Year |
Citation |
Score |
2024 |
Carnie CJ, Acampora AC, Bader AS, Erdenebat C, Zhao S, Bitensky E, van den Heuvel D, Parnas A, Gupta V, D'Alessandro G, Sczaniecka-Clift M, Weickert P, Aygenli F, Götz MJ, Cordes J, ... ... Jackson SP, et al. Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB. Nature Cell Biology. PMID 38600235 DOI: 10.1038/s41556-024-01391-1 |
0.466 |
|
2023 |
D'Alessandro G, Morales-Juarez DA, Richards SL, Nitiss KC, Serrano-Benitez A, Wang J, Thomas JC, Gupta V, Voigt A, Belotserkovskaya R, Goh CG, Bowden AR, Galanty Y, Beli P, Nitiss JL, ... ... Jackson SP, et al. RAD54L2 counters TOP2-DNA adducts to promote genome stability. Science Advances. 9: eadl2108. PMID 38055822 DOI: 10.1126/sciadv.adl2108 |
0.5 |
|
2023 |
Serrano-Benitez A, Wells SE, Drummond-Clarke L, Russo LC, Thomas JC, Leal GA, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, ... Jackson SP, et al. Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity. The Embo Journal. e113190. PMID 37492888 DOI: 10.15252/embj.2022113190 |
0.438 |
|
2023 |
Awwad SW, Serrano-Benitez A, Thomas JC, Gupta V, Jackson SP. Revolutionizing DNA repair research and cancer therapy with CRISPR-Cas screens. Nature Reviews. Molecular Cell Biology. PMID 36781955 DOI: 10.1038/s41580-022-00571-x |
0.387 |
|
2022 |
Vincendeau E, Wei W, Zhang X, Planchais C, Yu W, Lenden-Hasse H, Cokelaer T, Pipoli da Fonseca J, Mouquet H, Adams DJ, Alt FW, Jackson SP, Balmus G, Lescale C, Deriano L. SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination. Nature Communications. 13: 3707. PMID 35764636 DOI: 10.1038/s41467-022-31287-3 |
0.317 |
|
2022 |
Cabello-Lobato MJ, Jenner M, Cisneros-Aguirre M, Brüninghoff K, Sandy Z, da Costa IC, Jowitt TA, Loch CM, Jackson SP, Wu Q, Mootz HD, Stark JM, Cliff MJ, Schmidt CK. Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. Nucleic Acids Research. PMID 35420136 DOI: 10.1093/nar/gkac237 |
0.46 |
|
2021 |
Lloyd RL, Urban V, Muñoz-Martínez F, Ayestaran I, Thomas JC, de Renty C, O'Connor MJ, Forment JV, Galanty Y, Jackson SP. Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress. Nucleic Acids Research. PMID 34329458 DOI: 10.1093/nar/gkab628 |
0.341 |
|
2021 |
Pilger D, Seymour LW, Jackson SP. Interfaces between cellular responses to DNA damage and cancer immunotherapy. Genes & Development. PMID 33888558 DOI: 10.1101/gad.348314.121 |
0.339 |
|
2020 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, ... ... Jackson SP, et al. Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics. PMID 32918070 DOI: 10.1038/S41588-020-00711-Z |
0.668 |
|
2020 |
Ochi T, Quarantotti V, Lin H, Jullien J, Rosa E Silva I, Boselli F, Barnabas DD, Johnson CM, McLaughlin SH, Freund SMV, Blackford AN, Kimata Y, Goldstein RE, Jackson SP, Blundell TL, et al. CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions. Structure (London, England : 1993). PMID 32375023 DOI: 10.1016/J.Str.2020.04.010 |
0.661 |
|
2020 |
Belotserkovskaya R, Raga Gil E, Lawrence N, Butler R, Clifford G, Wilson MD, Jackson SP. PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1. Nature Communications. 11: 819. PMID 32041954 DOI: 10.1038/S41467-020-14563-Y |
0.379 |
|
2019 |
Salguero I, Belotserkovskaya R, Coates J, Sczaniecka-Clift M, Demir M, Jhujh S, Wilson MD, Jackson SP. MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance. Nature Communications. 10: 5191. PMID 31729360 DOI: 10.1038/s41467-019-12929-5 |
0.529 |
|
2019 |
Cornwell MJ, Thomson GJ, Coates J, Belotserkovskaya R, Waddell ID, Jackson SP, Galanty Y. Small Molecule Inhibition of UBE2T/FANCL-mediated Ubiquitylation in the Fanconi Anemia Pathway. Acs Chemical Biology. PMID 31525021 DOI: 10.1021/acschembio.9b00570 |
0.317 |
|
2019 |
Kucab JE, Zou X, Morganella S, Joel M, Nanda AS, Nagy E, Gomez C, Degasperi A, Harris R, Jackson SP, Arlt VM, Phillips DH, Nik-Zainal S. A Compendium of Mutational Signatures of Environmental Agents. Cell. PMID 30982602 DOI: 10.1016/J.Cell.2019.03.001 |
0.314 |
|
2019 |
Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, ... ... Jackson SP, et al. ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks. Nature Communications. 10: 87. PMID 30622252 DOI: 10.1038/S41467-018-07729-2 |
0.466 |
|
2018 |
Allen F, Crepaldi L, Alsinet C, Strong AJ, Kleshchevnikov V, De Angeli P, Páleníková P, Khodak A, Kiselev V, Kosicki M, Bassett AR, Harding H, Galanty Y, Muñoz-Martínez F, Metzakopian E, ... Jackson SP, et al. Predicting the mutations generated by repair of Cas9-induced double-strand breaks. Nature Biotechnology. PMID 30480667 DOI: 10.1038/nbt.4317 |
0.311 |
|
2018 |
Millan-Zambrano G, Santos-Rosa H, Puddu F, Robson SC, Jackson SP, Kouzarides T. Phosphorylation of Histone H4T80 Triggers DNA Damage Checkpoint Recovery. Molecular Cell. 72: 625-635.e4. PMID 30454561 DOI: 10.1016/J.Molcel.2018.09.023 |
0.463 |
|
2018 |
Dev H, Chiang TW, Lescale C, de Krijger I, Martin AG, Pilger D, Coates J, Sczaniecka-Clift M, Wei W, Ostermaier M, Herzog M, Lam J, Shea A, Demir M, Wu Q, ... ... Jackson SP, et al. Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells. Nature Cell Biology. PMID 30022119 DOI: 10.1038/s41556-018-0140-1 |
0.339 |
|
2018 |
Velimezi G, Robinson-Garcia L, Muñoz-Martínez F, Wiegant WW, Ferreira da Silva J, Owusu M, Moder M, Wiedner M, Rosenthal SB, Fisch KM, Moffat J, Menche J, van Attikum H, Jackson SP, Loizou JI. Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48. Nature Communications. 9: 2280. PMID 29891926 DOI: 10.1038/S41467-018-04649-Z |
0.425 |
|
2018 |
Herzog M, Puddu F, Coates J, Geisler N, Forment JV, Jackson SP. Detection of functional protein domains by unbiased genome-wide forward genetic screening. Scientific Reports. 8: 6161. PMID 29670134 DOI: 10.1038/S41598-018-24400-4 |
0.31 |
|
2017 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, ... ... Jackson SP, et al. Erratum: PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics. 49: 1558. PMID 28951624 DOI: 10.1038/Ng1017-1558B |
0.658 |
|
2017 |
Blackford AN, Jackson SP. ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response. Molecular Cell. 66: 801-817. PMID 28622525 DOI: 10.1016/j.molcel.2017.05.015 |
0.782 |
|
2017 |
Chanut P, Britton S, Coates J, Jackson SP, Calsou P. Corrigendum: Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks. Nature Communications. 8: 15917. PMID 28607502 DOI: 10.1038/ncomms15917 |
0.4 |
|
