Steven D. Breazeale, Ph.D.

Affiliations: 
2000 Johns Hopkins University, Baltimore, MD 
Area:
Organic and Bioorganic Chemistry
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"Steven Breazeale"
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Craig A. Townsend grad student 2000 Johns Hopkins
 (Cloning, sequencing, and molecular analysis of NAT and other genes putatively involved in nocardicin A biosynthesis.)
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Publications

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Muñoz-Escudero D, Breazeale SD, Lee M, et al. (2023) Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance. Biochemistry. 62: 2970-2981
Breazeale SD, Ribeiro AA, McClerren AL, et al. (2005) A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose. The Journal of Biological Chemistry. 280: 14154-67
Breazeale SD, Ribeiro AA, Raetz CR. (2003) Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose. The Journal of Biological Chemistry. 278: 24731-9
Breazeale SD, Ribeiro AA, Raetz CR. (2002) Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose. The Journal of Biological Chemistry. 277: 2886-96
Reeve AM, Breazeale SD, Townsend CA. (1998) Purification, characterization, and cloning of an S-adenosylmethionine-dependent 3-amino-3-carboxypropyltransferase in nocardicin biosynthesis. The Journal of Biological Chemistry. 273: 30695-703
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