☰

Shikhar Sharma, Ph.D. - Publications

Affiliations: 
2010 Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Area:
DNA methylation, cancer, epigenetics
Tree Info Grants Similar researchers PubMed Report error

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Qiu J, Sharma S, Rollins RA, Paul TA. The complex role of EZH2 in the tumor microenvironment: opportunities and challenges for immunotherapy combinations. Future Medicinal Chemistry. PMID 32723083 DOI: 10.4155/Fmc-2020-0072  0.307
2020 Rugo HS, Jacobs I, Sharma S, Scappaticci F, Paul TA, Jensen-Pergakes K, Malouf GG. The Promise for Histone Methyltransferase Inhibitors for Epigenetic Therapy in Clinical Oncology: A Narrative Review. Advances in Therapy. PMID 32445185 DOI: 10.1007/S12325-020-01379-X  0.415
2017 Kung PP, Bingham P, Brooun A, Collins MR, Deng YL, Dinh DM, Fan C, Gajiwala KS, Grantner R, Gukasyan HJ, Hu W, Huang B, Kania RS, Kephart SE, Krivacic CT, ... ... Sharma S, et al. Optimization of orally bioavailable enhancer of zeste homolog 2 (EZH2) inhibitors using ligand and property-based design strategies: Identification of development candidate (R)-5,8-dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497). Journal of Medicinal Chemistry. PMID 29211475 DOI: 10.1021/Acs.Jmedchem.7B01375  0.303
2015 Vangamudi B, Paul TA, Shah PK, Kost-Alimova M, Nottebaum L, Shi X, Zhan Y, Leo E, Mahadeshwar HS, Protopopov A, Futreal A, Tieu TN, Peoples M, Heffernan TP, Marszalek JR, ... ... Sharma S, et al. The SMARCA2/4 ATPase domain surpasses the bromodomain as a drug target in SWI/SNF mutant cancers: Insights from cDNA rescue and PFI-3 inhibitor studies. Cancer Research. PMID 26139243 DOI: 10.1158/0008-5472.Can-14-3798  0.369
2015 Vangamudi B, Paul T, Shah PK, Alimova MK, Nottebaum L, Shi X, Zhan Y, Leo E, Mahadeshwar HS, Protopopov A, Futreal A, Tieu TN, Peoples M, Petrocchi A, Marszalek JR, ... ... Sharma S, et al. Abstract 3528: The SMARCA2/4 catalytic activity, but not the bromodomain, is a drug target in SWI/SNF mutant cancers Cancer Research. 75: 3528-3528. DOI: 10.1158/1538-7445.Am2015-3528  0.376
2015 Paul TA, Sharma S, Hallin J, Xie T, Nichols T, Greig M, Hardwick J, Wythes M, Verhelle D. Abstract 3518: Growth inhibition of SCLC cell lines by treatment with LSD1 inhibitors is associated with modulation of neuroendocrine pathways Cancer Research. 75: 3518-3518. DOI: 10.1158/1538-7445.Am2015-3518  0.375
2012 De Carvalho DD, Sharma S, You JS, Su SF, Taberlay PC, Kelly TK, Yang X, Liang G, Jones PA. DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell. 21: 655-67. PMID 22624715 DOI: 10.1016/J.Ccr.2012.03.045  0.645
2012 Sharma S, Gerke DS, Han HF, Jeong S, Stallcup MR, Jones PA, Liang G. Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells. Epigenetics & Chromatin. 5: 3. PMID 22284370 DOI: 10.1186/1756-8935-5-3  0.606
2011 Sharma S, De Carvalho DD, Jeong S, Jones PA, Liang G. Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. Plos Genetics. 7: e1001286. PMID 21304883 DOI: 10.1371/Journal.Pgen.1001286  0.562
2010 Wolff EM, Byun HM, Han HF, Sharma S, Nichols PW, Siegmund KD, Yang AS, Jones PA, Liang G. Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. Plos Genetics. 6: e1000917. PMID 20421991 DOI: 10.1371/Journal.Pgen.1000917  0.653
2010 Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis. 31: 27-36. PMID 19752007 DOI: 10.1093/Carcin/Bgp220  0.533
2010 Liang G, Wolff EM, Han HF, Byun H, Sharma S, Nichols P, Siegmund KD, Jones PA. Abstract 4801: Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer Cancer Research. 70: 4801-4801. DOI: 10.1158/1538-7445.Am10-4801  0.648
2009 Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA. Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Molecular and Cellular Biology. 29: 5366-76. PMID 19620278 DOI: 10.1128/Mcb.00484-09  0.666
2008 Weisenberger DJ, Trinh BN, Campan M, Sharma S, Long TI, Ananthnarayan S, Liang G, Esteva FJ, Hortobagyi GN, McCormick F, Jones PA, Laird PW. DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight. Nucleic Acids Research. 36: 4689-98. PMID 18628296 DOI: 10.1093/nar/gkn455  0.459
Show low-probability matches.