
| 2011 |
Cui M, Ono M, Kimura H, Kawashima H, Liu BL, Saji H. Radioiodinated benzimidazole derivatives as single photon emission computed tomography probes for imaging of β-amyloid plaques in Alzheimer's disease. Nuclear Medicine and Biology. 38: 313-20. PMID 21492779 DOI: 10.1016/j.nucmedbio.2010.09.012 |
0.384 |
|
| 2011 |
Li ZJ, Ren HY, Cui MC, Deuther-Conrad W, Tang RK, Steinbach J, Brust P, Liu BL, Jia HM. Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging. Bioorganic & Medicinal Chemistry. 19: 2911-7. PMID 21481592 DOI: 10.1016/J.Bmc.2011.03.037 |
0.379 |
|
| 2011 |
Cui M, Ono M, Kimura H, Liu B, Saji H. Synthesis and structure-affinity relationships of novel dibenzylideneacetone derivatives as probes for β-amyloid plaques. Journal of Medicinal Chemistry. 54: 2225-40. PMID 21417461 DOI: 10.1021/Jm101404K |
0.486 |
|
| 2011 |
Cui M, Tang R, Li Z, Ren H, Liu B. 99mTc- and Re-labeled 6-dialkylamino-2-naphthylethylidene derivatives as imaging probes for β-amyloid plaques. Bioorganic & Medicinal Chemistry Letters. 21: 1064-1068. PMID 21216146 DOI: 10.1016/J.Bmcl.2010.11.096 |
0.5 |
|
| 2011 |
Cui M, Ono M, Kimura H, Liu BL, Saji H. Synthesis and biological evaluation of indole-chalcone derivatives as β-amyloid imaging probe. Bioorganic & Medicinal Chemistry Letters. 21: 980-2. PMID 21216142 DOI: 10.1016/j.bmcl.2010.12.045 |
0.409 |
|
| 2010 |
Yang W, Mou T, Guo W, Jing H, Peng C, Zhang X, Ma Y, Liu B. Fluorine-18 labeled galactosylated chitosan for asialoglycoprotein-receptor-mediated hepatocyte imaging. Bioorganic & Medicinal Chemistry Letters. 20: 4840-4. PMID 20634070 DOI: 10.1016/J.Bmcl.2010.06.106 |
0.365 |
|
| 2010 |
Cui MC, Li ZJ, Tang RK, Liu BL. Synthesis and evaluation of novel benzothiazole derivatives based on the bithiophene structure as potential radiotracers for beta-amyloid plaques in Alzheimer's disease. Bioorganic & Medicinal Chemistry. 18: 2777-84. PMID 20211565 DOI: 10.1016/J.Bmc.2010.02.002 |
0.497 |
|
| 2010 |
Duan XH, Qiao JP, Yang Y, Cui MC, Zhou JN, Liu BL. Novel anilinophthalimide derivatives as potential probes for beta-amyloid plaque in the brain. Bioorganic & Medicinal Chemistry. 18: 1337-43. PMID 20036557 DOI: 10.1016/J.Bmc.2009.12.023 |
0.444 |
|
| 2010 |
Yu L, Scheunemann M, Deuther-Conrad W, Hiller A, Fischer S, Sorger D, Sabri O, Jia H, Steinbach J, Brust P, Liu B. Novel Indole Derivatives as Potential Imaging Agents for Alzheimer's Disease Bulletin of the Korean Chemical Society. 31: 177-180. DOI: 10.5012/Bkcs.2010.31.01.177 |
0.333 |
|
| 2010 |
Chen R, Li Y, Zhang Q, Jia H, Deuther-Conrad W, Schepmann D, Steinbach J, Brust P, Wünsch B, Liu B. Synthesis and biological evaluation of a radioiodinated spiropiperidine ligand as a potential σ1 receptor imaging agent Journal of Labelled Compounds and Radiopharmaceuticals. 53: 569-574. DOI: 10.1002/Jlcr.1777 |
0.396 |
|
| 2008 |
Guo Y, Chen X, Jia H, Ji X, Liu B. Synthesis and biological evaluation of one novel technetium-99m-labeled nitroquipazine derivative as an imaging agent for serotonin transporter Applied Radiation and Isotopes. 66: 1804-1809. PMID 18684634 DOI: 10.1016/J.Apradiso.2008.06.009 |
0.416 |
|
| 2008 |
Chen X, Yu P, Zhang L, Liu B. Synthesis and biological evaluation of 99mTc, Re-monoamine-monoamide conjugated to 2-(4-aminophenyl)benzothiazole as potential probes for beta-amyloid plaques in the brain. Bioorganic & Medicinal Chemistry Letters. 18: 1442-5. PMID 18191400 DOI: 10.1016/J.Bmcl.2007.12.071 |
0.461 |
|
| 2008 |
Chen X, Guo Y, Zhang Q, Hao G, Jia H, Liu B. Preparation and biological evaluation of 99mTc-CO-MIBI as myocardial perfusion imaging agent Journal of Organometallic Chemistry. 693: 1822-1828. DOI: 10.1016/J.Jorganchem.2008.02.006 |
0.31 |
|
| 2008 |
Duan X, Liu B. Aβ-binding molecules: Possible application as imaging probes and as anti-aggregation agents Science China-Chemistry. 51: 801-807. DOI: 10.1007/S11426-008-0075-7 |
0.422 |
|
| 2008 |
Guo Y, Chen X, Jia H, Deuther-Conrad W, Brust P, Steinbach J, Vercouillie J, Liu B. Synthesis and in vitro evaluation of new diphenyl ether derivatives as serotonin transporter ligands Science China-Chemistry. 51: 457-463. DOI: 10.1007/S11426-008-0007-6 |
0.355 |
|
| 2007 |
Hao G, Zang J, Liu B. Preparation and biodistribution of novel 99mTc(CO)3-CNR complexes for myocardial imaging Journal of Labelled Compounds and Radiopharmaceuticals. 50: 13-18. DOI: 10.1002/Jlcr.1151 |
0.324 |
|
| 2006 |
Chen X, Li L, Liu F, Liu B. Synthesis and biological evaluation of technetium-99m-labeled deoxyglucose derivatives as imaging agents for tumor. Bioorganic & Medicinal Chemistry Letters. 16: 5503-6. PMID 16931003 DOI: 10.1016/J.Bmcl.2006.08.050 |
0.32 |
|
| 2006 |
Fan C, Jia H, Deuther-Conrad W, Brust P, Steinbach J, Liu B. Novel 99m Tc labeled σ receptor ligand as a potential tumor imaging agent Science China-Chemistry. 49: 169-176. DOI: 10.1007/S11426-006-0169-Z |
0.36 |
|
| 1999 |
Miao Y, Liu B. Synthesis of new N2S ligands, preparation of 99mTc complexes and their preliminary biodistribution in mice Journal of Labelled Compounds and Radiopharmaceuticals. 42: 629-640. DOI: 10.1002/(Sici)1099-1344(199907)42:7<629::Aid-Jlcr225>3.0.Co;2-Z |
0.34 |
|
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