☰

cached image

Shankar Balasubramanian, Ph.D. - Publications

Affiliations: 
1994- Chemistry University of Cambridge, Cambridge, England, United Kingdom 
Area:
DNA, quadruplexes, sequencing
Website:
http://www.ch.cam.ac.uk/group/shankar
Tree Info Similar researchers PubMed Report error

241 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Serrano-Benitez A, Wells SE, Drummond-Clarke L, Russo LC, Thomas JC, Leal GA, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, et al. Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity. The Embo Journal. e113190. PMID 37492888 DOI: 10.15252/embj.2022113190  0.592
2023 Füllgrabe J, Gosal WS, Creed P, Liu S, Lumby CK, Morley DJ, Ost TWB, Vilella AJ, Yu S, Bignell H, Burns P, Charlesworth T, Fu B, Fordham H, Harding NJ, ... ... Balasubramanian S, et al. Simultaneous sequencing of genetic and epigenetic bases in DNA. Nature Biotechnology. PMID 36747096 DOI: 10.1038/s41587-022-01652-0  0.306
2022 Galli S, Melidis L, Flynn SM, Varshney D, Simeone A, Spiegel J, Madden SK, Tannahill D, Balasubramanian S. DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody. Journal of the American Chemical Society. PMID 36488193 DOI: 10.1021/jacs.2c10656  0.733
2022 Hui WWI, Simeone A, Zyner KG, Tannahill D, Balasubramanian S. Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells. Scientific Reports. 12: 908. PMID 35022562 DOI: 10.1038/s41598-022-05047-8  0.825
2022 Zyner KG, Simeone A, Flynn SM, Doyle C, Marsico G, Adhikari S, Portella G, Tannahill D, Balasubramanian S. G-quadruplex DNA structures in human stem cells and differentiation. Nature Communications. 13: 142. PMID 35013231 DOI: 10.1038/s41467-021-27719-1  0.835
2021 Hui WWI, Simeone A, Zyner KG, Tannahill D, Balasubramanian S. Single-cell mapping of DNA G-quadruplex structures in human cancer cells. Scientific Reports. 11: 23641. PMID 34880271 DOI: 10.1038/s41598-021-02943-3  0.841
2021 Varshney D, Cuesta SM, Herdy B, Abdullah UB, Tannahill D, Balasubramanian S. RNA G-quadruplex structures control ribosomal protein production. Scientific Reports. 11: 22735. PMID 34815422 DOI: 10.1038/s41598-021-01847-6  0.832
2021 Zhang X, Spiegel J, Martínez Cuesta S, Adhikari S, Balasubramanian S. Chemical profiling of DNA G-quadruplex-interacting proteins in live cells. Nature Chemistry. 13: 626-633. PMID 34183817 DOI: 10.1038/s41557-021-00736-9  0.378
2021 Shen J, Varshney D, Simeone A, Zhang X, Adhikari S, Tannahill D, Balasubramanian S. Promoter G-quadruplex folding precedes transcription and is controlled by chromatin. Genome Biology. 22: 143. PMID 33962653 DOI: 10.1186/s13059-021-02346-7  0.723
2021 Spiegel J, Cuesta SM, Adhikari S, Hänsel-Hertsch R, Tannahill D, Balasubramanian S. G-quadruplexes are transcription factor binding hubs in human chromatin. Genome Biology. 22: 117. PMID 33892767 DOI: 10.1186/s13059-021-02324-z  0.823
2021 Broome R, Chernukhin I, Jamieson S, Kishore K, Papachristou EK, Mao SQ, Tejedo CG, Mahtey A, Theodorou V, Groen AJ, D'Santos C, Balasubramanian S, Farcas AM, Siersbæk R, Carroll JS. TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions. Cell Reports. 34: 108776. PMID 33626359 DOI: 10.1016/j.celrep.2021.108776  0.42
2020 Nappi M, Hofer A, Balasubramanian S, Gaunt MJ. Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis. Journal of the American Chemical Society. PMID 33305571 DOI: 10.1021/jacs.0c10616  0.509
2020 Xu YZ, Jenjaroenpun P, Wongsurawat T, Byrum SD, Shponka V, Tannahill D, Chavez EA, Hung SS, Steidl C, Balasubramanian S, Rimsza LM, Kendrick S. Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma. Nar Cancer. 2: zcaa029. PMID 33094287 DOI: 10.1093/narcan/zcaa029  0.695
2020 Spiegel J, Adhikari S, Balasubramanian S. The Structure and Function of DNA G-Quadruplexes. Trends in Chemistry. 2: 123-136. PMID 32923997 DOI: 10.1016/j.trechm.2019.07.002  0.439
2020 Hänsel-Hertsch R, Simeone A, Shea A, Hui WWI, Zyner KG, Marsico G, Rueda OM, Bruna A, Martin A, Zhang X, Adhikari S, Tannahill D, Caldas C, Balasubramanian S. Landscape of G-quadruplex DNA structural regions in breast cancer. Nature Genetics. PMID 32747825 DOI: 10.1038/S41588-020-0672-8  0.806
2020 Di Antonio M, Ponjavic A, Radzevičius A, Ranasinghe RT, Catalano M, Zhang X, Shen J, Needham LM, Lee SF, Klenerman D, Balasubramanian S. Single-molecule visualization of DNA G-quadruplex formation in live cells. Nature Chemistry. PMID 32690897 DOI: 10.1038/S41557-020-0506-4  0.458
2020 Mao SQ, Cuesta SM, Tannahill D, Balasubramanian S. Genome-wide DNA methylation signatures are determined by DNMT3A/B sequence preferences. Biochemistry. PMID 32543182 DOI: 10.1021/Acs.Biochem.0C00339.S001  0.757
2020 Varshney D, Spiegel J, Zyner K, Tannahill D, Balasubramanian S. The regulation and functions of DNA and RNA G-quadruplexes. Nature Reviews. Molecular Cell Biology. PMID 32313204 DOI: 10.1038/S41580-020-0236-X  0.853
2020 Liu KC, Röder K, Mayer C, Adhikari S, Wales DJ, Balasubramanian S. Affinity-selected bicyclic peptide G-quadruplex ligands mimic a protein-like binding mechanism. Journal of the American Chemical Society. PMID 32267689 DOI: 10.1021/Jacs.0C01879  0.646
2020 Bilyard MK, Becker S, Balasubramanian S. Natural, modified DNA bases. Current Opinion in Chemical Biology. 57: 1-7. PMID 32145439 DOI: 10.1016/J.Cbpa.2020.01.014  0.396
2019 Sahakyan A, Mahtey A, Kawasaki F, Balasubramanian S. A Spontaneous Ring Opening Reaction Leads to a Repair-Resistant T Oxidation Product in Genomic DNA. Chembiochem : a European Journal of Chemical Biology. PMID 31386787 DOI: 10.1002/Cbic.201900484  0.784
2019 Zyner KG, Mulhearn DS, Adhikari S, Martínez Cuesta S, Di Antonio M, Erard N, Hannon GJ, Tannahill D, Balasubramanian S. Genetic interactions of G-quadruplexes in humans. Elife. 8. PMID 31287417 DOI: 10.7554/Elife.46793  0.834
2019 Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 20: 124. PMID 31215477 DOI: 10.1186/s13059-019-1737-9  0.792
2019 Liu ZJ, Martínez Cuesta S, van Delft P, Balasubramanian S. Sequencing abasic sites in DNA at single-nucleotide resolution. Nature Chemistry. 11: 629-637. PMID 31209299 DOI: 10.1038/S41557-019-0279-9  0.411
2019 Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Molecular Cell. PMID 31031083 DOI: 10.1016/J.Molcel.2019.03.040  0.546
2019 Shendure J, Balasubramanian S, Church GM, Gilbert W, Rogers J, Schloss JA, Waterston RH. Publisher Correction: DNA sequencing at 40: past, present and future. Nature. PMID 30948799 DOI: 10.1038/S41586-019-1120-8  0.305
2019 Hofer A, Liu ZJ, Balasubramanian S. The detection, structure and function of modified DNA bases. Journal of the American Chemical Society. PMID 30896931 DOI: 10.1021/Jacs.9B01915  0.341
2019 Marsico G, Chambers VS, Sahakyan AB, McCauley P, Boutell JM, Di Antonio M, Balasubramanian S. Whole genome experimental maps of DNA G-quadruplexes in multiple species. Nucleic Acids Research. PMID 30892612 DOI: 10.1093/Nar/Gkz179  0.812
