☰

Sebastian Bernales, Ph.D. - Publications

Affiliations: 
2007 University of California, San Francisco, San Francisco, CA 
Area:
Secretion, UPR
Tree Info Grants Similar researchers PubMed Report error

13/38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Krukowski K, Nolan A, Frias ES, Boone M, Ureta G, Grue K, Paladini MS, Elizarraras E, Delgado L, Bernales S, Walter P, Rosi S. Small molecule cognitive enhancer reverses age-related memory decline in mice. Elife. 9. PMID 33258451 DOI: 10.7554/eLife.62048  0.367
2019 Krukowski K, Nolan A, Frias E, Grue K, Becker M, Ureta G, Delgado L, Bernales S, Sohal VS, Walter P, Rosi S. Integrated stress response inhibitor reverses sex-dependent behavioral and cell-specific deficits after mild repetitive head trauma. Journal of Neurotrauma. PMID 31884883 DOI: 10.1089/Neu.2019.6827  0.418
2015 Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic. Elife. 4. PMID 25986605 DOI: 10.7554/Elife.05434  0.546
2015 Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. Author response: Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic Elife. DOI: 10.7554/Elife.05434.022  0.575
2012 Bernales S, Soto MM, McCullagh E. Unfolded protein stress in the endoplasmic reticulum and mitochondria: a role in neurodegeneration. Frontiers in Aging Neuroscience. 4: 5. PMID 22539924 DOI: 10.3389/Fnagi.2012.00005  0.461
2012 Shuman M, Wells J, Shokat K, Bernales S, Walter P, Shultz L, Goodwin N. A quaternary equation for interdisciplinary medical research (IMR) Journal of Translational Medicine. 10. DOI: 10.1186/1479-5876-10-S2-A49  0.442
2009 So AYL, De La Fuente E, Walter P, Shuman M, Bernales S. The unfolded protein response during prostate cancer development Cancer and Metastasis Reviews. 28: 219-223. PMID 19172382 DOI: 10.1007/S10555-008-9180-5  0.532
2007 Bernales S, Schuck S, Walter P. ER-phagy: selective autophagy of the endoplasmic reticulum. Autophagy. 3: 285-7. PMID 17351330 DOI: 10.4161/Auto.3930  0.525
2006 Bernales S, McDonald KL, Walter P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. Plos Biology. 4: e423. PMID 17132049 DOI: 10.1371/Journal.Pbio.0040423  0.56
2006 Bernales S, Papa FR, Walter P. Intracellular signaling by the unfolded protein response. Annual Review of Cell and Developmental Biology. 22: 487-508. PMID 16822172 DOI: 10.1146/Annurev.Cellbio.21.122303.120200  0.678
2006 Walther TC, Brickner JH, Aguilar PS, Bernales S, Pantoja C, Walter P. Eisosomes mark static sites of endocytosis. Nature. 439: 998-1003. PMID 16496001 DOI: 10.1038/Nature04472  0.648
2004 Leber JH, Bernales S, Walter P. IRE1-independent gain control of the unfolded protein response. Plos Biology. 2: E235. PMID 15314654 DOI: 10.1371/Journal.Pbio.0020235  0.611
2003 Wilhelm V, Villegas J, Miquel A, Engel E, Bernales S, Valenzuela PD, Burzio LO. The complete sequence of the mitochondrial genome of the Chinook salmon, Oncorhynchus tshawytscha. Biological Research. 36: 223-31. PMID 14513717 DOI: 10.4067/S0716-97602003000200012  0.605
Low-probability matches (unlikely to be authored by this person)
2016 Ansari A, Satalkar S, Patil V, Shete AS, Kaur S, Gupta A, Singh S, Raja M, Severance DL, Bernales S, Chakravarty S, Hung DT, Pham SM, Herrera FJ, Rai R. Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR. Bioorganic & Medicinal Chemistry Letters. PMID 27923618 DOI: 10.1016/J.Bmcl.2016.11.080  0.267
