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Ethan C. Settembre, Ph.D. - Publications

Affiliations: 
2004 Cornell University, Ithaca, NY, United States 
Area:
structure and function of proteins using X-ray crystallography
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Soriano EV, Zhang Y, Colabroy KL, Sanders JM, Settembre EC, Dorrestein PC, Begley TP, Ealick SE. Active-site models for complexes of quinolinate synthase with substrates and intermediates. Acta Crystallographica. Section D, Biological Crystallography. 69: 1685-96. PMID 23999292 DOI: 10.1107/S090744491301247X  0.549
2011 Lo Surdo P, Bottomley MJ, Calzetta A, Settembre EC, Cirillo A, Pandit S, Ni YG, Hubbard B, Sitlani A, Carfí A. Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH. Embo Reports. 12: 1300-5. PMID 22081141 DOI: 10.1038/embor.2011.205  0.32
2010 Paul D, O'Leary SE, Rajashankar K, Bu W, Toms A, Settembre EC, Sanders JM, Begley TP, Ealick SE. Glycal formation in crystals of uridine phosphorylase. Biochemistry. 49: 3499-509. PMID 20364833 DOI: 10.1021/Bi902073B  0.656
2005 Bu W, Settembre EC, el Kouni MH, Ealick SE. Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines. Acta Crystallographica. Section D, Biological Crystallography. 61: 863-72. PMID 15983408 DOI: 10.1107/S0907444905007882  0.645
2004 Settembre EC, Chittuluru JR, Mill CP, Kappock TJ, Ealick SE. Acidophilic adaptations in the structure of Acetobacter aceti N5-carboxyaminoimidazole ribonucleotide mutase (PurE). Acta Crystallographica. Section D, Biological Crystallography. 60: 1753-60. PMID 15388921 DOI: 10.1107/S090744490401858X  0.609
2004 Settembre EC, Dorrestein PC, Zhai H, Chatterjee A, McLafferty FW, Begley TP, Ealick SE. Thiamin biosynthesis in Bacillus subtilis: structure of the thiazole synthase/sulfur carrier protein complex. Biochemistry. 43: 11647-57. PMID 15362849 DOI: 10.1021/Bi0488911  0.65
2004 Lee JE, Settembre EC, Cornell KA, Riscoe MK, Sufrin JR, Ealick SE, Howell PL. Structural comparison of MTA phosphorylase and MTA/AdoHcy nucleosidase explains substrate preferences and identifies regions exploitable for inhibitor design. Biochemistry. 43: 5159-69. PMID 15122881 DOI: 10.1021/Bi035492H  0.616
2003 Settembre E, Begley TP, Ealick SE. Structural biology of enzymes of the thiamin biosynthesis pathway. Current Opinion in Structural Biology. 13: 739-47. PMID 14675553 DOI: 10.1016/J.Sbi.2003.10.006  0.627
2003 Settembre EC, Dorrestein PC, Park JH, Augustine AM, Begley TP, Ealick SE. Structural and mechanistic studies on ThiO, a glycine oxidase essential for thiamin biosynthesis in Bacillus subtilis. Biochemistry. 42: 2971-81. PMID 12627963 DOI: 10.1021/Bi026916V  0.661
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