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Thomas Grutter, PhD - Publications

Affiliations: 
Université de Strasbourg 
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cevoli F, Arnould B, Peralta FA, Grutter T. Untangling Macropore Formation and Current Facilitation in P2X7. International Journal of Molecular Sciences. 24. PMID 37446075 DOI: 10.3390/ijms241310896  0.354
2023 Peralta FA, Balcon M, Martz A, Biljali D, Cevoli F, Arnould B, Taly A, Chataigneau T, Grutter T. Optical control of PIEZO1 channels. Nature Communications. 14: 1269. PMID 36882406 DOI: 10.1038/s41467-023-36931-0  0.448
2022 Dunning K, Peverini L, Grutter T. Using Symmetrical Organic Cation Solutions to Study P2X7 Ion Permeation. Methods in Molecular Biology (Clifton, N.J.). 2510: 239-252. PMID 35776328 DOI: 10.1007/978-1-0716-2384-8_12  0.309
2021 Peverini L, Dunning K, Peralta FA, Grutter T. Photo-isomerizable tweezers to probe ionotropic receptor mechanisms. Current Opinion in Pharmacology. 62: 109-116. PMID 34965483 DOI: 10.1016/j.coph.2021.11.011  0.507
2021 Dunning K, Martz A, Peralta FA, Cevoli F, Boué-Grabot E, Compan V, Gautherat F, Wolf P, Chataigneau T, Grutter T. P2X7 Receptors and TMEM16 Channels Are Functionally Coupled with Implications for Macropore Formation and Current Facilitation. International Journal of Molecular Sciences. 22. PMID 34207150 DOI: 10.3390/ijms22126542  0.386
2021 Dunning K, Grutter T. Manipulation of ion channel gating with photoswitchable tweezers. Methods in Enzymology. 653: 349-376. PMID 34099179 DOI: 10.1016/bs.mie.2020.12.021  0.421
2020 Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F. Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. British Journal of Pharmacology. PMID 33125712 DOI: 10.1111/bph.15299  0.477
2019 Gasparri F, Wengel J, Grutter T, Pless SA. Molecular determinants for agonist recognition and discrimination in P2X2 receptors. The Journal of General Physiology. PMID 31126967 DOI: 10.1085/Jgp.201912347  0.513
2018 Peverini L, Beudez J, Dunning K, Chataigneau T, Grutter T. New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors. Frontiers in Molecular Neuroscience. 11: 265. PMID 30108481 DOI: 10.3389/Fnmol.2018.00265  0.394
2017 Zhu Y, Beudez J, Yu N, Grutter T, Zhao HB. P2X2 Dominant Deafness Mutations Have No Negative Effect on Wild-Type Isoform: Implications for Functional Rescue and in Deafness Mechanism. Frontiers in Molecular Neuroscience. 10: 371. PMID 29180951 DOI: 10.3389/Fnmol.2017.00371  0.37
2017 Harkat M, Peverini L, Cerdan AH, Dunning K, Beudez J, Martz A, Calimet N, Specht A, Cecchini M, Chataigneau T, Grutter T. On the permeation of large organic cations through the pore of ATP-gated P2X receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28442564 DOI: 10.1073/Pnas.1701379114  0.717
2017 Gasparri F, Wengel J, Grutter T, Pless S. Effects of Ligand Conformations and Hetero-Liganded States on P2X2 Receptors Biophysical Journal. 112: 421a. DOI: 10.1016/J.Bpj.2016.11.2250  0.404
2016 Habermacher C, Martz A, Calimet N, Lemoine D, Peverini L, Specht A, Cecchini M, Grutter T. Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel. Elife. 5. PMID 26808983 DOI: 10.7554/Elife.11050  0.817
2015 Habermacher C, Dunning K, Chataigneau T, Grutter T. Molecular structure and function of P2X receptors. Neuropharmacology. PMID 26231831 DOI: 10.1016/J.Neuropharm.2015.07.032  0.853
2015 Kellenberger S, Grutter T. Architectural and functional similarities between trimeric ATP-Gated P2X receptors and acid-sensing ion channels Journal of Molecular Biology. 427: 54-66. PMID 24937752 DOI: 10.1016/J.Jmb.2014.06.004  0.58
2015 Habermacher C, Martz A, Calimet N, Lemoine D, Peverini L, Specht A, Cecchini M, Grutter T. Author response: Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel Elife. DOI: 10.7554/Elife.11050.029  0.805
2013 Chataigneau T, Lemoine D, Grutter T. Exploring the ATP-binding site of P2X receptors. Frontiers in Cellular Neuroscience. 7: 273. PMID 24415999 DOI: 10.3389/Fncel.2013.00273  0.837
