| Year |
Citation |
Score |
| 2015 |
Shalev M, Rozenberg H, Smolkin B, Nasereddin A, Kopelyanskiy D, Belakhov V, Schrepfer T, Schacht J, Jaffe CL, Adir N, Baasov T. Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics. Nucleic Acids Research. 43: 8601-13. PMID 26264664 DOI: 10.1093/Nar/Gkv821 |
0.579 |
|
| 2015 |
Baasov T, Fridman M, Werz DB. Carbohydrates: Special issue in honor of the 2014 wolf prize laureate in chemistry, professor Chi-Huey Wong Israel Journal of Chemistry. 55: 253. DOI: 10.1002/Ijch.201510003 |
0.418 |
|
| 2014 |
Baasov T, Fridman M. Foreword-The 17th European Carbohydrate Symposium-EuroCarb17. Carbohydrate Research. 389: 1. PMID 24726717 DOI: 10.1016/J.Carres.2014.03.013 |
0.405 |
|
| 2014 |
Gunn G, Dai Y, Du M, Belakhov V, Kandasamy J, Schoeb TR, Baasov T, Bedwell DM, Keeling KM. Long-term nonsense suppression therapy moderates MPS I-H disease progression. Molecular Genetics and Metabolism. 111: 374-81. PMID 24411223 DOI: 10.1016/J.Ymgme.2013.12.007 |
0.646 |
|
| 2014 |
Gunn GG, Dai Y, Du M, Beklakhov V, Kandasamy J, Schoeb TR, Baasov T, Bedwell DM, Keeling KM. Long-term nonsense suppression therapy with NB84 moderates MPS IH disease progression Molecular Genetics and Metabolism. 111: S50. DOI: 10.1016/J.Ymgme.2013.12.106 |
0.599 |
|
| 2013 |
Shalev M, Kondo J, Kopelyanskiy D, Jaffe CL, Adir N, Baasov T. Identification of the molecular attributes required for aminoglycoside activity against Leishmania. Proceedings of the National Academy of Sciences of the United States of America. 110: 13333-8. PMID 23898171 DOI: 10.1073/pnas.1307365110 |
0.572 |
|
| 2013 |
Keeling KM, Wang D, Dai Y, Murugesan S, Chenna B, Clark J, Belakhov V, Kandasamy J, Velu SE, Baasov T, Bedwell DM. Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression. Plos One. 8: e60478. PMID 23593225 DOI: 10.1371/Journal.Pone.0060478 |
0.633 |
|
| 2013 |
Shalev M, Kandasamy J, Skalka N, Belakhov V, Rosin-Arbesfeld R, Baasov T. Development of generic immunoassay for the detection of a series of aminoglycosides with 6'-OH group for the treatment of genetic diseases in biological samples. Journal of Pharmaceutical and Biomedical Analysis. 75: 33-40. PMID 23312382 DOI: 10.1016/j.jpba.2012.11.014 |
0.616 |
|
| 2012 |
Kandasamy J, Atia-Glikin D, Shulman E, Shapira K, Shavit M, Belakhov V, Baasov T. Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: A strategy for treatment of genetic diseases caused by nonsense mutations Journal of Medicinal Chemistry. 55: 10630-10643. PMID 23148581 DOI: 10.1021/jm3012992 |
0.639 |
|
| 2012 |
Wang D, Belakhov V, Kandasamy J, Baasov T, Li SC, Li YT, Bedwell DM, Keeling KM. The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse. Molecular Genetics and Metabolism. 105: 116-25. PMID 22056610 DOI: 10.1016/J.Ymgme.2011.10.005 |
0.647 |
|
| 2011 |
Kandasamy J, Atia-Glikin D, Belakhov V, Baasov T. Repairing faulty genes by aminoglycosides: Identification of new pharmacophore with enhanced suppression of disease-causing nonsense mutations Medchemcomm. 2: 165. DOI: 10.1039/C0MD00195C |
0.615 |
