Robert A Craigie - Publications

Affiliations: 
Molecular Virology section NIH (NIDDK) 

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li M, Li Z, Chen X, Cui Y, Engelman AN, Craigie R. HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration. Viruses. 16. PMID 39066328 DOI: 10.3390/v16071166  0.578
2024 Li M, Yang R, Chen X, Wang H, Ghirlando R, Dimitriadis EK, Craigie R. HIV-1 integrase assembles multiple species of stable synaptic complex intasomes that are active for concerted DNA integration in vitro. Journal of Molecular Biology. 168557. PMID 38582148 DOI: 10.1016/j.jmb.2024.168557  0.532
2024 Mahajan PS, Smith SJ, Li M, Craigie R, Hughes SH, Zhao XZ, Burke TR. -Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants. Acs Infectious Diseases. PMID 38346249 DOI: 10.1021/acsinfecdis.3c00525  0.37
2024 Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Aiyer S, Li Z, Craigie R, et al. Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding. Biorxiv : the Preprint Server For Biology. PMID 38328132 DOI: 10.1101/2024.01.26.577436  0.558
2023 Li M, Oliveira Passos D, Shan Z, Smith SJ, Sun Q, Biswas A, Choudhuri I, Strutzenberg TS, Haldane A, Deng N, Li Z, Zhao XZ, Briganti L, Kvaratskhelia M, Burke TR, ... ... Craigie R, et al. Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Science Advances. 9: eadg5953. PMID 37478179 DOI: 10.1126/sciadv.adg5953  0.351
2022 Sapp N, Burge N, Cox K, Prakash P, Balasubramaniam M, Thapa S, Christensen D, Li M, Linderberger J, Kvaratskhelia M, Pandhare J, Craigie R, Poirier MG, Dash C. HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA. Journal of Virology. e0101122. PMID 36094316 DOI: 10.1128/jvi.01011-22  0.658
2021 Passos DO, Li M, Craigie R, Lyumkis D. Retroviral integrase: Structure, mechanism, and inhibition. The Enzymes. 50: 249-300. PMID 34861940 DOI: 10.1016/bs.enz.2021.06.007  0.54
2021 Davids BO, Balasubramaniam M, Sapp N, Prakash P, Ingram S, Li M, Craigie R, Hollis T, Pandhare J, Dash C. Human Three Prime Repair Exonuclease 1 Promotes HIV-1 Integration by Preferentially Degrading Unprocessed Viral DNA. Journal of Virology. JVI0055521. PMID 34105995 DOI: 10.1128/JVI.00555-21  0.676
2021 Craigie R. The molecular biology of HIV integrase. Future Virology. 7: 679-686. PMID 23024700 DOI: 10.2217/FVL.12.56  0.63
2020 Li M, Chen X, Wang H, Jurado KA, Engelman AN, Craigie R. A peptide derived from lens epithelium-derived growth factor stimulates HIV-1 DNA integration and facilitates intasome structural studies. Journal of Molecular Biology. PMID 32061936 DOI: 10.1016/J.Jmb.2020.01.040  0.582
2020 Passos DO, Li M, Jóźwik IK, Zhao XZ, Santos-Martins D, Yang R, Smith SJ, Jeon Y, Forli S, Hughes SH, Burke TR, Craigie R, Lyumkis D. Structural basis for strand transfer inhibitor binding to HIV intasomes. Science (New York, N.Y.). PMID 32001521 DOI: 10.1126/science.aay8015  0.557
2019 Rose KM, Alves Ferreira-Bravo I, Li M, Craigie R, Ditzler MA, Holliger P, DeStefano JJ. Selection of 2'-Deoxy-2'-Fluoroarabino Nucleic Acid (FANA) Aptamers that Bind HIV-1 Integrase with Picomolar Affinity. Acs Chemical Biology. PMID 31560515 DOI: 10.1021/Acschembio.9B00237  0.414
