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Ashutosh S. Jogalekar, Ph.D. - Publications

Affiliations: 
2014- Chemistry Warp Drive Bio 
Area:
Medicinal, Bioorganic, Synthetic Organic, Computational
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Koltun ES, Aay N, Buckl A, Jogalekar AS, Kiss G, Marquez A, Mellem KT, Mordec K, Saldajeno-Concar M, Semko CM, Tibrewal N, Tzitzilonis C, Won W, Smith JA, Wilson SE, et al. Abstract 4878: RMC-4550, an allosteric inhibitor of SHP2: Synthesis, structure, and anti-tumor activity Cancer Research. 78: 4878-4878. DOI: 10.1158/1538-7445.Am2018-4878  0.396
2018 Wildes D, Aay N, Buckl A, Hsieh D, Jogalekar AS, Kiss G, Koltun ES, Marquez A, Mellem KT, Romero J, Saldajeno-Concar M, Schulze CJ, Semko CM, Won W, Nichols RJ, et al. Abstract 4877: Allosteric inhibition of SHP2 variants containing cancer-associated activating mutations Cancer Research. 78: 4877-4877. DOI: 10.1158/1538-7445.Am2018-4877  0.342
2011 Jogalekar AS, Damodaran K, Kriel FH, Jung WH, Alcaraz AA, Zhong S, Curran DP, Snyder JP. Dictyostatin flexibility bridges conformations in solution and in the β-tubulin taxane binding site. Journal of the American Chemical Society. 133: 2427-36. PMID 21299225 DOI: 10.1021/Ja1023817  0.445
2010 Heathcote DA, Patel H, Kroll SH, Hazel P, Periyasamy M, Alikian M, Kanneganti SK, Jogalekar AS, Scheiper B, Barbazanges M, Blum A, Brackow J, Siwicka A, Pace RD, Fuchter MJ, et al. A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration. Journal of Medicinal Chemistry. 53: 8508-22. PMID 21080703 DOI: 10.1021/Jm100732T  0.459
2010 Jogalekar AS. Conformations of stevastelin C3 analogs: Computational deconvolution of NMR data reveals conformational heterogeneity and novel motifs Biopolymers. 93: 968-976. PMID 20564058 DOI: 10.1002/Bip.21504  0.37
2010 Jogalekar AS, Kriel FH, Shi Q, Cornett B, Cicero D, Snyder JP. The discodermolide hairpin structure flows from conformationally stable modular motifs Journal of Medicinal Chemistry. 53: 155-165. PMID 19894728 DOI: 10.1021/Jm9015284  0.386
2009 Ali S, Heathcote DA, Kroll SH, Jogalekar AS, Scheiper B, Patel H, Brackow J, Siwicka A, Fuchter MJ, Periyasamy M, Tolhurst RS, Kanneganti SK, Snyder JP, Liotta DC, Aboagye EO, et al. The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Cancer Research. 69: 6208-15. PMID 19638587 DOI: 10.1158/0008-5472.Can-09-0301  0.456
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