2013 Lemoine D, Habermacher C, Martz A, Méry PF, Bouquier N, Diverchy F, Taly A, Rassendren F, Specht A, Grutter T. Optical control of an ion channel gate. Proceedings of the National Academy of Sciences of the United States of America. 110: 20813-8. PMID 24297890 DOI: 10.1073/Pnas.1318715110  0.804
2013 Jiang R, Taly A, Grutter T. Moving through the gate in ATP-activated P2X receptors Trends in Biochemical Sciences. 38: 20-29. PMID 23206935 DOI: 10.1016/J.Tibs.2012.10.006  0.836
2013 Chataigneau T, Lemoine D, Grutter T. Exploring the ATP-binding site of P2X receptors Frontiers in Cellular Neuroscience. 7. DOI: 10.3389/fncel.2013.00273  0.772
2012 Jiang R, Taly A, Lemoine D, Martz A, Specht A, Grutter T. Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor. Channels (Austin, Tex.). 6: 398-402. PMID 22992569 DOI: 10.4161/Chan.21520  0.842
2012 Lemoine D, Jiang R, Taly A, Chataigneau T, Specht A, Grutter T. Ligand-gated ion channels: new insights into neurological disorders and ligand recognition. Chemical Reviews. 112: 6285-318. PMID 22988962 DOI: 10.1021/Cr3000829  0.786
2012 Lörinczi É, Bhargava Y, Marino SF, Taly A, Kaczmarek-Hájek K, Barrantes-Freer A, Dutertre S, Grutter T, Rettinger J, Nicke A. Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 11396-401. PMID 22745172 DOI: 10.1073/Pnas.1118759109  0.531
2012 Jiang R, Taly A, Lemoine D, Martz A, Cunrath O, Grutter T. Tightening of the ATP-binding sites induces the opening of P2X receptor channels Embo Journal. 31: 2134-2143. PMID 22473210 DOI: 10.1038/Emboj.2012.75  0.855
2011 Nasiripourdori A, Taly V, Grutter T, Taly A. From toxins targeting ligand gated ion channels to therapeutic molecules Toxins. 3: 260-293. PMID 22069709 DOI: 10.3390/Toxins3030260  0.496
2011 Jiang R, Lemoine D, Martz A, Taly A, Gonin S, Prado de Carvalho L, Specht A, Grutter T. Agonist trapped in ATP-binding sites of the P2X2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 108: 9066-71. PMID 21576497 DOI: 10.1073/Pnas.1102170108  0.837
2011 Jiang R, Miyamoto A, Martz A, Specht A, Ishibashi H, Kueny-Stotz M, Chassaing S, Brouillard R, de Carvalho LP, Goeldner M, Nabekura J, Nielsen M, Grutter T. Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro. British Journal of Pharmacology. 162: 1326-39. PMID 21133889 DOI: 10.1111/J.1476-5381.2010.01142.X  0.751
2010 Jiang R, Martz A, Gonin S, Taly A, De Carvalho LP, Grutter T. A putative extracellular salt bridge at the subunit interface contributes to the ion channel function of the ATP-gated P2X2 receptor Journal of Biological Chemistry. 285: 15805-15815. PMID 20308075 DOI: 10.1074/Jbc.M110.101980  0.821
2008 Guerlet G, Taly A, Prado de Carvalho L, Martz A, Jiang R, Specht A, Le Novère N, Grutter T. Comparative models of P2X2 receptor support inter-subunit ATP-binding sites. Biochemical and Biophysical Research Communications. 375: 405-9. PMID 18718445 DOI: 10.1016/J.Bbrc.2008.08.030  0.839
2007 Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, Grutter T, Changeux JP, Corringer PJ. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature. 445: 116-9. PMID 17167423 DOI: 10.1038/Nature05371  0.665
2006 Grutter T, de Carvalho LP, Dufresne V, Taly A, Changeux JP. Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel. Journal of Molecular Neuroscience : Mn. 30: 63-4. PMID 17192629 DOI: 10.1385/Jmn:30:1:63  0.699
2006 Taly A, Corringer PJ, Grutter T, Prado de Carvalho L, Karplus M, Changeux JP. Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 16965-70. PMID 17077146 DOI: 10.1073/Pnas.0607477103  0.652
2006 Mourot A, Grutter T, Goeldner M, Kotzyba-Hibert F. Dynamic structural investigations on the torpedo nicotinic acetylcholine receptor by time-resolved photoaffinity labeling. Chembiochem : a European Journal of Chemical Biology. 7: 570-83. PMID 16538695 DOI: 10.1002/Cbic.200500526  0.836