2017 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, MacArthur IC, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, de Stanchina E, Gönen M, ... ... Jackson SP, et al. PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics. PMID 28504702 DOI: 10.1038/Ng.3866 |
0.746 |
|
2017 |
Puddu F, Salguero I, Herzog M, Geisler NJ, Costanzo V, Jackson SP. Chromatin determinants impart camptothecin sensitivity. Embo Reports. PMID 28389464 DOI: 10.15252/Embr.201643560 |
0.375 |
|
2017 |
Henssen AG, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford AN, Mason CE, Stanchina Ed, Gönen M, Emde A, ... ... Jackson SP, et al. Abstract 4888: Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors Cancer Research. 77: 4888-4888. DOI: 10.1158/1538-7445.Am2017-4888 |
0.74 |
|
2017 |
Henssen A, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, Rodríguez-Fos E, Gonzalez S, Puiggròs M, Blackford A, Mason C, Stanchina Ed, Gönen M, Emde A, ... ... Jackson S, et al. Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors Klinische Padiatrie. 229. DOI: 10.1055/S-0037-1602202 |
0.742 |
|
2016 |
Brown JS, O'Carrigan B, Jackson SP, Yap TA. Targeting DNA Repair in Cancer: Beyond PARP Inhibitors. Cancer Discovery. PMID 28003236 DOI: 10.1158/2159-8290.CD-16-0860 |
0.483 |
|
2016 |
Balmus G, Barros AC, Wijnhoven PW, Lescale C, Hasse HL, Boroviak K, le Sage C, Doe B, Speak AO, Galli A, Jacobsen M, Deriano L, Adams DJ, Blackford AN, Jackson SP. Synthetic lethality between PAXX and XLF in mammalian development. Genes & Development. 30: 2152-2157. PMID 27798842 DOI: 10.1101/Gad.290510.116 |
0.673 |
|
2016 |
Chang HH, Watanabe G, Gerodimos CA, Ochi T, Blundell TL, Jackson SP, Lieber MR. Different DNA End Configurations Dictate Which NHEJ Components are Most Important for Joining Efficiency. The Journal of Biological Chemistry. PMID 27703001 DOI: 10.1074/Jbc.M116.752329 |
0.508 |
|
2016 |
Chanut P, Britton S, Coates J, Jackson SP, Calsou P. Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks. Nature Communications. 7: 12889. PMID 27641979 DOI: 10.1038/ncomms12889 |
0.495 |
|
2016 |
Lescale C, Lenden Hasse H, Blackford AN, Balmus G, Bianchi JJ, Yu W, Bacoccina L, Jarade A, Clouin C, Sivapalan R, Reina-San-Martin B, Jackson SP, Deriano L. Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination. Cell Reports. PMID 27601299 DOI: 10.1016/j.celrep.2016.08.069 |
0.767 |
|
2016 |
Yu S, Evans KE, van Eijk P, Bennett M, Webster RM, Leadbitter M, Teng Y, Waters R, Jackson SP, Reed SH. Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin. Genome Research. PMID 27470111 DOI: 10.1101/gr.209106.116 |
0.356 |
|
2016 |
Cobb AM, Larrieu D, Warren DT, Liu Y, Srivastava S, Smith AJ, Bowater RP, Jackson SP, Shanahan CM. Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradient. Aging Cell. PMID 27464478 DOI: 10.1111/acel.12506 |
0.334 |
|
2016 |
Agarwal P, Jackson SP. G9a inhibition potentiates anti-tumor activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status. Cancer Letters. PMID 27431310 DOI: 10.1016/j.canlet.2016.07.009 |
0.415 |
|
2016 |
Jackson SP, Helleday T. DNA REPAIR. Drugging DNA repair. Science (New York, N.Y.). 352: 1178-9. PMID 27257245 DOI: 10.1126/science.aab0958 |
0.451 |
|
2016 |
Chiang TW, le Sage C, Larrieu D, Demir M, Jackson SP. CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing. Scientific Reports. 6: 24356. PMID 27079678 DOI: 10.1038/srep24356 |
0.31 |
|
2015 |
Harley ME, Murina O, Leitch A, Higgs MR, Bicknell LS, Yigit G, Blackford AN, Zlatanou A, Mackenzie KJ, Reddy K, Halachev M, McGlasson S, Reijns MA, Fluteau A, Martin CA, ... ... Jackson SP, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nature Genetics. PMID 26595769 DOI: 10.1038/Ng.3451 |
0.775 |
|
2015 |
Silva AP, Ryan DP, Galanty Y, Low JK, Vandevenne M, Jackson SP, Mackay JP. The N-terminal region of CHD4 is essential for activity and contains a HMG-box-like-domain that can bind poly(ADP-ribose). The Journal of Biological Chemistry. PMID 26565020 DOI: 10.1074/Jbc.M115.683227 |
0.417 |
|
2015 |
Gill SJ, Travers J, Pshenichnaya I, Kogera FA, Barthorpe S, Mironenko T, Richardson L, Benes CH, Stratton MR, McDermott U, Jackson SP, Garnett MJ. Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's Sarcoma. Plos One. 10: e0140988. PMID 26505995 DOI: 10.1371/journal.pone.0140988 |
0.424 |
|
2015 |
Schmidt CK, Galanty Y, Sczaniecka-Clift M, Coates J, Jhujh S, Demir M, Cornwell M, Beli P, Jackson SP. Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair. Nature Cell Biology. 17: 1458-70. PMID 26502057 DOI: 10.1038/ncb3260 |
0.402 |
|
2015 |
Wijnhoven P, Konietzny R, Blackford AN, Travers J, Kessler BM, Nishi R, Jackson SP. USP4 Auto-Deubiquitylation Promotes Homologous Recombination. Molecular Cell. 60: 362-73. PMID 26455393 DOI: 10.1016/j.molcel.2015.09.019 |
0.798 |
|
2015 |
Yuan Y, Britton S, Delteil C, Coates J, Jackson SP, Barboule N, Frit P, Calsou P. Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein. Nucleic Acids Research. PMID 26350212 DOI: 10.1093/nar/gkv894 |
0.501 |
|
2015 |
Forment JV, Jackson SP, Pellegrini L. When two is not enough: a CtIP tetramer is required for DNA repair by Homologous Recombination. Nucleus (Austin, Tex.). 0. PMID 26305173 DOI: 10.1080/19491034.2015.1086050 |
0.516 |
|
2015 |
Beli P, Jackson SP. Ubiquitin regulates dissociation of DNA repair factors from chromatin. Oncotarget. 6: 14727-8. PMID 26142703 |
0.476 |
|
2015 |
Brown JS, Lukashchuk N, Sczaniecka-Clift M, Britton S, le Sage C, Calsou P, Beli P, Galanty Y, Jackson SP. Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites. Cell Reports. 11: 704-14. PMID 25921528 DOI: 10.1016/j.celrep.2015.03.058 |
0.498 |
|
2015 |
Puddu F, Oelschlaegel T, Guerini I, Geisler NJ, Niu H, Herzog M, Salguero I, Ochoa-Montaño B, Viré E, Sung P, Adams DJ, Keane TM, Jackson SP. Synthetic viability genomic screening defines Sae2 function in DNA repair. The Embo Journal. 34: 1509-22. PMID 25899817 DOI: 10.15252/Embj.201590973 |
0.517 |
|
2015 |
Brown JS, Jackson SP. Ubiquitylation, neddylation and the DNA damage response. Open Biology. 5: 150018. PMID 25833379 DOI: 10.1098/rsob.150018 |
0.512 |
|
2015 |
Blackford AN, Nieminuszczy J, Schwab RA, Galanty Y, Jackson SP, Niedzwiedz W. TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation. Molecular Cell. 57: 1133-41. PMID 25794620 DOI: 10.1016/j.molcel.2015.02.012 |
0.753 |
|
2015 |
Chen W, Kong J, Qin C, Yu S, Tan J, Chen YR, Wu C, Wang H, Shi Y, Li C, Li B, Zhang P, Wang Y, Lai T, Yu Z, ... ... Jackson S, et al. Requirement of CHROMOMETHYLASE3 for somatic inheritance of the spontaneous tomato epimutation Colourless non-ripening. Scientific Reports. 5: 9192. PMID 25778911 DOI: 10.1038/Srep09192 |
