| Year |
Citation |
Score |
| 2019 |
Norleans J, Wang J, Kuryatov A, Leffler A, Doebelin C, Kamenecka TM, Lindstrom J. Discovery of an intrasubunit nicotinic acetylcholine receptor binding site for the positive allosteric modulator Br-PBTC. The Journal of Biological Chemistry. PMID 31221718 DOI: 10.1074/Jbc.Ra118.006253 |
0.398 |
|
| 2017 |
Wang J, Lindstrom J. Orthosteric and Allosteric Potentiation of Heteromeric Neuronal Nicotinic Acetylcholine Receptors. British Journal of Pharmacology. PMID 28199738 DOI: 10.1111/Bph.13745 |
0.358 |
|
| 2016 |
Jain A, Kuryatov A, Wang J, Kamenecka TM, Lindstrom J. Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors. The Journal of Biological Chemistry. PMID 27645992 DOI: 10.1074/Jbc.M116.749150 |
0.339 |
|
| 2015 |
Wang J, Kuryatov A, Jin Z, Norleans J, Kamenecka TM, Kenny PJ, Lindstrom J. A Novel α2/α4 Subtype-Selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting From the C-tail of an α Subunit. The Journal of Biological Chemistry. PMID 26432642 DOI: 10.1074/Jbc.M115.676551 |
0.368 |
|
| 2015 |
Wang J, Kuryatov A, Sriram A, Jin Z, Kamenecka TM, Kenny PJ, Lindstrom J. An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors. The Journal of Biological Chemistry. 290: 13907-18. PMID 25869137 DOI: 10.1074/Jbc.M115.646786 |
0.372 |
|
| 2015 |
Wang J, Kuryatov A, Lindstrom J. Expression of cloned α6* nicotinic acetylcholine receptors. Neuropharmacology. 96: 194-204. PMID 25446669 DOI: 10.1016/J.Neuropharm.2014.10.009 |
0.355 |
|
| 2014 |
Ley CK, Kuryatov A, Wang J, Lindstrom JM. Efficient expression of functional (α6β2)2β3 AChRs in Xenopus oocytes from free subunits using slightly modified α6 subunits. Plos One. 9: e103244. PMID 25068303 DOI: 10.1371/Journal.Pone.0103244 |
0.303 |
|
| 2014 |
Jin Z, Khan P, Shin Y, Wang J, Lin L, Cameron MD, Lindstrom JM, Kenny PJ, Kamenecka TM. Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 24: 674-8. PMID 24365158 DOI: 10.1016/J.Bmcl.2013.11.049 |
0.315 |
|
| 2012 |
Wang J, Papke RL, Stokes C, Horenstein NA. Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 287: 21957-69. PMID 22556416 DOI: 10.1074/Jbc.M112.339796 |
0.608 |
|
| 2011 |
Williams DK, Wang J, Papke RL. Investigation of the molecular mechanism of the α7 nicotinic acetylcholine receptor positive allosteric modulator PNU-120596 provides evidence for two distinct desensitized states. Molecular Pharmacology. 80: 1013-32. PMID 21885620 DOI: 10.1124/Mol.111.074302 |
0.369 |
|
| 2011 |
Williams DK, Wang J, Papke RL. Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations. Biochemical Pharmacology. 82: 915-30. PMID 21575610 DOI: 10.1016/J.Bcp.2011.05.001 |
0.426 |
|
| 2011 |
Papke RL, Stokes C, Williams DK, Wang J, Horenstein NA. Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper. Neuropharmacology. 60: 159-71. PMID 20650284 DOI: 10.1016/J.Neuropharm.2010.07.014 |
0.638 |
|
| 2011 |
Papke RL, Williams DK, Wang J, Horenstein NA. Positive and negative cooperativity of agonist and allosteric modulator binding in alpha7 nAChR: Looking for the therapeutic window Biochemical Pharmacology. 82: 1031. DOI: 10.1016/J.Bcp.2011.07.024 |
0.614 |
|
| 2010 |
Wang J, Horenstein NA, Stokes C, Papke RL. Tethered agonist analogs as site-specific probes for domains of the human α7 nicotinic acetylcholine receptor that differentially regulate activation and desensitization. Molecular Pharmacology. 78: 1012-25. PMID 20823218 DOI: 10.1124/Mol.110.066662 |
0.644 |
|
| 2009 |
Wang J, Papke RL, Horenstein NA. Synthesis of H-bonding probes of alpha7 nAChR agonist selectivity. Bioorganic & Medicinal Chemistry Letters. 19: 474-6. PMID 19081250 DOI: 10.1016/J.Bmcl.2008.11.044 |
0.624 |
|
| Show low-probability matches. |