2005 Grutter T, de Carvalho LP, Dufresne V, Taly A, Edelstein SJ, Changeux JP. Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 102: 18207-12. PMID 16319224 DOI: 10.1073/Pnas.0509024102  0.708
2005 Grutter T, Prado de Carvalho L, Virginie D, Taly A, Fischer M, Changeux JP. A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels. Comptes Rendus Biologies. 328: 223-34. PMID 15810546 DOI: 10.1016/J.Crvi.2004.11.004  0.654
2005 Taly A, Delarue M, Grutter T, Nilges M, Le Novère N, Corringer PJ, Changeux JP. Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophysical Journal. 88: 3954-65. PMID 15805177 DOI: 10.1529/Biophysj.104.050229  0.61
2004 Grutter T, Le Novère N, Changeux JP. Rational understanding of nicotinic receptors drug binding. Current Topics in Medicinal Chemistry. 4: 645-50. PMID 14965300 DOI: 10.2174/1568026043451177  0.661
2003 Grutter T, Prado de Carvalho L, Le Novère N, Corringer PJ, Edelstein S, Changeux JP. An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. The Embo Journal. 22: 1990-2003. PMID 12727867 DOI: 10.1093/Emboj/Cdg197  0.59
2003 Che C, Petit G, Kotzyba-Hibert F, Bertrand S, Bertrand D, Grutter T, Goeldner M. Syntheses and biological properties of cysteine-reactive epibatidine derivatives. Bioorganic & Medicinal Chemistry Letters. 13: 1001-4. PMID 12643898 DOI: 10.1016/S0960-894X(03)00092-1  0.778
2002 Grutter T, Bertrand S, Kotzyba-Hibert F, Bertrand D, Goeldner M. Structural reorganization of the acetylcholine binding site of the torpedo nicotinic receptor as revealed by dynamic photoaffinity labeling. Chembiochem : a European Journal of Chemical Biology. 3: 652-8. PMID 12324999 DOI: 10.1002/1439-7633(20020703)3:7<652::Aid-Cbic652>3.0.Co;2-L  0.801
2002 Le Novère N, Grutter T, Changeux JP. Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites. Proceedings of the National Academy of Sciences of the United States of America. 99: 3210-5. PMID 11867716 DOI: 10.1073/Pnas.042699699  0.596
2001 Grutter T, Changeux JP. Nicotinic receptors in wonderland. Trends in Biochemical Sciences. 26: 459-63. PMID 11504610 DOI: 10.1016/S0968-0004(01)01921-1  0.626
2001 Foucaud B, Perret P, Grutter T, Goeldner M. Cysteine mutants as chemical sensors for ligand-receptor interactions. Trends in Pharmacological Sciences. 22: 170-3. PMID 11282416 DOI: 10.1016/S0165-6147(00)01674-6  0.677
2000 Grutter T, Ehret-Sabatier L, Kotzyba-Hibert F, Goeldner M. Photoaffinity labeling of Torpedo nicotinic receptor with the agonist [3H]DCTA: identification of amino acid residues which contribute to the binding of the ester moiety of acetylcholine. Biochemistry. 39: 3034-43. PMID 10715124 DOI: 10.1021/Bi992393O  0.77
1999 Kotzyba-Hibert F, Grutter T, Goeldner M. Molecular investigations on the nicotinic acetylcholine receptor: conformational mapping and dynamic exploration using photoaffinity labeling. Molecular Neurobiology. 20: 45-59. PMID 10595872 DOI: 10.1007/Bf02741364  0.85
1999 Grutter T, Goeldner M, Kotzyba-Hibert F. Nicotinic acetylcholine receptor probed with a photoactivatable agonist: improved labeling specificity by addition of CeIV/glutathione. Extension to laser flash photolabeling. Biochemistry. 38: 7476-84. PMID 10360945 DOI: 10.1021/Bi982748O  0.797
1999 Colas C, Grutter T, Goeldner M. 4-Diazocyclohexa-2,5-dienone derivatives as photoaffinity labels for proteins: Scope and limitations Synlett. 889-892. DOI: 10.1055/S-1999-3102  0.526
1998 Grutter T, Goeldner M, Kotzyba-Hibert F. Photoaffinity labeling of nicotinic acetylcholine receptor with a tritiated agonist: A new tool for investigating the functional, activated state Journal of Physiology-Paris. 92: 436-437. DOI: 10.1016/S0928-4257(99)80050-3  0.785
1997 Kotzyba-Hibert F, Kessler P, Zerbib V, Grutter T, Bogen C, Takeda K, Hammadi A, Knerr L, Goeldner M. Nicotinic acetylcholine receptor labeled with a tritiated, photoactivatable agonist: a new tool for investigating the functional, activated state. Bioconjugate Chemistry. 8: 472-80. PMID 9258443 DOI: 10.1021/Bc970084+  0.834
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