| Year |
Citation |
Score |
| 2022 |
Biener-Ramanujan E, Rosier F, Coetzee SG, McGovern DDP, Hazelett D, Targan SR, Gonsky R. Diagnostic and therapeutic potential of RNASET2 in Crohn's disease: Disease-risk polymorphism modulates allelic-imbalance in expression and circulating protein levels and recombinant-RNASET2 attenuates pro-inflammatory cytokine secretion. Frontiers in Immunology. 13: 999155. PMID 36466822 DOI: 10.3389/fimmu.2022.999155 |
0.327 |
|
| 2021 |
Estrada HQ, Patel S, Rabizadeh S, Casero D, Targan SR, Barrett RJ. Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells. Inflammatory Bowel Diseases. PMID 34918082 DOI: 10.1093/ibd/izab292 |
0.66 |
|
| 2020 |
Workman MJ, Troisi E, Targan SR, Svendsen CN, Barrett RJ. Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids. International Journal of Molecular Sciences. 22. PMID 33396621 DOI: 10.3390/ijms22010288 |
0.722 |
|
| 2020 |
Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, et al. Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD. Gastroenterology. PMID 33160965 DOI: 10.1053/j.gastro.2020.10.041 |
0.354 |
|
| 2020 |
Potdar AA, Dube S, Naito T, Botwin G, Haritunians T, Li D, Yang S, Bilsborough J, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, et al. Reduced expression of COVID-19 host receptor, is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 32511625 DOI: 10.1101/2020.04.19.20070995 |
0.315 |
|
| 2020 |
Gleeson JP, Estrada HQ, Yamashita M, Svendsen CN, Targan SR, Barrett RJ. Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD. International Journal of Molecular Sciences. 21. PMID 32093254 DOI: 10.3390/Ijms21041438 |
0.804 |
|
| 2020 |
Du L, Li D, Syal G, Bonthala N, Melmed G, Targan SR, Vasiliauskas E, Ziring D, Haritunians T, Botwin GJ, Hwang L, Yang S, Rabizadeh S, Ha C, McGovern DPB. Mo1859 CLINICAL, SEROLOGIC, AND GENOMIC PREDICTORS OF RESPONSE TO USTEKINUMAB IN CROHN'S DISEASE Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33059-6 |
0.336 |
|
| 2020 |
Gonsky R, Biener-Ramanujan E, Printsev I, Kim F, McGovern DP, Bilsborough J, Targan SR. Mo1111 RNASET2 RISK VARIANT AS A NOVEL BLOOD BASED DIAGNOSTIC FOR DEFINING A SEVERE CD PATIENT POPULATION RESPONSIVE TO DIRECTED RNASET2 THERAPEUTICS Gastroenterology. 158: S-791. DOI: 10.1016/S0016-5085(20)32652-4 |
0.304 |
|
| 2020 |
Dube S, Haritunians T, Li D, Hwang L, Yang S, Targan SR, Kallman C, McGovern DPB. Su1979 NOVEL ASSOCIATIONS OF ADIPOSE TISSUE (AT) VOLUMETRIC MEASURES WITH CLINICAL, SEROLOGIC, AND GENETIC VARIABLES IN CROHN'S DISEASE (CD) AND ULCERATIVE COLITIS (UC) Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)32505-1 |
0.377 |
|
| 2020 |
Syal G, Shemtov R, Pozdnyakova V, Bonthala N, Feldman EJ, Vasiliauskas E, Zaghiyan K, Ha C, McGovern DP, Melmed G, Targan SR, Fleshner P. Su1951 PRE-POUCH ILEITIS IS A RISK FACTOR FOR CROHN'S DISEASE-LIKE COMPLICATIONS, NEED FOR INVASIVE INTERVENTIONS AND IMMUNOSUPPRESSIVE THERAPY IN UC OR IBD-U PATIENTS AFTER ILEAL-POUCH ANAL ANASTOMOSIS Gastroenterology. 158: S-717. DOI: 10.1016/S0016-5085(20)32477-X |
0.345 |
|
| 2020 |
Potdar AA, Li D, Haritunians T, Targan SR, McGovern DPB, Bilsborough J. Su1877 ENRICHMENT OF POST-TRANSLATIONAL MODIFICATIONS IN INFLAMMATORY BOWEL DISEASE Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)32404-5 |
0.394 |
|
| 2020 |
Pai Y, Shih DQ, Targan SR, Turner J, Wei SC, Yu LC. Su1097 TL1A-MEDIATED BACTERIAL TRANSCYTOSIS BY A MLCK SPLICING VARIANT CONTRIBUTES TO INFLAMMATORY BOWEL DISEASE Gastroenterology. 158: S-508. DOI: 10.1016/S0016-5085(20)31949-1 |
0.419 |
|
| 2020 |
Bonthala N, Morganstern B, Mengesha E, Landers C, Mould DR, Li D, Vasiliauskas E, Targan SR, McGovern DP, Melmed G. Sa1886 EARLY VEDOLIZUMAB TROUGH LEVELS PREDICT CLINICAL RESPONSE IN A “REAL WORLD” PROSPECTIVE COHORT OF INFLAMMATORY BOWEL DISEASE PATIENTS Gastroenterology. 158: S-465-S-466. DOI: 10.1016/S0016-5085(20)31845-X |
0.385 |
|
| 2020 |
Dube S, Li D, Haritunians T, Hwang L, Yang S, Targan SR, Kallman C, McGovern DPB. 717 Novel Associations Of Brain Morphometry With Clinical, Serologic, And Genetic Variables In Crohn'S Disease (Cd) And Ulcerative Colitis (Uc) Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)31063-5 |
0.378 |
|
| 2020 |
Ye Y, Shimodaira Y, Blackwood AY, Hamade H, Castanon S, Jacob N, Jacobs JP, Potdar AA, McGovern DPB, Targan SR, Michelsen KS. 567 Tl1A Overexpression In Cd Patients And Mice Alters Paneth Cell Biology And Intestinal Microbiota In Promoting Ileal Inflammation Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)30973-2 |
0.369 |
|
| 2019 |
Potdar AA, Li D, Haritunians T, VanDussen KL, Fiorino MF, Liu TC, Stappenbeck TS, Fleshner P, Targan SR, McGovern DPB, Bilsborough J. Ileal Gene Expression Data from Crohn's Disease Small Bowel Resections Indicate Distinct Clinical Sub-Groups. Journal of Crohn's & Colitis. PMID 30877309 DOI: 10.1093/Ecco-Jcc/Jjz021 |
0.401 |
|
| 2019 |
Limon JJ, Tang J, Li D, Wolf AJ, Michelsen KS, Funari V, Gargus M, Nguyen C, Sharma P, Maymi VI, Iliev ID, Skalski JH, Brown J, Landers C, Borneman J, ... ... Targan SR, et al. Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models. Cell Host & Microbe. PMID 30850233 DOI: 10.1016/J.Chom.2019.01.007 |
0.477 |
|
| 2019 |
Tsuda M, Hamade H, Thomas LS, Salumbides BC, Potdar AA, Wong MH, Nunnelee JS, Stamps JT, Neutzsky-Wulff AV, Barrett RJ, Wang Y, Tang J, Funari VA, Targan SR, Michelsen KS. A role for BATF3 in T9 differentiation and T-cell-driven mucosal pathologies. Mucosal Immunology. PMID 30617301 DOI: 10.1038/S41385-018-0122-4 |
0.667 |
|
| 2019 |
Sandborn WJ, Sands BE, Colombel J, Gasink C, Patel R, Jacobstein D, Gao L, Ghosh S, Targan S, De Villiers W, Hanauer SB, Rutgeerts P, Feagan BG. P034 EFFICACY OF USTEKINUMAB IN CROHN’S DISEASE AT MAINTENENCE WEEK 56: IM-UNITI STUDY Gastroenterology. 156: S23-S24. DOI: 10.1053/J.Gastro.2019.01.086 |
0.317 |
|
| 2019 |
Dube S, Li D, Haritunians T, Yang S, Targan SR, McGovern D. Tu1761 – Polygenic Risk Scores are Associated with Serological Markers Highlighting Disease Heterogeneity in Crohn's Disease (CD) and Ulcerative Colitis (UC) Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39747-1 |
0.413 |
|
| 2019 |
Sands BE, Oortwijn A, Rijnders N, Izanec JL, Gasink C, Jacobstein D, Adedokun OJ, Ma T, Gao L, Colombel JF, Targan SR, Ghosh S, Sandborn WJ. Tu1725 – Characterization of Patients with Delayed Response to Ustekinumab for Crohn's Disease Gastroenterology. 156: S-1100. DOI: 10.1016/S0016-5085(19)39711-2 |
0.368 |
|
| 2019 |
Hanauer SB, Sands BE, Feagan BG, Oortwijn A, van Kruchten R, Laliman VA, Izanec JL, Adedokun OJ, Gao L, Sloan S, Gasink C, Targan SR, de Villiers WJ, Rutgeerts P, Colombel JF, et al. Tu1723 – Identification of Risk Factors Associated with Loss of Response to Ustekinumab in Crohn's Disease Gastroenterology. 156: S-1099. DOI: 10.1016/S0016-5085(19)39709-4 |
0.332 |
|
| 2019 |
Dube S, Li D, Haritunians T, Yang S, Botwin GJ, Targan SR, McGovern D. Su1923 – Novel Associations of Platelets with Clinical and Serologic Variables in Crohn’s Disease (CD) and Ulcerative Colitis (UC) Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)38560-9 |
0.358 |
|
| 2019 |
Potdar AA, Haritunians T, Fiorino MF, Botwin GJ, Li D, Targan SR, McGovern D, Bilsborough J. Su1906 – Markers for Severe, Refractory Crohn’s Disease Derived from Cell Specific Gene Signatures Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)38543-9 |
0.346 |
|
| 2019 |
Shimodaira Y, Abraham J, Hamade H, Blackwood AY, Thomas L, Castanon S, Shih DQ, Targan SR, Michelsen KS. Su1879 – Novel Role for Death Receptor 3 (DR3) Expressed on Intestinal Epithelial Cells in Regulating Homeostatic Intestinal Permeability and Epithelial Cell Proliferation, As Well As Regeneration After Intestinal Mucosal Injury Gastroenterology. 156: S-647. DOI: 10.1016/S0016-5085(19)38516-6 |
0.321 |
|
| 2019 |
Parrish AB, Zaghiyan K, Melmed G, McGovern D, Jain A, Landers C, Targan SR, Fleshner P. Su1856 – A Pilot Study Comparing Postoperative Outcomes After Ustekinumab in Patients with Inflammatory Bowel Disease Gastroenterology. 156: S-636-S-637. DOI: 10.1016/S0016-5085(19)38493-8 |
0.391 |
|
| 2019 |
Torres EA, Rivera AG, Coste-Sibilia S, McGovern D, Targan SR. Sa1849 – Association of Serologic Markers and Surgery in Hispanics with Crohn’s Disease: A Cohort Study of the University of Puerto Rico Inflammatory Bowel Disease Genetic Research Consortium Gastroenterology. 156: S-426-S-427. DOI: 10.1016/S0016-5085(19)37915-6 |
0.382 |
|
| 2019 |
Gleeson JP, Rabizadeh S, Estrada HQ, Li D, McGovern D, Svendsen C, Targan SR, Barrett RJ. Sa1096 – A Personalized Model to Assess Intestinal Permeability in IBD and Veoibd Patients Using Human Ipsc-Derived Intestinal and Colonic Organoids Gastroenterology. 156: S-269-S-270. DOI: 10.1016/S0016-5085(19)37479-7 |
0.783 |
|
| 2019 |
Parrish AB, Zaghiyan K, Lopez N, Melmed G, McGovern D, Jain A, Landers C, Targan SR, Fleshner P. 704 – Preoperative Serum Vedolizumab Levels Do Not Impact Postoperative Outcomes in Inflammatory Bowel Disease Gastroenterology. 156: S-154. DOI: 10.1016/S0016-5085(19)37178-1 |
0.345 |
|
| 2019 |
Gonsky R, Fleshner P, Botwin GJ, Biener-Ramanujan E, McGovern D, Targan SR. 538 – A Blood Based Pre-Surgical Transcriptomic Signature Identifies a Severe Crohn's Disease Subtype and is Predictive of a Post Surgery Decrease in Pro-Inflammatory Pathway Activation Gastroenterology. 156: S-110-S-111. DOI: 10.1016/S0016-5085(19)37068-4 |
0.34 |
|
| 2019 |
Li D, Haritunians T, Mengesha E, Targan SR, McGovern D. 151 – Using Deeplearning and Genetic Bigdata to Predict Crohn's Disease Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)36864-7 |
0.327 |
|
| 2018 |
Castellanos JG, Woo V, Viladomiu M, Putzel G, Lima S, Diehl GE, Marderstein AR, Gandara J, Perez AR, Withers DR, Targan SR, Shih DQ, Scherl EJ, Longman RS. Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis. Immunity. PMID 30552020 DOI: 10.1016/J.Immuni.2018.10.014 |
0.405 |
|
| 2018 |
Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, Devkota S, Braun J, Michelsen KS, Targan SR, Shih DQ. Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. Mucosal Immunology. PMID 29988118 DOI: 10.1038/S41385-018-0055-Y |
0.381 |
|
| 2018 |
Workman MJ, Gleeson JP, Troisi EJ, Estrada HQ, Kerns SJ, Hinojosa CD, Hamilton GA, Targan SR, Svendsen CN, Barrett RJ. Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips. Cellular and Molecular Gastroenterology and Hepatology. 5: 669-677.e2. PMID 29930984 DOI: 10.1016/J.Jcmgh.2017.12.008 |
0.783 |
|
| 2018 |
Lee CK, Melmed GY, Mann A, Danovitch I, Hedrick R, McGovern DPB, Targan S, Shih D, Vasiliauskas E, IsHak WW, Feldman E. A Multidisciplinary Approach to Biopsychosocial Care for Adults With Inflammatory Bowel Disease: A Pilot Study. Inflammatory Bowel Diseases. PMID 29920581 DOI: 10.1093/Ibd/Izy215 |
0.338 |
|
| 2018 |
Li D, Haritunians T, Landers C, Potdar AA, Yang S, Huang H, Schumm LP, Daly M, Targan SR, McGovern DPB. Late-Onset Crohn's Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics. Inflammatory Bowel Diseases. PMID 29860388 DOI: 10.1093/Ibd/Izy148 |
0.364 |
|
| 2018 |
Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, ... ... Targan S, et al. Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. Plos Genetics. 14: e1007329. PMID 29795570 DOI: 10.1371/Journal.Pgen.1007329 |
0.354 |
|
| 2018 |
Rolston VS, Patel AV, Learch TJ, Li D, Karayev D, Williams C, Siddanthi ML, Targan SR, Weisman MH, McGovern DPB. Prevalence and Associations of Avascular Necrosis of the Hip in a Large Well-characterized Cohort of Patients With Inflammatory Bowel Disease. Journal of Clinical Rheumatology : Practical Reports On Rheumatic & Musculoskeletal Diseases. PMID 29794876 DOI: 10.1097/Rhu.0000000000000797 |
0.372 |
|
| 2018 |
Clerc F, Novokmet M, Dotz V, Reiding KR, de Haan N, Kammeijer GSM, Dalebout H, Bladergroen MR, Vukovic F, Rapp E, Targan SR, Barron G, Manetti N, Latiano A, et al. Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases. Gastroenterology. 155: 829-843. PMID 29792883 DOI: 10.1053/J.Gastro.2018.05.030 |
0.386 |
|
| 2018 |
Sands BE, Han C, Gasink C, Jacobstein D, Szapary P, Gao LL, Lang Y, Targan S, Sandborn WJ, Feagan BG. The Effects of Ustekinumab on Health-Related Quality of Life in Patients with Moderate to Severe Crohn's Disease. Journal of Crohn's & Colitis. PMID 29726939 DOI: 10.1093/Ecco-Jcc/Jjy055 |
0.307 |
|
| 2018 |
Šimurina M, de Haan N, Vučković F, Kennedy NA, Štambuk J, Falck D, Trbojević-Akmačić I, Clerc F, Razdorov G, Khon A, Latiano A, D'Incà R, Danese S, Targan S, Landers C, et al. Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases. Gastroenterology. PMID 29309774 DOI: 10.1053/J.Gastro.2018.01.002 |
0.443 |
|
| 2018 |
Lee CK, Li D, Haritunians T, Targan SR, Melmed G, McGovern D. Tu1821 - Multi-Omics Analyses in Crohn's Disease do not Incrementally Predict Poor Outcomes over Endoscopic and Serologic Variables Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)33447-4 |
0.312 |
|
| 2018 |
Akhlaghpour M, Haritunians T, Mengesha E, Li D, Liu Z, McNally R, Landers C, Zaghiyan K, Fleshner P, Melmed G, Targan SR, Silverberg MS, Michelsen KS, McGovern D. Tu1797 - Multi-Center Cohort Analysis Identified a Genetic Association in Complement Factor B with Perianal Crohn's Disease Gastroenterology. 154: S-1022. DOI: 10.1016/S0016-5085(18)33423-1 |
0.343 |
|
| 2018 |
Gonsky R, Fleshner P, Biener-Ramanujan E, McGovern D, Targan SR. Tu1790 - A Sub-Population of Crohn's Disease (CD) Patients with Severe Disease Display Transcriptional Profiling Signatures Enriched for T Cell Trafficking, Mucosal Homing and Inflammatory Response Gastroenterology. 154: S-1020. DOI: 10.1016/S0016-5085(18)33416-4 |
0.439 |
|
| 2018 |
Shimodaira Y, Kanazawa Y, Abraham JP, Kumagai K, Jacob N, Ye Y, Luu J, Michelsen KS, Targan SR, Shih D. Tu1764 - Tl1A Deficiency (But not Dr3-Deficiency) Protects from the Development of Colitis in the Chronic T Cell Transfer Mouse Model by Decreasing Th1 Cell Accumulation in the Intestinal Mucosa Gastroenterology. 154: S-1013. DOI: 10.1016/S0016-5085(18)33390-0 |
0.332 |
|
| 2018 |
Gu P, Dube S, Ko JZ, Li D, Haritunians T, Vasiliauskas E, Syal G, Bonthala N, Yang S, Fleshner P, Melmed G, Targan SR, McGovern D. Sa1809 - Clinical, Serologic, and Genetic Markers are Associated with Complicated Disease Behavior in Patients with Crohn's Disease (CD) Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)31633-0 |
0.406 |
|
| 2017 |
Li H, Song J, Niu G, Zhang H, Guo J, Shih DQ, Targan SR, Zhang X. TL1A blocking ameliorates intestinal fibrosis in the T cell transfer model of chronic colitis in mice. Pathology, Research and Practice. PMID 29254800 DOI: 10.1016/J.Prp.2017.11.017 |
0.397 |
|
| 2017 |
Gu P, Kapur A, Li D, Haritunians T, Vasiliauskas E, Shih DQ, Targan SR, Spiegel BMR, McGovern DPB, Black JT, Melmed GY. Serologic, Genetic, and Clinical Associations with Increased Healthcare Resource Utilization in Inflammatory Bowel Disease. Journal of Digestive Diseases. PMID 29251413 DOI: 10.1111/1751-2980.12566 |
0.392 |
|
| 2017 |
Yoon SM, Haritunians T, Chhina S, Liu Z, Yang S, Landers C, Li D, Ye BD, Shih D, Vasiliauskas EA, Ippoliti A, Rabizadeh S, Targan SR, Melmed GY, McGovern DPB. Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD. Inflammatory Bowel Diseases. PMID 28590340 DOI: 10.1097/Mib.0000000000001150 |
0.381 |
|
| 2017 |
Gonsky R, Fleshner P, Deem RL, Biener-Ramanujan E, Li D, Potdar AA, Bilsborough J, Yang S, McGovern DP, Targan SR. Association of RNASET2 Gene Polymorphisms with Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease. Gastroenterology. PMID 28400196 DOI: 10.1053/J.Gastro.2017.04.002 |
0.44 |
|
| 2017 |
Zhang H, Zheng L, McGovern DP, Hamill AM, Ichikawa R, Kanazawa Y, Luu J, Kumagai K, Cilluffo M, Fukata M, Targan SR, Underhill DM, Zhang X, Shih DQ. Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis. Journal of Immunology (Baltimore, Md. : 1950). PMID 28130498 DOI: 10.4049/Jimmunol.1601293 |