2019 Nguyen HP, Stewart S, Kukwikila MN, Jones SF, Offenbartl-Stiegert D, Mao S, Balasubramanian S, Beck S, Howorka S. Opto-epigenetic modulation of DNA methylation with a photo-responsive small-molecule approach. Angewandte Chemie (International Ed. in English). PMID 30773767 DOI: 10.1002/Anie.201901139  0.586
2019 Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 20: 11. PMID 30635026 DOI: 10.1186/S13059-019-1623-5  0.792
2019 Zyner KG, Mulhearn DS, Adhikari S, Cuesta SM, Antonio MD, Erard N, Hannon GJ, Tannahill D, Balasubramanian S. Author response: Genetic interactions of G-quadruplexes in humans Elife. DOI: 10.7554/Elife.46793.033  0.665
2018 Murat P, Marsico G, Herdy B, Ghanbarian AT, Portella G, Balasubramanian S. RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs. Genome Biology. 19: 229. PMID 30591072 DOI: 10.1186/S13059-018-1602-2  0.804
2018 Sengar A, Vandana JJ, Chambers VS, Di Antonio M, Winnerdy FR, Balasubramanian S, Phan AT. Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter. Nucleic Acids Research. PMID 30551210 DOI: 10.1093/Nar/Gky1179  0.531
2018 Raiber EA, Portella G, Martínez Cuesta S, Hardisty R, Murat P, Li Z, Iurlaro M, Dean W, Spindel J, Beraldi D, Liu Z, Dawson MA, Reik W, Balasubramanian S. 5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells. Nature Chemistry. PMID 30349137 DOI: 10.1038/S41557-018-0149-X  0.803
2018 Mao SQ, Ghanbarian AT, Spiegel J, Martínez Cuesta S, Beraldi D, Di Antonio M, Marsico G, Hänsel-Hertsch R, Tannahill D, Balasubramanian S. DNA G-quadruplex structures mold the DNA methylome. Nature Structural & Molecular Biology. PMID 30275516 DOI: 10.1038/S41594-018-0131-8  0.835
2018 Herdy B, Mayer C, Varshney D, Marsico G, Murat P, Taylor C, D'Santos C, Tannahill D, Balasubramanian S. Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts. Nucleic Acids Research. PMID 30256975 DOI: 10.1093/Nar/Gky861  0.813
2018 Kwok CK, Marsico G, Balasubramanian S. Detecting RNA G-Quadruplexes (rG4s) in the Transcriptome. Cold Spring Harbor Perspectives in Biology. 10. PMID 29967010 DOI: 10.1101/Cshperspect.A032284  0.769
2018 Chen MC, Tippana R, Demeshkina NA, Murat P, Balasubramanian S, Myong S, Ferré-D'Amaré AR. Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature. PMID 29899445 DOI: 10.1038/S41586-018-0209-9  0.725
2018 Kawasaki F, Martínez Cuesta S, Beraldi D, Mahtey A, Hardisty RE, Carrington M, Balasubramanian S. Sequencing 5-hydroxymethyluracil at single-base resolution. Angewandte Chemie (International Ed. in English). PMID 29882366 DOI: 10.1002/Anie.201804046  0.793
2018 Parry AJ, Hoare M, Bihary D, Hänsel-Hertsch R, Smith S, Tomimatsu K, Mannion E, Smith A, D'Santos P, Russell IA, Balasubramanian S, Kimura H, Samarajiwa SA, Narita M. NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence. Nature Communications. 9: 1840. PMID 29743479 DOI: 10.1038/S41467-018-04283-9  0.78
2018 Hänsel-Hertsch R, Spiegel J, Marsico G, Tannahill D, Balasubramanian S. Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing. Nature Protocols. 13: 551-564. PMID 29470465 DOI: 10.1038/Nprot.2017.150  0.848
2018 Marchetti C, Zyner KG, Ohnmacht SA, Robson M, Haider SM, Morton JP, Marsico G, Vo T, Laughlin-Toth S, Ahmed AA, Di Vita G, Pazitna I, Gunaratnam M, Besser RJ, Andrade AC, ... ... Balasubramanian S, et al. Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule. Journal of Medicinal Chemistry. PMID 29356532 DOI: 10.1021/Acs.Jmedchem.7B01781  0.804
2017 Raiber EA, Beraldi D, Martínez Cuesta S, McInroy GR, Kingsbury Z, Becq J, James T, Lopes M, Allinson K, Field S, Humphray S, Santarius T, Watts C, Bentley D, Balasubramanian S. Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma. Npj Genomic Medicine. 2: 6. PMID 29263824 DOI: 10.1038/S41525-017-0007-6  0.786
2017 Sahakyan AB, Chambers VS, Marsico G, Santner T, Di Antonio M, Balasubramanian S. Machine learning model for sequence-driven DNA G-quadruplex formation. Scientific Reports. 7: 14535. PMID 29109402 DOI: 10.1038/S41598-017-14017-4  0.835
2017 Guilbaud G, Murat P, Recolin B, Campbell BC, Maiter A, Sale JE, Balasubramanian S. Local epigenetic reprogramming induced by G-quadruplex ligands. Nature Chemistry. 9: 1110-1117. PMID 29064488 DOI: 10.1038/Nchem.2828  0.687
2017 Shendure J, Balasubramanian S, Church GM, Gilbert W, Rogers J, Schloss JA, Waterston RH. DNA sequencing at 40: past, present and future. Nature. PMID 29019985 DOI: 10.1038/Nature24286  0.403
2017 Balasubramanian S, Tanpure AA. Synthesis and multiple incorporations of 2'-O-methyl-5-hydroxymethyl-, 5-hydroxymethyl- and 5-formylcytidine monomers into RNA oligonucleotides. Chembiochem : a European Journal of Chemical Biology. PMID 28901692 DOI: 10.1002/Cbic.201700492  0.319
2017 van Delft P, Akay A, Huber SM, Bueschl C, Rudolph KLM, Di Domenico T, Schuhmacher R, Miska EA, Balasubramanian S. The Profile and Dynamics of RNA Modifications in Animals. Chembiochem : a European Journal of Chemical Biology. PMID 28449301 DOI: 10.1002/Cbic.201700093  0.304
2017 Hänsel-Hertsch R, Antonio MD, Balasubramanian S. DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential. Nature Reviews. Molecular Cell Biology. PMID 28225080 DOI: 10.1038/Nrm.2017.3  0.851
2017 Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, ... ... Balasubramanian S, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nature Communications. 8: 14432. PMID 28211448 DOI: 10.1038/Ncomms14432  0.47
2017 Milagre I, Stubbs TM, King MR, Spindel J, Santos F, Krueger F, Bachman M, Segonds-Pichon A, Balasubramanian S, Andrews SR, Dean W, Reik W. Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming. Cell Reports. 18: 1079-1089. PMID 28147265 DOI: 10.1016/J.Celrep.2017.01.008  0.37
2017 Kawasaki F, Beraldi D, Hardisty RE, McInroy GR, van Delft P, Balasubramanian S. Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania. Genome Biology. 18: 23. PMID 28137275 DOI: 10.1186/S13059-017-1150-1  0.751
2017 Sahakyan AB, Murat P, Mayer C, Balasubramanian S. G-quadruplex structures within the 3' UTR of LINE-1 elements stimulate retrotransposition. Nature Structural & Molecular Biology. PMID 28134931 DOI: 10.1038/Nsmb.3367  0.812
2017 Huber SM, van Delft P, Tanpure AA, Miska EA, Balasubramanian S. 2'-O-methyl-5-hydroxymethylcytidine - a second oxidative derivative of 5-methylcytidine in RNA. Journal of the American Chemical Society. PMID 28107630 DOI: 10.1021/Jacs.6B12180  0.305
2017 Sahakyan AB, Balasubramanian S. Single genome retrieval of context-dependent variability in mutation rates for human germline. Bmc Genomics. 18: 81. PMID 28086752 DOI: 10.1186/S12864-016-3440-5  0.679
2017 Kawasaki F, Murat P, Li Z, Santner T, Balasubramanian S. Synthesis and biophysical analysis of modified thymine-containing DNA oligonucleotides. Chemical Communications (Cambridge, England). PMID 28074944 DOI: 10.1039/C6Cc08670E  0.814
2017 Balasubramanian S. Abstract PL04-01: G-quadruplexes and DNA dynamics Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Pl04-01  0.459