0.321 |
|
2015 |
Ochi T, Blackford AN, Coates J, Jhujh S, Mehmood S, Tamura N, Travers J, Wu Q, Draviam VM, Robinson CV, Blundell TL, Jackson SP. DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science (New York, N.Y.). 347: 185-8. PMID 25574025 DOI: 10.1126/Science.1261971 |
0.792 |
|
2014 |
Nishi R, Wijnhoven P, le Sage C, Tjeertes J, Galanty Y, Forment JV, Clague MJ, Urbé S, Jackson SP. Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity. Nature Cell Biology. 16: 1016-26, 1-8. PMID 25194926 DOI: 10.1038/ncb3028 |
0.47 |
|
2014 |
Blasius M, Wagner SA, Choudhary C, Bartek J, Jackson SP. A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response. Genes & Development. 28: 1977-82. PMID 25189701 DOI: 10.1101/gad.246272.114 |
0.48 |
|
2014 |
Polato F, Callen E, Wong N, Faryabi R, Bunting S, Chen HT, Kozak M, Kruhlak MJ, Reczek CR, Lee WH, Ludwig T, Baer R, Feigenbaum L, Jackson S, Nussenzweig A. CtIP-mediated resection is essential for viability and can operate independently of BRCA1. The Journal of Experimental Medicine. 211: 1027-36. PMID 24842372 DOI: 10.1084/Jem.20131939 |
0.452 |
|
2014 |
Belotserkovskaya R, Jackson SP. Keeping 53BP1 out of focus in mitosis. Cell Research. 24: 781-2. PMID 24810302 DOI: 10.1038/cr.2014.62 |
0.419 |
|
2014 |
Knobel PA, Belotserkovskaya R, Galanty Y, Schmidt CK, Jackson SP, Stracker TH. USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism. Molecular and Cellular Biology. 34: 2062-74. PMID 24687851 DOI: 10.1128/MCB.00197-14 |
0.449 |
|
2014 |
Aymard F, Bugler B, Schmidt CK, Guillou E, Caron P, Briois S, Iacovoni JS, Daburon V, Miller KM, Jackson SP, Legube G. Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks. Nature Structural & Molecular Biology. 21: 366-74. PMID 24658350 DOI: 10.1038/nsmb.2796 |
0.631 |
|
2013 |
Britton S, Coates J, Jackson SP. A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair. The Journal of Cell Biology. 202: 579-95. PMID 23897892 DOI: 10.1083/jcb.201303073 |
0.396 |
|
2013 |
Jacq X, Kemp M, Martin NM, Jackson SP. Deubiquitylating enzymes and DNA damage response pathways. Cell Biochemistry and Biophysics. 67: 25-43. PMID 23712866 DOI: 10.1007/s12013-013-9635-3 |
0.39 |
|
2013 |
Schmidt CK, Jackson SP. On your mark, get SET(D2), go! H3K36me3 primes DNA mismatch repair. Cell. 153: 513-5. PMID 23622237 DOI: 10.1016/j.cell.2013.04.018 |
0.397 |
|
2013 |
Jackson SP, Durocher D. Regulation of DNA damage responses by ubiquitin and SUMO. Molecular Cell. 49: 795-807. PMID 23416108 DOI: 10.1016/J.Molcel.2013.01.017 |
0.69 |
|
2013 |
Moumen A, Magill C, Dry KL, Jackson SP. ATM-dependent phosphorylation of heterogeneous nuclear ribonucleoprotein K promotes p53 transcriptional activation in response to DNA damage. Cell Cycle (Georgetown, Tex.). 12: 698-704. PMID 23343766 DOI: 10.4161/cc.23592 |
0.348 |
|
2013 |
Muñoz-Galván S, López-Saavedra A, Jackson SP, Huertas P, Cortés-Ledesma F, Aguilera A. Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination. Nucleic Acids Research. 41: 1669-83. PMID 23254329 DOI: 10.1093/nar/gks1274 |
0.501 |
|
2013 |
Chen WT, Alpert A, Leiter C, Gong F, Jackson SP, Miller KM. Systematic identification of functional residues in mammalian histone H2AX. Molecular and Cellular Biology. 33: 111-26. PMID 23109425 DOI: 10.1128/MCB.01024-12 |
0.63 |
|
2012 |
Forment JV, Walker RV, Jackson SP. A high-throughput, flow cytometry-based method to quantify DNA-end resection in mammalian cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 922-8. PMID 22893507 DOI: 10.1002/cyto.a.22155 |
0.506 |
|
2012 |
Schiller CB, Lammens K, Guerini I, Coordes B, Feldmann H, Schlauderer F, Möckel C, Schele A, Strässer K, Jackson SP, Hopfner KP. Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling. Nature Structural & Molecular Biology. 19: 693-700. PMID 22705791 DOI: 10.1038/nsmb.2323 |
0.466 |
|
2012 |
Galanty Y, Belotserkovskaya R, Coates J, Jackson SP. RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair. Genes & Development. 26: 1179-95. PMID 22661229 DOI: 10.1101/gad.188284.112 |
0.433 |
|
2012 |
Falck J, Forment JV, Coates J, Mistrik M, Lukas J, Bartek J, Jackson SP. CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination. Embo Reports. 13: 561-8. PMID 22565321 DOI: 10.1038/Embor.2012.58 |
0.461 |
|
2012 |
Chapman JR, Sossick AJ, Boulton SJ, Jackson SP. BRCA1-associated exclusion of 53BP1 from DNA: Damage sites underlies temporal control of DNA repair Journal of Cell Science. 125: 3529-3534. PMID 22553214 DOI: 10.1242/jcs.105353 |
0.708 |
|
2012 |
Miller KM, Jackson SP. Histone marks: repairing DNA breaks within the context of chromatin. Biochemical Society Transactions. 40: 370-6. PMID 22435814 DOI: 10.1042/BST20110747 |
0.676 |
|
2012 |
Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C. Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response. Molecular Cell. 46: 212-25. PMID 22424773 DOI: 10.1016/J.Molcel.2012.01.026 |
0.501 |
|
2012 |
Polo SE, Blackford AN, Chapman JR, Baskcomb L, Gravel S, Rusch A, Thomas A, Blundred R, Smith P, Kzhyshkowska J, Dobner T, Taylor AM, Turnell AS, Stewart GS, Grand RJ, ... Jackson SP, et al. Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair. Molecular Cell. 45: 505-16. PMID 22365830 DOI: 10.1016/j.molcel.2011.12.035 |
0.816 |
|
2012 |
Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nature Chemical Biology. 8: 301-10. PMID 22306580 DOI: 10.1038/Nchembio.780 |
0.626 |
|
2011 |
Forment JV, Blasius M, Guerini I, Jackson SP. Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation. Plos One. 6: e23517. PMID 21858151 DOI: 10.1371/journal.pone.0023517 |
0.491 |
|
2011 |
Blasius M, Forment JV, Thakkar N, Wagner SA, Choudhary C, Jackson SP. A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1. Genome Biology. 12: R78. PMID 21851590 DOI: 10.1186/Gb-2011-12-8-R78 |
0.385 |
|
2011 |
Flott S, Kwon Y, Pigli YZ, Rice PA, Sung P, Jackson SP. Regulation of Rad51 function by phosphorylation. Embo Reports. 12: 833-9. PMID 21738226 DOI: 10.1038/Embor.2011.127 |
0.53 |
|
2011 |
Harrigan JA, Belotserkovskaya R, Coates J, Dimitrova DS, Polo SE, Bradshaw CR, Fraser P, Jackson SP. Replication stress induces 53BP1-containing OPT domains in G1 cells Journal of Cell Biology. 193: 97-108. PMID 21444690 DOI: 10.1083/jcb.201011083 |
0.45 |
|
2011 |
Giunta S, Jackson SP. Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events. Cell Cycle (Georgetown, Tex.). 10: 1215-21. PMID 21412056 DOI: 10.4161/cc.10.8.15334 |