|
| 2010 |
Pokrovskaya V, Nudelman I, Kandasamy J, Baasov T. Aminoglycosides redesign strategies for improved antibiotics and compounds for treatment of human genetic diseases. Methods in Enzymology. 478: 437-62. PMID 20816493 DOI: 10.1016/S0076-6879(10)78021-6 |
0.65 |
|
| 2008 |
Hainrichson M, Nudelman I, Baasov T. Designer aminoglycosides: the race to develop improved antibiotics and compounds for the treatment of human genetic diseases. Organic & Biomolecular Chemistry. 6: 227-39. PMID 18174989 DOI: 10.1039/b712690p |
0.307 |
|
| 2005 |
Vainer R, Belakhov V, Rabkin E, Baasov T, Adir N. Crystal structures of Escherichia coli KDO8P synthase complexes reveal the source of catalytic irreversibility. Journal of Molecular Biology. 351: 641-52. PMID 16023668 DOI: 10.1016/j.jmb.2005.06.021 |
0.533 |
|
| 2005 |
Hainrichson M, Pokrovskaya V, Shallom-Shezifi D, Fridman M, Belakhov V, Shachar D, Yaron S, Baasov T. Branched aminoglycosides: biochemical studies and antibacterial activity of neomycin B derivatives. Bioorganic & Medicinal Chemistry. 13: 5797-807. PMID 15993084 DOI: 10.1016/J.Bmc.2005.05.058 |
0.513 |
|
| 2005 |
Fridman M, Belakhov V, Lee LV, Liang FS, Wong CH, Baasov T. Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor. Angewandte Chemie (International Ed. in English). 44: 447-52. PMID 15624157 DOI: 10.1002/Anie.200462003 |
0.488 |
|
| 2004 |
Shulami S, Furdui C, Adir N, Shoham Y, Anderson KS, Baasov T. A reciprocal single mutation affects the metal requirement of 3-deoxy-D-manno-2-octulosonate-8-phosphate (KDO8P) synthases from aquifex pyrophilus and Escherichia coli Journal of Biological Chemistry. 279: 45110-45120. PMID 15308670 DOI: 10.1074/Jbc.M404561200 |
0.521 |
|
| 2003 |
Fridman M, Belakhov V, Yaron S, Baasov T. A new class of branched aminoglycosides: pseudo-pentasaccharide derivatives of neomycin B. Organic Letters. 5: 3575-8. PMID 14507176 DOI: 10.1021/Ol035213I |
0.47 |
|
| 2002 |
Fridman M, Solomon D, Yogev S, Baasov T. One-pot synthesis of glucosamine oligosaccharides. Organic Letters. 4: 281-3. PMID 11796070 DOI: 10.1021/Ol017054D |
0.449 |
|
| 2002 |
Vainer R, Adir N, Rabkin E, Belakhov V, Baasov T. Determination of the structure of KDO8P synthase with the natural substrate A5P, Z-FPEP and E-FPEP Acta Crystallographica Section a Foundations of Crystallography. 58: c115-c115. DOI: 10.1107/S0108767302089626 |
0.491 |
|
| 2001 |
Solomon D, Fridman M, Zhang J, Baasov T. A synthetic pentasaccharide with GTPase activity Organic Letters. 3: 4311-4314. PMID 11784205 DOI: 10.1021/Ol010257H |
0.472 |
|
| 2001 |
Asojo O, Friedman J, Adir N, Belakhov V, Shoham Y, Baasov T. Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor Biochemistry. 40: 6326-6334. PMID 11371194 DOI: 10.1021/bi010339d |
0.521 |
|
| 1989 |
Baasov T, Knowles JR. Is the first enzyme of the shikimate pathway, 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (tyrosine sensitive), a copper metalloenzyme? Journal of Bacteriology. 171: 6155-60. PMID 2572582 |
0.439 |
|
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