0.391 |
|
| 2017 |
Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB, Shih DQ, Fuhler GM, Parkes M, Kohno K, Iwawaki T, Janneke van der Woude C, Harding HP, ... ... Targan SR, et al. Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis. The Journal of Experimental Medicine. PMID 28082357 DOI: 10.1084/Jem.20160791 |
0.348 |
|
| 2017 |
Syal G, Bonthala N, Feldman EJ, Fleshner P, McGovern DP, Vasiliauskas EA, Melmed GY, Targan SR, Shih DQ. Pharmacokinetic Effect of Anti-tumor Necrosis Factor-alpha Agents on Thiopurine Drug Metabolism in Inflammatory Bowel Diseases American Journal of Gastroenterology. 112: S383-S384. DOI: 10.14309/00000434-201710001-00693 |
0.318 |
|
| 2017 |
Li D, Jacobs J, Braun J, Targan SR, McGovern D. Gut Microbiome Dysbiosis in Crohn's Disease is also Associated with Disease Severity Gastroenterology. 152: S990-S991. DOI: 10.1016/S0016-5085(17)33356-5 |
0.394 |
|
| 2017 |
Potdar AA, Li D, Haritunians T, McGovern D, Targan SR, Bilsborough J. Expression Data From Crohn’s Disease Small Bowel Resections Indicate Distinct Clinical Sub-Groups Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)32165-0 |
0.33 |
|
| 2017 |
Feagan BG, Gasink C, Pollack P, Jacobstein D, Gao L, Johanns J, Miao Y, Targan SR, Ghosh S. Effect of Maintenance Ustekinumab on Corticosteroid-Free Clinical Outcomes in Patients with Crohn’s Disease Gastroenterology. 152: S595. DOI: 10.1016/S0016-5085(17)32131-5 |
0.321 |
|
| 2017 |
Zhu L, Melmed G, Yan X, Haritunians T, Shih DQ, Vasiliauskas E, Ippoliti A, Rabizadeh S, Singh N, Targan SR, Liu Z, Li D, McGovern D. UBE2L3, ANCA, ASCA, and CBIR1 are Associated with Mechanisms of non-Response to Anti-TNF in IBD Patients with Adequate Drug Levels Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)31514-7 |
0.318 |
|
| 2017 |
Gu P, Ko JZ, Yan X, Li D, Haritunians T, Vasiliauskas E, Targan SR, Melmed G, McGovern D, Shih DQ. Serologic and Genetic Markers May Help Predict Disease Behavior in Patients with Crohn'S Disease (CD) Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)31467-1 |
0.387 |
|
| 2017 |
Haritunians T, Li D, Liu Z, Khrom M, Fleshner P, Targan SR, McGovern D. Genetic Associations with Visceral Fat Deposition in Crohn'S Disease Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)31458-0 |
0.341 |
|
| 2017 |
Jacobs J, Tong M, Ruegger P, Li D, Haritunians T, Fleshner P, Vasiliauskas E, Ippoliti A, Melmed G, Shih DQ, Targan SR, Borneman J, McGovern D, Braun J. Crohn's Disease, Obesity, and High Crohn's Disease Genetic Risk are Associated with Parallel Changes in the Microbiome of the Cecal and Sigmoid Mucosal-Luminal Interface Gastroenterology. 152: S111. DOI: 10.1016/S0016-5085(17)30712-6 |
0.351 |
|
| 2017 |
Workman M, Troisi E, Kerns SJ, Hamilton GA, Svendsen C, Targan SR, Barrett RJ. Intestine-Chip: A New Model to Understand the Role of the Intestinal Epithelium in IBD by Combining Microengineering Technology and IPSC-Derived Human Intestinal Organoids Gastroenterology. 152: S57-S58. DOI: 10.1016/S0016-5085(17)30550-4 |
0.726 |
|
| 2016 |
Thomas LS, Targan SR, Tsuda M, Yu QT, Salumbides BC, Haritunians T, Mengesha E, McGovern DP, Michelsen KS. The TNF family member TL1A induces IL-22 secretion in committed human Th17 cells via IL-9 induction. Journal of Leukocyte Biology. PMID 27733581 DOI: 10.1189/Jlb.3A0316-129R |
0.311 |
|
| 2016 |
Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, ... ... Targan SR, et al. Genome-wide Association Study Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease. Gastroenterology. PMID 27693347 DOI: 10.1053/J.Gastro.2016.09.032 |
0.412 |
|
| 2016 |
Jacob N, Targan SR, Shih DQ. Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD. United European Gastroenterology Journal. 4: 531-40. PMID 27536363 DOI: 10.1177/2050640616649356 |
0.414 |
|
| 2016 |
Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess JH, Kugathasan S, Büning C, Schumm LP, Klei L, Ananthakrishnan A, ... ... Targan SR, et al. A pleiotropic missense variant in SLC39A8 is associated with Crohn's disease and human gut microbiome composition. Gastroenterology. PMID 27492617 DOI: 10.1053/J.Gastro.2016.06.051 |
0.431 |
|
| 2016 |
Targan SR, Feagan B, Vermeire S, Panaccione R, Melmed GY, Landers C, Li D, Russell C, Newmark R, Zhang N, Chon Y, Hsu YH, Lin SL, Klekotka P. A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn's Disease. The American Journal of Gastroenterology. PMID 27481309 DOI: 10.1038/Ajg.2016.298 |
0.392 |
|
| 2016 |
Robbins L, Zaghiyan K, Melmed G, Vasiliauskas E, Ahmed S, McGovern D, Rabizadeh S, Singh N, Landers C, Ippoliti A, Shih D, Targan S, Fleshner P. Outcomes with Anti-Tumor Necrosis Factor-Alpha Therapy and Serology in Patients with denovo Crohn's Disease after Ileal Pouch Anal Anastomosis. Journal of Crohn's & Colitis. PMID 27466172 DOI: 10.1093/Ecco-Jcc/Jjw134 |
0.409 |
|
| 2016 |
Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, ... ... Targan S, et al. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF. Gastroenterology. PMID 27377463 DOI: 10.1053/J.Gastro.2016.06.045 |
0.382 |
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| 2016 |
Chu H, Khosravi A, Kusumawardhani IP, Kwon AH, Vasconcelos AC, Cunha LD, Mayer AE, Shen Y, Wu WL, Kambal A, Targan SR, Xavier RJ, Ernst PB, Green DR, McGovern DP, et al. Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease. Science (New York, N.Y.). 352: 1116-20. PMID 27230380 DOI: 10.1126/Science.Aad9948 |
0.419 |
|
| 2016 |
Li D, Silverberg MS, Haritunians T, Dubinsky MC, Landers C, Stempak JM, Milgrom R, Guo X, Chen YI, Rotter JI, Taylor KD, McGovern DP, Targan SR. TNFRSF1B Is Associated with ANCA in IBD. Inflammatory Bowel Diseases. PMID 27104820 DOI: 10.1097/Mib.0000000000000771 |
0.334 |
|
| 2016 |
Koh SZ, Zaghiyan KN, Li Q, Rabizadeh S, Melmed GY, Targan SR, Fleshner PR. Clinical Factors Associated with the Development of Crohn's Disease in Inflammatory Bowel Disease-unclassified Patients Undergoing Ileal Pouch-anal Anastomosis. Inflammatory Bowel Diseases. 22: 1397-402. PMID 26978722 DOI: 10.1097/Mib.0000000000000744 |
0.426 |
|
| 2016 |
Kaur M, Panikkath D, Yan X, Liu Z, Berel D, Li D, Vasiliauskas EA, Ippoliti A, Dubinsky M, Shih DQ, Melmed GY, Haritunians T, Fleshner P, Targan SR, McGovern DP. Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway. Inflammatory Bowel Diseases. PMID 26937622 DOI: 10.1097/Mib.0000000000000705 |
0.387 |
|
| 2016 |
Sandborn W, Gasink C, Blank M, Lang Y, Johanns J, Gao LL, Sands B, Hanauer S, Feagan B, Targan S, Ghosh S, de Villiers W, Colombel JF, Lee S, Desreumaux P, et al. O-001 A Multicenter, Double-Blind, Placebo-Controlled Phase3 Study of Ustekinumab, a Human IL-12/23P40 mAB, in Moderate-Service Crohn's Disease Refractory to Anti-TFNα: UNITI-1. Inflammatory Bowel Diseases. 22: S1. PMID 26849718 DOI: 10.1097/Mib.0000000000000720 |
0.393 |
|
| 2016 |
Sidhu-Varma M, Shih DQ, Targan SR. Differential Levels of Tl1a Affect the Expansion and Function of Regulatory T Cells in Modulating Murine Colitis. Inflammatory Bowel Diseases. 22: 548-59. PMID 26818423 DOI: 10.1097/Mib.0000000000000653 |
0.382 |
|
| 2016 |
Sands B, Gasink C, Jacobstein D, Gao LL, Johanns J, Szapary P, Colombel J, Targan S, Ghosh S, Sandborn WJ. Efficacy and Safety of Dose Adjustment and Delayed Response to Ustekinumab in Moderate - Severe Crohnʼs Disease Patients: Results from the IM-UNITI Maintenance Study: 2016 ACG Presidential Poster Award American Journal of Gastroenterology. 111: S302-S303. DOI: 10.14309/00000434-201610001-00663 |
0.303 |
|
| 2016 |
Nangit A, Scaramangas D, Dejesus G, Karayev D, Williams C, Li D, Yan X, Targan S, Learch T, McGovern D, Weisman M. FRI0406 Prevalence and Significance of Radiographic Sacroiliitis in A Large Inflammatory Bowel Disease Population Annals of the Rheumatic Diseases. 75: 582.2-583. DOI: 10.1136/Annrheumdis-2016-Eular.3313 |
0.338 |
|
| 2016 |
Issokson K, Melmed G, Shih D, Ippoliti A, McGovern D, Targan S, Vasiliauskas E. P-089 A Novel Multi-Disciplinary Approach to Nutrition for Adults with Inflammatory Bowel Disease Inflammatory Bowel Diseases. 22: S37. DOI: 10.1097/01.Mib.0000480194.17762.46 |
0.349 |
|
| 2016 |
Sandborn W, Gasink C, Jacobstein D, Gao L, Johanns J, Targan S, Ghosh S, Hanauer SB. Tu1934 Assessment of Serum C-Reactive Protein, Fecal Lactoferrin, and Fecal Calprotectin in Patients With Moderate-Severely Active Crohns Disease: Results From the IM UNITI Maintenance Study Gastroenterology. 150: S982. DOI: 10.1016/S0016-5085(16)33327-3 |
0.335 |
|
| 2016 |
Jacob N, Kumagai K, Kanazawa Y, Hamill AM, Flores E, Kim Y, Sartor RB, Targan S, Jacobs J, Shih DQ. Su1870 Differing Microbial Populations Induce TL1A-Mediated Intestinal Fibrosis Independently of TL1A-Mediated Inflammation Gastroenterology. 150: S575. DOI: 10.1016/S0016-5085(16)31969-2 |
0.314 |
|
| 2016 |
Gonsky R, Deem R, Biener-Ramanujan E, yang S, McGovern D, Targan S. Su1856 RNASET2: A CD Severity Biomarker Related to TL1A Driven Inflammation Gastroenterology. 150: S571. DOI: 10.1016/S0016-5085(16)31955-2 |
0.309 |
|
| 2016 |
Li D, Huang H, Haritunians T, Rabizadeh S, Daly MJ, Targan S, McGovern D. Su1855 Genetic Burden Analysis Identified Late-Onset Crohn's Disease(CD) As a Distinct Subgroup Characterized by Low Genetic Burden, UC-Like Serological Markers, Mild Clinical Phenotypes and High Proportion of Smoking Cessation at Diagnosis Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)31954-0 |
0.333 |
|
| 2016 |
Rezaie A, Pimentel M, Chang BW, Pan D, Chua KS, Lentz G, Sonesen M, Estiandan R, Vasiliauskas E, Targan S, Yan X, Li D, McGovern D. Su1793 Breath Methane and Hydrogen Composition in Inflammatory Bowel Disease (IBD) Is Strikingly Different From Non-IBD Patients and Is Associated With IBD-Associated Genes: A Large-Scale Database Linkage Analysis Gastroenterology. 150: S553. DOI: 10.1016/S0016-5085(16)31892-3 |
0.388 |
|
| 2016 |
Sandborn W, Feagan BG, Gasink C, Jacobstein D, Gao L, Johanns J, Sands BE, Hanauer SB, Targan S, Ghosh S, Villiers WJd, Colombel J, Lee S, Dieleman LA, Katz S, et al. 768 A Phase 3 Randomized, Multicenter, Double-Blind, Placebo-Controlled Study of Ustekinumab Maintenance Therapy in Moderate - Severe Crohn's Disease Patients: Results From IM-UNITI Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30623-0 |
0.327 |
|
| 2016 |
Yoon SM, Haritunians T, Chhina S, Ye BD, Shih DQ, Vasiliauskas E, Ippoliti A, Targan S, Melmed GY, McGovern D. 188 Factors Predicting Response to Anti-TNF Agents for Patients With Inflammatory Bowel Disease Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30289-X |
0.383 |
|
| 2015 |
Ahmed S, Melmed G, McGovern D, Robbins LA, Shih D, Vasiliauskas E, Singh N, Rabidzadeh S, Ippoliti A, Targan S, Fleshner P. Nonbloody Diarrhea but Not Significant Weight Loss at Diagnosis Is Associated with the Development of Denovo Crohn's Disease After Ileal Pouch-anal Anastomosis for Ulcerative Colitis. Inflammatory Bowel Diseases. PMID 26595552 DOI: 10.1097/Mib.0000000000000630 |
0.374 |
|
| 2015 |
Taleban S, Li D, Targan SR, Ippoliti A, Brant SR, Cho JH, Duerr RH, Rioux JD, Silverberg MS, Vasiliauskas EA, Rotter JI, Haritunians T, Shih DQ, Dubinsky M, Melmed GY, et al. Ocular Manifestations in Inflammatory Bowel Disease are Associated with Other Extra-Intestinal Manifestations, Gender, and Genes Implicated in Other Immune-Related Traits. Journal of Crohn's & Colitis. PMID 26449790 DOI: 10.1093/Ecco-Jcc/Jjv178 |
0.422 |
|
| 2015 |
Taleban S, Van Oijen MG, Vasiliauskas EA, Fleshner PR, Shen B, Ippoliti AF, Targan SR, Melmed GY. Colectomy with Permanent End Ileostomy Is More Cost-Effective than Ileal Pouch-Anal Anastomosis for Crohn's Colitis. Digestive Diseases and Sciences. PMID 26434930 DOI: 10.1007/S10620-015-3886-3 |
0.372 |
|
| 2015 |
Huang C, Haritunians T, Okou DT, Cutler DJ, Zwick ME, Taylor KD, Datta LW, Maranville JC, Liu Z, Ellis S, Chopra P, Alexander JS, Baldassano RN, Cross RK, Dassopoulos T, ... ... Targan SR, et al. Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans. Gastroenterology. PMID 26278503 DOI: 10.1053/J.Gastro.2015.07.065 |
0.351 |
|
| 2015 |
Weizman AV, Huang B, Targan S, Dubinsky M, Fleshner P, Kaur M, Ippoliti A, Panikkath D, Vasiliauskas E, Shih D, McGovern DP, Melmed GY. Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study. Journal of Cutaneous Medicine and Surgery. 19: 125-31. PMID 25775631 DOI: 10.2310/7750.2014.14053 |
0.433 |
|
| 2015 |
Hyun J, Romero L, Riveron R, Flores C, Kanagavelu S, Chung KD, Alonso A, Sotolongo J, Ruiz J, Manukyan A, Chun S, Singh G, Salas P, Targan SR, Fukata M. Human intestinal epithelial cells express interleukin-10 through Toll-like receptor 4-mediated epithelial-macrophage crosstalk. Journal of Innate Immunity. 7: 87-101. PMID 25171731 DOI: 10.1159/000365417 |
0.303 |
|
| 2015 |
Lau C, Dubinsky M, Melmed G, Vasiliauskas E, Berel D, McGovern D, Ippoliti A, Shih D, Targan S, Fleshner P. The impact of preoperative serum anti-TNFα therapy levels on early postoperative outcomes in inflammatory bowel disease surgery. Annals of Surgery. 261: 487-96. PMID 24950263 DOI: 10.1097/Sla.0000000000000757 |
0.366 |
|
| 2015 |
Robbins L, Yan X, Chhina S, Dailey F, Pan D, Haritunians T, Shih D, Ippoliti A, Vasiliauskas E, Melmed G, Targan S, McGovern D. Psoriasis in Inflammatory Bowel Disease (IBD) Patients Is Associated With Erythema Nodosum and IBD-Associated Genes, But Is Less Prevalent in Patients Taking Anti-TNF Therapies Presidential Poster: 1981 The American Journal of Gastroenterology. 110. DOI: 10.14309/00000434-201510001-01981 |
0.409 |
|
| 2015 |
Pourmorady J, Nguyen M, McPhaul C, Morganstern B, Deepti D, Fleshner P, Vasiliauskas E, Melmed G, Ippoliti A, Targan S, McGovern D, Shih D. Inflammatory Bowel Disease Patients With High-Grade Cytomegalovirus Infection May Benefit From Antiviral Therapy American Journal of Gastroenterology. 110: S827. DOI: 10.14309/00000434-201510001-01951 |
0.362 |
|
| 2015 |
Melmed G, Mann A, Feldman E, Danovitch I, Hedrick R, McGovern D, Targan S, Shih D, Ippoliti A, Vasiliauskas E, Ishak W. A Novel Multi-Disciplinary Approach to BioPsychoSocial Care for Adults with Inflammatory Bowel Disease American Journal of Gastroenterology. 110: S824. DOI: 10.14309/00000434-201510001-01943 |
0.327 |
|
| 2015 |
Huang BL, Vu M, Kaushal N, Zaghiyan K, Rutgers J, Ippoliti A, Targan S, Rezaie A. Ileal DALM in Crohnʼs Disease: An Overlooked Entity? American Journal of Gastroenterology. 110: S292. DOI: 10.14309/00000434-201510001-00660 |
0.358 |
|
| 2015 |
Nguyen M, Pourmorady JS, Morganstern B, Yan X, Zhang A, Karsan SS, Fleshner P, Vasiliauskas EA, Melmed G, Ippoliti A, Targan S, McGovern D, Shih D. Mo1750 Genetic Associations With Preferential 6TGN Metabolizers Reveal Novel Pathways Involved in Purine Metabolism Gastroenterology. 148: S-702. DOI: 10.1016/S0016-5085(15)32380-5 |
0.4 |
|
| 2015 |
Morganstern B, Singh N, Targan S, Landers CJ, Nguyen M, Vasiliauskas EA, Shih D, Feldman EJ, Ippoliti A, McGovern D, Dubinsky M, Rabizadeh S, Melmed GY. Sa1182 Single-Center Experience of Vedolizumab in Patients With Inflammatory Bowel Disease: Does Age Matter? Gastroenterology. 148: S-250. DOI: 10.1016/S0016-5085(15)30822-2 |
0.399 |
|
| 2015 |
Robbins L, Zaghiyan KN, Melmed GY, Vasiliauskas EA, McGovern D, Ippoliti A, Shih DQ, Targan S, Fleshner P. Sa1152 Do Anti-TNF Agents Work in Ulcerative Colitis Patients With de novo Crohn's Disease Who Failed Anti-TNF Therapy Before Ileal Pouch-Anal Anastomosis? Gastroenterology. 148: S-241. DOI: 10.1016/S0016-5085(15)30792-7 |
0.382 |
|
| 2015 |
Li D, Haritunians T, Landers CJ, Yan X, Targan S, McGovern D, Rich SS. 388 Identifying Genetically Homogeneous Crohn's Disease Subgroups Through Serological Profiling Gastroenterology. 148: S-80-S-81. DOI: 10.1016/S0016-5085(15)30282-1 |
