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Steven H. Kleinstein, Ph.D.

Affiliations: 
Yale University, New Haven, CT 
Area:
Autoimmune Diseases; Computing Methodologies; Carcinoma, Hepatocellular; Immune System Diseases; Influenza Vaccines; Information Science; Leukemia; Lymphoma, Non-Hodgkin; Pattern Recognition, Automated; Virus Diseases; Computational Biology; Autoimmune Di
Website:
https://medicine.yale.edu/lab/kleinstein/people/steven_kleinstein-2.profile
Google:
"Steven Kleinstein"

Parents

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Jaswinder Singh grad student 2002 Princeton
 (Toward quantitative models of germinal center dynamics.)

Children

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Uri Hershberg post-doc (BME Tree)
Kenneth Hoehn post-doc 2018- Yale (Evolution Tree)
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Publications

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Ota M, Hoehn KB, Fernandes-Braga W, et al. (2024) CD23IgG1 memory B cells are poised to switch to pathogenic IgE production in food allergy. Science Translational Medicine. 16: eadi0673
Gabernet G, Marquez S, Bjornson R, et al. (2024) nf-core/airrflow: an adaptive immune receptor repertoire analysis workflow employing the Immcantation framework. Biorxiv : the Preprint Server For Biology
Callahan D, Smita S, Joachim S, et al. (2024) Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states. Nature Immunology
Hoehn KB, Kleinstein SH. (2023) B cell phylogenetics in the single cell era. Trends in Immunology. 45: 62-74
Jensen CG, Sumner JA, Kleinstein SH, et al. (2023) Inferring B cell phylogenies from paired heavy and light chain BCR sequences with Dowser. Biorxiv : the Preprint Server For Biology
Lopes de Assis F, Hoehn KB, Zhang X, et al. (2023) Tracking B cell responses to the SARS-CoV-2 mRNA-1273 vaccine. Cell Reports. 42: 112780
Jiang R, Roy B, Wu Q, et al. (2023) The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties. Immunohorizons. 7: 310-322
Nickerson KM, Smita S, Hoehn KB, et al. (2023) Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of Experimental Medicine. 220
Ota M, Hoehn KB, Ota T, et al. (2023) The memory of pathogenic IgE is contained within CD23 IgG1 memory B cells poised to switch to IgE in food allergy. Biorxiv : the Preprint Server For Biology
Asashima H, Mohanty S, Comi M, et al. (2022) PD-1CXCR5CD4 peripheral helper T cells promote CXCR3 plasmablasts in human acute viral infection. Cell Reports. 111895
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