| Year |
Citation |
Score |
| 2021 |
Yamada Y, Gilliland K, Xiang Z, Haymer D, Crocker KE, Loch MT, Schulte ML, Rodriguez AL, Niswender CM, Jeffrey Conn P, Lindsley CW, Melancon BJ. Positive allosteric modulators (PAMs) of the group II metabotropic glutamate receptors: Design, synthesis, and evaluation as ex-vivo tool compounds. Bioorganic & Medicinal Chemistry Letters. 128342. PMID 34461178 DOI: 10.1016/j.bmcl.2021.128342 |
0.387 |
|
| 2020 |
Cohen AS, Geng L, Zhao P, Fu A, Schulte ML, Graves-Deal R, Washington MK, Berlin J, Coffey RJ, Manning HC. Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer. Translational Oncology. 13: 100828. PMID 32652471 DOI: 10.1016/J.Tranon.2020.100828 |
0.497 |
|
| 2019 |
Yamada Y, Yohn SE, Gilliland K, Loch MT, Schulte ML, Rodriguez AL, Blobaum AL, Niswender CM, Jeffrey Conn P, Lindsley CW. Further exploration of an N-aryl phenoxyethoxy pyridinone-based series of mGlu NAMs: Challenging SAR, enantiospecific activity and in vivo efficacy. Bioorganic & Medicinal Chemistry Letters. PMID 31358468 DOI: 10.1016/J.Bmcl.2019.07.030 |
0.426 |
|
| 2018 |
Rosenberg AJ, Nickels ML, Schulte ML, Manning HC. Automated radiosynthesis of 5-[C]l-glutamine, an important tracer for glutamine utilization. Nuclear Medicine and Biology. 67: 10-14. PMID 30359787 DOI: 10.1016/J.Nucmedbio.2018.09.002 |
0.491 |
|
| 2018 |
Zhang Q, Jeppesen DK, Higginbotham JN, Demory Beckler M, Poulin EJ, Walsh AJ, Skala MC, McKinley ET, Manning HC, Hight MR, Schulte ML, Watt KR, Ayers GD, Wolf MM, Andrejeva G, et al. Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells. Cellular and Molecular Gastroenterology and Hepatology. 5: 627-629.e6. PMID 29930982 DOI: 10.1016/J.Jcmgh.2018.01.013 |
0.448 |
|
| 2018 |
Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, et al. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. Nature Medicine. PMID 29334372 DOI: 10.1038/Nm.4464 |
0.517 |
|
| 2017 |
Li J, Smith JA, Dawson ES, Fu A, Nickels M, Schulte ML, Manning HC. An Optimized Translocator Protein Ligand for Optical Molecular Imaging and Screening. Bioconjugate Chemistry. PMID 28156095 DOI: 10.1021/Acs.Bioconjchem.6B00711 |
0.502 |
|
| 2016 |
Schulte ML, Hight MR, Ayers GD, Liu Q, Shyr Y, Washington MK, Manning HC. Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAF(V600E) In Vivo. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 27770401 DOI: 10.1007/S11307-016-1008-Z |
0.485 |
|
| 2016 |
Li J, Schulte ML, Nickels ML, Manning HC. New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO. Bioorganic & Medicinal Chemistry Letters. PMID 27353534 DOI: 10.1016/J.Bmcl.2016.06.041 |
0.549 |
|
| 2015 |
Schulte ML, Khodadadi AB, Cuthbertson ML, Smith JA, Manning HC. 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport. Bioorganic & Medicinal Chemistry Letters. PMID 26750251 DOI: 10.1016/J.Bmcl.2015.12.031 |
0.543 |
|
| 2015 |
Schulte ML, Dawson ES, Saleh SA, Cuthbertson ML, Manning HC. 2-Substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency. Bioorganic & Medicinal Chemistry Letters. 25: 113-6. PMID 25435145 DOI: 10.1016/J.Bmcl.2014.10.098 |
0.575 |
|
| 2014 |
Wen W, Young SE, Duvernay MT, Schulte ML, Nance KD, Melancon BJ, Engers J, Locuson CW, Wood MR, Daniels JS, Wu W, Lindsley CW, Hamm HE, Stauffer SR. Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354. Bioorganic & Medicinal Chemistry Letters. 24: 4708-13. PMID 25176330 DOI: 10.1016/J.Bmcl.2014.08.021 |
0.647 |
|
| 2014 |
Uddin MI, Buck JR, Schulte ML, Tang D, Saleh SA, Cheung YY, Harp J, Manning HC. Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes. Tetrahedron Letters. 55. PMID 24396154 DOI: 10.1016/J.Tetlet.2013.10.143 |
0.524 |
|
| 2014 |
Schulte ML, Turlington ML, Phatak SS, Harp JM, Stauffer SR, Lindsley CW. ChemInform Abstract: Total Synthesis of Stemaphylline N-Oxide (II) and Related C9a-Epimeric Analogues (III) and (IV). Cheminform. 45: no-no. DOI: 10.1002/chin.201404206 |
0.354 |
|
| 2013 |
Schulte ML, Turlington ML, Phatak SS, Harp JM, Stauffer SR, Lindsley CW. Total synthesis of stemaphylline N-oxide and related C9a-epimeric analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 11847-52. PMID 23956045 DOI: 10.1002/Chem.201302669 |
0.392 |
|
| 2013 |
Young SE, Duvernay MT, Schulte ML, Lindsley CW, Hamm HE. Synthesis of indole derived protease-activated receptor 4 antagonists and characterization in human platelets. Plos One. 8: e65528. PMID 23776495 DOI: 10.1371/Journal.Pone.0065528 |
0.411 |
|
| 2013 |
Senter TJ, Schulte ML, Konkol LC, Wadzinski TE, Lindsley CW. A General, Enantioselective Synthesis of 1-Azabicyclo[m.n.0]alkane Ring Systems. Tetrahedron Letters. 54: 1645-1648. PMID 23459400 DOI: 10.1016/J.Tetlet.2013.01.041 |
0.653 |
|
| 2011 |
Xiang Z, Thompson AD, Brogan JT, Schulte ML, Melancon BJ, Mi D, Lewis LM, Zou B, Yang L, Morrison R, Santomango T, Byers F, Brewer K, Aldrich JS, Yu H, et al. The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson's Disease. Acs Chemical Neuroscience. 2: 730-742. PMID 22368764 DOI: 10.1021/Cn200090Z |
0.335 |
|
| 2011 |
Schulte ML, Lindsley CW. Highly diastereoselective and general synthesis of primary β-fluoroamines. Organic Letters. 13: 5684-7. PMID 21942742 DOI: 10.1021/ol202415j |
0.427 |
|
| 2010 |
Fadeyi OO, Schulte ML, Lindsley CW. General access to chiral N-alkyl terminal aziridines via organocatalysis. Organic Letters. 12: 3276-8. PMID 20552963 DOI: 10.1021/ol101276x |
0.641 |
|
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