0.357 |
|
| 2014 |
Halloran B, Chang J, Shih DQ, McGovern D, Famulski K, Evaschesen C, Fedorak RN, Thiesen A, Targan S, Halloran PF. Molecular patterns in human ulcerative colitis and correlation with response to infliximab. Inflammatory Bowel Diseases. 20: 2353-63. PMID 25397893 DOI: 10.1097/Mib.0000000000000239 |
0.385 |
|
| 2014 |
Barrett R, Ornelas L, Yeager N, Mandefro B, Sahabian A, Lenaeus L, Targan SR, Svendsen CN, Sareen D. Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines. Stem Cells Translational Medicine. 3: 1429-34. PMID 25298370 DOI: 10.5966/Sctm.2014-0121 |
0.739 |
|
| 2014 |
Weizman AV, Huang B, Targan S, Dubinsky M, Fleshner P, Kaur M, Ippoliti A, Panikkath D, Vasiliauskas E, Shih D, McGovern DP, Melmed GY. Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study. Journal of Cutaneous Medicine and Surgery. 18: 361. PMID 25277124 |
0.317 |
|
| 2014 |
Khanna PV, Shih DQ, Haritunians T, McGovern DP, Targan S. Use of animal models in elucidating disease pathogenesis in IBD. Seminars in Immunopathology. 36: 541-51. PMID 25212688 DOI: 10.1007/S00281-014-0444-6 |
0.435 |
|
| 2014 |
Gonsky R, Deem RL, Landers CJ, Haritunians T, Yang S, Targan SR. IFNG rs1861494 polymorphism is associated with IBD disease severity and functional changes in both IFNG methylation and protein secretion. Inflammatory Bowel Diseases. 20: 1794-801. PMID 25171510 DOI: 10.1097/Mib.0000000000000172 |
0.385 |
|
| 2014 |
Alexander KL, Targan SR, Elson CO. Microbiota activation and regulation of innate and adaptive immunity. Immunological Reviews. 260: 206-20. PMID 24942691 DOI: 10.1111/Imr.12180 |
0.431 |
|
| 2014 |
Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. Journal of Immunology (Baltimore, Md. : 1950). 193: 940-9. PMID 24935928 DOI: 10.4049/Jimmunol.1400093 |
0.384 |
|
| 2014 |
Horton HA, Dezfoli S, Berel D, Hirsch J, Ippoliti A, McGovern D, Kaur M, Shih D, Dubinsky M, Targan SR, Fleshner P, Vasiliauskas EA, Grein J, Murthy R, Melmed GY. Antibiotics for Treatment of Clostridium difficile Infection in Hospitalized Patients with Inflammatory Bowel Disease. Antimicrobial Agents and Chemotherapy. 58: 5054-9. PMID 24913174 DOI: 10.1128/Aac.02606-13 |
0.378 |
|
| 2014 |
Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal Immunology. 7: 1492-503. PMID 24850426 DOI: 10.1038/Mi.2014.37 |
0.349 |
|
| 2014 |
Weizman A, Huang B, Berel D, Targan SR, Dubinsky M, Fleshner P, Ippoliti A, Kaur M, Panikkath D, Brant S, Oikonomou I, Duerr R, Rioux J, Silverberg M, Rotter JI, et al. Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients. Inflammatory Bowel Diseases. 20: 525-33. PMID 24487271 DOI: 10.1097/01.Mib.0000442011.60285.68 |
0.434 |
|
| 2014 |
Vu MP, Melmed GY, Targan SR. Weeding out the facts: The reality about cannabis and crohn's disease Clinical Gastroenterology and Hepatology. 12: 898-899. PMID 24269921 DOI: 10.1016/J.Cgh.2013.11.016 |
0.365 |
|
| 2014 |
VanDussen KL, Liu TC, Li D, Towfic F, Modiano N, Winter R, Haritunians T, Taylor KD, Dhall D, Targan SR, Xavier RJ, McGovern DP, Stappenbeck TS. Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease. Gastroenterology. 146: 200-9. PMID 24076061 DOI: 10.1053/J.Gastro.2013.09.048 |
0.385 |
|
| 2014 |
Chhina S, Steadman K, Goel G, Nguyen K, Targan S, Li X, Haritunians T, Li D, Yang S, McGovern D. Small Bowel Location, Stricturing Behavior, Vitamin D Receptor Polymorphism, and Metabolic Disease Susceptibility Genes Are Associated With NAFLD in Crohn’s Disease: 1704 The American Journal of Gastroenterology. 109. DOI: 10.14309/00000434-201410002-01704 |
0.324 |
|
| 2014 |
Gonsky R, Deem R, Kakuta Y, McGovern DP, Targan S. Tu1926 Functional Characterization of the CD40 IBD Risk SNP rs6074022: Integrated Gwas, eQTL, and mQTL Defines IBD Patient Subgroups With Altered Pathobiology and Distinct Natural History of Disease Gastroenterology. 146: S-874. DOI: 10.1016/S0016-5085(14)63180-2 |
0.404 |
|
| 2014 |
Goel G, Tong M, Li X, Baron G, Targan S, McGovern DP, Braun J. Tu1764 Relationship of Microbial Serology and Luminal Microbiome Composition in Crohn's Disease Gastroenterology. 146: S-837. DOI: 10.1016/S0016-5085(14)63040-7 |
0.351 |
|
| 2014 |
Fu N, Yan X, Haritunians T, Targan S, Melmed GY, Vasiliauskas EA, McGovern DP. Mo1242 Genetic, Serological and Clinical Associations in Inflammatory Bowel Disease (IBD) Patients With Clostridium difficile Infection (CDI) Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)62157-0 |
0.396 |
|
| 2014 |
Barrett R, Yeager N, Rushton D, Ornelas L, Sareen D, Svendsen C, Targan S. Su1989 Generation of Functional Human Intestinal Organoids From Lymphoblastoid B-Cell Lines: Opportunity for Gene Specific Functional Assessment in IBD Gastroenterology. 146: S-516. DOI: 10.1016/S0016-5085(14)61868-0 |
0.721 |
|
| 2014 |
Zaghiyan KN, Melmed GY, Dubinsky M, Vasiliauskas EA, McGovern DP, Ippoliti A, Shih DQ, Khanna P, Targan S, Fleshner P. Su1384 Medical Prophylaxis After Ileocolic Resection for Crohn's Disease – No Need to Rush Gastroenterology. 146: S-454. DOI: 10.1016/S0016-5085(14)61627-9 |
0.321 |
|
| 2014 |
Ho S, Cheng M, Shih DQ, Vu M, Hing T, Kubota Y, Ichikawa R, Tran DH, Gallo R, Targan S, Pothoulakis C, Koon HW. Su1288 Intestinal Cathelicidin Level Indicates Inflammatory Bowel Disease Activity and Mediates Anti-Inflammatory Effects in Colitis Gastroenterology. 146: S-426. DOI: 10.1016/S0016-5085(14)61534-1 |
0.405 |
|
| 2013 |
Wallis D, Asaduzzaman A, Weisman M, Haroon N, Anton A, McGovern D, Targan S, Inman R. Elevated serum anti-flagellin antibodies implicate subclinical bowel inflammation in ankylosing spondylitis: an observational study. Arthritis Research & Therapy. 15: R166. PMID 24286190 DOI: 10.1186/Ar4350 |
0.358 |
|
| 2013 |
Dubinsky MC, Kugathasan S, Kwon S, Haritunians T, Wrobel I, Wahbeh G, Quiros A, Bahar R, Silber G, Farrior S, Stephens M, Teleten N, Panikkath D, Ippoliti A, Vasiliauskas E, ... ... Targan SR, et al. Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease. Inflammatory Bowel Diseases. 19: 1662-70. PMID 23665963 DOI: 10.1097/Mib.0B013E318281F275 |
0.31 |
|
| 2013 |
Gonsky R, Deem RL, Targan SR. Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells. Cytokine. 63: 36-42. PMID 23642711 DOI: 10.1016/J.Cyto.2013.04.004 |
0.322 |
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| 2013 |
Zheng L, Zhang X, Chen J, Ichikawa R, Wallace K, Pothoulakis C, Koon HW, Targan SR, Shih DQ. SUSTAINED TL1A (TNFSF15) EXPRESSION ON BOTH LYMPHOID AND MYELOID CELLS LEADS TO MILD SPONTANEOUS INTESTINAL INFLAMMATION AND FIBROSIS. European Journal of Microbiology & Immunology. 3: 11-20. PMID 23638306 DOI: 10.1556/Eujmi.3.2013.1.2 |
0.364 |
|
| 2013 |
Koon HW, Shih DQ, Hing TC, Yoo JH, Ho S, Chen X, Kelly CP, Targan SR, Pothoulakis C. Human monoclonal antibodies against Clostridium difficile toxins A and B inhibit inflammatory and histologic responses to the toxins in human colon and peripheral blood monocytes. Antimicrobial Agents and Chemotherapy. 57: 3214-23. PMID 23629713 DOI: 10.1128/Aac.02633-12 |
0.312 |
|
| 2013 |
Michelsen KS, Wong MH, Ko B, Thomas LS, Dhall D, Targan SR. HMPL-004 (Andrographis paniculata extract) prevents development of murine colitis by inhibiting T-cell proliferation and TH1/TH17 responses Inflammatory Bowel Diseases. 19: 151-164. PMID 23292349 DOI: 10.1002/Ibd.22983 |
0.396 |
|
| 2013 |
Surti B, Spiegel B, Ippoliti A, Vasiliauskas EA, Simpson P, Shih DQ, Targan SR, McGovern DP, Melmed GY. Assessing health status in inflammatory bowel disease using a novel single-item numeric rating scale. Digestive Diseases and Sciences. 58: 1313-21. PMID 23250673 DOI: 10.1007/S10620-012-2500-1 |
0.357 |
|
| 2013 |
Le Q, Melmed G, Dubinsky M, McGovern D, Vasiliauskas EA, Murrell Z, Ippoliti A, Shih D, Kaur M, Targan S, Fleshner P. Surgical outcome of ileal pouch-anal anastomosis when used intentionally for well-defined Crohn's disease. Inflammatory Bowel Diseases. 19: 30-6. PMID 22467562 DOI: 10.1002/Ibd.22955 |
0.381 |
|
| 2013 |
Wallis D, Weisman M, Haroon N, Anton A, Govern DM, Targan S, Inman R. OP0241 Anti-Flagellin Antibodies in Ankylosing Spondylitis (AS) Implicate Subclinical Bowel Inflammation and Differentiate as from Mechanical Back Pain Patients Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-Eular.446 |
0.385 |
|
| 2013 |
Haritunians T, Li D, Liu Z, Yan X, Eric V, Ippoliti A, Dubinsky M, Shih D, Melmed G, Fleshner P, Targan S, McGovern D. P-218 Exome Chip Analysis of Perianal Crohn’s Disease Identifies Novel Loci Not Previously Described using Immunochip Platform Inflammatory Bowel Diseases. 19. DOI: 10.1097/01.Mib.0000439016.44908.3D |
0.315 |
|
| 2013 |
Liu T, VanDussen K, Gao F, Li D, Towfic F, Modiano N, Winter R, Haritunians T, Dhall D, Targan S, Xavier R, McGovern D, Stappenbeck T. O-025 Paneth Cell Phenotype Correlates with Genetics, Transcriptome Profile, Pathologic Hallmark and Predicts Clinical Outcome in Patients with Crohnʼs Disease Inflammatory Bowel Diseases. 19: S15. DOI: 10.1097/01.Mib.0000438994.14825.01 |
0.319 |
|
| 2013 |
Zaghiyan K, Barmparas G, Dubinsky M, Melmed G, Eric V, McGovern D, Ippoliti A, Shih D, Targan S, Fleshner P. P-160 YI Preoperative Anti-TNFα Therapy Is Associated with Increased Incidence and Shorter Interval to De Novo Crohnʼs Disease After Ileal-Pouch Anal Anastomosis Inflammatory Bowel Diseases. 19: S90. DOI: 10.1097/01.Mib.0000438902.94123.69 |
0.347 |
|
| 2013 |
Taleban S, Li D, Targan S, Ippoliti A, Vasiliauskas EA, Rotter JI, Shih DQ, Kaur M, Dubinsky M, Melmed GY, McGovern DP. Mo1304 Clinical, Serologic, and Genetic Associations in Patients With Ocular Manifestations in Inflammatory Bowel Disease Gastroenterology. 144: S-631. DOI: 10.1016/S0016-5085(13)62337-9 |
0.41 |
|
| 2013 |
Gerich ME, Fleshner P, Panikkath D, Winter R, Yoon JL, Ocampo LH, Al-Jiboury H, Kwon S, Haritunians T, Berel D, Dubinsky M, Targan SR, Melmed GY, McGovern DP. Mo1299 Genotype and Post-Operative Immunosuppression Impact Surgical Recurrence in Crohn's Disease Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)62332-X |
0.318 |
|
| 2013 |
Kakuta Y, Dubinsky M, Li D, Song K, Yang S, Ye BD, Rich SS, Onengut-Gumuscu S, Torres EA, Panikkath D, Haritunians T, Targan SR, Rotter JI, Taylor KD, McGovern DP. Su1750 Transethnic Fine-Mapping of the IL12B Locus Identifies Two Independent Signals Associated With IBD Susceptibility and Disease Behaviors Gastroenterology. 144: S-467. DOI: 10.1016/S0016-5085(13)61727-8 |
0.306 |
|
| 2013 |
Gonsky R, Deem R, McGovern DP, Targan SR. Su1747 Combined Epigenetic and mRNA Expression Profiling Defines a Crohn's Disease (CD) Patient Population With Need for Early Surgical Intervention Gastroenterology. 144: S-466. DOI: 10.1016/S0016-5085(13)61724-2 |
0.309 |
|
| 2013 |
Kakuta Y, Song K, Yang S, Ye BD, Torres EA, Rich SS, Onengut-Gumuscu S, Dubinsky M, Taylor KD, Rotter JI, Haritunians T, Targan SR, Li D, McGovern DP. Su1746 Rare Variants of TNFSF15 Are Significantly Associated With Crohn's Disease in Non-Jewish Caucasian Independent of the Known Common Susceptibility SNPs Gastroenterology. 144: S-466. DOI: 10.1016/S0016-5085(13)61723-0 |
0.306 |
|
| 2013 |
Lau CC, Dubinsky M, Melmed GY, Vasiliauskas EA, McGovern DP, Berel D, Murrell ZA, Ippoliti A, Shih DQ, Kaur M, Targan SR, Fleshner P. Su1133 Influence of Biologic Agents on Short-Term Postoperative Complications in Patients With Crohn's Disease: A Prospective, Single-Surgeon Cohort Study Gastroenterology. 144: S-407. DOI: 10.1016/S0016-5085(13)61500-0 |
0.343 |
|
| 2013 |
Lin L, Ma C, Wei B, Rajalingam R, Yusung S, Trachtenberg EA, Targan SR, McGovern DP, Braun J. Sa1778 Genetically-Determined Cytokine Programs of Human Natural Killer (NK) Cells Uncover a Novel Mechanism of NK Cells and Kir Genes in Crohn's Disease Susceptibility Gastroenterology. 144: S-304. DOI: 10.1016/S0016-5085(13)61089-6 |
0.425 |
|
| 2013 |
Kaur M, Panikkath D, Li D, Berel D, Vasiliauskas EA, Ippoliti A, Dubinsky M, Shih DQ, Melmed GY, Taylor KD, Fleshner P, Targan SR, McGovern DP. 562 Perianal Crohn's Disease Is Associated With Distal Colonic Disease, IBD-Related Serologies and Immune-Related Genetic Variation Gastroenterology. 144: S-104. DOI: 10.1016/S0016-5085(13)60382-0 |
0.395 |
|
| 2013 |
Hing T, Koon HW, Shih DQ, Hwan Yoo J, Ho S, Chen X, Kelly CP, Targan SR, Pothoulakis C. 136 Human Monoclonal Antibodies Against Clostridium difficile Toxin a and B Inhibit Inflammatory Responses and Epithelial Cell Damage to Toxins a and B in Human Peripheral Blood Monocytes and Human Colonic Tissues Gastroenterology. 144: S-32-S-33. DOI: 10.1016/S0016-5085(13)60116-X |
0.306 |
|
| 2012 |
Matzkies FG, Targan SR, Berel D, Landers CJ, Reveille JD, McGovern DP, Weisman MH. Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study. Arthritis Research & Therapy. 14: R261. PMID 23194008 DOI: 10.1186/Ar4106 |
0.385 |
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| 2012 |
Salehi S, Bankoti R, Benevides L, Willen J, Couse M, Silva JS, Dhall D, Meffre E, Targan S, Martins GA. B lymphocyte-induced maturation protein-1 contributes to intestinal mucosa homeostasis by limiting the number of IL-17-producing CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 5682-93. PMID 23162130 DOI: 10.4049/Jimmunol.1201966 |
0.343 |
|
| 2012 |
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, ... ... Targan SR, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 491: 119-24. PMID 23128233 DOI: 10.1038/Nature11582 |
0.433 |
|
| 2012 |
Sandborn WJ, Gasink C, Gao LL, Blank MA, Johanns J, Guzzo C, Sands BE, Hanauer SB, Targan S, Rutgeerts P, Ghosh S, de Villiers WJ, Panaccione R, Greenberg G, Schreiber S, et al. Ustekinumab induction and maintenance therapy in refractory Crohn's disease. The New England Journal of Medicine. 367: 1519-28. PMID 23075178 DOI: 10.1056/Nejmoa1203572 |
0.323 |
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| 2012 |
White EC, Melmed GY, Vasiliauskas E, Dubinsky M, Ippoliti A, McGovern D, Targan S, Fleshner P. Does preoperative immunosuppression influence unplanned hospital readmission after surgery in patients with Crohn's disease? Diseases of the Colon and Rectum. 55: 563-8. PMID 22513435 DOI: 10.1097/Dcr.0B013E3182468961 |
0.336 |
|
| 2012 |
Sandborn WJ, Colombel JF, Sands BE, Rutgeerts P, Targan SR, Panaccione R, Bressler B, Geboes K, Schreiber S, Aranda R, Gujrathi S, Luo A, Peng Y, Salter-Cid L, Hanauer SB. Abatacept for Crohn's disease and ulcerative colitis. Gastroenterology. 143: 62-69.e4. PMID 22504093 DOI: 10.1053/J.Gastro.2012.04.010 |
0.336 |
|
| 2012 |
Basseri RJ, Basseri B, Vassilaki ME, Melmed GY, Ippoliti A, Vasiliauskas EA, Fleshner PR, Lechago J, Hu B, Berel D, Targan SR, Papadakis KA. Colorectal cancer screening and surveillance in Crohn's colitis. Journal of Crohn's & Colitis. 6: 824-9. PMID 22398087 DOI: 10.1016/J.Crohns.2012.01.005 |
0.331 |
|
| 2012 |
Murdoch TB, Xu W, Stempak JM, Landers C, Targan SR, Rotter JI, Silverberg MS. Pattern recognition receptor and autophagy gene variants are associated with development of antimicrobial antibodies in Crohn's disease. Inflammatory Bowel Diseases. 18: 1743-8. PMID 22275320 DOI: 10.1002/Ibd.22884 |
0.398 |
|
| 2012 |
Vora P, Shih DQ, McGovern DP, Targan SR. Current concepts on the immunopathogenesis of inflammatory bowel disease. Frontiers in Bioscience (Elite Edition). 4: 1451-77. PMID 22201968 |
0.312 |
|
| 2012 |
Barrett R, Zhang X, Koon HW, Vu M, Chang JY, Yeager N, Nguyen MA, Michelsen KS, Berel D, Pothoulakis C, Targan SR, Shih DQ. Constitutive TL1A expression under colitogenic conditions modulates the severity and location of gut mucosal inflammation and induces fibrostenosis. The American Journal of Pathology. 180: 636-49. PMID 22138299 DOI: 10.1016/J.Ajpath.2011.10.026 |
0.709 |
|
| 2012 |