2017 Raiber E, Beraldi D, Cuesta SM, McInroy G, Kingsbury Z, Becq J, James T, Lopes M, Allinson K, Field S, Humphray S, Santarius T, Watts C, Bentley D, Balasubramanian S. GENE-46. COMPARISON OF MATCHED GLIOBLASTOMA TUMOR AND MARGIN SAMPLES USING SINGLE BASE RESOLUTION MAPS REVEALS ACQUIRED, EARLY EPIGENETIC CHANGES THAT PREDISPOSE TO MUTATIONS DURING TUMOURIGENESIS Neuro-Oncology. 19: vi102-vi102. DOI: 10.1093/Neuonc/Nox168.419  0.764
2016 Lightfoot HL, Miska EA, Balasubramanian S. Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing. Organic & Biomolecular Chemistry. PMID 27731469 DOI: 10.1039/C6Ob01945E  0.326
2016 Hänsel-Hertsch R, Beraldi D, Lensing SV, Marsico G, Zyner K, Parry A, Di Antonio M, Pike J, Kimura H, Narita M, Tannahill D, Balasubramanian S. G-quadruplex structures mark human regulatory chromatin. Nature Genetics. PMID 27618450 DOI: 10.1038/Ng.3662  0.829
2016 Kwok CK, Marsico G, Sahakyan AB, Chambers VS, Balasubramanian S. rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome. Nature Methods. PMID 27571552 DOI: 10.1038/Nmeth.3965  0.818
2016 Lensing SV, Marsico G, Hänsel-Hertsch R, Lam EY, Tannahill D, Balasubramanian S. DSBCapture: in situ capture and sequencing of DNA breaks. Nature Methods. PMID 27525976 DOI: 10.1038/Nmeth.3960  0.81
2016 Mayer C, McInroy GR, Murat P, Van Delft P, Balasubramanian S. An Epigenetics-Inspired DNA-Based Data Storage System. Angewandte Chemie (International Ed. in English). PMID 27440712 DOI: 10.1002/Anie.201605531  0.71
2016 Iurlaro M, McInroy GR, Burgess HE, Dean W, Raiber EA, Bachman M, Beraldi D, Balasubramanian S, Reik W. In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine. Genome Biology. 17: 141. PMID 27356509 DOI: 10.1186/S13059-016-1001-5  0.8
2016 Kwok CK, Sahakyan AB, Balasubramanian S. Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA. Angewandte Chemie (International Ed. in English). PMID 27355429 DOI: 10.1002/Anie.201603562  0.801
2016 Adam J, Adamová D, Aggarwal MM, Aglieri Rinella G, Agnello M, Agrawal N, Ahammed Z, Ahmad S, Ahn SU, Aiola S, Akindinov A, Alam SN, Aleksandrov D, Alessandro B, Alexandre D, ... ... Balasubramanian S, et al. Centrality Dependence of the Charged-Particle Multiplicity Density at Midrapidity in Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV. Physical Review Letters. 116: 222302. PMID 27314715 DOI: 10.1103/Physrevlett.116.222302  0.425
2016 Adam J, Adamová D, Aggarwal MM, Aglieri Rinella G, Agnello M, Agrawal N, Ahammed Z, Ahmad S, Ahn SU, Aiola S, Akindinov A, Alam SN, Aleksandrov D, Alessandro B, Alexandre D, ... ... Balasubramanian S, et al. Production of K[Formula: see text](892)[Formula: see text] and [Formula: see text](1020) in p-Pb collisions at [Formula: see text] = 5.02 TeV. The European Physical Journal. C, Particles and Fields. 76: 245. PMID 27217821 DOI: 10.1140/Epjc/S10052-016-4088-7  0.426
2016 Adam J, Adamová D, Aggarwal MM, Aglieri Rinella G, Agnello M, Agrawal N, Ahammed Z, Ahmad S, Ahn SU, Aiola S, Akindinov A, Alam SN, Albuquerque DS, Aleksandrov D, Alessandro B, ... ... Balasubramanian S, et al. Anisotropic Flow of Charged Particles in Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV. Physical Review Letters. 116: 132302. PMID 27081971 DOI: 10.1103/Physrevlett.116.132302  0.421
2016 McInroy GR, Beraldi D, Raiber EA, Modrzynska K, van Delft P, Billker O, Balasubramanian S. Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments. Plos One. 11: e0152322. PMID 27031619 DOI: 10.1371/Journal.Pone.0152322  0.814
2016 Sahakyan AB, Balasubramanian S. Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases. Bmc Genomics. 17: 225. PMID 26968808 DOI: 10.1186/S12864-016-2582-9  0.67
2016 Cording A, Gormally M, Bond PJ, Carrington M, Balasubramanian S, Miska EA, Thomas B. Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications. Rna Biology. 0. PMID 26786754 DOI: 10.1080/15476286.2015.1137422  0.322
2016 Walker OS, Elsässer SJ, Mahesh M, Bachman M, Balasubramanian S, Chin JW. Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes. Journal of the American Chemical Society. PMID 26761588 DOI: 10.1021/Jacs.5B07627  0.339
2016 Gormally M, Marsico G, Rai G, Lowe C, Thomas C, Maloney D, Michael S, Matak-Vincovic D, Jadhav A, Simeonov A, Balasubramanian S. Abstract 3088: Transcription factor as target: Novel small molecule inhibits FOXM1 DNA binding and oncogenic gene products Cancer Research. 76: 3088-3088. DOI: 10.1158/1538-7445.Am2016-3088  0.402
2016 Lensing S, Marsico G, Hänsel-Hertsch R, Lam E, Tannahill D, Balasubramanian S. DSBCapture: in situ single-nucleotide resolution DNA double-strand break mapping Protocol Exchange. DOI: 10.1038/Protex.2016.52  0.797
2016 Kwok CK, Marsico G, Sahakyan AB, Chambers VS, Balasubramanian S. Transcriptome-wide profiling of RNA G-quadruplex structures using rG4-seq Protocol Exchange. DOI: 10.1038/Protex.2016.060  0.82
2015 Patalano S, Vlasova A, Wyatt C, Ewels P, Camara F, Ferreira PG, Asher CL, Jurkowski TP, Segonds-Pichon A, Bachman M, González-Navarrete I, Minoche AE, Krueger F, Lowy E, Marcet-Houben M, ... ... Balasubramanian S, et al. Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies. Proceedings of the National Academy of Sciences of the United States of America. 112: 13970-5. PMID 26483466 DOI: 10.1073/Pnas.1515937112  0.309
2015 Yangyuoru PM, Di Antonio M, Ghimire C, Biffi G, Balasubramanian S, Mao H. Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 924-927. PMID 26300569 DOI: 10.1002/Ange.201408113  0.7
2015 Chambers VS, Marsico G, Boutell JM, Di Antonio M, Smith GP, Balasubramanian S. High-throughput sequencing of DNA G-quadruplex structures in the human genome. Nature Biotechnology. PMID 26192317 DOI: 10.1038/Nbt.3295  0.722
2015 Sanders DA, Gormally MV, Marsico G, Beraldi D, Tannahill D, Balasubramanian S. FOXM1 binds directly to non-consensus sequences in the human genome. Genome Biology. 16: 130. PMID 26100407 DOI: 10.1186/S13059-015-0696-Z  0.817
2015 Bachman M, Uribe-Lewis S, Yang X, Burgess HE, Iurlaro M, Reik W, Murrell A, Balasubramanian S. 5-Formylcytosine can be a stable DNA modification in mammals. Nature Chemical Biology. PMID 26098680 DOI: 10.1038/Nchembio.1848  0.404
2015 Hardisty RE, Kawasaki F, Sahakyan AB, Balasubramanian S. Selective Chemical Labeling of Natural T Modifications in DNA. Journal of the American Chemical Society. PMID 25946119 DOI: 10.1021/Jacs.5B03730  0.793
2015 Kwok CK, Balasubramanian S. Targeted Detection of G-Quadruplexes in Cellular RNAs. Angewandte Chemie (International Ed. in English). 54: 6751-4. PMID 25907625 DOI: 10.1002/Anie.201500891  0.699
2015 Le DD, Di Antonio M, Chan LK, Balasubramanian S. G-quadruplex ligands exhibit differential G-tetrad selectivity. Chemical Communications (Cambridge, England). 51: 8048-50. PMID 25864836 DOI: 10.1039/C5Cc02252E  0.68
2015 Field SF, Beraldi D, Bachman M, Stewart SK, Beck S, Balasubramanian S. Accurate measurement of 5-methylcytosine and 5-hydroxymethylcytosine in human cerebellum DNA by oxidative bisulfite on an array (OxBS-array). Plos One. 10: e0118202. PMID 25706862 DOI: 10.1371/Journal.Pone.0118202  0.738