2021 Oliveira MM, Lourenco MV, Longo F, Kasica NP, Yang W, Ureta G, Ferreira DDP, Mendonça PHJ, Bernales S, Ma T, De Felice FG, Klann E, Ferreira ST. Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease. Science Signaling. 14. PMID 33531382 DOI: 10.1126/scisignal.abc5429  0.247
2016 Rai R, Banerjee M, Wong DH, McCullagh E, Gupta A, Tripathi S, Riquelme E, Jangir R, Yadav S, Raja M, Melkani P, Dixit V, Patil U, Shrivastava R, Middya S, ... ... Bernales S, et al. Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide. Bioorganic & Medicinal Chemistry Letters. PMID 27614414 DOI: 10.1016/J.Bmcl.2016.08.064  0.225
2013 Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, et al. Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain. Molecular Psychiatry. 18: 882-8. PMID 22869031 DOI: 10.1038/Mp.2012.115  0.197
2013 Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Molecular Psychiatry. 18: 889-97. PMID 22850627 DOI: 10.1038/Mp.2012.106  0.185
2017 Alfaro J, Perez de Arce F, Belmar S, Fuentealba G, Avila P, Ureta G, Flores C, Acuna C, Delgado L, Gaete D, Pujala B, Barde A, Nayak AK, Upendra T, Patel D, ... ... Bernales S, et al. Dual Inhibiton of Bruton's Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat non-Hodgkin's B cell Malignancies. The Journal of Pharmacology and Experimental Therapeutics. PMID 28298527 DOI: 10.1124/jpet.116.238022  0.181
2023 Elson DJ, Nguyen BD, Korjeff NA, Wilferd SF, Puig-Sanvicens V, Sang Jang H, Bernales S, Chakravarty S, Belmar S, Ureta G, Finlay D, Plaisier CL, Kolluri SK. Suppression of Ah Receptor (AhR) increases the aggressiveness of TNBC cells and 11-Cl-BBQ-activated AhR inhibits their growth. Biochemical Pharmacology. 115706. PMID 37506922 DOI: 10.1016/j.bcp.2023.115706  0.173
2023 Elson DJ, Nguyen BD, Bernales S, Chakravarty S, Jang HS, Korjeff NA, Zhang Y, Wilferd SF, Castro DJ, Plaisier CL, Finlay D, Oshima RG, Kolluri SK. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. Acs Pharmacology & Translational Science. 6: 1028-1042. PMID 37470014 DOI: 10.1021/acsptsci.2c00253  0.167
2016 Pujala B, Agarwal AK, Middya S, Banerjee M, Surya A, Nayak AK, Gupta A, Khare S, Guguloth R, Randive NA, Shinde BU, Thakur A, Patel DI, Raja M, Green MJ, ... ... Bernales S, et al. Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK and PI3Kδ. Acs Medicinal Chemistry Letters. 7: 1161-1166. PMID 27994757 DOI: 10.1021/acsmedchemlett.6b00356  0.162
2016 Jadhavar PS, Ramachandran SA, Riquelme E, Gupta A, Quinn KP, Shivakumar D, Ray S, Zende D, Nayak AK, Miglani SK, Sathe BD, Raja M, Farias O, Alfaro I, Belmar S, ... ... Bernales S, et al. Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27717544 DOI: 10.1016/J.Bmcl.2016.09.058  0.157
2017 Ramachandran SA, Jadhavar PS, Miglani SK, Singh MP, Kalane DP, Agarwal AK, Sathe BD, Mukherjee K, Gupta A, Haldar S, Raja M, Singh S, Pham SM, Chakravarty S, Quinn K, ... ... Bernales S, et al. Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28377059 DOI: 10.1016/j.bmcl.2017.03.064  0.149
2012 Bernales S, Guerrero J, Gómez F, Alfaro IE, Protter AA. Effect of MDV3100, a novel androgen receptor signaling inhibitor, on cell proliferation and tumor size in an apocrine breast cancer xenograft model. Journal of Clinical Oncology. 30: 3072-3072. DOI: 10.1200/jco.2012.30.15_suppl.3072  0.142