Yoon J, Gerich M, Targan S, Ippoliti A, Vasiliauskas E. Long-Term Outcomes of Thalidomide in Refractory Inflammatory Bowel Disease American Journal of Gastroenterology. 107: S694-S695. DOI: 10.14309/00000434-201210001-01713 |
0.342 |
|
| 2012 |
Ma C, Lin L, Erlich H, Trachtenberg E, Targan S, McGovern D, Heath J, Ribas A, Braun J. KIR Genetics Modifies Susceptibility to Inflammatory Disorder by Reprogramming Human Natural Killer Cell Function Blood. 120: 3282-3282. DOI: 10.1182/Blood.V120.21.3282.3282 |
0.377 |
|
| 2012 |
Lin L, Ma C, Wei B, McHardy I, Targan SR, McGovern DP, Braun J. Tu1948 KIR2DL3- and 3DL1-Mediated NK Cell Education Confers Crohn's Disease Susceptibility Gastroenterology. 142: S-884. DOI: 10.1016/S0016-5085(12)63435-0 |
0.34 |
|
| 2012 |
Koon HW, Chen J, Ichikawa R, Shih DQ, Ho S, Cheng M, Hing T, Vu M, Law I, Zhao D, Gallo R, Targan SR, Pothoulakis C. Tu1919 Anti-Inflammatory Effects of Anti-Microbial Peptide Cathelicidin in Mice With Acute Colitis Gastroenterology. 142: S-878. DOI: 10.1016/S0016-5085(12)63406-4 |
0.332 |
|
| 2012 |
Vu M, Li D, Dubinsky M, Taylor KD, Haritunians T, Dutridge D, Rotter JI, Targan SR, McGovern DP. Tu1907 Gene-Smoking Interactions in Inflammatory Bowel Disease Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)63394-0 |
0.338 |
|
| 2012 |
Gonsky R, Deem R, Targan SR. Tu1859 Transactivation of the Crohn's Disease Severity Gene, TL1A, Requires the Interplay Between Multiple Activating and Repressive CIS-Regulatory Regions Gastroenterology. 142: S-862. DOI: 10.1016/S0016-5085(12)63346-0 |
0.318 |
|
| 2012 |
Williams CI, Karayev D, Learch T, Targan SR, Landers CJ, Rotter JI, Vasiliauskas EA, Ippoliti A, Kaur M, Melmed GY, Shih DQ, Dubinsky M, Taylor KD, Li D, Weisman MH, et al. Mo1695 Clinical, Serologic, and Genetic Associations Among Patients With Both Inflammatory Bowel Disease and Ankylosing Spondylitis Gastroenterology. 142: S-662. DOI: 10.1016/S0016-5085(12)62550-5 |
0.364 |
|
| 2012 |
Dezfoli S, Horton HA, Berel D, Targan SR, Vasiliauskas EA, Dubinsky M, Kaur M, McGovern DP, Ippoliti A, Feldman EJ, Melmed G. Su2081 Immunomodulators, but Not Anti-TNF Monotherapy, Impair Pertussis and Tetanus Booster Vaccine Responses in Adults With Inflammatory Bowel Disease (IBD) Gastroenterology. 142: S-564-S-565. DOI: 10.1016/S0016-5085(12)62169-6 |
0.349 |
|
| 2012 |
Karsan SS, Cohen ER, Targan SR, Ippoliti A, Shih DQ, Vasiliauskas EA, Dubinsky M, Berel D, McGovern DP. Sa1289 Analysis of Clinical and Serological Associations, and the Clinical Consequences of the Development of Human Anti-Chimeric Antibodies (HACAs), and Low Serum Infliximab (IFX) Levels in Inflammatory Bowel Disease (IBD) Gastroenterology. 142: S-264. DOI: 10.1016/S0016-5085(12)60996-2 |
0.38 |
|
| 2012 |
Hing T, Ho S, Shih DQ, Ichikawa R, Chen J, Cheng M, Chen X, Law I, Hansen J, Najarian RM, Kelly CP, Feng H, Gallo R, Targan SR, Pothoulakis C, et al. 1107 The Anti-Microbial Peptide Cathelicidin Modulates Clostridium difficile Toxin a - Mediated Inflammatory Responses in Mouse Intestine and Human Primary Monocytes Gastroenterology. 142: S-200. DOI: 10.1016/S0016-5085(12)60750-1 |
0.338 |
|
| 2012 |
Zaghiyan KN, Berel D, McGovern DP, Dubinsky M, Vasiliauskas EA, Melmed GY, Ippoliti A, Kaur M, Shih DQ, Murrell ZA, Targan SR, Fleshner P. 1070 Validated Nomogram for Preoperative Prediction of Chronic Pouchitis and Denovo Crohn's Disease After Ileal Pouch-Anal Anastomosis Gastroenterology. 142: S-190. DOI: 10.1016/S0016-5085(12)60713-6 |
0.331 |
|
| 2012 |
Shih DQ, Zhang X, Koon HW, Chang J, Chen J, Huang BL, Li C, Zheng L, Pothoulakis C, Targan SR. 357 Reversal of Murine Colitis and Fibrosis by Neutralizing TL1A Antibody: Potential Novel Therapy to Alter Natural History of Crohn's Disease Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60318-7 |
0.366 |
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| 2012 |
Essers JB, Ripke S, Neale B, Xavier RJ, Vu M, Dubinsky M, Rotter JI, Targan SR, McGovern DP, Daly MJ. 162 Genetics, Serologies, and Smoking Predict Highly Morbid Crohn's Disease in Erroneously Diagnosed UC Patients Gastroenterology. 142: S-39-S-40. DOI: 10.1016/S0016-5085(12)60151-6 |
0.319 |
|
| 2012 |
Huang BL, Weizman AV, Berel D, Shih DQ, Targan SR, Dubinsky M, Li D, Kaur M, Haritunians T, Taylor KD, Melmed GY, McGovern DP. 29 Inflammatory Bowel Disease and Erythema Nodosum: Clinical, Serologic, and Genetic Associations Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60029-8 |
0.397 |
|
| 2012 |
Weizman AV, Huang BL, Berel D, Targan SR, Dubinsky M, Fleshner P, Ippoliti A, Rotter JI, Vasiliauskas EA, Shih DQ, Li D, Melmed GY, McGovern DP. 26 Serologic and Genetic Profiles Suggest Distinct Immune Pathways Among Patients With Pyoderma Gangrenosum and Inflammatory Bowel Disease Gastroenterology. 142: S-7. DOI: 10.1016/S0016-5085(12)60026-2 |
0.413 |
|
| 2011 |
Cohavy O, Shih DQ, Doherty TM, Ware CF, Targan SR. CD161 DEFINES EFFECTOR T CELLS THAT EXPRESS LIGHT AND RESPOND TO TL1A-DR3 SIGNALING. European Journal of Microbiology & Immunology. 1: 70-79. PMID 22348196 DOI: 10.1556/Eujmi.1.2011.1.9 |
0.354 |
|
| 2011 |
Koon HW, Shih DQ, Hing TC, Chen J, Ho S, Zhao D, Targan SR, Pothoulakis C. Substance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cells. The American Journal of Pathology. 179: 2315-26. PMID 21945803 DOI: 10.1016/J.Ajpath.2011.07.038 |
0.301 |
|
| 2011 |
Koon HW, Shih DQ, Chen J, Bakirtzi K, Hing TC, Law I, Ho S, Ichikawa R, Zhao D, Xu H, Gallo R, Dempsey P, Cheng G, Targan SR, Pothoulakis C. Cathelicidin signaling via the Toll-like receptor protects against colitis in mice. Gastroenterology. 141: 1852-63.e1-3. PMID 21762664 DOI: 10.1053/J.Gastro.2011.06.079 |
0.351 |
|
| 2011 |
Bernstein CN, El-Gabalawy H, Sargent M, Landers CJ, Rawsthorne P, Elias B, Targan SR. Assessing inflammatory bowel disease-associated antibodies in Caucasian and First Nations cohorts Canadian Journal of Gastroenterology. 25: 269-273. PMID 21647462 DOI: 10.1155/2011/712350 |
0.364 |
|
| 2011 |
Kwan LY, Targan SR, Shih DQ. A case of steroid-dependent myeloid granulocytic sarcoma masquerading as Crohn's disease. World Journal of Gastroenterology. 17: 2446-9. PMID 21633646 DOI: 10.3748/Wjg.V17.I19.2446 |
0.337 |
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| 2011 |
Plevy SE, Targan SR. Future therapeutic approaches for inflammatory bowel diseases. Gastroenterology. 140: 1838-46. PMID 21530750 DOI: 10.1053/J.Gastro.2011.02.014 |
0.338 |
|
| 2011 |
Lichtenstein GR, Targan SR, Dubinsky MC, Rotter JI, Barken DM, Princen F, Carroll S, Brown M, Stachelski J, Chuang E, Landers CJ, Stempak JM, Singh S, Silverberg MS. Combination of genetic and quantitative serological immune markers are associated with complicated Crohn's disease behavior. Inflammatory Bowel Diseases. 17: 2488-96. PMID 21391291 DOI: 10.1002/Ibd.21661 |
0.411 |
|
| 2011 |
Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, ... ... Targan SR, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics. 43: 246-52. PMID 21297633 DOI: 10.1038/Ng.764 |
0.371 |
|
| 2011 |
Shih DQ, Barrett R, Zhang X, Yeager N, Koon HW, Phaosawasdi P, Song Y, Ko B, Wong MH, Michelsen KS, Martins G, Pothoulakis C, Targan SR. Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis. Plos One. 6: e16090. PMID 21264313 DOI: 10.1371/Journal.Pone.0016090 |
0.71 |
|
| 2011 |
Haritunians T, Jones MR, McGovern DP, Shih DQ, Barrett RJ, Derkowski C, Dubinsky MC, Dutridge D, Fleshner PR, Ippoliti A, King L, Leshinsky-Silver E, Levine A, Melmed GY, Mengesha E, ... ... Targan SR, et al. Variants in ZNF365 isoform D are associated with Crohn's disease. Gut. 60: 1060-7. PMID 21257989 DOI: 10.1136/Gut.2010.227256 |
0.682 |
|
| 2011 |
Shih DQ, Michelsen KS, Barrett RJ, Biener-Ramanujan E, Gonsky R, Zhang X, Targan SR. Insights into TL1A and IBD pathogenesis. Advances in Experimental Medicine and Biology. 691: 279-88. PMID 21153332 DOI: 10.1007/978-1-4419-6612-4_29 |
0.739 |
|
| 2011 |
Targan SR. Introductory words about TL1A/DR3. Advances in Experimental Medicine and Biology. 691: 271-4. PMID 21153330 DOI: 10.1007/978-1-4419-6612-4_27 |
0.352 |
|
| 2011 |
Yu JE, De Ravin SS, Uzel G, Landers C, Targan S, Malech HL, Holland SM, Cao W, Harpaz N, Mayer L, Cunningham-Rundles C. High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. Clinical Immunology (Orlando, Fla.). 138: 14-22. PMID 20956091 DOI: 10.1016/J.Clim.2010.08.003 |
0.375 |
|
| 2011 |
Gonsky R, Deem RL, Landers CJ, Derkowski CA, Berel D, McGovern DP, Targan SR. Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens. Inflammatory Bowel Diseases. 17: 171-8. PMID 20848535 DOI: 10.1002/Ibd.21352 |
0.426 |
|
| 2011 |
Essers J, Ripke S, Neale B, Xavier R, Targan S, Vu M, Rotter J, Dubinsky M, McGovern D, Daly M. An accurate and reproducible discrimination tool for inflammatory bowel disease subtype using genetics, serologies, and smoking status Inflammatory Bowel Diseases. 17: S1. DOI: 10.1097/00054725-201112002-00002 |
0.335 |
|
| 2011 |
Le Q, Melmed GY, Murrell ZA, Vasiliauskas EA, Shih DQ, Dubinsky M, Ippoliti A, Targan SR, Fleshner P. Factors Associated With Surgical Outcome of Ileal Pouch-Anal Anastomosis When Intentionally Used in Crohn's Disease Gastroenterology. 140: S-785. DOI: 10.1016/S0016-5085(11)63254-X |
0.329 |
|
| 2011 |
White E, Melmed GY, Vasiliauskas EA, Dubinsky M, Ippoliti A, McGovern DP, Shih DQ, Targan SR, Fleshner P. Does Preoperative Immunosuppression Influence Unplanned Hospital Readmission After Surgery in Patients With Crohn's Disease? Gastroenterology. 140: S-770. DOI: 10.1016/S0016-5085(11)63196-X |
0.306 |
|
| 2011 |
Hing TC, Shih DQ, Chen X, Kelly CP, Targan SR, Pothoulakis C, Koon HW. Cathelicidin Modulates Clostridium difficile Toxin a-Mediated Enteritis Gastroenterology. 140: S-634. DOI: 10.1016/S0016-5085(11)62621-8 |
0.364 |
|
| 2011 |
Modiano N, Fleshner P, Taylor KD, Dubinsky M, Vasiliauskas EA, Ippoliti A, Shih DQ, Melmed GY, Targan SR, Berel D, Haritunians T, Rotter JI, McGovern DP. Intestinal Granulomas in Crohn's Disease: Association With Patient Characteristics, Serologic Markers, and Genetics Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)61996-3 |
0.417 |
|
| 2011 |
Chou JY, Vasiliauskas EA, Feldman EJ, Berel D, McGovern DP, Ippoliti A, Dubinsky M, Targan SR, Shih DQ, Nahm M, Ward J, Melmed GY. Immunosuppression Does Not Influence the Decay of Pneumoccal Antibodies 3 Years After Vaccination in Patients With Inflammatory Bowel Disease Gastroenterology. 140: S-426-S-427. DOI: 10.1016/S0016-5085(11)61753-8 |
0.352 |
|
| 2011 |
Nguyen M, Bradford K, Huang BL, Haritunians T, Fleshner P, Himmelfarb E, Landers CJ, Vasiliauskas EA, Ippoliti A, Melmed GY, Dubinsky M, Gonsky R, Rotter JI, Targan SR, McGovern DP, et al. Genetic Predictors of Cytomegalovirus Infection in Patients With Inflammatory Bowel Disease Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)61091-3 |
0.343 |
|
| 2011 |
Taylor KD, Haritunians T, McGovern DP, Landers CJ, Ippoliti A, Vasiliauskas EA, Guo X, Dubinsky M, Targan SR, Rotter JI. Genome-Wide Association Study of CD-Associated Anti-Microbial Antibodies Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)61084-6 |
0.32 |
|
| 2011 |
Essers JB, Cole EB, Dubinsky M, Haritunians T, Korzenik JR, McGovern DP, Sands BE, Targan SR, Taylor KD, Teleten N, Xavier RJ, Daly MJ, Rotter JI, Silverberg MS. The Utility of Genetics in Classifying Ulcerative Colitis and Crohn's Disease Patients Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)61074-3 |
0.397 |
|
| 2011 |
Choi JM, McGovern DP, Lee ES, Berel D, Kwon S, Landers CJ, Haritunians T, Targan SR, Rotter JI, Taylor KD, Dubinsky M. Predictors of Therapeutic Remission to Thiopurines in Pediatric Inflammatory Bowel Disease Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60623-9 |
0.413 |
|
| 2011 |
Siegel CA, Fleshner P, Siegel LS, Rotter JI, Dubinsky M, Vasiliauskas EA, Ippoliti A, Shih DQ, Melmed GY, Landers CJ, Haritunians T, Targan SR, Taylor KD, McGovern DP. Predicting Crohn's Disease Post-Operative Recurrence Using Clinical, Endoscopic, Serologic and Genetic Factors Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60622-7 |
0.324 |
|
| 2011 |
Dubinsky M, Kugathasan S, Kwon S, Haritunians T, Wrobel IT, Wahbeh G, Quiros A, Bahar RJ, Farrior S, Teleten N, Panikkath D, Ippoliti A, Fleshner P, Williams CI, Landers CJ, ... Targan SR, et al. A Combination of Genetic, Clinical and Immune Markers Predict the Need for Surgery in Crohn's Disease Gastroenterology. 140: S-153. DOI: 10.1016/S0016-5085(11)60621-5 |
0.329 |
|
| 2011 |
Barrett R, Zhang X, Yeager N, Koon HW, Nguyen MA, Phaosawasdi P, Li C, Pothoulakis C, Targan SR, Shih DQ. In Vivo Constitutive Expression of an IBD Associated Gene TNFSF15 Causes Severe Inflammation and Induces Fibrostenotic Disease in 2 Murine Models of Chronic Colitis Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60612-4 |
0.683 |
|
| 2011 |
Sandborn WJ, Gasink C, Gao L, Blank M, Johanns J, Guzzo C, Sands BE, Hanauer SB, Targan SR, Rutgeerts PJ, Ghosh S, de Villiers W, Panaccione R, Greenberg GR, Schreiber S, et al. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase2b Study of Ustekinumab, a Human Monoclonal Antibody to IL-12/23p40, in Patients With Moderately to Severely Active Crohn's Disease: Results Through Week 22 From the Certifi Trial Gastroenterology. 140: S-109. DOI: 10.1016/S0016-5085(11)60443-5 |
0.364 |
|
| 2011 |
deFonseka AM, Haritunians T, Berel D, Targan SR, Landers CJ, Rotter JI, Vasiliauskas EA, Ippoliti A, Melmed GY, Shih DQ, Dubinsky M, Taylor KD, McGovern DP. Clinical, Serologic, and Genetic Associations With Low Bone Density in Patients With Inflammatory Bowel Disease Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60021-8 |
0.358 |
|
| 2010 |
Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, ... ... Targan SR, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature Genetics. 42: 1118-25. PMID 21102463 DOI: 10.1038/Ng.717 |
0.334 |
|
| 2010 |
Sandborn WJ, Colombel JF, Frankel M, Hommes D, Lowder JN, Mayer L, Plevy S, Stokkers P, Travis S, Van Assche G, Baumgart DC, Targan SR. Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis. Gut. 59: 1485-92. PMID 20947884 DOI: 10.1136/Gut.2009.205443 |
0.343 |
|
| 2010 |
Haritunians T, Taylor KD, Targan SR, Dubinsky M, Ippoliti A, Kwon S, Guo X, Melmed GY, Berel D, Mengesha E, Psaty BM, Glazer NL, Vasiliauskas EA, Rotter JI, Fleshner PR, et al. Genetic predictors of medically refractory ulcerative colitis. Inflammatory Bowel Diseases. 16: 1830-40. PMID 20848476 DOI: 10.1002/Ibd.21293 |
0.344 |
|
| 2010 |
McGovern DP, Jones MR, Taylor KD, Marciante K, Yan X, Dubinsky M, Ippoliti A, Vasiliauskas E, Berel D, Derkowski C, Dutridge D, Fleshner P, Shih DQ, Melmed G, Mengesha E, ... ... Targan SR, et al. Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. Human Molecular Genetics. 19: 3468-76. PMID 20570966 DOI: 10.1093/Hmg/Ddq248 |
0.343 |
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| 2010 |
Biener-Ramanujan E, Gonsky R, Ko B, Targan SR. Functional signaling of membrane-bound TL1A induces IFN-gamma expression. Febs Letters. 584: 2376-80. PMID 20403353 DOI: 10.1016/J.Febslet.2010.04.030 |
0.35 |
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| 2010 |
McGovern DP, Gardet A, Törkvist L, Goyette P, Essers J, Taylor KD, Neale BM, Ong RT, Lagacé C, Li C, Green T, Stevens CR, Beauchamp C, Fleshner PR, Carlson M, ... ... Targan SR, et al. Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nature Genetics. 42: 332-7. PMID 20228799 DOI: 10.1038/Ng.549 |
0.389 |
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| 2010 |
Melmed GY, Targan SR. Future biologic targets for IBD: potentials and pitfalls. Nature Reviews. Gastroenterology & Hepatology. 7: 110-7. PMID 20134493 DOI: 10.1038/Nrgastro.2009.218 |
0.321 |
|
| 2010 |