2015 Huber SM, van Delft P, Mendil L, Bachman M, Smollett K, Werner F, Miska EA, Balasubramanian S. Formation and abundance of 5-hydroxymethylcytosine in RNA. Chembiochem : a European Journal of Chemical Biology. 16: 752-5. PMID 25676849 DOI: 10.1002/Cbic.201500013  0.306
2015 Chen MC, Murat P, Abecassis K, Ferré-D'Amaré AR, Balasubramanian S. Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase. Nucleic Acids Research. 43: 2223-31. PMID 25653156 DOI: 10.1093/Nar/Gkv051  0.697
2015 Raiber EA, Murat P, Chirgadze DY, Beraldi D, Luisi BF, Balasubramanian S. 5-Formylcytosine alters the structure of the DNA double helix. Nature Structural & Molecular Biology. 22: 44-9. PMID 25504322 DOI: 10.1038/Nsmb.2936  0.825
2015 Yangyuoru PM, Di Antonio M, Ghimire C, Biffi G, Balasubramanian S, Mao H. Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex. Angewandte Chemie (International Ed. in English). 54: 910-3. PMID 25421962 DOI: 10.1002/anie.201408113  0.672
2015 Balasubramanian S. Solexa sequencing: decoding genomes on a population scale. Clinical Chemistry. 61: 21-4. PMID 25332311 DOI: 10.1373/Clinchem.2014.221747  0.392
2015 Booth MJ, Raiber EA, Balasubramanian S. Chemical methods for decoding cytosine modifications in DNA. Chemical Reviews. 115: 2240-54. PMID 25094039 DOI: 10.1021/Cr5002904  0.788
2015 Kendrick SL, Tannahill D, Balasubramanian S, Rimsza LM. Concurrent BCL2 / MYC Gene Amplification Associates with Increased DNA G-Quadruplex Formation in DLBCL Blood. 126: 2641-2641. DOI: 10.1182/Blood.V126.23.2641.2641  0.717
2015 McInroy GR, Bell NM, Ficz G, Balasubramanian S, Reik W, Raiber EA. The biology and genomic localization of cytosine modifications Epigenetics and Human Health. 4: 167-191. DOI: 10.1007/978-3-642-31974-7_8  0.707
2014 Bachman M, Uribe-Lewis S, Yang X, Williams M, Murrell A, Balasubramanian S. 5-Hydroxymethylcytosine is a predominantly stable DNA modification. Nature Chemistry. 6: 1049-55. PMID 25411882 DOI: 10.1038/Nchem.2064  0.408
2014 Gormally MV, Dexheimer TS, Marsico G, Sanders DA, Lowe C, Matak-Vinkovi? D, Michael S, Jadhav A, Rai G, Maloney DJ, Simeonov A, Balasubramanian S. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nature Communications. 5: 5165. PMID 25387393 DOI: 10.1038/Ncomms6165  0.663
2014 Müller S, Laxmi-Reddy K, Jena PV, Baptiste B, Dong Z, Godde F, Ha T, Rodriguez R, Balasubramanian S, Huc I. Targeting DNA G-quadruplexes with helical small molecules. Chembiochem : a European Journal of Chemical Biology. 15: 2563-70. PMID 25256604 DOI: 10.1002/Cbic.201402439  0.514
2014 Schiavone D, Guilbaud G, Murat P, Papadopoulou C, Sarkies P, Prioleau MN, Balasubramanian S, Sale JE. Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells. The Embo Journal. 33: 2507-20. PMID 25190518 DOI: 10.15252/Embj.201488398  0.684
2014 McInroy GR, Raiber EA, Balasubramanian S. Chemical biology of genomic DNA: minimizing PCR bias. Chemical Communications (Cambridge, England). 50: 12047-9. PMID 25178041 DOI: 10.1039/C4Cc05107F  0.769
2014 Wang I, Kowalski MP, Langley AR, Rodriguez R, Balasubramanian S, Hsu ST, Krude T. Nucleotide contributions to the structural integrity and DNA replication initiation activity of noncoding y RNA. Biochemistry. 53: 5848-63. PMID 25151917 DOI: 10.1021/Bi500470B  0.432
2014 Biffi G, Tannahill D, Miller J, Howat WJ, Balasubramanian S. Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues. Plos One. 9: e102711. PMID 25033211 DOI: 10.1371/Journal.Pone.0102711  0.811
2014 Balasubramanian S. Chemical biology on the genome. Bioorganic & Medicinal Chemistry. 22: 4356-70. PMID 24957879 DOI: 10.1016/J.Bmc.2014.05.016  0.453
2014 Booth MJ, Marsico G, Bachman M, Beraldi D, Balasubramanian S. Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution. Nature Chemistry. 6: 435-40. PMID 24755596 DOI: 10.1038/Nchem.1893  0.791
2014 Di Antonio M, McLuckie KI, Balasubramanian S. Reprogramming the mechanism of action of chlorambucil by coupling to a G-quadruplex ligand. Journal of the American Chemical Society. 136: 5860-3. PMID 24697838 DOI: 10.1021/Ja5014344  0.449
2014 Murat P, Zhong J, Lekieffre L, Cowieson NP, Clancy JL, Preiss T, Balasubramanian S, Khanna R, Tellam J. G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation. Nature Chemical Biology. 10: 358-64. PMID 24633353 DOI: 10.1038/Nchembio.1479  0.625
2014 Murat P, Balasubramanian S. Existence and consequences of G-quadruplex structures in DNA. Current Opinion in Genetics & Development. 25: 22-9. PMID 24584093 DOI: 10.1016/J.Gde.2013.10.012  0.69
2014 Nasiri HR, Bell NM, McLuckie KI, Husby J, Abell C, Neidle S, Balasubramanian S. Targeting a c-MYC G-quadruplex DNA with a fragment library. Chemical Communications (Cambridge, England). 50: 1704-7. PMID 24394582 DOI: 10.1039/C3Cc48390H  0.589
2014 Biffi G, Di Antonio M, Tannahill D, Balasubramanian S. Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nature Chemistry. 6: 75-80. PMID 24345950 DOI: 10.1038/Nchem.1805  0.827
2014 Booth MJ, Marsico G, Bachman M, Beraldi D, Balasubramanian S. Addendum: Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution Nature Chemistry. 6: 553-553. DOI: 10.1038/Nchem.1959  0.781
2013 Bell NM, L'Hernault A, Murat P, Richards JE, Lever AM, Balasubramanian S. Targeting RNA-protein interactions within the human immunodeficiency virus type 1 lifecycle. Biochemistry. 52: 9269-74. PMID 24358934 DOI: 10.1021/Bi401270D  0.593
2013 Wu L, Murat P, Matak-Vinkovic D, Murrell A, Balasubramanian S. Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins. Biochemistry. 52: 9519-27. PMID 24320048 DOI: 10.1021/Bi401085H  0.602
2013 Iurlaro M, Ficz G, Oxley D, Raiber EA, Bachman M, Booth MJ, Andrews S, Balasubramanian S, Reik W. A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biology. 14: R119. PMID 24156278 DOI: 10.1186/Gb-2013-14-10-R119  0.775
2013 Yangyuoru PM, Zhang AY, Shi Z, Koirala D, Balasubramanian S, Mao H. Mechanochemical properties of individual human telomeric RNA (TERRA) G-quadruplexes. Chembiochem : a European Journal of Chemical Biology. 14: 1931-5. PMID 24038851 DOI: 10.1002/Cbic.201300350  0.428
2013 Booth MJ, Ost TW, Beraldi D, Bell NM, Branco MR, Reik W, Balasubramanian S. Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nature Protocols. 8: 1841-51. PMID 24008380 DOI: 10.1038/Nprot.2013.115  0.689
2013 Murat P, Gormally MV, Sanders D, Di Antonio M, Balasubramanian S. Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand. Chemical Communications (Cambridge, England). 49: 8453-5. PMID 23949446 DOI: 10.1039/C3Cc44737E  0.616
2013 McLuckie KI, Di Antonio M, Zecchini H, Xian J, Caldas C, Krippendorff BF, Tannahill D, Lowe C, Balasubramanian S. G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells. Journal of the American Chemical Society. 135: 9640-3. PMID 23782415 DOI: 10.1021/Ja404868T  0.72
2013 Lam EY, Beraldi D, Tannahill D, Balasubramanian S. G-quadruplex structures are stable and detectable in human genomic DNA. Nature Communications. 4: 1796. PMID 23653208 DOI: 10.1038/Ncomms2792  0.857
