James C. Costello, Ph.D.
Affiliations: | 2009 | Informatics | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
Bioinformatics Biology, Information ScienceGoogle:
"James Costello"Parents
Sign in to add mentor| Mehmet M. Dalkilic | grad student | 2009 | Indiana University | |
| (Data integration and applications of functional gene networks in Drosophila melanogaster.) | ||||
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Publications
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| Sobral LM, Hicks HM, Parrish JK, et al. (2020) KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma. Molecular Oncology |
| Zhou H, Blevins MA, Hsu JY, et al. (2020) A SIX1/EYA2 small molecule inhibitor disrupts EMT and metastasis. Cancer Research |
| Stern JL, Hibshman G, Hu K, et al. (2020) Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers. Molecular Cancer Research : McR |
| Goodspeed AE, Jean A, Costello JC. (2020) Abstract B08: MSH2 downregulation induces chemoresistance in bladder cancer Clinical Cancer Research. 26 |
| Washino S, Rider LC, Romero L, et al. (2019) Loss of MAP3K7 sensitizes prostate cancer cells to CDK1/2 inhibition and DNA damage by disrupting homologous recombination. Molecular Cancer Research : McR |
| Oliphant MUJ, Vincent MY, Galbraith MD, et al. (2019) Six2 mediates late-stage metastasis via direct regulation of Sox2 and induction of a cancer stem cell program. Cancer Research |
| Jones RT, Zuiverloon TC, Vekony H, et al. (2019) Abstract 2107: Integrative molecular and functional genomic analysis of chemotherapy resistant bladder cancer cell lines identifies novel mediators of therapeutic response Cancer Research |
| Laajala TD, Gerke T, Tyekucheva S, et al. (2019) Modeling genetic heterogeneity of drug response and resistance in cancer Current Opinion in Systems Biology. 17: 8-14 |
| Morgan MJ, Fitzwalter BE, Owens CR, et al. (2018) Metastatic cells are preferentially vulnerable to lysosomal inhibition. Proceedings of the National Academy of Sciences of the United States of America |
| Oliphant MU, Pandey A, Johnson K, et al. (2018) Abstract 5001: Identification of a Six2/Sox2/Nanog stem cell axis that promotes breast cancer metastatic colonization Cancer Research. 78: 5001-5001 |