| Year |
Citation |
Score |
| 2022 |
Mohamed H, Baryar U, Bashiri A, Selvaratnam R, VanSchouwen B, Melacini G. Identification of Core Allosteric Sites through Temperature- and Nucleus-Invariant Chemical Shift Covariance. Biophysical Journal. PMID 35538664 DOI: 10.1016/j.bpj.2022.05.004 |
0.625 |
|
| 2019 |
Boulton S, Selvaratnam R, Ahmed R, Van K, Cheng X, Melacini G. Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators. Journal of Medicinal Chemistry. PMID 31074269 DOI: 10.1021/Acs.Jmedchem.9B00258 |
0.619 |
|
| 2018 |
Boulton S, Selvaratnam R, Blondeau JP, Lezoualc'h F, Melacini G. Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist. Journal of the American Chemical Society. PMID 30016089 DOI: 10.1021/Jacs.8B05044 |
0.689 |
|
| 2018 |
Boulton S, Selvaratnam R, Ahmed R, Melacini G. Implementation of the NMR CHEmical Shift Covariance Analysis (CHESCA): A Chemical Biologist's Approach to Allostery. Methods in Molecular Biology (Clifton, N.J.). 1688: 391-405. PMID 29151219 DOI: 10.1007/978-1-4939-7386-6_18 |
0.631 |
|
| 2015 |
VanSchouwen B, Selvaratnam R, Giri R, Lorenz R, Herberg FW, Kim C, Melacini G. Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG). The Journal of Biological Chemistry. PMID 26370085 DOI: 10.1074/Jbc.M115.685305 |
0.691 |
|
| 2015 |
Boulton S, Akimoto M, Selvaratnam R, Bashiri A, Melacini G. A Tool Set to Map Dynamic Allosteric Networks through the NMR Chemical Shift Covariance Analysis (CHESCA) Biophysical Journal. 108: 60a. DOI: 10.1016/J.Bpj.2014.11.363 |
0.68 |
|
| 2014 |
Boulton S, Akimoto M, Selvaratnam R, Bashiri A, Melacini G. A tool set to map allosteric networks through the NMR chemical shift covariance analysis. Scientific Reports. 4: 7306. PMID 25482377 DOI: 10.1038/Srep07306 |
0.661 |
|
| 2014 |
Akimoto M, Zhang Z, Boulton S, Selvaratnam R, Van Schouwen B, Gloyd M, Accili EA, Lange OF, Melacini G. A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP Journal of Biological Chemistry. 289: 22205-22220. PMID 24878962 DOI: 10.1074/Jbc.M114.572164 |
0.641 |
|
| 2014 |
Boulton S, Akimoto M, VanSchouwen B, Moleschi K, Selvaratnam R, Giri R, Melacini G. Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR. Biochemical Society Transactions. 42: 302-7. PMID 24646235 DOI: 10.1042/Bst20130282 |
0.695 |
|
| 2014 |
Akimoto M, Moleschi K, Boulton S, VanSchouwen B, Selvaratnam R, Taylor SS, Melacini G. Allosteric linkers in cAMP signalling. Biochemical Society Transactions. 42: 139-44. PMID 24450641 DOI: 10.1042/Bst20130257 |
0.665 |
|
| 2014 |
Matthews LA, Selvaratnam R, Jones DR, Akimoto M, McConkey BJ, Melacini G, Duncker BP, Guarné A. A novel non-canonical forkhead-associated (FHA) domain-binding interface mediates the interaction between Rad53 and Dbf4 proteins. The Journal of Biological Chemistry. 289: 2589-99. PMID 24285546 DOI: 10.1074/Jbc.M113.517060 |
0.618 |
|
| 2014 |
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG i Structure. 22: 116-124. PMID 24239458 DOI: 10.1016/J.Str.2013.09.021 |
0.694 |
|
| 2014 |
Boulton S, Akimoto M, Selvaratnam R, Bashiri A, Melacini G. A tool set to map allosteric networks through the NMR chemical shift covariance analysis Scientific Reports. 4. DOI: 10.1038/srep07306 |
0.537 |
|
| 2014 |
Algamal M, Milojevic J, Jafari N, Zhang S, Selvaratnam R, Melacini G. Finding Order in Disorder: Probing Transient Functional States in the Amyloidogenic Alzheimer's Aβ Peptide Using the NMR Chemical Shift Covariance Analysis (CHESCA) Biophysical Journal. 106: 236a. DOI: 10.1016/J.Bpj.2013.11.1386 |
0.71 |
|
| 2013 |
Son I, Selvaratnam R, Dubins DN, Melacini G, Chalikian TV. Ultrasonic and densimetric characterization of the association of cyclic AMP with the cAMP-binding domain of the exchange protein EPAC1 Journal of Physical Chemistry B. 117: 10779-10784. PMID 23968295 DOI: 10.1021/Jp406451P |
0.643 |
|
| 2013 |
Akimoto M, Selvaratnam R, McNicholl ET, Verma G, Taylor SS, Melacini G. Signaling through dynamic linkers as revealed by PKA. Proceedings of the National Academy of Sciences of the United States of America. 110: 14231-6. PMID 23946424 DOI: 10.1073/Pnas.1312644110 |
0.634 |
|
| 2013 |
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon E, Zhao C, Casteel DE, Bertinetti D, VanSchouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Structures of human PKG reveal cGMP-selectived activation mechanisms Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-O16 |
0.646 |
|
| 2012 |
Selvaratnam R, Mazhab-Jafari MT, Das R, Melacini G. The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR Plos One. 7. PMID 23185272 DOI: 10.1371/Journal.Pone.0048707 |
0.743 |
|
| 2012 |
Selvaratnam R, Vanschouwen B, Fogolari F, Mazhab-Jafari MT, Das R, Melacini G. The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants Biophysical Journal. 102: 630-639. PMID 22325287 DOI: 10.1016/J.Bpj.2011.12.030 |
0.728 |
|
| 2012 |
Selvaratnam R, Akimoto M, VanSchouwen B, Melacini G. cAMP-dependent allostery and dynamics in Epac: An NMR view Biochemical Society Transactions. 40: 219-223. PMID 22260694 DOI: 10.1042/Bst20110628 |
0.707 |
|
| 2011 |
VanSchouwen B, Selvaratnam R, Fogolari F, Melacini G. Role of dynamics in the autoinhibition and activation of the exchange protein directly activated by cyclic AMP (EPAC) Journal of Biological Chemistry. 286: 42655-42669. PMID 21873431 DOI: 10.1074/Jbc.M111.277723 |
0.686 |
|
| 2011 |
Selvaratnam R, Chowdhury S, VanSchouwena B, Melacini G. Mapping allostery through the covariance analysis of NMR chemical shifts Proceedings of the National Academy of Sciences of the United States of America. 108: 6133-6138. PMID 21444788 DOI: 10.1073/Pnas.1017311108 |
0.709 |
|
| 2009 |
Das R, Chowdhury S, Mazhab-Jafari MT, SilDas S, Selvaratnam R, Melacini G. Dynamically driven ligand selectivity in cyclic nucleotide binding domains Journal of Biological Chemistry. 284: 23682-23696. PMID 19403523 DOI: 10.1074/Jbc.M109.011700 |
0.747 |
|
| 2008 |
Das R, Mazhab-Jafari MT, Chowdhury S, SilDas S, Selvaratnam R, Melacini G. Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP Journal of Biological Chemistry. 283: 19691-19703. PMID 18411261 DOI: 10.1074/Jbc.M802164200 |
0.713 |
|
| Show low-probability matches. |