2011 Delgado L, Alfaro I, Valdovinos D, Gomez F, Protter A, Bernales S. P4-164: Dimebon (Latrepirdine) protects from cell death-induced by mitochondrial stressors and alpha-synuclein over-expression, and decreases alpha-synuclein protein levels in a Parkinson's disease cell model. Alzheimer's & Dementia. 7: S760-S761. DOI: 10.1016/J.Jalz.2011.05.2186  0.14
2012 Prado C, Contreras F, González H, Díaz P, Elgueta D, Barrientos M, Herrada AA, Lladser Á, Bernales S, Pacheco R. Stimulation of dopamine receptor D5 expressed on dendritic cells potentiates Th17-mediated immunity. Journal of Immunology (Baltimore, Md. : 1950). 188: 3062-70. PMID 22379034 DOI: 10.4049/jimmunol.1103096  0.109
2013 Prado C, Bernales S, Pacheco R. Modulation of T-cell mediated immunity by dopamine receptor d5. Endocrine, Metabolic & Immune Disorders Drug Targets. 13: 184-94. PMID 23701196 DOI: 10.2174/1871530311313020007  0.104
2022 Pujala B, Ramachandran SA, Sonawane M, Kamble MM, Panpatil D, Adhikari S, Soni S, Subbareddy V, Shinde BU, Nayak AK, Bansal C, Gupta A, Mukherjee K, Agarwal AK, Guerrero J, ... ... Bernales S, et al. Discovery of MDV6058 (PF-06952229), a selective and potent TGFβR1 inhibitor: Design, synthesis and optimization. Bioorganic & Medicinal Chemistry Letters. 75: 128979. PMID 36089110 DOI: 10.1016/j.bmcl.2022.128979  0.09
2013 Guerrero J, Alfaro IE, Gómez F, Protter AA, Bernales S. Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer. The Prostate. 73: 1291-305. PMID 23765603 DOI: 10.1002/pros.22674  0.088
2014 Cochrane DR, Bernales S, Jacobsen BM, Cittelly DM, Howe EN, D'Amato NC, Spoelstra NS, Edgerton SM, Jean A, Guerrero J, Gómez F, Medicherla S, Alfaro IE, McCullagh E, Jedlicka P, et al. Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide. Breast Cancer Research : Bcr. 16: R7. PMID 24451109 DOI: 10.1186/Bcr3599  0.087
2010 Giorgetti M, Gibbons JA, Bernales S, Alfaro IE, Drieu La Rochelle C, Cremers T, Altar CA, Wronski R, Hutter-Paier B, Protter AA. Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism. The Journal of Pharmacology and Experimental Therapeutics. 333: 748-57. PMID 20194526 DOI: 10.1124/jpet.109.164491  0.081
2023 Arrázola MS, Lira M, Véliz-Valverde F, Quiroz G, Iqbal S, Eaton SL, Lamont DJ, Huerta H, Ureta G, Bernales S, Cárdenas JC, Cerpa W, Wishart TM, Court FA. Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation. Aging Cell. e13814. PMID 36973898 DOI: 10.1111/acel.13814  0.075
2023 Zingg JM, Yang YP, Seely S, Joshi P, Roshid MHO, Iribarren Latasa F, O'Connor G, Alfaro J, Riquelme E, Bernales S, Dikici E, Deo S, Daunert S. Rapid isothermal point-of-care test for screening of SARS-CoV-2 (COVID-19). Aspects of Molecular Medicine. 1: 100002. PMID 37519861 DOI: 10.1016/j.amolm.2023.100002  0.071
2013 González H, Contreras F, Prado C, Elgueta D, Franz D, Bernales S, Pacheco R. Dopamine receptor D3 expressed on CD4+ T cells favors neurodegeneration of dopaminergic neurons during Parkinson's disease. Journal of Immunology (Baltimore, Md. : 1950). 190: 5048-56. PMID 23589621 DOI: 10.4049/jimmunol.1203121  0.067
2009 Pacheco R, Prado CE, Barrientos MJ, Bernales S. Role of dopamine in the physiology of T-cells and dendritic cells. Journal of Neuroimmunology. 216: 8-19. PMID 19732962 DOI: 10.1016/j.jneuroim.2009.07.018  0.049
2010 Bernales S. Apuntes sobre la terapia de pareja y la supervisión de videos Revista Argentina De Clinica Psicologica. 19: 45-56.  0.01
1945 BERNALES SE. [Not Available]. Actualidad MéDica Peruana. 11: 75 107 135 passim. PMID 21026482  0.01
Hide low-probability matches.