2013 Biffi G, Tannahill D, McCafferty J, Balasubramanian S. Quantitative visualization of DNA G-quadruplex structures in human cells. Nature Chemistry. 5: 182-6. PMID 23422559 DOI: 10.1038/Nchem.1548  0.83
2013 Mitchell T, Ramos-Montoya A, Di Antonio M, Murat P, Ohnmacht S, Micco M, Jurmeister S, Fryer L, Balasubramanian S, Neidle S, Neal DE. Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer. Biochemistry. 52: 1429-36. PMID 23363071 DOI: 10.1021/Bi301349C  0.651
2013 Sanders DA, Ross-Innes CS, Beraldi D, Carroll JS, Balasubramanian S. Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells. Genome Biology. 14: R6. PMID 23347430 DOI: 10.1186/Gb-2013-14-1-R6  0.672
2013 Nikan M, Di Antonio M, Abecassis K, McLuckie K, Balasubramanian S. An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes. Angewandte Chemie (International Ed. in English). 52: 1428-31. PMID 23238938 DOI: 10.1002/Anie.201207075  0.813
2013 Mitchell T, Ramos-Montoya A, Di Antonio M, Murat P, Ohnmacht S, Micco M, Fryer L, Balasubramanian S, Neidle S, Neal D. 823 Transcriptional down-regulation of the androgen receptor by promoter G-quadruplex stabilisation; a potential alternative treatment in castrate-resistant prostate cancer European Urology Supplements. 12: e823-e824. DOI: 10.1016/S1569-9056(13)61303-2  0.585
2012 Bugaut A, Murat P, Balasubramanian S. An RNA hairpin to G-quadruplex conformational transition. Journal of the American Chemical Society. 134: 19953-6. PMID 23190255 DOI: 10.1021/Ja308665G  0.658
2012 Zhang AY, Balasubramanian S. The kinetics and folding pathways of intramolecular G-quadruplex nucleic acids. Journal of the American Chemical Society. 134: 19297-308. PMID 23113843 DOI: 10.1021/Ja309851T  0.493
2012 Di Antonio M, Biffi G, Mariani A, Raiber EA, Rodriguez R, Balasubramanian S. Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry. Angewandte Chemie (International Ed. in English). 51: 11073-8. PMID 23038154 DOI: 10.1002/Anie.201206281  0.828
2012 Raiber EA, Beraldi D, Ficz G, Burgess HE, Branco MR, Murat P, Oxley D, Booth MJ, Reik W, Balasubramanian S. Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biology. 13: R69. PMID 22902005 DOI: 10.1186/Gb-2012-13-8-R69  0.812
2012 Müller S, Sanders DA, Di Antonio M, Matsis S, Riou JF, Rodriguez R, Balasubramanian S. Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells. Organic & Biomolecular Chemistry. 10: 6537-46. PMID 22790277 DOI: 10.1039/C2Ob25830G  0.479
2012 Biffi G, Tannahill D, Balasubramanian S. An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2. Journal of the American Chemical Society. 134: 11974-6. PMID 22780456 DOI: 10.1021/Ja305734X  0.819
2012 Booth MJ, Branco MR, Ficz G, Oxley D, Krueger F, Reik W, Balasubramanian S. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science (New York, N.Y.). 336: 934-7. PMID 22539555 DOI: 10.1126/Science.1220671  0.418
2012 Bell NM, Kenyon JC, Balasubramanian S, Lever AM. Comparative structural effects of HIV-1 Gag and nucleocapsid proteins in binding to and unwinding of the viral RNA packaging signal. Biochemistry. 51: 3162-9. PMID 22448757 DOI: 10.1021/Bi2017969  0.337
2012 Bugaut A, Balasubramanian S. 5'-UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Research. 40: 4727-41. PMID 22351747 DOI: 10.1093/Nar/Gks068  0.468
2012 Di Antonio M, Rodriguez R, Balasubramanian S. Experimental approaches to identify cellular G-quadruplex structures and functions. Methods (San Diego, Calif.). 57: 84-92. PMID 22343041 DOI: 10.1016/J.Ymeth.2012.01.008  0.547
2012 Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nature Chemical Biology. 8: 301-10. PMID 22306580 DOI: 10.1038/Nchembio.780  0.792
2012 Mela I, Kranaster R, Henderson RM, Balasubramanian S, Edwardson JM. Demonstration of ligand decoration, and ligand-induced perturbation, of G-quadruplexes in a plasmid using atomic force microscopy. Biochemistry. 51: 578-85. PMID 22225525 DOI: 10.1021/Bi201600G  0.821
2012 Dash J, Das RN, Hegde N, PantoÅŸ GD, Shirude PS, Balasubramanian S. Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 554-64. PMID 22161991 DOI: 10.1002/Chem.201102556  0.756
2012 Sarkies P, Murat P, Phillips LG, Patel KJ, Balasubramanian S, Sale JE. FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Research. 40: 1485-98. PMID 22021381 DOI: 10.1093/Nar/Gkr868  0.709
2012 Raiber EA, Kranaster R, Lam E, Nikan M, Balasubramanian S. A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro. Nucleic Acids Research. 40: 1499-508. PMID 22021377 DOI: 10.1093/Nar/Gkr882  0.813
2012 Di Antonio M, Biffi G, Mariani A, Raiber E, Rodriguez R, Balasubramanian S. Inside Cover: Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry (Angew. Chem. Int. Ed. 44/2012) Angewandte Chemie International Edition. 51: 10906-10906. DOI: 10.1002/Anie.201207794  0.835
2012 Di Antonio M, Biffi G, Mariani A, Raiber E, Rodriguez R, Balasubramanian S. Innentitelbild: Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry (Angew. Chem. 44/2012) Angewandte Chemie. 124: 11064-11064. DOI: 10.1002/Ange.201207794  0.836
2011 Balasubramanian S. Decoding genomes at high speed: implications for science and medicine. Angewandte Chemie (International Ed. in English). 50: 12406-10. PMID 22144295 DOI: 10.1002/Anie.201106707  0.309
2011 Koirala D, Dhakal S, Ashbridge B, Sannohe Y, Rodriguez R, Sugiyama H, Balasubramanian S, Mao H. A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. Nature Chemistry. 3: 782-7. PMID 21941250 DOI: 10.1038/Nchem.1126  0.432
2011 Hegde NS, Sanders DA, Rodriguez R, Balasubramanian S. The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. Nature Chemistry. 3: 725-31. PMID 21860463 DOI: 10.1038/Nchem.1114  0.369
2011 Lightfoot HL, Bugaut A, Armisen J, Lehrbach NJ, Miska EA, Balasubramanian S. A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. Biochemistry. 50: 7514-21. PMID 21815640 DOI: 10.1021/Bi200851D  0.458
2011 Zhang AY, Bugaut A, Balasubramanian S. A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology. Biochemistry. 50: 7251-8. PMID 21744844 DOI: 10.1021/Bi200805J  0.525
2011 Balasubramanian S, Hurley LH, Neidle S. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nature Reviews. Drug Discovery. 10: 261-75. PMID 21455236 DOI: 10.1038/Nrd3428  0.459
2011 Smith JS, Chen Q, Yatsunyk LA, Nicoludis JM, Garcia MS, Kranaster R, Balasubramanian S, Monchaud D, Teulade-Fichou MP, Abramowitz L, Schultz DC, Johnson FB. Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae. Nature Structural & Molecular Biology. 18: 478-85. PMID 21399640 DOI: 10.1038/Nsmb.2033  0.825
2011 Dash J, Waller ZA, Panto? GD, Balasubramanian S. Synthesis and binding studies of novel diethynyl-pyridine amides with genomic promoter DNA G-quadruplexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 4571-81. PMID 21387430 DOI: 10.1002/Chem.201003157  0.847
