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Mark J. Henderson, Ph.D. - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rai G, Urban DJ, Mott BT, Hu X, Yang SM, Benavides GA, Johnson MS, Squadrito GL, Brimacombe KR, Lee TD, Cheff DM, Zhu H, Henderson MJ, Pohida K, Sulikowski GA, et al. Pyrazole-Based Lactate Dehydrogenase (LDH) Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. Journal of Medicinal Chemistry. PMID 32902275 DOI: 10.1021/Acs.Jmedchem.0C00916  0.346
2020 Thakur A, Tawa GJ, Henderson MJ, Danchik C, Liu S, Shah P, Wang AQ, Dunn G, Kabir M, Padilha EC, Xu X, Simeonov A, Kharbanda S, Stone R, Grewal G. Design, Synthesis and Biological Evaluation of Quinazolin-4-one Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors. Journal of Medicinal Chemistry. PMID 32212730 DOI: 10.1021/Acs.Jmedchem.0C00193  0.335
2019 Clausse V, Tao D, Debnath S, Fang Y, Tagad HD, Wang Y, Sun H, LeClair CA, Mazur SJ, Lane K, Shi ZD, Vasalatiy O, Eells R, Baker LK, Henderson MJ, et al. Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. The Journal of Biological Chemistry. PMID 31481464 DOI: 10.1074/Jbc.Ra119.010201  0.335
2019 Rothan HA, Zhong Y, Sanborn MA, Teoh TC, Ruan J, Yusof R, Hang J, Henderson MJ, Fang S. Small molecule grp94 inhibitors with antiviral activity against Dengue and Zika virus. Antiviral Research. 104590. PMID 31421166 DOI: 10.1016/J.Antiviral.2019.104590  0.333
2019 Ruan J, Rothan HA, Zhong Y, Yan W, Henderson MJ, Chen F, Fang S. A small molecule inhibitor of ER-to-cytosol protein dislocation exhibits anti-dengue and anti-Zika virus activity. Scientific Reports. 9: 10901. PMID 31358863 DOI: 10.1038/S41598-019-47532-7  0.355
2019 Park SJ, Kim Y, Yang SM, Henderson MJ, Yang W, Lindahl M, Urano F, Chen YM. Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 31235574 DOI: 10.1073/Pnas.1813580116  0.324
2019 Zong G, Hu Z, O'Keefe S, Tranter D, Iannotti MJ, Baron L, Hall B, Corfield K, Paatero A, Henderson M, Roboti P, Zhou J, Sun X, Govindarajan M, Rohde J, et al. Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation. Journal of the American Chemical Society. PMID 31059257 DOI: 10.1021/Jacs.8B13506  0.322
2018 Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, et al. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741. PMID 30648156 DOI: 10.1021/Acscentsci.8B00747  0.303
2018 Trychta KA, Bäck S, Henderson MJ, Harvey BK. KDEL Receptors Are Differentially Regulated to Maintain the ER Proteome under Calcium Deficiency. Cell Reports. 25: 1829-1840.e6. PMID 30428351 DOI: 10.1016/J.Celrep.2018.10.055  0.335
2018 Coussens NP, Kales SC, Henderson MJ, Lee OW, Horiuchi KY, Wang Y, Chen Q, Kuznetsova E, Wu J, Chakka S, Cheff DM, Chih-Chien Cheng K, Shinn P, Brimacombe KR, Shen M, et al. High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2. The Journal of Biological Chemistry. PMID 29945974 DOI: 10.1074/Jbc.Ra118.004274  0.355
2018 Martinez NJ, Asawa RR, Cyr MG, Zakharov A, Urban DJ, Roth JS, Wallgren E, Klumpp-Thomas C, Coussens NP, Rai G, Yang SM, Hall MD, Marugan JJ, Simeonov A, Henderson MJ. A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase. Scientific Reports. 8: 9472. PMID 29930256 DOI: 10.1038/S41598-018-27834-Y  0.326
2017 Pei F, Li H, Henderson MJ, Titus SA, Jadhav A, Simeonov A, Cobanoglu MC, Mousavi SH, Shun T, McDermott L, Iyer P, Fioravanti M, Carlisle D, Friedlander RM, Bahar I, et al. Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology. Scientific Reports. 7: 17803. PMID 29259176 DOI: 10.1038/S41598-017-17378-Y  0.318
2017 Urban DJ, Martinez NJ, Davis MI, Brimacombe KR, Cheff DM, Lee TD, Henderson MJ, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, et al. Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays. Scientific Reports. 7: 12758. PMID 28986582 DOI: 10.1038/S41598-017-12630-X  0.337
2017 Wires ES, Henderson MJ, Yan X, Bäck S, Trychta KA, Lutrey MH, Harvey BK. Longitudinal monitoring of Gaussia and Nano luciferase activities to concurrently assess ER calcium homeostasis and ER stress in vivo. Plos One. 12: e0175481. PMID 28403212 DOI: 10.1371/Journal.Pone.0175481  0.344
2016 Wires ES, Howard D, Henderson MJ, Yan X, Trychta KA, Heathward EJ, Zhang Y, Lutrey M, Richie C, Harvey BK. 218. Monitoring ER Stress Activation of the ATF6 Pathway Using Nanoluciferase Molecular Therapy. 24: S85. DOI: 10.1016/S1525-0016(16)33027-1  0.37
2015 Henderson MJ, Baldwin HA, Werley CA, Boccardo S, Whitaker LR, Yan X, Holt GT, Schreiter ER, Looger LL, Cohen AE, Kim DS, Harvey BK. A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store. Plos One. 10: e0139273. PMID 26451944 DOI: 10.1371/Journal.Pone.0139273  0.313
2015 Henderson MJ, Wires ES, Trychta KA, Yan X, Harvey BK. Monitoring Endoplasmic Reticulum Calcium Homeostasis Using a Gaussia Luciferase SERCaMP. Journal of Visualized Experiments : Jove. PMID 26383227 DOI: 10.3791/53199  0.32
2014 Henderson MJ, Wires ES, Trychta KA, Richie CT, Harvey BK. SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis. Molecular Biology of the Cell. 25: 2828-39. PMID 25031430 DOI: 10.1091/Mbc.E14-06-1141  0.312
2013 Henderson MJ, Richie CT, Airavaara M, Wang Y, Harvey BK. Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors. The Journal of Biological Chemistry. 288: 4209-25. PMID 23255601 DOI: 10.1074/Jbc.M112.400648  0.333
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