2018 Craigie R. Nucleoprotein Intermediates in HIV-1 DNA Integration: Structure and Function of HIV-1 Intasomes. Sub-Cellular Biochemistry. 88: 189-210. PMID 29900498 DOI: 10.1007/978-981-10-8456-0_9  0.685
2017 Passos DO, Li M, Yang R, Rebensburg SV, Ghirlando R, Jeon Y, Shkriabai N, Kvaratskhelia M, Craigie R, Lyumkis D. Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome. Science (New York, N.Y.). 355: 89-92. PMID 28059769 DOI: 10.1126/Science.Aah5163  0.615
2015 Li M, Lin S, Craigie R. Outer domains of integrase within retroviral intasomes are dispensible for catalysis of DNA integration. Protein Science : a Publication of the Protein Society. PMID 26537415 DOI: 10.1002/pro.2837  0.309
2014 Craigie R, Bushman FD. Host Factors in Retroviral Integration and the Selection of Integration Target Sites. Microbiology Spectrum. 2. PMID 26104434 DOI: 10.1128/Microbiolspec.Mdna3-0026-2014  0.474
2014 Li M, Jurado KA, Lin S, Engelman A, Craigie R. Engineered hyperactive integrase for concerted HIV-1 DNA integration. Plos One. 9: e105078. PMID 25119883 DOI: 10.1371/Journal.Pone.0105078  0.662
2012 da Silva FA, Li M, Rato S, Maia S, Malhó R, Warren K, Harrich D, Craigie R, Barbas C, Goncalves J. Recombinant rabbit single-chain antibodies bind to the catalytic and C-terminal domains of HIV-1 integrase protein and strongly inhibit HIV-1 replication. Biotechnology and Applied Biochemistry. 59: 353-66. PMID 23586912 DOI: 10.1002/Bab.1034  0.523
2012 Yin Z, Lapkouski M, Yang W, Craigie R. Assembly of prototype foamy virus strand transfer complexes on product DNA bypassing catalysis of integration. Protein Science : a Publication of the Protein Society. 21: 1849-57. PMID 23011895 DOI: 10.1002/Pro.2166  0.619
2012 Craigie R, Bushman FD. HIV DNA integration. Cold Spring Harbor Perspectives in Medicine. 2: a006890. PMID 22762018 DOI: 10.1101/Cshperspect.A006890  0.498
2012 Li M, Ivanov V, Mizuuchi M, Mizuuchi K, Craigie R. DNA requirements for assembly and stability of HIV-1 intasomes. Protein Science : a Publication of the Protein Society. 21: 249-57. PMID 22124978 DOI: 10.1002/Pro.2010  0.512
2011 Huang Y, Cai M, Clore GM, Craigie R. No interaction of barrier-to-autointegration factor (BAF) with HIV-1 MA, cone-rod homeobox (Crx) or MAN1-C in absence of DNA. Plos One. 6: e25123. PMID 21966431 DOI: 10.1371/journal.pone.0025123  0.529
2011 Kessl JJ, Li M, Ignatov M, Shkriabai N, Eidahl JO, Feng L, Musier-Forsyth K, Craigie R, Kvaratskhelia M. FRET analysis reveals distinct conformations of in tetramers in the presence of viral DNA or LEDGF/p75 Nucleic Acids Research. 39: 9009-9022. PMID 21771857 DOI: 10.1093/Nar/Gkr581  0.491
2010 Yin Z, Craigie R. Modeling the HIV-1 Intasome: A Prototype View of the Target of Integrase Inhibitors. Viruses. 2: 2777-81. PMID 21994639 DOI: 10.3390/V2122777  0.622
2010 Cai M, Huang Y, Craigie R, Clore GM. Structural basis of the association of HIV-1 matrix protein with DNA. Plos One. 5: e15675. PMID 21203471 DOI: 10.1371/journal.pone.0015675  0.531
2010 Kotova S, Li M, Dimitriadis EK, Craigie R. Nucleoprotein intermediates in HIV-1 DNA integration visualized by atomic force microscopy. Journal of Molecular Biology. 399: 491-500. PMID 20416324 DOI: 10.1016/j.jmb.2010.04.026  0.603
2010 Craigie R. Targeting HIV-1 DNA integration by swapping tethers. Proceedings of the National Academy of Sciences of the United States of America. 107: 2735-6. PMID 20145107 DOI: 10.1073/pnas.0915097107  0.633