2011 McLuckie KI, Waller ZA, Sanders DA, Alves D, Rodriguez R, Dash J, McKenzie GJ, Venkitaraman AR, Balasubramanian S. G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells. Journal of the American Chemical Society. 133: 2658-63. PMID 21294544 DOI: 10.1021/Ja109474C  0.843
2010 Bejugam M, Gunaratnam M, Müller S, Sanders DA, Sewitz S, Fletcher JA, Neidle S, Balasubramanian S. Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines. Acs Medicinal Chemistry Letters. 1: 306-10. PMID 24900212 DOI: 10.1021/Ml100062Z  0.437
2010 Müller S, Kumari S, Rodriguez R, Balasubramanian S. Small-molecule-mediated G-quadruplex isolation from human cells. Nature Chemistry. 2: 1095-8. PMID 21107376 DOI: 10.1038/Nchem.842  0.531
2010 Marnef A, Maldonado M, Bugaut A, Balasubramanian S, Kress M, Weil D, Standart N. Distinct functions of maternal and somatic Pat1 protein paralogs. Rna (New York, N.Y.). 16: 2094-107. PMID 20826699 DOI: 10.1261/Rna.2295410  0.316
2010 Shahid R, Bugaut A, Balasubramanian S. The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression. Biochemistry. 49: 8300-6. PMID 20726580 DOI: 10.1021/Bi100957H  0.446
2010 Bugaut A, Rodriguez R, Kumari S, Hsu ST, Balasubramanian S. Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex. Organic & Biomolecular Chemistry. 8: 2771-6. PMID 20436976 DOI: 10.1039/C002418J  0.419
2010 Yeoman JA, Orte A, Ashbridge B, Klenerman D, Balasubramanian S. RNA conformation in catalytically active human telomerase. Journal of the American Chemical Society. 132: 2852-3. PMID 20148555 DOI: 10.1021/Ja909383N  0.331
2010 Fegan A, Shirude PS, Ying L, Balasubramanian S. Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes. Chemical Communications (Cambridge, England). 46: 946-8. PMID 20107659 DOI: 10.1039/B920680A  0.39
2010 Bejugam M, Gunaratnam M, Müller S, Sanders DA, Sewitz S, Fletcher JA, Neidle S, Balasubramanian S. Correction to Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines Acs Medicinal Chemistry Letters. 1: 546-546. DOI: 10.1021/Ml100241W  0.356
2009 Fernando H, Sewitz S, Darot J, Tavaré S, Huppert JL, Balasubramanian S. Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression. Nucleic Acids Research. 37: 6716-22. PMID 19745055 DOI: 10.1093/Nar/Gkp740  0.675
2009 Hsu STD, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics Journal of the American Chemical Society. 131: 13399-13409. PMID 19705869 DOI: 10.1021/Ja904007P  0.445
2009 Waller ZA, Sewitz SA, Hsu ST, Balasubramanian S. A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression. Journal of the American Chemical Society. 131: 12628-33. PMID 19689109 DOI: 10.1021/Ja901892U  0.836
2009 Jena PV, Shirude PS, Okumus B, Laxmi-Reddy K, Godde F, Huc I, Balasubramanian S, Ha T. G-quadruplex DNA bound by a synthetic ligand is highly dynamic. Journal of the American Chemical Society. 131: 12522-3. PMID 19685880 DOI: 10.1021/Ja903408R  0.465
2009 Balasubramanian S, Neidle S. G-quadruplex nucleic acids as therapeutic targets Current Opinion in Chemical Biology. 13: 345-353. PMID 19515602 DOI: 10.1016/J.Cbpa.2009.04.637  0.469
2009 Müller S, Panto? GD, Rodriguez R, Balasubramanian S. Controlled-folding of a small molecule modulates DNA G-quadruplex recognition. Chemical Communications (Cambridge, England). 80-2. PMID 19082005 DOI: 10.1039/B816861J  0.455
2009 Redman JE, Granadino-Roldán JM, Schouten JA, Ladame S, Reszka AP, Neidle S, Balasubramanian S. Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates. Organic & Biomolecular Chemistry. 7: 76-84. PMID 19081949 DOI: 10.1039/B814682A  0.738
2008 Kumari S, Bugaut A, Balasubramanian S. Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene. Biochemistry. 47: 12664-9. PMID 18991403 DOI: 10.1021/Bi8010797  0.459
2008 Bentley DR, Balasubramanian S, Swerdlow HP, Smith GP, Milton J, Brown CG, Hall KP, Evers DJ, Barnes CL, Bignell HR, Boutell JM, Bryant J, Carter RJ, Keira Cheetham R, Cox AJ, et al. Accurate whole human genome sequencing using reversible terminator chemistry. Nature. 456: 53-9. PMID 18987734 DOI: 10.1038/Nature07517  0.64
2008 Dash J, Shirude PS, Hsu ST, Balasubramanian S. Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes. Journal of the American Chemical Society. 130: 15950-6. PMID 18980309 DOI: 10.1021/Ja8046552  0.663
2008 London TB, Barber LJ, Mosedale G, Kelly GP, Balasubramanian S, Hickson ID, Boulton SJ, Hiom K. FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. The Journal of Biological Chemistry. 283: 36132-9. PMID 18978354 DOI: 10.1074/Jbc.M808152200  0.528
2008 Rodriguez R, Müller S, Yeoman JA, Trentesaux C, Riou JF, Balasubramanian S. A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres. Journal of the American Chemical Society. 130: 15758-9. PMID 18975896 DOI: 10.1021/Ja805615W  0.465
2008 Huppert JL, Bugaut A, Kumari S, Balasubramanian S. G-quadruplexes: the beginning and end of UTRs. Nucleic Acids Research. 36: 6260-8. PMID 18832370 DOI: 10.1093/Nar/Gkn511  0.479
2008 Fernando H, Rodriguez R, Balasubramanian S. Selective recognition of a DNA G-quadruplex by an engineered antibody. Biochemistry. 47: 9365-71. PMID 18702511 DOI: 10.1021/Bi800983U  0.519
2008 Dash J, Shirude PS, Balasubramanian S. G-quadruplex recognition by bis-indole carboxamides. Chemical Communications (Cambridge, England). 3055-7. PMID 18688346 DOI: 10.1039/B806042H  0.682
2008 Shirude PS, Ying L, Balasubramanian S. Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC. Chemical Communications (Cambridge, England). 2007-9. PMID 18536803 DOI: 10.1039/B801465E  0.435
2008 Fegan A, Shirude PS, Balasubramanian S. Rigid cyanine dye nucleic acid labels. Chemical Communications (Cambridge, England). 2004-6. PMID 18536802 DOI: 10.1039/B801629A  0.355
2008 Alves D, Li H, Codrington R, Orte A, Ren X, Klenerman D, Balasubramanian S. Single-molecule analysis of human telomerase monomer. Nature Chemical Biology. 4: 287-9. PMID 18391947 DOI: 10.1038/Nchembio.82  0.34
2008 Waller ZA, Shirude PS, Rodriguez R, Balasubramanian S. Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition. Chemical Communications (Cambridge, England). 1467-9. PMID 18338058 DOI: 10.1039/B718854D  0.826
2008 Bugaut A, Jantos K, Wietor JL, Rodriguez R, Sanders JK, Balasubramanian S. Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry. Angewandte Chemie (International Ed. in English). 47: 2677-80. PMID 18300215 DOI: 10.1002/Anie.200705589  0.371
2008 Shirude PS, Balasubramanian S. Single molecule conformational analysis of DNA G-quadruplexes. Biochimie. 90: 1197-206. PMID 18295608 DOI: 10.1016/J.Biochi.2008.01.015  0.471
2008 Bugaut A, Balasubramanian S. A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. Biochemistry. 47: 689-97. PMID 18092816 DOI: 10.1021/Bi701873C  0.458
2007 Bejugam M, Sewitz S, Shirude PS, Rodriguez R, Shahid R, Balasubramanian S. Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. Journal of the American Chemical Society. 129: 12926-7. PMID 17918848 DOI: 10.1021/Ja075881P  0.472
2007 Shirude PS, Gillies ER, Ladame S, Godde F, Shin-Ya K, Huc I, Balasubramanian S. Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. Journal of the American Chemical Society. 129: 11890-1. PMID 17845042 DOI: 10.1021/Ja073775H  0.704