0.522 |
|
2011 |
Polo SE, Jackson SP. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes & Development. 25: 409-33. PMID 21363960 DOI: 10.1101/gad.2021311 |
0.477 |
|
2010 |
Kaidi A, Weinert BT, Choudhary C, Jackson SP. Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science (New York, N.Y.). 329: 1348-53. PMID 20829486 DOI: 10.1126/Science.1192049 |
0.523 |
|
2010 |
Miller KM, Tjeertes JV, Coates J, Legube G, Polo SE, Britton S, Jackson SP. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nature Structural & Molecular Biology. 17: 1144-51. PMID 20802485 DOI: 10.1038/nsmb.1899 |
0.655 |
|
2010 |
Polo SE, Kaidi A, Baskcomb L, Galanty Y, Jackson SP. Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4. The Embo Journal. 29: 3130-9. PMID 20693977 DOI: 10.1038/emboj.2010.188 |
0.535 |
|
2010 |
Giunta S, Belotserkovskaya R, Jackson SP. DNA damage signaling in response to double-strand breaks during mitosis. The Journal of Cell Biology. 190: 197-207. PMID 20660628 DOI: 10.1083/jcb.200911156 |
0.436 |
|
2010 |
Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science (New York, N.Y.). 329: 78-82. PMID 20595612 DOI: 10.1126/science.1187945 |
0.488 |
|
2009 |
Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature. 462: 935-9. PMID 20016603 DOI: 10.1038/nature08657 |
0.681 |
|
2009 |
Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature. 461: 1071-8. PMID 19847258 DOI: 10.1038/nature08467 |
0.41 |
|
2009 |
Lloyd J, Chapman JR, Clapperton JA, Haire LF, Hartsuiker E, Li J, Carr AM, Jackson SP, Smerdon SJ. A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage Cell. 139: 100-111. PMID 19804756 DOI: 10.1016/j.cell.2009.07.043 |
0.484 |
|
2009 |
Ahel D, Horejsí Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M, West SC, Jackson SP, Owen-Hughes T, Boulton SJ. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science (New York, N.Y.). 325: 1240-3. PMID 19661379 DOI: 10.1126/Science.1177321 |
0.817 |
|
2009 |
Jackson SP. The DNA-damage response: new molecular insights and new approaches to cancer therapy. Biochemical Society Transactions. 37: 483-94. PMID 19442242 DOI: 10.1042/BST0370483 |
0.475 |
|
2009 |
Tjeertes JV, Miller KM, Jackson SP. Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. The Embo Journal. 28: 1878-89. PMID 19407812 DOI: 10.1038/emboj.2009.119 |
0.629 |
|
2009 |
Huertas P, Jackson SP. Human CtIP mediates cell cycle control of DNA end resection and double strand break repair. The Journal of Biological Chemistry. 284: 9558-65. PMID 19202191 DOI: 10.1074/jbc.M808906200 |
0.401 |
|
2009 |
Sollier J, Driscoll R, Castellucci F, Foiani M, Jackson SP, Branzei D. The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair. Molecular Biology of the Cell. 20: 1671-82. PMID 19158389 DOI: 10.1091/Mbc.E08-08-0875 |
0.522 |
|
2008 |
Gravel S, Chapman JR, Magill C, Jackson SP. DNA helicases Sgs1 and BLM promote DNA double-strand break resection Genes and Development. 22: 2767-2772. PMID 18923075 DOI: 10.1101/gad.503108 |
0.487 |
|
2008 |
Huertas P, Cortés-Ledesma F, Sartori AA, Aguilera A, Jackson SP. CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature. 455: 689-92. PMID 18716619 DOI: 10.1038/nature07215 |
0.474 |
|
2008 |
Chapman JR, Jackson SP. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage Embo Reports. 9: 795-801. PMID 18583988 DOI: 10.1038/embor.2008.103 |
0.538 |
|
2008 |
Jackson S. Targeting the DNA-damage response as a therapeutic strategy European Journal of Cancer Supplements. 6: 119. DOI: 10.1016/S1359-6349(08)71629-X |
0.38 |
|
2007 |
Xie A, Hartlerode A, Stucki M, Odate S, Puget N, Kwok A, Nagaraju G, Yan C, Alt FW, Chen J, Jackson SP, Scully R. Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair. Molecular Cell. 28: 1045-57. PMID 18158901 DOI: 10.1016/J.Molcel.2007.12.005 |
0.353 |
|
2007 |
Kolas NK, Chapman JR, Nakada S, Ylanko J, Chahwan R, Sweeney FD, Panier S, Mendez M, Wildenhain J, Thomson TM, Pelletier L, Jackson SP, Durocher D. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science (New York, N.Y.). 318: 1637-40. PMID 18006705 DOI: 10.1126/Science.1150034 |
0.828 |
|
2007 |
Sartori AA, Lukas C, Coates J, Mistrik M, Fu S, Bartek J, Baer R, Lukas J, Jackson SP. Human CtIP promotes DNA end resection. Nature. 450: 509-14. PMID 17965729 DOI: 10.1038/Nature06337 |
0.47 |
|
2007 |
Hammet A, Magill C, Heierhorst J, Jackson SP. Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast. Embo Reports. 8: 851-7. PMID 17721446 DOI: 10.1038/sj.embor.7401036 |
0.381 |
|
2007 |
Meier A, Fiegler H, Muñoz P, Ellis P, Rigler D, Langford C, Blasco MA, Carter N, Jackson SP. Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres. The Embo Journal. 26: 2707-18. PMID 17491589 DOI: 10.1038/sj.emboj.7601719 |
0.442 |
|
2007 |
Difilippantonio S, Celeste A, Kruhlak MJ, Lee Y, Difilippantonio MJ, Feigenbaum L, Jackson SP, McKinnon PJ, Nussenzweig A. Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis. The Journal of Experimental Medicine. 204: 1003-11. PMID 17485521 DOI: 10.1084/Jem.20070319 |
0.402 |
|
2007 |
Xhemalce B, Miller KM, Driscoll R, Masumoto H, Jackson SP, Kouzarides T, Verreault A, Arcangioli B. Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe. The Journal of Biological Chemistry. 282: 15040-7. PMID 17369611 DOI: 10.1074/Jbc.M701197200 |
0.571 |
|
2007 |
Driscoll R, Hudson A, Jackson SP. Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56. Science (New York, N.Y.). 315: 649-52. PMID 17272722 DOI: 10.1126/SCIENCE.1135862 |
0.37 |
|
2006 |
Ahnesorg P, Jackson SP. The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint. Dna Repair. 6: 190-201. PMID 17101301 DOI: 10.1016/J.DNAREP.2006.09.010 |
0.534 |
|
2006 |
Henderson MJ, Munoz MA, Saunders DN, Clancy JL, Russell AJ, Williams B, Pappin D, Khanna KK, Jackson SP, Sutherland RL, Watts CK. EDD mediates DNA damage-induced activation of CHK2. The Journal of Biological Chemistry. 281: 39990-40000. PMID 17074762 DOI: 10.1074/jbc.M602818200 |
0.51 |
|
2006 |
Hentges P, Ahnesorg P, Pitcher RS, Bruce CK, Kysela B, Green AJ, Bianchi J, Wilson TE, Jackson SP, Doherty AJ. Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos. The Journal of Biological Chemistry. 281: 37517-26. PMID 17038309 DOI: 10.1074/jbc.M608727200 |
0.45 |
|
2006 |
Grenon M, Magill CP, Lowndes NF, Jackson SP. Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation. Fems Yeast Research. 6: 836-47. PMID 16879433 DOI: 10.1111/j.1567-1364.2006.00076.x |