Ippoliti A, Devlin S, Mei L, Yang H, Papadakis KA, Vasiliauskas EA, McGovern DP, Abreu MT, Melmed G, Shaye O, Enayati P, Chen G, Choi J, Taylor K, Landers CJ, ... ... Targan SR, et al. Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease. Inflammatory Bowel Diseases. 16: 1279-85. PMID 20027650 DOI: 10.1002/Ibd.21196 |
0.422 |
|
| 2010 |
Dubinsky MC, Mei L, Friedman M, Dhere T, Haritunians T, Hakonarson H, Kim C, Glessner J, Targan SR, McGovern DP, Taylor KD, Rotter JI. Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 16: 1357-66. PMID 20014019 DOI: 10.1002/Ibd.21174 |
0.416 |
|
| 2010 |
Melmed GY, Agarwal N, Frenck RW, Ippoliti AF, Ibanez P, Papadakis KA, Simpson P, Barolet-Garcia C, Ward J, Targan SR, Vasiliauskas EA. Immunosuppression impairs response to pneumococcal polysaccharide vaccination in patients with inflammatory bowel disease. The American Journal of Gastroenterology. 105: 148-54. PMID 19755964 DOI: 10.1038/Ajg.2009.523 |
0.334 |
|
| 2010 |
Baumgart DC, Targan SR, Dignass AU, Mayer L, van Assche G, Hommes DW, Hanauer SB, Mahadevan U, Reinisch W, Plevy SE, Salzberg BA, Buchman AL, Mechkov GM, Krastev ZA, Lowder JN, et al. Prospective randomized open-label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid-refractory ulcerative colitis. Inflammatory Bowel Diseases. 16: 620-9. PMID 19714757 DOI: 10.1002/Ibd.21084 |
0.32 |
|
| 2010 |
Jones MR, Haritunians T, McGovern DP, Dubinsky M, Ippoliti A, Vasiliauskas EA, Melmed GY, Shih DQ, Fleshner P, Levine A, Leshinsky ES, Siscovick D, Marciante KD, Targan SR, Rotter JI, et al. W1213 Genome Wide Association Study in Ashkenazi Jewish Crohn's Disease Patients Reveals Novel Susceptibility Loci Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63106-X |
0.363 |
|
| 2010 |
Bernstein CN, El-Gabalawy H, Sargent M, Landers CJ, Elias B, Targan SR. T1274 Assessing IBD-Associated Antibodies in Caucasian and First Nation Cohorts-Clue to the Paucity of IBD in First Nations? Gastroenterology. 138: S-526. DOI: 10.1016/S0016-5085(10)62429-8 |
0.306 |
|
| 2010 |
Brelian D, McGovern DP, Dubinsky M, Berel D, Shih DQ, Ippoliti A, Vasiliauskas EA, Targan SR, Fleshner P, Melmed GY. S1187 Unique Predictors of Chronic Pouch Inflammation Among Ulcerative Colitis Patients With Primary Sclerosing Cholangitis (PSC) Undergoing Ileal Pouch-Anal Anastomosis (IPAA) Gastroenterology. 138: S-199-S-200. DOI: 10.1016/S0016-5085(10)60903-1 |
0.354 |
|
| 2010 |
Nguyen M, Bradford K, Zhang X, Simpson P, Targan SR, Vasiliauskas EA, Shih DQ. 1004 Severity of Cytomegalovirus Infection on Pathology Specimens is Associated With Colectomy Rates and Response to Antiviral Therapy in Inflammatory Bowel Disease Patients Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)60663-4 |
0.379 |
|
| 2010 |
Cheng-Robles D, Melmed GY, Vasiliauskas EA, Dubinsky M, McGovern DP, Ippoliti A, Shih DQ, Targan SR, Fleshner P. 489 Preoperative pANCA Expression Influences the Outcome of Ileal Pouch-Anastomosis in Inflammatory Bowel Disease-Unclassified (IBDU) Gastroenterology. 138: S-69. DOI: 10.1016/S0016-5085(10)60315-0 |
0.382 |
|
| 2010 |
Lichtenstein G, Barken DM, Eggleston L, Princen F, Brown MP, Stachelski J, Nguyen A, Chuang E, Carroll S, Singh S, Hughes P, Silverberg MS, Dubinsky M, Targan SR. 207 A Novel Algorithm-Based Approach Using Clinical Parameters, Genetic and Serological Markers to Effectively Predict Aggressive Disease Behavior in Patients With Crohn's Disease Gastroenterology. 138: S-38-S-39. DOI: 10.1016/S0016-5085(10)60177-1 |
0.342 |
|
| 2010 |
Shih DQ, Barrett R, Zhang X, Ko B, Wong MH, Phaosawasdi P, Yeager N, Martins G, Takedatsu H, Michelsen KS, Targan SR. 85 Constitutive In Vivo Expression of TNFSF15 in Myeloid or Lymphoid Cells Induce Mild Small Bowel Inflammation in Mice Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)60068-6 |
0.672 |
|
| 2010 |
Haritunians T, Jones MR, McGovern DP, Fleshner P, Ippoliti A, Dubinsky M, Vasiliauskas EA, Melmed GY, Shih DQ, Barrett R, Rotter JI, Targan SR, Taylor KD. 30 Variants in Znf365 on 10q21 are Associated With Crohn's Disease Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)60024-8 |
0.67 |
|
| 2010 |
Yu J, DeRavin S, Uzel G, Mayer L, Targan S, Malech H, Holland S, Cunningham-Rundles C. Microbial Antigen Sensitization and Colitis in Chronic Granulomatous Disease and Hyper IgE Syndrome Journal of Allergy and Clinical Immunology. 125: AB9. DOI: 10.1016/J.Jaci.2009.12.065 |
0.337 |
|
| 2010 |
Karp LC, Targan SR. Heterogeneity of Inflammatory Bowel Diseases Inflammatory Bowel Disease: Translating Basic Science Into Clinical Practice. 3-8. DOI: 10.1002/9781444318418.ch2 |
0.326 |
|
| 2009 |
Mundwiler ML, Mei L, Landers CJ, Reveille JD, Targan S, Weisman MH. Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study. Arthritis Research & Therapy. 11: R177. PMID 19930665 DOI: 10.1186/Ar2866 |
0.367 |
|
| 2009 |
Shih DQ, Targan SR. Insights into IBD Pathogenesis. Current Gastroenterology Reports. 11: 473-80. PMID 19903423 DOI: 10.1007/S11894-009-0072-9 |
0.416 |
|
| 2009 |
Shih DQ, Kwan LY, Chavez V, Cohavy O, Gonsky R, Chang EY, Chang C, Elson CO, Targan SR. Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells. European Journal of Immunology. 39: 3239-50. PMID 19839006 DOI: 10.1002/Eji.200839087 |
0.43 |
|
| 2009 |
Nasseri Y, Melmed G, Wang HL, Targan S, Fleshner P. Rigorous histopathological assessment of the colectomy specimen in patients with inflammatory bowel disease unclassified does not predict outcome after ileal pouch-anal anastomosis. The American Journal of Gastroenterology. 105: 155-61. PMID 19755970 DOI: 10.1038/Ajg.2009.510 |
0.418 |
|
| 2009 |
Saruta M, Michelsen KS, Thomas LS, Yu QT, Landers CJ, Targan SR. TLR8-mediated activation of human monocytes inhibits TL1A expression European Journal of Immunology. 39: 2195-2202. PMID 19637197 DOI: 10.1002/Eji.200939216 |
0.368 |
|
| 2009 |
Murrell ZA, Melmed GY, Ippoliti A, Vasiliauskas EA, Dubinsky M, Targan SR, Fleshner PR. A prospective evaluation of the long-term outcome of ileal pouch-anal anastomosis in patients with inflammatory bowel disease-unclassified and indeterminate colitis. Diseases of the Colon and Rectum. 52: 872-8. PMID 19502850 DOI: 10.1007/Dcr.0B013E31819F5D4C |
0.313 |
|
| 2009 |
Michelsen KS, Thomas LS, Taylor KD, Yu QT, Mei L, Landers CJ, Derkowski C, McGovern DP, Rotter JI, Targan SR. IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein. Plos One. 4: e4719. PMID 19262684 DOI: 10.1371/Journal.Pone.0004719 |
0.422 |
|
| 2009 |
Baumgart DC, Lowder JN, Targan SR, Sandborn WJ, Frankel MB. Transient cytokine-induced liver injury following administration of the humanized anti-CD3 antibody visilizumab (HuM291) in Crohn's disease. The American Journal of Gastroenterology. 104: 868-76. PMID 19240707 DOI: 10.1038/Ajg.2008.138 |
0.371 |
|
| 2009 |
McGovern DP, Rotter JI, Mei L, Haritunians T, Landers C, Derkowski C, Dutridge D, Dubinsky M, Ippoliti A, Vasiliauskas E, Mengesha E, King L, Pressman S, Targan SR, Taylor KD. Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease. Inflammatory Bowel Diseases. 15: 883-9. PMID 19235914 DOI: 10.1002/Ibd.20855 |
0.345 |
|
| 2009 |
Markowitz J, Kugathasan S, Dubinsky M, Mei L, Crandall W, LeLeiko N, Oliva-Hemker M, Rosh J, Evans J, Mack D, Otley A, Pfefferkorn M, Bahar R, Vasiliauskas E, Wahbeh G, ... ... Targan S, et al. Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology? Inflammatory Bowel Diseases. 15: 714-9. PMID 19107777 DOI: 10.1002/Ibd.20831 |
0.352 |
|
| 2009 |
Saruta M, Targan SR, Mei L, Ippoliti AF, Taylor KD, Rotter JI. High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females. Inflammatory Bowel Diseases. 15: 321-7. PMID 18942751 DOI: 10.1002/Ibd.20754 |
0.374 |
|
| 2009 |
Takedatsu H, Taylor KD, Mei L, McGovern DP, Landers CJ, Gonsky R, Cong Y, Vasiliauskas EA, Ippoliti A, Elson CO, Rotter JI, Targan SR. Linkage of Crohn's disease-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-kappaB activation. Gut. 58: 60-7. PMID 18832525 DOI: 10.1136/Gut.2008.156422 |
0.395 |
|
| 2009 |
McGovern DP, Taylor KD, Landers C, Derkowski C, Dutridge D, Dubinsky M, Ippoliti A, Vasiliauskas E, Mei L, Mengesha E, King L, Pressman S, Targan SR, Rotter JI. MAGI2 genetic variation and inflammatory bowel disease. Inflammatory Bowel Diseases. 15: 75-83. PMID 18720471 DOI: 10.1002/Ibd.20611 |
0.38 |
|
| 2009 |
Fleshner P, Cheng-Robles D, Vasiliauskas E, Melmed G, Dubinsky M, Ippoliti A, McGovern D, Targan S. Is There Any Association Between Clinical Features or IBD Seromarker Expression and the Efficacy of Aggressive Medical Therapy of de novo Crohnʼs Disease after Ileal Pouch-Anal Anastomosis? American Journal of Gastroenterology. 104: S472-S473. DOI: 10.14309/00000434-200910003-01264 |
0.319 |
|
| 2009 |
Kwan L, Dhall D, Lopategui J, Targan S, Shih D. Small Bowel Malignancies Mimicking as IBD Flares American Journal of Gastroenterology. 104: S465-S466. DOI: 10.14309/00000434-200910003-01246 |
0.339 |
|
| 2009 |
Dai S, Fleshner P, Vasiliauskas EA, Ippoliti A, McGovern DP, Targan SR, Melmed GY. W1133 Adalimumab May Provide Short-Term Improvement in Bowel Movement Frequency for de novo Crohn's Disease After Ileal-Pouch Anal Anastomosis Gastroenterology. 136: A-661. DOI: 10.1016/S0016-5085(09)63047-X |
0.318 |
|
| 2009 |
Cohavy O, Shih DQ, Doherty TM, Ware C, Targan SR. S1678 CD161 Defines Effector T Cell Population That Express Light, Respond to TL1A-DR3 Signaling, and Activates Antigen Presenting Cells Gastroenterology. 136: A-248. DOI: 10.1016/S0016-5085(09)61124-0 |
0.32 |
|
| 2009 |
Haritunians T, Taylor KD, Rotter JI, Ippoliti A, Dubinsky M, Vasiliauskas EA, Melmed GY, Psaty BM, Targan SR, Fleshner P, McGovern DP. 857 Genetic Predictors of Medically Refractive Ulcerative Colitis (UC) Requiring Colectomy Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60586-2 |
0.376 |
|
| 2009 |
Wang HL, Tsuchihashi Z, Targan SR, Parker SM, Siegel J, Berman D. 79 Ipilimumab-Related Colitis in Patients with Advanced Melanoma Receiving Ipilimumab Therapy: Histopathologic and Serologic Characterization Gastroenterology. 136: A-14. DOI: 10.1016/S0016-5085(09)60069-X |
0.316 |
|
| 2008 |
Shih DQ, Targan SR, McGovern D. Recent advances in IBD pathogenesis: genetics and immunobiology. Current Gastroenterology Reports. 10: 568-75. PMID 19006613 DOI: 10.1007/S11894-008-0104-X |
0.387 |
|
| 2008 |
Shen C, Landers CJ, Derkowski C, Elson CO, Targan SR. Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease. Inflammatory Bowel Diseases. 14: 1641-51. PMID 18825772 DOI: 10.1002/Ibd.20645 |
0.385 |
|
| 2008 |
Brewer S, McPherson M, Fujiwara D, Turovskaya O, Ziring D, Chen L, Takedatsu H, Targan SR, Wei B, Braun J. Molecular imaging of murine intestinal inflammation with 2-deoxy-2-[18F]fluoro-D-glucose and positron emission tomography. Gastroenterology. 135: 744-55. PMID 18639553 DOI: 10.1053/J.Gastro.2008.06.040 |
0.311 |
|
| 2008 |
Dubinsky MC, Kugathasan S, Mei L, Picornell Y, Nebel J, Wrobel I, Quiros A, Silber G, Wahbeh G, Katzir L, Vasiliauskas E, Bahar R, Otley A, Mack D, Evans J, ... ... Targan SR, et al. Increased immune reactivity predicts aggressive complicating Crohn's disease in children. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 6: 1105-11. PMID 18619921 DOI: 10.1016/J.Cgh.2008.04.032 |
0.373 |
|
| 2008 |
Takedatsu H, Michelsen KS, Wei B, Landers CJ, Thomas LS, Dhall D, Braun J, Targan SR. TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation. Gastroenterology. 135: 552-67. PMID 18598698 DOI: 10.1053/J.Gastro.2008.04.037 |
0.354 |
|
| 2008 |
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, ... ... Targan SR, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nature Genetics. 40: 955-62. PMID 18587394 DOI: 10.1038/Ng.175 |
0.356 |
|
| 2008 |
Fleshner P, Ippoliti A, Dubinsky M, Vasiliauskas E, Mei L, Papadakis KA, Rotter JI, Landers C, Targan S. Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 6: 561-8. PMID 18378498 DOI: 10.1016/J.Cgh.2008.01.002 |
0.331 |
|
| 2008 |
Mitsuhashi M, Targan SR. Ex vivo simulation of IgG Fc and T-cell receptor functions: an application to inflammatory bowel disease. Inflammatory Bowel Diseases. 14: 1061-7. PMID 18340639 DOI: 10.1002/Ibd.20428 |
0.355 |
|
| 2008 |
Shih DQ, Targan SR. Immunopathogenesis of inflammatory bowel disease. World Journal of Gastroenterology. 14: 390-400. PMID 18200661 DOI: 10.3748/Wjg.14.390 |
0.425 |
|
| 2008 |
Melmed GY, Fleshner PR, Bardakcioglu O, Ippoliti A, Vasiliauskas EA, Papadakis KA, Dubinsky M, Landers C, Rotter JI, Targan SR. Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitis. Diseases of the Colon and Rectum. 51: 100-8. PMID 18085333 DOI: 10.1007/S10350-007-9158-3 |
0.393 |
|
| 2008 |
Vandewalle-El Khoury P, Colombel JF, Joossens S, Standaert-Vitse A, Collot M, Halfvarson J, Ayadi A, Landers CJ, Vermeire S, Rutgeerts P, Targan SR, Chamaillard M, Mallet JM, Sendid B, Poulain D. Detection of antisynthetic mannoside antibodies (ASigmaMA) reveals heterogeneity in the ASCA response of Crohn's disease patients and contributes to differential diagnosis, stratification, and prediction. The American Journal of Gastroenterology. 103: 949-57. PMID 18047546 DOI: 10.1111/J.1572-0241.2007.01648.X |
0.319 |
|
| 2008 |
DEEM RL, SHANAHAN F, TARGAN SR. Triggered human mucosal T cells release tumour necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells Clinical & Experimental Immunology. 83: 79-84. DOI: 10.1111/J.1365-2249.1991.Tb05592.X |
0.338 |
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| 2008 |
DEEM RL, TARGAN SR, NIEDERLEHNER A, SHANAHAN F. The CD8+ Leu-7+ subset of T cells in Crohn's disease: distinction between cytotoxic and covert suppressor functions Clinical & Experimental Immunology. 80: 387-394. DOI: 10.1111/J.1365-2249.1990.Tb03298.X |
0.387 |
|
| 2008 |
Takedatsu H, Michelsen KS, Landers CJ, Thomas LS, Targan SR. W1179 TL1A (TNFSF15) Enhances the Activation of TH17 Cells During Chronic Intestinal Inflammation Gastroenterology. 134: A-649-A-650. DOI: 10.1016/S0016-5085(08)63031-0 |
0.333 |
|
| 2008 |
Gonsky R, Deem RL, Targan SR. W1178 Unique Epigenetic Modification of IFNG in Inflammatory Bowel Disease Is Linked to Functional Expression in the Mucosa Gastroenterology. 134: A-649. DOI: 10.1016/S0016-5085(08)63030-9 |
0.394 |
|
| 2008 |
Saruta M, Michelsen KS, Yu Q, Thomas LS, Landers CJ, Targan SR. T1202 TLR8 Signaling Inhibits the Expression of the IBD-Associated Cytokine TL1A (TNFSF15) in Human Monocytes Gastroenterology. 134: A-506. DOI: 10.1016/S0016-5085(08)62360-4 |
0.313 |
|
| 2008 |
Melmed GY, Wang HL, Vasiliauskas EA, Dubinsky MC, Ippoliti A, McGovern DP, Targan SR, Fleshner P. T1174 What Is the Natural History of Inflammatory Bowel Disease-Unclassified (IBDU) After Ileal Pouch Anal Anastomosis (IPAA)? Gastroenterology. 134: A-500. DOI: 10.1016/S0016-5085(08)62333-1 |
0.39 |
|
| 2008 |
Ziring DA, Taylor KD, Rotter JI, Targan SR, Braun J. M2067 Candidate Gene Approach Identifies CNR2 Gene As Associated with Crohn's Disease: Assigned Haplotypes, Protein Expression, and Functional Data As Defined By Novel Use of Lymphoblastoid Cell Lines Gastroenterology. 134: A-462. DOI: 10.1016/S0016-5085(08)62160-5 |
0.318 |
|
| 2008 |
McGovern DP, Targan SR, Mei L, Dubinsky MC, Mengesha E, Landers CJ, Rotter JI, Taylor KD. M2063 IBD4: the EFS Knockout Mouse Model of Ileal Inflammation Leads to a Positive Association of the Human EFS Gene with Anti-CBIR1 Positive CD Gastroenterology. 134: A-461. DOI: 10.1016/S0016-5085(08)62156-3 |
0.336 |
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| 2008 |
Su X, Mei L, Landers CJ, Braun J, Ziring DA, Targan SR, Taylor KD, Rotter JI. M2060 Haplotypes of the CNR2 Gene Are Associated with Different Sero-Reactivity to Microbial Antigens in Patients with Crohn's Disease Gastroenterology. 134: A-460. DOI: 10.1016/S0016-5085(08)62153-8 |
0.365 |
|
| 2008 |