2007 Rodriguez R, Panto? GD, Gonçalves DP, Sanders JK, Balasubramanian S. Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction. Angewandte Chemie (International Ed. in English). 46: 5405-7. PMID 17562537 DOI: 10.1002/Anie.200605075  0.409
2007 Shirude PS, Okumus B, Ying L, Ha T, Balasubramanian S. Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. Journal of the American Chemical Society. 129: 7484-5. PMID 17523641 DOI: 10.1021/Ja070497D  0.464
2007 Kumari S, Bugaut A, Huppert JL, Balasubramanian S. An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation. Nature Chemical Biology. 3: 218-21. PMID 17322877 DOI: 10.1038/Nchembio864  0.518
2007 Huppert JL, Balasubramanian S. G-quadruplexes in promoters throughout the human genome. Nucleic Acids Research. 35: 406-13. PMID 17169996 DOI: 10.1093/Nar/Gkl1057  0.481
2006 Gonçalves DP, Rodriguez R, Balasubramanian S, Sanders JK. Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands. Chemical Communications (Cambridge, England). 4685-7. PMID 17109036 DOI: 10.1039/B611731G  0.478
2006 Orte A, Clarke R, Balasubramanian S, Klenerman D. Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection. Analytical Chemistry. 78: 7707-15. PMID 17105162 DOI: 10.1021/Ac061122Y  0.343
2006 Redman JE, Ladame S, Reszka AP, Neidle S, Balasubramanian S. Discovery of G-quadruplex stabilizing ligands through direct ELISA of a one-bead-one-compound library. Organic & Biomolecular Chemistry. 4: 4364-9. PMID 17102882 DOI: 10.1039/B611716C  0.744
2006 Gavory G, Symmons MF, Krishnan Ghosh Y, Klenerman D, Balasubramanian S. Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling. Biochemistry. 45: 13304-11. PMID 17073451 DOI: 10.1021/Bi061150A  0.347
2006 Jantos K, Rodriguez R, Ladame S, Shirude PS, Balasubramanian S. Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands. Journal of the American Chemical Society. 128: 13662-3. PMID 17044674 DOI: 10.1021/Ja064713E  0.707
2006 Gonçalves DP, Ladame S, Balasubramanian S, Sanders JK. Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins. Organic & Biomolecular Chemistry. 4: 3337-42. PMID 17036123 DOI: 10.1039/B608494J  0.721
2006 Green JJ, Ladame S, Ying L, Klenerman D, Balasubramanian S. Investigating a quadruplex-ligand interaction by unfolding kinetics. Journal of the American Chemical Society. 128: 9809-12. PMID 16866537 DOI: 10.1021/Ja0615425  0.688
2006 Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry. 45: 7854-60. PMID 16784237 DOI: 10.1021/Bi0601510  0.692
2006 Ren X, Li H, Clarke RW, Alves DA, Ying L, Klenerman D, Balasubramanian S. Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy. Journal of the American Chemical Society. 128: 4992-5000. PMID 16608333 DOI: 10.1021/Ja056613Z  0.351
2006 Liu D, Bruckbauer A, Abell C, Balasubramanian S, Kang DJ, Klenerman D, Zhou D. A reversible pH-driven DNA nanoswitch array. Journal of the American Chemical Society. 128: 2067-71. PMID 16464109 DOI: 10.1021/Ja0568300  0.64
2006 Ladame S, Schouten JA, Roldan J, Redman JE, Neidle S, Balasubramanian S. Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein. Biochemistry. 45: 1393-9. PMID 16445281 DOI: 10.1021/Bi050229X  0.771
2006 Neidle S, Balasubramanian S. Quadruplex nucleic acids. The Royal Society of Chemistry. DOI: 10.1039/9781847555298  0.485
2005 Shu W, Liu D, Watari M, Riener CK, Strunz T, Welland ME, Balasubramanian S, McKendry RA. DNA molecular motor driven micromechanical cantilever arrays. Journal of the American Chemical Society. 127: 17054-60. PMID 16316252 DOI: 10.1021/Ja0554514  0.503
2005 Ladame S, Whitney AM, Balasubramanian S. Targeting nucleic acid secondary structures with polyamides using an optimized dynamic combinatorial approach. Angewandte Chemie (International Ed. in English). 44: 5736-9. PMID 16078284 DOI: 10.1002/Anie.200501450  0.743
2005 Rankin S, Reszka AP, Huppert J, Zloh M, Parkinson GN, Todd AK, Ladame S, Balasubramanian S, Neidle S. Putative DNA quadruplex formation within the human c-kit oncogene. Journal of the American Chemical Society. 127: 10584-9. PMID 16045346 DOI: 10.1021/Ja050823U  0.704
2005 Huppert JL, Balasubramanian S. Prevalence of quadruplexes in the human genome Nucleic Acids Research. 33: 2908-2916. PMID 15914667 DOI: 10.1093/Nar/Gki609  0.46
2005 Mason SJ, Hake JL, Nairne J, Cummins WJ, Balasubramanian S. Solid-phase methods for the synthesis of cyanine dyes. The Journal of Organic Chemistry. 70: 2939-49. PMID 15822952 DOI: 10.1021/Jo0479415  0.562
2004 Hazel P, Huppert J, Balasubramanian S, Neidle S. Loop-length-dependent folding of G-quadruplexes Journal of the American Chemical Society. 126: 16405-16415. PMID 15600342 DOI: 10.1021/Ja045154J  0.392
2004 White SS, Ying L, Balasubramanian S, Klenerman D. Individual molecules of dye-labeled DNA act as a reversible two-color switch upon application of an electric field. Angewandte Chemie (International Ed. in English). 43: 5926-30. PMID 15547896 DOI: 10.1002/Anie.200460323  0.3
2004 Patel SD, Isalan M, Gavory G, Ladame S, Choo Y, Balasubramanian S. Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes. Biochemistry. 43: 13452-8. PMID 15491152 DOI: 10.1021/Bi048892T  0.726
2004 Ladame S, Schouten JA, Stuart J, Roldan J, Neidle S, Balasubramanian S. Tetrapeptides induce selective recognition for G-quadruplexes when conjugated to a DNA-binding platform. Organic & Biomolecular Chemistry. 2: 2925-31. PMID 15480456 DOI: 10.1039/B409698C  0.749
2004 Krishnan-Ghosh Y, Liu D, Balasubramanian S. Formation of an interlocked quadruplex dimer by d(GGGT). Journal of the American Chemical Society. 126: 11009-16. PMID 15339186 DOI: 10.1021/Ja049259Y  0.483
2004 Krishnan-Ghosh Y, Stephens E, Balasubramanian S. A PNA4 quadruplex. Journal of the American Chemical Society. 126: 5944-5945. PMID 15137741 DOI: 10.1021/Ja031508F  0.408
2004 Shammas MA, Liu X, Gavory G, Raney KD, Balasubramanian S, Shmookler Reis RJ. Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells. Experimental Cell Research. 295: 204-14. PMID 15051503 DOI: 10.1016/J.Yexcr.2004.01.003  0.671
2004 Whitney AM, Ladame S, Balasubramanian S. Templated ligand assembly by using G-quadruplex DNA and dynamic covalent chemistry. Angewandte Chemie (International Ed. in English). 43: 1143-6. PMID 14983458 DOI: 10.1002/Anie.200353069  0.695
2004 Routledge A, Abell C, Balasubramanian S. An Investigation into Solid-Phase Radical Chemistry - Synthesis of Furan Rings Synlett. 1: 61-62. DOI: 10.1055/S-1997-704  0.681
2003 Liu D, Balasubramanian S. A proton-fuelled DNA nanomachine. Angewandte Chemie (International Ed. in English). 42: 5734-6. PMID 14661209 DOI: 10.1002/Anie.200352402  0.538
2003 Ying L, Green JJ, Li H, Klenerman D, Balasubramanian S. Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 100: 14629-34. PMID 14645716 DOI: 10.1073/Pnas.2433350100  0.372
2003 Schouten JA, Ladame S, Mason SJ, Cooper MA, Balasubramanian S. G-quadruplex-specific peptide-hemicyanine ligands by partial combinatorial selection. Journal of the American Chemical Society. 125: 5594-5. PMID 12733873 DOI: 10.1021/Ja029356W  0.786