0.367 |
|
2006 |
Stucki M, Jackson SP. gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. Dna Repair. 5: 534-43. PMID 16531125 DOI: 10.1016/J.DNAREP.2006.01.012 |
0.497 |
|
2006 |
Ahnesorg P, Smith P, Jackson SP. XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. Cell. 124: 301-13. PMID 16439205 DOI: 10.1016/j.cell.2005.12.031 |
0.494 |
|
2006 |
Doré AS, Furnham N, Davies OR, Sibanda BL, Chirgadze DY, Jackson SP, Pellegrini L, Blundell TL. Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode. Dna Repair. 5: 362-8. PMID 16388993 DOI: 10.1016/J.Dnarep.2005.11.004 |
0.456 |
|
2006 |
Moumen A, Masterson P, O'Connor MJ, Jackson SP. hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage. Cell. 123: 1065-78. PMID 16360036 DOI: 10.1016/j.cell.2005.09.032 |
0.408 |
|
2006 |
Jazayeri A, Falck J, Lukas C, Bartek J, Smith GC, Lukas J, Jackson SP. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nature Cell Biology. 8: 37-45. PMID 16327781 DOI: 10.1038/Ncb1337 |
0.438 |
|
2006 |
Short S, Bourne S, Martindale C, Johnston P, Jackson S. 48 DNA damage response in radioresistant gliomas Radiotherapy and Oncology. 78: S17-S18. DOI: 10.1016/S0167-8140(06)80542-6 |
0.433 |
|
2006 |
Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP. MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks Cell. 124: 1299. DOI: 10.1016/j.cell.2006.03.013 |
0.465 |
|
2005 |
Tutt ANJ, Lord CJ, McCabe N, Farmer H, Turner N, Martin NM, Jackson SP, Smith GCM, Ashworth A. Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer Cold Spring Harbor Symposia On Quantitative Biology. 70: 139-148. PMID 16869747 DOI: 10.1101/sqb.2005.70.012 |
0.376 |
|
2005 |
Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP. MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks Cell. 123: 1213-1226. PMID 16377563 DOI: 10.1016/J.Cell.2005.09.038 |
0.691 |
|
2005 |
Smits VA, Reaper PM, Jackson SP. Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response. Current Biology : Cb. 16: 150-9. PMID 16360315 DOI: 10.1016/j.cub.2005.11.066 |
0.421 |
|
2005 |
Short SC, Bourne S, Martindale C, Woodcock M, Jackson SP. DNA damage responses at low radiation doses Radiation Research. 164: 292-302. PMID 16137202 DOI: 10.1667/RR3421.1 |
0.314 |
|
2005 |
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 434: 917-21. PMID 15829967 DOI: 10.1038/nature03445 |
0.465 |
|
2005 |
Harvey AC, Jackson SP, Downs JA. Saccharomyces cerevisiae histone H2A Ser122 facilitates DNA repair. Genetics. 170: 543-53. PMID 15781691 DOI: 10.1534/genetics.104.038570 |
0.486 |
|
2005 |
Falck J, Coates J, Jackson SP. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature. 434: 605-11. PMID 15758953 DOI: 10.1038/nature03442 |
0.468 |
|
2005 |
Giavara S, Kosmidou E, Hande MP, Bianchi ME, Morgan A, d'Adda di Fagagna F, Jackson SP. Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability. Current Biology : Cb. 15: 68-72. PMID 15649368 DOI: 10.1016/J.Cub.2004.12.065 |
0.472 |
|
2005 |
Lee AC, Fernandez-Capetillo O, Pisupati V, Jackson SP, Nussenzweig A. Specific association of mouse MDC1/NFBD1 with NBS1 at sites of DNA-damage. Cell Cycle (Georgetown, Tex.). 4: 177-82. PMID 15611643 DOI: 10.4161/Cc.4.1.1354 |
0.502 |
|
2005 |
von Zglinicki T, Saretzki G, Ladhoff J, d'Adda di Fagagna F, Jackson SP. Human cell senescence as a DNA damage response. Mechanisms of Ageing and Development. 126: 111-7. PMID 15610769 DOI: 10.1016/j.mad.2004.09.034 |
0.477 |
|
2005 |
Stucki M, Jackson SP. Tudor domains track down DNA breaks. Nature Cell Biology. 6: 1150-2. PMID 15573092 DOI: 10.1038/ncb1204-1150 |
0.406 |
|
2005 |
Stucki M, Jackson SP. MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes. Dna Repair. 3: 953-7. PMID 15279781 DOI: 10.1016/J.DNAREP.2004.03.007 |
0.538 |
|
2004 |
Downs JA, Allard S, Jobin-Robitaille O, Javaheri A, Auger A, Bouchard N, Kron SJ, Jackson SP, Côté J. Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. Molecular Cell. 16: 979-90. PMID 15610740 DOI: 10.1016/J.Molcel.2004.12.003 |
0.459 |
|
2004 |
Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, Orr AI, Reaper PM, Jackson SP, Curtin NJ, Smith GC. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Research. 64: 9152-9. PMID 15604286 DOI: 10.1158/0008-5472.CAN-04-2727 |
0.343 |
|
2004 |
Riballo E, Kühne M, Rief N, Doherty A, Smith GC, Recio MJ, Reis C, Dahm K, Fricke A, Krempler A, Parker AR, Jackson SP, Gennery A, Jeggo PA, Löbrich M. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Molecular Cell. 16: 715-24. PMID 15574327 DOI: 10.1016/J.Molcel.2004.10.029 |
0.41 |
|
2004 |
Squires S, Coates JA, Goldberg M, Toji LH, Jackson SP, Clarke DJ, Johnson RT. p53 prevents the accumulation of double-strand DNA breaks at stalled-replication forks induced by UV in human cells. Cell Cycle (Georgetown, Tex.). 3: 1543-57. PMID 15539956 |
0.45 |
|
2004 |
Lau A, Kanaar R, Jackson SP, O'Connor MJ. Suppression of retroviral infection by the RAD52 DNA repair protein. The Embo Journal. 23: 3421-9. PMID 15297876 DOI: 10.1038/sj.emboj.7600348 |
0.464 |
|
2004 |
d'Adda di Fagagna F, Teo SH, Jackson SP. Functional links between telomeres and proteins of the DNA-damage response. Genes & Development. 18: 1781-99. PMID 15289453 DOI: 10.1101/GAD.1214504 |
0.495 |
|
2004 |
Lukas C, Melander F, Stucki M, Falck J, Bekker-Jensen S, Goldberg M, Lerenthal Y, Jackson SP, Bartek J, Lukas J. Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention Embo Journal. 23: 2674-2683. PMID 15201865 DOI: 10.1038/Sj.Emboj.7600269 |
0.515 |
|
2004 |
Downs JA, Jackson SP. A means to a DNA end: the many roles of Ku. Nature Reviews. Molecular Cell Biology. 5: 367-78. PMID 15122350 DOI: 10.1038/nrm1367 |
0.453 |
|
2004 |
Reaper PM, di Fagagna Fd, Jackson SP. Activation of the DNA damage response by telomere attrition: a passage to cellular senescence. Cell Cycle (Georgetown, Tex.). 3: 543-6. PMID 15034298 |
0.465 |
|
2004 |
Jazayeri A, McAinsh AD, Jackson SP. Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair Proceedings of the National Academy of Sciences of the United States of America. 101: 1644-1649. PMID 14711989 DOI: 10.1073/Pnas.0304797101 |
0.476 |
|
2004 |
Roy R, Meier B, McAinsh AD, Feldmann HM, Jackson SP. Separation-of-function Mutants of Yeast Ku80 Reveal a Yku80p-Sir4p Interaction Involved in Telomeric Silencing Journal of Biological Chemistry. 279: 86-94. PMID 14551211 DOI: 10.1074/Jbc.M306841200 |
0.395 |
|
2003 |
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP. A DNA damage checkpoint response in telomere-initiated senescence. Nature. 426: 194-8. PMID 14608368 DOI: 10.1038/nature02118 |