2009 Skoko D, Li M, Huang Y, Mizuuchi M, Cai M, Bradley CM, Pease PJ, Xiao B, Marko JF, Craigie R, Mizuuchi K. Barrier-to-autointegration factor (BAF) condenses DNA by looping. Proceedings of the National Academy of Sciences of the United States of America. 106: 16610-5. PMID 19805345 DOI: 10.1073/Pnas.0909077106  0.415
2009 Li M, Craigie R. Nucleoprotein complex intermediates in HIV-1 integration. Methods (San Diego, Calif.). 47: 237-42. PMID 19232539 DOI: 10.1016/j.ymeth.2009.02.001  0.624
2007 Suzuki Y, Craigie R. The road to chromatin - nuclear entry of retroviruses. Nature Reviews. Microbiology. 5: 187-96. PMID 17304248 DOI: 10.1038/nrmicro1579  0.581
2006 Li M, Craigie R. Virology: HIV goes nuclear. Nature. 441: 581-2. PMID 16738646 DOI: 10.1038/441581a  0.471
2006 Li M, Mizuuchi M, Burke TR, Craigie R. Retroviral DNA integration: reaction pathway and critical intermediates. The Embo Journal. 25: 1295-304. PMID 16482214 DOI: 10.1038/sj.emboj.7601005  0.535
2005 Bradley CM, Craigie R. Seeing is believing: Structure of the catalytic domain of HIV-1 integrase in complex with human LEDGF/p75 Proceedings of the National Academy of Sciences of the United States of America. 102: 17543-17544. PMID 16314581 DOI: 10.1073/pnas.0509078102  0.384
2005 Bradley CM, Ronning DR, Ghirlando R, Craigie R, Dyda F. Structural basis for DNA bridging by barrier-to-autointegration factor. Nature Structural & Molecular Biology. 12: 935-6. PMID 16155580 DOI: 10.1038/Nsmb989  0.38
2005 Li M, Craigie R. Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration. The Journal of Biological Chemistry. 280: 29334-9. PMID 15958388 DOI: 10.1074/jbc.M505367200  0.508
2005 Williams KL, Zhang Y, Shkriabai N, Karki RG, Nicklaus MC, Kotrikadze N, Hess S, Le Grice SF, Craigie R, Pathak VK, Kvaratskhelia M. Mass spectrometric analysis of the HIV-1 integrase-pyridoxal 5'-phosphate complex reveals a new binding site for a nucleotide inhibitor. The Journal of Biological Chemistry. 280: 7949-55. PMID 15615720 DOI: 10.1074/Jbc.M413579200  0.417
2004 Suzuki Y, Yang H, Craigie R. LAP2alpha and BAF collaborate to organize the Moloney murine leukemia virus preintegration complex. The Embo Journal. 23: 4670-8. PMID 15510219 DOI: 10.1038/sj.emboj.7600452  0.514
2004 Shkriabai N, Patil SS, Hess S, Budihas SR, Craigie R, Burke TR, Le Grice SF, Kvaratskhelia M. Identification of an inhibitor-binding site to HIV-1 integrase with affinity acetylation and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 101: 6894-9. PMID 15118107 DOI: 10.1073/pnas.0400873101  0.375
2002 Suzuki Y, Craigie R. Regulatory mechanisms by which barrier-to-autointegration factor blocks autointegration and stimulates intermolecular integration of Moloney murine leukemia virus preintegration complexes. Journal of Virology. 76: 12376-80. PMID 12414981 DOI: 10.1128/jvi.76.23.12376-12380.2002  0.507
2002 Segura-Totten M, Kowalski AK, Craigie R, Wilson KL. Barrier-to-autointegration factor: major roles in chromatin decondensation and nuclear assembly. The Journal of Cell Biology. 158: 475-85. PMID 12163470 DOI: 10.1083/Jcb.200202019  0.343
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