Cornelis G. Kruse

Affiliations: 
Solvay Pharmaceuticals, Weesp 
Area:
drug discovery
Website:
http://www.knaw.nl/Pages/DEF/27/927.bGFuZz1OTA.html
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"Cornelis Kruse"
Mean distance: 10.56
 

Parents

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Arne van der Gen grad student 1978 Leiden
 (Application of cyclic α-chloro ethers and thioethers in organic synthesis)
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Publications

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Veerman JJN, Klein J, Aben RWM, et al. (2002) Solid-phase synthesis of piperidines by N-acyliminium ion chemistry European Journal of Organic Chemistry. 3133-3139
Van Maarseveen JH, Meester WJN, Veerman JJN, et al. (2001) Development and application of allyl, 2-sulfonylethyl and 2-thioethyl carbamate linkers for solid phase N-acyliminium ion chemistry Journal of the Chemical Society. Perkin Transactions 1. 994-1001
van Maarseveen JH, den Hartog JA, Tipker K, et al. (1998) Design and synthesis of an orally active GPIIb/IIIa antagonist based on a phenylpiperazine scaffold. Bioorganic & Medicinal Chemistry Letters. 8: 1531-6
Chamoin S, Houldsworth S, Kruse CG, et al. (1998) The Suzuki-Miyaura cross coupling reactions on solid support. Link to solution phase directed ortho metalation. The Leznoff acetal linker approach to biaryl and heterobiaryl aldehydes Tetrahedron Letters. 39: 4179-4182
Veerman JJN, Van Maarseveen JH, Visser GM, et al. (1998) Ring-closing metathesis on solid support: Elaboration of a cyclization/cleavage strategy towards unsaturated α-ester-substituted N-heterocycles European Journal of Organic Chemistry. 2583-2589
van Maarseveen JH, Scheeren HW, De Clercq E, et al. (1997) Antiviral and tumor cell antiproliferative SAR studies on tetracyclic eudistomins. II. Bioorganic & Medicinal Chemistry. 5: 955-70
Kuipers W, Kruse CG, van Wijngaarden I, et al. (1997) 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines. Journal of Medicinal Chemistry. 40: 300-12
Warmerdam EGJC, Van Den Nieuwendijk AMCH, Brussee J, et al. (1996) Asymmetric epoxidation of chiral allylic alcohols Tetrahedron Asymmetry. 7: 2539-2550
Warmerdam EGJC, Van Rijn RD, Brussee J, et al. (1996) Synthesis of α-hydroxy-β-amino acids from chiral cyanohydrins Tetrahedron Asymmetry. 7: 1723-1732
Van Maarseveen JH, Den Hartog JAJ, Engelen V, et al. (1996) Solid phase ring-closing metathesis: Cyclization/cleavage approach towards a seven membered cycloolefin Tetrahedron Letters. 37: 8249-8252
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