0.507 |
|
2003 |
Downs JA, Jackson SP. Cancer: protective packaging for DNA. Nature. 424: 732-4. PMID 12917666 DOI: 10.1038/424732a |
0.36 |
|
2003 |
Downs JA, Kosmidou E, Morgan A, Jackson SP. Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. Molecular Cell. 11: 1685-92. PMID 12820979 DOI: 10.1016/S1097-2765(03)00197-7 |
0.4 |
|
2003 |
Goldberg M, Stucki M, Falck J, D'Amours D, Rahman D, Pappin D, Bartek J, Jackson SP. MDC1 is required for the intra-S-phase DNA damage checkpoint Nature. 421: 952-956. PMID 12607003 DOI: 10.1038/nature01445 |
0.418 |
|
2003 |
Bradbury JM, Jackson SP. The complex matter of DNA double-strand break detection. Biochemical Society Transactions. 31: 40-4. PMID 12546650 DOI: 10.1042/BST0310040 |
0.512 |
|
2003 |
Dionne I, Nookala RK, Jackson SP, Doherty AJ, Bell SD. A heterotrimeric PCNA in the hyperthermophilic archaeon Sulfolobus solfataricus. Molecular Cell. 11: 275-82. PMID 12535540 DOI: 10.1016/S1097-2765(02)00824-9 |
0.457 |
|
2003 |
d'Adda di Fagagna F, Weller GR, Doherty AJ, Jackson SP. The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku. Embo Reports. 4: 47-52. PMID 12524520 DOI: 10.1038/sj.embor.embor709 |
0.479 |
|
2003 |
Bradbury JM, Jackson SP. Double-Strand Break Recognition and Its Repair by Nonhomologous End Joining Handbook of Cell Signaling. 3: 219-224. DOI: 10.1016/B978-012124546-7/50666-5 |
0.335 |
|
2002 |
Weller GR, Kysela B, Roy R, Tonkin LM, Scanlan E, Della M, Devine SK, Day JP, Wilkinson A, d'Adda di Fagagna F, Devine KM, Bowater RP, Jeggo PA, Jackson SP, Doherty AJ. Identification of a DNA nonhomologous end-joining complex in bacteria. Science (New York, N.Y.). 297: 1686-9. PMID 12215643 DOI: 10.1126/Science.1074584 |
0.517 |
|
2002 |
Rouse J, Jackson SP. Interfaces between the detection, signaling, and repair of DNA damage. Science (New York, N.Y.). 297: 547-51. PMID 12142523 DOI: 10.1126/science.1074740 |
0.464 |
|
2002 |
Chang JH, Kim HC, Hwang KY, Lee JW, Jackson SP, Bell SD, Cho Y. Structural basis for the NAD-dependent deacetylase mechanism of Sir2. The Journal of Biological Chemistry. 277: 34489-98. PMID 12091395 DOI: 10.1074/jbc.M205460200 |
0.317 |
|
2002 |
Li J, Williams BL, Haire LF, Goldberg M, Wilker E, Durocher D, Yaffe MB, Jackson SP, Smerdon SJ. Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2. Molecular Cell. 9: 1045-54. PMID 12049740 DOI: 10.1016/S1097-2765(02)00527-0 |
0.717 |
|
2002 |
Jackson SP. Sensing and repairing DNA double-strand breaks. Carcinogenesis. 23: 687-96. PMID 12016139 DOI: 10.1093/CARCIN/23.5.687 |
0.474 |
|
2002 |
D'Amours D, Jackson SP. The Mre11 complex: at the crossroads of dna repair and checkpoint signalling. Nature Reviews. Molecular Cell Biology. 3: 317-27. PMID 11988766 DOI: 10.1038/nrm805 |
0.46 |
|
2002 |
Rouse J, Jackson SP. Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo. Molecular Cell. 9: 857-69. PMID 11983176 DOI: 10.1016/S1097-2765(02)00507-5 |
0.511 |
|
2002 |
Jazayeri A, Jackson SP. Screening the yeast genome for new DNA-repair genes. Genome Biology. 3: REVIEWS1009. PMID 11983062 DOI: 10.1186/gb-2002-3-4-reviews1009 |
0.402 |
|
2002 |
Durocher D, Jackson SP. The FHA domain. Febs Letters. 513: 58-66. PMID 11911881 DOI: 10.1016/S0014-5793(01)03294-X |
0.562 |
|
2002 |
Doherty AJ, Jackson SP. DNA repair: how Ku makes ends meet. Current Biology : Cb. 11: R920-4. PMID 11719239 DOI: 10.1016/S0960-9822(01)00555-3 |
0.481 |
|
2002 |
Jackson SP. Detecting, signalling and repairing DNA double-strand breaks. Biochemical Society Transactions. 29: 655-61. PMID 11709049 DOI: 10.1042/0300-5127:0290655 |
0.504 |
|
2001 |
Sibanda BL, Critchlow SE, Begun J, Pei XY, Jackson SP, Blundell TL, Pellegrini L. Crystal structure of an Xrcc4-DNA ligase IV complex. Nature Structural Biology. 8: 1015-9. PMID 11702069 DOI: 10.1038/nsb725 |
0.427 |
|
2001 |
D'Amours D, Jackson SP. The yeast Xrs2 complex functions in S phase checkpoint regulation. Genes & Development. 15: 2238-49. PMID 11544181 DOI: 10.1101/GAD.208701 |
0.451 |
|
2001 |
d'Adda di Fagagna F, Hande MP, Tong WM, Roth D, Lansdorp PM, Wang ZQ, Jackson SP. Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Current Biology : Cb. 11: 1192-6. PMID 11516951 DOI: 10.1016/S0960-9822(01)00328-1 |
0.456 |
|
2001 |
Freire R, d'Adda Di Fagagna F, Wu L, Pedrazzi G, Stagljar I, Hickson ID, Jackson SP. Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha. Nucleic Acids Research. 29: 3172-80. PMID 11470874 DOI: 10.1093/NAR/29.15.3172 |
0.321 |
|
2001 |
Doherty AJ, Jackson SP, Weller GR. Identification of bacterial homologues of the Ku DNA repair proteins. Febs Letters. 500: 186-8. PMID 11445083 DOI: 10.1016/S0014-5793(01)02589-3 |
0.458 |
|
2001 |
Teo SH, Jackson SP. Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant. Embo Reports. 2: 197-202. PMID 11266360 DOI: 10.1093/embo-reports/kve038 |
0.488 |
|
2001 |
Durocher D, Jackson SP. DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? Current Opinion in Cell Biology. 13: 225-31. PMID 11248557 DOI: 10.1016/S0955-0674(00)00201-5 |
0.717 |
|
2001 |
Khanna KK, Jackson SP. DNA double-strand breaks: signaling, repair and the cancer connection. Nature Genetics. 27: 247-54. PMID 11242102 DOI: 10.1038/85798 |
0.514 |
|
2001 |
Downs JA, Lowndes NF, Jackson SP. A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature. 408: 1001-4. PMID 11140636 DOI: 10.1038/35050000 |
0.504 |
|
2001 |
Jackson S. Signalling and repair of DNA damage Biochemical Society Transactions. 29: A91-A91. DOI: 10.1042/BST029A091A |
0.437 |
|
2001 |
Jackson SP. Detecting, signalling and repairing DNA double-strand breaks Biochemical Society Transactions. 29: 655-661. DOI: 10.1042/bst0290655 |
0.504 |
|
2000 |
Durocher D, Smerdon SJ, Yaffe MB, Jackson SP. The FHA domain in DNA repair and checkpoint signaling Cold Spring Harbor Symposia On Quantitative Biology. 65: 423-431. PMID 12760058 DOI: 10.1101/Sqb.2000.65.423 |
0.733 |
|
2000 |
Durocher D, Taylor IA, Sarbassova D, Haire LF, Westcott SL, Jackson SP, Smerdon SJ, Yaffe MB. The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms. Molecular Cell. 6: 1169-82. PMID 11106755 DOI: 10.1016/S1097-2765(00)00114-3 |
0.688 |
|
2000 |
Rouse J, Jackson SP. LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae. The Embo Journal. 19: 5801-12. PMID 11060031 DOI: 10.1093/emboj/19.21.5801 |
0.521 |
|
2000 |