Mei L, Taylor KD, McGovern DP, Picornell Y, Su X, Landers CJ, Targan SR, Rotter JI. M2057 Variants in Genes Related to Innate (NOD2, TLR5) and Adaptive (TNFSF15/TL1A) Immune Pathways Combine to Increase the Magnitude of Anti-OmpC Expression in Jewish CD Subjects Gastroenterology. 134: A-460. DOI: 10.1016/S0016-5085(08)62150-2 |
0.307 |
|
| 2008 |
Ibanez P, Pimentel M, Melmed GY, Ippoliti A, Targan SR, Vasiliauskas EA. M1154 Fatigue and Abdominal Bloating Predict Small Intestinal Bacterial Overgrowth (SIBO) in Patients with Ulcerative Colitis (UC) Gastroenterology. 134: A-350. DOI: 10.1016/S0016-5085(08)61630-3 |
0.311 |
|
| 2008 |
Takedatsu H, Michelsen KS, Landers CJ, Thomas LS, Dhall D, Targan SR. S1746 IL-23 Is Only Partially Involved in Promoting Chronic Intestinal Inflammation in the Dextran Sodium Sulphate-Induced Colitis Model Gastroenterology. 134: A-262. DOI: 10.1016/S0016-5085(08)61217-2 |
0.326 |
|
| 2008 |
McGovern DP, Taylor KD, Landers CJ, Dutridge D, Derkowski CA, Mei L, Ippoliti A, Vasiliauskas EA, Dubinsky MC, Rotter JI, Targan SR, Fleshner P. S1210 Clinical, Serological and Genetic Predictors of Postoperative Recurrence in a Single-Center Prospectively Collected Cohort of Crohn's Disease Patients Gastroenterology. 134: A-202. DOI: 10.1016/S0016-5085(08)60932-4 |
0.364 |
|
| 2008 |
Melmed GY, Frenck R, Barolet-Garcia C, Ibanez P, Simpson P, Papadakis KA, Ward J, Ippoliti A, Targan SR, Vasiliauskas EA. 495 TNF Blockers and Immunomodulators Impair Antibody Responses to Pneumococcal Polysaccharide Vaccine (Ppv) in Patients with Inflammatory Bowel Disease (IBD) Gastroenterology. 134: A-68. DOI: 10.1016/S0016-5085(08)60319-4 |
0.372 |
|
| 2008 |
Mei L, Taylor KD, Landers CJ, McGovern DP, Targan SR, Rotter JI. 300 Genetic Variation in BTLA Is Strongly Associated with Crohn's Disease Gastroenterology. 134: A-42. DOI: 10.1016/S0016-5085(08)60203-6 |
0.352 |
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| 2008 |
Shih DQ, Kwan LY, Chang EY, Chang C, Saruta M, Elson CO, Targan SR. 132 Mechanism of Induction of Inflammatory Bowel Disease Associated Gene TL1A (TNFSF15) By Microbes in Antigen Presenting Cells Gastroenterology. 134: A-23. DOI: 10.1016/S0016-5085(08)60114-6 |
0.348 |
|
| 2008 |
Takedatsu H, Michelsen KS, Wei B, Landers CJ, Thomas LS, Dhall D, Braun J, Targan SR. 25 TL1A (TNFSF15) Is Involved in the Pathogenesis of Two T Cell-Mediated Chronic Colitis Models Through Modulation of Both TH1 and TH17 Activation Gastroenterology. 134: A-3. DOI: 10.1016/S0016-5085(08)60021-9 |
0.401 |
|
| 2008 |
Michelsen KS, Thomas LS, Taylor KD, Yu Q, Mei L, Landers CJ, Derkowski CA, Rotter JI, Targan SR. 24 TL1A (TNFSF15) Haplotypes Associated with Severe Crohn's Disease (CD) Determine Increased Protein Expression Gastroenterology. 134: A-2-A-3. DOI: 10.1016/S0016-5085(08)60020-7 |
0.38 |
|
| 2007 |
Plevy S, Salzberg B, Van Assche G, Regueiro M, Hommes D, Sandborn W, Hanauer S, Targan S, Mayer L, Mahadevan U, Frankel M, Lowder J. A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. Gastroenterology. 133: 1414-22. PMID 17920064 DOI: 10.1053/J.Gastro.2007.08.035 |
0.348 |
|
| 2007 |
Schluender SJ, Ippoliti A, Dubinsky M, Vasiliauskas EA, Papadakis KA, Mei L, Targan SR, Fleshner PR. Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis? Diseases of the Colon and Rectum. 50: 1747-53. PMID 17704969 DOI: 10.1007/S10350-007-9008-3 |
0.312 |
|
| 2007 |
Clark M, Colombel JF, Feagan BC, Fedorak RN, Hanauer SB, Kamm MA, Mayer L, Regueiro C, Rutgeerts P, Sandborn WJ, Sands BE, Schreiber S, Targan S, Travis S, Vermeire S. American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. Gastroenterology. 133: 312-39. PMID 17631151 DOI: 10.1053/J.Gastro.2007.05.006 |
0.348 |
|
| 2007 |
Targan SR, Karp LC. Inflammatory bowel disease diagnosis, evaluation and classification: state-of-the art approach. Current Opinion in Gastroenterology. 23: 390-4. PMID 17545774 DOI: 10.1097/Mog.0B013E3281722271 |
0.369 |
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| 2007 |
Targan SR, Feagan BG, Fedorak RN, Lashner BA, Panaccione R, Present DH, Spehlmann ME, Rutgeerts PJ, Tulassay Z, Volfova M, Wolf DC, Hernandez C, Bornstein J, Sandborn WJ. Natalizumab for the Treatment of Active Crohn's Disease: Results of the ENCORE Trial Gastroenterology. 132: 1672-1683. PMID 17484865 DOI: 10.1053/J.Gastro.2007.03.024 |
0.355 |
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| 2007 |
Melmed GY, Elashoff R, Chen GC, Nastaskin I, Papadakis KA, Vasiliauskas EA, Liu W, Landers C, Ippoliti AF, Targan SR. Predicting a change in diagnosis from ulcerative colitis to Crohn's disease: a nested, case-control study. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 5: 602-8; quiz 525. PMID 17478347 DOI: 10.1016/J.Cgh.2007.02.015 |
0.335 |
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| 2007 |
Cohavy O, Targan SR. CD56 marks an effector T cell subset in the human intestine. Journal of Immunology (Baltimore, Md. : 1950). 178: 5524-32. PMID 17442934 DOI: 10.4049/Jimmunol.178.9.5524 |
0.351 |
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| 2007 |
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nature Genetics. 39: 596-604. PMID 17435756 DOI: 10.1038/Ng2032 |
0.377 |
|
| 2007 |
Prehn JL, Thomas LS, Landers CJ, Yu QT, Michelsen KS, Targan SR. The T cell costimulator TL1A is induced by FcγR signaling in human monocytes and dendritic cells Journal of Immunology. 178: 4033-4038. PMID 17371957 DOI: 10.4049/Jimmunol.178.7.4033 |
0.358 |
|
| 2007 |
Saruta M, Yu QT, Avanesyan A, Fleshner PR, Targan SR, Papadakis KA. Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease. Journal of Immunology (Baltimore, Md. : 1950). 178: 3293-300. PMID 17312180 DOI: 10.4049/Jimmunol.178.5.3293 |
0.386 |
|
| 2007 |
Dubinsky MC, Wang D, Picornell Y, Wrobel I, Katzir L, Quiros A, Dutridge D, Wahbeh G, Silber G, Bahar R, Mengesha E, Targan SR, Taylor KD, Rotter JI. IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflammatory Bowel Diseases. 13: 511-5. PMID 17309073 DOI: 10.1002/Ibd.20126 |
0.314 |
|
| 2007 |
Papadakis KA, Yang H, Ippoliti A, Mei L, Elson CO, Hershberg RM, Vasiliauskas EA, Fleshner PR, Abreu MT, Taylor K, Landers CJ, Rotter JI, Targan SR. Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations. Inflammatory Bowel Diseases. 13: 524-30. PMID 17260364 DOI: 10.1002/Ibd.20106 |
0.431 |
|
| 2007 |
Devlin SM, Yang H, Ippoliti A, Taylor KD, Landers CJ, Su X, Abreu MT, Papadakis KA, Vasiliauskas EA, Melmed GY, Fleshner PR, Mei L, Rotter JI, Targan SR. NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives. Gastroenterology. 132: 576-86. PMID 17258734 DOI: 10.1053/J.Gastro.2006.11.013 |
0.374 |
|
| 2007 |
Picornell Y, Mei L, Taylor K, Yang H, Targan SR, Rotter JI. TNFSF15 is an ethnic-specific IBD gene Inflammatory Bowel Diseases. 13: 1333-1338. DOI: 10.1002/Ibd.20223 |
0.355 |
|
| 2006 |
Spivak J, Landers CJ, Vasiliauskas EA, Abreu MT, Dubinsky MC, Papadakis KA, Ippoliti A, Targan SR, Fleshner PR. Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease. Inflammatory Bowel Diseases. 12: 1122-30. PMID 17119386 DOI: 10.1097/01.Mib.0000235833.47423.D7 |
0.376 |
|
| 2006 |
Kucharzik T, Maaser C, Lügering A, Kagnoff M, Mayer L, Targan S, Domschke W. Recent understanding of IBD pathogenesis: implications for future therapies. Inflammatory Bowel Diseases. 12: 1068-83. PMID 17075348 DOI: 10.1097/01.Mib.0000235827.21778.D5 |
0.43 |
|
| 2006 |
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (New York, N.Y.). 314: 1461-3. PMID 17068223 DOI: 10.1126/Science.1135245 |
0.438 |
|
| 2006 |
Elson CO, Cong Y, Qi F, Hershberg RM, Targan SR. Molecular approaches to the role of the microbiota in inflammatory bowel disease. Annals of the New York Academy of Sciences. 1072: 39-51. PMID 17057189 DOI: 10.1196/Annals.1326.010 |
0.42 |
|
| 2006 |
Melmed GY, Ippoliti AF, Papadakis KA, Tran TT, Birt JL, Lee SK, Frenck RW, Targan SR, Vasiliauskas EA. Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses. The American Journal of Gastroenterology. 101: 1834-40. PMID 16817843 DOI: 10.1111/J.1572-0241.2006.00646.X |
0.358 |
|
| 2006 |
Dubinsky MC, Taylor K, Targan SR, Rotter JI. Immunogenetic phenotypes in inflammatory bowel disease. World Journal of Gastroenterology. 12: 3645-50. PMID 16773679 DOI: 10.3748/Wjg.V12.I23.3645 |
0.429 |
|
| 2006 |
Braun J, Targan SR. Multiparameter analysis of immunogenetic mechanisms in clinical diagnosis and management of inflammatory bowel disease. Advances in Experimental Medicine and Biology. 579: 209-18. PMID 16620020 DOI: 10.1007/0-387-33778-4_13 |
0.366 |
|
| 2006 |
Mei L, Targan SR, Landers CJ, Dutridge D, Ippoliti A, Vasiliauskas EA, Papadakis KA, Fleshner PR, Rotter JI, Yang H. Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease. Gastroenterology. 130: 1078-85. PMID 16618402 DOI: 10.1053/J.Gastro.2006.02.013 |
0.359 |
|
| 2006 |
Dubinsky MC, Lin YC, Dutridge D, Picornell Y, Landers CJ, Farrior S, Wrobel I, Quiros A, Vasiliauskas EA, Grill B, Israel D, Bahar R, Christie D, Wahbeh G, Silber G, ... ... Targan SR, et al. Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression. The American Journal of Gastroenterology. 101: 360-7. PMID 16454844 DOI: 10.1111/J.1572-0241.2006.00456.X |
0.404 |
|
| 2006 |
Abreu MT, Geller JL, Vasiliauskas EA, Kam LY, Vora P, Martyak LA, Yang H, Hu B, Lin YC, Keenan G, Price J, Landers CJ, Adams JS, Targan SR. Treatment with infliximab is associated with increased markers of bone formation in patients with Crohn's disease. Journal of Clinical Gastroenterology. 40: 55-63. PMID 16340635 DOI: 10.1097/01.Mcg.0000190762.80615.D4 |
0.326 |
|
| 2006 |
TARGAN SR. Current Limitations of IBD Treatment: Where Do We Go from Here? Annals of the New York Academy of Sciences. 1072: 1-8. DOI: 10.1196/Annals.1326.032 |
0.384 |
|
| 2005 |
Sandborn WJ, Colombel JF, Enns R, Feagan BG, Hanauer SB, Lawrance IC, Panaccione R, Sanders M, Schreiber S, Targan S, van Deventer S, Goldblum R, Despain D, Hogge GS, Rutgeerts P, et al. Natalizumab induction and maintenance therapy for Crohn's disease. The New England Journal of Medicine. 353: 1912-25. PMID 16267322 DOI: 10.1056/Nejmoa043335 |
0.323 |
|
| 2005 |
Isaacs KL, Lewis JD, Sandborn WJ, Sands BE, Targan SR, Merrick M. State of the art: IBD therapy and clinical trials in IBD Inflammatory Bowel Diseases. 11. PMID 16254481 DOI: 10.1097/01.Mib.0000184852.84558.B2 |
0.443 |
|
| 2005 |
Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, Brant SR, Caprilli R, Colombel JF, Gasche C, Geboes K, Jewell DP, Karban A, Loftus EV, Peña AS, Riddell RH, ... ... Targan SR, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 19: 5A-36A. PMID 16151544 DOI: 10.1155/2005/269076 |
0.353 |
|
| 2005 |
Targan SR, Karp LC. Defects in mucosal immunity leading to ulcerative colitis. Immunological Reviews. 206: 296-305. PMID 16048556 DOI: 10.1111/J.0105-2896.2005.00286.X |
0.409 |
|
| 2005 |
Targan SR, Landers CJ, Yang H, Lodes MJ, Cong Y, Papadakis KA, Vasiliauskas E, Elson CO, Hershberg RM. Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology. 128: 2020-8. PMID 15940634 DOI: 10.1053/J.Gastro.2005.03.046 |
0.396 |
|
| 2005 |
Hui T, Landers C, Vasiliauskas E, Abreu M, Dubinsky M, Papadakis KA, Price J, Lin YC, Huiying Y, Targan S, Fleshner P. Serologic responses in indeterminate colitis patients before ileal pouch-anal anastomosis may determine those at risk for continuous pouch inflammation. Diseases of the Colon and Rectum. 48: 1254-62. PMID 15868228 DOI: 10.1007/S10350-005-0013-0 |
0.415 |
|
| 2005 |
Papadakis KA, Zhu D, Prehn JL, Landers C, Avanesyan A, Lafkas G, Targan SR. Dominant role for TL1A/DR3 pathway in IL-12 plus IL-18-induced IFN-gamma production by peripheral blood and mucosal CCR9+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 4985-90. PMID 15814728 DOI: 10.4049/Jimmunol.174.8.4985 |
0.334 |
|
| 2005 |
Papadakis KA, Shaye OA, Vasiliauskas EA, Ippoliti A, Dubinsky MC, Birt J, Paavola J, Lee SK, Price J, Targan SR, Abreu MT. Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab. The American Journal of Gastroenterology. 100: 75-9. PMID 15654784 DOI: 10.1111/J.1572-0241.2005.40647.X |
0.34 |
|
| 2005 |
Cohavy O, Zhou J, Ware CF, Targan SR. LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling. Journal of Immunology (Baltimore, Md. : 1950). 174: 646-53. PMID 15634882 DOI: 10.4049/Jimmunol.174.2.646 |
0.354 |
|
| 2005 |
Sitaraman SV, Klapproth JM, Moore DA, Landers C, Targan S, Williams IR, Gewirtz AT. Elevated flagellin-specific immunoglobulins in Crohn's disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G403-6. PMID 15388489 DOI: 10.1152/Ajpgi.00357.2004 |
0.375 |
|
| 2005 |
Esrailian E, Targownik LE, Spiegel BM, Glassman P, Dubinsky MC, Targan SR, Gralnek IM. Is Endoscopic Ultrasound (EUS) Appropriate for the Diagnosis of Perianal Fistula in Crohn's Disease (CD)? A Survey of North American Inflammatory Bowel Disease (IBD) Experts Gastrointestinal Endoscopy. 61: AB275. DOI: 10.1016/S0016-5107(05)01425-2 |
0.418 |
|
| 2005 |
Karp LC, Targan SR. Ulcerative colitis: Evolving insights into pathogenesis Mucosal Immunology, Two-Volume Set. 1255-1263. DOI: 10.1016/B978-012491543-5/50075-9 |
0.319 |
|
| 2004 |
Papadakis KA, Prehn J, Zhu D, Landers C, Gaiennie J, Fleshner PR, Targan SR. Expression and regulation of the chemokine receptor CXCR3 on lymphocytes from normal and inflammatory bowel disease mucosa. Inflammatory Bowel Diseases. 10: 778-88. PMID 15626897 DOI: 10.1097/00054725-200411000-00013 |
0.391 |
|
| 2004 |
Arnott IDR, Landers CJ, Nimmo EJ, Drummond HE, Smith BKR, Targan SR, Satsangi J. Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype American Journal of Gastroenterology. 99: 2376-2384. PMID 15571586 DOI: 10.1111/J.1572-0241.2004.40417.X |
0.388 |
|
| 2004 |
Matuk R, Crawford J, Abreu MT, Targan SR, Vasiliauskas EA, Papadakis KA. The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease. Inflammatory Bowel Diseases. 10: 352-6. PMID 15475742 DOI: 10.1097/00054725-200407000-00005 |
0.429 |
|
| 2004 |
Youdim A, Vasiliauskas EA, Targan SR, Papadakis KA, Ippoliti A, Dubinsky MC, Lechago J, Paavola J, Loane J, Lee SK, Gaiennie J, Smith K, Do J, Abreu MT. A pilot study of adalimumab in infliximab-allergic patients. Inflammatory Bowel Diseases. 10: 333-8. PMID 15475739 DOI: 10.1097/00054725-200407000-00002 |
0.365 |
|
| 2004 |
Mow WS, Landers CJ, Steinhart AH, Feagan BG, Croitoru K, Seidman E, Greenberg GR, Targan SR. High-level serum antibodies to bacterial antigens are associated with antibiotic-induced clinical remission in Crohn's disease: a pilot study. Digestive Diseases and Sciences. 49: 1280-6. PMID 15387358 DOI: 10.1023/B:Ddas.0000037824.66186.E2 |
0.363 |
|
| 2004 |
Geller SA, Dubinsky MC, Poordad FF, Vasiliauskas EA, Cohen AH, Abreu MT, Tran T, Martin P, Vierling JM, Targan SR. Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease. The American Journal of Surgical Pathology. 28: 1204-11. PMID 15316320 DOI: 10.1097/01.Pas.0000128665.12063.97 |
0.395 |
|
| 2004 |
Papadakis KA, Matuk R, Abreu MT, Vasiliauskas EA, Fleshner PR, Lechago J, Tran T, Poordad FF, Martin P, Vierling J, Targan SR. Crohn's ileitis after liver transplantation from a living related donor with Crohn's disease. Gut. 53: 1389-90. PMID 15306609 DOI: 10.1136/Gut.2004.042523 |
0.32 |
|
| 2004 |
Cohavy O, Zhou J, Granger SW, Ware CF, Targan SR. LIGHT expression by mucosal T cells may regulate IFN-gamma expression in the intestine. Journal of Immunology (Baltimore, Md. : 1950). 173: 251-8. PMID 15210782 DOI: 10.4049/Jimmunol.173.1.251 |
0.333 |
|
| 2004 |
Prehn JL, Mehdizadeh S, Landers CJ, Luo X, Cha SC, Wei P, Targan SR. Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-γ, in mucosal inflammation Clinical Immunology. 112: 66-77. PMID 15207783 DOI: 10.1016/J.Clim.2004.02.007 |
0.383 |
|
| 2004 |
Papadakis KA, Prehn JL, Landers C, Han Q, Luo X, Cha SC, Wei P, Targan SR. TL1A synergizes with IL-12 and IL-18 to enhance IFN-gamma production in human T cells and NK cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 7002-7. PMID 15153521 DOI: 10.4049/Jimmunol.172.11.7002 |
