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Zhilei Chen, Ph.D. - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Directed evolution, metabolic engineering, natural product, gene therapy, synthetic biology
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Thomas B, Chockalingam K, Chen Z. Methods for Engineering Binders to Multi-Pass Membrane Proteins. Bioengineering (Basel, Switzerland). 10. PMID 38135942 DOI: 10.3390/bioengineering10121351  0.635
2023 Zeng Y, Woolley M, Chockalingam K, Thomas B, Arora S, Hook M, Chen Z. Click display: a rapid and efficient in vitro protein display method for directed evolution. Nucleic Acids Research. PMID 37548398 DOI: 10.1093/nar/gkad643  0.643
2022 Chockalingam K, Kumar A, Song J, Chen Z. Chicken-derived CD20 antibodies with potent B-cell depletion activity. British Journal of Haematology. PMID 36039695 DOI: 10.1111/bjh.18438  0.608
2020 Chockalingam K, Peng Z, Vuong CN, Berghman LR, Chen Z. Golden Gate assembly with a bi-directional promoter (GBid): A simple, scalable method for phage display Fab library creation. Scientific Reports. 10: 2888. PMID 32076016 DOI: 10.1038/S41598-020-59745-2  0.656
2019 Heinzelman P, Low A, Simeon R, Wright GA, Chen Z. De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions. Journal of Biological Engineering. 13: 76. PMID 31636701 DOI: 10.1186/S13036-019-0203-2  0.314
2019 Simeon R, Jiang M, Chamoun-Emanuelli AM, Yu H, Zhang Y, Meng R, Peng Z, Jakana J, Zhang J, Feng H, Chen Z. Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B. Plos Biology. 17: e3000311. PMID 31233493 DOI: 10.1371/Journal.Pbio.3000311  0.348
2018 Kasaraneni N, Chamoun-Emanuelli AM, Wright GA, Chen Z. A simple strategy for retargeting lentiviral vectors to desired cell types via a disulfide-bond-forming protein-peptide pair. Scientific Reports. 8: 10990. PMID 30030466 DOI: 10.1038/S41598-018-29253-5  0.403
2017 Kasaraneni N, Chamoun-Emanuelli AM, Wright G, Chen Z. Retargeting Lentiviruses via SpyCatcher-SpyTag Chemistry for Gene Delivery into Specific Cell Types. Mbio. 8. PMID 29233896 DOI: 10.1128/Mbio.01860-17  0.414
2017 Simeon R, Chen Z. In vitro-engineered non-antibody protein therapeutics. Protein & Cell. PMID 28271446 DOI: 10.1007/S13238-017-0386-6  0.385
2017 Ramirez MA, Chen Z. Split-Intein Triggered Protein Hydrogels. Methods in Molecular Biology (Clifton, N.J.). 1495: 161-171. PMID 27714616 DOI: 10.1007/978-1-4939-6451-2_11  0.333
2017 Guan D, Chen Z. Affinity Purification of Proteins in Tag-Free Form: Split Intein-Mediated Ultrarapid Purification (SIRP). Methods in Molecular Biology (Clifton, N.J.). 1495: 1-12. PMID 27714606 DOI: 10.1007/978-1-4939-6451-2_1  0.336
2015 Chamoun-Emanuelli AM, Wright G, Smith R, Münch RC, Buchholz CJ, Chen Z. In vitro incorporation of a cell-binding protein to a lentiviral vector using an engineered split intein enables targeted delivery of genetic cargo. Biotechnology and Bioengineering. PMID 26108964 DOI: 10.1002/Bit.25685  0.389
2014 Chamoun-Emanuelli AM, Pécheur EI, Chen Z. Benzhydrylpiperazine compounds inhibit cholesterol-dependent cellular entry of hepatitis C virus. Antiviral Research. 109: 141-8. PMID 25019406 DOI: 10.1016/J.Antiviral.2014.06.014  0.338
2014 Guan D, Chen Z. Challenges and recent advances in affinity purification of tag-free proteins. Biotechnology Letters. 36: 1391-406. PMID 24658742 DOI: 10.1007/S10529-014-1509-2  0.364
2014 Ramirez MA, Chen Z. Synthesis of an intein-mediated artificial protein hydrogel. Journal of Visualized Experiments : Jove. e51202. PMID 24514743 DOI: 10.3791/51202  0.334
2013 Simeon RL, Chen Z. A screen for genetic suppressor elements of hepatitis C virus identifies a supercharged protein inhibitor of viral replication. Plos One. 8: e84022. PMID 24391867 DOI: 10.1371/Journal.Pone.0084022  0.376