Teo SH, Jackson SP. Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks. Current Biology : Cb. 10: 165-8. PMID 10679327 DOI: 10.1016/S0960-9822(00)00317-1 |
0.537 |
|
2000 |
Lakin ND, Jackson SP. Regulation of p53 in response to DNA damage. Oncogene. 18: 7644-55. PMID 10618704 DOI: 10.1038/sj.onc.1203015 |
0.428 |
|
1999 |
Featherstone C, Jackson SP. DNA double-strand break repair. Current Biology : Cb. 9: R759-61. PMID 10531043 DOI: 10.1016/S0960-9822(00)80005-6 |
0.471 |
|
1999 |
Durocher D, Henckel J, Fersht AR, Jackson SP. The FHA domain is a modular phosphopeptide recognition motif. Molecular Cell. 4: 387-94. PMID 10518219 DOI: 10.1016/S1097-2765(00)80340-8 |
0.568 |
|
1999 |
McAinsh AD, Scott-Drew S, Murray JAH, Jackson SP. DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p Current Biology. 9: 963-966. PMID 10508591 DOI: 10.1016/S0960-9822(99)80424-2 |
0.533 |
|
1999 |
Smith GC, Cary RB, Lakin ND, Hann BC, Teo SH, Chen DJ, Jackson SP. Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM. Proceedings of the National Academy of Sciences of the United States of America. 96: 11134-9. PMID 10500142 DOI: 10.1073/PNAS.96.20.11134 |
0.483 |
|
1999 |
d'Adda di Fagagna F, Hande MP, Tong WM, Lansdorp PM, Wang ZQ, Jackson SP. Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability. Nature Genetics. 23: 76-80. PMID 10471503 DOI: 10.1038/12680 |
0.4 |
|
1999 |
Gell D, Jackson SP. Mapping of protein-protein interactions within the DNA-dependent protein kinase complex. Nucleic Acids Research. 27: 3494-502. PMID 10446239 DOI: 10.1093/NAR/27.17.3494 |
0.454 |
|
1999 |
Lakin ND, Hann BC, Jackson SP. The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53. Oncogene. 18: 3989-95. PMID 10435622 DOI: 10.1038/sj.onc.1202973 |
0.443 |
|
1999 |
Riballo E, Critchlow SE, Teo SH, Doherty AJ, Priestley A, Broughton B, Kysela B, Beamish H, Plowman N, Arlett CF, Lehmann AR, Jackson SP, Jeggo PA. Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient. Current Biology : Cb. 9: 699-702. PMID 10395545 DOI: 10.1016/S0960-9822(99)80311-X |
0.46 |
|
1999 |
Moens PB, Tarsounas M, Morita T, Habu T, Rottinghaus ST, Freire R, Jackson SP, Barlow C, Wynshaw-Boris A. The association of ATR protein with mouse meiotic chromosome cores. Chromosoma. 108: 95-102. PMID 10382071 DOI: 10.1007/S004120050356 |
0.318 |
|
1999 |
Featherstone C, Jackson SP. Ku, a DNA repair protein with multiple cellular functions? Mutation Research. 434: 3-15. PMID 10377944 DOI: 10.1016/S0921-8777(99)00006-3 |
0.508 |
|
1999 |
Plumb MA, Smith GC, Cunniffe SM, Jackson SP, O'Neill P. DNA-PK activation by ionizing radiation-induced DNA single-strand breaks. International Journal of Radiation Biology. 75: 553-61. PMID 10374937 DOI: 10.1080/095530099140195 |
0.452 |
|
1999 |
Smith GC, Jackson SP. The DNA-dependent protein kinase. Genes & Development. 13: 916-34. PMID 10215620 DOI: 10.1101/GAD.13.8.916 |
0.398 |
|
1999 |
Jackson SP. Colworth Medal lecture. Detection, repair and signalling of DNA double-strand breaks. Biochemical Society Transactions. 27: 1-13. PMID 10093700 DOI: 10.1042/BST0270001 |
0.424 |
|
1998 |
Critchlow SE, Jackson SP. DNA end-joining: from yeast to man. Trends in Biochemical Sciences. 23: 394-8. PMID 9810228 DOI: 10.1016/S0968-0004(98)01284-5 |
0.451 |
|
1998 |
Taccioli GE, Amatucci AG, Beamish HJ, Gell D, Xiang XH, Torres Arzayus MI, Priestley A, Jackson SP, Marshak Rothstein A, Jeggo PA, Herrera VL. Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity. Immunity. 9: 355-66. PMID 9768755 DOI: 10.1016/S1074-7613(00)80618-4 |
0.453 |
|
1998 |
Featherstone C, Jackson SP. DNA repair: the Nijmegen breakage syndrome protein. Current Biology : Cb. 8: R622-5. PMID 9742394 DOI: 10.1016/S0960-9822(98)70392-6 |
0.391 |
|
1998 |
Freire R, Murguía JR, Tarsounas M, Lowndes NF, Moens PB, Jackson SP. Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis. Genes & Development. 12: 2560-73. PMID 9716408 DOI: 10.1101/GAD.12.16.2560 |
0.42 |
|
1998 |
Yavuzer U, Smith GC, Bliss T, Werner D, Jackson SP. DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D. Genes & Development. 12: 2188-99. PMID 9679063 DOI: 10.1101/GAD.12.14.2188 |
0.484 |
|
1998 |
Qureshi SA, Jackson SP. Sequence-specific DNA binding by the S. shibatae TFIIB homolog, TFB, and its effect on promoter strength. Molecular Cell. 1: 389-400. PMID 9660923 DOI: 10.1016/S1097-2765(00)80039-8 |
0.393 |
|
1998 |
Escarceller M, Buchwald M, Singleton BK, Jeggo PA, Jackson SP, Moustacchi E, Papadopoulo D. Fanconi anemia C gene product plays a role in the fidelity of blunt DNA end-joining. Journal of Molecular Biology. 279: 375-85. PMID 9642044 DOI: 10.1006/jmbi.1998.1784 |
0.351 |
|
1998 |
Errami A, He DM, Friedl AA, Overkamp WJ, Morolli B, Hendrickson EA, Eckardt-Schupp F, Oshimura M, Lohman PH, Jackson SP, Zdzienicka MZ. XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation. Nucleic Acids Research. 26: 3146-53. PMID 9628911 DOI: 10.1093/nar/26.13.3146 |
0.441 |
|
1998 |
Priestley A, Beamish HJ, Gell D, Amatucci AG, Muhlmann-Diaz MC, Singleton BK, Smith GC, Blunt T, Schalkwyk LC, Bedford JS, Jackson SP, Jeggo PA, Taccioli GE. Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20. Nucleic Acids Research. 26: 1965-73. PMID 9518490 DOI: 10.1093/Nar/26.8.1965 |
0.456 |
|
1998 |
Boulton SJ, Jackson SP. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. The Embo Journal. 17: 1819-28. PMID 9501103 DOI: 10.1093/emboj/17.6.1819 |
0.692 |
|
1998 |
Jackson SP. DNA-dependent protein kinase. The International Journal of Biochemistry & Cell Biology. 29: 935-8. PMID 9375373 DOI: 10.1016/S1357-2725(97)00006-X |
0.527 |
|
1997 |
Morrison C, Smith GC, Stingl L, Jackson SP, Wagner EF, Wang ZQ. Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis. Nature Genetics. 17: 479-82. PMID 9398855 DOI: 10.1038/Ng1297-479 |
0.437 |
|
1997 |
Jackson SP. Genomic stability. Silencing and DNA repair connect. Nature. 388: 829-30. PMID 9278039 DOI: 10.1038/42136 |
0.417 |
|
1997 |
Critchlow SE, Bowater RP, Jackson SP. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Current Biology : Cb. 7: 588-98. PMID 9259561 DOI: 10.1016/S0960-9822(06)00258-2 |
0.518 |
|
1997 |
Singleton BK, Priestley A, Steingrimsdottir H, Gell D, Blunt T, Jackson SP, Lehmann AR, Jeggo PA. Molecular and biochemical characterization of xrs mutants defective in Ku80. Molecular and Cellular Biology. 17: 1264-73. PMID 9032253 DOI: 10.1128/Mcb.17.3.1264 |
0.375 |
|
1997 |
Boulton SJ, Jackson SP. Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Research. 24: 4639-48. PMID 8972848 DOI: 10.1093/NAR/24.23.4639 |