0.302 |
|
| 2004 |
Lodes MJ, Cong Y, Elson CO, Mohamath R, Landers CJ, Targan SR, Fort M, Hershberg RM. Bacterial flagellin is a dominant antigen in Crohn disease. The Journal of Clinical Investigation. 113: 1296-306. PMID 15124021 DOI: 10.1172/Jci200420295 |
0.435 |
|
| 2004 |
Mow WS, Abreu-Martin MT, Papadakis KA, Pitchon HE, Targan SR, Vasiliauskas EA. High incidence of anergy in inflammatory bowel disease patients limits the usefulness of PPD screening before infliximab therapy. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 2: 309-13. PMID 15067625 DOI: 10.1016/S1542-3565(04)00060-6 |
0.333 |
|
| 2004 |
Mow WS, Lo SK, Targan SR, Dubinsky MC, Treyzon L, Abreu-Martin MT, Papadakis KA, Vasiliauskas EA. Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 2: 31-40. PMID 15017630 DOI: 10.1016/S1542-3565(03)00289-1 |
0.387 |
|
| 2004 |
Mow WS, Vasiliauskas EA, Lin YC, Fleshner PR, Papadakis KA, Taylor KD, Landers CJ, Abreu-Martin MT, Rotter JI, Yang H, Targan SR. Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease. Gastroenterology. 126: 414-24. PMID 14762777 DOI: 10.1053/J.Gastro.2003.11.015 |
0.387 |
|
| 2003 |
Papadakis KA, Treyzon L, Abreu MT, Fleshner PR, Targan SR, Vasiliauskas EA. Infliximab in the treatment of medically refractory indeterminate colitis. Alimentary Pharmacology & Therapeutics. 18: 741-747. PMID 14510748 DOI: 10.1046/J.1365-2036.2003.01739.X |
0.39 |
|
| 2003 |
Dubinsky MC, Vasiliauskas EA, Singh H, Abreu MT, Papadakis KA, Tran T, Martin P, Vierling JM, Geller SA, Targan SR, Poordad FF. 6-thioguanine can cause serious liver injury in inflammatory bowel disease patients. Gastroenterology. 125: 298-303. PMID 12891528 DOI: 10.1016/S0016-5085(03)00938-7 |
0.347 |
|
| 2003 |
Papadakis KA, Landers C, Prehn J, Kouroumalis EA, Moreno ST, Gutierrez-Ramos JC, Hodge MR, Targan SR. CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype and Th1 or T-regulatory 1 cytokine profile. Journal of Immunology (Baltimore, Md. : 1950). 171: 159-65. PMID 12816994 DOI: 10.4049/Jimmunol.171.1.159 |
0.359 |
|
| 2003 |
Dubinsky MC, Feldman EJ, Abreu MT, Targan SR, Vasiliauskas EA. Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. The American Journal of Gastroenterology. 98: 1058-63. PMID 12809828 DOI: 10.1111/J.1572-0241.2003.07413.X |
0.347 |
|
| 2003 |
Elson CO, Sartor RB, Targan SR, Sandborn WJ. Challenges in IBD Research: updating the scientific agendas. Inflammatory Bowel Diseases. 9: 137-53. PMID 12792219 DOI: 10.1097/00054725-200305000-00001 |
0.403 |
|
| 2003 |
Gonsky R, Deem RL, Young HA, Targan SR. CD2 mediates activation of the IFN-gamma intronic STAT binding region in mucosal T cells. European Journal of Immunology. 33: 1152-62. PMID 12731040 DOI: 10.1002/Eji.200322875 |
0.315 |
|
| 2003 |
Sugimura K, Taylor KD, Lin YC, Hang T, Wang D, Tang YM, Fischel-Ghodsian N, Targan SR, Rotter JI, Yang H. A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews. American Journal of Human Genetics. 72: 509-18. PMID 12577202 DOI: 10.1086/367848 |
0.366 |
|
| 2003 |
Papadakis KA, Rosenbloom B, Targan SR. Anti-CD2O chimeric monoclonal antibody (rituximab) treatment of immune-mediated thrombocytopenia associated with Crohn's disease. Gastroenterology. 124: 583. PMID 12557172 DOI: 10.1053/Gast.2003.50081 |
0.389 |
|
| 2003 |
Dubinsky MC, Lee-Uy N, Lin Y, Dutridge D, Vasiliauskas EA, Landers CJ, Targan SR, Roundtree B, Thomas D, Davis J, Dallalzadeh S, Bahar R, Taylor KD, Rotter JI, Yang H. Synergism of NOD2 and ASCA (Anti-saccharomyces cerevisiae antibodies) contributes to disease behavior in pediatric Crohn's disease (CD) patients Gastroenterology. 124: A372. DOI: 10.1016/S0016-5085(03)81883-8 |
0.408 |
|
| 2003 |
Arnott ID, Landers CJ, Targan SR, Satsangi J. Incidence and phenotypic associations of novel antibody markers in Crohn's disease Gastroenterology. 124: A196. DOI: 10.1016/S0016-5085(03)80982-4 |
0.383 |
|
| 2003 |
Cohavy O, Prehn J, Ware C, Targan SR. LIGHT is preferentially expressed on activated mucosal CD4+ and CD8+ T cells and augments CD2 mediated IFNγ production Gastroenterology. 124: A153. DOI: 10.1016/S0016-5085(03)80759-X |
0.301 |
|
| 2003 |
Plevy SE, Salzberg BA, Regueiro M, Sandborn W, Hanauer SB, Targan SR, Mayer L, Walters IB. A humanized anti-CD3 monoclonal antibody, visilizumab, for treatment of severe steroid-refractory ulcerative colitis: Preliminary results of a phase I study Gastroenterology. 124: A7. DOI: 10.1016/S0016-5085(03)80033-1 |
0.378 |
|
| 2003 |
Mow W, Vasiliauskas EA, Lin Y, Fleshner PR, Papadakis K, Taylor KD, Landers CJ, Rotter JI, Abreu MT, Yang H, Targan SR. Antibodies against the Crohn's disease (CD)-associated bacterial sequence 12 (anti-12) are an independent marker of fibrostenosing CD Gastroenterology. 124: A2. DOI: 10.1016/S0016-5085(03)80009-4 |
0.366 |
|
| 2002 |
Landers CJ, Cohavy O, Misra R, Yang H, Lin YC, Braun J, Targan SR. Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto- and microbial antigens. Gastroenterology. 123: 689-99. PMID 12198693 DOI: 10.1053/Gast.2002.35379 |
0.345 |
|
| 2002 |
Sandborn WJ, Targan SR. Biologic therapy of inflammatory bowel disease. Gastroenterology. 122: 1592-608. PMID 12016425 DOI: 10.1053/Gast.2002.33426 |
0.393 |
|
| 2002 |
Dubinsky MC, Yang H, Hassard PV, Seidman EG, Kam LY, Abreu MT, Targan SR, Vasiliauskas EA. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology. 122: 904-15. PMID 11910342 DOI: 10.1053/Gast.2002.32420 |
0.383 |
|
| 2002 |
Dubinsky MC, Hassard PV, Seidman EG, Kam LY, Abreu MT, Targan SR, Vasiliauskas EA. An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy. Inflammatory Bowel Diseases. 7: 181-9. PMID 11515842 DOI: 10.1097/00054725-200108000-00001 |
0.408 |
|
| 2001 |
Prehn JL, Landers C, Muller GW, Man HW, Stirling DI, Targan SR. Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues. Journal of Clinical Immunology. 21: 357-64. PMID 11720008 DOI: 10.1023/A:1012292703871 |
0.37 |
|
| 2001 |
Wei B, Dalwadi H, Gordon LK, Landers C, Bruckner D, Targan SR, Braun J. Molecular cloning of a Bacteroides caccae TonB-linked outer membrane protein identified by an inflammatory bowel disease marker antibody. Infection and Immunity. 69: 6044-54. PMID 11553542 DOI: 10.1128/Iai.69.10.6044-6054.2001 |
0.377 |
|
| 2001 |
Sandborn WJ, Loftus EV, Colombel JF, Fleming KA, Seibold F, Homburger HA, Sendid B, Chapman RW, Tremaine WJ, Kaul DK, Wallace J, Harmsen WS, Zinsmeister AR, Targan SR. Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease. Inflammatory Bowel Diseases. 7: 192-201. PMID 11515844 DOI: 10.1097/00054725-200108000-00003 |
0.397 |
|
| 2001 |
Papadakis KA, Prehn J, Moreno ST, Cheng L, Kouroumalis EA, Deem R, Breaverman T, Ponath PD, Andrew DP, Green PH, Hodge MR, Binder SW, Targan SR. CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease. Gastroenterology. 121: 246-54. PMID 11487533 DOI: 10.1053/Gast.2001.27154 |
0.4 |
|
| 2001 |
Taylor KD, Plevy SE, Yang H, Landers CJ, Barry MJ, Rotter JI, Targan SR. ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease Gastroenterology. 120: 1347-1355. PMID 11313304 DOI: 10.1053/Gast.2001.23966 |
0.379 |
|
| 2001 |
Sandborn WJ, Feagan BG, Hanauer SB, Present DH, Sutherland LR, Kamm MA, Wolf DC, Baker JP, Hawkey C, Archambault A, Bernstein CN, Novak C, Heath PK, Targan SR. An engineered human antibody to TNF (CDP571) for active Crohn's disease: a randomized double-blind placebo-controlled trial. Gastroenterology. 120: 1330-8. PMID 11313302 DOI: 10.1053/Gast.2001.24042 |
0.343 |
|
| 2001 |
Cornillie F, Shealy D, D'Haens G, Geboes K, Van Assche G, Ceuppens J, Wagner C, Schaible T, Plevy SE, Targan SR, Rutgeerts P. Infliximab induces potent anti-inflammatory and local immunomodulatory activity but no systemic immune suppression in patients with Crohn's disease Alimentary Pharmacology and Therapeutics. 15: 463-473. PMID 11284774 DOI: 10.1046/J.1365-2036.2001.00956.X |
0.308 |
|
| 2001 |
Dubinsky MC, Ofman JJ, Urman M, Targan SR, Seidman EG. Clinical utility of serodiagnostic testing in suspected pediatric inflammatory bowel disease. The American Journal of Gastroenterology. 96: 758-65. PMID 11280547 DOI: 10.1016/S0002-9270(00)02411-4 |
0.379 |
|
| 2001 |
Kam LY, Targan SR. TNF-alpha antagonists for the treatment of Crohn's disease. Expert Opinion On Pharmacotherapy. 1: 615-22. PMID 11249506 DOI: 10.1517/14656566.1.4.615 |
0.303 |
|
| 2001 |
Pimentel M, Chang M, Chow EJ, Tabibzadeh S, Kirit-Kiriak V, Targan SR, Lin HC. Identification of a prodromal period in Crohn's disease but not ulcerative colitis. The American Journal of Gastroenterology. 95: 3458-62. PMID 11151877 DOI: 10.1111/J.1572-0241.2000.03361.X |
0.403 |
|
| 2001 |
Papadakis KA, Targan SR. The role of chemokines and chemokine receptors in mucosal inflammation. Inflammatory Bowel Diseases. 6: 303-13. PMID 11149563 DOI: 10.1002/Ibd.3780060408 |
0.334 |
|
| 2001 |
Landers CJ, Cohavy O, Yang H, Lin S, Braun J, Targan SR. Selected, not global, loss of tolerance using Crohn's disease (CD)-associated immune responses to auto-and specific bacterial antigens Gastroenterology. 120: A521-A522. DOI: 10.1016/S0016-5085(08)82590-5 |
0.375 |
|
| 2001 |
Wei B, Dalwadi HN, Gordon LK, Landers CJ, Targan SR, Braun J. Molecular cloning of a Bacteroides caccae TonB-linked outer membrane protein identified by a inflammatory bowel disease marker antibody Gastroenterology. 120: A519. DOI: 10.1016/S0016-5085(08)82577-2 |
0.356 |
|
| 2001 |
Gonsky R, Deem RL, Young HA, Targan SR. Dampened SOCS: An altered balance between STAT activating and SOCS inhibitory signals regulate interferon-γ expression in LPMC Gastroenterology. 120: A38. DOI: 10.1016/S0016-5085(08)80184-9 |
0.312 |
|
| 2000 |
Papadakis KA, Prehn J, Nelson V, Cheng L, Binder SW, Ponath PD, Andrew DP, Targan SR. The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. Journal of Immunology (Baltimore, Md. : 1950). 165: 5069-76. PMID 11046037 DOI: 10.4049/Jimmunol.165.9.5069 |
0.398 |
|
| 2000 |
Papadakis KA, Targan SR. Tumor necrosis factor: biology and therapeutic inhibitors. Gastroenterology. 119: 1148-57. PMID 11040201 DOI: 10.1053/Gast.2000.18160 |
0.332 |
|
| 2000 |
Targan SR. Biology of inflammation in Crohn's disease: mechanisms of action of anti-TNF-a therapy. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 13C-16C. PMID 11023555 DOI: 10.1155/2000/409396 |
0.408 |
|
| 2000 |
Papadakis KA, Targan SR. Serologic testing in inflammatory bowel disease: its value in indeterminate colitis. Current Gastroenterology Reports. 1: 482-5. PMID 10980990 DOI: 10.1007/S11894-999-0007-5 |
0.444 |
|
| 2000 |
Sutton CL, Kim J, Yamane A, Dalwadi H, Wei B, Landers C, Targan SR, Braun J. Identification of a novel bacterial sequence associated with Crohn's disease. Gastroenterology. 119: 23-31. PMID 10889151 DOI: 10.1053/Gast.2000.8519 |
0.379 |
|
| 2000 |
Papadakis KA, Targan SR. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annual Review of Medicine. 51: 289-98. PMID 10774465 DOI: 10.1146/Annurev.Med.51.1.289 |
0.44 |
|
| 2000 |
Dubinsky MC, Lamothe S, Yang HY, Targan SR, Sinnett D, Théorêt Y, Seidman EG. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology. 118: 705-13. PMID 10734022 DOI: 10.1016/S0016-5085(00)70140-5 |
0.333 |
|
| 2000 |
Trachtenberg EA, Yang H, Hayes E, Vinson M, Lin C, Targan SR, Tyan D, Erlich H, Rotter JI. HLA Class II Haplotype Associations with Inflammatory Bowel Disease in Jewish (Ashkenazi) and Non-Jewish Caucasian Populations Human Immunology. 61: 326-333. PMID 10689124 DOI: 10.1016/S0198-8859(99)00134-2 |
0.39 |
|
| 2000 |
Cohavy O, Bruckner D, Gordon LK, Misra R, Wei B, Eggena ME, Targan SR, Braun J. Colonic bacteria express an ulcerative colitis pANCA-related protein epitope. Infection and Immunity. 68: 1542-8. PMID 10678972 DOI: 10.1128/Iai.68.3.1542-1548.2000 |
0.366 |
|
| 2000 |
Eggena M, Cohavy O, Parseghian MH, Hamkalo BA, Clemens D, Targan SR, Gordon LK, Braun J. Identification of histone H1 as a cognate antigen of the ulcerative colitis-associated marker antibody pANCA. Journal of Autoimmunity. 14: 83-97. PMID 10648119 DOI: 10.1006/Jaut.1999.0340 |
0.322 |
|
| 2000 |
Gonsky R, Deem RL, Bream JH, Lee DH, Young HA, Targan SR. Mucosa-specific targets for regulation of IFN-gamma expression: lamina propria T cells use different cis-elements than peripheral blood T cells to regulate transactivation of IFN-gamma expression. Journal of Immunology (Baltimore, Md. : 1950). 164: 1399-407. PMID 10640755 DOI: 10.4049/Jimmunol.164.3.1399 |
0.305 |
|
| 2000 |
Gordon LK, Eggena M, Targan SR, Braun J. Mast cell and neuroendocrine cytoplasmic autoantigen(s) detected by monoclonal pANCA antibodies. Clinical Immunology (Orlando, Fla.). 94: 42-50. PMID 10607489 DOI: 10.1006/Clim.1999.4805 |
0.364 |
|
| 2000 |
Dubinsky MC, Hassard PV, Abreu MT, Kam LY, Seidman EG, Targan SR, Vasiliauskas EA. Thioguanine (6-TG): A therapeutic alternative in a subgroup of IBD patients failing 6-mercaptopurine (6-MP) Gastroenterology. 118: A891. DOI: 10.1016/S0016-5085(00)85701-7 |
0.326 |
|
| 2000 |
Taylor KD, Vasiliauskas EA, Kam LY, Lin Y, Targan SR, Rotter JI, Yang H. Specific clinical and immunological features in Crohn's disease patients are associated with the MCH class III marker Notch4 Gastroenterology. 118: A869. DOI: 10.1016/S0016-5085(00)85616-4 |
0.36 |
|
| 2000 |
Papadakis KA, Prehn JL, Andrew DP, Ponath PD, Targan SR. Regional expression of thymus expressed chemokine (TECK) and its receptor ccr9 in the small bowel: Evidence for enhanced recirculation of CCR9+ lymphocytes in small bowel crohn's disease Gastroenterology. 118: A663. DOI: 10.1016/S0016-5085(00)84788-5 |
0.374 |
|
| 2000 |
Sanborn WJ, Targan SR, Hanauer SB, Present DH, Sutherland LR, Kamm MA, Wolf DC, Baker J, Hawkey CJ, Heath PK, Feagan BG. A randomized controlled trial of CDP571, a humanized antibody to TNFA, in moderately to severely active Crohn's disease Gastroenterology. 118: A655. DOI: 10.1016/S0016-5085(00)84760-5 |
0.329 |
|
| 2000 |
Kam LY, Vasiliauskas EA, Abreu MT, Hassard PV, Kalenich A, Gaiennie J, Record L, Schaible TF, Targan SR. Attenuation of response to multiple retreatment infliximab infusions for active Crohn's disease (CD): potential factors that minimize decreased response Gastroenterology. 118: A655. DOI: 10.1016/S0016-5085(00)84759-9 |
0.364 |
|
| 2000 |
Papadakis KA, Prehn JL, Targan SR. Alterations in expression and regulation of the chemokine receptor CXCR3 in LPL from normal compared to inflammatory bowel disease mucosa Gastroenterology. 118: A350. DOI: 10.1016/S0016-5085(00)83503-9 |
0.379 |
|
| 2000 |
Landers CJ, Yang H, Lin Y, Vasiliauskas EA, Braun J, Targan SR. IGA serum antibody reactivity with I2, a novel Crohn's disease marker: anti-I2 level is independent from ASCA and ANCA levels, even though IGA ASCA positivity is correlated with anti-I2 positivity Gastroenterology. 118: A348. DOI: 10.1016/S0016-5085(00)83491-5 |
0.322 |
|
| 2000 |
Landers CJ, Braun J, Targan SR. I2,A mucosal Crohn's disease (CD)associated bacterial antigen, induces both humoral and T-cell responses in CD patients: I2 induced interferon-Γ (IFN-Γ) production is associated with higher levels of serum IGA reactivity Gastroenterology. 118: A347. DOI: 10.1016/S0016-5085(00)83490-3 |
0.384 |
|
| 2000 |
Yang H, Taylor KD, Lin Y, Targan SR, Rotter JI. Magnitude of anti-saccharomyces cerevisiae antibody (ASCA) expression is linked, in crohn's disease, families to the major histocompatibility complex (MHC) region Gastroenterology. 118: A339. DOI: 10.1016/S0016-5085(00)83453-8 |
0.338 |
|
| 2000 |
Taylor KD, Yang H, Lin Y, Vasiliauskas EA, Targan SR, Rotter JI. Chronic pouchitis after ileal pouch-anal anastomosis for ulcerative colitis (UC) is associated with the interferon-Γ receptor-A (IFNΓRA) gene independent of perinuclear antineutrophil cytoplasmic antibody (pANCA) level Gastroenterology. 118: A338. DOI: 10.1016/S0016-5085(00)83447-2 |