2013 Simeon RL, Chamoun AM, McMillin T, Chen Z. Discovery and characterization of a new cell-penetrating protein. Acs Chemical Biology. 8: 2678-87. PMID 24047285 DOI: 10.1021/Cb4004089  0.353
2013 Guan D, Ramirez M, Shao L, Jacobsen D, Barrera I, Lutkenhaus J, Chen Z. Two-component protein hydrogels assembled using an engineered disulfide-forming protein-ligand pair. Biomacromolecules. 14: 2909-16. PMID 23848553 DOI: 10.1021/Bm400814U  0.363
2013 Guan D, Ramirez M, Chen Z. Split intein mediated ultra-rapid purification of tagless protein (SIRP). Biotechnology and Bioengineering. 110: 2471-81. PMID 23568256 DOI: 10.1002/Bit.24913  0.34
2013 Chamoun-Emanuelli AM, Pecheur EI, Simeon RL, Huang D, Cremer PS, Chen Z. Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes. Antimicrobial Agents and Chemotherapy. 57: 2571-81. PMID 23529728 DOI: 10.1128/Aac.02593-12  0.355
2013 Ramirez M, Guan D, Ugaz V, Chen Z. Intein-triggered artificial protein hydrogels that support the immobilization of bioactive proteins. Journal of the American Chemical Society. 135: 5290-3. PMID 23509910 DOI: 10.1021/Ja401075S  0.354
2013 Ramirez M, Valdes N, Guan D, Chen Z. Engineering split intein DnaE from Nostoc punctiforme for rapid protein purification. Protein Engineering, Design & Selection : Peds. 26: 215-23. PMID 23223807 DOI: 10.1093/Protein/Gzs097  0.337
2012 Chamoun AM, Chockalingam K, Bobardt M, Simeon R, Chang J, Gallay P, Chen Z. PD 404,182 is a virocidal small molecule that disrupts hepatitis C virus and human immunodeficiency virus. Antimicrobial Agents and Chemotherapy. 56: 672-81. PMID 22083468 DOI: 10.1128/Aac.05722-11  0.616
2010 Chen Z, Simeon RL, Chockalingam K, Rice CM. Creation and characterization of a cell-death reporter cell line for hepatitis C virus infection. Antiviral Research. 86: 220-3. PMID 20188762 DOI: 10.1016/J.Antiviral.2010.02.321  0.633
2010 Chockalingam K, Simeon RL, Rice CM, Chen Z. A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle. Proceedings of the National Academy of Sciences of the United States of America. 107: 3764-9. PMID 20142494 DOI: 10.1073/pnas.0915117107  0.641
2009 Chen Z, Wen F, Sun N, Zhao H. Directed evolution of homing endonuclease I-SceI with altered sequence specificity. Protein Engineering, Design & Selection : Peds. 22: 249-56. PMID 19176595 DOI: 10.1093/Protein/Gzp001  0.6
2005 Chen Z, Zhao H. A highly sensitive selection method for directed evolution of homing endonucleases. Nucleic Acids Research. 33: e154. PMID 16214805 DOI: 10.1093/Nar/Gni148  0.457
2005 Chen Z, Zhao H. Rapid creation of a novel protein function by in vitro coevolution. Journal of Molecular Biology. 348: 1273-82. PMID 15854660 DOI: 10.1016/J.Jmb.2005.02.070  0.507
2005 Chockalingam K, Chen Z, Katzenellenbogen JA, Zhao H. Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches. Proceedings of the National Academy of Sciences of the United States of America. 102: 5691-6. PMID 15811944 DOI: 10.1073/Pnas.0409206102  0.651
2004 Chen Z, Katzenellenbogen BS, Katzenellenbogen JA, Zhao H. Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity. The Journal of Biological Chemistry. 279: 33855-64. PMID 15159406 DOI: 10.1074/Jbc.M402118200  0.439
2003 Chen Z, Zhao H. A highly efficient and sensitive screening method for trans-activation activity of estrogen receptors. Gene. 306: 127-34. PMID 12657474 DOI: 10.1016/S0378-1119(03)00431-1  0.444
2002 Zhao H, Chockalingam K, Chen Z. Directed evolution of enzymes and pathways for industrial biocatalysis. Current Opinion in Biotechnology. 13: 104-10. PMID 11950559 DOI: 10.1016/S0958-1669(02)00291-4  0.639
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