0.709 |
|
1997 |
Grawunder U, Finnie N, Jackson SP, Riwar B, Jessberger R. Expression of DNA-dependent protein kinase holoenzyme upon induction of lymphocyte differentiation and V(D)J recombination. European Journal of Biochemistry. 241: 931-40. PMID 8944785 DOI: 10.1111/J.1432-1033.1996.00931.X |
0.377 |
|
1997 |
Jackson SP. The recognition of DNA damage. Current Opinion in Genetics & Development. 6: 19-25. PMID 8791484 DOI: 10.1016/S0959-437X(96)90005-2 |
0.513 |
|
1996 |
DeDecker BS, O'Brien R, Fleming PJ, Geiger JH, Jackson SP, Sigler PB. The crystal structure of a hyperthermophilic archaeal TATA-box binding protein. Journal of Molecular Biology. 264: 1072-84. PMID 9000631 DOI: 10.1006/jmbi.1996.0697 |
0.344 |
|
1996 |
Blunt T, Gell D, Fox M, Taccioli GE, Lehmann AR, Jackson SP, Jeggo PA. Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse. Proceedings of the National Academy of Sciences of the United States of America. 93: 10285-90. PMID 8816792 DOI: 10.1073/Pnas.93.19.10285 |
0.519 |
|
1996 |
Finnie NJ, Gottlieb TM, Blunt T, Jeggo PA, Jackson SP. DNA-dependent protein kinase defects are linked to deficiencies in DNA repair and V(D)J recombination. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 173-9. PMID 8650264 DOI: 10.1098/Rstb.1996.0014 |
0.516 |
|
1996 |
Boulton SJ, Jackson SP. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. The Embo Journal. 15: 5093-5103. DOI: 10.1002/j.1460-2075.1996.tb00890.x |
0.687 |
|
1995 |
Blunt T, Taccioli GE, Priestley A, Hafezparast M, McMillan T, Liu J, Cole CC, White J, Alt FW, Jackson SP, Schurr E, Lehmann AR, Jeggo PA. A YAC Contig Encompassing the XRCC5 (Ku80) DNA Repair Gene and Complementation of Defective Cells by YAC Protoplast Fusion Genomics. 30: 320-328. PMID 8586433 DOI: 10.1006/Geno.1995.9871 |
0.336 |
|
1995 |
Jackson SP, Jeggo PA. DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK Trends in Biochemical Sciences. 20: 412-415. PMID 8533154 DOI: 10.1016/S0968-0004(00)89090-8 |
0.488 |
|
1995 |
Jeggo PA, Taccioli GE, Jackson SP. Menage a trois: Double strand break repair, V(D)J recombination and DNA-PK Bioessays. 17: 949-957. PMID 8526889 DOI: 10.1002/Bies.950171108 |
0.417 |
|
1995 |
Blunt T, Finnie NJ, Taccioli GE, Smith GCM, Demengeot J, Gottlieb TM, Mizuta R, Varghese AJ, Alt FW, Jeggo PA, Jackson SP. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation Cell. 80: 813-823. PMID 7889575 DOI: 10.1016/0092-8674(95)90360-7 |
0.508 |
|
1995 |
Gottlieb TM, Jackson SP. Protein kinases and DNA damage. Trends in Biochemical Sciences. 19: 500-3. PMID 7855895 DOI: 10.1016/0968-0004(94)90138-4 |
0.502 |
|
1995 |
Kuhn A, Gottlieb TM, Jackson SP, Grummt I. DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I. Genes & Development. 9: 193-203. PMID 7851793 DOI: 10.1101/GAD.9.2.193 |
0.481 |
|
1995 |
Finnie NJ, Gottlieb TM, Blunt T, Jeggo PA, Jackson SP. DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair Proceedings of the National Academy of Sciences of the United States of America. 92: 320-324. PMID 7816841 DOI: 10.1073/Pnas.92.1.320 |
0.524 |
|
1995 |
Hartley KO, Gell D, Smith GC, Zhang H, Divecha N, Connelly MA, Admon A, Lees-Miller SP, Anderson CW, Jackson SP. DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell. 82: 849-56. PMID 7671312 DOI: 10.1016/0092-8674(95)90482-4 |
0.502 |
|
1995 |
Sipley JD, Menninger JC, Hartley KO, Ward DC, Jackson SP, Anderson CW. Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8. Proceedings of the National Academy of Sciences of the United States of America. 92: 7515-9. PMID 7638222 DOI: 10.1073/pnas.92.16.7515 |
0.462 |
|
1995 |
Miller RD, Hogg J, Ozaki JH, Gell D, Jackson SP, Riblet R. Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus. Proceedings of the National Academy of Sciences of the United States of America. 92: 10792-5. PMID 7479885 DOI: 10.1073/PNAS.92.23.10792 |
0.417 |
|
1994 |
Finnie N, Gottlieb T, Hartley K, Jackson SP. Transcription factor phosphorylation by the DNA-dependent protein kinase. Biochemical Society Transactions. 21: 930-5. PMID 8132096 DOI: 10.1042/BST0210930 |
0.358 |
|
1994 |
Taccioli GE, Gottlieb TM, Blunt T, Priestley A, Demengeot J, Mizuta R, Lehmann AR, Alt FW, Jackson SP, Jeggo PA. Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination Science. 265: 1442-1445. PMID 8073286 DOI: 10.1126/Science.8073286 |
0.508 |
|
1993 |
Bannister AJ, Gottlieb TM, Kouzarides T, Jackson SP. c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif. Nucleic Acids Research. 21: 1289-95. PMID 8464713 DOI: 10.1093/Nar/21.5.1289 |
0.429 |
|
1993 |
Gottlieb TM, Jackson SP. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell. 72: 131-42. PMID 8422676 DOI: 10.1016/0092-8674(93)90057-W |
0.508 |
|
1993 |
White RJ, Jackson SP. Mechanism of TATA-binding protein recruitment to a TATA-less class III promoter. Cell. 71: 1041-53. PMID 1458535 DOI: 10.1016/0092-8674(92)90398-V |
0.315 |
|
1991 |
Mastrangelo IA, Courey AJ, Wall JS, Jackson SP, Hough PVC. DNA looping and Sp1 multimer links: A mechanism for transcriptional synergism and enhancement Proceedings of the National Academy of Sciences of the United States of America. 88: 5670-5674. PMID 2062845 DOI: 10.1073/pnas.88.13.5670 |
0.672 |
|
1991 |
Su W, Jackson S, Tjian R, Echols H. DNA looping between sites for transcriptional activation: Self-association of DNA-bound Sp1 Genes and Development. 5: 820-826. PMID 1851121 |
0.652 |
|
1991 |
Li R, Knight JD, Jackson SP, Tjian R, Botchan MR. Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell. 65: 493-505. PMID 1850324 DOI: 10.1016/0092-8674(91)90467-D |
0.549 |
|
1990 |
Jackson SP, MacDonald JJ, Lees-Miller S, Tjian R. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase Cell. 63: 155-165. PMID 2170018 DOI: 10.1016/0092-8674(90)90296-Q |
0.579 |
|
1989 |
Jackson SP, Tjian R. Purification and analysis of RNA polymerase II transcription factors by using wheat germ agglutinin affinity chromatography Proceedings of the National Academy of Sciences of the United States of America. 86: 1781-1785. PMID 2648381 DOI: 10.1073/Pnas.86.6.1781 |
0.472 |
|
1989 |
Courey AJ, Holtzman DA, Jackson SP, Tjian R. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell. 59: 827-36. PMID 2512012 DOI: 10.1016/0092-8674(89)90606-5 |
0.704 |
|
1988 |
Jackson SP, Tjian R. O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell. 55: 125-33. PMID 3139301 DOI: 10.1016/0092-8674(88)90015-3 |
0.47 |
|
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