0.312 |
|
| 2000 |
Sandborn WJ, Loftus EV, Colombel JF, Fleming K, Seibold F, Homburger HA, Sendid B, Chapman RW, Tremaine WJ, Kaul DK, Harmsen WS, Targan SR. Utility of perinuclear anti-neutrophil cytoplasmic antibodies (pANCA), anti-saccharomyces cerevisiae (ASCA), and anti-pancreatic antibodies (APA) as serologic markers in a population based cohort of patients with Crohn's disease (CD) and ulcerative colitis (UC) Gastroenterology. 118: A106. DOI: 10.1016/S0016-5085(00)82501-9 |
0.382 |
|
| 2000 |
Sandborn WJ, Targan SR, Hanauer SB, Present DH, Sutherland LR, Kamm M, Wolf D, Baker J, Hawkey C, Heath PK, Feagan BG. A six-month open label evaluation of CDP571, a humanized antibody to TNFa, in active Crohn's disease Gastroenterology. 118: A1367. DOI: 10.1016/S0016-5085(00)81342-6 |
0.332 |
|
| 2000 |
Pimentel M, Chang M, Chow EJ, Tabibzadeh S, Kirit-Kiriak V, Targan SR, Lin HC. Original contributionIdentification of a prodromal period in Crohn’s disease but not ulcerative colitis The American Journal of Gastroenterology. 95. DOI: 10.1016/S0002-9270(00)02154-7 |
0.379 |
|
| 1999 |
Kam LY, Targan SR. Cytokine-based therapies in inflammatory bowel disease. Current Opinion in Gastroenterology. 15: 302-307. PMID 17023962 DOI: 10.1097/00001574-199907000-00005 |
0.374 |
|
| 1999 |
Vasiliauskas EA, Kam LY, Abreu-Martin MT, Hassard PV, Papadakis KA, Yang H, Zeldis JB, Targan SR. An open-label pilot study of low-dose thalidomide in chronically active, steroid-dependent Crohn's disease. Gastroenterology. 117: 1278-1287. PMID 10579968 DOI: 10.1016/S0016-5085(99)70277-5 |
0.366 |
|
| 1999 |
Sandborn WJ, Tremaine WJ, Wolf DC, Targan SR, Sninsky CA, Sutherland LR, Hanauer SB, McDonald JWD, Feagan BG, Fedorak RN, Isaacs KL, Pike MG, Mays DC, Lipsky JJ, Gordon S, et al. Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease Gastroenterology. 117: 527-535. PMID 10464128 DOI: 10.1016/S0016-5085(99)70445-2 |
0.336 |
|
| 1999 |
Papadakis KA, Targan SR. Current theories on the causes of inflammatory bowel disease. Gastroenterology Clinics of North America. 28: 283-96. PMID 10372269 DOI: 10.1016/S0889-8553(05)70057-1 |
0.421 |
|
| 1999 |
Facklis K, Plevy SE, Vasiliauskas EA, Kam L, Taylor K, Targan SR, Fleshner PR. Crohn's disease-associated genetic marker is seen in medically unresponsive ulcerative colitis patients and may be associated with pouch- specific complications Diseases of the Colon and Rectum. 42: 601-606. PMID 10344681 DOI: 10.1007/Bf02234133 |
0.383 |
|
| 1999 |
Yang H, Plevy SE, Taylor K, Tyan D, Fischel-Ghodsian N, McElree C, Targan SR, Rotter JI. Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses Gut. 44: 519-526. PMID 10075959 DOI: 10.1136/Gut.44.4.519 |
0.344 |
|
| 1999 |
Targan SR. The utility of ANCA and ASCA in inflammatory bowel disease. Inflammatory Bowel Diseases. 5: 61-3; discussion 66-. PMID 10028450 DOI: 10.1097/00054725-199902000-00008 |
0.414 |
|
| 1999 |
Cohavy O, Harth G, Horwitz M, Eggena M, Landers C, Sutton C, Targan SR, Braun J. Identification of a Novel Mycobacterial Histone H1 Homologue (HupB) as an Antigenic Target of pANCA Monoclonal Antibody and Serum Immunoglobulin A from Patients with Crohn's Disease Infection and Immunity. 67: 6510-6517. DOI: 10.1128/Iai.67.12.6510-6517.1999 |
0.353 |
|
| 1999 |
Vasiliauskas EA, Thomas DW, Schaffer S, Dezenberg C, Noel J, Marshall WF, Targan SR. COLLABORATIVE EXPERIENCE OF OPEN-LABEL INFLIXIMAB IN REFRACTORY PEDIATRIC CROHN'S DISEASE Journal of Pediatric Gastroenterology & Nutrition. 29: 525. DOI: 10.1097/00005176-199910000-00170 |
0.328 |
|
| 1998 |
Ruemmele FM, Targan SR, Levy G, Dubinsky M, Braun J, Seidman EG. Diagnostic accuracy of serological assays in pediatric inflammatory bowel disease. Gastroenterology. 115: 822-9. PMID 9753483 DOI: 10.1016/S0016-5085(98)70252-5 |
0.424 |
|
| 1998 |
Quinton JF, Sendid B, Reumaux D, Duthilleul P, Cortot A, Grandbastien B, Charrier G, Targan SR, Colombel JF, Poulain D. Anti-Saccharomyces cerevisiae manna antibodies combined with antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease: Prevalence and diagnostic role Gut. 42: 788-791. PMID 9691915 DOI: 10.1136/Gut.42.6.788 |
0.4 |
|
| 1998 |
Targan SR. The search for pathogenic antigens in ulcerative colitis. Gastroenterology. 114: 1099-100. PMID 9606095 DOI: 10.1016/S0016-5085(98)70331-2 |
0.307 |
|
| 1998 |
Satsangi J, Landers CJ, Welsh KI, Koss K, Targan S, Jewell DP. The presence of anti‐neutrophil antibodies reflects clinical and genetic heterogeneity within inflammatory bowel disease Inflammatory Bowel Diseases. 4: 18-26. PMID 9552224 DOI: 10.1097/00054725-199802000-00004 |
0.445 |
|
| 1998 |
Kaditis AG, Perrault J, Sandborn WJ, Landers CJ, Zinsmeister AR, Targan SR. Antineutrophil cytoplasmic antibody subtypes in children and adolescents after ileal pouch-anal anastomosis for ulcerative colitis. Journal of Pediatric Gastroenterology and Nutrition. 26: 386-92. PMID 9552133 DOI: 10.1097/00005176-199804000-00005 |
0.334 |
|
| 1998 |
Vasiliauskas EA, Kam L, Gaiennie J, Targan SR. EARLY ONSET CROHN'S DISEASE (CD) DIFFERS FROM LATE ADULT ONSET CD - IMMUNOLOGIC EVIDENCE Journal of Pediatric Gastroenterology & Nutrition. 27: 471. DOI: 10.1097/00005176-199810000-00053 |
0.332 |
|
| 1998 |
Yang H, Ohmen J, Ma R, Li Z, Bentley L, Targan S, Fischerl-Ghodsian N, Rotter J. Linkage and association between Crohn's disease and a putative locus on chromosome 12 Gastroenterology. 114: A1119. DOI: 10.1016/S0016-5085(98)84551-4 |
0.328 |
|
| 1998 |
Lee DH, Gonsky R, Deem RL, Targan SR. A unique mode of CD28 augmentation of IL-2 expression in lamina propria T-cells: mRNA stabilization without transactivation of the CD28 response element (CD28RE) Gastroenterology. 114: A1019. DOI: 10.1016/S0016-5085(98)84145-0 |
0.319 |
|
| 1998 |
Gonsky R, Deem RL, Young HA, Targan SR. Identification of both Cd2 enhancer and repressor elements within the interferon-λ promoter which regulate cytokine secretion in lamina propria T-cells Gastroenterology. 114: A986-A987. DOI: 10.1016/S0016-5085(98)84017-1 |
0.31 |
|
| 1997 |
Targan SR, Hanauer SB, Deventer SJHv, Mayer L, Present DH, Braakman T, DeWoody KL, Schaible TF, Rutgeerts PJ. A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease The New England Journal of Medicine. 337: 1029-1035. PMID 9321530 DOI: 10.1056/Nejm199710093371502 |
0.337 |
|
| 1997 |
Roussomoustakaki M, Satsangi J, Welsh K, Louis E, Fanning G, Targan S, Landers C, Jewell DP. Genetic markers may predict disease behavior in patients with ulcerative colitis. Gastroenterology. 112: 1845-1853. PMID 9178675 DOI: 10.1053/Gast.1997.V112.Pm9178675 |
0.342 |
|
| 1996 |
Vasiliauskas EA, Plevy SE, Landers CJ, Binder SW, Ferguson DM, Yang H, Rotter JI, Vidrich A, Targan SR. Perinuclear antineutrophil cytoplasmic antibodies in patients with Crohn's disease define a clinical subgroup. Gastroenterology. 110: 1810-9. PMID 8964407 DOI: 10.1053/Gast.1996.V110.Pm8964407 |
0.395 |
|
| 1996 |
Abreu-Martin MT, Targan SR. Regulation Of Immune Responses Of The Intestinal Mucosa Critical Reviews in Immunology. 16: 277-309. PMID 8922900 DOI: 10.1615/Critrevimmunol.V16.I3.30 |
0.343 |
|
| 1996 |
Ohmen JD, Yang H, Yamamoto KK, Zhao H, Ma Y, Bentley LG, Huang Z, Gerwehr S, Pressman S, McElree C, Targan S, Rotter JI, Fischel-Ghodsian N. Susceptibility Locus for Inflammatory Bowel Disease on Chromosome 16 has a Role in Crohn's disease, but Not in Ulcerative Colitis Human Molecular Genetics. 5: 1679-1683. PMID 8894707 DOI: 10.1093/Hmg/5.10.1679 |
0.415 |
|
| 1996 |
Plevy SE, Targan SR, Yang H, Fernandez D, Rotter JI, Toyoda H. Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6 Gastroenterology. 110: 1053-1060. PMID 8612993 DOI: 10.1053/Gast.1996.V110.Pm8612993 |
0.379 |
|
| 1996 |
Vidrich A, Lee J, James E, Cobb L, Targan S. Segregation of pANCA antigenic recognition by DNase treatment of neutrophils: ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis. Journal of Clinical Immunology. 15: 293-9. PMID 8576315 DOI: 10.1007/Bf01541319 |
0.379 |
|
| 1996 |
Targan SR, Murphy LK. Clarifying the causes of Crohn's. Nature Medicine. 1: 1241-3. PMID 7489397 DOI: 10.1038/Nm1295-1241 |
0.365 |
|
| 1996 |
Plevy SE, Targan SR. ANTI-TUMOR NECROSIS FACTOR-α THERAPY IN CROHN'S DISEASE: A MAGIC BULLET FINALLY HITS ITS MARK. Inflammatory Bowel Diseases. 2: 158-159. DOI: 10.1002/Ibd.3780020216 |
0.324 |
|
| 1995 |
Yang H, Vora DK, Targan SR, Toyoda H, Beaudet AL, Rotter JI. Intercellular adhesion molecule 1 gene associations with immunologic subsets of inflammatory bowel disease. Gastroenterology. 109: 440-8. PMID 7615193 DOI: 10.1016/0016-5085(95)90331-3 |
0.446 |
|
| 1995 |
Fleshner PR, Michelassi F, Rubin M, Hanauer SB, Plevy SE, Targan SR. Morbidity of subtotal colectomy in patients with severe ulcerative colitis unresponsive to cyclosporin Diseases of the Colon &Amp; Rectum. 38: 1241-1245. PMID 7497833 DOI: 10.1007/Bf02049146 |
0.333 |
|
| 1995 |
Kim WH, Choi PM, Landers CJ, Targan SR. Role of antineutrophil cytoplasmic antibodies in an ethnically distinct population: Korean patients with ulcerative colitis. The American Journal of Gastroenterology. 90: 1953-1958. DOI: 10.1111/J.1572-0241.1995.Tb10169.X |
0.339 |
|
| 1995 |
Targan SR, Landers CJ, MacDermott RP, Vidrich A. Gut mucosa is the site of antigenic B-cell priming and production of perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) in patients with ulcerative colitis (UC) Gastroenterology. 108: A926. DOI: 10.1016/0016-5085(95)28011-1 |
0.324 |
|
| 1995 |
Targan SR. New IBD markers: definition of disease heterogeneity Canadian Journal of Gastroenterology & Hepatology. 9: 301-304. DOI: 10.1007/978-94-009-0371-5_22 |
0.41 |
|
| 1994 |
Choi PM, Targan SR. Immunomodulator therapy in inflammatory bowel disease. Digestive Diseases and Sciences. 39: 1885-92. PMID 7521821 DOI: 10.1007/Bf02088121 |
0.388 |
|
| 1994 |
Winter HS, Landers CJ, Winkelstein A, Vidrich A, Targan SR. Anti-neutrophil cytoplasmic antibodies in children with ulcerative colitis The Journal of Pediatrics. 125: 707-711. DOI: 10.1016/S0022-3476(06)80166-6 |
0.389 |
|
| 1994 |
Castro R, Yang H, Apple R, Targan S, Erlich H, Rotter J. Inflammatory bowel disease associations with HLA-class II genes Human Immunology. 40: 95. DOI: 10.1016/0198-8859(94)91847-3 |
0.35 |
|
| 1993 |
Treem WR, Veligati LN, Rotter JI, Targan SR, Hyams JS. Ulcerative colitis and total alopecia in a mother and her son. Gastroenterology. 104: 1187-91. PMID 8462807 DOI: 10.1016/0016-5085(93)90291-J |
0.362 |
|
| 1993 |
Toyoda H, Wang SJ, Yang HY, Redford A, Magalong D, Tyan D, McElree CK, Pressman SR, Shanahan F, Targan SR. Distinct associations of HLA class II genes with inflammatory bowel disease. Gastroenterology. 104: 741-8. PMID 8440433 DOI: 10.1016/0016-5085(93)91009-7 |
0.371 |
|
| 1993 |
Yang H, Rotter JI, Toyoda H, Landers C, Tyran D, McElree CK, Targan SR. Ulcerative colitis: a genetically heterogeneous disorder defined by genetic (HLA class II) and subclinical (antineutrophil cytoplasmic antibodies) markers. Journal of Clinical Investigation. 92: 1080-1084. PMID 8349790 DOI: 10.1172/Jci116613 |
0.352 |
|
| 1992 |
Shanahan F, Landers C, Duerr R, Targan SR. Neutrophil autoantibodies as disease markers for ulcerative colitis. Immunologic Research. 10: 479-84. PMID 1955775 DOI: 10.1007/Bf02919745 |
0.404 |
|
| 1992 |
Targan SR, Deem RL, Shanahan F. Role of mucosal T-cell-generated cytokines in epithelial cell injury. Immunologic Research. 10: 472-8. PMID 1955774 DOI: 10.1007/Bf02919744 |
0.353 |
|
| 1992 |
Shanahan F, Duerr RH, Rotter JI, Yang H, Sutherland LR, McElree C, Landers CJ, Targan SR. Neutrophil autoantibodies in ulcerative colitis: familial aggregation and genetic heterogeneity. Gastroenterology. 103: 456-461. PMID 1634063 DOI: 10.1016/0016-5085(92)90834-L |
0.328 |
|
| 1992 |
Shanahan F, Targan S. Medical Treatment of Inflammatory Bowel Disease Annual Review of Medicine. 43: 125-133. DOI: 10.1146/Annurev.Me.43.020192.001013 |
0.378 |
|
| 1991 |
Duerr RH, Targan SR, Landers CJ, Sutherland LR, Shanahan F. Anti-neutrophil cytoplasmic antibodies in ulcerative colitis. Comparison with other colitides/diarrheal illnesses. Gastroenterology. 100: 1590-6. PMID 2019365 DOI: 10.1016/0016-5085(91)90657-7 |
0.371 |
|
| 1990 |
Saxon A, Shanahan F, Landers C, Ganz T, Targan S. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease The Journal of Allergy and Clinical Immunology. 86: 202-210. PMID 2200820 DOI: 10.1016/S0091-6749(05)80067-3 |
0.447 |
|
| 1990 |
Targan SR, Deem RL, Shanahan F. Immune-Mediated Cytotoxicity in Inflammatory Bowel Disease Canadian Journal of Gastroenterology. 4: 278-284. DOI: 10.1155/1990/310128 |
0.413 |
|
| 1989 |
Randolph LM, Toyoda H, McElree CK, Shanahan F, Targan SR, Rotter JI. Lack of an association between polymorphisms of the T-cell receptor alpha-chain and ulcerative colitis. Gastroenterology. 97: 1115-20. PMID 2571544 DOI: 10.1016/0016-5085(89)91680-6 |
0.373 |
|
| 1989 |
Anton PA, Targan SR, Shanahan F. Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease. Gastroenterology. 97: 20-8. PMID 2542118 DOI: 10.1016/0016-5085(89)91410-8 |
0.434 |
|
| 1989 |
Shanahan F, Leman B, Deem R, Niederlehner A, Brogan M, Targan S. Enhanced peripheral blood T-cell cytotoxicity in inflammatory bowel disease. Journal of Clinical Immunology. 9: 55-64. PMID 2522935 DOI: 10.1007/Bf00917128 |
0.42 |
|
| 1988 |
Anton PA, Targan SR, Vigna SR, Durham M, Schwabe AD, Shanahan F. Enhanced neutrophil chemiluminescence in familial Mediterranean fever. Journal of Clinical Immunology. 8: 148-56. PMID 3372691 DOI: 10.1007/Bf00917903 |
0.345 |
|
| 1988 |
Karp LC, Targan SR. New enema treatments for inflammatory bowel disease. Digestive Diseases and Sciences. 33: 85S-87S. PMID 3278870 DOI: 10.1007/Bf01538136 |
0.333 |
|
| 1988 |
Deem RL, Shanahan F, Niederlehner A, Targan SR. Role of the CD45 (T-200) molecule in anti-CD3-triggered T cell-mediated cytotoxicity. Cellular Immunology. 117: 99-110. PMID 2972397 DOI: 10.1016/0008-8749(88)90080-9 |
0.327 |
|
| 1988 |
Shanahan F, Deem R, Nayersina R, Leman B, Targan S. Human mucosal T-cell cytotoxicity. Gastroenterology. 94: 960-7. PMID 2450050 DOI: 10.1016/0016-5085(88)90554-9 |
0.353 |
|
| 1987 |
Targan SR, Kagnoff MF, Brogan MD, Shanahan F. Immunologic mechanisms in intestinal diseases. Annals of Internal Medicine. 106: 853-70. PMID 3555203 DOI: 10.7326/0003-4819-106-6-853 |
0.389 |
|
| 1987 |
Shanahan F, Brogan M, Targan S. Human mucosal cytotoxic effector cells Gastroenterology. 92: 1951-1957. DOI: 10.1016/0016-5085(87)90629-9 |
0.33 |
|
| 1986 |
Elson CO, Kagnoff MF, Fiocchi C, Befus AD, Targan S. Intestinal immunity and inflammation: recent progress. Gastroenterology. 91: 746-68. PMID 3089867 DOI: 10.1016/0016-5085(86)90649-9 |
0.386 |
|
| 1985 |
Brogan M, Hiserodt J, Oliver M, Stevens R, Korelitz B, Targan S. The effect of 6-mercaptopurine on natural killer-cell activities in Crohn's disease. Journal of Clinical Immunology. 5: 204-11. PMID 3874211 DOI: 10.1007/Bf00915512 |
0.39 |
|
| 1985 |
Stevens R, Oliver M, Brogan M, Heiserodt J, Targan S. Defective generation of tetanus-specific antibody-producing B cells after in vivo immunization of Crohn's disease and ulcerative colitis patients. Gastroenterology. 88: 1860-1866. PMID 3873371 DOI: 10.1016/0016-5085(85)90011-3 |
0.392 |
|
| 1982 |
Schwartz AG, Targan SR, Saxon A, Weinstein WM. Sulfasalazine-induced exacerbation of ulcerative colitis New England Journal of Medicine. 306: 409-412. PMID 6120459 DOI: 10.1056/Nejm198202183060708 |
0.345 |
|
| 1976 |
Targan SR, Chow AW, Gun LB. Spontaneous Peritonitis of Cirrhosis Due to Camipylobacter Fetus Gastroenterology. 71: 311-313. DOI: 10.1016/S0016-5085(76)80210-7 |
0.309 |
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