2003 Li H, Ying L, Green JJ, Balasubramanian S, Klenerman D. Ultrasensitive coincidence fluorescence detection of single DNA molecules. Analytical Chemistry. 75: 1664-70. PMID 12705600 DOI: 10.1021/Ac026367Z  0.33
2003 Green JJ, Ying L, Klenerman D, Balasubramanian S. Kinetics of unfolding the human telomeric DNA quadruplex using a PNA trap. Journal of the American Chemical Society. 125: 3763-7. PMID 12656607 DOI: 10.1021/Ja029149W  0.366
2003 Whitney A, Gavory G, Balasubramanian S. Site-specific cleavage of human telomerase RNA using PNA-neocuproine·Zn(II) derivatives Chemical Communications. 9: 36-37. DOI: 10.1039/B210135A  0.324
2002 Mason SJ, Balasubramanian S. Solid-phase catch, activate, and release synthesis of cyanine dyes. Organic Letters. 4: 4261-4. PMID 12443073 DOI: 10.1021/Ol026836J  0.552
2002 Gavory G, Farrow M, Balasubramanian S. Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro. Nucleic Acids Research. 30: 4470-80. PMID 12384594 DOI: 10.1093/Nar/Gkf575  0.585
2002 Horsey I, Krishnan-Ghosh Y, Balasubramanian S. Enhanced cooperative binding of oligonucleotides to form DNA duplexes mediated by metal ion chelation Chemical Communications. 1950-1951. PMID 12271689 DOI: 10.1039/B206054J  0.36
2002 Ladame S, Harrison RJ, Neidle S, Balasubramanian S. Solid-phase synthesis of symmetrical 3,6-bispeptide-acridone conjugates. Organic Letters. 4: 2509-12. PMID 12123363 DOI: 10.1021/Ol026130P  0.675
2001 Wallace MI, Ying L, Balasubramanian S, Klenerman D. Non-arrhenius kinetics for the loop closure of a DNA hairpin Proceedings of the National Academy of Sciences of the United States of America. 98: 5584-5589. PMID 11320222 DOI: 10.1073/Pnas.101523498  0.334
2001 Isalan M, Patel SD, Balasubramanian S, Choo Y. Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation Biochemistry. 40: 830-836. PMID 11170401 DOI: 10.1021/Bi001728V  0.473
2001 Osborne MA, Barnes CL, Balasubramanian S, Klenerman D. Probing DNA Surface Attachment and Local Environment Using Single Molecule Spectroscopy Journal of Physical Chemistry B. 105: 3120-3126. DOI: 10.1021/Jp0038660  0.351
2000 Liu X, Balasubramanian S. Strategies for the synthesis of fluorescently labelled PNA. Tetrahedron Letters. 41: 6153-6156. PMID 18259605 DOI: 10.1016/S0040-4039(00)00996-5  0.576
2000 Osborne MA, Furey WS, Klenerman D, Balasubramanian S. Single-molecule analysis of DNA immobilized on microspheres. Analytical Chemistry. 72: 3678-81. PMID 10952560 DOI: 10.1021/Ac000129R  0.318
1999 Lee HB, Balasubramanian S. Studies on a Dithiane-Protected Benzoin Photolabile Safety Catch Linker for Solid-Phase Synthesis. Journal of Organic Chemistry. 64: 3454-3460. PMID 11674652 DOI: 10.1021/Jo994991E  0.312
1999 Harrison JG, Liu X, Balasubramanian S. Screening for oligonucleotide binding affinity by a convenient fluorescence competition assay. Nucleic Acids Research. 27: e14. PMID 10446257 DOI: 10.1093/Nar/27.17.E14-I  0.632
1999 Harrison JG, Frier C, Laurant R, Dennis R, Raney KD, Balasubramanian S. Inhibition of human telomerase by PNA-cationic peptide conjugates. Bioorganic & Medicinal Chemistry Letters. 9: 1273-8. PMID 10340613 DOI: 10.1016/S0960-894X(99)00170-5  0.721
1997 Cheung YW, Abell C, Balasubramanian S. A Combinatorial Approach to Identifying Protein Tyrosine Phosphatase Substrates from a Phosphotyrosine Peptide Library Journal of the American Chemical Society. 119: 9568-9569. DOI: 10.1021/Ja971825K  0.643
1997 Todd MH, Balasubramanian S, Abell C. Studies on the synthesis, characterisation and reactivity of aromatic diboronic acids Tetrahedron Letters. 38: 6781-6784. DOI: 10.1016/S0040-4039(97)01552-9  0.61
1997 Arumugam V, Routledge A, Abell C, Balasubramanian S. Synthesis of 2-oxindole derivatives via the intramolecular Heck reaction on solid support Tetrahedron Letters. 38: 6473-6476. DOI: 10.1016/S0040-4039(97)01481-0  0.757
1997 Routledge A, Abell C, Balasubramanian S. The use of a dithiane protected benzoin photolabile safety catch linker for solid-phase synthesis Tetrahedron Letters. 38: 1227-1230. DOI: 10.1016/S0040-4039(96)02478-1  0.681
1995 Bornemann S, Balasubramanian S, Coggins JR, Abell C, Lowe DJ, Thorneley RN. Escherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved. The Biochemical Journal. 305: 707-10. PMID 7848266 DOI: 10.1042/Bj3050707  0.441
1995 Balasubramanian S, Coggins JR, Abell C. Observation of a secondary tritium isotope effect in the chorismate synthase reaction. Biochemistry. 34: 341-8. PMID 7819217 DOI: 10.1021/Bi00001A042  0.442
1995 Carr RT, Balasubramanian S, Hawkins PC, Benkovic SJ. Mechanism of metal-independent hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase. Biochemistry. 34: 7525-32. PMID 7779797 DOI: 10.1021/Bi00022A028  0.412
1995 Bornemann S, Ramjee MK, Balasubramanian S, Abell C, Coggins JR, Lowe DJ, Thorneley RN. Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate. The Journal of Biological Chemistry. 270: 22811-5. PMID 7559411 DOI: 10.1074/Jbc.270.39.22811  0.494
1994 Balasubramanian S, Carr RT, Bender CJ, Peisach J, Benkovic SJ. Identification of metal ligands in Cu(II)-inhibited Chromobacterium violaceum phenylalanine hydroxylase by electron spin echo envelope modulation analysis of histidine to serine mutations. Biochemistry. 33: 8532-7. PMID 8031788 DOI: 10.1021/Bi00194A019  0.432
1994 Peliska JA, Balasubramanian S, Giedroc DP, Benkovic SJ. Recombinant HIV-1 nucleocapsid protein accelerates HIV-1 reverse transcriptase catalyzed DNA strand transfer reactions and modulates RNase H activity. Biochemistry. 33: 13817-23. PMID 7524664 DOI: 10.1021/Bi00250A036  0.482
1993 Balasubramanian S, Carr RT, Bender CJ, Peisach J, Benkovic SJ. Histidines 138 and 143 are copper binding ligands in Chromobacterium violaceum phenylalanine hydroxylase. Advances in Experimental Medicine and Biology. 338: 67-70. PMID 8304204 DOI: 10.1007/978-1-4615-2960-6_13  0.42
1992 Ramjee MN, Balasubramanian S, Abell C, Coggins JR, Davies GM, Hawkes TR, Lowe DJ, Thorneley RNF. Reaction of (6R)-6-fluoroEPSP with recombinant Escherichia coli chorismate synthase generates a stable flavin mononucleotide semiquinone radical Journal of the American Chemical Society. 114: 3151-3153. DOI: 10.1021/Ja00034A079  0.431
1991 Balasubramanian S, Davies GM, Coggins JR, Abell C. Inhibition of chorismate synthase by (6R)- and (6S)-6-fluoro-5-enolpyruvylshikimate 3-phosphate Journal of the American Chemical Society. 113: 8945-8946. DOI: 10.1021/Ja00023A051  0.426
1991 Balasubramanian S, Abell C. The synthesis of (6R)-[6-2H]- and (6S)-[6-2H]5-enolpyruvylshikimate-3-phosphate Tetrahedron Letters. 32: 963-966. DOI: 10.1016/S0040-4039(00)92131-2  0.439
1990 Balasubramanian S, Abell C, Coggins JR. Observation of an isotope effect in the chorismate synthase reaction Journal of the American Chemical Society. 112: 8581-8583. DOI: 10.1021/Ja00179A052  0.417
Show low-probability matches.